SB0049 : [beta]-Neoendorphin-dynorphin
[ CaMP Format ]
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | proenkephalin-B preproprotein [Mus musculus]; proenkephalin-B preproprotein; proenkephalin-B; preprodynorphin; beta-neoendorphin-dynorphin; alpha-neoendorphin; leu-enkephalin; big dynorphin; dynorphin A(1-17); dynorphin A(1-13); dynorphin A(1-8); leumorphin; rimorphin |
| Gene Names | Pdyn; prodynorphin |
| Gene Locus | 2 63.19 cM; chromosome 2 |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 248 aa
Average Mass: 28.009 kDa
Monoisotopic Mass: 27.992 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Vertebrate endogenous opioids neuropeptide 1. | 22 | 66 | 1.0 | 3.4 |
3. Sequence Information
Fasta Sequence: SB0049.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
2 [sites] cleaved by Calpain 1 and 2
Source Reference: [PubMed ID: 6092335] Sasaki T, Kikuchi T, Yumoto N, Yoshimura N, Murachi T, Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates. J Biol Chem. 1984 Oct 25;259(20):12489-94.
Cleavage sites (±10aa)
[Site 1] LYKRYGGFLR207-RIRPKLKWDN
Arg207 
Arg
iTraq-117 Signal 14116.5 (
) for LYKRYGGFLR
iTraq-117 Signal 7582.7 () for RIRPKLK
iTraq-117 Signal 6159.0 () for RIRPKLKWDN
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Leu198 | Tyr199 | Lys200 | Arg201 | Tyr202 | Gly203 | Gly204 | Phe205 | Leu206 | Arg207 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Arg208 | Ile209 | Arg210 | Pro211 | Lys212 | Leu213 | Lys214 | Trp215 | Asp216 | Asn217 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| SEMARDEDGGQDGDQVGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQE |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 127.00 | 12 | PDYN_MOUSE Beta-neoendorphin-dynorphin precursor |
| 2 | Mus musculus | 127.00 | 5 | beta-neoendorphin-dynorphin preproprotein |
| 3 | Rattus norvegicus | 119.00 | 4 | prodynorphin |
| 4 | mice, brain, Peptide Partial, 63 aa | 115.00 | 1 | AAB29180.1 |
| 5 | Canis familiaris | 105.00 | 6 | PREDICTED: similar to Beta-neoendorphin-dynorphin |
| 6 | Sus scrofa | 104.00 | 1 | beta-neoendorphin-dynorphin preproprotein |
| 7 | Homo sapiens | 103.00 | 6 | beta-neoendorphin-dynorphin preproprotein |
| 8 | Pan paniscus | 102.00 | 1 | preprodynorphin |
| 9 | Gorilla gorilla | 102.00 | 1 | preprodynorphin |
| 10 | Pan troglodytes verus | 102.00 | 1 | preprodynorphin |
| 11 | Pongo abelii | 102.00 | 1 | preprodynorphin |
| 12 | Macaca nemestrina | 102.00 | 1 | preprodynorphin |
| 13 | Papio papio | 102.00 | 1 | preprodynorphin |
| 14 | Macaca mulatta | 102.00 | 1 | preprodynorphin |
| 15 | Bos taurus | 89.40 | 4 | beta-neoendorphin-dynorphin preproprotein |
| 16 | Xenopus laevis | 77.80 | 4 | dorphin A |
| 17 | Danio rerio | 73.20 | 8 | prodynorphin |
| 18 | Bufo marinus | 63.20 | 1 | AF084455_1 prodynorphin |
| 19 | Oncorhynchus masou | 62.00 | 1 | prodynorphin |
| 20 | Neoceratodus forsteri | 50.80 | 1 | AF232671_1 proenkephalin |
| 21 | Protopterus annectens | 50.40 | 1 | AF232670_1 proenkephalin |
| 22 | Polypterus senegalus | 38.10 | 1 | proenkephalin B |
| 23 | Mus musculus | 37.70 | 1 | developmental-regulatd molecule |
| 24 | Gallus gallus | 35.80 | 1 | PREDICTED: similar to proenkephalin |
| 25 | Tetraodon nigroviridis | 35.40 | 2 | unnamed protein product |
| 26 | Amphiuma means | 35.00 | 1 | proenkephalin |
| 27 | Rattus sp. | 33.90 | 1 | ORL1 receptor agonist precursor |
| 28 | Contains: Synenkephalin; Met-enkephalin; Leu-enkephalin | 33.50 | 1 | PENK_FELCA Proenkephalin A |
| 29 | Necturus maculosus | 33.10 | 1 | proenkephalin |
| 30 | Spea multiplicata | 32.30 | 1 | AF195886_1 proenkephalin |
| 31 | synthetic construct | 32.00 | 4 | prepronociceptin |
| 32 | Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | 32.00 | 2 | PENK_CAVPO Proenkephalin A precursor |
| 33 | Contains: Synenkephalin; Met-enkephalin; Met-enkephalin-Arg-Gly-Tyr; Met-enkephalin-Arg-Phe | 31.60 | 1 | PENKA_XENLA Proenkephalin A-A precursor |
| 34 | Xenopus tropicalis | 31.60 | 1 | MGC107924 protein |
| 35 | Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Tyr; Met-enkephalin-Arg-Phe | 31.20 | 1 | PENKB_XENLA Proenkephalin A-B precursor |
| 36 | Bacillus clausii KSM-K16 | 31.20 | 1 | DNA topoisomerase I |
| 37 | Bacillus sp. NRRL B-14911 | 30.80 | 1 | DNA topoisomerase I |
| 38 | Acipenser transmontanus | 30.80 | 1 | AF095739_1 proorphanin |
| 39 | Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | 30.40 | 1 | PENK_RAT Proenkephalin A precursor |
| 40 | Cricetinae | 30.40 | 1 | preproenkephalin A |
| 41 | Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | 30.40 | 1 | PENK_MOUSE Proenkephalin A precursor |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 178 SEMARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 178 SEMARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 |
| Mus musculus | Query 178 SEMARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 178 SEMARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 |
| Rattus norvegicus | Query 178 SEMARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 |||| ||| |||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 134 SEMAGDEDRGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 193 |
| mice, brain, Peptide Partial, 63 aa | Query 178 SEMARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVT 233 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||| Query 178 SEMARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVT 233 |
| Canis familiaris | Query 185 DGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 +| ||| |||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 192 EGNGDGDAVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 244 |
| Sus scrofa | Query 178 SEMARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||+| + || | |+|||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 187 SEVAGEGDG--DRDKVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 244 |
| Homo sapiens | Query 189 DGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||| +||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 194 DGDSMGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 242 |
| Pan paniscus | Query 189 DGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||| ||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 151 DGDSTGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 199 |
| Gorilla gorilla | Query 189 DGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||| +||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 151 DGDSMGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 199 |
| Pan troglodytes verus | Query 189 DGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||| ||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 151 DGDSTGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 199 |
| Pongo abelii | Query 189 DGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||| +||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 151 DGDSMGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 199 |
| Macaca nemestrina | Query 189 DGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||| +||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 150 DGDSMGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 198 |
| Papio papio | Query 189 DGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||| +||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 150 DGDSMGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 198 |
| Macaca mulatta | Query 189 DGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||| +||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 150 DGDSMGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 198 |
| Bos taurus | Query 197 DLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 |||||||||||#|||||||||||||||||||||||||||||| Query 197 DLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 |
| Xenopus laevis | Query 185 DGGQDGD-QVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 + ||+ | + | +| ||||||||#||||||+||||||||||||||||| ||+| Sbjct 182 ETGQEVDLEHGTAELEKRYGGFLR#RIRPKLRWDNQKRYGGFLRRQFKVNARSEE 235 |
| Danio rerio | Query 191 DQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 | + | ||||||+|#||||||+||||||||||||| ||+ || | Sbjct 196 DDTNPQVLQKRYGGFMR#RIRPKLRWDNQKRYGGFLRRHFKISVRSDE 242 |
| Bufo marinus | Query 207 R#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 |#|||||||||||||||||||||||| |||+| Sbjct 1 R#RIRPKLKWDNQKRYGGFLRRQFKVTTRSEE 31 |
| Oncorhynchus masou | Query 200 KRYGGFLR#RIRPKL------KWDNQKRYGGFLRRQFKVVTRSQE 237 ||||||+|#|||||| |||||||||||||| +|+ || | Sbjct 1 KRYGGFMR#RIRPKLNNLNTMKWDNQKRYGGFLRRHYKLSVRSDE 44 |
| Neoceratodus forsteri | Query 188 QDGDQVGHEDLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRR 227 | | | +|| ||||||+|#|+ ||+ | |||||||||+|| Sbjct 197 SDQDDVA-KDLQKRYGGFMR#RVGRPEWKLDNQKRYGGFMRR 236 |
| Protopterus annectens | Query 197 DLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRR 227 || ||||||+|#|+ ||+ | |||||||||+|| Sbjct 204 DLQKRYGGFMR#RVGRPEWKLDNQKRYGGFMRR 235 |
| Polypterus senegalus | Query 194 GHEDLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRR 227 | +|| ||||||+|#|+ || | +|||||||| +| Sbjct 200 GIKDLQKRYGGFMR#RVGRPDWK-ENQKRYGGFFKR 233 Query 183 DEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKW-----DNQKRYGGFLRR 227 + | +|| | ++ ||||||+|# |+ | | |||||||+|| Sbjct 167 ESDMESNGDHDG--EILKRYGGFMR#SIKRSLDLEDGIKDLQKRYGGFMRR 214 |
| Mus musculus | Query 181 ARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 | | | | ++| + | ||+||| # + | ||||+ |+|+ + +| + Sbjct 120 ADAEPGADDAEEVEQKQLQKRFGGFTG#ARKSARKLANQKRFSEFMRQYLVLSMQSSQ 176 |
| Gallus gallus | Query 197 DLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 +| ||||||+|#|+ ||+ | ||||||||+| + |+| Sbjct 204 ELQKRYGGFMR#RVGRPEWWLDYQKRYGGFLKRFADSILPSEE 245 Query 197 DLYKRYGGFLR#RIR--PKLKWDN---QKRYGGFLRR 227 |+ ||||||+|# ++ |+|+ + |||||||+|| Sbjct 180 DVSKRYGGFMR#SVKRSPELEDEAKELQKRYGGFMRR 215 |
| Tetraodon nigroviridis | Query 180 MARDEDGGQDGD---QVGHEDLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRRQF 229 | | |+| || | | ||||||+|#|+ ||+ |+ || || |+| + Sbjct 179 MRRAEEGAAQGDLLEAVLGRGLKKRYGGFMR#RVGRPEWLVDSSKR-GGVLKRAW 231 |
| Amphiuma means | Query 194 GHEDLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRR 227 | +||+||||||+|#|+ ||+ | |||||||+|| Sbjct 198 GAKDLHKRYGGFMR#RVGRPEWWQDYQKRYGGFMRR 232 Query 189 DGDQVGHEDLYKRYGGFLR#RIR--PKLKW---DNQKRYGGFLRR 227 | + |+ ||||||+|# |+ |+++ | ||||||+|| Sbjct 169 DSNSESQGDVSKRYGGFMR#GIKRSPEMEEGAKDLHKRYGGFMRR 212 |
| Rattus sp. | Query 181 ARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVT 233 | | + |+| + | ||+||| # + | ||||+ |+ ||+ |++ Sbjct 101 ADAEPVADEADEVEQKQLQKRFGGFTG#ARKSARKLANQKRFSEFM-RQYLVLS 152 |
| Contains: Synenkephalin; Met-enkephalin; Leu-enkephalin | Query 198 LYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRR 227 | ||||||+|#|+ ||+ | ||||||||+| Sbjct 142 LQKRYGGFMR#RVGRPEWWMDYQKRYGGFLKR 172 Query 196 EDLYKRYGGFLR#RIR--PKLKWDN---QKRYGGFLRR 227 ||+ | +|||+|# ++ |+| + |||||||+|| Sbjct 116 EDVSKSHGGFMR#ALKGSPQLAQEAKMLQKRYGGFMRR 152 |
| Necturus maculosus | Query 194 GHEDLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRR 227 | +||+||||||+|#|+ ||+ | |||||||+|| Sbjct 198 GAKDLHKRYGGFMR#RVGRPEWWLDYQKRYGGFMRR 232 Query 197 DLYKRYGGFLR#RIR--PKLKW---DNQKRYGGFLRR 227 ++ ||||||+|# ++ |+++ | ||||||+|| Sbjct 177 EVSKRYGGFMR#EVKRSPEMEEGAKDLHKRYGGFMRR 212 |
| Spea multiplicata | Query 197 DLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 +++||||||+|#|+ ||+ | |||||||+|| | | | Sbjct 197 EMHKRYGGFMR#RVGRPEWWQDYQKRYGGFMRRFSDSVLPSDE 238 Query 200 KRYGGFLR#RI----RPKLKWDNQ------KRYGGFLRRQF 229 ||||||++#++ ||+ + || |+||||++++| Sbjct 103 KRYGGFMK#KMDELYRPEAEEDNNGGEILAKKYGGFMKKEF 142 Query 178 SEMARDEDGGQDGDQVGHED-------LYKRYGGFLR#RIRPKLKWDNQ-----KRYGGFL 225 +++ |+ | | + + + | + ||||||+|# | +++ ||||||+ Sbjct 147 ADLLRELLGSNDPEAISYHDNNEIPGEINKRYGGFMR#NYRRSPDVEDEAREMHKRYGGFM 206 Query 226 RR 227 || Query 226 RR 227 |
| synthetic construct | Query 179 EMARDEDGGQDGDQVGHEDLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKVVT 233 | | | ++ ++ + | ||+||| # + | ||||+ |+ ||+ |++ Sbjct 107 EQEEPEPGMEEAGEMEQKQLQKRFGGFTG#ARKSARKLANQKRFSEFM-RQYLVLS 160 |
| Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | Query 197 DLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 +| ||||||+|#|+ ||+ | ||||||||+| + + +| Sbjct 206 ELQKRYGGFMR#RVGRPEWWMDYQKRYGGFLKRFAEFLPSDEE 247 Query 196 EDLYKRYGGFLR#RIR--PKLKWDN---QKRYGGFLRR 227 | + ||||||+|# ++ |+++ + |||||||+|| Sbjct 181 EGVSKRYGGFMR#GLKRSPQVEDEAKELQKRYGGFMRR 217 |
| Contains: Synenkephalin; Met-enkephalin; Met-enkephalin-Arg-Gly-Tyr; Met-enkephalin-Arg-Phe | Query 200 KRYGGFLR#RI-RPKLKWDNQKRYGGFLRR 227 ||||||+|#|+ ||+ | |||||||+ | Sbjct 202 KRYGGFMR#RVGRPEWWEDYQKRYGGFMTR 230 Query 197 DLYKRYGGFLR#RIRPKLKWDN-----QKRYGGFLRR 227 ++ ||||||+|# | ++ |||||||+|| Sbjct 175 EINKRYGGFMR#GYRRSTDLEDETSGIQKRYGGFMRR 210 |
| Xenopus tropicalis | Query 200 KRYGGFLR#RI-RPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 ||||||+|#|+ ||+ | |||||||+|| |+| Sbjct 202 KRYGGFMR#RVGRPEWWQDYQKRYGGFMRRFTDSFLPSEE 240 Query 197 DLYKRYGGFLR#RIRPKLKWDN-----QKRYGGFLRR 227 ++ ||||||+|# | ++ |||||||+|| Sbjct 175 EMNKRYGGFMR#GYRRSTDLEDETRGIQKRYGGFMRR 210 |
| Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Tyr; Met-enkephalin-Arg-Phe | Query 200 KRYGGFLR#RI-RPKLKWDNQKRYGGFLRR 227 ||||||+|#|+ ||+ | |||||||+ | Sbjct 156 KRYGGFMR#RVGRPEWWQDYQKRYGGFMTR 184 Query 197 DLYKRYGGFLR#RIRPKLKWDN-----QKRYGGFLRR 227 ++ ||||||+|# | ++ |||||||+|| Sbjct 129 EMNKRYGGFMR#GYRRSTDLEDETRGIQKRYGGFMRR 164 |
| Bacillus clausii KSM-K16 | Query 182 RDEDGGQDGDQVGHEDLYK--RYGGFL 206 +|| |+| ++ ||| +|| ||| |+ Sbjct 571 KDEPAGEDCEKCGHEMVYKMGRYGKFM 597 |
| Bacillus sp. NRRL B-14911 | Query 182 RDEDGGQDGDQVGHEDLYK--RYGGFL 206 +|| |+| ++ ||| +|| ||| |+ Sbjct 571 KDEPAGEDCEKCGHEMVYKMGRYGKFM 597 |
| Acipenser transmontanus | Query 197 DLYKRYGGFLR#RIRPKLKWDNQKRYGGFLRRQFKV 231 | ||||||+ # + ||+| ||| |++ + Sbjct 156 SLQKRYGGFIG#IRKSARKWNNPKRYNELLKQYLGI 190 |
| Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | Query 197 DLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 +| ||||||+|#|+ ||+ | ||||||||+| + + +| Sbjct 207 ELQKRYGGFMR#RVGRPEWWMDYQKRYGGFLKRFAESLPSDEE 248 Query 200 KRYGGFLR#RIR--PKLKWDN---QKRYGGFLRR 227 ||||||+|# ++ |+|+ + |||||||+|| Sbjct 186 KRYGGFMR#GLKRSPQLEDEAKELQKRYGGFMRR 218 Query 197 DLYKRYGGFLR#RIRPKLKWDN------------QKRYGGFLR 226 | |||||||+#| | | +||||||+| Sbjct 227 DYQKRYGGFLK#RFAESLPSDEEGESYSKEVPEMEKRYGGFMR 268 |
| Cricetinae | Query 197 DLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 +| ||||||+|#|+ ||+ | ||||||||+| + + +| Sbjct 206 ELQKRYGGFMR#RVGRPEWWMDYQKRYGGFLKRFAESLPSDEE 247 Query 196 EDLYKRYGGFLR#RIR--PKLKWDN---QKRYGGFLRR 227 +++ ||||||+|# ++ |+++ + |||||||+|| Sbjct 181 DNMSKRYGGFMR#GLKRSPQVEDEAKELQKRYGGFMRR 217 Query 197 DLYKRYGGFLR#RIRPKLKWDN------------QKRYGGFLR 226 | |||||||+#| | | +||||||+| Sbjct 226 DYQKRYGGFLK#RFAESLPSDEEAESYSKEVPEIEKRYGGFMR 267 |
| Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | Query 197 DLYKRYGGFLR#RI-RPKLKWDNQKRYGGFLRRQFKVVTRSQE 237 +| ||||||+|#|+ ||+ | ||||||||+| + + +| Sbjct 207 ELQKRYGGFMR#RVGRPEWWMDYQKRYGGFLKRFAESLPSDEE 248 Query 182 RDEDGGQDGDQVGHEDLY-KRYGGFLR#RIR--PKLKWDN---QKRYGGFLRR 227 | +| | ||+ ||||||+|# ++ |+|+ + |||||||+|| Sbjct 167 RAKDSHQQESTNNDEDMSSKRYGGFMR#SLKRSPQLEDEAKELQKRYGGFMRR 218 Query 197 DLYKRYGGFLR#RIRPKLKWDN------------QKRYGGFLR 226 | |||||||+#| | | +||||||+| Sbjct 227 DYQKRYGGFLK#RFAESLPSDEEGENYSKEVPEIEKRYGGFMR 268 |
[Site 2] FLRRIRPKLK214-WDNQKRYGGF
Lys214 Trp
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Phe205 | Leu206 | Arg207 | Arg208 | Ile209 | Arg210 | Pro211 | Lys212 | Leu213 | Lys214 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Trp215 | Asp216 | Asn217 | Gln218 | Lys219 | Arg220 | Tyr221 | Gly222 | Gly223 | Phe224 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| DGGQDGDQVGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQENPNTYSE |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 129.00 | 12 | PDYN_MOUSE Beta-neoendorphin-dynorphin precursor |
| 2 | Mus musculus | 129.00 | 5 | beta-neoendorphin-dynorphin preproprotein |
| 3 | Rattus norvegicus | 125.00 | 4 | beta-neoendorphin-dynorphin preproprotein |
| 4 | Canis familiaris | 114.00 | 6 | PREDICTED: similar to Beta-neoendorphin-dynorphin |
| 5 | Homo sapiens | 112.00 | 6 | beta-neoendorphin-dynorphin preproprotein |
| 6 | Pongo abelii | 112.00 | 1 | preprodynorphin |
| 7 | Macaca mulatta | 112.00 | 1 | preprodynorphin |
| 8 | Macaca nemestrina | 112.00 | 1 | preprodynorphin |
| 9 | Pan paniscus | 112.00 | 1 | preprodynorphin |
| 10 | Gorilla gorilla | 112.00 | 1 | preprodynorphin |
| 11 | Papio papio | 112.00 | 1 | preprodynorphin |
| 12 | Pan troglodytes verus | 112.00 | 1 | preprodynorphin |
| 13 | Sus scrofa | 110.00 | 1 | beta-neoendorphin-dynorphin preproprotein |
| 14 | mice, brain, Peptide Partial, 63 aa | 101.00 | 1 | AAB29180.1 |
| 15 | Bos taurus | 95.90 | 3 | beta-neoendorphin-dynorphin preproprotein |
| 16 | Xenopus laevis | 84.30 | 4 | dorphin A |
| 17 | Danio rerio | 79.30 | 8 | prodynorphin |
| 18 | Bufo marinus | 71.20 | 1 | AF084455_1 prodynorphin |
| 19 | Oncorhynchus masou | 67.80 | 1 | prodynorphin |
| 20 | Neoceratodus forsteri | 54.30 | 1 | AF232671_1 proenkephalin |
| 21 | Necturus maculosus | 51.20 | 1 | proenkephalin |
| 22 | Protopterus annectens | 50.80 | 1 | AF232670_1 proenkephalin |
| 23 | Amphiuma means | 50.40 | 1 | proenkephalin |
| 24 | Gallus gallus | 48.90 | 1 | PREDICTED: similar to proenkephalin |
| 25 | Xenopus tropicalis | 45.10 | 1 | MGC107924 protein |
| 26 | Polypterus senegalus | 37.70 | 1 | proenkephalin B |
| 27 | Mus musculus | 37.00 | 1 | developmental-regulatd molecule |
| 28 | Contains: Synenkephalin; Met-enkephalin; Leu-enkephalin | 33.90 | 1 | PENK_FELCA Proenkephalin A |
| 29 | Tetraodon nigroviridis | 33.50 | 2 | unnamed protein product |
| 30 | Spea multiplicata | 33.50 | 1 | AF195886_1 proenkephalin |
| 31 | Rattus sp. | 33.50 | 1 | ORL1 receptor agonist precursor |
| 32 | Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | 32.30 | 2 | PENK_CAVPO Proenkephalin A precursor |
| 33 | Contains: Synenkephalin; Met-enkephalin; Met-enkephalin-Arg-Gly-Tyr; Met-enkephalin-Arg-Phe | 32.00 | 1 | PENKA_XENLA Proenkephalin A-A precursor |
| 34 | Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Tyr; Met-enkephalin-Arg-Phe | 31.60 | 1 | PENKB_XENLA Proenkephalin A-B precursor |
| 35 | Roseovarius sp. 217 | 31.20 | 1 | branched chain amino acid ABC transporter ATP-bin |
| 36 | synthetic construct | 30.80 | 4 | proenkephalin |
| 37 | Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | 30.40 | 1 | PENK_MOUSE Proenkephalin A precursor |
| 38 | Cricetinae | 30.40 | 1 | preproenkephalin A |
| 39 | Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | 30.40 | 1 | PENK_RAT Proenkephalin A precursor |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 |
| Mus musculus | Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 |
| Rattus norvegicus | Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 | ||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 185 DRGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 |
| Canis familiaris | Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 +| ||| ||||||||||||||||||||||#|||||||||||||||||||||||+|| || Sbjct 192 EGNGDGDAVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYS 250 |
| Homo sapiens | Query 186 GGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 | ||| +|||||||||||||||||||||#|||||||||||||||||||||||+|| || Sbjct 191 GEGDGDSMGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYS 248 |
| Pongo abelii | Query 186 GGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 | ||| +|||||||||||||||||||||#|||||||||||||||||||||||+|| || Sbjct 148 GEGDGDSMGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYS 205 |
| Macaca mulatta | Query 189 DGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 ||| +|||||||||||||||||||||#|||||||||||||||||||||||+|| || Sbjct 150 DGDSMGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYS 204 |
| Macaca nemestrina | Query 189 DGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 ||| +|||||||||||||||||||||#|||||||||||||||||||||||+|| || Sbjct 150 DGDSMGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYS 204 |
| Pan paniscus | Query 186 GGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 | ||| |||||||||||||||||||||#|||||||||||||||||||||||+|| || Sbjct 148 GEGDGDSTGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYS 205 |
| Gorilla gorilla | Query 186 GGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 | ||| +|||||||||||||||||||||#|||||||||||||||||||||||+|| || Sbjct 148 GEGDGDSMGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYS 205 |
| Papio papio | Query 189 DGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 ||| +|||||||||||||||||||||#|||||||||||||||||||||||+|| || Sbjct 150 DGDSMGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYS 204 |
| Pan troglodytes verus | Query 186 GGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 | ||| |||||||||||||||||||||#|||||||||||||||||||||||+|| || Sbjct 148 GEGDGDSTGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYS 205 |
| Sus scrofa | Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 +| | |+||||||||||||||||||||||#|||||||||||||||||||||||+|| | | Sbjct 192 EGDGDRDKVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPNAYYE 251 |
| mice, brain, Peptide Partial, 63 aa | Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVT 233 ||||||||||||||||||||||||||||||#||||||||||||||||||| Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVT 233 |
| Bos taurus | Query 197 DLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 ||||||||||||||||||#|||||||||||||||||||||||+|+ | | Sbjct 206 DLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQEDPSAYYE 253 |
| Xenopus laevis | Query 185 DGGQDGD-QVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 + ||+ | + | +| ||||||||||||||+#||||||||||||||||| ||+|+| +| Sbjct 182 ETGQEVDLEHGTAELEKRYGGFLRRIRPKLR#WDNQKRYGGFLRRQFKVNARSEEDPTMFS 241 |
| Danio rerio | Query 191 DQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 | + | ||||||+|||||||+#||||||||||||| ||+ || | |++| + Sbjct 196 DDTNPQVLQKRYGGFMRRIRPKLR#WDNQKRYGGFLRRHFKISVRSDEEPSSYED 249 |
| Bufo marinus | Query 207 RRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 ||||||||#||||||||||||||||| |||+|+|+|+| Sbjct 1 RRIRPKLK#WDNQKRYGGFLRRQFKVTTRSEEDPSTFS 37 |
| Oncorhynchus masou | Query 200 KRYGGFLRRIRPKL------K#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 ||||||+||||||| |#||||||||||||| +|+ || | |++| + Sbjct 1 KRYGGFMRRIRPKLNNLNTMK#WDNQKRYGGFLRRHYKLSVRSDEEPSSYDD 51 |
| Neoceratodus forsteri | Query 188 QDGDQVGHEDLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 | | | +|| ||||||+||+ ||+ |# |||||||||+|| | | |+ || Sbjct 197 SDQDDVA-KDLQKRYGGFMRRVGRPEWK#LDNQKRYGGFMRR-FADALLSDEDGEIYS 251 |
| Necturus maculosus | Query 194 GHEDLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 | +||+||||||+||+ ||+ # | |||||||+|| | |+ +|| Sbjct 198 GAKDLHKRYGGFMRRVGRPEWW#LDYQKRYGGFMRRFADYSAPSDEDGESYS 248 |
| Protopterus annectens | Query 197 DLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRR 227 || ||||||+||+ ||+ |# |||||||||+|| Sbjct 204 DLQKRYGGFMRRVGRPEWK#LDNQKRYGGFMRR 235 |
| Amphiuma means | Query 194 GHEDLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 | +||+||||||+||+ ||+ # | |||||||+|| | |+ +|| Sbjct 198 GAKDLHKRYGGFMRRVGRPEWW#QDYQKRYGGFMRRFTDYSAPSDEDGESYS 248 |
| Gallus gallus | Query 196 EDLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 ++| ||||||+||+ ||+ # | ||||||||+| + |+|+ |||+ Sbjct 203 KELQKRYGGFMRRVGRPEWW#LDYQKRYGGFLKRFADSILPSEEDGETYSK 252 |
| Xenopus tropicalis | Query 198 LYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 + ||||||+||+ ||+ # | |||||||+|| |+|+ +|| Sbjct 200 IQKRYGGFMRRVGRPEWW#QDYQKRYGGFMRRFTDSFLPSEEDGESYS 246 |
| Polypterus senegalus | Query 194 GHEDLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRR 227 | +|| ||||||+||+ || |# +|||||||| +| Sbjct 200 GIKDLQKRYGGFMRRVGRPDWK#-ENQKRYGGFFKR 233 Query 185 DGGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDN-----QKRYGGFLRR 227 | +|| | ++ ||||||+| |+ | # ++ |||||||+|| Sbjct 169 DMESNGDHDG--EILKRYGGFMRSIKRSLD#LEDGIKDLQKRYGGFMRR 214 |
| Mus musculus | Query 186 GGQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNT 241 | | ++| + | ||+||| + |# ||||+ |+|+ + +| + | Sbjct 125 GADDAEEVEQKQLQKRFGGFTGARKSARK#LANQKRFSEFMRQYLVLSMQSSQRRRT 180 |
| Contains: Synenkephalin; Met-enkephalin; Leu-enkephalin | Query 198 LYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 | ||||||+||+ ||+ # | ||||||||+| | | | +|| Sbjct 142 LQKRYGGFMRRVGRPEWW#MDYQKRYGGFLKR-FADSLPSDEEGESYS 187 Query 196 EDLYKRYGGFLRRIR--PKLK#WDN---QKRYGGFLRR 227 ||+ | +|||+| ++ |+| # + |||||||+|| Sbjct 116 EDVSKSHGGFMRALKGSPQLA#QEAKMLQKRYGGFMRR 152 |
| Tetraodon nigroviridis | Query 200 KRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQE 237 ||||||+ + |#|+||||+ ||++ + |+ + Sbjct 70 KRYGGFVGIRKSARK#WNNQKRFSEFLKQYLGMSARTTD 107 |
| Spea multiplicata | Query 197 DLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 +++||||||+||+ ||+ # | |||||||+|| | | |+ +|| Sbjct 197 EMHKRYGGFMRRVGRPEWW#QDYQKRYGGFMRRFSDSVLPSDEDGESYS 244 Query 198 LYKRYGGFLRRI----RPKLK#WDN------QKRYGGFLRRQF 229 ||||||++++ ||+ +# || |+||||++++| Sbjct 101 FMKRYGGFMKKMDELYRPEAE#EDNNGGEILAKKYGGFMKKEF 142 |
| Rattus sp. | Query 187 GQDGDQVGHEDLYKRYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVT 233 + |+| + | ||+||| + |# ||||+ |+ ||+ |++ Sbjct 107 ADEADEVEQKQLQKRFGGFTGARKSARK#LANQKRFSEFM-RQYLVLS 152 |
| Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | Query 197 DLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 +| ||||||+||+ ||+ # | ||||||||+| | | | +|| Sbjct 206 ELQKRYGGFMRRVGRPEWW#MDYQKRYGGFLKR-FAEFLPSDEEGESYS 252 Query 196 EDLYKRYGGFLRRIR--PKLK#WDN---QKRYGGFLRR 227 | + ||||||+| ++ |+++# + |||||||+|| Sbjct 181 EGVSKRYGGFMRGLKRSPQVE#DEAKELQKRYGGFMRR 217 |
| Contains: Synenkephalin; Met-enkephalin; Met-enkephalin-Arg-Gly-Tyr; Met-enkephalin-Arg-Phe | Query 198 LYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 + ||||||+||+ ||+ # | |||||||+ | | |+ +|| Sbjct 200 IQKRYGGFMRRVGRPEWW#EDYQKRYGGFMTRFTDSFLPSDEDGESYS 246 Query 197 DLYKRYGGFLRRIRPKLK#WDN-----QKRYGGFLRR 227 ++ ||||||+| | # ++ |||||||+|| Sbjct 175 EINKRYGGFMRGYRRSTD#LEDETSGIQKRYGGFMRR 210 |
| Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Tyr; Met-enkephalin-Arg-Phe | Query 198 LYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 + ||||||+||+ ||+ # | |||||||+ | | |+ +|| Sbjct 154 IQKRYGGFMRRVGRPEWW#QDYQKRYGGFMTRFTDSFLPSDEDGESYS 200 Query 197 DLYKRYGGFLRRIRPKLK#WDN-----QKRYGGFLRR 227 ++ ||||||+| | # ++ |||||||+|| Sbjct 129 EMNKRYGGFMRGYRRSTD#LEDETRGIQKRYGGFMRR 164 |
| Roseovarius sp. 217 | Query 201 RYGGFLRRIRPKLK#WDNQKRYGGFLRRQFKVVTRSQ 236 | | |||| +|+++# | |+ | | | + + | |+| Sbjct 99 RTGAFLRRDKPEIE#RDLQQVYDRFPRLRERRVQRAQ 134 |
| synthetic construct | Query 197 DLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 +| ||||||+||+ ||+ # | ||||||||+| | | | +|| Sbjct 205 ELQKRYGGFMRRVGRPEWW#MDYQKRYGGFLKR-FAEALPSDEEGESYS 251 Query 188 QDGDQVGHEDLYKRYGGFLRRIR--PKLK#WDN---QKRYGGFLRR 227 ||| |++ ||||||+| ++ |+|+# + |||||||+|| Sbjct 173 QDGSD-NEEEVSKRYGGFMRGLKRSPQLE#DEAKELQKRYGGFMRR 216 Query 197 DLYKRYGGFLRRIRPKLK#WDNQ------------KRYGGFLR 226 | |||||||+| | # | + ||||||+| Sbjct 225 DYQKRYGGFLKRFAEALP#SDEEGESYSKEVPEMEKRYGGFMR 266 |
| Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | Query 197 DLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYSE 244 +| ||||||+||+ ||+ # | ||||||||+| + + +| | | Sbjct 207 ELQKRYGGFMRRVGRPEWW#MDYQKRYGGFLKRFAESLPSDEEGENYSKE 255 Query 200 KRYGGFLRRIR--PKLK#WDN---QKRYGGFLRR 227 ||||||+| ++ |+|+# + |||||||+|| Sbjct 186 KRYGGFMRSLKRSPQLE#DEAKELQKRYGGFMRR 218 Query 197 DLYKRYGGFLRRIRPKLK#WDNQ------------KRYGGFLR 226 | |||||||+| | # | + ||||||+| Sbjct 227 DYQKRYGGFLKRFAESLP#SDEEGENYSKEVPEIEKRYGGFMR 268 |
| Cricetinae | Query 197 DLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 +| ||||||+||+ ||+ # | ||||||||+| | | | +|| Sbjct 206 ELQKRYGGFMRRVGRPEWW#MDYQKRYGGFLKR-FAESLPSDEEAESYS 252 Query 197 DLYKRYGGFLRRIRPKLK#WDNQ------------KRYGGFLR 226 | |||||||+| | # | + ||||||+| Sbjct 226 DYQKRYGGFLKRFAESLP#SDEEAESYSKEVPEIEKRYGGFMR 267 |
| Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu-enkephalin; Met-enkephalin-Arg-Phe | Query 197 DLYKRYGGFLRRI-RPKLK#WDNQKRYGGFLRRQFKVVTRSQENPNTYS 243 +| ||||||+||+ ||+ # | ||||||||+| | | | +|| Sbjct 207 ELQKRYGGFMRRVGRPEWW#MDYQKRYGGFLKR-FAESLPSDEEGESYS 253 Query 200 KRYGGFLRRIR--PKLK#WDN---QKRYGGFLRR 227 ||||||+| ++ |+|+# + |||||||+|| Sbjct 186 KRYGGFMRGLKRSPQLE#DEAKELQKRYGGFMRR 218 Query 197 DLYKRYGGFLRRIRPKLK#WDNQ------------KRYGGFLR 226 | |||||||+| | # | + ||||||+| Sbjct 227 DYQKRYGGFLKRFAESLP#SDEEGESYSKEVPEMEKRYGGFMR 268 |
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