SB0060 : Insulin
[ CaMP Format ]
* Basic Information
| Organism | Bos taurus (cattle) |
| Protein Names | insulin precursor [Bos taurus]; insulin precursor; proinsulin; Insulin; Insulin B chain; Insulin A chain |
| Gene Names | INS; insulin |
| Gene Locus | 29; chromosome 29 |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| NP_776351 | NM_173926 | 280829 | P01317 | N/A | N/A | N/A | bta:280829 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 105 aa
Average Mass: 11.393 kDa
Monoisotopic Mass: 11.386 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| --- cleavage 29 --- | ||||
| Nematode insulin-related peptide beta type 1. | 29 | 45 | 2.0 | 0.2 |
| --- cleavage 29 (inside Nematode insulin-related peptide beta type 29..45) --- | ||||
| --- cleavage 32 (inside Nematode insulin-related peptide beta type 29..45) --- | ||||
| --- cleavage 37 (inside Nematode insulin-related peptide beta type 29..45) --- | ||||
| --- cleavage 40 (inside Nematode insulin-related peptide beta type 29..45) --- | ||||
| --- cleavage 50 --- | ||||
| Nematode insulin-related peptide beta type 2. | 85 | 97 | 27.0 | 0.4 |
3. Sequence Information
Fasta Sequence: SB0060.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Known Structures in PDB: 1APH (X-ray; 200 A; A=85-105, B=25-54), 1BPH (X-ray; 200 A; A=85-105, B=25-54), 1CPH (X-ray; 190 A; A=85-105, B=25-54), 1DPH (X-ray; 190 A; A=85-105, B=25-54), 1HO0 (NMR; -; A=25-54), 1PID (X-ray; 130 A; A/C=85-105, B/D=25-49), 2A3G (X-ray; 225 A; A/C=85-105, B/D=25-54), 2BN1 (X-ray; 140 A; A=85-105, B=25-54), 2BN3 (X-ray; 140 A; A=85-105, B=25-54), 2INS (X-ray; 250 A; A/C=85-105, B/D=26-54), 2ZP6 (X-ray; 256 A; A/C=85-105, B/D=25-54), 3W14 (X-ray; 440 A; A/I=85-105, B/J=25-54), 4BS3 (X-ray; 230 A; A=85-105, B=25-54), 4E7T (X-ray; 140 A; A/C=85-105, B/D=25-54), 4E7U (X-ray; 130 A; A/C=85-105, B/D=25-54), 4E7V (X-ray; 180 A; 1/3/5/A/C/E/G/I/K/M/O/Q/S/U/W/Y=85-105, 2/4/6/B/D/F/H/J/L/N/P/R/T/V/X/Z=25-54), 4I5Y (X-ray; 180 A; A=85-105, B=25-54), 4I5Z (X-ray; 180 A; A=85-105, B=25-54), 4IDW (X-ray; 270 A; A/C=85-105, B/D=25-54), 4IHN (X-ray; 116 A; A=85-105, B=25-54), 4M4F (X-ray; 190 A; A/C=85-105, B/D=25-54), 4M4H (X-ray; 190 A; A/C=85-105, B/D=25-54), 4M4I (X-ray; 190 A; A/C=85-105, B/D=25-54), 4M4J (X-ray; 190 A; A/C=85-105, B/D=25-54), 4M4L (X-ray; 145 A; A/C=85-105, B/D=25-54), 4M4M (X-ray; 150 A; A/C=85-105, B/D=25-54)
* Cleavage Information
5 [sites] cleaved by Calpain 11
Source Reference: [PubMed ID: 479144] Ishiura S, Sugita H, Suzuki K, Imahori K, Studies of a calcium-activated neutral protease from chicken skeletal muscle. II. Substrate specificity. J Biochem. 1979 Aug;86(2):579-81.
Cleavage sites (±10aa)
[Site 1] PPARAFVNQH29-LCGSHLVEAL
His29 
Leu
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Pro20 | Pro21 | Ala22 | Arg23 | Ala24 | Phe25 | Val26 | Asn27 | Gln28 | His29 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Leu30 | Cys31 | Gly32 | Ser33 | His34 | Leu35 | Val36 | Glu37 | Ala38 | Leu39 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| MALWTRLRPLLALLALWPPPPARAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVE |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Bos taurus | 122.00 | 1 | proinsulin precursor |
| 2 | Contains: Insulin B chain; Insulin A chain | 94.40 | 7 | INS_SPETR Insulin precursor |
| 3 | Pan troglodytes | 92.80 | 1 | proinsulin precursor |
| 4 | Homo sapiens | 92.40 | 2 | proinsulin precursor |
| 5 | Felis catus | 92.40 | 2 | proinsulin precursor |
| 6 | synthetic construct | 92.40 | 2 | Homo sapiens insulin |
| 7 | N/A | 92.00 | 76 | insulin |
| 8 | Contains: Insulin B chain; Insulin A chain | 92.00 | 18 | INS_CRILO Insulin precursor |
| 9 | Gallus gallus | 90.90 | 2 | proinsulin precursor |
| 10 | Rattus norvegicus | 90.50 | 2 | insulin 1 |
| 11 | Mus musculus | 87.00 | 3 | insulin II |
| 12 | Canis familiaris | 86.70 | 4 | PREDICTED: similar to Insulin precursor |
| 13 | Sus scrofa | 84.70 | 2 | insulin |
| 14 | Oryctolagus cuniculus | 84.30 | 1 | insulin |
| 15 | Columba livia | 81.60 | 1 | preproinsulin |
| 16 | Xenopus laevis | 80.90 | 2 | insulin I |
| 17 | Rana pipiens | 77.80 | 1 | AF227187_1 preproinsulin |
| 18 | Bubalus bubalis | 77.00 | 1 | proinsulin |
| 19 | Passer domesticus | 75.10 | 1 | preproinsulin |
| 20 | Aptenodytes forsteri | 74.30 | 1 | preproinsulin |
| 21 | Turdus merula | 73.90 | 1 | preproinsulin |
| 22 | Phaethon aethereus | 73.90 | 1 | preproinsulin |
| 23 | Struthio camelus | 73.90 | 1 | preproinsulin |
| 24 | Dromaius novaehollandiae | 73.60 | 1 | preproinsulin |
| 25 | Ciconia ciconia | 72.80 | 1 | preproinsulin |
| 26 | Pica pica | 72.80 | 1 | preproinsulin |
| 27 | Strix aluco | 72.40 | 1 | preproinsulin |
| 28 | Gallinula chloropus | 72.40 | 1 | preproinsulin |
| 29 | Sula sula | 72.40 | 1 | preproinsulin |
| 30 | Falco tinnunculus | 72.00 | 1 | preproinsulin |
| 31 | Anas crecca | 72.00 | 1 | preproinsulin |
| 32 | Rhea americana | 70.50 | 1 | preproinsulin |
| 33 | synthetic construct | 70.50 | 1 | proinsulin-like protein BKRA |
| 34 | Hiodon alosoides | 66.20 | 1 | preproinsulin |
| 35 | Chitala chitala | 65.90 | 1 | preproinsulin |
| 36 | Osteoglossum bicirrhosum | 63.50 | 1 | preproinsulin |
| 37 | Tetraodon nigroviridis | 62.80 | 2 | unnamed protein product |
| 38 | Chinchilla brevicaudata | 62.40 | 1 | insulin |
| 39 | Dasyprocta punctata | 62.40 | 1 | insulin |
| 40 | Gorilla gorilla | 61.60 | 1 | insulin |
| 41 | Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | 61.20 | 1 | insulin B chain |
| 42 | Danio rerio | 60.80 | 3 | preproinsulin b |
| 43 | Gnathonemus petersii | 60.10 | 1 | preproinsulin |
| 44 | thr(B27)->pro,Pro(B28)- >thr | 60.10 | 1 | B Chain B, Solution Structure Of The Monomeric |
| 45 | phe(B25) | 59.30 | 1 | B Chain B, Solution Structure Of The Superactive |
| 46 | Catostomus commersoni | 59.30 | 1 | preproinsulin |
| 47 | Catla catla | 58.20 | 1 | AF373021_1 preproinsulin |
| 48 | Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | 58.20 | 1 | insulin B-chain |
| 49 | Oncorhynchus keta | 57.80 | 1 | preproinsulin |
| 50 | Ambloplites rupestris | 57.00 | 1 | preproinsulin |
| 51 | Dolichotis patagonum | 56.60 | 1 | insulin |
| 52 | Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | 56.60 | 1 | insulin B chain |
| 53 | Contains: Insulin B chain; Insulin A chain | 56.60 | 1 | INS_CALMI Insulin |
| 54 | d-Alab26 | 56.60 | 1 | B Chain B, |
| 55 | Hydrochaeris hydrochaeris | 55.50 | 1 | insulin |
| 56 | Lagidium viscacia | 54.70 | 1 | insulin |
| 57 | Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | 54.70 | 1 | insulin B-chain |
| 58 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | 54.30 | 1 | insulin B-chain |
| 59 | Galea musteloides | 48.10 | 1 | insulin |
| 60 | Cavia porcellus | 47.80 | 1 | insulin |
| 61 | Microcavia niata | 47.40 | 1 | insulin |
| 62 | Ctenomys leucodon | 45.10 | 1 | insulin |
| 63 | Ctenomys robore | 45.10 | 1 | insulin |
| 64 | Octodontomys gliroides | 42.40 | 1 | insulin |
| 65 | Spalacopus cyanus | 42.00 | 1 | insulin |
| 66 | Tympanoctomys barrerae | 42.00 | 1 | insulin |
| 67 | Octomys mimax | 42.00 | 1 | insulin |
| 68 | Rhabdosargus sarba | 41.60 | 1 | insulin-like growth factor I |
| 69 | Octodon degus | 41.60 | 1 | insulin |
| 70 | Symphysodon aequifasciata | 41.20 | 1 | insulin-like growth factor-1 |
Top-ranked sequences
| organism | matching |
|---|---|
| Bos taurus | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |
| Contains: Insulin B chain; Insulin A chain | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ||||||| |||||||| | ||+||||||#||||||||||||||||||||||||+||||| Sbjct 1 MALWTRLLPLLALLALLGPDPAQAFVNQH#LCGSHLVEALYLVCGERGFFYTPKSRREVE 59 |
| Pan troglodytes | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| || ||| ||||| | || ||||||#|||||||||||||||||||||||| ||| | Sbjct 1 MALWMRLLPLLVLLALWGPDPASAFVNQH#LCGSHLVEALYLVCGERGFFYTPKTRREAE 59 |
| Homo sapiens | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| || ||||||||| | || ||||||#|||||||||||||||||||||||| ||| | Sbjct 1 MALWMRLLPLLALLALWGPDPAAAFVNQH#LCGSHLVEALYLVCGERGFFYTPKTRREAE 59 |
| Felis catus | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 || |||| ||||||+|| | | |||||||#|||||||||||||||||||||||||||| | Sbjct 1 MAPWTRLLPLLALLSLWIPAPTRAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREAE 59 |
| synthetic construct | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| || ||||||||| | || ||||||#|||||||||||||||||||||||| ||| | Sbjct 1 MALWMRLLPLLALLALWGPDPAAAFVNQH#LCGSHLVEALYLVCGERGFFYTPKTRREAE 59 |
| N/A | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| || ||||||||| | || ||||||#|||||||||||||||||||||||| ||| | Sbjct 1 MALWMRLLPLLALLALWGPDPAAAFVNQH#LCGSHLVEALYLVCGERGFFYTPKTRREAE 59 |
| Contains: Insulin B chain; Insulin A chain | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | || || ||| || || | ||+||||||#||||||||||||||||||||||||+|| || Sbjct 1 MTLWMRLLPLLTLLVLWEPNPAQAFVNQH#LCGSHLVEALYLVCGERGFFYTPKSRRGVE 59 |
| Gallus gallus | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| | |||||| | + | |||#|||||||||||||||||||||+|||||+|| Sbjct 1 MALWIRSLPLLALLVFSGPGTSYAAANQH#LCGSHLVEALYLVCGERGFFYSPKARRDVE 59 |
| Rattus norvegicus | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| | |||||| || | ||+||| ||#||| ||||||||||||||||||||+||||| Sbjct 1 MALWMRFLPLLALLVLWEPKPAQAFVKQH#LCGPHLVEALYLVCGERGFFYTPKSRREVE 59 |
| Mus musculus | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| | |||||| || | +||| ||#||||||||||||||||||||||| +||||| Sbjct 1 MALWMRFLPLLALLFLWESHPTQAFVKQH#LCGSHLVEALYLVCGERGFFYTPMSRREVE 59 |
| Canis familiaris | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| || ||||||||| | | |||||||#|||||||||||||||||||||||||||||| Sbjct 1 MALWMRLLPLLALLALWAPAPTRAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |
| Sus scrofa | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ||||||| ||||||||| | ||+||||||#|||||||||||||||||||||||||||| | Sbjct 1 MALWTRLLPLLALLALWAPAPAQAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREAE 59 |
| Oryctolagus cuniculus | Query 20 PPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ||+||||||#||||||||||||||||||||||||+||||| Sbjct 20 DPAQAFVNQH#LCGSHLVEALYLVCGERGFFYTPKSRREVE 59 |
| Columba livia | Query 9 PLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||||| | + | |||#|||||||||||||||||||||+|||||+|| Sbjct 2 PLLALLVFSGPGTSYAAANQH#LCGSHLVEALYLVCGERGFFYSPKARRDVE 52 |
| Xenopus laevis | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| + ||+ +| + | | ||||#|||||||||||||||+||||| || +|++| Sbjct 1 MALWMQCLPLVLVL-FFSTPNTEALVNQH#LCGSHLVEALYLVCGDRGFFYYPKVKRDME 58 |
| Rana pipiens | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| + + ||+|+ | + | ||+#|||||||||||+|||+|||||+|++||++| Sbjct 1 MALWIQCLHIAVLLSLFTPT-LKTFDNQY#LCGSHLVEALYMVCGDRGFFYSPRSRRDLE 58 |
| Bubalus bubalis | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||||#|||||||||||||||||||||||||||||| Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |
| Passer domesticus | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | + | ||||#||||||||||||||||||||| |||||+|| Sbjct 12 PGSSHAAVNQH#LCGSHLVEALYLVCGERGFFYQPKARRDVE 52 |
| Aptenodytes forsteri | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | + | |||#|||||||||||||||||||||+|||||+|| Sbjct 12 PGTSHAAANQH#LCGSHLVEALYLVCGERGFFYSPKARRDVE 52 |
| Turdus merula | Query 22 ARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ++| ||||#||||||||||||||||||||| |||||+|| Sbjct 15 SQAAVNQH#LCGSHLVEALYLVCGERGFFYQPKARRDVE 52 |
| Phaethon aethereus | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | + | |||#|||||||||||||||||||||+|||||++| Sbjct 12 PGTSHAAANQH#LCGSHLVEALYLVCGERGFFYSPKARRDIE 52 |
| Struthio camelus | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | + | |||#|||||||||||||||||||||+|||||++| Sbjct 12 PGTSHAAANQH#LCGSHLVEALYLVCGERGFFYSPKARRDIE 52 |
| Dromaius novaehollandiae | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | ++| |||#|||||||||||||||||||||+|||||+ | Sbjct 12 PGTSQAAANQH#LCGSHLVEALYLVCGERGFFYSPKARRDAE 52 |
| Ciconia ciconia | Query 22 ARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 + | |||#|||||||||||||||||||||+|||||+|| Sbjct 15 SHAAANQH#LCGSHLVEALYLVCGERGFFYSPKARRDVE 52 |
| Pica pica | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | + | |+||#||||||||||||||||||||| |||||++| Sbjct 12 PGSSHAAVSQH#LCGSHLVEALYLVCGERGFFYQPKARRDIE 52 |
| Strix aluco | Query 22 ARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 + | |||#|||||||||||||||||||||+|||||++| Sbjct 15 SHAAANQH#LCGSHLVEALYLVCGERGFFYSPKARRDIE 52 |
| Gallinula chloropus | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | + | ||#|||||||||||||||||||||+|||||+|| Sbjct 12 PGTSHAVATQH#LCGSHLVEALYLVCGERGFFYSPKARRDVE 52 |
| Sula sula | Query 22 ARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 + | |||#|||||||||||||||||||||+|||||++| Sbjct 15 SHAAANQH#LCGSHLVEALYLVCGERGFFYSPKARRDIE 52 |
| Falco tinnunculus | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | + | ||#|||||||||||||||||||||+|||||+|| Sbjct 12 PGTSHAAATQH#LCGSHLVEALYLVCGERGFFYSPKARRDVE 52 |
| Anas crecca | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | + | |||#|||||||||||||||||||||+|| ||+|| Sbjct 12 PGISHAAANQH#LCGSHLVEALYLVCGERGFFYSPKTRRDVE 52 |
| Rhea americana | Query 19 PPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | + | |||#|||||||||||||| ||||||+|||||++| Sbjct 12 PGSSHAAANQH#LCGSHLVEALYLVCRERGFFYSPKARRDIE 52 |
| synthetic construct | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPKARREV 58 |||||#|||||||||||||||||||||||| +| + Sbjct 2 FVNQH#LCGSHLVEALYLVCGERGFFYTPKTKRGI 35 |
| Hiodon alosoides | Query 20 PPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 | |++ +||#|||||||+|||+||||+|||| || +|+|+ Sbjct 19 PGAQSASSQH#LCGSHLVDALYMVCGEKGFFYQPKTKRDVD 58 |
| Chitala chitala | Query 20 PPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPK-ARREVE 59 | | | |||#||||||||||||||||||||| || +|+ | Sbjct 19 PGANAASNQH#LCGSHLVEALYLVCGERGFFYNPKMDKRDAE 59 |
| Osteoglossum bicirrhosum | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ||+| + ||| || | | | + +| #|||||||+|||+|||+|||||+||+||| | Sbjct 1 MAIWLQAFPLLVLLVLSSSPGAESSSSQR#LCGSHLVDALYMVCGDRGFFYSPKSRREAE 59 |
| Tetraodon nigroviridis | Query 2 ALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ||| + +| |+ + | ||#|||||||+|||||||+||||| || |+|+ Sbjct 3 ALWLQSVSVLLLMVVSSPGSQAMAPPQH#LCGSHLVDALYLVCGDRGFFYNPK--RDVD 58 |
| Chinchilla brevicaudata | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPKA 54 |||+|#|||||||+|||||||+||||||| | Sbjct 1 FVNKH#LCGSHLVDALYLVCGDRGFFYTPMA 30 |
| Dasyprocta punctata | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPK 53 |||||#|||||||||||+ ||++||||||| Sbjct 1 FVNQH#LCGSHLVEALYMACGDKGFFYTPK 29 |
| Gorilla gorilla | Query 31 CGSHLVEALYLVCGERGFFYTPKARREVE 59 ||||||||||||||||||||||| ||| | Sbjct 1 CGSHLVEALYLVCGERGFFYTPKTRREAE 29 |
| Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | Query 27 NQH#LCGSHLVEALYLVCGERGFFYTPK 53 |||#|||||||||||||||||||||+|| Sbjct 3 NQH#LCGSHLVEALYLVCGERGFFYSPK 29 |
| Danio rerio | Query 7 LRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |+ + +| | | +++ +||#|||| ||+||||||| |||||| + ||++| Sbjct 5 LQASVLILLLASLPGSQSSPSQH#LCGSSLVDALYLVCGPRGFFYTNRGRRDLE 57 |
| Gnathonemus petersii | Query 28 QH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ||#||||||||||+|||||||||+ | +|+|+ Sbjct 4 QH#LCGSHLVEALFLVCGERGFFFNPDTKRDVD 35 |
| thr(B27)->pro,Pro(B28)- >thr | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPKA 54 |||||#||||||||||||||||||||| | Sbjct 1 FVNQH#LCGSHLVEALYLVCGERGFFYPTKT 30 |
| phe(B25) | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPKA 54 |||||#|||||||||||||||||| ||||| Sbjct 1 FVNQH#LCGSHLVEALYLVCGERG-FYTPKT 29 |
| Catostomus commersoni | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ||+| + || |||+ | ||#|||||||+||||||| |||| || |+|+ Sbjct 1 MAVWLQAGALLFLLAV-SGVNANGVAPQH#LCGSHLVDALYLVCGPTGFFYNPK--RDVD 56 |
| Catla catla | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ||+| + || |||+ | ||#|||||||+||||||| |||| || |+|+ Sbjct 1 MAVWLQAGALLFLLAV-SSVNANPGAPQH#LCGSHLVDALYLVCGPTGFFYNPK--RDVD 56 |
| Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | Query 26 VNQH#LCGSHLVEALYLVCGERGFFYTPK 53 ||+#|||||||||||||||+|||||+|| Sbjct 2 TNQY#LCGSHLVEALYLVCGDRGFFYSPK 29 |
| Oncorhynchus keta | Query 1 MALWTRLRPLLALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 |||| + || |||| | | | ||#||| |||+||||||||+||||||| |+|+ Sbjct 1 MALWLQAASLLVLLALSPGVDAAA--AQH#LCGLHLVDALYLVCGEKGFFYTPK--RDVD 55 |
| Ambloplites rupestris | Query 28 QH#LCGSHLVEALYLVCGERGFFYTPKARREVE 59 ||#|||||||+|||||||+||||| || |+|+ Sbjct 4 QH#LCGSHLVDALYLVCGDRGFFYNPK--RDVD 33 |
| Dolichotis patagonum | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPK 53 |||+|#|||||||+||| ||+||||| || Sbjct 1 FVNRH#LCGSHLVDALYSACGDRGFFYIPK 29 |
| Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPK 53 | |||#||||||||||||||||+||+| |+ Sbjct 1 FPNQH#LCGSHLVEALYLVCGEKGFYYIPR 29 |
| Contains: Insulin B chain; Insulin A chain | Query 28 QH#LCGSHLVEALYLVCGERGFFYTPKARREV 58 | #|||||||+||| |||||||||+|| |+| Sbjct 4 QR#LCGSHLVDALYFVCGERGFFYSPKQIRDV 34 |
| d-Alab26 | Query 25 FVNQH#LCGSHLVEALYLVCGERGFF 49 |||||#|||||||||||||||||||| Query 25 FVNQH#LCGSHLVEALYLVCGERGFF 49 |
| Hydrochaeris hydrochaeris | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPK 53 |+|+|#|||||||+||| ||++|||| || Sbjct 1 FINRH#LCGSHLVDALYSACGDKGFFYVPK 29 |
| Lagidium viscacia | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTP 52 ||+|#|||||||||||+|| ++|||||| Sbjct 1 IVNKH#LCGSHLVEALYMVCRDKGFFYTP 28 |
| Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | Query 27 NQH#LCGSHLVEALYLVCGERGFFYTPK 53 |#|||||||||||+|||+||||||| Sbjct 8 GTH#LCGSHLVEALYVVCGDRGFFYTPS 34 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | Query 28 QH#LCGSHLVEALYLVCGERGFFYTPK 53 ||#|||||||+|||||||+||||| |+ Sbjct 5 QH#LCGSHLVDALYLVCGDRGFFYNPR 30 |
| Galea musteloides | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPK 53 | |+|#||||+||+|||+|| ++||| || Sbjct 1 FFNRH#LCGSNLVDALYVVCKDKGFFSMPK 29 |
| Cavia porcellus | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPK 53 ||++|#||||+||| || || + |||| || Sbjct 1 FVSRH#LCGSNLVETLYSVCQDDGFFYIPK 29 |
| Microcavia niata | Query 25 FVNQH#LCGSHLVEALYLVCGERGFFYTPK 53 |||+|#||||+||| || || ++||| || Sbjct 1 FVNRH#LCGSNLVETLYEVCRDKGFFSIPK 29 |
| Ctenomys leucodon | Query 25 FVNQH#LCGSHLVEALYLVCGERGFF 49 + +||#|||||||||||+ || ||+ Sbjct 1 YASQH#LCGSHLVEALYMTCGHNGFY 25 |
| Ctenomys robore | Query 25 FVNQH#LCGSHLVEALYLVCGERGFF 49 + +||#|||||||||||+ || ||+ Sbjct 1 YASQH#LCGSHLVEALYMTCGHNGFY 25 |
| Octodontomys gliroides | Query 25 FVNQH#LCGSHLVEALYLVCGERGFF 49 + +||#||||+||||||+ || ||+ Sbjct 1 YSSQH#LCGSNLVEALYMTCGHNGFY 25 |
| Spalacopus cyanus | Query 25 FVNQH#LCGSHLVEALYLVCGERGFF 49 + +||#||||+||||||+ || ||+ Sbjct 1 YSSQH#LCGSNLVEALYMTCGRSGFY 25 |
| Tympanoctomys barrerae | Query 25 FVNQH#LCGSHLVEALYLVCGERGFF 49 + +||#||||+||||||+ || ||+ Sbjct 1 YSSQH#LCGSNLVEALYMTCGHSGFY 25 |
| Octomys mimax | Query 25 FVNQH#LCGSHLVEALYLVCGERGFF 49 + +||#||||+||||||+ || ||+ Sbjct 1 YSSQH#LCGSNLVEALYMTCGHSGFY 25 |
| Rhabdosargus sarba | Query 11 LALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFF-----YTPKARR 56 | | | | | + #|||+ ||+ | |||||||+ | | ||| Sbjct 2 LLLCVLTLTPTATGASPET#LCGAELVDTLQFVCGERGFYFSKPGYGPNARR 52 |
| Octodon degus | Query 25 FVNQH#LCGSHLVEALYLVCGERGFF 49 + +||#||||+||||||+ || ||+ Sbjct 1 YSSQH#LCGSNLVEALYMTCGRSGFY 25 |
| Symphysodon aequifasciata | Query 11 LALLALWPPPPARAFVNQH#LCGSHLVEALYLVCGERGFF-----YTPKARR 56 | | | | | + #|||+ ||+ | |||||||+ | | ||| Sbjct 5 LVLCVLTLTPTATGAGPET#LCGAELVDTLQFVCGERGFYFNKPGYGPSARR 55 |
[Site 2] RAFVNQHLCG32-SHLVEALYLV
Gly32 Ser
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Arg23 | Ala24 | Phe25 | Val26 | Asn27 | Gln28 | His29 | Leu30 | Cys31 | Gly32 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser33 | His34 | Leu35 | Val36 | Glu37 | Ala38 | Leu39 | Tyr40 | Leu41 | Val42 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LWTRLRPLLALLALWPPPPARAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQ |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Bos taurus | 124.00 | 1 | proinsulin precursor |
| 2 | Contains: Insulin B chain; Insulin A chain | 93.20 | 18 | INS_CRILO Insulin precursor |
| 3 | Contains: Insulin B chain; Insulin A chain | 90.90 | 7 | INS_SPETR Insulin precursor |
| 4 | Rattus norvegicus | 90.90 | 2 | insulin 2 |
| 5 | Felis catus | 90.10 | 2 | proinsulin precursor |
| 6 | Pan troglodytes | 89.40 | 1 | proinsulin precursor |
| 7 | Gallus gallus | 89.00 | 2 | proinsulin precursor |
| 8 | synthetic construct | 89.00 | 2 | Homo sapiens insulin |
| 9 | Homo sapiens | 89.00 | 2 | proinsulin precursor |
| 10 | N/A | 88.20 | 76 | insulin |
| 11 | Mus musculus | 87.40 | 3 | insulin II |
| 12 | Sus scrofa | 85.50 | 2 | insulin |
| 13 | Canis familiaris | 84.00 | 4 | PREDICTED: similar to Insulin precursor |
| 14 | Oryctolagus cuniculus | 84.00 | 1 | insulin |
| 15 | Bubalus bubalis | 83.60 | 1 | proinsulin |
| 16 | Columba livia | 83.20 | 1 | preproinsulin |
| 17 | Xenopus laevis | 78.60 | 2 | insulin-like growth factor 2 |
| 18 | Passer domesticus | 76.30 | 1 | preproinsulin |
| 19 | Rana pipiens | 75.90 | 1 | AF227187_1 preproinsulin |
| 20 | Aptenodytes forsteri | 75.50 | 1 | preproinsulin |
| 21 | Phaethon aethereus | 75.10 | 1 | preproinsulin |
| 22 | Struthio camelus | 75.10 | 1 | preproinsulin |
| 23 | Turdus merula | 75.10 | 1 | preproinsulin |
| 24 | Dromaius novaehollandiae | 74.70 | 1 | preproinsulin |
| 25 | Pica pica | 73.90 | 1 | preproinsulin |
| 26 | Ciconia ciconia | 73.90 | 1 | preproinsulin |
| 27 | Sula sula | 73.60 | 1 | preproinsulin |
| 28 | Gallinula chloropus | 73.60 | 1 | preproinsulin |
| 29 | Strix aluco | 73.60 | 1 | preproinsulin |
| 30 | Falco tinnunculus | 73.20 | 1 | preproinsulin |
| 31 | Anas crecca | 73.20 | 1 | preproinsulin |
| 32 | Rhea americana | 72.00 | 1 | preproinsulin |
| 33 | synthetic construct | 70.10 | 1 | proinsulin-like protein BKRA |
| 34 | Hiodon alosoides | 65.90 | 1 | preproinsulin |
| 35 | Chitala chitala | 65.50 | 1 | preproinsulin |
| 36 | Chinchilla brevicaudata | 62.40 | 1 | insulin |
| 37 | Dasyprocta punctata | 62.00 | 1 | insulin |
| 38 | Gorilla gorilla | 61.60 | 1 | insulin |
| 39 | Tetraodon nigroviridis | 60.80 | 2 | unnamed protein product |
| 40 | Osteoglossum bicirrhosum | 60.80 | 1 | preproinsulin |
| 41 | Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | 60.80 | 1 | insulin B chain |
| 42 | Danio rerio | 60.10 | 3 | preproinsulin b |
| 43 | Gnathonemus petersii | 60.10 | 1 | preproinsulin |
| 44 | thr(B27)->pro,Pro(B28)- >thr | 60.10 | 1 | B Chain B, Solution Structure Of The Monomeric |
| 45 | phe(B25) | 58.90 | 1 | B Chain B, Solution Structure Of The Superactive |
| 46 | Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | 57.80 | 1 | insulin B-chain |
| 47 | Oncorhynchus keta | 57.00 | 1 | preproinsulin |
| 48 | Ambloplites rupestris | 56.60 | 1 | preproinsulin |
| 49 | Dolichotis patagonum | 56.20 | 1 | insulin |
| 50 | d-Alab26 | 56.20 | 1 | B Chain B, |
| 51 | Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | 56.20 | 1 | insulin B chain |
| 52 | Contains: Insulin B chain; Insulin A chain | 56.20 | 1 | INS_CALMI Insulin |
| 53 | Catostomus commersoni | 55.50 | 1 | preproinsulin |
| 54 | Hydrochaeris hydrochaeris | 55.10 | 1 | insulin |
| 55 | Lagidium viscacia | 54.70 | 1 | insulin |
| 56 | Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | 54.30 | 1 | insulin B-chain |
| 57 | Catla catla | 54.30 | 1 | AF373021_1 preproinsulin |
| 58 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | 53.90 | 1 | insulin B-chain |
| 59 | Galea musteloides | 48.10 | 1 | insulin |
| 60 | Cavia porcellus | 47.40 | 1 | insulin |
| 61 | Microcavia niata | 47.00 | 1 | insulin |
| 62 | Ctenomys leucodon | 44.70 | 1 | insulin |
| 63 | Ctenomys robore | 44.70 | 1 | insulin |
| 64 | Octodontomys gliroides | 42.00 | 1 | insulin |
| 65 | Spalacopus cyanus | 42.00 | 1 | insulin |
| 66 | Tympanoctomys barrerae | 42.00 | 1 | insulin |
| 67 | Octodon degus | 41.60 | 1 | insulin |
| 68 | Octomys mimax | 41.60 | 1 | insulin |
| 69 | Rhabdosargus sarba | 41.20 | 1 | insulin-like growth factor I |
| 70 | Symphysodon aequifasciata | 41.20 | 1 | insulin-like growth factor-1 |
Top-ranked sequences
| organism | matching |
|---|---|
| Bos taurus | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 |
| Contains: Insulin B chain; Insulin A chain | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 || || ||| || || | ||+|||||||||#|||||||||||||||||||||+|| || || Sbjct 3 LWMRLLPLLTLLVLWEPNPAQAFVNQHLCG#SHLVEALYLVCGERGFFYTPKSRRGVEDPQ 62 |
| Contains: Insulin B chain; Insulin A chain | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 ||||| |||||||| | ||+|||||||||#|||||||||||||||||||||+||||| | Sbjct 3 LWTRLLPLLALLALLGPDPAQAFVNQHLCG#SHLVEALYLVCGERGFFYTPKSRREVEEQQ 62 |
| Rattus norvegicus | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 || | |||||| || | ||+||| |||||#|||||||||||||||||||| +||||| || Sbjct 3 LWIRFLPLLALLILWEPRPAQAFVKQHLCG#SHLVEALYLVCGERGFFYTPMSRREVEDPQ 62 |
| Felis catus | Query 4 WTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 |||| ||||||+|| | | ||||||||||#||||||||||||||||||||||||| | | Sbjct 4 WTRLLPLLALLSLWIPAPTRAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREAEDLQ 62 |
| Pan troglodytes | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 || || ||| ||||| | || |||||||||#||||||||||||||||||||| ||| | | Sbjct 3 LWMRLLPLLVLLALWGPDPASAFVNQHLCG#SHLVEALYLVCGERGFFYTPKTRREAEDLQ 62 |
| Gallus gallus | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 || | |||||| | + | ||||||#||||||||||||||||||+|||||+|| | Sbjct 3 LWIRSLPLLALLVFSGPGTSYAAANQHLCG#SHLVEALYLVCGERGFFYSPKARRDVEQP 61 |
| synthetic construct | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 || || ||||||||| | || |||||||||#||||||||||||||||||||| ||| | | Sbjct 3 LWMRLLPLLALLALWGPDPAAAFVNQHLCG#SHLVEALYLVCGERGFFYTPKTRREAEDLQ 62 |
| Homo sapiens | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 || || ||||||||| | || |||||||||#||||||||||||||||||||| ||| | | Sbjct 3 LWMRLLPLLALLALWGPDPAAAFVNQHLCG#SHLVEALYLVCGERGFFYTPKTRREAEDLQ 62 |
| N/A | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 || || ||||||||| | || |||||||||#||||||||||||||||||||| ||| | | Sbjct 3 LWMRLLPLLALLALWGPDPAAAFVNQHLCG#SHLVEALYLVCGERGFFYTPKTRREAEVGQ 62 |
| Mus musculus | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 || | |||||| || | +||| |||||#|||||||||||||||||||| +||||| || Sbjct 3 LWMRFLPLLALLFLWESHPTQAFVKQHLCG#SHLVEALYLVCGERGFFYTPMSRREVEDPQ 62 |
| Sus scrofa | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 ||||| ||||||||| | ||+|||||||||#||||||||||||||||||||||||| | || Sbjct 3 LWTRLLPLLALLALWAPAPAQAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREAENPQ 62 |
| Canis familiaris | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 || || ||||||||| | | ||||||||||#||||||||||||||||||||||||||| | Sbjct 3 LWMRLLPLLALLALWAPAPTRAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEDLQ 62 |
| Oryctolagus cuniculus | Query 20 PPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 ||+|||||||||#|||||||||||||||||||||+||||| | Sbjct 20 DPAQAFVNQHLCG#SHLVEALYLVCGERGFFYTPKSRREVEELQ 62 |
| Bubalus bubalis | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 ||||||||#|||||||||||||||||||||||||||||| Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 |
| Columba livia | Query 9 PLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 |||||| | + | ||||||#||||||||||||||||||+|||||+|| | Sbjct 2 PLLALLVFSGPGTSYAAANQHLCG#SHLVEALYLVCGERGFFYSPKARRDVEQP 54 |
| Xenopus laevis | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 || + ||+ +| |+ | | ||||||#||||||||||||+||||| || +|++| | Sbjct 3 LWMQCLPLVLVL-LFSTPNTEALANQHLCG#SHLVEALYLVCGDRGFFYYPKIKRDIEQAQ 61 |
| Passer domesticus | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | + | |||||||#|||||||||||||||||| |||||+|| | Sbjct 12 PGSSHAAVNQHLCG#SHLVEALYLVCGERGFFYQPKARRDVEQP 54 |
| Rana pipiens | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 || + + ||+|+ | + | ||+|||#||||||||+|||+|||||+|++||++| | Sbjct 3 LWIQCLHIAVLLSLFTPT-LKTFDNQYLCG#SHLVEALYMVCGDRGFFYSPRSRRDLEQP 60 |
| Aptenodytes forsteri | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | + | ||||||#||||||||||||||||||+|||||+|| | Sbjct 12 PGTSHAAANQHLCG#SHLVEALYLVCGERGFFYSPKARRDVEQP 54 |
| Phaethon aethereus | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | + | ||||||#||||||||||||||||||+|||||++| | Sbjct 12 PGTSHAAANQHLCG#SHLVEALYLVCGERGFFYSPKARRDIEQP 54 |
| Struthio camelus | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | + | ||||||#||||||||||||||||||+|||||++| | Sbjct 12 PGTSHAAANQHLCG#SHLVEALYLVCGERGFFYSPKARRDIEQP 54 |
| Turdus merula | Query 22 ARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 ++| |||||||#|||||||||||||||||| |||||+|| | Sbjct 15 SQAAVNQHLCG#SHLVEALYLVCGERGFFYQPKARRDVEQP 54 |
| Dromaius novaehollandiae | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | ++| ||||||#||||||||||||||||||+|||||+ | | Sbjct 12 PGTSQAAANQHLCG#SHLVEALYLVCGERGFFYSPKARRDAEQP 54 |
| Pica pica | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | + | |+|||||#|||||||||||||||||| |||||++| | Sbjct 12 PGSSHAAVSQHLCG#SHLVEALYLVCGERGFFYQPKARRDIEQP 54 |
| Ciconia ciconia | Query 22 ARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 + | ||||||#||||||||||||||||||+|||||+|| | Sbjct 15 SHAAANQHLCG#SHLVEALYLVCGERGFFYSPKARRDVEQP 54 |
| Sula sula | Query 22 ARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 + | ||||||#||||||||||||||||||+|||||++| | Sbjct 15 SHAAANQHLCG#SHLVEALYLVCGERGFFYSPKARRDIEQP 54 |
| Gallinula chloropus | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | + | |||||#||||||||||||||||||+|||||+|| | Sbjct 12 PGTSHAVATQHLCG#SHLVEALYLVCGERGFFYSPKARRDVEHP 54 |
| Strix aluco | Query 22 ARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 + | ||||||#||||||||||||||||||+|||||++| | Sbjct 15 SHAAANQHLCG#SHLVEALYLVCGERGFFYSPKARRDIEQP 54 |
| Falco tinnunculus | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | + | |||||#||||||||||||||||||+|||||+|| | Sbjct 12 PGTSHAAATQHLCG#SHLVEALYLVCGERGFFYSPKARRDVEQP 54 |
| Anas crecca | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | + | ||||||#||||||||||||||||||+|| ||+|| | Sbjct 12 PGISHAAANQHLCG#SHLVEALYLVCGERGFFYSPKTRRDVEQP 54 |
| Rhea americana | Query 19 PPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | + | ||||||#||||||||||| ||||||+|||||++| | Sbjct 12 PGSSHAAANQHLCG#SHLVEALYLVCRERGFFYSPKARRDIEQP 54 |
| synthetic construct | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPKARREV 58 ||||||||#||||||||||||||||||||| +| + Sbjct 2 FVNQHLCG#SHLVEALYLVCGERGFFYTPKTKRGI 35 |
| Hiodon alosoides | Query 20 PPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVE 59 | |++ +|||||#||||+|||+||||+|||| || +|+|+ Sbjct 19 PGAQSASSQHLCG#SHLVDALYMVCGEKGFFYQPKTKRDVD 58 |
| Chitala chitala | Query 20 PPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPK-ARREVE 59 | | | ||||||#|||||||||||||||||| || +|+ | Sbjct 19 PGANAASNQHLCG#SHLVEALYLVCGERGFFYNPKMDKRDAE 59 |
| Chinchilla brevicaudata | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPKA 54 |||+||||#||||+|||||||+||||||| | Sbjct 1 FVNKHLCG#SHLVDALYLVCGDRGFFYTPMA 30 |
| Dasyprocta punctata | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPK 53 ||||||||#||||||||+ ||++||||||| Sbjct 1 FVNQHLCG#SHLVEALYMACGDKGFFYTPK 29 |
| Gorilla gorilla | Query 31 CG#SHLVEALYLVCGERGFFYTPKARREVEGPQ 62 ||#||||||||||||||||||||| ||| | | Sbjct 1 CG#SHLVEALYLVCGERGFFYTPKTRREAEDLQ 32 |
| Tetraodon nigroviridis | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVE 59 || + +| |+ + | |||||#||||+|||||||+||||| || |+|+ Sbjct 4 LWLQSVSVLLLMVVSSPGSQAMAPPQHLCG#SHLVDALYLVCGDRGFFYNPK--RDVD 58 |
| Osteoglossum bicirrhosum | Query 28 QHLCG#SHLVEALYLVCGERGFFYTPKARREVE 59 | |||#||||+|||+|||+|||||+||+||| | Sbjct 28 QRLCG#SHLVDALYMVCGDRGFFYSPKSRREAE 59 |
| Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | Query 27 NQHLCG#SHLVEALYLVCGERGFFYTPK 53 ||||||#||||||||||||||||||+|| Sbjct 3 NQHLCG#SHLVEALYLVCGERGFFYSPK 29 |
| Danio rerio | Query 7 LRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVE 59 |+ + +| | | +++ +|||||#| ||+||||||| |||||| + ||++| Sbjct 5 LQASVLILLLASLPGSQSSPSQHLCG#SSLVDALYLVCGPRGFFYTNRGRRDLE 57 |
| Gnathonemus petersii | Query 28 QHLCG#SHLVEALYLVCGERGFFYTPKARREVEG 60 |||||#|||||||+|||||||||+ | +|+|+ Sbjct 4 QHLCG#SHLVEALFLVCGERGFFFNPDTKRDVDS 36 |
| thr(B27)->pro,Pro(B28)- >thr | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPKA 54 ||||||||#|||||||||||||||||| | Sbjct 1 FVNQHLCG#SHLVEALYLVCGERGFFYPTKT 30 |
| phe(B25) | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPKA 54 ||||||||#||||||||||||||| ||||| Sbjct 1 FVNQHLCG#SHLVEALYLVCGERG-FYTPKT 29 |
| Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | Query 26 VNQHLCG#SHLVEALYLVCGERGFFYTPK 53 ||+|||#||||||||||||+|||||+|| Sbjct 2 TNQYLCG#SHLVEALYLVCGDRGFFYSPK 29 |
| Oncorhynchus keta | Query 20 PPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVE 59 | | |||||# |||+||||||||+||||||| |+|+ Sbjct 18 PGVDAAAAQHLCG#LHLVDALYLVCGEKGFFYTPK--RDVD 55 |
| Ambloplites rupestris | Query 28 QHLCG#SHLVEALYLVCGERGFFYTPKARREVE 59 |||||#||||+|||||||+||||| || |+|+ Sbjct 4 QHLCG#SHLVDALYLVCGDRGFFYNPK--RDVD 33 |
| Dolichotis patagonum | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPK 53 |||+||||#||||+||| ||+||||| || Sbjct 1 FVNRHLCG#SHLVDALYSACGDRGFFYIPK 29 |
| d-Alab26 | Query 25 FVNQHLCG#SHLVEALYLVCGERGFF 49 ||||||||#||||||||||||||||| Query 25 FVNQHLCG#SHLVEALYLVCGERGFF 49 |
| Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPK 53 | ||||||#|||||||||||||+||+| |+ Sbjct 1 FPNQHLCG#SHLVEALYLVCGEKGFYYIPR 29 |
| Contains: Insulin B chain; Insulin A chain | Query 27 NQHLCG#SHLVEALYLVCGERGFFYTPKARREVEGP 61 | |||#||||+||| |||||||||+|| |+| || Sbjct 3 TQRLCG#SHLVDALYFVCGERGFFYSPKQIRDV-GP 36 |
| Catostomus commersoni | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVE 59 +| + || |||+ | |||||#||||+||||||| |||| || |+|+ Sbjct 3 VWLQAGALLFLLAV-SGVNANGVAPQHLCG#SHLVDALYLVCGPTGFFYNPK--RDVD 56 |
| Hydrochaeris hydrochaeris | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPK 53 |+|+||||#||||+||| ||++|||| || Sbjct 1 FINRHLCG#SHLVDALYSACGDKGFFYVPK 29 |
| Lagidium viscacia | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTP 52 ||+||||#||||||||+|| ++|||||| Sbjct 1 IVNKHLCG#SHLVEALYMVCRDKGFFYTP 28 |
| Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | Query 27 NQHLCG#SHLVEALYLVCGERGFFYTPK 53 ||||#||||||||+|||+||||||| Sbjct 8 GTHLCG#SHLVEALYVVCGDRGFFYTPS 34 |
| Catla catla | Query 3 LWTRLRPLLALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFFYTPKARREVE 59 +| + || |||+ | |||||#||||+||||||| |||| || |+|+ Sbjct 3 VWLQAGALLFLLAV-SSVNANPGAPQHLCG#SHLVDALYLVCGPTGFFYNPK--RDVD 56 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | Query 28 QHLCG#SHLVEALYLVCGERGFFYTPK 53 |||||#||||+|||||||+||||| |+ Sbjct 5 QHLCG#SHLVDALYLVCGDRGFFYNPR 30 |
| Galea musteloides | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPK 53 | |+||||#|+||+|||+|| ++||| || Sbjct 1 FFNRHLCG#SNLVDALYVVCKDKGFFSMPK 29 |
| Cavia porcellus | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPK 53 ||++||||#|+||| || || + |||| || Sbjct 1 FVSRHLCG#SNLVETLYSVCQDDGFFYIPK 29 |
| Microcavia niata | Query 25 FVNQHLCG#SHLVEALYLVCGERGFFYTPK 53 |||+||||#|+||| || || ++||| || Sbjct 1 FVNRHLCG#SNLVETLYEVCRDKGFFSIPK 29 |
| Ctenomys leucodon | Query 25 FVNQHLCG#SHLVEALYLVCGERGFF 49 + +|||||#||||||||+ || ||+ Sbjct 1 YASQHLCG#SHLVEALYMTCGHNGFY 25 |
| Ctenomys robore | Query 25 FVNQHLCG#SHLVEALYLVCGERGFF 49 + +|||||#||||||||+ || ||+ Sbjct 1 YASQHLCG#SHLVEALYMTCGHNGFY 25 |
| Octodontomys gliroides | Query 25 FVNQHLCG#SHLVEALYLVCGERGFF 49 + +|||||#|+||||||+ || ||+ Sbjct 1 YSSQHLCG#SNLVEALYMTCGHNGFY 25 |
| Spalacopus cyanus | Query 25 FVNQHLCG#SHLVEALYLVCGERGFF 49 + +|||||#|+||||||+ || ||+ Sbjct 1 YSSQHLCG#SNLVEALYMTCGRSGFY 25 |
| Tympanoctomys barrerae | Query 25 FVNQHLCG#SHLVEALYLVCGERGFF 49 + +|||||#|+||||||+ || ||+ Sbjct 1 YSSQHLCG#SNLVEALYMTCGHSGFY 25 |
| Octodon degus | Query 25 FVNQHLCG#SHLVEALYLVCGERGFF 49 + +|||||#|+||||||+ || ||+ Sbjct 1 YSSQHLCG#SNLVEALYMTCGRSGFY 25 |
| Octomys mimax | Query 25 FVNQHLCG#SHLVEALYLVCGERGFF 49 + +|||||#|+||||||+ || ||+ Sbjct 1 YSSQHLCG#SNLVEALYMTCGHSGFY 25 |
| Rhabdosargus sarba | Query 11 LALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFF-----YTPKARR 56 | | | | | + |||#+ ||+ | |||||||+ | | ||| Sbjct 2 LLLCVLTLTPTATGASPETLCG#AELVDTLQFVCGERGFYFSKPGYGPNARR 52 |
| Symphysodon aequifasciata | Query 11 LALLALWPPPPARAFVNQHLCG#SHLVEALYLVCGERGFF-----YTPKARR 56 | | | | | + |||#+ ||+ | |||||||+ | | ||| Sbjct 5 LVLCVLTLTPTATGAGPETLCG#AELVDTLQFVCGERGFYFNKPGYGPSARR 55 |
[Site 3] QHLCGSHLVE37-ALYLVCGERG
Glu37 Ala
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gln28 | His29 | Leu30 | Cys31 | Gly32 | Ser33 | His34 | Leu35 | Val36 | Glu37 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ala38 | Leu39 | Tyr40 | Leu41 | Val42 | Cys43 | Gly44 | Glu45 | Arg46 | Gly47 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| RPLLALLALWPPPPARAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALE |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Bos taurus | 122.00 | 1 | proinsulin precursor |
| 2 | Contains: Insulin B chain; Insulin A chain | 94.40 | 18 | INS_CRILO Insulin precursor |
| 3 | Contains: Insulin B chain; Insulin A chain | 92.00 | 7 | INS_PONPY Insulin precursor |
| 4 | Rattus norvegicus | 91.30 | 2 | insulin 2 |
| 5 | Pan troglodytes | 91.30 | 1 | proinsulin precursor |
| 6 | Homo sapiens | 90.90 | 2 | proinsulin precursor |
| 7 | synthetic construct | 90.90 | 2 | Homo sapiens insulin |
| 8 | Mus musculus | 90.10 | 3 | insulin I |
| 9 | Bubalus bubalis | 90.10 | 1 | proinsulin |
| 10 | Oryctolagus cuniculus | 88.20 | 1 | insulin |
| 11 | Sus scrofa | 87.40 | 2 | insulin |
| 12 | N/A | 86.30 | 76 | insulin |
| 13 | Felis catus | 86.30 | 2 | proinsulin precursor |
| 14 | Canis familiaris | 84.30 | 4 | PREDICTED: similar to Insulin precursor |
| 15 | Gallus gallus | 84.00 | 2 | proinsulin precursor |
| 16 | Columba livia | 82.80 | 1 | preproinsulin |
| 17 | Xenopus laevis | 77.80 | 2 | insulin-like growth factor 2 |
| 18 | Passer domesticus | 75.90 | 1 | preproinsulin |
| 19 | Rana pipiens | 75.50 | 1 | AF227187_1 preproinsulin |
| 20 | Aptenodytes forsteri | 75.10 | 1 | preproinsulin |
| 21 | Struthio camelus | 74.70 | 1 | preproinsulin |
| 22 | Phaethon aethereus | 74.70 | 1 | preproinsulin |
| 23 | Turdus merula | 74.70 | 1 | preproinsulin |
| 24 | Dromaius novaehollandiae | 74.30 | 1 | preproinsulin |
| 25 | Ciconia ciconia | 73.60 | 1 | preproinsulin |
| 26 | Pica pica | 73.60 | 1 | preproinsulin |
| 27 | Sula sula | 73.20 | 1 | preproinsulin |
| 28 | Strix aluco | 73.20 | 1 | preproinsulin |
| 29 | Anas crecca | 73.20 | 1 | preproinsulin |
| 30 | Gallinula chloropus | 73.20 | 1 | preproinsulin |
| 31 | Falco tinnunculus | 72.80 | 1 | preproinsulin |
| 32 | Rhea americana | 71.60 | 1 | preproinsulin |
| 33 | synthetic construct | 70.10 | 1 | proinsulin-like protein BKRA |
| 34 | Gorilla gorilla | 67.00 | 1 | insulin |
| 35 | Chitala chitala | 66.60 | 1 | preproinsulin |
| 36 | Hiodon alosoides | 65.50 | 1 | preproinsulin |
| 37 | Chinchilla brevicaudata | 62.00 | 1 | insulin |
| 38 | Dasyprocta punctata | 61.60 | 1 | insulin |
| 39 | Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | 60.80 | 1 | insulin B chain |
| 40 | Osteoglossum bicirrhosum | 60.80 | 1 | preproinsulin |
| 41 | Danio rerio | 60.10 | 3 | preproinsulin b |
| 42 | Gnathonemus petersii | 59.70 | 1 | preproinsulin |
| 43 | thr(B27)->pro,Pro(B28)- >thr | 59.70 | 1 | B Chain B, Solution Structure Of The Monomeric |
| 44 | phe(B25) | 58.90 | 1 | B Chain B, Solution Structure Of The Superactive |
| 45 | Tetraodon nigroviridis | 57.80 | 2 | unnamed protein product |
| 46 | Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | 57.80 | 1 | insulin B-chain |
| 47 | Oncorhynchus keta | 57.40 | 1 | preproinsulin |
| 48 | Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | 56.20 | 1 | insulin B chain |
| 49 | Dolichotis patagonum | 56.20 | 1 | insulin |
| 50 | Contains: Insulin B chain; Insulin A chain | 56.20 | 1 | INS_CALMI Insulin |
| 51 | Ambloplites rupestris | 56.20 | 1 | preproinsulin |
| 52 | d-Alab26 | 55.80 | 1 | B Chain B, |
| 53 | Hydrochaeris hydrochaeris | 55.10 | 1 | insulin |
| 54 | Lagidium viscacia | 54.70 | 1 | insulin |
| 55 | Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | 54.30 | 1 | insulin B-chain |
| 56 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | 53.90 | 1 | insulin B-chain |
| 57 | Catostomus commersoni | 53.10 | 1 | preproinsulin |
| 58 | Catla catla | 52.80 | 1 | AF373021_1 preproinsulin |
| 59 | Galea musteloides | 48.10 | 1 | insulin |
| 60 | Cavia porcellus | 47.40 | 1 | insulin |
| 61 | Microcavia niata | 47.00 | 1 | insulin |
| 62 | Ctenomys robore | 44.70 | 1 | insulin |
| 63 | Ctenomys leucodon | 44.70 | 1 | insulin |
| 64 | Octodontomys gliroides | 42.00 | 1 | insulin |
| 65 | Tympanoctomys barrerae | 41.60 | 1 | insulin |
| 66 | Spalacopus cyanus | 41.60 | 1 | insulin |
| 67 | Octomys mimax | 41.60 | 1 | insulin |
| 68 | Rhabdosargus sarba | 41.20 | 1 | insulin-like growth factor I |
| 69 | Octodon degus | 41.20 | 1 | insulin |
| 70 | Symphysodon aequifasciata | 40.80 | 1 | insulin-like growth factor-1 |
Top-ranked sequences
| organism | matching |
|---|---|
| Bos taurus | Query 8 RPLLALLALWPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 8 RPLLALLALWPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 |
| Contains: Insulin B chain; Insulin A chain | Query 17 WPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 | | ||+||||||||||||||#||||||||||||||||+|| || ||| || Sbjct 17 WEPNPAQAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKSRRGVEDPQVAQLE 67 |
| Contains: Insulin B chain; Insulin A chain | Query 17 WPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 | | ||+||||||||||||||#|||||||||||||||| ||| | ||| +| Sbjct 17 WGPDPAQAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKTRREAEDLQVGQVE 67 |
| Rattus norvegicus | Query 17 WPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 | | ||+||| ||||||||||#||||||||||||||| +||||| ||| || Sbjct 17 WEPRPAQAFVKQHLCGSHLVE#ALYLVCGERGFFYTPMSRREVEDPQVAQLE 67 |
| Pan troglodytes | Query 17 WPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 | | || ||||||||||||||#|||||||||||||||| ||| | ||| +| Sbjct 17 WGPDPASAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKTRREAEDLQVGQVE 67 |
| Homo sapiens | Query 17 WPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 | | || ||||||||||||||#|||||||||||||||| ||| | ||| +| Sbjct 17 WGPDPAAAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKTRREAEDLQVGQVE 67 |
| synthetic construct | Query 17 WPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 | | || ||||||||||||||#|||||||||||||||| ||| | ||| +| Sbjct 17 WGPDPAAAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKTRREAEDLQVGQVE 67 |
| Mus musculus | Query 17 WPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 | | | +||| ||||| ||||#||||||||||||||||+||||| ||| || Sbjct 17 WEPKPTQAFVKQHLCGPHLVE#ALYLVCGERGFFYTPKSRREVEDPQVEQLE 67 |
| Bubalus bubalis | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGAL 66 |||||||||||||#||||||||||||||||||||||||||||| Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGAL 66 |
| Oryctolagus cuniculus | Query 20 PPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 ||+||||||||||||||#||||||||||||||||+||||| ||| | Sbjct 20 DPAQAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKSRREVEELQVGQAE 67 |
| Sus scrofa | Query 23 RAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 +||||||||||||||#|||||||||||||||||||| | || ||+| Sbjct 23 QAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREAENPQAGAVE 67 |
| N/A | Query 17 WPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQV 63 | | || ||||||||||||||#|||||||||||||||| ||| | || Sbjct 17 WGPDPAAAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKTRREAEVGQV 63 |
| Felis catus | Query 17 WPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQ 62 | | | |||||||||||||||#|||||||||||||||||||| | | Sbjct 17 WIPAPTRAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREAEDLQ 62 |
| Canis familiaris | Query 22 ARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 |||||||||||||||#|||||||||||||||||||||| || +| Sbjct 22 TRAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEDLQVRDVE 67 |
| Gallus gallus | Query 9 PLLALLALWPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGA 65 |||||| | + | |||||||||||#|||||||||||||+|||||+|| | | + Sbjct 9 PLLALLVFSGPGTSYAAANQHLCGSHLVE#ALYLVCGERGFFYSPKARRDVEQPLVSS 65 |
| Columba livia | Query 9 PLLALLALWPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 |||||| | + | |||||||||||#|||||||||||||+|||||+|| | Sbjct 2 PLLALLVFSGPGTSYAAANQHLCGSHLVE#ALYLVCGERGFFYSPKARRDVEQP 54 |
| Xenopus laevis | Query 11 LALLALWPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGA 65 | |+ |+ | | |||||||||||#|||||||+||||| || +|++| || Sbjct 10 LVLVLLFSTPNTEALANQHLCGSHLVE#ALYLVCGDRGFFYYPKIKRDIEQAQVNG 64 |
| Passer domesticus | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | + | ||||||||||||#||||||||||||| |||||+|| | Sbjct 12 PGSSHAAVNQHLCGSHLVE#ALYLVCGERGFFYQPKARRDVEQP 54 |
| Rana pipiens | Query 12 ALLALWPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 ||+|+ | + | ||+||||||||#|||+|||+|||||+|++||++| | | |+ Sbjct 12 VLLSLFTPT-LKTFDNQYLCGSHLVE#ALYMVCGDRGFFYSPRSRRDLEQPLVNGLQ 66 |
| Aptenodytes forsteri | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | + | |||||||||||#|||||||||||||+|||||+|| | Sbjct 12 PGTSHAAANQHLCGSHLVE#ALYLVCGERGFFYSPKARRDVEQP 54 |
| Struthio camelus | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | + | |||||||||||#|||||||||||||+|||||++| | Sbjct 12 PGTSHAAANQHLCGSHLVE#ALYLVCGERGFFYSPKARRDIEQP 54 |
| Phaethon aethereus | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | + | |||||||||||#|||||||||||||+|||||++| | Sbjct 12 PGTSHAAANQHLCGSHLVE#ALYLVCGERGFFYSPKARRDIEQP 54 |
| Turdus merula | Query 22 ARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 ++| ||||||||||||#||||||||||||| |||||+|| | Sbjct 15 SQAAVNQHLCGSHLVE#ALYLVCGERGFFYQPKARRDVEQP 54 |
| Dromaius novaehollandiae | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | ++| |||||||||||#|||||||||||||+|||||+ | | Sbjct 12 PGTSQAAANQHLCGSHLVE#ALYLVCGERGFFYSPKARRDAEQP 54 |
| Ciconia ciconia | Query 22 ARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 + | |||||||||||#|||||||||||||+|||||+|| | Sbjct 15 SHAAANQHLCGSHLVE#ALYLVCGERGFFYSPKARRDVEQP 54 |
| Pica pica | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | + | |+||||||||||#||||||||||||| |||||++| | Sbjct 12 PGSSHAAVSQHLCGSHLVE#ALYLVCGERGFFYQPKARRDIEQP 54 |
| Sula sula | Query 22 ARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 + | |||||||||||#|||||||||||||+|||||++| | Sbjct 15 SHAAANQHLCGSHLVE#ALYLVCGERGFFYSPKARRDIEQP 54 |
| Strix aluco | Query 22 ARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 + | |||||||||||#|||||||||||||+|||||++| | Sbjct 15 SHAAANQHLCGSHLVE#ALYLVCGERGFFYSPKARRDIEQP 54 |
| Anas crecca | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | + | |||||||||||#|||||||||||||+|| ||+|| | Sbjct 12 PGISHAAANQHLCGSHLVE#ALYLVCGERGFFYSPKTRRDVEQP 54 |
| Gallinula chloropus | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | + | ||||||||||#|||||||||||||+|||||+|| | Sbjct 12 PGTSHAVATQHLCGSHLVE#ALYLVCGERGFFYSPKARRDVEHP 54 |
| Falco tinnunculus | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | + | ||||||||||#|||||||||||||+|||||+|| | Sbjct 12 PGTSHAAATQHLCGSHLVE#ALYLVCGERGFFYSPKARRDVEQP 54 |
| Rhea americana | Query 19 PPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGP 61 | + | |||||||||||#|||||| ||||||+|||||++| | Sbjct 12 PGSSHAAANQHLCGSHLVE#ALYLVCRERGFFYSPKARRDIEQP 54 |
| synthetic construct | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREV 58 |||||||||||||#|||||||||||||||| +| + Sbjct 2 FVNQHLCGSHLVE#ALYLVCGERGFFYTPKTKRGI 35 |
| Gorilla gorilla | Query 31 CGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGALE 67 |||||||#|||||||||||||||| ||| | ||| +| Sbjct 1 CGSHLVE#ALYLVCGERGFFYTPKTRREAEDLQVGQVE 37 |
| Chitala chitala | Query 20 PPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGAL 66 | | | |||||||||||#||||||||||||| || + | +| | Sbjct 19 PGANAASNQHLCGSHLVE#ALYLVCGERGFFYNPKMDKRDAEPLLGFL 65 |
| Hiodon alosoides | Query 20 PPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVE 59 | |++ +|||||||||+#|||+||||+|||| || +|+|+ Sbjct 19 PGAQSASSQHLCGSHLVD#ALYMVCGEKGFFYQPKTKRDVD 58 |
| Chinchilla brevicaudata | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPKA 54 |||+||||||||+#|||||||+||||||| | Sbjct 1 FVNKHLCGSHLVD#ALYLVCGDRGFFYTPMA 30 |
| Dasyprocta punctata | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPK 53 |||||||||||||#|||+ ||++||||||| Sbjct 1 FVNQHLCGSHLVE#ALYMACGDKGFFYTPK 29 |
| Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | Query 27 NQHLCGSHLVE#ALYLVCGERGFFYTPKA 54 |||||||||||#|||||||||||||+|| Sbjct 3 NQHLCGSHLVE#ALYLVCGERGFFYSPKT 30 |
| Osteoglossum bicirrhosum | Query 28 QHLCGSHLVE#ALYLVCGERGFFYTPKARREVE 59 | |||||||+#|||+|||+|||||+||+||| | Sbjct 28 QRLCGSHLVD#ALYMVCGDRGFFYSPKSRREAE 59 |
| Danio rerio | Query 13 LLALWPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVE 59 +| | | +++ +|||||| ||+#||||||| |||||| + ||++| Sbjct 11 ILLLASLPGSQSSPSQHLCGSSLVD#ALYLVCGPRGFFYTNRGRRDLE 57 |
| Gnathonemus petersii | Query 28 QHLCGSHLVE#ALYLVCGERGFFYTPKARREVEG 60 ||||||||||#||+|||||||||+ | +|+|+ Sbjct 4 QHLCGSHLVE#ALFLVCGERGFFFNPDTKRDVDS 36 |
| thr(B27)->pro,Pro(B28)- >thr | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPKA 54 |||||||||||||#||||||||||||| | Sbjct 1 FVNQHLCGSHLVE#ALYLVCGERGFFYPTKT 30 |
| phe(B25) | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPKA 54 |||||||||||||#|||||||||| ||||| Sbjct 1 FVNQHLCGSHLVE#ALYLVCGERG-FYTPKT 29 |
| Tetraodon nigroviridis | Query 28 QHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGAL 66 |||||||||+#|||||||+||||| || |+|+ | +| | Sbjct 29 QHLCGSHLVD#ALYLVCGDRGFFYNPK--RDVD-PLMGFL 64 |
| Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | Query 26 VNQHLCGSHLVE#ALYLVCGERGFFYTPK 53 ||+||||||||#|||||||+|||||+|| Sbjct 2 TNQYLCGSHLVE#ALYLVCGDRGFFYSPK 29 |
| Oncorhynchus keta | Query 20 PPARAFVNQHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGAL 66 | | ||||| |||+#||||||||+||||||| |+|+ | +| | Sbjct 18 PGVDAAAAQHLCGLHLVD#ALYLVCGEKGFFYTPK--RDVD-PLIGFL 61 |
| Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPK 53 | |||||||||||#||||||||+||+| |+ Sbjct 1 FPNQHLCGSHLVE#ALYLVCGEKGFYYIPR 29 |
| Dolichotis patagonum | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPK 53 |||+||||||||+#||| ||+||||| || Sbjct 1 FVNRHLCGSHLVD#ALYSACGDRGFFYIPK 29 |
| Contains: Insulin B chain; Insulin A chain | Query 27 NQHLCGSHLVE#ALYLVCGERGFFYTPKARREV 58 | |||||||+#||| |||||||||+|| |+| Sbjct 3 TQRLCGSHLVD#ALYFVCGERGFFYSPKQIRDV 34 |
| Ambloplites rupestris | Query 28 QHLCGSHLVE#ALYLVCGERGFFYTPKARREVE 59 |||||||||+#|||||||+||||| || |+|+ Sbjct 4 QHLCGSHLVD#ALYLVCGDRGFFYNPK--RDVD 33 |
| d-Alab26 | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFF 49 |||||||||||||#|||||||||||| Query 25 FVNQHLCGSHLVE#ALYLVCGERGFF 49 |
| Hydrochaeris hydrochaeris | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPK 53 |+|+||||||||+#||| ||++|||| || Sbjct 1 FINRHLCGSHLVD#ALYSACGDKGFFYVPK 29 |
| Lagidium viscacia | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTP 52 ||+|||||||||#|||+|| ++|||||| Sbjct 1 IVNKHLCGSHLVE#ALYMVCRDKGFFYTP 28 |
| Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | Query 27 NQHLCGSHLVE#ALYLVCGERGFFYTPK 53 |||||||||#|||+|||+||||||| Sbjct 8 GTHLCGSHLVE#ALYVVCGDRGFFYTPS 34 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | Query 28 QHLCGSHLVE#ALYLVCGERGFFYTPK 53 |||||||||+#|||||||+||||| |+ Sbjct 5 QHLCGSHLVD#ALYLVCGDRGFFYNPR 30 |
| Catostomus commersoni | Query 28 QHLCGSHLVE#ALYLVCGERGFFYTPKARREVEGPQVGAL 66 |||||||||+#||||||| |||| || |+|+ | +| | Sbjct 27 QHLCGSHLVD#ALYLVCGPTGFFYNPK--RDVD-PLIGFL 62 |
| Catla catla | Query 28 QHLCGSHLVE#ALYLVCGERGFFYTPKARREVE 59 |||||||||+#||||||| |||| || |+|+ Sbjct 27 QHLCGSHLVD#ALYLVCGPTGFFYNPK--RDVD 56 |
| Galea musteloides | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPK 53 | |+|||||+||+#|||+|| ++||| || Sbjct 1 FFNRHLCGSNLVD#ALYVVCKDKGFFSMPK 29 |
| Cavia porcellus | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPK 53 ||++|||||+|||# || || + |||| || Sbjct 1 FVSRHLCGSNLVE#TLYSVCQDDGFFYIPK 29 |
| Microcavia niata | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFFYTPK 53 |||+|||||+|||# || || ++||| || Sbjct 1 FVNRHLCGSNLVE#TLYEVCRDKGFFSIPK 29 |
| Ctenomys robore | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFF 49 + +||||||||||#|||+ || ||+ Sbjct 1 YASQHLCGSHLVE#ALYMTCGHNGFY 25 |
| Ctenomys leucodon | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFF 49 + +||||||||||#|||+ || ||+ Sbjct 1 YASQHLCGSHLVE#ALYMTCGHNGFY 25 |
| Octodontomys gliroides | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFF 49 + +||||||+|||#|||+ || ||+ Sbjct 1 YSSQHLCGSNLVE#ALYMTCGHNGFY 25 |
| Tympanoctomys barrerae | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFF 49 + +||||||+|||#|||+ || ||+ Sbjct 1 YSSQHLCGSNLVE#ALYMTCGHSGFY 25 |
| Spalacopus cyanus | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFF 49 + +||||||+|||#|||+ || ||+ Sbjct 1 YSSQHLCGSNLVE#ALYMTCGRSGFY 25 |
| Octomys mimax | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFF 49 + +||||||+|||#|||+ || ||+ Sbjct 1 YSSQHLCGSNLVE#ALYMTCGHSGFY 25 |
| Rhabdosargus sarba | Query 11 LALLALWPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFF-----YTPKARRE 57 | | | | | + |||+ ||+# | |||||||+ | | ||| Sbjct 2 LLLCVLTLTPTATGASPETLCGAELVD#TLQFVCGERGFYFSKPGYGPNARRS 53 |
| Octodon degus | Query 25 FVNQHLCGSHLVE#ALYLVCGERGFF 49 + +||||||+|||#|||+ || ||+ Sbjct 1 YSSQHLCGSNLVE#ALYMTCGRSGFY 25 |
| Symphysodon aequifasciata | Query 11 LALLALWPPPPARAFVNQHLCGSHLVE#ALYLVCGERGFF-----YTPKARR 56 | | | | | + |||+ ||+# | |||||||+ | | ||| Sbjct 5 LVLCVLTLTPTATGAGPETLCGAELVD#TLQFVCGERGFYFNKPGYGPSARR 55 |
[Site 4] CGSHLVEALY40-LVCGERGFFY
Tyr40 Leu
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Cys31 | Gly32 | Ser33 | His34 | Leu35 | Val36 | Glu37 | Ala38 | Leu39 | Tyr40 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Leu41 | Val42 | Cys43 | Gly44 | Glu45 | Arg46 | Gly47 | Phe48 | Phe49 | Tyr50 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LALLALWPPPPARAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALELAG |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Bos taurus | 122.00 | 1 | proinsulin precursor |
| 2 | Contains: Insulin B chain; Insulin A chain | 98.20 | 18 | INS_CRILO Insulin precursor |
| 3 | Contains: Insulin B chain; Insulin A chain | 95.50 | 7 | INS_PONPY Insulin precursor |
| 4 | Rattus norvegicus | 95.50 | 2 | insulin 2 |
| 5 | Pan troglodytes | 95.10 | 1 | proinsulin precursor |
| 6 | Mus musculus | 94.40 | 3 | insulin I |
| 7 | synthetic construct | 94.40 | 2 | Homo sapiens insulin |
| 8 | Homo sapiens | 94.40 | 2 | proinsulin precursor |
| 9 | N/A | 89.70 | 75 | synthetic preproinsulin |
| 10 | Oryctolagus cuniculus | 89.70 | 1 | insulin |
| 11 | Bubalus bubalis | 89.70 | 1 | proinsulin |
| 12 | Canis familiaris | 89.40 | 4 | PREDICTED: similar to Insulin precursor |
| 13 | Sus scrofa | 87.80 | 2 | preproinsulin |
| 14 | Felis catus | 87.40 | 2 | proinsulin precursor |
| 15 | Gallus gallus | 80.10 | 2 | proinsulin precursor |
| 16 | Columba livia | 78.60 | 1 | preproinsulin |
| 17 | Xenopus laevis | 77.40 | 2 | insulin-like growth factor 2 |
| 18 | Passer domesticus | 75.90 | 1 | preproinsulin |
| 19 | Rana pipiens | 75.50 | 1 | AF227187_1 preproinsulin |
| 20 | Aptenodytes forsteri | 75.10 | 1 | preproinsulin |
| 21 | Phaethon aethereus | 74.70 | 1 | preproinsulin |
| 22 | Turdus merula | 74.70 | 1 | preproinsulin |
| 23 | Struthio camelus | 74.70 | 1 | preproinsulin |
| 24 | Dromaius novaehollandiae | 74.30 | 1 | preproinsulin |
| 25 | Ciconia ciconia | 73.90 | 1 | preproinsulin |
| 26 | Pica pica | 73.60 | 1 | preproinsulin |
| 27 | Sula sula | 73.60 | 1 | preproinsulin |
| 28 | Strix aluco | 73.20 | 1 | preproinsulin |
| 29 | Gallinula chloropus | 73.20 | 1 | preproinsulin |
| 30 | Anas crecca | 73.20 | 1 | preproinsulin |
| 31 | Falco tinnunculus | 72.80 | 1 | preproinsulin |
| 32 | Rhea americana | 72.00 | 1 | preproinsulin |
| 33 | Gorilla gorilla | 70.50 | 1 | insulin |
| 34 | synthetic construct | 69.70 | 1 | proinsulin-like protein BKRA |
| 35 | Chitala chitala | 66.20 | 1 | preproinsulin |
| 36 | Hiodon alosoides | 65.10 | 1 | preproinsulin |
| 37 | Chinchilla brevicaudata | 62.00 | 1 | insulin |
| 38 | Dasyprocta punctata | 61.60 | 1 | insulin |
| 39 | Osteoglossum bicirrhosum | 60.80 | 1 | preproinsulin |
| 40 | Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | 60.50 | 1 | insulin B chain |
| 41 | Danio rerio | 59.70 | 3 | preproinsulin b |
| 42 | Gnathonemus petersii | 59.70 | 1 | preproinsulin |
| 43 | thr(B27)->pro,Pro(B28)- >thr | 59.70 | 1 | B Chain B, Solution Structure Of The Monomeric |
| 44 | phe(B25) | 58.50 | 1 | B Chain B, Solution Structure Of The Superactive |
| 45 | Tetraodon nigroviridis | 57.80 | 2 | unnamed protein product |
| 46 | Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | 57.40 | 1 | insulin B-chain |
| 47 | Oncorhynchus keta | 57.00 | 1 | preproinsulin |
| 48 | Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | 56.20 | 1 | insulin B chain |
| 49 | Dolichotis patagonum | 56.20 | 1 | insulin |
| 50 | Contains: Insulin B chain; Insulin A chain | 56.20 | 1 | INS_CALMI Insulin |
| 51 | Ambloplites rupestris | 56.20 | 1 | preproinsulin |
| 52 | d-Alab26 | 55.80 | 1 | B Chain B, |
| 53 | Hydrochaeris hydrochaeris | 55.10 | 1 | insulin |
| 54 | Lagidium viscacia | 54.70 | 1 | insulin |
| 55 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | 53.90 | 1 | insulin B-chain |
| 56 | Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | 53.90 | 1 | insulin B-chain |
| 57 | Catostomus commersoni | 53.50 | 1 | preproinsulin |
| 58 | Catla catla | 52.80 | 1 | AF373021_1 preproinsulin |
| 59 | Galea musteloides | 48.10 | 1 | insulin |
| 60 | Cavia porcellus | 47.80 | 1 | insulin |
| 61 | Microcavia niata | 47.40 | 1 | insulin |
| 62 | Ctenomys robore | 44.30 | 1 | insulin |
| 63 | Ctenomys leucodon | 44.30 | 1 | insulin |
| 64 | Spalacopus cyanus | 41.60 | 1 | insulin |
| 65 | Octodontomys gliroides | 41.60 | 1 | insulin |
| 66 | Octodon degus | 41.20 | 1 | insulin |
| 67 | Tympanoctomys barrerae | 41.20 | 1 | insulin |
| 68 | Octomys mimax | 41.20 | 1 | insulin |
| 69 | Rhabdosargus sarba | 40.80 | 1 | insulin-like growth factor I |
| 70 | Symphysodon aequifasciata | 40.40 | 1 | insulin-like growth factor-1 |
| 71 | Petromyzon marinus | 38.90 | 1 | Insulin-like growth factor precursor |
Top-ranked sequences
| organism | matching |
|---|---|
| Bos taurus | Query 11 LALLALWPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 11 LALLALWPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 |
| Contains: Insulin B chain; Insulin A chain | Query 17 WPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 | | ||+|||||||||||||||||#|||||||||||||+|| || ||| ||| | Sbjct 17 WEPNPAQAFVNQHLCGSHLVEALY#LVCGERGFFYTPKSRRGVEDPQVAQLELGG 70 |
| Contains: Insulin B chain; Insulin A chain | Query 17 WPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 | | ||+|||||||||||||||||#||||||||||||| ||| | ||| +|| | Sbjct 17 WGPDPAQAFVNQHLCGSHLVEALY#LVCGERGFFYTPKTRREAEDLQVGQVELGG 70 |
| Rattus norvegicus | Query 17 WPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 | | ||+||| |||||||||||||#|||||||||||| +||||| ||| ||| | Sbjct 17 WEPRPAQAFVKQHLCGSHLVEALY#LVCGERGFFYTPMSRREVEDPQVAQLELGG 70 |
| Pan troglodytes | Query 17 WPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 | | || |||||||||||||||||#||||||||||||| ||| | ||| +|| | Sbjct 17 WGPDPASAFVNQHLCGSHLVEALY#LVCGERGFFYTPKTRREAEDLQVGQVELGG 70 |
| Mus musculus | Query 17 WPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 | | | +||| ||||| |||||||#|||||||||||||+||||| ||| ||| | Sbjct 17 WEPKPTQAFVKQHLCGPHLVEALY#LVCGERGFFYTPKSRREVEDPQVEQLELGG 70 |
| synthetic construct | Query 17 WPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 | | || |||||||||||||||||#||||||||||||| ||| | ||| +|| | Sbjct 17 WGPDPAAAFVNQHLCGSHLVEALY#LVCGERGFFYTPKTRREAEDLQVGQVELGG 70 |
| Homo sapiens | Query 17 WPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 | | || |||||||||||||||||#||||||||||||| ||| | ||| +|| | Sbjct 17 WGPDPAAAFVNQHLCGSHLVEALY#LVCGERGFFYTPKTRREAEDLQVGQVELGG 70 |
| N/A | Query 17 WPPPPA----RAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 | | || | ||||||||||||||||#||||||||||||| ||| | ||| +|| | Sbjct 17 WGPDPAAAEFRMFVNQHLCGSHLVEALY#LVCGERGFFYTPKTRREAEDLQVGQVELGG 74 |
| Oryctolagus cuniculus | Query 20 PPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALEL 68 ||+|||||||||||||||||#|||||||||||||+||||| ||| || Sbjct 20 DPAQAFVNQHLCGSHLVEALY#LVCGERGFFYTPKSRREVEELQVGQAEL 68 |
| Bubalus bubalis | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGAL 66 ||||||||||||||||#|||||||||||||||||||||||||| Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGAL 66 |
| Canis familiaris | Query 22 ARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 ||||||||||||||||||#||||||||||||||||||| || +|||| Sbjct 22 TRAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEDLQVRDVELAG 70 |
| Sus scrofa | Query 23 RAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALE 67 +|||||||||||||||||#||||||||||||||||| | || ||+| Sbjct 42 QAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREAENPQAGAVE 86 |
| Felis catus | Query 17 WPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALEL 68 | | | ||||||||||||||||||#||||||||||||||||| | | || Sbjct 17 WIPAPTRAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREAEDLQGKDAEL 68 |
| Gallus gallus | Query 11 LALLALWPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGA 65 |||| | + | ||||||||||||||#||||||||||+|||||+|| | | + Sbjct 11 LALLVFSGPGTSYAAANQHLCGSHLVEALY#LVCGERGFFYSPKARRDVEQPLVSS 65 |
| Columba livia | Query 11 LALLALWPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 |||| | + | ||||||||||||||#||||||||||+|||||+|| | Sbjct 4 LALLVFSGPGTSYAAANQHLCGSHLVEALY#LVCGERGFFYSPKARRDVEQP 54 |
| Xenopus laevis | Query 11 LALLALWPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVG 64 | |+ |+ | | ||||||||||||||#||||+||||| || +|++| || Sbjct 10 LVLVLLFSTPNTEALANQHLCGSHLVEALY#LVCGDRGFFYYPKIKRDIEQAQVN 63 |
| Passer domesticus | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | + | |||||||||||||||#|||||||||| |||||+|| | Sbjct 12 PGSSHAAVNQHLCGSHLVEALY#LVCGERGFFYQPKARRDVEQP 54 |
| Rana pipiens | Query 12 ALLALWPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALE 67 ||+|+ | + | ||+|||||||||||#+|||+|||||+|++||++| | | |+ Sbjct 12 VLLSLFTPT-LKTFDNQYLCGSHLVEALY#MVCGDRGFFYSPRSRRDLEQPLVNGLQ 66 |
| Aptenodytes forsteri | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | + | ||||||||||||||#||||||||||+|||||+|| | Sbjct 12 PGTSHAAANQHLCGSHLVEALY#LVCGERGFFYSPKARRDVEQP 54 |
| Phaethon aethereus | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | + | ||||||||||||||#||||||||||+|||||++| | Sbjct 12 PGTSHAAANQHLCGSHLVEALY#LVCGERGFFYSPKARRDIEQP 54 |
| Turdus merula | Query 22 ARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 ++| |||||||||||||||#|||||||||| |||||+|| | Sbjct 15 SQAAVNQHLCGSHLVEALY#LVCGERGFFYQPKARRDVEQP 54 |
| Struthio camelus | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | + | ||||||||||||||#||||||||||+|||||++| | Sbjct 12 PGTSHAAANQHLCGSHLVEALY#LVCGERGFFYSPKARRDIEQP 54 |
| Dromaius novaehollandiae | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | ++| ||||||||||||||#||||||||||+|||||+ | | Sbjct 12 PGTSQAAANQHLCGSHLVEALY#LVCGERGFFYSPKARRDAEQP 54 |
| Ciconia ciconia | Query 22 ARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 + | ||||||||||||||#||||||||||+|||||+|| | Sbjct 15 SHAAANQHLCGSHLVEALY#LVCGERGFFYSPKARRDVEQP 54 |
| Pica pica | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | + | |+|||||||||||||#|||||||||| |||||++| | Sbjct 12 PGSSHAAVSQHLCGSHLVEALY#LVCGERGFFYQPKARRDIEQP 54 |
| Sula sula | Query 22 ARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 + | ||||||||||||||#||||||||||+|||||++| | Sbjct 15 SHAAANQHLCGSHLVEALY#LVCGERGFFYSPKARRDIEQP 54 |
| Strix aluco | Query 22 ARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 + | ||||||||||||||#||||||||||+|||||++| | Sbjct 15 SHAAANQHLCGSHLVEALY#LVCGERGFFYSPKARRDIEQP 54 |
| Gallinula chloropus | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | + | |||||||||||||#||||||||||+|||||+|| | Sbjct 12 PGTSHAVATQHLCGSHLVEALY#LVCGERGFFYSPKARRDVEHP 54 |
| Anas crecca | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | + | ||||||||||||||#||||||||||+|| ||+|| | Sbjct 12 PGISHAAANQHLCGSHLVEALY#LVCGERGFFYSPKTRRDVEQP 54 |
| Falco tinnunculus | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | + | |||||||||||||#||||||||||+|||||+|| | Sbjct 12 PGTSHAAATQHLCGSHLVEALY#LVCGERGFFYSPKARRDVEQP 54 |
| Rhea americana | Query 19 PPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGP 61 | + | ||||||||||||||#||| ||||||+|||||++| | Sbjct 12 PGSSHAAANQHLCGSHLVEALY#LVCRERGFFYSPKARRDIEQP 54 |
| Gorilla gorilla | Query 31 CGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGALELAG 70 ||||||||||#||||||||||||| ||| | ||| +|| | Sbjct 1 CGSHLVEALY#LVCGERGFFYTPKTRREAEDLQVGQVELGG 40 |
| synthetic construct | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPKARREV 58 ||||||||||||||||#||||||||||||| +| + Sbjct 2 FVNQHLCGSHLVEALY#LVCGERGFFYTPKTKRGI 35 |
| Chitala chitala | Query 20 PPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGAL 66 | | | ||||||||||||||#|||||||||| || + | +| | Sbjct 19 PGANAASNQHLCGSHLVEALY#LVCGERGFFYNPKMDKRDAEPLLGFL 65 |
| Hiodon alosoides | Query 20 PPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVE 59 | |++ +|||||||||+|||#+||||+|||| || +|+|+ Sbjct 19 PGAQSASSQHLCGSHLVDALY#MVCGEKGFFYQPKTKRDVD 58 |
| Chinchilla brevicaudata | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPKA 54 |||+||||||||+|||#||||+||||||| | Sbjct 1 FVNKHLCGSHLVDALY#LVCGDRGFFYTPMA 30 |
| Dasyprocta punctata | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPK 53 ||||||||||||||||#+ ||++||||||| Sbjct 1 FVNQHLCGSHLVEALY#MACGDKGFFYTPK 29 |
| Osteoglossum bicirrhosum | Query 28 QHLCGSHLVEALY#LVCGERGFFYTPKARREVE 59 | |||||||+|||#+|||+|||||+||+||| | Sbjct 28 QRLCGSHLVDALY#MVCGDRGFFYSPKSRREAE 59 |
| Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | Query 27 NQHLCGSHLVEALY#LVCGERGFFYTPKA 54 ||||||||||||||#||||||||||+|| Sbjct 3 NQHLCGSHLVEALY#LVCGERGFFYSPKT 30 |
| Danio rerio | Query 13 LLALWPPPPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVE 59 +| | | +++ +|||||| ||+|||#|||| |||||| + ||++| Sbjct 11 ILLLASLPGSQSSPSQHLCGSSLVDALY#LVCGPRGFFYTNRGRRDLE 57 |
| Gnathonemus petersii | Query 28 QHLCGSHLVEALY#LVCGERGFFYTPKARREVEG 60 ||||||||||||+#|||||||||+ | +|+|+ Sbjct 4 QHLCGSHLVEALF#LVCGERGFFFNPDTKRDVDS 36 |
| thr(B27)->pro,Pro(B28)- >thr | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPKA 54 ||||||||||||||||#|||||||||| | Sbjct 1 FVNQHLCGSHLVEALY#LVCGERGFFYPTKT 30 |
| phe(B25) | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPKA 54 ||||||||||||||||#||||||| ||||| Sbjct 1 FVNQHLCGSHLVEALY#LVCGERG-FYTPKT 29 |
| Tetraodon nigroviridis | Query 28 QHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGAL 66 |||||||||+|||#||||+||||| || |+|+ | +| | Sbjct 29 QHLCGSHLVDALY#LVCGDRGFFYNPK--RDVD-PLMGFL 64 |
| Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | Query 26 VNQHLCGSHLVEALY#LVCGERGFFYTPK 53 ||+|||||||||||#||||+|||||+|| Sbjct 2 TNQYLCGSHLVEALY#LVCGDRGFFYSPK 29 |
| Oncorhynchus keta | Query 20 PPARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGAL 66 | | ||||| |||+|||#|||||+||||||| |+|+ | +| | Sbjct 18 PGVDAAAAQHLCGLHLVDALY#LVCGEKGFFYTPK--RDVD-PLIGFL 61 |
| Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPK 53 | ||||||||||||||#|||||+||+| |+ Sbjct 1 FPNQHLCGSHLVEALY#LVCGEKGFYYIPR 29 |
| Dolichotis patagonum | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPK 53 |||+||||||||+|||# ||+||||| || Sbjct 1 FVNRHLCGSHLVDALY#SACGDRGFFYIPK 29 |
| Contains: Insulin B chain; Insulin A chain | Query 27 NQHLCGSHLVEALY#LVCGERGFFYTPKARREV 58 | |||||||+|||# |||||||||+|| |+| Sbjct 3 TQRLCGSHLVDALY#FVCGERGFFYSPKQIRDV 34 |
| Ambloplites rupestris | Query 28 QHLCGSHLVEALY#LVCGERGFFYTPKARREVE 59 |||||||||+|||#||||+||||| || |+|+ Sbjct 4 QHLCGSHLVDALY#LVCGDRGFFYNPK--RDVD 33 |
| d-Alab26 | Query 25 FVNQHLCGSHLVEALY#LVCGERGFF 49 ||||||||||||||||#||||||||| Query 25 FVNQHLCGSHLVEALY#LVCGERGFF 49 |
| Hydrochaeris hydrochaeris | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPK 53 |+|+||||||||+|||# ||++|||| || Sbjct 1 FINRHLCGSHLVDALY#SACGDKGFFYVPK 29 |
| Lagidium viscacia | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTP 52 ||+||||||||||||#+|| ++|||||| Sbjct 1 IVNKHLCGSHLVEALY#MVCRDKGFFYTP 28 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | Query 28 QHLCGSHLVEALY#LVCGERGFFYTPK 53 |||||||||+|||#||||+||||| |+ Sbjct 5 QHLCGSHLVDALY#LVCGDRGFFYNPR 30 |
| Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | Query 27 NQHLCGSHLVEALY#LVCGERGFFYTPK 53 ||||||||||||#+|||+||||||| Sbjct 8 GTHLCGSHLVEALY#VVCGDRGFFYTPS 34 |
| Catostomus commersoni | Query 28 QHLCGSHLVEALY#LVCGERGFFYTPKARREVEGPQVGAL 66 |||||||||+|||#|||| |||| || |+|+ | +| | Sbjct 27 QHLCGSHLVDALY#LVCGPTGFFYNPK--RDVD-PLIGFL 62 |
| Catla catla | Query 28 QHLCGSHLVEALY#LVCGERGFFYTPKARREVE 59 |||||||||+|||#|||| |||| || |+|+ Sbjct 27 QHLCGSHLVDALY#LVCGPTGFFYNPK--RDVD 56 |
| Galea musteloides | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPK 53 | |+|||||+||+|||#+|| ++||| || Sbjct 1 FFNRHLCGSNLVDALY#VVCKDKGFFSMPK 29 |
| Cavia porcellus | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPK 53 ||++|||||+||| ||# || + |||| || Sbjct 1 FVSRHLCGSNLVETLY#SVCQDDGFFYIPK 29 |
| Microcavia niata | Query 25 FVNQHLCGSHLVEALY#LVCGERGFFYTPK 53 |||+|||||+||| ||# || ++||| || Sbjct 1 FVNRHLCGSNLVETLY#EVCRDKGFFSIPK 29 |
| Ctenomys robore | Query 25 FVNQHLCGSHLVEALY#LVCGERGFF 49 + +|||||||||||||#+ || ||+ Sbjct 1 YASQHLCGSHLVEALY#MTCGHNGFY 25 |
| Ctenomys leucodon | Query 25 FVNQHLCGSHLVEALY#LVCGERGFF 49 + +|||||||||||||#+ || ||+ Sbjct 1 YASQHLCGSHLVEALY#MTCGHNGFY 25 |
| Spalacopus cyanus | Query 25 FVNQHLCGSHLVEALY#LVCGERGFF 49 + +||||||+||||||#+ || ||+ Sbjct 1 YSSQHLCGSNLVEALY#MTCGRSGFY 25 |
| Octodontomys gliroides | Query 25 FVNQHLCGSHLVEALY#LVCGERGFF 49 + +||||||+||||||#+ || ||+ Sbjct 1 YSSQHLCGSNLVEALY#MTCGHNGFY 25 |
| Octodon degus | Query 25 FVNQHLCGSHLVEALY#LVCGERGFF 49 + +||||||+||||||#+ || ||+ Sbjct 1 YSSQHLCGSNLVEALY#MTCGRSGFY 25 |
| Tympanoctomys barrerae | Query 25 FVNQHLCGSHLVEALY#LVCGERGFF 49 + +||||||+||||||#+ || ||+ Sbjct 1 YSSQHLCGSNLVEALY#MTCGHSGFY 25 |
| Octomys mimax | Query 25 FVNQHLCGSHLVEALY#LVCGERGFF 49 + +||||||+||||||#+ || ||+ Sbjct 1 YSSQHLCGSNLVEALY#MTCGHSGFY 25 |
| Rhabdosargus sarba | Query 11 LALLALWPPPPARAFVNQHLCGSHLVEALY#LVCGERGFF-----YTPKARR 56 | | | | | + |||+ ||+ | # |||||||+ | | ||| Sbjct 2 LLLCVLTLTPTATGASPETLCGAELVDTLQ#FVCGERGFYFSKPGYGPNARR 52 |
| Symphysodon aequifasciata | Query 11 LALLALWPPPPARAFVNQHLCGSHLVEALY#LVCGERGFF-----YTPKARR 56 | | | | | + |||+ ||+ | # |||||||+ | | ||| Sbjct 5 LVLCVLTLTPTATGAGPETLCGAELVDTLQ#FVCGERGFYFNKPGYGPSARR 55 |
| Petromyzon marinus | Query 21 PARAFVNQHLCGSHLVEALY#LVCGERGFFYTPKARREVEG-PQVGALE 67 | || ++ |||| ||+|| # |||+|||++ | |+ | +| Sbjct 51 PVRA--SETLCGSELVDALQ#FVCGDRGFYFVRHPSSRSHGRPKKGIVE 96 |
[Site 5] LVCGERGFFY50-TPKARREVEG
Tyr50 Thr
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Leu41 | Val42 | Cys43 | Gly44 | Glu45 | Arg46 | Gly47 | Phe48 | Phe49 | Tyr50 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr51 | Pro52 | Lys53 | Ala54 | Arg55 | Arg56 | Glu57 | Val58 | Glu59 | Gly60 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| PARAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALELAGGPGAGGLEGP |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Bos taurus | 120.00 | 1 | proinsulin precursor |
| 2 | Contains: Insulin B chain; Insulin A chain | 119.00 | 18 | INS_SHEEP Insulin precursor |
| 3 | Bubalus bubalis | 113.00 | 1 | proinsulin |
| 4 | Mus musculus | 101.00 | 3 | insulin II |
| 5 | Rattus norvegicus | 101.00 | 2 | insulin 2 |
| 6 | Contains: Insulin B chain; Insulin A chain | 100.00 | 7 | INS_PONPY Insulin precursor |
| 7 | Canis familiaris | 100.00 | 1 | PREDICTED: similar to Insulin precursor |
| 8 | Pan troglodytes | 100.00 | 1 | proinsulin precursor |
| 9 | Homo sapiens | 99.80 | 2 | proinsulin precursor |
| 10 | synthetic construct | 99.80 | 2 | Homo sapiens insulin |
| 11 | N/A | 98.20 | 75 | 1006230A insulin,pro- |
| 12 | Felis catus | 93.20 | 2 | proinsulin precursor |
| 13 | Oryctolagus cuniculus | 89.40 | 1 | insulin |
| 14 | Sus scrofa | 87.40 | 2 | preproinsulin |
| 15 | Gorilla gorilla | 80.90 | 1 | insulin |
| 16 | Turdus merula | 74.70 | 1 | preproinsulin |
| 17 | Gallus gallus | 74.30 | 2 | proinsulin precursor |
| 18 | Passer domesticus | 74.30 | 1 | preproinsulin |
| 19 | Aptenodytes forsteri | 73.60 | 1 | preproinsulin |
| 20 | Ciconia ciconia | 73.60 | 1 | preproinsulin |
| 21 | Phaethon aethereus | 73.20 | 1 | preproinsulin |
| 22 | Sula sula | 73.20 | 1 | preproinsulin |
| 23 | Struthio camelus | 73.20 | 1 | preproinsulin |
| 24 | Strix aluco | 73.20 | 1 | preproinsulin |
| 25 | Xenopus laevis | 72.80 | 3 | insulin-like growth factor 2 |
| 26 | Columba livia | 72.80 | 1 | preproinsulin |
| 27 | Dromaius novaehollandiae | 72.80 | 1 | preproinsulin |
| 28 | Rana pipiens | 72.40 | 1 | AF227187_1 preproinsulin |
| 29 | Pica pica | 72.00 | 1 | preproinsulin |
| 30 | Anas crecca | 72.00 | 1 | preproinsulin |
| 31 | Gallinula chloropus | 71.60 | 1 | preproinsulin |
| 32 | Falco tinnunculus | 71.20 | 1 | preproinsulin |
| 33 | Rhea americana | 70.90 | 1 | preproinsulin |
| 34 | synthetic construct | 69.30 | 1 | proinsulin-like protein BKRA |
| 35 | Chitala chitala | 65.50 | 1 | preproinsulin |
| 36 | Hiodon alosoides | 63.50 | 1 | preproinsulin |
| 37 | Chinchilla brevicaudata | 62.00 | 1 | insulin |
| 38 | Osteoglossum bicirrhosum | 61.20 | 1 | preproinsulin |
| 39 | Dasyprocta punctata | 60.80 | 1 | insulin |
| 40 | Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | 60.50 | 1 | insulin B chain |
| 41 | Gnathonemus petersii | 60.50 | 1 | preproinsulin |
| 42 | thr(B27)->pro,Pro(B28)- >thr | 59.70 | 1 | B Chain B, Solution Structure Of The Monomeric |
| 43 | phe(B25) | 58.50 | 1 | B Chain B, Solution Structure Of The Superactive |
| 44 | Danio rerio | 57.80 | 3 | preproinsulin b |
| 45 | Tetraodon nigroviridis | 57.80 | 2 | unnamed protein product |
| 46 | Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | 57.40 | 1 | insulin B-chain |
| 47 | Oncorhynchus keta | 57.00 | 1 | preproinsulin |
| 48 | Ambloplites rupestris | 56.60 | 1 | preproinsulin |
| 49 | Contains: Insulin B chain; Insulin A chain | 56.20 | 1 | INS_CALMI Insulin |
| 50 | Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | 56.20 | 1 | insulin B chain |
| 51 | Catostomus commersoni | 55.80 | 1 | preproinsulin |
| 52 | Dolichotis patagonum | 55.80 | 1 | insulin |
| 53 | d-Alab26 | 55.50 | 1 | B Chain B, |
| 54 | Lagidium viscacia | 55.10 | 1 | insulin |
| 55 | Hydrochaeris hydrochaeris | 54.30 | 1 | insulin |
| 56 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | 53.90 | 1 | insulin B-chain |
| 57 | Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | 53.50 | 1 | insulin B-chain |
| 58 | Catla catla | 53.10 | 1 | AF373021_1 preproinsulin |
| 59 | Galea musteloides | 48.10 | 1 | insulin |
| 60 | Cavia porcellus | 47.80 | 1 | insulin |
| 61 | Microcavia niata | 47.00 | 1 | insulin |
| 62 | Ctenomys robore | 43.90 | 1 | insulin |
| 63 | Ctenomys leucodon | 43.90 | 1 | insulin |
| 64 | Tympanoctomys barrerae | 40.80 | 1 | insulin |
| 65 | Octodontomys gliroides | 40.80 | 1 | insulin |
| 66 | Spalacopus cyanus | 40.80 | 1 | insulin |
| 67 | Octomys mimax | 40.80 | 1 | insulin |
| 68 | Octodon degus | 40.40 | 1 | insulin |
| 69 | Petromyzon marinus | 38.10 | 1 | Insulin-like growth factor precursor |
| 70 | Rhabdosargus sarba | 37.40 | 1 | insulin-like growth factor I |
Top-ranked sequences
| organism | matching |
|---|---|
| Bos taurus | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLEGP 80 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLEGP 80 |
| Contains: Insulin B chain; Insulin A chain | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLEGP 80 || |||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 21 PAHAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLEGP 80 |
| Bubalus bubalis | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLEGP 80 ||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLEGP 80 |
| Mus musculus | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 | +||| |||||||||||||||||||||||#|| +||||| ||| ||| |||||| |+ Sbjct 21 PTQAFVKQHLCGSHLVEALYLVCGERGFFY#TPMSRREVEDPQVAQLELGGGPGAGDLQ 78 |
| Rattus norvegicus | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 ||+||| |||||||||||||||||||||||#|| +||||| ||| ||| |||||| |+ Sbjct 21 PAQAFVKQHLCGSHLVEALYLVCGERGFFY#TPMSRREVEDPQVAQLELGGGPGAGDLQ 78 |
| Contains: Insulin B chain; Insulin A chain | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 ||+|||||||||||||||||||||||||||#||| ||| | ||| +|| |||||| |+ Sbjct 21 PAQAFVNQHLCGSHLVEALYLVCGERGFFY#TPKTRREAEDLQVGQVELGGGPGAGSLQ 78 |
| Canis familiaris | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 ||||||||||||||||||||||||||||#||||||||| || +|||| || |||+ Sbjct 22 TRAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEDLQVRDVELAGAPGEGGLQ 78 |
| Pan troglodytes | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 || |||||||||||||||||||||||||||#||| ||| | ||| +|| |||||| |+ Sbjct 21 PASAFVNQHLCGSHLVEALYLVCGERGFFY#TPKTRREAEDLQVGQVELGGGPGAGSLQ 78 |
| Homo sapiens | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 || |||||||||||||||||||||||||||#||| ||| | ||| +|| |||||| |+ Sbjct 21 PAAAFVNQHLCGSHLVEALYLVCGERGFFY#TPKTRREAEDLQVGQVELGGGPGAGSLQ 78 |
| synthetic construct | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 || |||||||||||||||||||||||||||#||| ||| | ||| +|| |||||| |+ Sbjct 21 PAAAFVNQHLCGSHLVEALYLVCGERGFFY#TPKTRREAEDLQVGQVELGGGPGAGSLQ 78 |
| N/A | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 ||||||||||||||||||||||||||#||| ||| | |||| +|| |||||| |+ Sbjct 1 FVNQHLCGSHLVEALYLVCGERGFFY#TPKTRREAEDPQVGQVELGGGPGAGSLQ 54 |
| Felis catus | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 | ||||||||||||||||||||||||||||#||||||| | | || ||||||+ Sbjct 21 PTRAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREAEDLQGKDAELGEAPGAGGLQ 78 |
| Oryctolagus cuniculus | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALEL 68 ||+|||||||||||||||||||||||||||#|||+||||| ||| || Sbjct 21 PAQAFVNQHLCGSHLVEALYLVCGERGFFY#TPKSRREVEELQVGQAEL 68 |
| Sus scrofa | Query 23 RAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALE 67 +|||||||||||||||||||||||||||#||||||| | || ||+| Sbjct 42 QAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREAENPQAGAVE 86 |
| Gorilla gorilla | Query 31 CGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLE 78 ||||||||||||||||||||#||| ||| | ||| +|| |||||| |+ Sbjct 1 CGSHLVEALYLVCGERGFFY#TPKTRREAEDLQVGQVELGGGPGAGSLQ 48 |
| Turdus merula | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 ++| |||||||||||||||||||||||||# |||||+|| | Sbjct 15 SQAAVNQHLCGSHLVEALYLVCGERGFFY#QPKARRDVEQP 54 |
| Gallus gallus | Query 24 AFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGA 65 | ||||||||||||||||||||||||#+|||||+|| | | + Sbjct 24 AAANQHLCGSHLVEALYLVCGERGFFY#SPKARRDVEQPLVSS 65 |
| Passer domesticus | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | |||||||||||||||||||||||||# |||||+|| | Sbjct 15 SHAAVNQHLCGSHLVEALYLVCGERGFFY#QPKARRDVEQP 54 |
| Aptenodytes forsteri | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | ||||||||||||||||||||||||#+|||||+|| | Sbjct 15 SHAAANQHLCGSHLVEALYLVCGERGFFY#SPKARRDVEQP 54 |
| Ciconia ciconia | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | ||||||||||||||||||||||||#+|||||+|| | Sbjct 15 SHAAANQHLCGSHLVEALYLVCGERGFFY#SPKARRDVEQP 54 |
| Phaethon aethereus | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | ||||||||||||||||||||||||#+|||||++| | Sbjct 15 SHAAANQHLCGSHLVEALYLVCGERGFFY#SPKARRDIEQP 54 |
| Sula sula | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | ||||||||||||||||||||||||#+|||||++| | Sbjct 15 SHAAANQHLCGSHLVEALYLVCGERGFFY#SPKARRDIEQP 54 |
| Struthio camelus | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | ||||||||||||||||||||||||#+|||||++| | Sbjct 15 SHAAANQHLCGSHLVEALYLVCGERGFFY#SPKARRDIEQP 54 |
| Strix aluco | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | ||||||||||||||||||||||||#+|||||++| | Sbjct 15 SHAAANQHLCGSHLVEALYLVCGERGFFY#SPKARRDIEQP 54 |
| Xenopus laevis | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLEG 79 | ||||||||||||||||||+|||||# || +|++| || || |+| Sbjct 21 TEALANQHLCGSHLVEALYLVCGDRGFFY#YPKIKRDIEQAQV------NGPQDNELDG 72 |
| Columba livia | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | ||||||||||||||||||||||||#+|||||+|| | Sbjct 15 SYAAANQHLCGSHLVEALYLVCGERGFFY#SPKARRDVEQP 54 |
| Dromaius novaehollandiae | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 ++| ||||||||||||||||||||||||#+|||||+ | | Sbjct 15 SQAAANQHLCGSHLVEALYLVCGERGFFY#SPKARRDAEQP 54 |
| Rana pipiens | Query 23 RAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALE 67 + | ||+|||||||||||+|||+|||||#+|++||++| | | |+ Sbjct 22 KTFDNQYLCGSHLVEALYMVCGDRGFFY#SPRSRRDLEQPLVNGLQ 66 |
| Pica pica | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | |+|||||||||||||||||||||||# |||||++| | Sbjct 15 SHAAVSQHLCGSHLVEALYLVCGERGFFY#QPKARRDIEQP 54 |
| Anas crecca | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | ||||||||||||||||||||||||#+|| ||+|| | Sbjct 15 SHAAANQHLCGSHLVEALYLVCGERGFFY#SPKTRRDVEQP 54 |
| Gallinula chloropus | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | |||||||||||||||||||||||#+|||||+|| | Sbjct 15 SHAVATQHLCGSHLVEALYLVCGERGFFY#SPKARRDVEHP 54 |
| Falco tinnunculus | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | |||||||||||||||||||||||#+|||||+|| | Sbjct 15 SHAAATQHLCGSHLVEALYLVCGERGFFY#SPKARRDVEQP 54 |
| Rhea americana | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGP 61 + | ||||||||||||||||| ||||||#+|||||++| | Sbjct 15 SHAAANQHLCGSHLVEALYLVCRERGFFY#SPKARRDIEQP 54 |
| synthetic construct | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPKARR 56 ||||||||||||||||||||||||||#||| +| Sbjct 2 FVNQHLCGSHLVEALYLVCGERGFFY#TPKTKR 33 |
| Chitala chitala | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGG 71 | | ||||||||||||||||||||||||# || + | +| | | Sbjct 21 ANAASNQHLCGSHLVEALYLVCGERGFFY#NPKMDKRDAEPLLGFLSPKSG 70 |
| Hiodon alosoides | Query 22 ARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGAL 66 |++ +|||||||||+|||+||||+||||# || +|+|+ | +| | Sbjct 21 AQSASSQHLCGSHLVDALYMVCGEKGFFY#QPKTKRDVD-PLLGFL 64 |
| Chinchilla brevicaudata | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPKA 54 |||+||||||||+|||||||+|||||#|| | Sbjct 1 FVNKHLCGSHLVDALYLVCGDRGFFY#TPMA 30 |
| Osteoglossum bicirrhosum | Query 28 QHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGG 71 | |||||||+|||+|||+|||||#+||+||| | | +| | | Sbjct 28 QRLCGSHLVDALYMVCGDRGFFY#SPKSRREAE-PLLGFLSPKSG 70 |
| Dasyprocta punctata | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPK 53 ||||||||||||||||+ ||++||||#||| Sbjct 1 FVNQHLCGSHLVEALYMACGDKGFFY#TPK 29 |
| Cairina moschata=Muscovy ducks, pancreas, Peptide, 30 aa | Query 27 NQHLCGSHLVEALYLVCGERGFFY#TPKA 54 ||||||||||||||||||||||||#+|| Sbjct 3 NQHLCGSHLVEALYLVCGERGFFY#SPKT 30 |
| Gnathonemus petersii | Query 28 QHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGP 72 ||||||||||||+|||||||||+# | +|+|+ +| | || Sbjct 4 QHLCGSHLVEALFLVCGERGFFF#NPDTKRDVDS-LLGFLSPKSGP 47 |
| thr(B27)->pro,Pro(B28)- >thr | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPKA 54 ||||||||||||||||||||||||||# | Sbjct 1 FVNQHLCGSHLVEALYLVCGERGFFY#PTKT 30 |
| phe(B25) | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPKA 54 ||||||||||||||||||||||| ||#||| Sbjct 1 FVNQHLCGSHLVEALYLVCGERG-FY#TPKT 29 |
| Danio rerio | Query 27 NQHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGG 76 +|||||| ||+||||||| |||||#| + ||++| ||| | Sbjct 25 SQHLCGSSLVDALYLVCGPRGFFY#TNRGRRDLETLLALLSNLAGYEAADA 74 |
| Tetraodon nigroviridis | Query 28 QHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGAL 66 |||||||||+|||||||+|||||# || |+|+ | +| | Sbjct 29 QHLCGSHLVDALYLVCGDRGFFY#NPK--RDVD-PLMGFL 64 |
| Amphiuma tridactylum=three-toed amphiuma, pancreatic extract, Peptide, 29 aa | Query 26 VNQHLCGSHLVEALYLVCGERGFFY#TPK 53 ||+|||||||||||||||+|||||#+|| Sbjct 2 TNQYLCGSHLVEALYLVCGDRGFFY#SPK 29 |
| Oncorhynchus keta | Query 28 QHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGAL 66 ||||| |||+||||||||+||||#||| |+|+ | +| | Sbjct 26 QHLCGLHLVDALYLVCGEKGFFY#TPK--RDVD-PLIGFL 61 |
| Ambloplites rupestris | Query 28 QHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGPGAGGLEGP 80 |||||||||+|||||||+|||||# || |+|+ | +| | | | | | Sbjct 4 QHLCGSHLVDALYLVCGDRGFFY#NPK--RDVD-PLMGFLP----PKADGAAAP 49 |
| Contains: Insulin B chain; Insulin A chain | Query 27 NQHLCGSHLVEALYLVCGERGFFY#TPKARREV 58 | |||||||+||| |||||||||#+|| |+| Sbjct 3 TQRLCGSHLVDALYFVCGERGFFY#SPKQIRDV 34 |
| Ornithorhynchus anatinus=platypuses, pancreas, Peptide, 30 aa | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPK 53 | |||||||||||||||||||+||+|# |+ Sbjct 1 FPNQHLCGSHLVEALYLVCGEKGFYY#IPR 29 |
| Catostomus commersoni | Query 28 QHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGALELAGGP 72 |||||||||+||||||| ||||# || |+|+ | +| | || Sbjct 27 QHLCGSHLVDALYLVCGPTGFFY#NPK--RDVD-PLIGFLPPKSGP 68 |
| Dolichotis patagonum | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPK 53 |||+||||||||+||| ||+|||||# || Sbjct 1 FVNRHLCGSHLVDALYSACGDRGFFY#IPK 29 |
| d-Alab26 | Query 25 FVNQHLCGSHLVEALYLVCGERGFF 49 ||||||||||||||||||||||||| Query 25 FVNQHLCGSHLVEALYLVCGERGFF 49 |
| Lagidium viscacia | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TP 52 ||+||||||||||||+|| ++||||#|| Sbjct 1 IVNKHLCGSHLVEALYMVCRDKGFFY#TP 28 |
| Hydrochaeris hydrochaeris | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPK 53 |+|+||||||||+||| ||++||||# || Sbjct 1 FINRHLCGSHLVDALYSACGDKGFFY#VPK 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 30 aa | Query 28 QHLCGSHLVEALYLVCGERGFFY#TPK 53 |||||||||+|||||||+|||||# |+ Sbjct 5 QHLCGSHLVDALYLVCGDRGFFY#NPR 30 |
| Lampetra fluviatilis=river lamprey, pancreatic tissues, Peptide, 36 aa | Query 28 QHLCGSHLVEALYLVCGERGFFY#TPK 53 ||||||||||||+|||+|||||#|| Sbjct 9 THLCGSHLVEALYVVCGDRGFFY#TPS 34 |
| Catla catla | Query 28 QHLCGSHLVEALYLVCGERGFFY#TPKARREVEGPQVGAL 66 |||||||||+||||||| ||||# || |+|+ | +| | Sbjct 27 QHLCGSHLVDALYLVCGPTGFFY#NPK--RDVD-PLMGFL 62 |
| Galea musteloides | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPK 53 | |+|||||+||+|||+|| ++||| # || Sbjct 1 FFNRHLCGSNLVDALYVVCKDKGFFS#MPK 29 |
| Cavia porcellus | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPK 53 ||++|||||+||| || || + ||||# || Sbjct 1 FVSRHLCGSNLVETLYSVCQDDGFFY#IPK 29 |
| Microcavia niata | Query 25 FVNQHLCGSHLVEALYLVCGERGFFY#TPK 53 |||+|||||+||| || || ++||| # || Sbjct 1 FVNRHLCGSNLVETLYEVCRDKGFFS#IPK 29 |
| Ctenomys robore | Query 25 FVNQHLCGSHLVEALYLVCGERGFF 49 + +|||||||||||||+ || ||+ Sbjct 1 YASQHLCGSHLVEALYMTCGHNGFY 25 |
| Ctenomys leucodon | Query 25 FVNQHLCGSHLVEALYLVCGERGFF 49 + +|||||||||||||+ || ||+ Sbjct 1 YASQHLCGSHLVEALYMTCGHNGFY 25 |
| Tympanoctomys barrerae | Query 25 FVNQHLCGSHLVEALYLVCGERGFF 49 + +||||||+||||||+ || ||+ Sbjct 1 YSSQHLCGSNLVEALYMTCGHSGFY 25 |
| Octodontomys gliroides | Query 25 FVNQHLCGSHLVEALYLVCGERGFF 49 + +||||||+||||||+ || ||+ Sbjct 1 YSSQHLCGSNLVEALYMTCGHNGFY 25 |
| Spalacopus cyanus | Query 25 FVNQHLCGSHLVEALYLVCGERGFF 49 + +||||||+||||||+ || ||+ Sbjct 1 YSSQHLCGSNLVEALYMTCGRSGFY 25 |
| Octomys mimax | Query 25 FVNQHLCGSHLVEALYLVCGERGFF 49 + +||||||+||||||+ || ||+ Sbjct 1 YSSQHLCGSNLVEALYMTCGHSGFY 25 |
| Octodon degus | Query 25 FVNQHLCGSHLVEALYLVCGERGFF 49 + +||||||+||||||+ || ||+ Sbjct 1 YSSQHLCGSNLVEALYMTCGRSGFY 25 |
| Petromyzon marinus | Query 21 PARAFVNQHLCGSHLVEALYLVCGERGFFY#TPKARREVEG-PQVGALE 67 | || ++ |||| ||+|| |||+|||++# | |+ | +| Sbjct 51 PVRA--SETLCGSELVDALQFVCGDRGFYF#VRHPSSRSHGRPKKGIVE 96 |
| Rhabdosargus sarba | Query 28 QHLCGSHLVEALYLVCGERGFFY#T-----PKARR 56 + |||+ ||+ | |||||||++#+ | ||| Sbjct 19 ETLCGAELVDTLQFVCGERGFYF#SKPGYGPNARR 52 |
* References
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