SB0054 : Glucagon
[ CaMP Format ]
* Basic Information
Organism | Rattus norvegicus (Norway rat) |
Protein Names | glucagon [Rattus norvegicus]; glucagon; glucagon-like peptide-1; Glucagon; Glicentin; Glicentin-related polypeptide; GRPP; Oxyntomodulin; OXM; OXY; Glucagon-like peptide 1; GLP-1; Glucagon-like peptide 1(7-37); GLP-1(7-37); Glucagon-like peptide 1(7-36); GLP-1(7-36); Glucagon-like peptide 2; GLP-2 |
Gene Names | Gcg; glucagon |
Gene Locus | 3q22-q24; chromosome 3 |
GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 180 aa
Average Mass: 20.846 kDa
Monoisotopic Mass: 20.833 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
domain name | begin | end | score | e-value |
---|---|---|---|---|
--- cleavage 67 --- | ||||
--- cleavage 69 --- | ||||
Putative mycoplasma lipoprotein, C-terminal region 1. | 70 | 110 | 19.0 | 0.2 |
--- cleavage 74 (inside Putative mycoplasma lipoprotein, C-terminal region 70..110) --- | ||||
--- cleavage 77 (inside Putative mycoplasma lipoprotein, C-terminal region 70..110) --- | ||||
--- cleavage 79 (inside Putative mycoplasma lipoprotein, C-terminal region 70..110) --- | ||||
Putative mycoplasma lipoprotein, C-terminal region 2. | 112 | 126 | 16.0 | 0.0 |
Putative mycoplasma lipoprotein, C-terminal region 3. | 160 | 177 | 16.0 | 0.1 |
3. Sequence Information
Fasta Sequence: SB0054.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
5 [sites] cleaved by Calpain 1 and 2
Source Reference: [PubMed ID: 6092335] Sasaki T, Kikuchi T, Yumoto N, Yoshimura N, Murachi T, Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates. J Biol Chem. 1984 Oct 25;259(20):12489-94.
Cleavage sites (±10aa)
[Site 1] FTSDYSKYLD67-SRRAQDFVQW
Asp67 Ser
P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
---|---|---|---|---|---|---|---|---|---|
Phe58 | Thr59 | Ser60 | Asp61 | Tyr62 | Ser63 | Lys64 | Tyr65 | Leu66 | Asp67 |
P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
Ser68 | Arg69 | Arg70 | Ala71 | Gln72 | Asp73 | Phe74 | Val75 | Gln76 | Trp77 |
Sequence conservation (by blast) Sequence conservation (by blast)
Reference peptide (cleaved bond±30 residues) |
---|
TEPLEDPDQINEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFER |
Summary
# | organism | max score | hits | top seq |
---|---|---|---|---|
1 | N/A | 79.30 | 44 | 0810207A glucagon 37 |
2 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 63.20 | 1 | glucagon G-33 |
3 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 60.50 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
4 | Contains: Glucagon; Glucagon-like peptide | 59.30 | 3 | GLUC_AMICA Glucagon precursor |
5 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 59.30 | 1 | glucagon II |
6 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 59.30 | 1 | glucagon |
7 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 57.40 | 1 | glucagon G-29 |
8 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.60 | 1 | GLUC_LAMFL Glucagon gi |
9 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 56.20 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gi |
10 | Ambloplites rupestris | 55.50 | 1 | proglucagon |
11 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 52.40 | 1 | glucagon |
12 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 44.70 | 1 | GLUC1_PETMA Glucagon-1 precursor |
13 | Gallus gallus | 43.90 | 3 | glucagon isoform 1 |
14 | Meleagris gallopavo | 43.90 | 2 | preproglucagon B |
15 | Canis familiaris | 43.50 | 3 | PREDICTED: similar to Gastric inhibitory polypept |
16 | Rattus norvegicus | 43.50 | 1 | gastric inhibitory polypeptide |
17 | Homo sapiens | 42.00 | 6 | gastric inhibitory polypeptide preproprotein |
18 | Bos taurus | 42.00 | 2 | PREDICTED: similar to Gastric inhibitory polypept |
19 | Xenopus laevis | 41.20 | 3 | proglucagon I |
20 | Xenopus tropicalis | 41.20 | 1 | glucagon |
21 | Mus musculus | 40.80 | 6 | unnamed protein product |
22 | Mus musculus | 40.80 | 2 | gastric inhibitory polypeptide |
23 | Oncorhynchus tshawytscha | 40.80 | 1 | S78474_1 proglucagon |
24 | Heloderma suspectum | 40.40 | 2 | proglucagon |
25 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 40.00 | 1 | glucagon-like peptide, GLP |
26 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 39.70 | 2 | GLUC_CARAU Glucagon precursor |
27 | Hoplobatrachus rugulosus | 39.70 | 1 | AF324209_1 proglucagon |
28 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 39.70 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
29 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 39.70 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
30 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 38.90 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
31 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 38.90 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
32 | Tetraodon nigroviridis | 38.50 | 3 | unnamed protein product |
33 | Heloderma horridum | 37.70 | 1 | EXE3_HELHO Exendin-3 precursor gi |
34 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 37.00 | 1 | GLUC2_PETMA Glucagon-2 precursor |
35 | Bos taurus | 36.20 | 1 | vasoactive intestinal peptide |
36 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 35.40 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
37 | Danio rerio | 35.00 | 1 | glucagon polyprotein |
38 | Heloderma suspectum, venom, Peptide, 39 aa | 35.00 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30- |
39 | synthetic construct | 35.00 | 1 | Homo sapiens glucagon |
40 | Contains: Glucagon-1; Glucagon-like peptide 1-1 | 34.70 | 1 | GLUC1_ONCKI Glucagon-1 precursor |
41 | Canis lupus familiaris | 34.30 | 1 | glucagon |
42 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 34.30 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
43 | Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | 33.90 | 1 | VIP_MOUSE VIP peptides precursor |
44 | Sus scrofa | 33.90 | 1 | glucagon |
45 | Rattus norvegicus | 33.50 | 4 | glucagon |
46 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 33.50 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gi |
47 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 33.50 | 1 | GLUC_LEPSP Glucagon precursor |
48 | Arvicanthis ansorgei | 32.70 | 1 | vasoactive intestinal polypeptide |
49 | swine, intestines, Peptide Partial, 56 aa | 30.80 | 1 | secretin precursor, N-prosecretin, secretin-(-9 t |
50 | swine, small intestine, Peptide Partial, 36 aa | 29.60 | 1 | diazepam-binding inhibitor (32-86), DBI(32-86)=an |
Top-ranked sequences
organism | matching |
---|---|
N/A | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIA 89 |||||||||||||||#|||||||||||||||||+|||| Sbjct 1 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNKNNIA 37 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN 84 ||+||||||||||+|#+|||+|||||||+|||| Sbjct 1 HSEGTFTSDYSKYMD#NRRAKDFVQWLMSTKRN 32 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 81 |||||||||||||||#+||||||+||||+| Sbjct 1 HSQGTFTSDYSKYLD#NRRAQDFIQWLMST 29 |
Contains: Glucagon; Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 81 |||||||+|||||+|#+|||||||||||+| Sbjct 1 HSQGTFTNDYSKYMD#TRRAQDFVQWLMST 29 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN 84 ||+|||++||||||+#+|||||||||| |+||| Sbjct 1 HSEGTFSNDYSKYLE#TRRAQDFVQWLKNSKRN 32 |
Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 81 |||||||+|||||+|#+|||||||||||+| Sbjct 1 HSQGTFTNDYSKYMD#TRRAQDFVQWLMST 29 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 81 ||+||||||||||+|#+|||+|||||||+| Sbjct 1 HSEGTFTSDYSKYMD#NRRAKDFVQWLMST 29 |
Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 81 ||||+||||||||||#|++|+||| ||||| Sbjct 1 HSQGSFTSDYSKYLD#SKQAKDFVIWLMNT 29 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN 84 ||+|||++||||||+# |+|||||+|||| ||+ Sbjct 1 HSEGTFSNDYSKYLE#DRKAQDFVRWLMNNKRS 32 |
Ambloplites rupestris | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 92 |||||||+||+ ||+# |+||||++|||| ||+ ||| Sbjct 1 HSQGTFTNDYTNYLE#DRQAQDFIRWLMNNKRS-GAAEKRH 39 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 81 ||+|||||||||||+#+++|+|||+|||| Sbjct 1 HSEGTFTSDYSKYLE#NKQAKDFVRWLMNA 29 |
Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 92 ||||+|||||||||||+#+++|+|||+|||| || + + +|| Sbjct 41 KRHSEGTFTSDYSKYLE#NKQAKDFVRWLMNAKRGGSELQRRH 82 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 85 +||+ ||||+| + |||#++ |+||| || + ++| Sbjct 80 RRHADGTFTNDMTSYLD#AKAARDFVSWLARSDKSR 114 |
Gallus gallus | Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN------------- 84 +|||++ |+|| |||||||||||||||||#||||||||||||+|||| Sbjct 40 SEPLDESRQLNEVKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMSTKRNGQQGQEDKENDKF 99 Query 85 -----RNNIAKRHDEFER 97 | |+||| |||| Sbjct 100 PDQLSSNAISKRHSEFER 117 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNI 88 +||+ |||||| +| ||# |++|++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILD#DMAAKEFLKWLINTKVTQRDL 201 Query 44 PDQIN---------EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 86 |||++ | +||++||+||| + ||+# + |++|+ ||+| + |+ Sbjct 100 PDQLSSNAISKRHSEFERHAEGTYTSDITSYLE#GQAAKEFIAWLVNGRGRRD 151 |
Meleagris gallopavo | Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN------------- 84 +|||++ |+|| |||||||||||||||||#||||||||||||+|||| Sbjct 40 SEPLDESRQLNEVKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMSTKRNGQQGQEDKENDEF 99 Query 85 -----RNNIAKRHDEFER 97 | |+||| |||| Sbjct 100 PDQLSSNAISKRHSEFER 117 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNI 88 +||+ |||||| +| ||# |++|++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILD#DMAAKEFLKWLINTKVTQRDL 201 Query 42 EDPDQIN---------EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 86 | |||++ | +||++||+||| + ||+# + |++|+ ||+| + |+ Sbjct 98 EFPDQLSSNAISKRHSEFERHAEGTYTSDITSYLE#GQAAKEFIAWLVNGRGRRD 151 |
Canis familiaris | Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN----NIAKR 91 |+++||| |||| +|# | |||| ||+ | +| || +| Sbjct 43 RYAEGTFISDYSIAMD#KIRQQDFVNWLLAQKGKKNDWKHNITQR 86 |
Rattus norvegicus | Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNN 87 |+++||| |||| +|# | |||| ||+ | +|+ Sbjct 43 RYAEGTFISDYSIAMD#KIRQQDFVNWLLAQKGKKND 78 |
Homo sapiens | Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN----NIAKR 91 |+++||| |||| +|# |||| ||+ | +| || +| Sbjct 51 RYAEGTFISDYSIAMD#KIHQQDFVNWLLAQKGKKNDWKHNITQR 94 |
Bos taurus | Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN----NIAKR 91 |+++||| |||| +|# | |||| ||+ | ++ || +| Sbjct 81 RYAEGTFISDYSIAMD#KIRQQDFVNWLLAQKGKKSDWIHNITQR 124 |
Xenopus laevis | Query 39 EPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 | ++| +|+ | |||||||||||||||||#||||||||||||||||+ +++|+ ++|| Sbjct 39 EAVDDSEQLKEVKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRS-GELSRRNADYER 96 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 +||++|||||| ++ ||# + |++|+ ||+| ++ |++|+ |||| Sbjct 95 ERHAEGTFTSDVTQQLD#EKAAKEFIDWLINGGPSKEIISRRNAEFER 141 Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 86 ||++||||+| + ||+# + |++|| ||+ + || Sbjct 179 RHAEGTFTNDMTNYLE#EKAAKEFVGWLIKGRPKRN 213 Query 50 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 |+||+ |+||+| +| ||# ||+|+ |++||+ Sbjct 224 DRRHADGSFTNDINKVLD#IIAAQEFLDWVINTQ 256 Query 49 EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 | +||++||+|+| ++||+# + |++|++||+ | Sbjct 138 EFERHAEGTYTNDVTEYLE#EKAAKEFIEWLIKGK 171 |
Xenopus tropicalis | Query 39 EPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 | ++| |+ | |||||||||||||||||#|||||||+||||||||+ +++|+ ++|| Sbjct 39 EAVDDSQQLKEVKRHSQGTFTSDYSKYLD#SRRAQDFIQWLMNTKRS-GGLSRRNADYER 96 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 +||++|||||| +++||# + |++|+ ||+| ++ |++|+ + || Sbjct 95 ERHAEGTFTSDVTQHLD#EKAAKEFIDWLINGGPSKEIISRRNADVER 141 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 +||++||+|+| ++||+# + |++|++||+| | Sbjct 140 ERHAEGTYTNDVTEYLE#EKAAKEFIEWLINGK 171 Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 86 ||++||||+| + ||+# + |++|| ||+ + || Sbjct 179 RHAEGTFTNDMTNYLE#EKAAKEFVGWLIKGRPKRN 213 Query 50 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 |+||+ |+||+| +| ||# ||+|+ |++||+ Sbjct 224 DRRHADGSFTNDINKVLD#IIAAQEFLDWVINTQ 256 |
Mus musculus | Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN----NIAKR 91 |+++||| |||| +|# | |||| ||+ + ++ || +| Sbjct 29 RYAEGTFISDYSIAMD#KIRQQDFVNWLLAQRGKKSDWKHNITQR 72 |
Mus musculus | Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN----NIAKR 91 |+++||| |||| +|# | |||| ||+ + ++ || +| Sbjct 43 RYAEGTFISDYSIAMD#KIRQQDFVNWLLAQRGKKSDWKHNITQR 86 |
Oncorhynchus tshawytscha | Query 54 SQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 92 | |||++||||| +# | ||||||||||+||+ +||| Sbjct 2 SXGTFSNDYSKYQE#ERMAQDFVQWLMNSKRS-GAPSKRH 39 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 85 |||+ ||+||| | || # + |+||| || + + | Sbjct 37 KRHADGTYTSDVSTYLQ#DQAAKDFVSWLKSGRARR 71 |
Heloderma suspectum | Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKR-------------- 83 |||+| |+|| |||||||||||||||||#+||||||||||||||| Sbjct 38 AEPLDDSRQLNEVKRHSQGTFTSDYSKYLD#TRRAQDFVQWLMNTKRSGQQGVEEREKENL 97 Query 84 ----NRNNIAKRHDEFER 97 + | +|+ | |+|| Sbjct 98 LDQLSSNGLARHHAEYER 115 Query 49 EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 85 | +||+ | +||| | ||+# + |++|+ ||+| + | Sbjct 112 EYERHADGRYTSDISSYLE#GQAAKEFIAWLVNGRGRR 148 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWL 78 |+ ||||+| + |||#++ |+||| || Sbjct 1 HADGTFTNDMTSYLD#AKAARDFVSWL 26 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 94 ||||+|||++||||||+#+|||||||+||||+| | + |||| | Sbjct 48 KRHSEGTFSNDYSKYLE#TRRAQDFVEWLMNSKSNGGS-AKRHAE 90 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWL 78 |||++||+||| | +| # + ||+|| || Sbjct 86 KRHAEGTYTSDISSFLR#DQAAQNFVAWL 113 |
Hoplobatrachus rugulosus | Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 || |+| | || |||||||||||||||||#|||||||||||||+||+ |+||+ +||| Sbjct 38 TEALDDSDHHNEVKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNSKRS-GGISKRNVQFER 96 Query 50 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 81 |+||+ |+||||++| ||# + ||+|+ |++|| Sbjct 178 DRRHADGSFTSDFNKALD#IKAAQEFLDWIINT 209 Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 86 ||++|||||| + ||+# + |++|| ||+ + || Sbjct 134 RHAEGTFTSDMTSYLE#EKAAKEFVDWLIKGRPKRN 168 Query 52 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 94 ||++||+|+| +++|+# + |++|+ ||+ | + ++ || | Sbjct 96 RHAEGTYTNDVTQFLE#EKAAKEFIDWLIKGKPKKQRLS-RHAE 137 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 |+ |+|||| +| ||#+ |++|+ ||++|| Sbjct 1 HADGSFTSDINKVLD#TIAAKEFLNWLISTK 30 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 92 |||+| + ||||+|||++||||||+#+|||||||||| |+| || + +|| Sbjct 41 TEPIEPLNM----KRHSEGTFSNDYSKYLE#TRRAQDFVQWLKNSK--RNGLFRRH 89 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWL 78 +||+ ||+||| | || # + |+||| || Sbjct 87 RRHADGTYTSDVSSYLQ#DQAAKDFVSWL 114 |
Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 41 LEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 92 ||| + || |+|||++ |||| +# | |+||+ ||||+||+ +||| Sbjct 40 LEDLRGVPNMKRQSEGTFSNYYSKYQE#ERMARDFLHWLMNSKRS-GAPSKRH 90 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWL 78 |||+ ||+||| | || # + |+||| || Sbjct 88 KRHADGTYTSDVSTYLQ#DQAAKDFVSWL 115 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 +|| |+|||| +| ||#| |++++ |+| +| Sbjct 135 RRHVDGSFTSDVNKVLD#SLAAKEYLLWVMTSK 166 |
Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 38 TEPL-EDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 92 |+|| || ++ ||||+|||++||||| +# | ||||||||||+||+ +||| Sbjct 36 TDPLLEDLMGVSNVKRHSEGTFSNDYSKYQE#ERMAQDFVQWLMNSKRS-GAPSKRH 90 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 85 |||+ ||+||| | || # + |+||| || + + | Sbjct 88 KRHADGTYTSDVSTYLQ#DQAAKDFVSWLKSGRARR 122 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 +|| |+|||| +| ||#| |++++ |+| +| Sbjct 135 RRHVDGSFTSDVNKVLD#SLAAKEYLLWVMTSK 166 |
Tetraodon nigroviridis | Query 41 LEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 92 | +| ++ ||||+|||++||||||+#+|||||||||| |+||| ++ +|| Sbjct 777 LTEPSDLSNMKRHSEGTFSNDYSKYLE#TRRAQDFVQWLKNSKRN-GSLFRRH 827 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 85 +||+ ||+||| | || # + |++|| || | | | Sbjct 825 RRHADGTYTSDVSAYLQ#DQAAKEFVSWL-KTGRGR 858 |
Heloderma horridum | Query 48 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMN 80 ++ |||| |||||| || ++# + |++|| | Sbjct 43 SKIKRHSDGTFTSDLSKQME#EEAVRLFIEWLKN 75 |
Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 46 QINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKR------NRNNIAKRHDE 94 +|+ |||||+|||||||+||# ++|+||| ||+|||| |+ ||| + Sbjct 37 EISLANRHSQGSFTSDYSKHLD#VKQAKDFVTWLLNTKRRGVDAQAGANLEKRHSD 91 Query 48 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWL 78 | +|||| |+||+| + ||# |++|++|| Sbjct 84 NLEKRHSDGSFTNDMNVMLD#RMSAKNFLEWL 114 |
Bos taurus | Query 47 INEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 ++ + ||+ | ||||||+ | # |+ +++ |+ || |+|++ +| Sbjct 75 VSRNVRHADGVFTSDYSRLLG#QLSAKKYLESLIG-KRVSNSISEDQGPIKR 124 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 42 EDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIA-KRH 92 ++| +++ ||||+|||++||||||+# |+||+||+|||| | |+ +| ||| Sbjct 42 DEPRELSNMKRHSEGTFSNDYSKYLE#DRKAQEFVRWLMNNK--RSGVAEKRH 91 Query 50 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWL 78 +|||+ |||||| | || # + +||| | Sbjct 88 EKRHADGTFTSDVSSYLK#DQAIKDFVDRL 116 |
Danio rerio | Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 94 ||||+|||++||||||+#+|||||||||||| ||| ++ ||| | Sbjct 48 KRHSEGTFSNDYSKYLE#TRRAQDFVQWLMNAKRNGGSV-KRHAE 90 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWL 78 |||++||+||| | || # + || || | Sbjct 86 KRHAEGTYTSDVSSYLQ#DQAAQRFVARL 113 |
Heloderma suspectum, venom, Peptide, 39 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMN 80 | +|||||| || ++# + |++|| | Sbjct 1 HGEGTFTSDLSKQME#EEAVRLFIEWLKN 28 |
synthetic construct | Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 +|| ||||+||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 38 ADPLSDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 +||+ |+|+ + + ||#+ |+||+ ||+ || Sbjct 144 RRHADGSFSDEMNTILD#NLAARDFINWLIQTK 175 |
Contains: Glucagon-1; Glucagon-like peptide 1-1 | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 81 ||+|||++||||| +# | ||||||||||+ Sbjct 1 HSEGTFSNDYSKYQE#ERMAQDFVQWLMNS 29 Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWL 78 |+ ||+||+ | || # + |+||| || Sbjct 38 HADGTYTSNVSTYLQ#DQAAKDFVSWL 63 |
Canis lupus familiaris | Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 |||| | ||+||||||||||||||||||||#|||||||||||||||||+|||||||||||| Sbjct 38 TEPLNDLDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNKNNIAKRHDEFER 97 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 +||+ |+|+ + + ||#+ +||+ ||+ || Sbjct 144 RRHADGSFSDEMNTVLD#TLATRDFINWLLQTK 175 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 85 |+ || ||| | +|+# + ++|+ ||++ + | Sbjct 1 HADGTLTSDISSFLE#KQATKEFIAWLVSGRGRR 33 |
Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | Query 47 INEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIA------KRHDE 94 ++ + ||+ | ||||||+ | # |+ +++ |+ || ++|+ ||| + Sbjct 75 VSRNARHADGVFTSDYSRLLG#QISAKKYLESLIG-KRISSSISEDPVPIKRHSD 127 |
Sus scrofa | Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 |+||+||||+ |||||||||||||||||||#|||||||||||||||||+|||||||||||| Sbjct 38 TDPLDDPDQMTEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNKNNIAKRHDEFER 97 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 +||+ |+|+ + + ||#+ +||+ ||++|| Sbjct 144 RRHADGSFSDEMNTVLD#NLATRDFINWLLHTK 175 |
Rattus norvegicus | Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 38 TEPLEDPDQINEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 Query 51 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 82 +||+ |+|+ + + ||#+ +||+ ||+ || Sbjct 144 RRHADGSFSDEMNTILD#NLATRDFINWLIQTK 175 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 56 GTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 85 ||+||| | || # + |++|| || | | | Sbjct 3 GTYTSDVSSYLQ#DQAAKEFVSWL-KTGRGR 31 |
Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN 84 |||||||+|||||||#+|||||||||||+|||+ Sbjct 1 HSQGTFTNDYSKYLD#TRRAQDFVQWLMSTKRS 32 Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWL 78 |+ ||+||| | || # + |+ || || Sbjct 45 HADGTYTSDVSSYLQ#DQAAKKFVTWL 70 |
Arvicanthis ansorgei | Query 47 INEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNI------AKRHDE 94 ++ + ||+ | ||||||+ | # |+ +++ |+ || ++| ||| + Sbjct 58 VSRNARHADGVFTSDYSRLLG#QISAKKYLESLIG-KRISSSILEDPVPIKRHSD 110 |
swine, intestines, Peptide Partial, 56 aa | Query 53 HSQGTFTSDYSKYLD#SRRAQDFVQWLM 79 || |||||+ |+ |#| | | +| |+ Sbjct 30 HSDGTFTSELSRLRD#SARLQRLLQGLV 56 |
swine, small intestine, Peptide Partial, 36 aa | Query 59 TSDYSKYLD#SRRAQDFVQWLMNTKRNRNN 87 |||| +|# | |||| ||+ | +++ Sbjct 1 ISDYSIAMD#KIRQQDFVNWLLAQKGKKSD 29 |
[Site 2] SDYSKYLDSR69-RAQDFVQWLM
Arg69 Arg
P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
---|---|---|---|---|---|---|---|---|---|
Ser60 | Asp61 | Tyr62 | Ser63 | Lys64 | Tyr65 | Leu66 | Asp67 | Ser68 | Arg69 |
P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
Arg70 | Ala71 | Gln72 | Asp73 | Phe74 | Val75 | Gln76 | Trp77 | Leu78 | Met79 |
Sequence conservation (by blast) Sequence conservation (by blast)
Reference peptide (cleaved bond±30 residues) |
---|
PLEDPDQINEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHA |
Summary
# | organism | max score | hits | top seq |
---|---|---|---|---|
1 | N/A | 79.00 | 44 | 0810207A glucagon 37 |
2 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 63.20 | 1 | glucagon G-33 |
3 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 60.50 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
4 | Contains: Glucagon; Glucagon-like peptide | 59.30 | 3 | GLUC_AMICA Glucagon precursor |
5 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 59.30 | 1 | glucagon II |
6 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 58.90 | 1 | glucagon |
7 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 57.40 | 1 | glucagon G-29 |
8 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.60 | 1 | GLUC_LAMFL Glucagon gi |
9 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 55.80 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gi |
10 | Ambloplites rupestris | 55.50 | 1 | proglucagon |
11 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 52.40 | 1 | glucagon |
12 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 44.30 | 1 | GLUC1_PETMA Glucagon-1 precursor |
13 | Gallus gallus | 43.90 | 3 | glucagon isoform 1 |
14 | Meleagris gallopavo | 43.90 | 2 | preproglucagon B |
15 | Canis familiaris | 43.50 | 3 | PREDICTED: similar to Gastric inhibitory polypept |
16 | Rattus norvegicus | 43.50 | 1 | gastric inhibitory polypeptide |
17 | Bos taurus | 42.00 | 2 | PREDICTED: similar to Gastric inhibitory polypept |
18 | Homo sapiens | 41.60 | 6 | gastric inhibitory polypeptide preproprotein |
19 | Xenopus laevis | 41.20 | 3 | proglucagon I |
20 | Xenopus tropicalis | 41.20 | 1 | glucagon |
21 | Mus musculus | 40.80 | 6 | unnamed protein product |
22 | Mus musculus | 40.80 | 2 | gastric inhibitory polypeptide |
23 | Oncorhynchus tshawytscha | 40.80 | 1 | S78474_1 proglucagon |
24 | Heloderma suspectum | 40.00 | 2 | proglucagon |
25 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 39.70 | 2 | GLUC_CARAU Glucagon precursor |
26 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 39.70 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
27 | Hoplobatrachus rugulosus | 39.70 | 1 | AF324209_1 proglucagon |
28 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 39.70 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
29 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 39.70 | 1 | glucagon-like peptide, GLP |
30 | Bos taurus | 39.30 | 1 | vasoactive intestinal peptide |
31 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 38.90 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
32 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 38.90 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
33 | Tetraodon nigroviridis | 38.50 | 3 | unnamed protein product |
34 | Heloderma horridum | 37.70 | 1 | EXE3_HELHO Exendin-3 precursor gi |
35 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 37.00 | 1 | GLUC2_PETMA Glucagon-2 precursor |
36 | Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | 36.20 | 1 | VIP_MOUSE VIP peptides precursor |
37 | Rattus norvegicus | 35.80 | 4 | PREDICTED: similar to VIP peptides precursor |
38 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 35.40 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
39 | Arvicanthis ansorgei | 35.00 | 1 | vasoactive intestinal polypeptide |
40 | Danio rerio | 35.00 | 1 | glucagon polyprotein |
41 | Heloderma suspectum, venom, Peptide, 39 aa | 35.00 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30- |
42 | synthetic construct | 35.00 | 1 | Homo sapiens glucagon |
43 | Contains: Glucagon-1; Glucagon-like peptide 1-1 | 34.70 | 1 | GLUC1_ONCKI Glucagon-1 precursor |
44 | Canis lupus familiaris | 34.30 | 1 | glucagon |
45 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 34.30 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
46 | Sus scrofa | 33.90 | 1 | glucagon |
47 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 33.50 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gi |
48 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 33.50 | 1 | GLUC_LEPSP Glucagon precursor |
49 | swine, intestines, Peptide Partial, 56 aa | 30.80 | 1 | secretin precursor, N-prosecretin, secretin-(-9 t |
50 | swine, small intestine, Peptide Partial, 36 aa | 29.60 | 1 | diazepam-binding inhibitor (32-86), DBI(32-86)=an |
Top-ranked sequences
organism | matching |
---|---|
N/A | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIA 89 |||||||||||||||||#|||||||||||||||+|||| Sbjct 1 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNKNNIA 37 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN 84 ||+||||||||||+|+|#||+|||||||+|||| Sbjct 1 HSEGTFTSDYSKYMDNR#RAKDFVQWLMSTKRN 32 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 81 |||||||||||||||+|#|||||+||||+| Sbjct 1 HSQGTFTSDYSKYLDNR#RAQDFIQWLMST 29 |
Contains: Glucagon; Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 81 |||||||+|||||+|+|#||||||||||+| Sbjct 1 HSQGTFTNDYSKYMDTR#RAQDFVQWLMST 29 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN 84 ||+|||++||||||++|#||||||||| |+||| Sbjct 1 HSEGTFSNDYSKYLETR#RAQDFVQWLKNSKRN 32 |
Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 81 |||||||+|||||+|+|#||||||||||+| Sbjct 1 HSQGTFTNDYSKYMDTR#RAQDFVQWLMST 29 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 81 ||+||||||||||+|+|#||+|||||||+| Sbjct 1 HSEGTFTSDYSKYMDNR#RAKDFVQWLMST 29 |
Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 81 ||||+|||||||||||+#+|+||| ||||| Sbjct 1 HSQGSFTSDYSKYLDSK#QAKDFVIWLMNT 29 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN 84 ||+|||++||||||+ |#+|||||+|||| ||+ Sbjct 1 HSEGTFSNDYSKYLEDR#KAQDFVRWLMNNKRS 32 |
Ambloplites rupestris | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 92 |||||||+||+ ||+ |#+||||++|||| ||+ ||| Sbjct 1 HSQGTFTNDYTNYLEDR#QAQDFIRWLMNNKRS-GAAEKRH 39 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 81 ||+|||||||||||+++#+|+|||+|||| Sbjct 1 HSEGTFTSDYSKYLENK#QAKDFVRWLMNA 29 |
Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 92 ||||+|||||||||||+++#+|+|||+|||| || + + +|| Sbjct 41 KRHSEGTFTSDYSKYLENK#QAKDFVRWLMNAKRGGSELQRRH 82 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 85 +||+ ||||+| + |||++# |+||| || + ++| Sbjct 80 RRHADGTFTNDMTSYLDAK#AARDFVSWLARSDKSR 114 |
Gallus gallus | Query 40 PLEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN--------------- 84 ||++ |+|| |||||||||||||||||||#||||||||||+|||| Sbjct 42 PLDESRQLNEVKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMSTKRNGQQGQEDKENDKFPD 101 Query 85 ---RNNIAKRHDEFERHA 99 | |+||| |||||| Sbjct 102 QLSSNAISKRHSEFERHA 119 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNI 88 +||+ |||||| +| || # |++|++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDM#AAKEFLKWLINTKVTQRDL 201 Query 44 PDQIN---------EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 86 |||++ | +||++||+||| + ||+ +# |++|+ ||+| + |+ Sbjct 100 PDQLSSNAISKRHSEFERHAEGTYTSDITSYLEGQ#AAKEFIAWLVNGRGRRD 151 |
Meleagris gallopavo | Query 40 PLEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN--------------- 84 ||++ |+|| |||||||||||||||||||#||||||||||+|||| Sbjct 42 PLDESRQLNEVKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMSTKRNGQQGQEDKENDEFPD 101 Query 85 ---RNNIAKRHDEFERHA 99 | |+||| |||||| Sbjct 102 QLSSNAISKRHSEFERHA 119 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNI 88 +||+ |||||| +| || # |++|++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDM#AAKEFLKWLINTKVTQRDL 201 Query 42 EDPDQIN---------EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 86 | |||++ | +||++||+||| + ||+ +# |++|+ ||+| + |+ Sbjct 98 EFPDQLSSNAISKRHSEFERHAEGTYTSDITSYLEGQ#AAKEFIAWLVNGRGRRD 151 |
Canis familiaris | Query 52 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN----NIAKR 91 |+++||| |||| +| #| |||| ||+ | +| || +| Sbjct 43 RYAEGTFISDYSIAMDKI#RQQDFVNWLLAQKGKKNDWKHNITQR 86 |
Rattus norvegicus | Query 52 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNN 87 |+++||| |||| +| #| |||| ||+ | +|+ Sbjct 43 RYAEGTFISDYSIAMDKI#RQQDFVNWLLAQKGKKND 78 |
Bos taurus | Query 52 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN----NIAKR 91 |+++||| |||| +| #| |||| ||+ | ++ || +| Sbjct 81 RYAEGTFISDYSIAMDKI#RQQDFVNWLLAQKGKKSDWIHNITQR 124 |
Homo sapiens | Query 52 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN----NIAKR 91 |+++||| |||| +| # |||| ||+ | +| || +| Sbjct 51 RYAEGTFISDYSIAMDKI#HQQDFVNWLLAQKGKKNDWKHNITQR 94 |
Xenopus laevis | Query 40 PLEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 ++| +|+ | |||||||||||||||||||#||||||||||||||+ +++|+ ++|||| Sbjct 40 AVDDSEQLKEVKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRS-GELSRRNADYERHA 98 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 +||++|||||| ++ || +# |++|+ ||+| ++ |++|+ |||||| Sbjct 95 ERHAEGTFTSDVTQQLDEK#AAKEFIDWLINGGPSKEIISRRNAEFERHA 143 Query 52 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 86 ||++||||+| + ||+ +# |++|| ||+ + || Sbjct 179 RHAEGTFTNDMTNYLEEK#AAKEFVGWLIKGRPKRN 213 Query 50 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNI 88 |+||+ |+||+| +| || # ||+|+ |++||+ ++ Sbjct 224 DRRHADGSFTNDINKVLDII#AAQEFLDWVINTQETERDL 262 Query 49 EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 82 | +||++||+|+| ++||+ +# |++|++||+ | Sbjct 138 EFERHAEGTYTNDVTEYLEEK#AAKEFIEWLIKGK 171 |
Xenopus tropicalis | Query 40 PLEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 ++| |+ | |||||||||||||||||||#|||||+||||||||+ +++|+ ++|||| Sbjct 40 AVDDSQQLKEVKRHSQGTFTSDYSKYLDSR#RAQDFIQWLMNTKRS-GGLSRRNADYERHA 98 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 +||++|||||| +++|| +# |++|+ ||+| ++ |++|+ + |||| Sbjct 95 ERHAEGTFTSDVTQHLDEK#AAKEFIDWLINGGPSKEIISRRNADVERHA 143 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 82 +||++||+|+| ++||+ +# |++|++||+| | Sbjct 140 ERHAEGTYTNDVTEYLEEK#AAKEFIEWLINGK 171 Query 52 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 86 ||++||||+| + ||+ +# |++|| ||+ + || Sbjct 179 RHAEGTFTNDMTNYLEEK#AAKEFVGWLIKGRPKRN 213 Query 50 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 82 |+||+ |+||+| +| || # ||+|+ |++||+ Sbjct 224 DRRHADGSFTNDINKVLDII#AAQEFLDWVINTQ 256 |
Mus musculus | Query 52 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN----NIAKRH 92 |+++||| |||| +| #| |||| ||+ + ++ || +| Sbjct 29 RYAEGTFISDYSIAMDKI#RQQDFVNWLLAQRGKKSDWKHNITQRE 73 |
Mus musculus | Query 52 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN----NIAKRH 92 |+++||| |||| +| #| |||| ||+ + ++ || +| Sbjct 43 RYAEGTFISDYSIAMDKI#RQQDFVNWLLAQRGKKSDWKHNITQRE 87 |
Oncorhynchus tshawytscha | Query 54 SQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 92 | |||++||||| + |# ||||||||||+||+ +||| Sbjct 2 SXGTFSNDYSKYQEER#MAQDFVQWLMNSKRS-GAPSKRH 39 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 85 |||+ ||+||| | || +# |+||| || + + | Sbjct 37 KRHADGTYTSDVSTYLQDQ#AAKDFVSWLKSGRARR 71 |
Heloderma suspectum | Query 40 PLEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKR---------------- 83 ||+| |+|| |||||||||||||||||+|#|||||||||||||| Sbjct 40 PLDDSRQLNEVKRHSQGTFTSDYSKYLDTR#RAQDFVQWLMNTKRSGQQGVEEREKENLLD 99 Query 84 --NRNNIAKRHDEFERHA 99 + | +|+ | |+|||| Sbjct 100 QLSSNGLARHHAEYERHA 117 Query 49 EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 85 | +||+ | +||| | ||+ +# |++|+ ||+| + | Sbjct 112 EYERHADGRYTSDISSYLEGQ#AAKEFIAWLVNGRGRR 148 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 94 ||||+|||++||||||++|#||||||+||||+| | + |||| | Sbjct 48 KRHSEGTFSNDYSKYLETR#RAQDFVEWLMNSKSNGGS-AKRHAE 90 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWL 78 |||++||+||| | +| +# ||+|| || Sbjct 86 KRHAEGTYTSDISSFLRDQ#AAQNFVAWL 113 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 82 |+ |+|||| +| ||+ # |++|+ ||++|| Sbjct 1 HADGSFTSDINKVLDTI#AAKEFLNWLISTK 30 |
Hoplobatrachus rugulosus | Query 40 PLEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 |+| | || |||||||||||||||||||#|||||||||||+||+ |+||+ +||||| Sbjct 40 ALDDSDHHNEVKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNSKRS-GGISKRNVQFERHA 98 Query 50 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 81 |+||+ |+||||++| || +# ||+|+ |++|| Sbjct 178 DRRHADGSFTSDFNKALDIK#AAQEFLDWIINT 209 Query 52 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 86 ||++|||||| + ||+ +# |++|| ||+ + || Sbjct 134 RHAEGTFTSDMTSYLEEK#AAKEFVDWLIKGRPKRN 168 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 94 +||++||+|+| +++|+ +# |++|+ ||+ | + ++ || | Sbjct 95 ERHAEGTYTNDVTQFLEEK#AAKEFIDWLIKGKPKKQRLS-RHAE 137 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 41 LEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 92 | +| + ||||+|||++||||||++|#||||||||| |+| || + +|| Sbjct 40 LTEPIEPLNMKRHSEGTFSNDYSKYLETR#RAQDFVQWLKNSK--RNGLFRRH 89 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWL 78 +||+ ||+||| | || +# |+||| || Sbjct 87 RRHADGTYTSDVSSYLQDQ#AAKDFVSWL 114 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWL 78 |+ ||||+| + |||++# |+||| || Sbjct 1 HADGTFTNDMTSYLDAK#AARDFVSWL 26 |
Bos taurus | Query 47 INEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 ++ + ||+ | ||||||+ | # |+ +++ |+ || |+|++ +||+ Sbjct 75 VSRNVRHADGVFTSDYSRLLGQL#SAKKYLESLIG-KRVSNSISEDQGPIKRHS 126 |
Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 41 LEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 92 ||| + || |+|||++ |||| + |# |+||+ ||||+||+ +||| Sbjct 40 LEDLRGVPNMKRQSEGTFSNYYSKYQEER#MARDFLHWLMNSKRS-GAPSKRH 90 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWL 78 |||+ ||+||| | || +# |+||| || Sbjct 88 KRHADGTYTSDVSTYLQDQ#AAKDFVSWL 115 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 82 +|| |+|||| +| ||| # |++++ |+| +| Sbjct 135 RRHVDGSFTSDVNKVLDSL#AAKEYLLWVMTSK 166 |
Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 41 LEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 92 ||| ++ ||||+|||++||||| + |# ||||||||||+||+ +||| Sbjct 40 LEDLMGVSNVKRHSEGTFSNDYSKYQEER#MAQDFVQWLMNSKRS-GAPSKRH 90 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNN 87 |||+ ||+||| | || +# |+||| || + + | + Sbjct 88 KRHADGTYTSDVSTYLQDQ#AAKDFVSWLKSGRARRES 124 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 82 +|| |+|||| +| ||| # |++++ |+| +| Sbjct 135 RRHVDGSFTSDVNKVLDSL#AAKEYLLWVMTSK 166 |
Tetraodon nigroviridis | Query 41 LEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 92 | +| ++ ||||+|||++||||||++|#||||||||| |+||| ++ +|| Sbjct 777 LTEPSDLSNMKRHSEGTFSNDYSKYLETR#RAQDFVQWLKNSKRN-GSLFRRH 827 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 85 +||+ ||+||| | || +# |++|| || | | | Sbjct 825 RRHADGTYTSDVSAYLQDQ#AAKEFVSWL-KTGRGR 858 |
Heloderma horridum | Query 48 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMN 80 ++ |||| |||||| || ++ # + |++|| | Sbjct 43 SKIKRHSDGTFTSDLSKQMEEE#AVRLFIEWLKN 75 |
Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 46 QINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKR------NRNNIAKRHDE 94 +|+ |||||+|||||||+|| +#+|+||| ||+|||| |+ ||| + Sbjct 37 EISLANRHSQGSFTSDYSKHLDVK#QAKDFVTWLLNTKRRGVDAQAGANLEKRHSD 91 Query 48 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWL 78 | +|||| |+||+| + || # |++|++|| Sbjct 84 NLEKRHSDGSFTNDMNVMLDRM#SAKNFLEWL 114 |
Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | Query 47 INEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 ++ + ||+ | ||||||+ | # |+ +++ |+ || ++|++ +||+ Sbjct 75 VSRNARHADGVFTSDYSRLLGQI#SAKKYLESLIG-KRISSSISEDPVPIKRHS 126 |
Rattus norvegicus | Query 47 INEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 ++ + ||+ | ||||||+ | # |+ +++ |+ || ++|++ +||+ Sbjct 75 VSRNARHADGVFTSDYSRLLGQI#SAKKYLESLIG-KRISSSISEDPVPVKRHS 126 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 42 EDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIA-KRH 92 ++| +++ ||||+|||++||||||+ |#+||+||+|||| | |+ +| ||| Sbjct 42 DEPRELSNMKRHSEGTFSNDYSKYLEDR#KAQEFVRWLMNNK--RSGVAEKRH 91 Query 50 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWL 78 +|||+ |||||| | || +# +||| | Sbjct 88 EKRHADGTFTSDVSSYLKDQ#AIKDFVDRL 116 |
Arvicanthis ansorgei | Query 47 INEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 ++ + ||+ | ||||||+ | # |+ +++ |+ || ++| + +||+ Sbjct 58 VSRNARHADGVFTSDYSRLLGQI#SAKKYLESLIG-KRISSSILEDPVPIKRHS 109 |
Danio rerio | Query 47 INEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 94 + ||||+|||++||||||++|#||||||||||| ||| ++ ||| | Sbjct 44 LTTMKRHSEGTFSNDYSKYLETR#RAQDFVQWLMNAKRNGGSV-KRHAE 90 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWL 78 |||++||+||| | || +# || || | Sbjct 86 KRHAEGTYTSDVSSYLQDQ#AAQRFVARL 113 |
Heloderma suspectum, venom, Peptide, 39 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMN 80 | +|||||| || ++ # + |++|| | Sbjct 1 HGEGTFTSDLSKQMEEE#AVRLFIEWLKN 28 |
synthetic construct | Query 40 PLEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 || ||||+||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 40 PLSDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 82 +||+ |+|+ + + ||+ # |+||+ ||+ || Sbjct 144 RRHADGSFSDEMNTILDNL#AARDFINWLIQTK 175 |
Contains: Glucagon-1; Glucagon-like peptide 1-1 | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 81 ||+|||++||||| + |# ||||||||||+ Sbjct 1 HSEGTFSNDYSKYQEER#MAQDFVQWLMNS 29 Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWL 78 |+ ||+||+ | || +# |+||| || Sbjct 38 HADGTYTSNVSTYLQDQ#AAKDFVSWL 63 |
Canis lupus familiaris | Query 40 PLEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 || | ||+||||||||||||||||||||||#|||||||||||||||+|||||||||||||| Sbjct 40 PLNDLDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNKNNIAKRHDEFERHA 99 Query 48 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 86 +| +||++|||||| | ||+ +# |++|+ ||+ + |+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQ#AAKEFIAWLVKGRGRRD 131 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 82 +||+ |+|+ + + ||+ # +||+ ||+ || Sbjct 144 RRHADGSFSDEMNTVLDTL#ATRDFINWLLQTK 175 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 85 |+ || ||| | +|+ +# ++|+ ||++ + | Sbjct 1 HADGTLTSDISSFLEKQ#ATKEFIAWLVSGRGRR 33 |
Sus scrofa | Query 40 PLEDPDQINEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 ||+||||+ |||||||||||||||||||||#|||||||||||||||+|||||||||||||| Sbjct 40 PLDDPDQMTEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNKNNIAKRHDEFERHA 99 Query 51 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 82 +||+ |+|+ + + ||+ # +||+ ||++|| Sbjct 144 RRHADGSFSDEMNTVLDNL#ATRDFINWLLHTK 175 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 56 GTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 85 ||+||| | || +# |++|| || | | | Sbjct 3 GTYTSDVSSYLQDQ#AAKEFVSWL-KTGRGR 31 |
Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 |||||||+|||||||+|#||||||||||+|||+ | || Sbjct 1 HSQGTFTNDYSKYLDTR#RAQDFVQWLMSTKRS-GGITXXXXXXXXHA 46 Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWL 78 |+ ||+||| | || +# |+ || || Sbjct 45 HADGTYTSDVSSYLQDQ#AAKKFVTWL 70 |
swine, intestines, Peptide Partial, 56 aa | Query 53 HSQGTFTSDYSKYLDSR#RAQDFVQWLM 79 || |||||+ |+ || #| | +| |+ Sbjct 30 HSDGTFTSELSRLRDSA#RLQRLLQGLV 56 |
swine, small intestine, Peptide Partial, 36 aa | Query 59 TSDYSKYLDSR#RAQDFVQWLMNTKRNRNN 87 |||| +| #| |||| ||+ | +++ Sbjct 1 ISDYSIAMDKI#RQQDFVNWLLAQKGKKSD 29 |
[Site 3] YLDSRRAQDF74-VQWLMNTKRN
Phe74 Val
iTraq-117 Signal 6465.1 () for NTKRN
P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
---|---|---|---|---|---|---|---|---|---|
Tyr65 | Leu66 | Asp67 | Ser68 | Arg69 | Arg70 | Ala71 | Gln72 | Asp73 | Phe74 |
P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
Val75 | Gln76 | Trp77 | Leu78 | Met79 | Asn80 | Thr81 | Lys82 | Arg83 | Asn84 |
Sequence conservation (by blast) Sequence conservation (by blast)
Reference peptide (cleaved bond±30 residues) |
---|
DQINEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFT |
Summary
# | organism | max score | hits | top seq |
---|---|---|---|---|
1 | N/A | 79.00 | 44 | 0810207A glucagon 37 |
2 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 63.20 | 1 | glucagon G-33 |
3 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 60.10 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
4 | Contains: Glucagon; Glucagon-like peptide | 59.30 | 3 | GLUC_AMICA Glucagon precursor |
5 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 59.30 | 1 | glucagon II |
6 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 58.90 | 1 | glucagon |
7 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 57.00 | 1 | glucagon G-29 |
8 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.20 | 1 | GLUC_LAMFL Glucagon gi |
9 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 55.80 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gi |
10 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 52.40 | 1 | glucagon |
11 | Xenopus laevis | 46.60 | 3 | proglucagon II |
12 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 45.40 | 1 | GLUC1_PETMA Glucagon-1 precursor |
13 | Hoplobatrachus rugulosus | 45.10 | 1 | AF324209_1 proglucagon |
14 | Homo sapiens | 44.70 | 6 | vasoactive intestinal peptide isoform 1 prepropro |
15 | Canis familiaris | 44.70 | 3 | PREDICTED: similar to Vasoactive intestinal pepti |
16 | Gallus gallus | 44.30 | 3 | glucagon isoform 1 |
17 | Meleagris gallopavo | 44.30 | 2 | preproglucagon B |
18 | Bos taurus | 44.30 | 1 | vasoactive intestinal peptide |
19 | Rattus norvegicus | 43.50 | 1 | gastric inhibitory polypeptide |
20 | Mus musculus | 41.60 | 6 | vasoactive intestinal polypeptide |
21 | Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | 41.60 | 1 | VIP_MOUSE VIP peptides precursor |
22 | Rattus norvegicus | 41.20 | 4 | PREDICTED: similar to VIP peptides precursor |
23 | Xenopus tropicalis | 41.20 | 1 | glucagon |
24 | Oncorhynchus tshawytscha | 40.80 | 1 | S78474_1 proglucagon |
25 | Arvicanthis ansorgei | 40.80 | 1 | vasoactive intestinal polypeptide |
26 | Mus musculus | 40.40 | 2 | Gastric inhibitory polypeptide |
27 | Heloderma suspectum | 39.70 | 2 | proglucagon |
28 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 39.70 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
29 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 39.70 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
30 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 39.70 | 1 | glucagon-like peptide, GLP |
31 | Bos taurus | 39.30 | 2 | PREDICTED: similar to Gastric inhibitory polypept |
32 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 39.30 | 2 | GLUC_CARAU Glucagon precursor |
33 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 38.90 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
34 | Tetraodon nigroviridis | 38.50 | 3 | unnamed protein product |
35 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 38.50 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
36 | Heloderma horridum | 38.10 | 1 | EXE3_HELHO Exendin-3 precursor gi |
37 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 37.00 | 1 | GLUC2_PETMA Glucagon-2 precursor |
38 | synthetic construct | 35.40 | 1 | Homo sapiens glucagon |
39 | Heloderma suspectum, venom, Peptide, 39 aa | 35.00 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30- |
40 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 35.00 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
41 | Danio rerio | 35.00 | 1 | glucagon polyprotein |
42 | Contains: Glucagon-1; Glucagon-like peptide 1-1 | 34.70 | 1 | GLUC1_ONCKI Glucagon-1 precursor |
43 | Canis lupus familiaris | 34.30 | 1 | glucagon |
44 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 33.90 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
45 | Sus scrofa | 33.90 | 1 | glucagon |
46 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 33.50 | 1 | GLUC_LEPSP Glucagon precursor |
47 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 33.10 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gi |
48 | Gallus gallus | 33.10 | 1 | growth hormone-releasing hormone/pituitary adenyl |
49 | Ambloplites rupestris | 33.10 | 1 | proglucagon |
50 | swine, intestines, Peptide Partial, 56 aa | 30.80 | 1 | secretin precursor, N-prosecretin, secretin-(-9 t |
51 | swine, small intestine, Peptide Partial, 36 aa | 30.00 | 1 | diazepam-binding inhibitor (32-86), DBI(32-86)=an |
Top-ranked sequences
organism | matching |
---|---|
N/A | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIA 89 ||||||||||||||||||||||#||||||||||+|||| Sbjct 1 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNKNNIA 37 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN 84 ||+||||||||||+|+|||+||#|||||+|||| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDF#VQWLMSTKRN 32 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 81 |||||||||||||||+||||||#+||||+| Sbjct 1 HSQGTFTSDYSKYLDNRRAQDF#IQWLMST 29 |
Contains: Glucagon; Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 81 |||||||+|||||+|+||||||#|||||+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDF#VQWLMST 29 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN 84 ||+|||++||||||++||||||#|||| |+||| Sbjct 1 HSEGTFSNDYSKYLETRRAQDF#VQWLKNSKRN 32 |
Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 81 |||||||+|||||+|+||||||#|||||+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDF#VQWLMST 29 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 81 ||+||||||||||+|+|||+||#|||||+| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDF#VQWLMST 29 |
Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 81 ||||+|||||||||||++|+||#| ||||| Sbjct 1 HSQGSFTSDYSKYLDSKQAKDF#VIWLMNT 29 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN 84 ||+|||++||||||+ |+||||#|+|||| ||+ Sbjct 1 HSEGTFSNDYSKYLEDRKAQDF#VRWLMNNKRS 32 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 81 ||+|||||||||||++++|+||#|+|||| Sbjct 1 HSEGTFTSDYSKYLENKQAKDF#VRWLMNA 29 |
Xenopus laevis | Query 45 DQINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 +|+ | ||||||||||||||||||||||||#|||||||||+ +++|+ ++||||||||| Sbjct 45 EQLKEVKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRS-GGLSRRNADYERHAEGTFT 103 Query 49 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 | +||++||+|+| ++||+ + + |#++||+ | + + |||||||| Sbjct 138 EIERHAEGTYTNDVTEYLEEKATKAF#IEWLIKGK-------PKKIRYSRHAEGTFT 186 Query 52 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRH 92 ||++||||+| + ||+ + |++|#| ||+| + | ++ + | Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEF#VGWLINGRPKRKDLLEEH 219 |
Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||||+|||||||||||++++|+||#|+|||| || + + + |||+|||| Sbjct 41 KRHSEGTFTSDYSKYLENKQAKDF#VRWLMNAKRGGSELQR------RHADGTFT 88 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIA---KRHDEFERHAE 100 +||+ ||||+| + |||++ |+||#| || + ++| + + | +|||| Sbjct 80 RRHADGTFTNDMTSYLDAKAARDF#VSWLARSDKSRRDGGDHLAENSEDKRHAE 132 |
Hoplobatrachus rugulosus | Query 45 DQINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 | || ||||||||||||||||||||||||#||||||+||+ |+||+ +||||||||+| Sbjct 45 DHHNEVKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNSKRS-GGISKRNVQFERHAEGTYT 103 Query 52 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFE-RHAEGTFT 104 ||++|||||| + ||+ + |++|#| ||+ + || +| + |||+|+|| Sbjct 134 RHAEGTFTSDMTSYLEEKAAKEF#VDWLIKGRPKRNFPDISAEEMDRRHADGSFT 187 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 +||++||+|+| +++|+ + |++|#+ ||+ | + ++ |||||||| Sbjct 95 ERHAEGTYTNDVTQFLEEKAAKEF#IDWLIKGKPKKQRLS-------RHAEGTFT 141 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 81 |+||+ |+||||++| || + ||+|#+ |++|| Sbjct 178 DRRHADGSFTSDFNKALDIKAAQEF#LDWIINT 209 |
Homo sapiens | Query 47 INEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ++ + ||+ | ||||+|| | |+ +#++ || || +||++ +||++ || Sbjct 75 VSRNARHADGVFTSDFSKLLGQLSAKKY#LESLMG-KRVSSNISEDPVPVKRHSDAVFT 131 |
Canis familiaris | Query 47 INEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ++ + ||+ | ||||+|+ | |+ +#++ |+ || |||++ +||++ || Sbjct 75 VSRNARHADGVFTSDFSRLLGQLSAKKY#LESLIG-KRVGNNISEDQGPIKRHSDAVFT 131 |
Gallus gallus | Query 46 QINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN------------------RNN 87 |+|| ||||||||||||||||||||||||#|||||+|||| | Sbjct 48 QLNEVKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMSTKRNGQQGQEDKENDKFPDQLSSNA 107 Query 88 IAKRHDEFERHAEGTFT 104 |+||| |||||||||+| Sbjct 108 ISKRHSEFERHAEGTYT 124 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFE---RHAEGTFT 104 +| +||++||+||| + ||+ + |++|#+ ||+| + |+ | | |||+|||| Sbjct 113 SEFERHAEGTYTSDITSYLEGQAAKEF#IAWLVNGRGRRDFPEKALMAEEMGRRHADGTFT 172 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNI 88 +||+ |||||| +| || |++|#++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEF#LKWLINTKVTQRDL 201 |
Meleagris gallopavo | Query 46 QINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN------------------RNN 87 |+|| ||||||||||||||||||||||||#|||||+|||| | Sbjct 48 QLNEVKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMSTKRNGQQGQEDKENDEFPDQLSSNA 107 Query 88 IAKRHDEFERHAEGTFT 104 |+||| |||||||||+| Sbjct 108 ISKRHSEFERHAEGTYT 124 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFE---RHAEGTFT 104 +| +||++||+||| + ||+ + |++|#+ ||+| + |+ | | |||+|||| Sbjct 113 SEFERHAEGTYTSDITSYLEGQAAKEF#IAWLVNGRGRRDFPEKALMAEEMGRRHADGTFT 172 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNI 88 +||+ |||||| +| || |++|#++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEF#LKWLINTKVTQRDL 201 |
Bos taurus | Query 47 INEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ++ + ||+ | ||||||+ | |+ +#++ |+ || |+|++ +||++ || Sbjct 75 VSRNVRHADGVFTSDYSRLLGQLSAKKY#LESLIG-KRVSNSISEDQGPIKRHSDAVFT 131 |
Rattus norvegicus | Query 52 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNN 87 |+++||| |||| +| | |||#| ||+ | +|+ Sbjct 43 RYAEGTFISDYSIAMDKIRQQDF#VNWLLAQKGKKND 78 |
Mus musculus | Query 47 INEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ++ + ||+ | ||||||+ | |+ +#++ |+ || ++|++ +||++ || Sbjct 76 VSRNARHADGVFTSDYSRLLGQISAKKY#LESLIG-KRISSSISEDPVPIKRHSDAVFT 132 |
Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | Query 47 INEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ++ + ||+ | ||||||+ | |+ +#++ |+ || ++|++ +||++ || Sbjct 75 VSRNARHADGVFTSDYSRLLGQISAKKY#LESLIG-KRISSSISEDPVPIKRHSDAVFT 131 |
Rattus norvegicus | Query 47 INEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ++ + ||+ | ||||||+ | |+ +#++ |+ || ++|++ +||++ || Sbjct 75 VSRNARHADGVFTSDYSRLLGQISAKKY#LESLIG-KRISSSISEDPVPVKRHSDAVFT 131 |
Xenopus tropicalis | Query 46 QINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 |+ | ||||||||||||||||||||||||#+||||||||+ +++|+ ++||||||||| Sbjct 46 QLKEVKRHSQGTFTSDYSKYLDSRRAQDF#IQWLMNTKRS-GGLSRRNADYERHAEGTFT 103 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 +||++|||||| +++|| + |++|#+ ||+| ++ |++|+ + |||||||+| Sbjct 95 ERHAEGTFTSDVTQHLDEKAAKEF#IDWLINGGPSKEIISRRNADVERHAEGTYT 148 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 +||++||+|+| ++||+ + |++|#++||+| | + + |||||||| Sbjct 140 ERHAEGTYTNDVTEYLEEKAAKEF#IEWLINGK-------PKKIRYSRHAEGTFT 186 Query 52 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFE---RHAEGTFT 104 ||++||||+| + ||+ + |++|#| ||+ | + | ++ | | |||+|+|| Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEF#VGWLIK-GRPKRNFSEAHSVEEMDRRHADGSFT 233 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 82 |+||+ |+||+| +| || ||+|#+ |++||+ Sbjct 224 DRRHADGSFTNDINKVLDIIAAQEF#LDWVINTQ 256 |
Oncorhynchus tshawytscha | Query 54 SQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 | |||++||||| + | ||||#||||||+||+ +|||+||+| Sbjct 2 SXGTFSNDYSKYQEERMAQDF#VQWLMNSKRS-------GAPSKRHADGTYT 45 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 85 |||+ ||+||| | || + |+||#| || + + | Sbjct 37 KRHADGTYTSDVSTYLQDQAAKDF#VSWLKSGRARR 71 |
Arvicanthis ansorgei | Query 47 INEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ++ + ||+ | ||||||+ | |+ +#++ |+ || ++| + +||++ || Sbjct 58 VSRNARHADGVFTSDYSRLLGQISAKKY#LESLIG-KRISSSILEDPVPIKRHSDAVFT 114 |
Mus musculus | Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN----NIAKRH 92 |+++||| |||| +| | |||#| ||+ + ++ || +| Sbjct 42 PRYAEGTFISDYSIAMDKIRQQDF#VNWLLAQRGKKSDWKHNITQRE 87 |
Heloderma suspectum | Query 46 QINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKR------------------NRNN 87 |+|| |||||||||||||||||+||||||#||||||||| + | Sbjct 46 QLNEVKRHSQGTFTSDYSKYLDTRRAQDF#VQWLMNTKRSGQQGVEEREKENLLDQLSSNG 105 Query 88 IAKRHDEFERHAEGTFT 104 +|+ | |+||||+| +| Sbjct 106 LARHHAEYERHADGRYT 122 Query 49 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 85 | +||+ | +||| | ||+ + |++|#+ ||+| + | Sbjct 112 EYERHADGRYTSDISSYLEGQAAKEF#IAWLVNGRGRR 148 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||||+|||++||||||++||||||#|||| |+||| | |||+||+| Sbjct 50 KRHSEGTFSNDYSKYLETRRAQDF#VQWLKNSKRN--------GLFRRHADGTYT 95 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWL 78 +||+ ||+||| | || + |+||#| || Sbjct 87 RRHADGTYTSDVSSYLQDQAAKDF#VSWL 114 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 82 |+ |+|||| +| ||+ |++|#+ ||++|| Sbjct 1 HADGSFTSDINKVLDTIAAKEF#LNWLISTK 30 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN 84 |+ ||||+| + |||++ |+||#| || + ++ Sbjct 1 HADGTFTNDMTSYLDAKAARDF#VSWLARSDKS 32 |
Bos taurus | Query 52 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNN 87 |+++||| |||| +| | |||#| ||+ | +++ Sbjct 81 RYAEGTFISDYSIAMDKIRQQDF#VNWLLAQKGKKSD 116 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||||+|||++||||||++||||||#|+||||+| | + +||||||+| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDF#VEWLMNSKSNGGSA-------KRHAEGTYT 94 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWL 78 |||++||+||| | +| + ||+|#| || Sbjct 86 KRHAEGTYTSDISSFLRDQAAQNF#VAWL 113 |
Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 47 INEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ++ ||||+|||++||||| + | ||||#||||||+||+ +|||+||+| Sbjct 46 VSNVKRHSEGTFSNDYSKYQEERMAQDF#VQWLMNSKRS-------GAPSKRHADGTYT 96 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNI--AKRHDEFERHAEGTFT 104 |||+ ||+||| | || + |+||#| || + + | + ++ || +|+|| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDF#VSWLKSGRARRESAEESRNGPMSRRHVDGSFT 143 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 82 +|| |+|||| +| ||| |+++#+ |+| +| Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEY#LLWVMTSK 166 |
Tetraodon nigroviridis | Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||||+|||++||||||++||||||#|||| |+||| + | |||+||+| Sbjct 787 KRHSEGTFSNDYSKYLETRRAQDF#VQWLKNSKRNGS-------LFRRHADGTYT 833 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 85 +||+ ||+||| | || + |++|#| || | | | Sbjct 825 RRHADGTYTSDVSAYLQDQAAKEF#VSWL-KTGRGR 858 |
Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 || |+|||++ |||| + | |+||#+ ||||+||+ +|||+||+| Sbjct 50 KRQSEGTFSNYYSKYQEERMARDF#LHWLMNSKRSGA-------PSKRHADGTYT 96 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEF--ERHAEGTFT 104 |||+ ||+||| | || + |+||#| || + | + + + || +|+|| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDF#VSWLKSGPARRESAEESMNGPMSRRHVDGSFT 143 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 82 +|| |+|||| +| ||| |+++#+ |+| +| Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEY#LLWVMTSK 166 |
Heloderma horridum | Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMN 80 |||| |||||| || ++ + |#++|| | Sbjct 46 KRHSDGTFTSDLSKQMEEEAVRLF#IEWLKN 75 |
Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 46 QINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 +|+ |||||+|||||||+|| ++|+||#| ||+|||| + + +||++|+|| Sbjct 37 EISLANRHSQGSFTSDYSKHLDVKQAKDF#VTWLLNTKRRGVDAQAGANLEKRHSDGSFT 95 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWL 78 | +|||| |+||+| + || |++|#++|| Sbjct 84 NLEKRHSDGSFTNDMNVMLDRMSAKNF#LEWL 114 |
synthetic construct | Query 45 DQINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+|||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 45 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN---NIAKRHDEFERHAEGTFT 104 +| +||++|||||| | ||+ + |++|#+ ||+ + |+ +| + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEF#IAWLVKGRGRRDFPEEVAIVEELGRRHADGSFS 152 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 82 +||+ |+|+ + + ||+ |+||#+ ||+ || Sbjct 144 RRHADGSFSDEMNTILDNLAARDF#INWLIQTK 175 |
Heloderma suspectum, venom, Peptide, 39 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMN 80 | +|||||| || ++ + |#++|| | Sbjct 1 HGEGTFTSDLSKQMEEEAVRLF#IEWLKN 28 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 46 QINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 +++ ||||+|||++||||||+ |+||+|#|+|||| | |+ +|++ |||+|||| Sbjct 46 ELSNMKRHSEGTFSNDYSKYLEDRKAQEF#VRWLMNNK--RSGVAEK-----RHADGTFT 97 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWL 78 +|||+ |||||| | || + +||#| | Sbjct 88 EKRHADGTFTSDVSSYLKDQAIKDF#VDRL 116 |
Danio rerio | Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||||+|||++||||||++||||||#|||||| ||| ++ +||||||+| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDF#VQWLMNAKRNGGSV-------KRHAEGTYT 94 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWL 78 |||++||+||| | || + || |#| | Sbjct 86 KRHAEGTYTSDVSSYLQDQAAQRF#VARL 113 |
Contains: Glucagon-1; Glucagon-like peptide 1-1 | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+|||++||||| + | ||||#||||||+ ||+||+| Sbjct 1 HSEGTFSNDYSKYQEERMAQDF#VQWLMNSXXXXXX--------XXHADGTYT 44 Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWL 78 |+ ||+||+ | || + |+||#| || Sbjct 38 HADGTYTSNVSTYLQDQAAKDF#VSWL 63 |
Canis lupus familiaris | Query 45 DQINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+|||||||||||||||||||||||||||#||||||||||+||||||||||||||||||| Sbjct 45 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNKNNIAKRHDEFERHAEGTFT 104 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN---NIAKRHDEFERHAEGTFT 104 +| +||++|||||| | ||+ + |++|#+ ||+ + |+ +| + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEF#IAWLVKGRGRRDFPEEVAIVEEFRRRHADGSFS 152 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 82 +||+ |+|+ + + ||+ +||#+ ||+ || Sbjct 144 RRHADGSFSDEMNTVLDTLATRDF#INWLLQTK 175 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 85 |+ || ||| | +|+ + ++|#+ ||++ + | Sbjct 1 HADGTLTSDISSFLEKQATKEF#IAWLVSGRGRR 33 |
Sus scrofa | Query 45 DQINEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ ||||||||||||||||||||||||||#||||||||||+||||||||||||||||||| Sbjct 45 DQMTEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNKNNIAKRHDEFERHAEGTFT 104 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN---NIAKRHDEFERHAEGTFT 104 +| +||++|||||| | ||+ + |++|#+ ||+ + |+ + + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEF#IAWLVKGRGRRDFPEEVTIVEELRRRHADGSFS 152 Query 51 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 82 +||+ |+|+ + + ||+ +||#+ ||++|| Sbjct 144 RRHADGSFSDEMNTVLDNLATRDF#INWLLHTK 175 |
Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 |||||||+|||||||+||||||#|||||+|||+ | ||+||+| Sbjct 1 HSQGTFTNDYSKYLDTRRAQDF#VQWLMSTKRS-GGITXXXXXXXXHADGTYT 51 Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWL 78 |+ ||+||| | || + |+ |#| || Sbjct 45 HADGTYTSDVSSYLQDQAAKKF#VTWL 70 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 56 GTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNN 87 ||+||| | || + |++|#| || | | | + Sbjct 3 GTYTSDVSSYLQDQAAKEF#VSWL-KTGRGRRD 33 |
Gallus gallus | Query 49 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEF-ERHAEGTFT 104 |||+ | |+ | | | |+++#+ || || + + + +|| +| || Sbjct 79 PGKRHADGIFSKAYRKLLGQLSARNY#LHSLM-AKRVGSGLGDEAEPLSKRHIDGIFT 134 |
Ambloplites rupestris | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 104 |||||||+||+ ||+ |+||||#++|||| | |+ |++ |||+|||| Sbjct 1 HSQGTFTNDYTNYLEDRQAQDF#IRWLMNNK--RSGAAEK-----RHADGTFT 45 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK-RNRNNIAKRHDEFE-RHAEGTFT 104 +|||+ |||| | | + +||#| | + + | +| + | || ||+|| Sbjct 36 EKRHADGTFTDDASSDFYDQAIKDF#VAKLKSGQDRREPETDRRREAFSRRHVEGSFT 92 |
swine, intestines, Peptide Partial, 56 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDF#VQWLM 79 || |||||+ |+ || | | #+| |+ Sbjct 30 HSDGTFTSELSRLRDSARLQRL#LQGLV 56 |
swine, small intestine, Peptide Partial, 36 aa | Query 59 TSDYSKYLDSRRAQDF#VQWLMNTKRNRNN 87 |||| +| | |||#| ||+ | +++ Sbjct 1 ISDYSIAMDKIRQQDF#VNWLLAQKGKKSD 29 |
[Site 4] SRRAQDFVQW77-LMNTKRNRNN
Trp77 Leu
P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
---|---|---|---|---|---|---|---|---|---|
Ser68 | Arg69 | Arg70 | Ala71 | Gln72 | Asp73 | Phe74 | Val75 | Gln76 | Trp77 |
P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
Leu78 | Met79 | Asn80 | Thr81 | Lys82 | Arg83 | Asn84 | Arg85 | Asn86 | Asn87 |
Sequence conservation (by blast) Sequence conservation (by blast)
Reference peptide (cleaved bond±30 residues) |
---|
NEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDV |
Summary
# | organism | max score | hits | top seq |
---|---|---|---|---|
1 | N/A | 79.00 | 45 | 0810207A glucagon 37 |
2 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 62.80 | 1 | glucagon G-33 |
3 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 60.50 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
4 | Contains: Glucagon; Glucagon-like peptide | 60.10 | 3 | GLUC_AMICA Glucagon precursor |
5 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 59.30 | 1 | glucagon II |
6 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 58.90 | 1 | glucagon |
7 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 57.00 | 1 | glucagon G-29 |
8 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.20 | 1 | GLUC_LAMFL Glucagon gi |
9 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 55.80 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gi |
10 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 52.40 | 1 | glucagon |
11 | Xenopus laevis | 46.60 | 3 | proglucagon II |
12 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 45.40 | 1 | GLUC1_PETMA Glucagon-1 precursor |
13 | Hoplobatrachus rugulosus | 45.10 | 1 | AF324209_1 proglucagon |
14 | Gallus gallus | 44.70 | 3 | glucagon isoform 1 |
15 | Meleagris gallopavo | 44.30 | 2 | preproglucagon B |
16 | Canis familiaris | 43.90 | 3 | PREDICTED: similar to Vasoactive intestinal pepti |
17 | Rattus norvegicus | 43.50 | 1 | gastric inhibitory polypeptide |
18 | Bos taurus | 43.50 | 1 | vasoactive intestinal peptide |
19 | Homo sapiens | 43.10 | 6 | vasoactive intestinal peptide isoform 1 prepropro |
20 | Xenopus tropicalis | 41.20 | 1 | glucagon |
21 | Mus musculus | 40.80 | 6 | unnamed protein product |
22 | Mus musculus | 40.80 | 2 | Gastric inhibitory polypeptide |
23 | Oncorhynchus tshawytscha | 40.40 | 1 | S78474_1 proglucagon |
24 | Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | 40.40 | 1 | VIP_MOUSE VIP peptides precursor |
25 | Rattus norvegicus | 40.00 | 4 | PREDICTED: similar to VIP peptides precursor |
26 | Bos taurus | 39.70 | 2 | PREDICTED: similar to Gastric inhibitory polypept |
27 | Heloderma suspectum | 39.70 | 2 | proglucagon |
28 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 39.70 | 2 | GLUC_CARAU Glucagon precursor |
29 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 39.70 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
30 | Arvicanthis ansorgei | 39.70 | 1 | vasoactive intestinal polypeptide |
31 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 39.70 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
32 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 39.70 | 1 | glucagon-like peptide, GLP |
33 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 38.50 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
34 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 38.50 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
35 | Tetraodon nigroviridis | 38.10 | 3 | unnamed protein product |
36 | Heloderma horridum | 38.10 | 1 | EXE3_HELHO Exendin-3 precursor gi |
37 | Ambloplites rupestris | 37.70 | 1 | proglucagon |
38 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 37.00 | 1 | GLUC2_PETMA Glucagon-2 precursor |
39 | synthetic construct | 35.40 | 1 | Homo sapiens glucagon |
40 | Heloderma suspectum, venom, Peptide, 39 aa | 35.00 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30- |
41 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 35.00 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
42 | Danio rerio | 35.00 | 1 | glucagon polyprotein |
43 | Canis lupus familiaris | 34.30 | 1 | glucagon |
44 | Contains: Glucagon-1; Glucagon-like peptide 1-1 | 34.30 | 1 | GLUC1_ONCKI Glucagon-1 precursor |
45 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 33.90 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
46 | Sus scrofa | 33.90 | 1 | glucagon |
47 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 33.10 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gi |
48 | Gallus gallus | 33.10 | 1 | growth hormone-releasing hormone/pituitary adenyl |
49 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 33.10 | 1 | GLUC_LEPSP Glucagon precursor |
50 | swine, intestines, Peptide Partial, 56 aa | 30.80 | 1 | secretin precursor, N-prosecretin, secretin-(-9 t |
51 | swine, small intestine, Peptide Partial, 36 aa | 30.00 | 1 | diazepam-binding inhibitor (32-86), DBI(32-86)=an |
Top-ranked sequences
organism | matching |
---|---|
N/A | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIA 89 |||||||||||||||||||||||||#|||||||+|||| Sbjct 1 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNKNNIA 37 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN 84 ||+||||||||||+|+|||+|||||#||+|||| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDFVQW#LMSTKRN 32 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 81 |||||||||||||||+||||||+||#||+| Sbjct 1 HSQGTFTSDYSKYLDNRRAQDFIQW#LMST 29 |
Contains: Glucagon; Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 |||||||+|||||+|+|||||||||#||+| +|+ + ||| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDFVQW#LMSTXXXXXXXXXXXXX-XXYADAPYISDV 54 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN 84 ||+|||++||||||++|||||||||#| |+||| Sbjct 1 HSEGTFSNDYSKYLETRRAQDFVQW#LKNSKRN 32 |
Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 81 |||||||+|||||+|+|||||||||#||+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDFVQW#LMST 29 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 81 ||+||||||||||+|+|||+|||||#||+| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDFVQW#LMST 29 |
Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 81 ||||+|||||||||||++|+||| |#|||| Sbjct 1 HSQGSFTSDYSKYLDSKQAKDFVIW#LMNT 29 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN 84 ||+|||++||||||+ |+|||||+|#||| ||+ Sbjct 1 HSEGTFSNDYSKYLEDRKAQDFVRW#LMNNKRS 32 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 81 ||+|||||||||||++++|+|||+|#||| Sbjct 1 HSEGTFTSDYSKYLENKQAKDFVRW#LMNA 29 |
Xenopus laevis | Query 49 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 | |||||||||||||||||||||||||||#||||||+ +++|+ ++|||||||||||| Sbjct 49 EVKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRS-GGLSRRNADYERHAEGTFTSDV 106 Query 49 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 | +||++||+|+| ++||+ + + |++|#|+ | + + ||||||||+|+ Sbjct 138 EIERHAEGTYTNDVTEYLEEKATKAFIEW#LIKGK-------PKKIRYSRHAEGTFTNDM 189 Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRH 92 ||++||||+| + ||+ + |++|| |#|+| + | ++ + | Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEFVGW#LINGRPKRKDLLEEH 219 |
Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||||+|||||||||||++++|+|||+|#||| || + + + |||+||||+|+ Sbjct 41 KRHSEGTFTSDYSKYLENKQAKDFVRW#LMNAKRGGSELQR------RHADGTFTNDM 91 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIA---KRHDEFERHAE 100 +||+ ||||+| + |||++ |+||| |#| + ++| + + | +|||| Sbjct 80 RRHADGTFTNDMTSYLDAKAARDFVSW#LARSDKSRRDGGDHLAENSEDKRHAE 132 |
Hoplobatrachus rugulosus | Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 || |||||||||||||||||||||||||||#|||+||+ |+||+ +||||||||+|+|| Sbjct 48 NEVKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNSKRS-GGISKRNVQFERHAEGTYTNDV 106 Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFE-RHAEGTFTSD 106 ||++|||||| + ||+ + |++|| |#|+ + || +| + |||+|+|||| Sbjct 134 RHAEGTFTSDMTSYLEEKAAKEFVDW#LIKGRPKRNFPDISAEEMDRRHADGSFTSD 189 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 +||++||+|+| +++|+ + |++|+ |#|+ | + ++ ||||||||||+ Sbjct 95 ERHAEGTYTNDVTQFLEEKAAKEFIDW#LIKGKPKKQRLS-------RHAEGTFTSDM 144 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 81 |+||+ |+||||++| || + ||+|+ |#++|| Sbjct 178 DRRHADGSFTSDFNKALDIKAAQEFLDW#IINT 209 |
Gallus gallus | Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN------------------RNNIA 89 || |||||||||||||||||||||||||||#||+|||| | |+ Sbjct 50 NEVKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMSTKRNGQQGQEDKENDKFPDQLSSNAIS 109 Query 90 KRHDEFERHAEGTFTSDV 107 ||| |||||||||+|||+ Sbjct 110 KRHSEFERHAEGTYTSDI 127 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFE---RHAEGTFT 104 +| +||++||+||| + ||+ + |++|+ |#|+| + |+ | | |||+|||| Sbjct 113 SEFERHAEGTYTSDITSYLEGQAAKEFIAW#LVNGRGRRDFPEKALMAEEMGRRHADGTFT 172 Query 105 SDV 107 ||+ Sbjct 173 SDI 175 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNI 88 +||+ |||||| +| || |++|++|#|+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEFLKW#LINTKVTQRDL 201 |
Meleagris gallopavo | Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN------------------RNNIA 89 || |||||||||||||||||||||||||||#||+|||| | |+ Sbjct 50 NEVKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMSTKRNGQQGQEDKENDEFPDQLSSNAIS 109 Query 90 KRHDEFERHAEGTFTSDV 107 ||| |||||||||+|||+ Sbjct 110 KRHSEFERHAEGTYTSDI 127 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFE---RHAEGTFT 104 +| +||++||+||| + ||+ + |++|+ |#|+| + |+ | | |||+|||| Sbjct 113 SEFERHAEGTYTSDITSYLEGQAAKEFIAW#LVNGRGRRDFPEKALMAEEMGRRHADGTFT 172 Query 105 SDV 107 ||+ Sbjct 173 SDI 175 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNI 88 +||+ |||||| +| || |++|++|#|+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEFLKW#LINTKVTQRDL 201 |
Canis familiaris | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||+|+ | |+ +++ #|+ || |||++ +||++ || Sbjct 80 RHADGVFTSDFSRLLGQLSAKKYLES#LIG-KRVGNNISEDQGPIKRHSDAVFT 131 |
Rattus norvegicus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNN 87 |+++||| |||| +| | |||| |#|+ | +|+ Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNW#LLAQKGKKND 78 |
Bos taurus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||||+ | |+ +++ #|+ || |+|++ +||++ || Sbjct 80 RHADGVFTSDYSRLLGQLSAKKYLES#LIG-KRVSNSISEDQGPIKRHSDAVFT 131 |
Homo sapiens | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||+|| | |+ +++ #|| || +||++ +||++ || Sbjct 80 RHADGVFTSDFSKLLGQLSAKKYLES#LMG-KRVSSNISEDPVPVKRHSDAVFT 131 |
Xenopus tropicalis | Query 49 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 | ||||||||||||||||||||||||+||#||||||+ +++|+ ++|||||||||||| Sbjct 49 EVKRHSQGTFTSDYSKYLDSRRAQDFIQW#LMNTKRS-GGLSRRNADYERHAEGTFTSDV 106 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 +||++||+|+| ++||+ + |++|++|#|+| | + + ||||||||+|+ Sbjct 140 ERHAEGTYTNDVTEYLEEKAAKEFIEW#LINGK-------PKKIRYSRHAEGTFTNDM 189 Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFE---RHAEGTFTSDV 107 ||++||||+| + ||+ + |++|| |#|+ | + | ++ | | |||+|+||+|+ Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEFVGW#LIK-GRPKRNFSEAHSVEEMDRRHADGSFTNDI 236 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 82 |+||+ |+||+| +| || ||+|+ |#++||+ Sbjct 224 DRRHADGSFTNDINKVLDIIAAQEFLDW#VINTQ 256 |
Mus musculus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN----NIAKRH 92 |+++||| |||| +| | |||| |#|+ + ++ || +| Sbjct 29 RYAEGTFISDYSIAMDKIRQQDFVNW#LLAQRGKKSDWKHNITQRE 73 |
Mus musculus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN----NIAKRH 92 |+++||| |||| +| | |||| |#|+ + ++ || +| Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNW#LLAQRGKKSDWKHNITQRE 87 |
Oncorhynchus tshawytscha | Query 54 SQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 | |||++||||| + | |||||||#|||+||+ +|||+||+|||| Sbjct 2 SXGTFSNDYSKYQEERMAQDFVQW#LMNSKRS-------GAPSKRHADGTYTSDV 48 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 85 |||+ ||+||| | || + |+||| |#| + + | Sbjct 37 KRHADGTYTSDVSTYLQDQAAKDFVSW#LKSGRARR 71 |
Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||||+ | |+ +++ #|+ || ++|++ +||++ || Sbjct 80 RHADGVFTSDYSRLLGQISAKKYLES#LIG-KRISSSISEDPVPIKRHSDAVFT 131 |
Rattus norvegicus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||||+ | |+ +++ #|+ || ++|++ +||++ || Sbjct 80 RHADGVFTSDYSRLLGQISAKKYLES#LIG-KRISSSISEDPVPVKRHSDAVFT 131 |
Bos taurus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNN 87 |+++||| |||| +| | |||| |#|+ | +++ Sbjct 81 RYAEGTFISDYSIAMDKIRQQDFVNW#LLAQKGKKSD 116 |
Heloderma suspectum | Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKR------------------NRNNIA 89 || |||||||||||||||||+|||||||||#|||||| + | +| Sbjct 48 NEVKRHSQGTFTSDYSKYLDTRRAQDFVQW#LMNTKRSGQQGVEEREKENLLDQLSSNGLA 107 Query 90 KRHDEFERHAEGTFTSDV 107 + | |+||||+| +|||+ Sbjct 108 RHHAEYERHADGRYTSDI 125 Query 49 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 85 | +||+ | +||| | ||+ + |++|+ |#|+| + | Sbjct 112 EYERHADGRYTSDISSYLEGQAAKEFIAW#LVNGRGRR 148 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||||+|||++||||||++|||||||+|#|||+| | + +||||||+|||+ Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDFVEW#LMNSKSNGGSA-------KRHAEGTYTSDI 97 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#L 78 |||++||+||| | +| + ||+|| |#| Sbjct 86 KRHAEGTYTSDISSFLRDQAAQNFVAW#L 113 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 82 |+ |+|||| +| ||+ |++|+ |#|++|| Sbjct 1 HADGSFTSDINKVLDTIAAKEFLNW#LISTK 30 |
Arvicanthis ansorgei | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||||+ | |+ +++ #|+ || ++| + +||++ || Sbjct 63 RHADGVFTSDYSRLLGQISAKKYLES#LIG-KRISSSILEDPVPIKRHSDAVFT 114 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||||+|||++||||||++|||||||||#| |+||| | |||+||+|||| Sbjct 50 KRHSEGTFSNDYSKYLETRRAQDFVQW#LKNSKRN--------GLFRRHADGTYTSDV 98 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#L 78 +||+ ||+||| | || + |+||| |#| Sbjct 87 RRHADGTYTSDVSSYLQDQAAKDFVSW#L 114 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN 84 |+ ||||+| + |||++ |+||| |#| + ++ Sbjct 1 HADGTFTNDMTSYLDAKAARDFVSW#LARSDKS 32 |
Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 || |+|||++ |||| + | |+||+ |#|||+||+ +|||+||+|||| Sbjct 50 KRQSEGTFSNYYSKYQEERMARDFLHW#LMNSKRSGA-------PSKRHADGTYTSDV 99 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEF--ERHAEGTFTSDV 107 |||+ ||+||| | || + |+||| |#| + | + + + || +|+||||| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDFVSW#LKSGPARRESAEESMNGPMSRRHVDGSFTSDV 146 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 82 +|| |+|||| +| ||| |++++ |#+| +| Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEYLLW#VMTSK 166 |
Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||||+|||++||||| + | |||||||#|||+||+ +|||+||+|||| Sbjct 50 KRHSEGTFSNDYSKYQEERMAQDFVQW#LMNSKRS-------GAPSKRHADGTYTSDV 99 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNI--AKRHDEFERHAEGTFTSDV 107 |||+ ||+||| | || + |+||| |#| + + | + ++ || +|+||||| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDFVSW#LKSGRARRESAEESRNGPMSRRHVDGSFTSDV 146 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 82 +|| |+|||| +| ||| |++++ |#+| +| Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEYLLW#VMTSK 166 |
Tetraodon nigroviridis | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||||+|||++||||||++|||||||||#| |+||| + | |||+||+|||| Sbjct 787 KRHSEGTFSNDYSKYLETRRAQDFVQW#LKNSKRNGS-------LFRRHADGTYTSDV 836 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 85 +||+ ||+||| | || + |++|| |#| | | | Sbjct 825 RRHADGTYTSDVSAYLQDQAAKEFVSW#L-KTGRGR 858 |
Heloderma horridum | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMN 80 |||| |||||| || ++ + |++|#| | Sbjct 46 KRHSDGTFTSDLSKQMEEEAVRLFIEW#LKN 75 |
Ambloplites rupestris | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 |||||||+||+ ||+ |+||||++|#||| | |+ |++ |||+|||| | Sbjct 1 HSQGTFTNDYTNYLEDRQAQDFIRW#LMNNK--RSGAAEK-----RHADGTFTDDA 48 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK-RNRNNIAKRHDEFE-RHAEGTFTSDV 107 +|||+ |||| | | + +||| #| + + | +| + | || ||+||||+ Sbjct 36 EKRHADGTFTDDASSDFYDQAIKDFVAK#LKSGQDRREPETDRRREAFSRRHVEGSFTSDI 95 |
Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 |||||+|||||||+|| ++|+||| |#|+|||| + + +||++|+||+|+ Sbjct 43 RHSQGSFTSDYSKHLDVKQAKDFVTW#LLNTKRRGVDAQAGANLEKRHSDGSFTNDM 98 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#L 78 | +|||| |+||+| + || |++|++|#| Sbjct 84 NLEKRHSDGSFTNDMNVMLDRMSAKNFLEW#L 114 |
synthetic construct | Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN---NIAKRHDEFERHAEGTFT 104 +| +||++|||||| | ||+ + |++|+ |#|+ + |+ +| + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEFIAW#LVKGRGRRDFPEEVAIVEELGRRHADGSFS 152 Query 105 SDV 107 ++ Sbjct 153 DEM 155 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 82 +||+ |+|+ + + ||+ |+||+ |#|+ || Sbjct 144 RRHADGSFSDEMNTILDNLAARDFINW#LIQTK 175 |
Heloderma suspectum, venom, Peptide, 39 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMN 80 | +|||||| || ++ + |++|#| | Sbjct 1 HGEGTFTSDLSKQMEEEAVRLFIEW#LKN 28 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||||+|||++||||||+ |+||+||+|#||| | |+ +|++ |||+||||||| Sbjct 51 KRHSEGTFSNDYSKYLEDRKAQEFVRW#LMNNK--RSGVAEK-----RHADGTFTSDV 100 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#L 78 +|||+ |||||| | || + +||| #| Sbjct 88 EKRHADGTFTSDVSSYLKDQAIKDFVDR#L 116 |
Danio rerio | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||||+|||++||||||++|||||||||#||| ||| ++ +||||||+|||| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDFVQW#LMNAKRNGGSV-------KRHAEGTYTSDV 97 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#L 78 |||++||+||| | || + || || #| Sbjct 86 KRHAEGTYTSDVSSYLQDQAAQRFVAR#L 113 |
Canis lupus familiaris | Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||||||||||||||||||||||||||||||#|||||||+|||||||||||||||||||||| Sbjct 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNKNNIAKRHDEFERHAEGTFTSDV 107 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN---NIAKRHDEFERHAEGTFT 104 +| +||++|||||| | ||+ + |++|+ |#|+ + |+ +| + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEFIAW#LVKGRGRRDFPEEVAIVEEFRRRHADGSFS 152 Query 105 SDV 107 ++ Sbjct 153 DEM 155 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 82 +||+ |+|+ + + ||+ +||+ |#|+ || Sbjct 144 RRHADGSFSDEMNTVLDTLATRDFINW#LLQTK 175 |
Contains: Glucagon-1; Glucagon-like peptide 1-1 | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 ||+|||++||||| + | |||||||#|||+ ||+||+||+| Sbjct 1 HSEGTFSNDYSKYQEERMAQDFVQW#LMNSXXXXXX--------XXHADGTYTSNV 47 Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#L 78 |+ ||+||+ | || + |+||| |#| Sbjct 38 HADGTYTSNVSTYLQDQAAKDFVSW#L 63 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN 86 |+ || ||| | +|+ + ++|+ |#|++ + | Sbjct 1 HADGTLTSDISSFLEKQATKEFIAW#LVSGRGRRQ 34 |
Sus scrofa | Query 49 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 |||||||||||||||||||||||||||||#|||||||+|||||||||||||||||||||| Sbjct 49 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNKNNIAKRHDEFERHAEGTFTSDV 107 Query 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN---NIAKRHDEFERHAEGTFT 104 +| +||++|||||| | ||+ + |++|+ |#|+ + |+ + + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEFIAW#LVKGRGRRDFPEEVTIVEELRRRHADGSFS 152 Query 105 SDV 107 ++ Sbjct 153 DEM 155 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 82 +||+ |+|+ + + ||+ +||+ |#|++|| Sbjct 144 RRHADGSFSDEMNTVLDNLATRDFINW#LLHTK 175 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 56 GTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNN 87 ||+||| | || + |++|| |#| | | | + Sbjct 3 GTYTSDVSSYLQDQAAKEFVSW#L-KTGRGRRD 33 |
Gallus gallus | Query 49 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEF-ERHAEGTFT 104 |||+ | |+ | | | |++++ #|| || + + + +|| +| || Sbjct 79 PGKRHADGIFSKAYRKLLGQLSARNYLHS#LM-AKRVGSGLGDEAEPLSKRHIDGIFT 134 |
Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 107 |||||||+|||||||+|||||||||#||+|||+ | ||+||+|||| Sbjct 1 HSQGTFTNDYSKYLDTRRAQDFVQW#LMSTKRS-GGITXXXXXXXXHADGTYTSDV 54 Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#L 78 |+ ||+||| | || + |+ || |#| Sbjct 45 HADGTYTSDVSSYLQDQAAKKFVTW#L 70 |
swine, intestines, Peptide Partial, 56 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQW#LM 79 || |||||+ |+ || | | +| #|+ Sbjct 30 HSDGTFTSELSRLRDSARLQRLLQG#LV 56 |
swine, small intestine, Peptide Partial, 36 aa | Query 59 TSDYSKYLDSRRAQDFVQW#LMNTKRNRNN 87 |||| +| | |||| |#|+ | +++ Sbjct 1 ISDYSIAMDKIRQQDFVNW#LLAQKGKKSD 29 |
[Site 5] RAQDFVQWLM79-NTKRNRNNIA
Met79 Asn
P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
---|---|---|---|---|---|---|---|---|---|
Arg70 | Ala71 | Gln72 | Asp73 | Phe74 | Val75 | Gln76 | Trp77 | Leu78 | Met79 |
P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
Asn80 | Thr81 | Lys82 | Arg83 | Asn84 | Arg85 | Asn86 | Asn87 | Ile88 | Ala89 |
Sequence conservation (by blast) Sequence conservation (by blast)
Reference peptide (cleaved bond±30 residues) |
---|
DKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSS |
Summary
# | organism | max score | hits | top seq |
---|---|---|---|---|
1 | N/A | 79.00 | 44 | 0810207A glucagon 37 |
2 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 63.20 | 1 | glucagon G-33 |
3 | Contains: Glucagon; Glucagon-like peptide | 60.80 | 3 | GLUC_AMICA Glucagon precursor |
4 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 60.10 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
5 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 59.30 | 1 | glucagon II |
6 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 58.90 | 1 | glucagon |
7 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 57.00 | 1 | glucagon G-29 |
8 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 56.20 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gi |
9 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.20 | 1 | GLUC_LAMFL Glucagon gi |
10 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 52.40 | 1 | glucagon |
11 | Xenopus laevis | 47.00 | 3 | proglucagon II |
12 | Hoplobatrachus rugulosus | 45.10 | 1 | AF324209_1 proglucagon |
13 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 45.10 | 1 | GLUC1_PETMA Glucagon-1 precursor |
14 | Gallus gallus | 44.70 | 3 | glucagon isoform 1 |
15 | Meleagris gallopavo | 44.70 | 2 | preproglucagon B |
16 | Canis familiaris | 43.90 | 3 | PREDICTED: similar to Gastric inhibitory polypept |
17 | Rattus norvegicus | 43.90 | 1 | gastric inhibitory polypeptide |
18 | Bos taurus | 43.10 | 1 | vasoactive intestinal peptide |
19 | Homo sapiens | 42.70 | 6 | vasoactive intestinal peptide isoform 1 prepropro |
20 | Xenopus tropicalis | 41.60 | 1 | glucagon |
21 | Mus musculus | 40.80 | 6 | unnamed protein product |
22 | Mus musculus | 40.80 | 2 | Gastric inhibitory polypeptide |
23 | Oncorhynchus tshawytscha | 40.40 | 1 | S78474_1 proglucagon |
24 | Bos taurus | 40.00 | 2 | PREDICTED: similar to Gastric inhibitory polypept |
25 | Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | 40.00 | 1 | VIP_MOUSE VIP peptides precursor |
26 | Rattus norvegicus | 39.70 | 4 | PREDICTED: similar to VIP peptides precursor |
27 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 39.70 | 1 | glucagon-like peptide, GLP |
28 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 39.70 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
29 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 39.30 | 2 | GLUC_CARAU Glucagon precursor |
30 | Heloderma suspectum | 39.30 | 2 | proglucagon |
31 | Arvicanthis ansorgei | 39.30 | 1 | vasoactive intestinal polypeptide |
32 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 39.30 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
33 | Heloderma horridum | 38.50 | 1 | EXE3_HELHO Exendin-3 precursor gi |
34 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 38.50 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
35 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 38.50 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
36 | Tetraodon nigroviridis | 38.10 | 3 | unnamed protein product |
37 | Ambloplites rupestris | 37.70 | 1 | proglucagon |
38 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 35.80 | 1 | GLUC2_PETMA Glucagon-2 precursor |
39 | synthetic construct | 35.40 | 1 | Homo sapiens glucagon |
40 | Heloderma suspectum, venom, Peptide, 39 aa | 35.40 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30- |
41 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 35.00 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
42 | Danio rerio | 34.70 | 1 | glucagon polyprotein |
43 | Canis lupus familiaris | 34.30 | 1 | glucagon |
44 | Contains: Glucagon-1; Glucagon-like peptide 1-1 | 34.30 | 1 | GLUC1_ONCKI Glucagon-1 precursor |
45 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 33.90 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
46 | Sus scrofa | 33.90 | 1 | glucagon |
47 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 33.10 | 1 | GLUC_LEPSP Glucagon precursor |
48 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 33.10 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gi |
49 | Gallus gallus | 33.10 | 1 | growth hormone-releasing hormone/pituitary adenyl |
50 | swine, intestines, Peptide Partial, 56 aa | 30.80 | 1 | secretin precursor, N-prosecretin, secretin-(-9 t |
51 | Shewanella sp. ANA-3 | 30.80 | 1 | catalase/peroxidase HPI |
52 | swine, small intestine, Peptide Partial, 36 aa | 30.00 | 1 | diazepam-binding inhibitor (32-86), DBI(32-86)=an |
Top-ranked sequences
organism | matching |
---|---|
N/A | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIA 89 |||||||||||||||||||||||||||#|||||+|||| Sbjct 1 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNKNNIA 37 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN 84 ||+||||||||||+|+|||+|||||||#+|||| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDFVQWLM#STKRN 32 |
Contains: Glucagon; Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 |||||||+|||||+|+|||||||||||#+| +|+ + ||| | Sbjct 1 HSQGTFTNDYSKYMDTRRAQDFVQWLM#STXXXXXXXXXXXXX-XXYADAPYISDVYS 56 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 81 |||||||||||||||+||||||+||||#+| Sbjct 1 HSQGTFTSDYSKYLDNRRAQDFIQWLM#ST 29 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN 84 ||+|||++||||||++|||||||||| #|+||| Sbjct 1 HSEGTFSNDYSKYLETRRAQDFVQWLK#NSKRN 32 |
Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 81 |||||||+|||||+|+|||||||||||#+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDFVQWLM#ST 29 |
Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 81 ||+||||||||||+|+|||+|||||||#+| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDFVQWLM#ST 29 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKR 83 ||+|||++||||||+ |+|||||+|||#| || Sbjct 1 HSEGTFSNDYSKYLEDRKAQDFVRWLM#NNKR 31 |
Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 81 ||||+|||||||||||++|+||| |||#|| Sbjct 1 HSQGSFTSDYSKYLDSKQAKDFVIWLM#NT 29 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 81 ||+|||||||||||++++|+|||+|||#| Sbjct 1 HSEGTFTSDYSKYLENKQAKDFVRWLM#NA 29 |
Xenopus laevis | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 108 |||||||||||||||||||||||||||||#||||+ +++|+ ++||||||||||||+ Sbjct 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRS-GGLSRRNADYERHAEGTFTSDVT 107 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 108 +||++||+|+| ++||+ + + |++||+# | + + ||||||||+|++ Sbjct 140 ERHAEGTYTNDVTEYLEEKATKAFIEWLI#KGK-------PKKIRYSRHAEGTFTNDMT 190 Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRH 92 ||++||||+| + ||+ + |++|| ||+#| + | ++ + | Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEFVGWLI#NGRPKRKDLLEEH 219 |
Hoplobatrachus rugulosus | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 108 |||||||||||||||||||||||||||||#|+||+ |+||+ +||||||||+|+||+ Sbjct 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NSKRS-GGISKRNVQFERHAEGTYTNDVT 107 Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFE-RHAEGTFTSD 106 ||++|||||| + ||+ + |++|| ||+# + || +| + |||+|+|||| Sbjct 134 RHAEGTFTSDMTSYLEEKAAKEFVDWLI#KGRPKRNFPDISAEEMDRRHADGSFTSD 189 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 +||++||+|+| +++|+ + |++|+ ||+# | + ++ ||||||||||++| Sbjct 95 ERHAEGTYTNDVTQFLEEKAAKEFIDWLI#KGKPKKQRLS-------RHAEGTFTSDMTS 146 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 81 |+||+ |+||||++| || + ||+|+ |++#|| Sbjct 178 DRRHADGSFTSDFNKALDIKAAQEFLDWII#NT 209 |
Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||+|||||||||||++++|+|||+|||#| || + + + |||+||||+|++| Sbjct 41 KRHSEGTFTSDYSKYLENKQAKDFVRWLM#NAKRGGSELQR------RHADGTFTNDMTS 93 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIA---KRHDEFERHAE 100 +||+ ||||+| + |||++ |+||| || # + ++| + + | +|||| Sbjct 80 RRHADGTFTNDMTSYLDAKAARDFVSWLA#RSDKSRRDGGDHLAENSEDKRHAE 132 |
Gallus gallus | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN------------------RNNIAKRH 92 |||||||||||||||||||||||||||||#+|||| | |+||| Sbjct 53 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#STKRNGQQGQEDKENDKFPDQLSSNAISKRH 112 Query 93 DEFERHAEGTFTSDVSS 109 |||||||||+|||++| Sbjct 113 SEFERHAEGTYTSDITS 129 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFE---RHAEGTFTSDV 107 +||++||+||| + ||+ + |++|+ ||+#| + |+ | | |||+||||||+ Sbjct 116 ERHAEGTYTSDITSYLEGQAAKEFIAWLV#NGRGRRDFPEKALMAEEMGRRHADGTFTSDI 175 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNI 88 +||+ |||||| +| || |++|++||+#||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEFLKWLI#NTKVTQRDL 201 |
Meleagris gallopavo | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN------------------RNNIAKRH 92 |||||||||||||||||||||||||||||#+|||| | |+||| Sbjct 53 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#STKRNGQQGQEDKENDEFPDQLSSNAISKRH 112 Query 93 DEFERHAEGTFTSDVSS 109 |||||||||+|||++| Sbjct 113 SEFERHAEGTYTSDITS 129 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFE---RHAEGTFTSDV 107 +||++||+||| + ||+ + |++|+ ||+#| + |+ | | |||+||||||+ Sbjct 116 ERHAEGTYTSDITSYLEGQAAKEFIAWLV#NGRGRRDFPEKALMAEEMGRRHADGTFTSDI 175 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNI 88 +||+ |||||| +| || |++|++||+#||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEFLKWLI#NTKVTQRDL 201 |
Canis familiaris | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN----NIAKR 91 |+++||| |||| +| | |||| ||+# | +| || +| Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNWLL#AQKGKKNDWKHNITQR 86 |
Rattus norvegicus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNN 87 |+++||| |||| +| | |||| ||+# | +|+ Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNWLL#AQKGKKND 78 |
Bos taurus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||||+ | |+ +++ |+# || |+|++ +||++ || Sbjct 80 RHADGVFTSDYSRLLGQLSAKKYLESLI#G-KRVSNSISEDQGPIKRHSDAVFT 131 |
Homo sapiens | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||+|| | |+ +++ ||# || +||++ +||++ || Sbjct 80 RHADGVFTSDFSKLLGQLSAKKYLESLM#G-KRVSSNISEDPVPVKRHSDAVFT 131 |
Xenopus tropicalis | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 108 ||||||||||||||||||||||||+||||#||||+ +++|+ ++||||||||||||+ Sbjct 51 KRHSQGTFTSDYSKYLDSRRAQDFIQWLM#NTKRS-GGLSRRNADYERHAEGTFTSDVT 107 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 108 +||++||+|+| ++||+ + |++|++||+#| | + + ||||||||+|++ Sbjct 140 ERHAEGTYTNDVTEYLEEKAAKEFIEWLI#NGK-------PKKIRYSRHAEGTFTNDMT 190 Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFE---RHAEGTFTSDV 107 ||++||||+| + ||+ + |++|| ||+# | + | ++ | | |||+|+||+|+ Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEFVGWLI#K-GRPKRNFSEAHSVEEMDRRHADGSFTNDI 236 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 82 |+||+ |+||+| +| || ||+|+ |++#||+ Sbjct 224 DRRHADGSFTNDINKVLDIIAAQEFLDWVI#NTQ 256 |
Mus musculus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN----NIAKRH 92 |+++||| |||| +| | |||| ||+# + ++ || +| Sbjct 29 RYAEGTFISDYSIAMDKIRQQDFVNWLL#AQRGKKSDWKHNITQRE 73 |
Mus musculus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN----NIAKRH 92 |+++||| |||| +| | |||| ||+# + ++ || +| Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNWLL#AQRGKKSDWKHNITQRE 87 |
Oncorhynchus tshawytscha | Query 54 SQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 | |||++||||| + | |||||||||#|+||+ +|||+||+|||||+ Sbjct 2 SXGTFSNDYSKYQEERMAQDFVQWLM#NSKRS-------GAPSKRHADGTYTSDVST 50 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 85 |||+ ||+||| | || + |+||| || #+ + | Sbjct 37 KRHADGTYTSDVSTYLQDQAAKDFVSWLK#SGRARR 71 |
Bos taurus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR----NNIAKR 91 |+++||| |||| +| | |||| ||+# | + +|| +| Sbjct 81 RYAEGTFISDYSIAMDKIRQQDFVNWLL#AQKGKKSDWIHNITQR 124 |
Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||||+ | |+ +++ |+# || ++|++ +||++ || Sbjct 80 RHADGVFTSDYSRLLGQISAKKYLESLI#G-KRISSSISEDPVPIKRHSDAVFT 131 |
Rattus norvegicus | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||||+ | |+ +++ |+# || ++|++ +||++ || Sbjct 80 RHADGVFTSDYSRLLGQISAKKYLESLI#G-KRISSSISEDPVPVKRHSDAVFT 131 |
Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWL 78 |+ ||||+| + |||++ |+||| || Sbjct 1 HADGTFTNDMTSYLDAKAARDFVSWL 26 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 82 |+ |+|||| +| ||+ |++|+ ||+#+|| Sbjct 1 HADGSFTSDINKVLDTIAAKEFLNWLI#STK 30 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||+|||++||||||++|||||||+|||#|+| | + +||||||+|||+|| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDFVEWLM#NSKSNGGSA-------KRHAEGTYTSDISS 99 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWL 78 |||++||+||| | +| + ||+|| || Sbjct 86 KRHAEGTYTSDISSFLRDQAAQNFVAWL 113 |
Heloderma suspectum | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKR------------------NRNNIAKRH 92 |||||||||||||||||+|||||||||||#|||| + | +|+ | Sbjct 51 KRHSQGTFTSDYSKYLDTRRAQDFVQWLM#NTKRSGQQGVEEREKENLLDQLSSNGLARHH 110 Query 93 DEFERHAEGTFTSDVSS 109 |+||||+| +|||+|| Sbjct 111 AEYERHADGRYTSDISS 127 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 85 +||+ | +||| | ||+ + |++|+ ||+#| + | Sbjct 114 ERHADGRYTSDISSYLEGQAAKEFIAWLV#NGRGRR 148 |
Arvicanthis ansorgei | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFT 104 ||+ | ||||||+ | |+ +++ |+# || ++| + +||++ || Sbjct 63 RHADGVFTSDYSRLLGQISAKKYLESLI#G-KRISSSILEDPVPIKRHSDAVFT 114 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||+|||++||||||++|||||||||| #|+||| | |||+||+|||||| Sbjct 50 KRHSEGTFSNDYSKYLETRRAQDFVQWLK#NSKRN--------GLFRRHADGTYTSDVSS 100 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWL 78 +||+ ||+||| | || + |+||| || Sbjct 87 RRHADGTYTSDVSSYLQDQAAKDFVSWL 114 |
Heloderma horridum | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#N 80 |||| |||||| || ++ + |++|| #| Sbjct 46 KRHSDGTFTSDLSKQMEEEAVRLFIEWLK#N 75 |
Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 || |+|||++ |||| + | |+||+ |||#|+||+ +|||+||+|||||+ Sbjct 50 KRQSEGTFSNYYSKYQEERMARDFLHWLM#NSKRS-------GAPSKRHADGTYTSDVST 101 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEF--ERHAEGTFTSDV 107 |||+ ||+||| | || + |+||| || #+ | + + + || +|+||||| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDFVSWLK#SGPARRESAEESMNGPMSRRHVDGSFTSDV 146 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 82 +|| |+|||| +| ||| |++++ |+|# +| Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEYLLWVM#TSK 166 |
Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||+|||++||||| + | |||||||||#|+||+ +|||+||+|||||+ Sbjct 50 KRHSEGTFSNDYSKYQEERMAQDFVQWLM#NSKRS-------GAPSKRHADGTYTSDVST 101 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNI--AKRHDEFERHAEGTFTSDV 107 |||+ ||+||| | || + |+||| || #+ + | + ++ || +|+||||| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDFVSWLK#SGRARRESAEESRNGPMSRRHVDGSFTSDV 146 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 82 +|| |+|||| +| ||| |++++ |+|# +| Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEYLLWVM#TSK 166 |
Tetraodon nigroviridis | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||+|||++||||||++|||||||||| #|+||| + | |||+||+|||||+ Sbjct 787 KRHSEGTFSNDYSKYLETRRAQDFVQWLK#NSKRNGS-------LFRRHADGTYTSDVSA 838 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 85 +||+ ||+||| | || + |++|| || # | | | Sbjct 825 RRHADGTYTSDVSAYLQDQAAKEFVSWL-#KTGRGR 858 |
Ambloplites rupestris | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 |||||||+||+ ||+ |+||||++|||#| | |+ |++ |||+|||| | || Sbjct 1 HSQGTFTNDYTNYLEDRQAQDFIRWLM#NNK--RSGAAEK-----RHADGTFTDDASS 50 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK-RNRNNIAKRHDEFE-RHAEGTFTSDV 107 +|||+ |||| | | + +||| | #+ + | +| + | || ||+||||+ Sbjct 36 EKRHADGTFTDDASSDFYDQAIKDFVAKLK#SGQDRREPETDRRREAFSRRHVEGSFTSDI 95 |
Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 52 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDV 107 |||||+|||||||+|| ++|+||| ||+#|||| + + +||++|+||+|+ Sbjct 43 RHSQGSFTSDYSKHLDVKQAKDFVTWLL#NTKRRGVDAQAGANLEKRHSDGSFTNDM 98 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWL 78 +|||| |+||+| + || |++|++|| Sbjct 86 EKRHSDGSFTNDMNVMLDRMSAKNFLEWL 114 |
synthetic construct | Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN---NIAKRHDEFERHAEGTFTSDV 107 +||++|||||| | ||+ + |++|+ ||+# + |+ +| + |||+|+|+ ++ Sbjct 96 ERHAEGTFTSDVSSYLEGQAAKEFIAWLV#KGRGRRDFPEEVAIVEELGRRHADGSFSDEM 155 Query 108 SS 109 ++ Sbjct 156 NT 157 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 82 +||+ |+|+ + + ||+ |+||+ ||+# || Sbjct 144 RRHADGSFSDEMNTILDNLAARDFINWLI#QTK 175 |
Heloderma suspectum, venom, Peptide, 39 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#N 80 | +|||||| || ++ + |++|| #| Sbjct 1 HGEGTFTSDLSKQMEEEAVRLFIEWLK#N 28 |
Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||+|||++||||||+ |+||+||+|||#| | |+ +|++ |||+||||||||| Sbjct 51 KRHSEGTFSNDYSKYLEDRKAQEFVRWLM#NNK--RSGVAEK-----RHADGTFTSDVSS 102 Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWL 78 +|||+ |||||| | || + +||| | Sbjct 88 EKRHADGTFTSDVSSYLKDQAIKDFVDRL 116 |
Danio rerio | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||+|||++||||||++|||||||||||#| ||| ++ +||||||+|||||| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDFVQWLM#NAKRNGGSV-------KRHAEGTYTSDVSS 99 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWL 78 |||++||+||| | || + || || | Sbjct 86 KRHAEGTYTSDVSSYLQDQAAQRFVARL 113 |
Canis lupus familiaris | Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||||||||||||||||||||||||||||#|||||+|||||||||||||||||||||||| Sbjct 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNKNNIAKRHDEFERHAEGTFTSDVSS 109 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN---NIAKRHDEFERHAEGTFTSDV 107 +||++|||||| | ||+ + |++|+ ||+# + |+ +| + |||+|+|+ ++ Sbjct 96 ERHAEGTFTSDVSSYLEGQAAKEFIAWLV#KGRGRRDFPEEVAIVEEFRRRHADGSFSDEM 155 Query 108 SS 109 ++ Sbjct 156 NT 157 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 82 +||+ |+|+ + + ||+ +||+ ||+# || Sbjct 144 RRHADGSFSDEMNTVLDTLATRDFINWLL#QTK 175 |
Contains: Glucagon-1; Glucagon-like peptide 1-1 | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||+|||++||||| + | |||||||||#|+ ||+||+||+||+ Sbjct 1 HSEGTFSNDYSKYQEERMAQDFVQWLM#NSXXXXXX--------XXHADGTYTSNVST 49 Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWL 78 |+ ||+||+ | || + |+||| || Sbjct 38 HADGTYTSNVSTYLQDQAAKDFVSWL 63 |
Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN 86 |+ || ||| | +|+ + ++|+ ||+#+ + | Sbjct 1 HADGTLTSDISSFLEKQATKEFIAWLV#SGRGRRQ 34 |
Sus scrofa | Query 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 ||||||||||||||||||||||||||||||#|||||+|||||||||||||||||||||||| Sbjct 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNKNNIAKRHDEFERHAEGTFTSDVSS 109 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN---NIAKRHDEFERHAEGTFTSDV 107 +||++|||||| | ||+ + |++|+ ||+# + |+ + + |||+|+|+ ++ Sbjct 96 ERHAEGTFTSDVSSYLEGQAAKEFIAWLV#KGRGRRDFPEEVTIVEELRRRHADGSFSDEM 155 Query 108 SS 109 ++ Sbjct 156 NT 157 Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 82 +||+ |+|+ + + ||+ +||+ ||+#+|| Sbjct 144 RRHADGSFSDEMNTVLDNLATRDFINWLL#HTK 175 |
Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 109 |||||||+|||||||+|||||||||||#+|||+ | ||+||+|||||| Sbjct 1 HSQGTFTNDYSKYLDTRRAQDFVQWLM#STKRS-GGITXXXXXXXXHADGTYTSDVSS 56 Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWL 78 |+ ||+||| | || + |+ || || Sbjct 45 HADGTYTSDVSSYLQDQAAKKFVTWL 70 |
Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 56 GTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNN 87 ||+||| | || + |++|| || # | | | + Sbjct 3 GTYTSDVSSYLQDQAAKEFVSWL-#KTGRGRRD 33 |
Gallus gallus | Query 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEF-ERHAEGTFTSDVS 108 |||+ | |+ | | | |++++ ||# || + + + +|| +| || | Sbjct 81 KRHADGIFSKAYRKLLGQLSARNYLHSLM#-AKRVGSGLGDEAEPLSKRHIDGIFTDSYS 138 |
swine, intestines, Peptide Partial, 56 aa | Query 53 HSQGTFTSDYSKYLDSRRAQDFVQWLM# 79 || |||||+ |+ || | | +| |+# Sbjct 30 HSDGTFTSELSRLRDSARLQRLLQGLV# 56 |
Shewanella sp. ANA-3 | Query 65 YLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 108 ++ ++ +||+ # + | + ||+ +||| ||||++ Sbjct 340 WVQTKSPAGHIQWIP#KDGKGANLVPDAHDKSKRHAPIMFTSDIA 383 |
swine, small intestine, Peptide Partial, 36 aa | Query 59 TSDYSKYLDSRRAQDFVQWLM#NTKRNRNN 87 |||| +| | |||| ||+# | +++ Sbjct 1 ISDYSIAMDKIRQQDFVNWLL#AQKGKKSD 29 |
* References
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