SB0062 : Integrin [beta]7
[ CaMP Format ]
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | integrin beta-7 precursor [Homo sapiens]; integrin beta-7 precursor; integrin beta-7; integrin beta 7 subunit; gut homing receptor beta subunit; Integrin beta-7; Gut homing receptor beta subunit |
| Gene Names | ITGB7; integrin, beta 7 |
| Gene Locus | 12q13.13; chromosome 12 |
| GO Function | Not available |
* Information From OMIM
Function: Whereas naive T cells migrate only to secondary lymphoid organs, activation by antigen confers to T cells the ability to home to nonlymphoid sites. Activated effector/memory T cells migrate preferentially to tissues that are connected to the secondary lymphoid organs where antigen was first encountered. Thus, oral antigens induce effector/memory cells that express essential receptors for intestinal homing, namely the integrin alpha-4-beta-7 (see OMIM:192975) and CCR9 (OMIM:604738), the receptor for the gut-associated chemokine TECK/CCL25 (OMIM:602565). Mora et al. (2003) showed that this imprinting of gut tropism is mediated by dendritic cells from Peyer patches. Stimulation of CD8 (see OMIM:186910)-expressing T cells by dendritic cells from Peyer patches, peripheral lymph nodes, and spleen induced equivalent activation markers and effector activity in T cells, but only Peyer patch dendritic cells induced high levels of alpha-4-beta-7, responsiveness to TECK, and the ability to home to the small intestine. Mora et al. (2003) concluded that their findings established that Peyer patch dendritic cells imprint gut-homing specificity on T cells, and thus license effector/memory cells to access anatomic sites most likely to contain their cognate antigen.
* Structure Information
1. Primary Information
Length: 798 aa
Average Mass: 86.902 kDa
Monoisotopic Mass: 86.847 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| EGF-like domain 1. | 425 | 429 | 11.0 | 0.1 |
| EGF-like domain 2. | 474 | 488 | 18.0 | 3.2 |
| EGF-like domain 3. | 527 | 559 | 1.0 | 17.9 |
| EGF-like domain 4. | 566 | 596 | 1.0 | 15.8 |
| EGF-like domain 5. | 605 | 635 | 1.0 | 14.8 |
| EGF-like domain 6. | 641 | 655 | 1.0 | 3.6 |
| Integrin beta cytoplasmic domain 1. | 747 | 791 | 1.0 | 0.6 |
| --- cleavage 760 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
| --- cleavage 765 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
| --- cleavage 766 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
| --- cleavage 769 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
| --- cleavage 770 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
| --- cleavage 773 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
| --- cleavage 774 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
| --- cleavage 778 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
| --- cleavage 784 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
| --- cleavage 785 (inside Integrin beta cytoplasmic domain 747..791) --- | ||||
3. Sequence Information
Fasta Sequence: SB0062.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
* Cleavage Information
10 [sites] cleaved by Calpain 2
Source Reference: [PubMed ID: 10571053] Pfaff M, Du X, Ginsberg MH, Calpain cleavage of integrin beta cytoplasmic domains. FEBS Lett. 1999 Oct 22;460(1):17-22.
Cleavage sites (±10aa)
[Site 1] EIYDRREYSR760-FEKEQQQLNW
Arg760 
Phe
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu751 | Ile752 | Tyr753 | Asp754 | Arg755 | Arg756 | Glu757 | Tyr758 | Ser759 | Arg760 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Phe761 | Glu762 | Lys763 | Glu764 | Gln765 | Gln766 | Gln767 | Leu768 | Asn769 | Trp770 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| CVGGIVAVGLGLVLAYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRF |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 132.00 | 10 | integrin, beta 7 |
| 2 | Pan troglodytes | 132.00 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 3 | N/A | 126.00 | 25 | integrin beta-7 subunit |
| 4 | Mus musculus | 126.00 | 12 | integrin beta 7 |
| 5 | Mus sp. | 126.00 | 1 | beta 7 integrin |
| 6 | Rattus norvegicus | 125.00 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 120.00 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Ictalurus punctatus | 72.40 | 2 | beta-1 integrin |
| 9 | Gallus gallus | 66.20 | 3 | integrin, beta 2 |
| 10 | synthetic construct | 63.50 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 11 | Homo sapiens | 63.50 | 1 | integrin, beta 2 precursor |
| 12 | Danio rerio | 63.20 | 6 | integrin, beta 1b.1 |
| 13 | Tetraodon nigroviridis | 62.00 | 6 | unnamed protein product |
| 14 | Oryctolagus cuniculus | 62.00 | 1 | integrin beta 1 |
| 15 | Bos taurus | 61.60 | 7 | integrin beta 1 |
| 16 | Sus scrofa | 61.60 | 3 | integrin beta-1 subunit |
| 17 | Xenopus laevis | 61.60 | 2 | integrin beta-1 subunit |
| 18 | Pongo pygmaeus | 61.60 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 19 | Pseudoplusia includens | 61.60 | 1 | integrin beta 1 |
| 20 | Xenopus laevis | 61.20 | 1 | hypothetical protein LOC379708 |
| 21 | Crassostrea gigas | 58.90 | 1 | integrin beta cgh |
| 22 | Felis catus | 58.90 | 1 | integrin beta 1 |
| 23 | Oryctolagus cuniculus | 58.20 | 1 | glycoprotein IIIa |
| 24 | Sus scrofa | 57.40 | 1 | integrin beta chain, beta 3 |
| 25 | Mus musculus | 57.40 | 1 | integrin beta 3 precursor |
| 26 | mice, Peptide Partial, 680 aa | 57.40 | 1 | beta 3 integrin, GPIIIA |
| 27 | rats, Peptide Partial, 723 aa | 57.40 | 1 | beta 3 integrin, GPIIIA |
| 28 | Canis lupus familiaris | 57.40 | 1 | integrin beta chain, beta 3 |
| 29 | Anopheles gambiae | 57.00 | 2 | integrin beta subunit |
| 30 | Anopheles gambiae str. PEST | 57.00 | 1 | integrin beta subunit (AGAP000815-PA) |
| 31 | Pacifastacus leniusculus | 53.50 | 1 | integrin |
| 32 | Drosophila melanogaster | 52.80 | 1 | myospheroid CG1560-PA |
| 33 | Podocoryne carnea | 52.80 | 1 | AF308652_1 integrin beta chain |
| 34 | Ovis aries | 51.20 | 2 | antigen CD18 |
| 35 | Ovis canadensis | 51.20 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 36 | Strongylocentrotus purpuratus | 50.80 | 3 | integrin beta L subunit |
| 37 | Gallus gallus | 50.40 | 2 | integrin, beta 3 precursor |
| 38 | Sigmodon hispidus | 48.90 | 1 | AF445415_1 integrin beta-2 precursor |
| 39 | Halocynthia roretzi | 47.80 | 2 | integrin beta Hr2 precursor |
| 40 | Schistosoma japonicum | 46.20 | 1 | SJCHGC06221 protein |
| 41 | Acropora millepora | 44.70 | 1 | integrin subunit betaCn1 |
| 42 | Lytechinus variegatus | 43.90 | 1 | beta-C integrin subunit |
| 43 | Caenorhabditis briggsae | 42.40 | 1 | Hypothetical protein CBG03601 |
| 44 | Anopheles gambiae str. PEST | 42.00 | 1 | AGAP010233-PA |
| 45 | Caenorhabditis elegans | 41.60 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 46 | Biomphalaria glabrata | 40.80 | 1 | beta integrin subunit |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 |
| Pan troglodytes | Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 |
| N/A | Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | |||||||||||||||||||||||||| |#|||||||||||||+|||||||||||+|||| Sbjct 729 CTGGIVAVGLGLVLAYRLSVEIYDRREYRR#FEKEQQQLNWKQDNNPLYKSAITTTVNPRF 788 |
| Mus musculus | Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | |||||||||||||||||||||||||| |#|||||||||||||+|||||||||||+|||| Sbjct 730 CTGGIVAVGLGLVLAYRLSVEIYDRREYRR#FEKEQQQLNWKQDNNPLYKSAITTTVNPRF 789 |
| Mus sp. | Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | |||||||||||||||||||||||||| |#|||||||||||||+|||||||||||+|||| Sbjct 730 CTGGIVAVGLGLVLAYRLSVEIYDRREYRR#FEKEQQQLNWKQDNNPLYKSAITTTVNPRF 789 |
| Rattus norvegicus | Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 |||||||||||||||||||||+||| ||||#||||+||||||||||||||||+|||+|||| Sbjct 564 CVGGIVAVGLGLVLAYRLSVEVYDRLEYSR#FEKERQQLNWKQDSNPLYKSAVTTTVNPRF 623 |
| Canis familiaris | Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 |||||||||||||||||||||||||||+||#|||||+ |||||++||||+||||||+||+| Sbjct 663 CVGGIVAVGLGLVLAYRLSVEIYDRREFSR#FEKEQKHLNWKQENNPLYRSAITTTVNPQF 722 |
| Ictalurus punctatus | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|| |+ ++| + |+||||+++#||||+ | ||+||||+|| +||++ Sbjct 746 VAGIVLIGLALLFIWKLLMIIHDRREFAK#FEKEKMNAKWDAGENPIYKSAVTTVVNPKY 804 |
| Gallus gallus | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 + |+ +|| |+| +|| ||+||||| |#||||+ + | + |||+||| || +|||| Sbjct 711 IAGVALIGLLLLLTWRLLTEIFDRREYRR#FEKEKSKAKWNEADNPLFKSATTTVMNPRF 769 |
| synthetic construct | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|+ |++ ++ + + | ||| |#||||+ + | | |||+||| || +||+| Sbjct 709 VAGIVLIGILLLVIWKALIHLSDLREYRR#FEKEKLKSQWNND-NPLFKSATTTVMNPKF 766 |
| Homo sapiens | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|+ |++ ++ + + | ||| |#||||+ + | | |||+||| || +||+| Sbjct 709 VAGIVLIGILLLVIWKALIHLSDLREYRR#FEKEKLKSQWNND-NPLFKSATTTVMNPKF 766 |
| Danio rerio | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|| |+| ++| + |+||||+ +#||||+ | ||+||||+|| +|||+ Sbjct 726 VAGIVLIGLALLLIWKLLMVIHDRREFDK#FEKEKNNAKWDTGENPIYKSAVTTVVNPRY 784 |
| Tetraodon nigroviridis | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|| |+| ++| + |+||||+++#||||+ | ||+||||+|| +||++ Sbjct 810 VAGIVLIGLALLLIWKLLMIIHDRREFAK#FEKEKMNAKWDTGENPIYKSAVTTVVNPKY 868 |
| Oryctolagus cuniculus | Query 731 CVGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|| |+| ++| + |+||||+++#||||+ | ||+||||+|| +||++ Sbjct 1 VVAGIVLIGLALLLIWKLLMIIHDRREFAK#FEKEKMNAKWDTGENPIYKSAVTTVVNPKY 60 |
| Bos taurus | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|| |+| ++| + |+||||+++#||||+ | ||+||||+|| +||++ Sbjct 737 VAGIVLIGLALLLIWKLLMIIHDRREFAK#FEKEKMNAKWDTGENPIYKSAVTTVVNPKY 795 |
| Sus scrofa | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|| |+| ++| + |+||||+++#||||+ | ||+||||+|| +||++ Sbjct 737 VAGIVLIGLALLLIWKLLMIIHDRREFAK#FEKEKMNAKWDTGENPIYKSAVTTVVNPKY 795 |
| Xenopus laevis | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|| |+| ++| + |+||||+++#||||+ | ||+||||+|| +||++ Sbjct 737 VAGIVLIGLALLLIWKLLMIIHDRREFAK#FEKEKMNAKWDTGENPIYKSAVTTVVNPKY 795 |
| Pongo pygmaeus | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|| |+| ++| + |+||||+++#||||+ | ||+||||+|| +||++ Sbjct 737 VAGIVLIGLALLLIWKLLMIIHDRREFAK#FEKEKMNAKWDTGENPIYKSAVTTVVNPKY 795 |
| Pseudoplusia includens | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 + || ||| |++ ++++ +||||++|#||||+ | ||+|| | +| || + Sbjct 776 IAAIVLVGLALLMLWKMATTSHDRREFAR#FEKERMMAKWDTGENPIYKQATSTFKNPTY 834 |
| Xenopus laevis | Query 733 GGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 |++ +|| ++ +++ || || || |#||||+ | |||| +| || || | Sbjct 712 AGVIFIGLACLIIWKIITEIKDRNEYQR#FEKERMNSKWNPGHNPLYHNATTTVQNPNF 769 |
| Crassostrea gigas | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 + ||| |+ |+| ++| | |+|| +|#|||| | ||+|| | +| +|| + Sbjct 739 IAGIVFFGIILLLIWKLFTTISDKRELAR#FEKEAMNARWDTGENPIYKQATSTFVNPTY 797 |
| Felis catus | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | ||| +|| |+| ++| + |+| ||+++#||||+ | ||+||||+|| +||++ Sbjct 737 VAGIVLIGLALLLIWKLLMIIHDTREFAK#FEKEKMNAKWDTGENPIYKSAVTTVVNPKY 795 |
| Oryctolagus cuniculus | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTIN 787 +| |+ +| |+| ++| + |+||+|+++#||+|+ + | +||||| | +| | Sbjct 727 MGAILLIGFALLLIWKLLITIHDRKEFAK#FEEERARAKWDTANNPLYKEATSTFTN 782 |
| Sus scrofa | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTIN 787 +| |+ +|| +| ++| + |+||+|+++#||+|+ + | +||||| | +| | Sbjct 723 MGAILLIGLATLLIWKLLITIHDRKEFAK#FEEERARAKWDTANNPLYKEATSTFTN 778 |
| Mus musculus | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTIN 787 +| |+ +|| +| ++| + |+||+|+++#||+|+ + | +||||| | +| | Sbjct 726 MGAILLIGLATLLIWKLLITIHDRKEFAK#FEEERARAKWDTANNPLYKEATSTFTN 781 |
| mice, Peptide Partial, 680 aa | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTIN 787 +| |+ +|| +| ++| + |+||+|+++#||+|+ + | +||||| | +| | Sbjct 623 MGAILLIGLATLLIWKLLITIHDRKEFAK#FEEERARAKWDTANNPLYKEATSTFTN 678 |
| rats, Peptide Partial, 723 aa | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTIN 787 +| |+ +|| +| ++| + |+||+|+++#||+|+ + | +||||| | +| | Sbjct 662 MGAILLIGLATLLIWKLLITIHDRKEFAK#FEEERARAKWDTANNPLYKEATSTFTN 717 |
| Canis lupus familiaris | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTIN 787 +| |+ +|| +| ++| + |+||+|+++#||+|+ + | +||||| | +| | Sbjct 723 MGAILLIGLATLLIWKLLITIHDRKEFAK#FEEERARAKWDTANNPLYKEATSTFTN 778 |
| Anopheles gambiae | Query 739 GLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 |+ ++| +++ |+||||++|#||||+ | ||+|| | || || + Sbjct 783 GMAVLLLWKVLTSIHDRREFAR#FEKERMMAKWDTGENPIYKQATTTFKNPTY 834 |
| Anopheles gambiae str. PEST | Query 739 GLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 |+ ++| +++ |+||||++|#||||+ | ||+|| | || || + Sbjct 783 GMAVLLLWKVLTSIHDRREFAR#FEKERMMAKWDTGENPIYKQATTTFKNPTY 834 |
| Pacifastacus leniusculus | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | |||+|| +| ++| ++|||||++#||||++ + |+ ||||||| || || | Sbjct 739 VAAIVAIGLLTLLIWKLLTTLHDRREYAK#FEKERKLPSGKRAENPLYKSAKTTFQNPAF 797 |
| Drosophila melanogaster | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 + || ||| ++| ++| |+||||++|#||||+ | ||+|| | +| || + Sbjct 785 IAAIVLVGLAILLLWKLLTTIHDRREFAR#FEKERMNAKWDTGENPIYKQATSTFKNPMY 843 |
| Podocoryne carnea | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 + ||| +|| |+| ++| | ||||+++#|||++| | ||+|| | +| || + Sbjct 720 IAGIVGIGLALLLIWKLLATIQDRREFAK#FEKDRQNPKWDSGENPIYKKATSTFQNPMY 778 |
| Ovis aries | Query 746 YRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 ++ + | ||| |#||||+ + | | |||+||| || +||+| Sbjct 724 WKALTHLSDLREYHR#FEKEKLKSQWNND-NPLFKSATTTVMNPKF 767 |
| Ovis canadensis | Query 746 YRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 ++ + | ||| |#||||+ + | | |||+||| || +||+| Sbjct 724 WKALTHLSDLREYHR#FEKEKLKSQWNND-NPLFKSATTTVMNPKF 767 |
| Strongylocentrotus purpuratus | Query 742 LVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 | |+|| + |+|||++#+| + ++ | | ||+|||+ || || + Sbjct 752 LARAWRLYTYVQDKREYAQ#WENDCKKAQWDQSDNPIYKSSTTTFKNPTY 800 |
| Gallus gallus | Query 746 YRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTIN 787 ++| + |+||||++|#||+|+ + | +||||| | +| | Sbjct 733 WKLLITIHDRREFAR#FEEEKARAKWDTGNNPLYKEATSTFTN 774 |
| Sigmodon hispidus | Query 746 YRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 ++ + | ||| #||||+ + | | |||+||| || +||+| Sbjct 723 WKALTHLTDLREYRH#FEKEKLKSQWNND-NPLFKSATTTVMNPKF 766 |
| Halocynthia roretzi | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 || +| +|+ ++ +++ + |+||| +#|+||+ | + ||+| +| + || | Sbjct 773 VGAVVLIGIIALIIWKVIQTLRDKREYEK#FKKEEDLRKWTKGENPVYVNASSKFDNPMF 831 |
| Schistosoma japonicum | Query 732 VGGIVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 + || || |+| |+| + | |||| + #|+++ + + |+ ||+++| | +|| | Sbjct 225 IAAIVLGGLILLLIYKLVITIDDRRELAN#FKQQGENMRWEMAENPIFESPTTNVLNPTF 283 |
| Acropora millepora | Query 754 DRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 || || +#||+|+ | ++ ||||++| || || + Sbjct 751 DRIEYQK#FERERMHSKWTREKNPLYQAAKTTFENPTY 787 |
| Lytechinus variegatus | Query 752 IYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 |+||||+ #||||+ |+ ||+|| + + || + Sbjct 765 IHDRREFQN#FEKERANATWEGGENPIYKPSTSVFKNPTY 803 |
| Caenorhabditis briggsae | Query 753 YDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 +|| ||++#| |+ | + ||+|| | || || + Sbjct 768 HDRAEYAK#FNNERLMAKWDTNENPIYKQATTTFKNPVY 805 |
| Anopheles gambiae str. PEST | Query 735 IVAVGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAIT 783 |+ || ++ || + ||+ +++#||||++| | +||||| |+ Sbjct 742 IIIGGLLMLFCYRCKIMYDDRKMFAK#FEKEREQETKYQMESPLYKSPIS 790 |
| Caenorhabditis elegans | Query 753 YDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 +|| ||+ #| |+ | + ||+|| | || || + Sbjct 767 HDRSEYAT#FNNERLMAKWDTNENPIYKQATTTFKNPVY 804 |
| Biomphalaria glabrata | Query 738 VGLGLVLAYRLSVEIYDRREYSR#FEKEQQQLNWKQDSNPLYKSAITTTINPRF 790 ||| |+| ++| |+| ||+++#||||+| | ||+|| | +| || + Sbjct 733 VGLFLLLLWKLLTFIHDTREFAK#FEKERQNAKWDTGENPIYKQATSTFKNPTY 785 |
[Site 2] REYSRFEKEQ765-QQLNWKQDSN
Gln765 Gln
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Arg756 | Glu757 | Tyr758 | Ser759 | Arg760 | Phe761 | Glu762 | Lys763 | Glu764 | Gln765 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Gln766 | Gln767 | Leu768 | Asn769 | Trp770 | Lys771 | Gln772 | Asp773 | Ser774 | Asn775 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| VAVGLGLVLAYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADS |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 130.00 | 10 | integrin, beta 7 |
| 2 | Pan troglodytes | 130.00 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 3 | N/A | 119.00 | 24 | integrin beta-7 subunit |
| 4 | Mus musculus | 119.00 | 12 | integrin beta 7 |
| 5 | Mus sp. | 119.00 | 1 | beta 7 integrin |
| 6 | Rattus norvegicus | 115.00 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 114.00 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Ictalurus punctatus | 67.40 | 2 | beta-1 integrin |
| 9 | Gallus gallus | 64.30 | 3 | integrin, beta 2 |
| 10 | synthetic construct | 60.10 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 11 | Homo sapiens | 60.10 | 1 | integrin, beta 2 precursor |
| 12 | Danio rerio | 59.70 | 6 | integrin, beta 1b.1 |
| 13 | Pseudoplusia includens | 58.90 | 1 | integrin beta 1 |
| 14 | Bos taurus | 58.50 | 7 | integrin beta 1 |
| 15 | Tetraodon nigroviridis | 58.50 | 6 | unnamed protein product |
| 16 | Sus scrofa | 58.50 | 3 | integrin beta-1 subunit |
| 17 | Xenopus laevis | 58.50 | 2 | integrin beta-1 subunit |
| 18 | Pongo pygmaeus | 58.50 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 19 | Oryctolagus cuniculus | 57.80 | 1 | integrin beta 1 |
| 20 | Xenopus laevis | 57.80 | 1 | hypothetical protein LOC379708 |
| 21 | Anopheles gambiae | 57.40 | 2 | integrin beta subunit |
| 22 | Anopheles gambiae str. PEST | 57.40 | 1 | integrin beta subunit (AGAP000815-PA) |
| 23 | Felis catus | 55.80 | 1 | integrin beta 1 |
| 24 | Crassostrea gigas | 55.10 | 1 | integrin beta cgh |
| 25 | Oryctolagus cuniculus | 53.90 | 1 | glycoprotein IIIa |
| 26 | Ovis aries | 53.50 | 2 | antigen CD18 |
| 27 | Ovis canadensis | 53.50 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 28 | Sus scrofa | 53.10 | 1 | integrin beta chain, beta 3 |
| 29 | Mus musculus | 53.10 | 1 | integrin beta 3 precursor |
| 30 | Canis lupus familiaris | 53.10 | 1 | integrin beta chain, beta 3 |
| 31 | mice, Peptide Partial, 680 aa | 53.10 | 1 | beta 3 integrin, GPIIIA |
| 32 | rats, Peptide Partial, 723 aa | 53.10 | 1 | beta 3 integrin, GPIIIA |
| 33 | Sigmodon hispidus | 51.20 | 1 | AF445415_1 integrin beta-2 precursor |
| 34 | Strongylocentrotus purpuratus | 50.80 | 3 | integrin beta L subunit |
| 35 | Pacifastacus leniusculus | 50.80 | 1 | integrin |
| 36 | Gallus gallus | 50.40 | 2 | integrin, beta 3 precursor |
| 37 | Drosophila melanogaster | 50.10 | 1 | myospheroid CG1560-PA |
| 38 | Schistosoma japonicum | 49.30 | 1 | SJCHGC06221 protein |
| 39 | Biomphalaria glabrata | 48.50 | 1 | beta integrin subunit |
| 40 | Podocoryne carnea | 47.80 | 1 | AF308652_1 integrin beta chain |
| 41 | Acropora millepora | 45.10 | 1 | integrin subunit betaCn1 |
| 42 | Lytechinus variegatus | 43.90 | 1 | beta-C integrin subunit |
| 43 | Halocynthia roretzi | 42.70 | 2 | integrin beta Hr2 precursor |
| 44 | Caenorhabditis briggsae | 42.40 | 1 | Hypothetical protein CBG03601 |
| 45 | Caenorhabditis elegans | 41.60 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 46 | Anopheles gambiae str. PEST | 40.80 | 1 | AGAP010233-PA |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEADS 795 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEADS 795 |
| Pan troglodytes | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEADS 795 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEADS 795 |
| N/A | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 ||||||||||||||||||||||| ||||||#||||||||+|||||||||||+||||| Sbjct 734 VAVGLGLVLAYRLSVEIYDRREYRRFEKEQ#QQLNWKQDNNPLYKSAITTTVNPRFQ 789 |
| Mus musculus | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 ||||||||||||||||||||||| ||||||#||||||||+|||||||||||+||||| Sbjct 735 VAVGLGLVLAYRLSVEIYDRREYRRFEKEQ#QQLNWKQDNNPLYKSAITTTVNPRFQ 790 |
| Mus sp. | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 ||||||||||||||||||||||| ||||||#||||||||+|||||||||||+||||| Sbjct 735 VAVGLGLVLAYRLSVEIYDRREYRRFEKEQ#QQLNWKQDNNPLYKSAITTTVNPRFQ 790 |
| Rattus norvegicus | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 ||||||||||||||||+||| ||||||||+#||||||||||||||||+|||+||||| Sbjct 569 VAVGLGLVLAYRLSVEVYDRLEYSRFEKER#QQLNWKQDSNPLYKSAVTTTVNPRFQ 624 |
| Canis familiaris | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEADS 795 ||||||||||||||||||||||+|||||||#+ |||||++||||+||||||+||+||| | Sbjct 668 VAVGLGLVLAYRLSVEIYDRREFSRFEKEQ#KHLNWKQENNPLYRSAITTTVNPQFQETGS 727 |
| Ictalurus punctatus | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 | +|| |+ ++| + |+||||+++||||+# | ||+||||+|| +||+++ Sbjct 750 VLIGLALLFIWKLLMIIHDRREFAKFEKEK#MNAKWDAGENPIYKSAVTTVVNPKYE 805 |
| Gallus gallus | Query 751 EIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 ||+||||| |||||+# + | + |||+||| || +|||| Sbjct 730 EIFDRREYRRFEKEK#SKAKWNEADNPLFKSATTTVMNPRF 769 |
| synthetic construct | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEA 793 | +|+ |++ ++ + + | ||| |||||+# + | | |||+||| || +||+| |+ Sbjct 713 VLIGILLLVIWKALIHLSDLREYRRFEKEK#LKSQWNND-NPLFKSATTTVMNPKFAES 769 |
| Homo sapiens | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEA 793 | +|+ |++ ++ + + | ||| |||||+# + | | |||+||| || +||+| |+ Sbjct 713 VLIGILLLVIWKALIHLSDLREYRRFEKEK#LKSQWNND-NPLFKSATTTVMNPKFAES 769 |
| Danio rerio | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+ +||||+# | ||+||||+|| +|||++ Sbjct 746 IHDRREFDKFEKEK#NNAKWDTGENPIYKSAVTTVVNPRYE 785 |
| Pseudoplusia includens | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 | ||| |++ ++++ +||||++|||||+# | ||+|| | +| || + Sbjct 780 VLVGLALLMLWKMATTSHDRREFARFEKER#MMAKWDTGENPIYKQATSTFKNPTY 834 |
| Bos taurus | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+# | ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEK#MNAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Tetraodon nigroviridis | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+# | ||+||||+|| +||+++ Sbjct 750 IHDRREFAKFEKEK#MNAKWDTGENPIYKSAVTTVVNPKYE 789 |
| Sus scrofa | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+# | ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEK#MNAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Xenopus laevis | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+# | ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEK#MNAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Pongo pygmaeus | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+# | ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEK#MNAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Oryctolagus cuniculus | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+# | ||+||||+|| +||+++ Sbjct 22 IHDRREFAKFEKEK#MNAKWDTGENPIYKSAVTTVVNPKYE 61 |
| Xenopus laevis | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 + +|| ++ +++ || || || |||||+# | |||| +| || || | Sbjct 715 IFIGLACLIIWKIITEIKDRNEYQRFEKER#MNSKWNPGHNPLYHNATTTVQNPNF 769 |
| Anopheles gambiae | Query 739 GLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 |+ ++| +++ |+||||++|||||+# | ||+|| | || || + Sbjct 783 GMAVLLLWKVLTSIHDRREFARFEKER#MMAKWDTGENPIYKQATTTFKNPTY 834 |
| Anopheles gambiae str. PEST | Query 739 GLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 |+ ++| +++ |+||||++|||||+# | ||+|| | || || + Sbjct 783 GMAVLLLWKVLTSIHDRREFARFEKER#MMAKWDTGENPIYKQATTTFKNPTY 834 |
| Felis catus | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 |+| ||+++||||+# | ||+||||+|| +||+++ Sbjct 757 IHDTREFAKFEKEK#MNAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Crassostrea gigas | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQE 792 | |+ |+| ++| | |+|| +||||| # | ||+|| | +| +|| +++ Sbjct 743 VFFGIILLLIWKLFTTISDKRELARFEKEA#MNARWDTGENPIYKQATSTFVNPTYRQ 799 |
| Oryctolagus cuniculus | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 +| |+| ++| + |+||+|+++||+|+# + | +||||| | +| | ++ Sbjct 733 IGFALLLIWKLLITIHDRKEFAKFEEER#ARAKWDTANNPLYKEATSTFTNITYR 786 |
| Ovis aries | Query 746 YRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+# + | | |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEK#LKSQWNND-NPLFKSATTTVMNPKFAES 770 |
| Ovis canadensis | Query 746 YRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+# + | | |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEK#LKSQWNND-NPLFKSATTTVMNPKFAES 770 |
| Sus scrofa | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 +|| +| ++| + |+||+|+++||+|+# + | +||||| | +| | ++ Sbjct 729 IGLATLLIWKLLITIHDRKEFAKFEEER#ARAKWDTANNPLYKEATSTFTNITYR 782 |
| Mus musculus | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 +|| +| ++| + |+||+|+++||+|+# + | +||||| | +| | ++ Sbjct 732 IGLATLLIWKLLITIHDRKEFAKFEEER#ARAKWDTANNPLYKEATSTFTNITYR 785 |
| Canis lupus familiaris | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 +|| +| ++| + |+||+|+++||+|+# + | +||||| | +| | ++ Sbjct 729 IGLATLLIWKLLITIHDRKEFAKFEEER#ARAKWDTANNPLYKEATSTFTNITYR 782 |
| mice, Peptide Partial, 680 aa | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTIN 787 +|| +| ++| + |+||+|+++||+|+# + | +||||| | +| | Sbjct 629 IGLATLLIWKLLITIHDRKEFAKFEEER#ARAKWDTANNPLYKEATSTFTN 678 |
| rats, Peptide Partial, 723 aa | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 +|| +| ++| + |+||+|+++||+|+# + | +||||| | +| | ++ Sbjct 668 IGLATLLIWKLLITIHDRKEFAKFEEER#ARAKWDTANNPLYKEATSTFTNITYR 721 |
| Sigmodon hispidus | Query 746 YRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| ||||+# + | | |||+||| || +||+| |+ Sbjct 723 WKALTHLTDLREYRHFEKEK#LKSQWNND-NPLFKSATTTVMNPKFAES 769 |
| Strongylocentrotus purpuratus | Query 742 LVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 | |+|| + |+|||+++| + #++ | | ||+|||+ || || + Sbjct 752 LARAWRLYTYVQDKREYAQWENDC#KKAQWDQSDNPIYKSSTTTFKNPTY 800 |
| Pacifastacus leniusculus | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQEA 793 ||+|| +| ++| ++|||||++||||+#+ + |+ ||||||| || || | ++ Sbjct 743 VAIGLLTLLIWKLLTTLHDRREYAKFEKER#KLPSGKRAENPLYKSAKTTFQNPAFAQS 800 |
| Gallus gallus | Query 746 YRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQ 791 ++| + |+||||++|||+|+# + | +||||| | +| | ++ Sbjct 733 WKLLITIHDRREFARFEEEK#ARAKWDTGNNPLYKEATSTFTNITYR 778 |
| Drosophila melanogaster | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 |+||||++|||||+# | ||+|| | +| || + Sbjct 805 IHDRREFARFEKER#MNAKWDTGENPIYKQATSTFKNPMY 843 |
| Schistosoma japonicum | Query 746 YRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRFQE 792 |+| + | |||| + |+++ #+ + |+ ||+++| | +|| |+| Sbjct 239 YKLVITIDDRRELANFKQQG#ENMRWEMAENPIFESPTTNVLNPTFEE 285 |
| Biomphalaria glabrata | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 |+| ||+++||||+#| | ||+|| | +| || + Sbjct 747 IHDTREFAKFEKER#QNAKWDTGENPIYKQATSTFKNPTY 785 |
| Podocoryne carnea | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 | ||||+++|||++#| | ||+|| | +| || + Sbjct 740 IQDRREFAKFEKDR#QNPKWDSGENPIYKKATSTFQNPMY 778 |
| Acropora millepora | Query 754 DRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 || || +||+|+# | ++ ||||++| || || + Sbjct 751 DRIEYQKFERER#MHSKWTREKNPLYQAAKTTFENPTY 787 |
| Lytechinus variegatus | Query 752 IYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 |+||||+ ||||+# |+ ||+|| + + || + Sbjct 765 IHDRREFQNFEKER#ANATWEGGENPIYKPSTSVFKNPTY 803 |
| Halocynthia roretzi | Query 736 VAVGLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 | +|+ ++ +++ + |+||| +|+||+# | + ||+| +| + || | Sbjct 777 VLIGIIALIIWKVIQTLRDKREYEKFKKEE#DLRKWTKGENPVYVNASSKFDNPMF 831 |
| Caenorhabditis briggsae | Query 753 YDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 +|| ||++| |+# | + ||+|| | || || + Sbjct 768 HDRAEYAKFNNER#LMAKWDTNENPIYKQATTTFKNPVY 805 |
| Caenorhabditis elegans | Query 753 YDRREYSRFEKEQ#QQLNWKQDSNPLYKSAITTTINPRF 790 +|| ||+ | |+# | + ||+|| | || || + Sbjct 767 HDRSEYATFNNER#LMAKWDTNENPIYKQATTTFKNPVY 804 |
| Anopheles gambiae str. PEST | Query 739 GLGLVLAYRLSVEIYDRREYSRFEKEQ#QQLNWKQDSNPLYKSAIT 783 || ++ || + ||+ +++||||+#+| | +||||| |+ Sbjct 746 GLLMLFCYRCKIMYDDRKMFAKFEKER#EQETKYQMESPLYKSPIS 790 |
[Site 3] EYSRFEKEQQ766-QLNWKQDSNP
Gln766 Gln
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu757 | Tyr758 | Ser759 | Arg760 | Phe761 | Glu762 | Lys763 | Glu764 | Gln765 | Gln766 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Gln767 | Leu768 | Asn769 | Trp770 | Lys771 | Gln772 | Asp773 | Ser774 | Asn775 | Pro776 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| AVGLGLVLAYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADSP |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 132.00 | 10 | integrin, beta 7 |
| 2 | Pan troglodytes | 132.00 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 3 | N/A | 117.00 | 24 | integrin beta-7 subunit |
| 4 | Mus musculus | 117.00 | 12 | integrin beta 7 |
| 5 | Mus sp. | 117.00 | 1 | beta 7 integrin |
| 6 | Rattus norvegicus | 114.00 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 112.00 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Ictalurus punctatus | 66.20 | 2 | beta-1 integrin |
| 9 | Gallus gallus | 64.30 | 3 | integrin, beta 2 |
| 10 | Danio rerio | 59.70 | 6 | integrin, beta 1b.1 |
| 11 | synthetic construct | 58.90 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 12 | Homo sapiens | 58.90 | 1 | integrin, beta 2 precursor |
| 13 | Bos taurus | 58.50 | 7 | integrin beta 1 |
| 14 | Tetraodon nigroviridis | 58.50 | 6 | unnamed protein product |
| 15 | Sus scrofa | 58.50 | 3 | integrin beta-1 subunit |
| 16 | Xenopus laevis | 58.50 | 2 | integrin beta-1 subunit |
| 17 | Pongo pygmaeus | 58.50 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 18 | Pseudoplusia includens | 57.80 | 1 | integrin beta 1 |
| 19 | Xenopus laevis | 57.80 | 1 | hypothetical protein LOC379708 |
| 20 | Oryctolagus cuniculus | 57.40 | 1 | integrin beta 1 |
| 21 | Anopheles gambiae | 57.00 | 2 | integrin beta subunit |
| 22 | Anopheles gambiae str. PEST | 57.00 | 1 | integrin beta subunit (AGAP000815-PA) |
| 23 | Felis catus | 55.80 | 1 | integrin beta 1 |
| 24 | Crassostrea gigas | 54.70 | 1 | integrin beta cgh |
| 25 | Oryctolagus cuniculus | 53.90 | 1 | glycoprotein IIIa |
| 26 | Ovis aries | 53.50 | 2 | antigen CD18 |
| 27 | Ovis canadensis | 53.50 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 28 | Canis lupus familiaris | 53.10 | 1 | integrin beta chain, beta 3 |
| 29 | rats, Peptide Partial, 723 aa | 53.10 | 1 | beta 3 integrin, GPIIIA |
| 30 | mice, Peptide Partial, 680 aa | 53.10 | 1 | beta 3 integrin, GPIIIA |
| 31 | Mus musculus | 53.10 | 1 | integrin beta 3 precursor |
| 32 | Sus scrofa | 53.10 | 1 | integrin beta chain, beta 3 |
| 33 | Sigmodon hispidus | 51.20 | 1 | AF445415_1 integrin beta-2 precursor |
| 34 | Strongylocentrotus purpuratus | 50.80 | 3 | integrin beta L subunit |
| 35 | Gallus gallus | 50.40 | 2 | integrin, beta 3 precursor |
| 36 | Pacifastacus leniusculus | 50.40 | 1 | integrin |
| 37 | Drosophila melanogaster | 50.10 | 1 | myospheroid CG1560-PA |
| 38 | Schistosoma japonicum | 49.30 | 1 | SJCHGC06221 protein |
| 39 | Biomphalaria glabrata | 48.50 | 1 | beta integrin subunit |
| 40 | Podocoryne carnea | 47.80 | 1 | AF308652_1 integrin beta chain |
| 41 | Acropora millepora | 45.10 | 1 | integrin subunit betaCn1 |
| 42 | Lytechinus variegatus | 43.90 | 1 | beta-C integrin subunit |
| 43 | Caenorhabditis briggsae | 42.40 | 1 | Hypothetical protein CBG03601 |
| 44 | Halocynthia roretzi | 41.60 | 2 | integrin beta Hr2 precursor |
| 45 | Caenorhabditis elegans | 41.60 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 46 | Anopheles gambiae str. PEST | 40.80 | 1 | AGAP010233-PA |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 737 AVGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEADSP 796 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 737 AVGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEADSP 796 |
| Pan troglodytes | Query 737 AVGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEADSP 796 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 737 AVGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEADSP 796 |
| N/A | Query 737 AVGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |||||||||||||||||||||| |||||||#|||||||+|||||||||||+||||| Sbjct 735 AVGLGLVLAYRLSVEIYDRREYRRFEKEQQ#QLNWKQDNNPLYKSAITTTVNPRFQ 789 |
| Mus musculus | Query 737 AVGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |||||||||||||||||||||| |||||||#|||||||+|||||||||||+||||| Sbjct 736 AVGLGLVLAYRLSVEIYDRREYRRFEKEQQ#QLNWKQDNNPLYKSAITTTVNPRFQ 790 |
| Mus sp. | Query 737 AVGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |||||||||||||||||||||| |||||||#|||||||+|||||||||||+||||| Sbjct 736 AVGLGLVLAYRLSVEIYDRREYRRFEKEQQ#QLNWKQDNNPLYKSAITTTVNPRFQ 790 |
| Rattus norvegicus | Query 737 AVGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |||||||||||||||+||| ||||||||+|#|||||||||||||||+|||+||||| Sbjct 570 AVGLGLVLAYRLSVEVYDRLEYSRFEKERQ#QLNWKQDSNPLYKSAVTTTVNPRFQ 624 |
| Canis familiaris | Query 737 AVGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEADS 795 |||||||||||||||||||||+|||||||+# |||||++||||+||||||+||+||| | Sbjct 669 AVGLGLVLAYRLSVEIYDRREFSRFEKEQK#HLNWKQENNPLYRSAITTTVNPQFQETGS 727 |
| Ictalurus punctatus | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 +|| |+ ++| + |+||||+++||||+ # | ||+||||+|| +||+++ Sbjct 752 IGLALLFIWKLLMIIHDRREFAKFEKEKM#NAKWDAGENPIYKSAVTTVVNPKYE 805 |
| Gallus gallus | Query 751 EIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 ||+||||| |||||+ #+ | + |||+||| || +|||| Sbjct 730 EIFDRREYRRFEKEKS#KAKWNEADNPLFKSATTTVMNPRF 769 |
| Danio rerio | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+ +||||+ # | ||+||||+|| +|||++ Sbjct 746 IHDRREFDKFEKEKN#NAKWDTGENPIYKSAVTTVVNPRYE 785 |
| synthetic construct | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEA 793 +|+ |++ ++ + + | ||| |||||+ #+ | | |||+||| || +||+| |+ Sbjct 715 IGILLLVIWKALIHLSDLREYRRFEKEKL#KSQWNND-NPLFKSATTTVMNPKFAES 769 |
| Homo sapiens | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEA 793 +|+ |++ ++ + + | ||| |||||+ #+ | | |||+||| || +||+| |+ Sbjct 715 IGILLLVIWKALIHLSDLREYRRFEKEKL#KSQWNND-NPLFKSATTTVMNPKFAES 769 |
| Bos taurus | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ # | ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Tetraodon nigroviridis | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ # | ||+||||+|| +||+++ Sbjct 750 IHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYE 789 |
| Sus scrofa | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ # | ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Xenopus laevis | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ # | ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Pongo pygmaeus | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ # | ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Pseudoplusia includens | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 ||| |++ ++++ +||||++|||||+ # | ||+|| | +| || + Sbjct 782 VGLALLMLWKMATTSHDRREFARFEKERM#MAKWDTGENPIYKQATSTFKNPTY 834 |
| Xenopus laevis | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 +|| ++ +++ || || || |||||+ # | |||| +| || || | Sbjct 717 IGLACLIIWKIITEIKDRNEYQRFEKERM#NSKWNPGHNPLYHNATTTVQNPNF 769 |
| Oryctolagus cuniculus | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ # | ||+||||+|| +||+++ Sbjct 22 IHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYE 61 |
| Anopheles gambiae | Query 739 GLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 |+ ++| +++ |+||||++|||||+ # | ||+|| | || || + Sbjct 783 GMAVLLLWKVLTSIHDRREFARFEKERM#MAKWDTGENPIYKQATTTFKNPTY 834 |
| Anopheles gambiae str. PEST | Query 739 GLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 |+ ++| +++ |+||||++|||||+ # | ||+|| | || || + Sbjct 783 GMAVLLLWKVLTSIHDRREFARFEKERM#MAKWDTGENPIYKQATTTFKNPTY 834 |
| Felis catus | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 |+| ||+++||||+ # | ||+||||+|| +||+++ Sbjct 757 IHDTREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYE 796 |
| Crassostrea gigas | Query 739 GLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQE 792 |+ |+| ++| | |+|| +||||| # | ||+|| | +| +|| +++ Sbjct 746 GIILLLIWKLFTTISDKRELARFEKEAM#NARWDTGENPIYKQATSTFVNPTYRQ 799 |
| Oryctolagus cuniculus | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 +| |+| ++| + |+||+|+++||+|+ #+ | +||||| | +| | ++ Sbjct 733 IGFALLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYR 786 |
| Ovis aries | Query 746 YRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+ #+ | | |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEKL#KSQWNND-NPLFKSATTTVMNPKFAES 770 |
| Ovis canadensis | Query 746 YRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+ #+ | | |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEKL#KSQWNND-NPLFKSATTTVMNPKFAES 770 |
| Canis lupus familiaris | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 +|| +| ++| + |+||+|+++||+|+ #+ | +||||| | +| | ++ Sbjct 729 IGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYR 782 |
| rats, Peptide Partial, 723 aa | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 +|| +| ++| + |+||+|+++||+|+ #+ | +||||| | +| | ++ Sbjct 668 IGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYR 721 |
| mice, Peptide Partial, 680 aa | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTIN 787 +|| +| ++| + |+||+|+++||+|+ #+ | +||||| | +| | Sbjct 629 IGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTN 678 |
| Mus musculus | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 +|| +| ++| + |+||+|+++||+|+ #+ | +||||| | +| | ++ Sbjct 732 IGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYR 785 |
| Sus scrofa | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 +|| +| ++| + |+||+|+++||+|+ #+ | +||||| | +| | ++ Sbjct 729 IGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYR 782 |
| Sigmodon hispidus | Query 746 YRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| ||||+ #+ | | |||+||| || +||+| |+ Sbjct 723 WKALTHLTDLREYRHFEKEKL#KSQWNND-NPLFKSATTTVMNPKFAES 769 |
| Strongylocentrotus purpuratus | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 | |+|| + |+|||+++| + +#+ | | ||+|||+ || || + Sbjct 752 LARAWRLYTYVQDKREYAQWENDCK#KAQWDQSDNPIYKSSTTTFKNPTY 800 |
| Gallus gallus | Query 746 YRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQ 791 ++| + |+||||++|||+|+ #+ | +||||| | +| | ++ Sbjct 733 WKLLITIHDRREFARFEEEKA#RAKWDTGNNPLYKEATSTFTNITYR 778 |
| Pacifastacus leniusculus | Query 753 YDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQEA 793 +|||||++||||++# + |+ ||||||| || || | ++ Sbjct 760 HDRREYAKFEKERK#LPSGKRAENPLYKSAKTTFQNPAFAQS 800 |
| Drosophila melanogaster | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 |+||||++|||||+ # | ||+|| | +| || + Sbjct 805 IHDRREFARFEKERM#NAKWDTGENPIYKQATSTFKNPMY 843 |
| Schistosoma japonicum | Query 746 YRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRFQE 792 |+| + | |||| + |+++ +# + |+ ||+++| | +|| |+| Sbjct 239 YKLVITIDDRRELANFKQQGE#NMRWEMAENPIFESPTTNVLNPTFEE 285 |
| Biomphalaria glabrata | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 |+| ||+++||||+|# | ||+|| | +| || + Sbjct 747 IHDTREFAKFEKERQ#NAKWDTGENPIYKQATSTFKNPTY 785 |
| Podocoryne carnea | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 | ||||+++|||++|# | ||+|| | +| || + Sbjct 740 IQDRREFAKFEKDRQ#NPKWDSGENPIYKKATSTFQNPMY 778 |
| Acropora millepora | Query 754 DRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 || || +||+|+ # | ++ ||||++| || || + Sbjct 751 DRIEYQKFERERM#HSKWTREKNPLYQAAKTTFENPTY 787 |
| Lytechinus variegatus | Query 752 IYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 |+||||+ ||||+ # |+ ||+|| + + || + Sbjct 765 IHDRREFQNFEKERA#NATWEGGENPIYKPSTSVFKNPTY 803 |
| Caenorhabditis briggsae | Query 753 YDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 +|| ||++| |+ # | + ||+|| | || || + Sbjct 768 HDRAEYAKFNNERL#MAKWDTNENPIYKQATTTFKNPVY 805 |
| Halocynthia roretzi | Query 738 VGLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 +|+ ++ +++ + |+||| +|+||+ # | + ||+| +| + || | Sbjct 779 IGIIALIIWKVIQTLRDKREYEKFKKEED#LRKWTKGENPVYVNASSKFDNPMF 831 |
| Caenorhabditis elegans | Query 753 YDRREYSRFEKEQQ#QLNWKQDSNPLYKSAITTTINPRF 790 +|| ||+ | |+ # | + ||+|| | || || + Sbjct 767 HDRSEYATFNNERL#MAKWDTNENPIYKQATTTFKNPVY 804 |
| Anopheles gambiae str. PEST | Query 739 GLGLVLAYRLSVEIYDRREYSRFEKEQQ#QLNWKQDSNPLYKSAIT 783 || ++ || + ||+ +++||||++#| | +||||| |+ Sbjct 746 GLLMLFCYRCKIMYDDRKMFAKFEKERE#QETKYQMESPLYKSPIS 790 |
[Site 4] RFEKEQQQLN769-WKQDSNPLYK
Asn769 Trp
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Arg760 | Phe761 | Glu762 | Lys763 | Glu764 | Gln765 | Gln766 | Gln767 | Leu768 | Asn769 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Trp770 | Lys771 | Gln772 | Asp773 | Ser774 | Asn775 | Pro776 | Leu777 | Tyr778 | Lys779 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LGLVLAYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADSPTL |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 130.00 | 10 | integrin, beta 7 |
| 2 | Pan troglodytes | 130.00 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 3 | N/A | 113.00 | 24 | integrin beta-7 subunit |
| 4 | Mus musculus | 113.00 | 12 | integrin beta 7 |
| 5 | Mus sp. | 113.00 | 1 | beta 7 integrin |
| 6 | Rattus norvegicus | 110.00 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 107.00 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Gallus gallus | 64.30 | 3 | integrin, beta 2 |
| 9 | Ictalurus punctatus | 63.20 | 2 | beta-1 integrin |
| 10 | Danio rerio | 59.70 | 6 | integrin, beta 1b.1 |
| 11 | Bos taurus | 58.50 | 7 | integrin beta 1 |
| 12 | Tetraodon nigroviridis | 58.50 | 6 | unnamed protein product |
| 13 | Sus scrofa | 58.50 | 3 | integrin beta-1 subunit |
| 14 | Xenopus laevis | 58.50 | 2 | integrin beta-1 subunit |
| 15 | Pongo pygmaeus | 58.50 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 16 | Oryctolagus cuniculus | 57.80 | 1 | integrin beta 1 |
| 17 | synthetic construct | 56.60 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 18 | Homo sapiens | 56.60 | 1 | integrin, beta 2 precursor |
| 19 | Felis catus | 55.80 | 1 | integrin beta 1 |
| 20 | Anopheles gambiae | 54.70 | 2 | integrin beta subunit |
| 21 | Anopheles gambiae str. PEST | 54.70 | 1 | integrin beta subunit (AGAP000815-PA) |
| 22 | Xenopus laevis | 54.30 | 1 | hypothetical protein LOC379708 |
| 23 | Pseudoplusia includens | 53.90 | 1 | integrin beta 1 |
| 24 | Ovis aries | 53.50 | 2 | antigen CD18 |
| 25 | Ovis canadensis | 53.50 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 26 | Crassostrea gigas | 53.10 | 1 | integrin beta cgh |
| 27 | Sigmodon hispidus | 51.20 | 1 | AF445415_1 integrin beta-2 precursor |
| 28 | Strongylocentrotus purpuratus | 50.80 | 3 | integrin beta L subunit |
| 29 | Gallus gallus | 50.40 | 2 | integrin, beta 3 precursor |
| 30 | Pacifastacus leniusculus | 50.40 | 1 | integrin |
| 31 | Oryctolagus cuniculus | 50.40 | 1 | glycoprotein IIIa |
| 32 | Drosophila melanogaster | 50.10 | 1 | myospheroid CG1560-PA |
| 33 | Canis lupus familiaris | 49.70 | 1 | integrin beta chain, beta 3 |
| 34 | rats, Peptide Partial, 723 aa | 49.70 | 1 | beta 3 integrin, GPIIIA |
| 35 | mice, Peptide Partial, 680 aa | 49.70 | 1 | beta 3 integrin, GPIIIA |
| 36 | Sus scrofa | 49.70 | 1 | integrin beta chain, beta 3 |
| 37 | Mus musculus | 49.70 | 1 | integrin beta 3 precursor |
| 38 | Schistosoma japonicum | 49.30 | 1 | SJCHGC06221 protein |
| 39 | Biomphalaria glabrata | 48.50 | 1 | beta integrin subunit |
| 40 | Podocoryne carnea | 47.80 | 1 | AF308652_1 integrin beta chain |
| 41 | Acropora millepora | 45.10 | 1 | integrin subunit betaCn1 |
| 42 | Lytechinus variegatus | 43.90 | 1 | beta-C integrin subunit |
| 43 | Caenorhabditis briggsae | 42.40 | 1 | Hypothetical protein CBG03601 |
| 44 | Caenorhabditis elegans | 41.60 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 45 | Halocynthia roretzi | 39.70 | 1 | integrin beta Hr2 precursor |
| 46 | Anopheles gambiae str. PEST | 38.10 | 1 | AGAP010233-PA |
| 47 | Cyprinus carpio | 36.20 | 2 | integrin beta2-chain |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||| Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEADSPTL 798 |
| Pan troglodytes | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||| Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEADSPTL 798 |
| N/A | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEAD--SPT 797 ||||||||||||||||||| ||||||||||#||||+|||||||||||+||||| + ||+ Sbjct 738 LGLVLAYRLSVEIYDRREYRRFEKEQQQLN#WKQDNNPLYKSAITTTVNPRFQGTNGRSPS 797 Query 798 L 798 | Query 798 L 798 |
| Mus musculus | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEAD--SPT 797 ||||||||||||||||||| ||||||||||#||||+|||||||||||+||||| + ||+ Sbjct 739 LGLVLAYRLSVEIYDRREYRRFEKEQQQLN#WKQDNNPLYKSAITTTVNPRFQGTNGRSPS 798 Query 798 L 798 | Query 798 L 798 |
| Mus sp. | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEAD--SPT 797 ||||||||||||||||||| ||||||||||#||||+|||||||||||+||||| + ||+ Sbjct 739 LGLVLAYRLSVEIYDRREYRRFEKEQQQLN#WKQDNNPLYKSAITTTVNPRFQGTNGRSPS 798 Query 798 L 798 | Query 798 L 798 |
| Rattus norvegicus | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEADSPTL 798 ||||||||||||+||| ||||||||+||||#||||||||||||+|||+||||| + +| Sbjct 573 LGLVLAYRLSVEVYDRLEYSRFEKERQQLN#WKQDSNPLYKSAVTTTVNPRFQGGNKQSL 631 |
| Canis familiaris | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEADS 795 ||||||||||||||||||+|||||||+ ||#|||++||||+||||||+||+||| | Sbjct 672 LGLVLAYRLSVEIYDRREFSRFEKEQKHLN#WKQENNPLYRSAITTTVNPQFQETGS 727 |
| Gallus gallus | Query 751 EIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 ||+||||| |||||+ + #| + |||+||| || +|||| Sbjct 730 EIFDRREYRRFEKEKSKAK#WNEADNPLFKSATTTVMNPRF 769 |
| Ictalurus punctatus | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 | |+ ++| + |+||||+++||||+ #| ||+||||+|| +||+++ Sbjct 754 LALLFIWKLLMIIHDRREFAKFEKEKMNAK#WDAGENPIYKSAVTTVVNPKYE 805 |
| Danio rerio | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 |+||||+ +||||+ #| ||+||||+|| +|||++ Sbjct 746 IHDRREFDKFEKEKNNAK#WDTGENPIYKSAVTTVVNPRYE 785 |
| Bos taurus | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ #| ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAK#WDTGENPIYKSAVTTVVNPKYE 796 |
| Tetraodon nigroviridis | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ #| ||+||||+|| +||+++ Sbjct 750 IHDRREFAKFEKEKMNAK#WDTGENPIYKSAVTTVVNPKYE 789 |
| Sus scrofa | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ #| ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAK#WDTGENPIYKSAVTTVVNPKYE 796 |
| Xenopus laevis | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ #| ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAK#WDTGENPIYKSAVTTVVNPKYE 796 |
| Pongo pygmaeus | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ #| ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAK#WDTGENPIYKSAVTTVVNPKYE 796 |
| Oryctolagus cuniculus | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ #| ||+||||+|| +||+++ Sbjct 22 IHDRREFAKFEKEKMNAK#WDTGENPIYKSAVTTVVNPKYE 61 |
| synthetic construct | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEA 793 |++ ++ + + | ||| |||||+ + #| | |||+||| || +||+| |+ Sbjct 719 LLVIWKALIHLSDLREYRRFEKEKLKSQ#WNND-NPLFKSATTTVMNPKFAES 769 |
| Homo sapiens | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEA 793 |++ ++ + + | ||| |||||+ + #| | |||+||| || +||+| |+ Sbjct 719 LLVIWKALIHLSDLREYRRFEKEKLKSQ#WNND-NPLFKSATTTVMNPKFAES 769 |
| Felis catus | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 |+| ||+++||||+ #| ||+||||+|| +||+++ Sbjct 757 IHDTREFAKFEKEKMNAK#WDTGENPIYKSAVTTVVNPKYE 796 |
| Anopheles gambiae | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 + ++| +++ |+||||++|||||+ #| ||+|| | || || + Sbjct 784 MAVLLLWKVLTSIHDRREFARFEKERMMAK#WDTGENPIYKQATTTFKNPTY 834 |
| Anopheles gambiae str. PEST | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 + ++| +++ |+||||++|||||+ #| ||+|| | || || + Sbjct 784 MAVLLLWKVLTSIHDRREFARFEKERMMAK#WDTGENPIYKQATTTFKNPTY 834 |
| Xenopus laevis | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 | ++ +++ || || || |||||+ #| |||| +| || || | Sbjct 719 LACLIIWKIITEIKDRNEYQRFEKERMNSK#WNPGHNPLYHNATTTVQNPNF 769 |
| Pseudoplusia includens | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 | |++ ++++ +||||++|||||+ #| ||+|| | +| || + Sbjct 784 LALLMLWKMATTSHDRREFARFEKERMMAK#WDTGENPIYKQATSTFKNPTY 834 |
| Ovis aries | Query 746 YRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+ + #| | |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEKLKSQ#WNND-NPLFKSATTTVMNPKFAES 770 |
| Ovis canadensis | Query 746 YRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+ + #| | |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEKLKSQ#WNND-NPLFKSATTTVMNPKFAES 770 |
| Crassostrea gigas | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQE 792 |+| ++| | |+|| +||||| #| ||+|| | +| +|| +++ Sbjct 749 LLLIWKLFTTISDKRELARFEKEAMNAR#WDTGENPIYKQATSTFVNPTYRQ 799 |
| Sigmodon hispidus | Query 746 YRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| ||||+ + #| | |||+||| || +||+| |+ Sbjct 723 WKALTHLTDLREYRHFEKEKLKSQ#WNND-NPLFKSATTTVMNPKFAES 769 |
| Strongylocentrotus purpuratus | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 | |+|| + |+|||+++| + ++ #| | ||+|||+ || || + Sbjct 752 LARAWRLYTYVQDKREYAQWENDCKKAQ#WDQSDNPIYKSSTTTFKNPTY 800 |
| Gallus gallus | Query 746 YRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 ++| + |+||||++|||+|+ + #| +||||| | +| | ++ Sbjct 733 WKLLITIHDRREFARFEEEKARAK#WDTGNNPLYKEATSTFTNITYR 778 |
| Pacifastacus leniusculus | Query 753 YDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQEA 793 +|||||++||||++ +# |+ ||||||| || || | ++ Sbjct 760 HDRREYAKFEKERKLPS#GKRAENPLYKSAKTTFQNPAFAQS 800 |
| Oryctolagus cuniculus | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 |+| ++| + |+||+|+++||+|+ + #| +||||| | +| | ++ Sbjct 735 FALLLIWKLLITIHDRKEFAKFEEERARAK#WDTANNPLYKEATSTFTNITYR 786 |
| Drosophila melanogaster | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 |+||||++|||||+ #| ||+|| | +| || + Sbjct 805 IHDRREFARFEKERMNAK#WDTGENPIYKQATSTFKNPMY 843 |
| Canis lupus familiaris | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 | +| ++| + |+||+|+++||+|+ + #| +||||| | +| | ++ Sbjct 731 LATLLIWKLLITIHDRKEFAKFEEERARAK#WDTANNPLYKEATSTFTNITYR 782 |
| rats, Peptide Partial, 723 aa | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 | +| ++| + |+||+|+++||+|+ + #| +||||| | +| | ++ Sbjct 670 LATLLIWKLLITIHDRKEFAKFEEERARAK#WDTANNPLYKEATSTFTNITYR 721 |
| mice, Peptide Partial, 680 aa | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTIN 787 | +| ++| + |+||+|+++||+|+ + #| +||||| | +| | Sbjct 631 LATLLIWKLLITIHDRKEFAKFEEERARAK#WDTANNPLYKEATSTFTN 678 |
| Sus scrofa | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 | +| ++| + |+||+|+++||+|+ + #| +||||| | +| | ++ Sbjct 731 LATLLIWKLLITIHDRKEFAKFEEERARAK#WDTANNPLYKEATSTFTNITYR 782 |
| Mus musculus | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQ 791 | +| ++| + |+||+|+++||+|+ + #| +||||| | +| | ++ Sbjct 734 LATLLIWKLLITIHDRKEFAKFEEERARAK#WDTANNPLYKEATSTFTNITYR 785 |
| Schistosoma japonicum | Query 746 YRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRFQE 792 |+| + | |||| + |+++ + + #|+ ||+++| | +|| |+| Sbjct 239 YKLVITIDDRRELANFKQQGENMR#WEMAENPIFESPTTNVLNPTFEE 285 |
| Biomphalaria glabrata | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 |+| ||+++||||+| #| ||+|| | +| || + Sbjct 747 IHDTREFAKFEKERQNAK#WDTGENPIYKQATSTFKNPTY 785 |
| Podocoryne carnea | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 | ||||+++|||++| #| ||+|| | +| || + Sbjct 740 IQDRREFAKFEKDRQNPK#WDSGENPIYKKATSTFQNPMY 778 |
| Acropora millepora | Query 754 DRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 || || +||+|+ #| ++ ||||++| || || + Sbjct 751 DRIEYQKFERERMHSK#WTREKNPLYQAAKTTFENPTY 787 |
| Lytechinus variegatus | Query 752 IYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 |+||||+ ||||+ #|+ ||+|| + + || + Sbjct 765 IHDRREFQNFEKERANAT#WEGGENPIYKPSTSVFKNPTY 803 |
| Caenorhabditis briggsae | Query 753 YDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 +|| ||++| |+ #| + ||+|| | || || + Sbjct 768 HDRAEYAKFNNERLMAK#WDTNENPIYKQATTTFKNPVY 805 |
| Caenorhabditis elegans | Query 753 YDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 +|| ||+ | |+ #| + ||+|| | || || + Sbjct 767 HDRSEYATFNNERLMAK#WDTNENPIYKQATTTFKNPVY 804 |
| Halocynthia roretzi | Query 743 VLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 ++ +++ + |+||| +|+||+ #| + ||+| +| + || | Sbjct 784 LIIWKVIQTLRDKREYEKFKKEEDLRK#WTKGENPVYVNASSKFDNPMF 831 |
| Anopheles gambiae str. PEST | Query 740 LGLVLAYRLSVEIYDRREYSRFEKEQQQLN#WKQDSNPLYKSAIT 783 | ++ || + ||+ +++||||++| # | +||||| |+ Sbjct 747 LLMLFCYRCKIMYDDRKMFAKFEKEREQET#KYQMESPLYKSPIS 790 |
| Cyprinus carpio | Query 754 DRREYSRFEKEQQQLN#WKQDSNPLYKSAITTTINPRF 790 | ||+ ||||+++ # +|||+++| || || | Sbjct 729 DLREWKRFEKDRKHEK#-TSGTNPLFQNATTTIQNPTF 764 |
[Site 5] FEKEQQQLNW770-KQDSNPLYKS
Trp770 Lys
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Phe761 | Glu762 | Lys763 | Glu764 | Gln765 | Gln766 | Gln767 | Leu768 | Asn769 | Trp770 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Lys771 | Gln772 | Asp773 | Ser774 | Asn775 | Pro776 | Leu777 | Tyr778 | Lys779 | Ser780 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| GLVLAYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADSPTL |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 128.00 | 10 | integrin, beta 7 |
| 2 | Pan troglodytes | 128.00 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 3 | N/A | 111.00 | 24 | integrin beta-7 subunit |
| 4 | Mus musculus | 111.00 | 12 | integrin beta 7 |
| 5 | Mus sp. | 111.00 | 1 | beta 7 integrin |
| 6 | Rattus norvegicus | 108.00 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 105.00 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Gallus gallus | 64.30 | 3 | integrin, beta 2 |
| 9 | Ictalurus punctatus | 61.20 | 2 | beta-1 integrin |
| 10 | Danio rerio | 59.70 | 6 | integrin, beta 1b.1 |
| 11 | Bos taurus | 58.50 | 7 | integrin beta 1 |
| 12 | Tetraodon nigroviridis | 58.50 | 6 | unnamed protein product |
| 13 | Sus scrofa | 58.50 | 3 | integrin beta-1 subunit |
| 14 | Xenopus laevis | 58.50 | 2 | integrin beta-1 subunit |
| 15 | Pongo pygmaeus | 58.50 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 16 | Oryctolagus cuniculus | 57.40 | 1 | integrin beta 1 |
| 17 | synthetic construct | 56.60 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 18 | Homo sapiens | 56.60 | 1 | integrin, beta 2 precursor |
| 19 | Felis catus | 55.80 | 1 | integrin beta 1 |
| 20 | Ovis aries | 53.50 | 2 | antigen CD18 |
| 21 | Anopheles gambiae | 53.50 | 2 | integrin beta subunit |
| 22 | Ovis canadensis | 53.50 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 23 | Anopheles gambiae str. PEST | 53.50 | 1 | integrin beta subunit (AGAP000815-PA) |
| 24 | Xenopus laevis | 53.10 | 1 | hypothetical protein LOC379708 |
| 25 | Crassostrea gigas | 53.10 | 1 | integrin beta cgh |
| 26 | Pseudoplusia includens | 52.40 | 1 | integrin beta 1 |
| 27 | Sigmodon hispidus | 51.20 | 1 | AF445415_1 integrin beta-2 precursor |
| 28 | Strongylocentrotus purpuratus | 50.80 | 3 | integrin beta L subunit |
| 29 | Gallus gallus | 50.40 | 2 | integrin, beta 3 precursor |
| 30 | Pacifastacus leniusculus | 50.40 | 1 | integrin |
| 31 | Drosophila melanogaster | 50.10 | 1 | myospheroid CG1560-PA |
| 32 | Oryctolagus cuniculus | 50.10 | 1 | glycoprotein IIIa |
| 33 | Schistosoma japonicum | 49.30 | 1 | SJCHGC06221 protein |
| 34 | rats, Peptide Partial, 723 aa | 48.50 | 1 | beta 3 integrin, GPIIIA |
| 35 | Sus scrofa | 48.50 | 1 | integrin beta chain, beta 3 |
| 36 | Mus musculus | 48.50 | 1 | integrin beta 3 precursor |
| 37 | Canis lupus familiaris | 48.50 | 1 | integrin beta chain, beta 3 |
| 38 | mice, Peptide Partial, 680 aa | 48.50 | 1 | beta 3 integrin, GPIIIA |
| 39 | Biomphalaria glabrata | 48.10 | 1 | beta integrin subunit |
| 40 | Podocoryne carnea | 47.80 | 1 | AF308652_1 integrin beta chain |
| 41 | Acropora millepora | 45.10 | 1 | integrin subunit betaCn1 |
| 42 | Lytechinus variegatus | 43.90 | 1 | beta-C integrin subunit |
| 43 | Caenorhabditis briggsae | 42.40 | 1 | Hypothetical protein CBG03601 |
| 44 | Caenorhabditis elegans | 41.20 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 45 | Halocynthia roretzi | 39.30 | 1 | integrin beta Hr2 precursor |
| 46 | Anopheles gambiae str. PEST | 38.10 | 1 | AGAP010233-PA |
| 47 | Cyprinus carpio | 36.20 | 2 | integrin beta2-chain |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||| Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEADSPTL 798 |
| Pan troglodytes | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||| Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEADSPTL 798 |
| N/A | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEAD--SPTL 798 |||||||||||||||||| |||||||||||#|||+|||||||||||+||||| + ||+| Sbjct 739 GLVLAYRLSVEIYDRREYRRFEKEQQQLNW#KQDNNPLYKSAITTTVNPRFQGTNGRSPSL 798 |
| Mus musculus | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEAD--SPTL 798 |||||||||||||||||| |||||||||||#|||+|||||||||||+||||| + ||+| Sbjct 740 GLVLAYRLSVEIYDRREYRRFEKEQQQLNW#KQDNNPLYKSAITTTVNPRFQGTNGRSPSL 799 |
| Mus sp. | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEAD--SPTL 798 |||||||||||||||||| |||||||||||#|||+|||||||||||+||||| + ||+| Sbjct 740 GLVLAYRLSVEIYDRREYRRFEKEQQQLNW#KQDNNPLYKSAITTTVNPRFQGTNGRSPSL 799 |
| Rattus norvegicus | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEADSPTL 798 |||||||||||+||| ||||||||+|||||#|||||||||||+|||+||||| + +| Sbjct 574 GLVLAYRLSVEVYDRLEYSRFEKERQQLNW#KQDSNPLYKSAVTTTVNPRFQGGNKQSL 631 |
| Canis familiaris | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEADS 795 |||||||||||||||||+|||||||+ |||#||++||||+||||||+||+||| | Sbjct 673 GLVLAYRLSVEIYDRREFSRFEKEQKHLNW#KQENNPLYRSAITTTVNPQFQETGS 727 |
| Gallus gallus | Query 751 EIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 ||+||||| |||||+ + |# + |||+||| || +|||| Sbjct 730 EIFDRREYRRFEKEKSKAKW#NEADNPLFKSATTTVMNPRF 769 |
| Ictalurus punctatus | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+ ++| + |+||||+++||||+ |# ||+||||+|| +||+++ Sbjct 755 ALLFIWKLLMIIHDRREFAKFEKEKMNAKW#DAGENPIYKSAVTTVVNPKYE 805 |
| Danio rerio | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+||||+ +||||+ |# ||+||||+|| +|||++ Sbjct 746 IHDRREFDKFEKEKNNAKW#DTGENPIYKSAVTTVVNPRYE 785 |
| Bos taurus | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ |# ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKW#DTGENPIYKSAVTTVVNPKYE 796 |
| Tetraodon nigroviridis | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ |# ||+||||+|| +||+++ Sbjct 750 IHDRREFAKFEKEKMNAKW#DTGENPIYKSAVTTVVNPKYE 789 |
| Sus scrofa | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ |# ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKW#DTGENPIYKSAVTTVVNPKYE 796 |
| Xenopus laevis | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ |# ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKW#DTGENPIYKSAVTTVVNPKYE 796 |
| Pongo pygmaeus | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ |# ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKW#DTGENPIYKSAVTTVVNPKYE 796 |
| Oryctolagus cuniculus | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+||||+++||||+ |# ||+||||+|| +||+++ Sbjct 22 IHDRREFAKFEKEKMNAKW#DTGENPIYKSAVTTVVNPKYE 61 |
| synthetic construct | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEA 793 |++ ++ + + | ||| |||||+ + |# | |||+||| || +||+| |+ Sbjct 719 LLVIWKALIHLSDLREYRRFEKEKLKSQW#NND-NPLFKSATTTVMNPKFAES 769 |
| Homo sapiens | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEA 793 |++ ++ + + | ||| |||||+ + |# | |||+||| || +||+| |+ Sbjct 719 LLVIWKALIHLSDLREYRRFEKEKLKSQW#NND-NPLFKSATTTVMNPKFAES 769 |
| Felis catus | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+| ||+++||||+ |# ||+||||+|| +||+++ Sbjct 757 IHDTREFAKFEKEKMNAKW#DTGENPIYKSAVTTVVNPKYE 796 |
| Ovis aries | Query 746 YRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+ + |# | |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEKLKSQW#NND-NPLFKSATTTVMNPKFAES 770 |
| Anopheles gambiae | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 ++| +++ |+||||++|||||+ |# ||+|| | || || + Sbjct 785 AVLLLWKVLTSIHDRREFARFEKERMMAKW#DTGENPIYKQATTTFKNPTY 834 |
| Ovis canadensis | Query 746 YRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+ + |# | |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEKLKSQW#NND-NPLFKSATTTVMNPKFAES 770 |
| Anopheles gambiae str. PEST | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 ++| +++ |+||||++|||||+ |# ||+|| | || || + Sbjct 785 AVLLLWKVLTSIHDRREFARFEKERMMAKW#DTGENPIYKQATTTFKNPTY 834 |
| Xenopus laevis | Query 743 VLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 ++ +++ || || || |||||+ |# |||| +| || || | Sbjct 722 LIIWKIITEIKDRNEYQRFEKERMNSKW#NPGHNPLYHNATTTVQNPNF 769 |
| Crassostrea gigas | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQE 792 |+| ++| | |+|| +||||| |# ||+|| | +| +|| +++ Sbjct 749 LLLIWKLFTTISDKRELARFEKEAMNARW#DTGENPIYKQATSTFVNPTYRQ 799 |
| Pseudoplusia includens | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 |++ ++++ +||||++|||||+ |# ||+|| | +| || + Sbjct 785 ALLMLWKMATTSHDRREFARFEKERMMAKW#DTGENPIYKQATSTFKNPTY 834 |
| Sigmodon hispidus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEA 793 ++ + | ||| ||||+ + |# | |||+||| || +||+| |+ Sbjct 723 WKALTHLTDLREYRHFEKEKLKSQW#NND-NPLFKSATTTVMNPKFAES 769 |
| Strongylocentrotus purpuratus | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 | |+|| + |+|||+++| + ++ |# | ||+|||+ || || + Sbjct 752 LARAWRLYTYVQDKREYAQWENDCKKAQW#DQSDNPIYKSSTTTFKNPTY 800 |
| Gallus gallus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 ++| + |+||||++|||+|+ + |# +||||| | +| | ++ Sbjct 733 WKLLITIHDRREFARFEEEKARAKW#DTGNNPLYKEATSTFTNITYR 778 |
| Pacifastacus leniusculus | Query 753 YDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQEA 793 +|||||++||||++ + #|+ ||||||| || || | ++ Sbjct 760 HDRREYAKFEKERKLPSG#KRAENPLYKSAKTTFQNPAFAQS 800 |
| Drosophila melanogaster | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 |+||||++|||||+ |# ||+|| | +| || + Sbjct 805 IHDRREFARFEKERMNAKW#DTGENPIYKQATSTFKNPMY 843 |
| Oryctolagus cuniculus | Query 741 GLVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 |+| ++| + |+||+|+++||+|+ + |# +||||| | +| | ++ Sbjct 736 ALLLIWKLLITIHDRKEFAKFEEERARAKW#DTANNPLYKEATSTFTNITYR 786 |
| Schistosoma japonicum | Query 746 YRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQE 792 |+| + | |||| + |+++ + + |#+ ||+++| | +|| |+| Sbjct 239 YKLVITIDDRRELANFKQQGENMRW#EMAENPIFESPTTNVLNPTFEE 285 |
| rats, Peptide Partial, 723 aa | Query 743 VLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 +| ++| + |+||+|+++||+|+ + |# +||||| | +| | ++ Sbjct 673 LLIWKLLITIHDRKEFAKFEEERARAKW#DTANNPLYKEATSTFTNITYR 721 |
| Sus scrofa | Query 743 VLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 +| ++| + |+||+|+++||+|+ + |# +||||| | +| | ++ Sbjct 734 LLIWKLLITIHDRKEFAKFEEERARAKW#DTANNPLYKEATSTFTNITYR 782 |
| Mus musculus | Query 743 VLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 +| ++| + |+||+|+++||+|+ + |# +||||| | +| | ++ Sbjct 737 LLIWKLLITIHDRKEFAKFEEERARAKW#DTANNPLYKEATSTFTNITYR 785 |
| Canis lupus familiaris | Query 743 VLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRFQ 791 +| ++| + |+||+|+++||+|+ + |# +||||| | +| | ++ Sbjct 734 LLIWKLLITIHDRKEFAKFEEERARAKW#DTANNPLYKEATSTFTNITYR 782 |
| mice, Peptide Partial, 680 aa | Query 743 VLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTIN 787 +| ++| + |+||+|+++||+|+ + |# +||||| | +| | Sbjct 634 LLIWKLLITIHDRKEFAKFEEERARAKW#DTANNPLYKEATSTFTN 678 |
| Biomphalaria glabrata | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 |+| ||+++||||+| |# ||+|| | +| || + Sbjct 747 IHDTREFAKFEKERQNAKW#DTGENPIYKQATSTFKNPTY 785 |
| Podocoryne carnea | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 | ||||+++|||++| |# ||+|| | +| || + Sbjct 740 IQDRREFAKFEKDRQNPKW#DSGENPIYKKATSTFQNPMY 778 |
| Acropora millepora | Query 754 DRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 || || +||+|+ |# ++ ||||++| || || + Sbjct 751 DRIEYQKFERERMHSKW#TREKNPLYQAAKTTFENPTY 787 |
| Lytechinus variegatus | Query 752 IYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 |+||||+ ||||+ |#+ ||+|| + + || + Sbjct 765 IHDRREFQNFEKERANATW#EGGENPIYKPSTSVFKNPTY 803 |
| Caenorhabditis briggsae | Query 753 YDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 +|| ||++| |+ |# + ||+|| | || || + Sbjct 768 HDRAEYAKFNNERLMAKW#DTNENPIYKQATTTFKNPVY 805 |
| Caenorhabditis elegans | Query 753 YDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 +|| ||+ | |+ |# + ||+|| | || || + Sbjct 767 HDRSEYATFNNERLMAKW#DTNENPIYKQATTTFKNPVY 804 |
| Halocynthia roretzi | Query 743 VLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 ++ +++ + |+||| +|+||+ |# + ||+| +| + || | Sbjct 784 LIIWKVIQTLRDKREYEKFKKEEDLRKW#TKGENPVYVNASSKFDNPMF 831 |
| Anopheles gambiae str. PEST | Query 742 LVLAYRLSVEIYDRREYSRFEKEQQQLNW#KQDSNPLYKSAIT 783 ++ || + ||+ +++||||++| # | +||||| |+ Sbjct 749 MLFCYRCKIMYDDRKMFAKFEKEREQETK#YQMESPLYKSPIS 790 |
| Cyprinus carpio | Query 754 DRREYSRFEKEQQQLNW#KQDSNPLYKSAITTTINPRF 790 | ||+ ||||+++ # +|||+++| || || | Sbjct 729 DLREWKRFEKDRKHEK-#TSGTNPLFQNATTTIQNPTF 764 |
[Site 6] EQQQLNWKQD773-SNPLYKSAIT
Asp773 Ser
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu764 | Gln765 | Gln766 | Gln767 | Leu768 | Asn769 | Trp770 | Lys771 | Gln772 | Asp773 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser774 | Asn775 | Pro776 | Leu777 | Tyr778 | Lys779 | Ser780 | Ala781 | Ile782 | Thr783 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LAYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADSPTL |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 122.00 | 10 | integrin, beta 7 |
| 2 | Pan troglodytes | 122.00 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 3 | N/A | 106.00 | 24 | integrin beta-7 subunit |
| 4 | Mus musculus | 106.00 | 12 | integrin beta 7 |
| 5 | Mus sp. | 106.00 | 1 | beta 7 integrin |
| 6 | Rattus norvegicus | 102.00 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 99.80 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Gallus gallus | 64.30 | 3 | integrin, beta 2 |
| 9 | Danio rerio | 59.70 | 6 | integrin, beta 1b.1 |
| 10 | Ictalurus punctatus | 59.70 | 2 | beta-1 integrin |
| 11 | Bos taurus | 58.50 | 7 | integrin beta 1 |
| 12 | Tetraodon nigroviridis | 58.50 | 5 | unnamed protein product |
| 13 | Sus scrofa | 58.50 | 3 | integrin beta-1 subunit |
| 14 | Xenopus laevis | 58.50 | 2 | integrin beta-1 subunit |
| 15 | Pongo pygmaeus | 58.50 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 16 | Oryctolagus cuniculus | 57.40 | 1 | integrin beta 1 |
| 17 | Felis catus | 55.80 | 1 | integrin beta 1 |
| 18 | synthetic construct | 54.70 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 19 | Homo sapiens | 54.70 | 1 | integrin, beta 2 precursor |
| 20 | Ovis aries | 53.50 | 2 | antigen CD18 |
| 21 | Ovis canadensis | 53.50 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 22 | Xenopus laevis | 52.80 | 1 | hypothetical protein LOC379708 |
| 23 | Anopheles gambiae | 52.40 | 2 | integrin beta subunit |
| 24 | Anopheles gambiae str. PEST | 52.40 | 1 | integrin beta subunit (AGAP000815-PA) |
| 25 | Crassostrea gigas | 51.20 | 1 | integrin beta cgh |
| 26 | Sigmodon hispidus | 51.20 | 1 | AF445415_1 integrin beta-2 precursor |
| 27 | Strongylocentrotus purpuratus | 50.40 | 3 | integrin beta L subunit |
| 28 | Gallus gallus | 50.40 | 2 | integrin, beta 3 precursor |
| 29 | Pseudoplusia includens | 50.40 | 1 | integrin beta 1 |
| 30 | Pacifastacus leniusculus | 50.10 | 1 | integrin |
| 31 | Drosophila melanogaster | 49.70 | 1 | myospheroid CG1560-PA |
| 32 | Schistosoma japonicum | 48.50 | 1 | SJCHGC06221 protein |
| 33 | mice, Peptide Partial, 680 aa | 48.10 | 1 | beta 3 integrin, GPIIIA |
| 34 | Canis lupus familiaris | 48.10 | 1 | integrin beta chain, beta 3 |
| 35 | rats, Peptide Partial, 723 aa | 47.80 | 1 | beta 3 integrin, GPIIIA |
| 36 | Biomphalaria glabrata | 47.80 | 1 | beta integrin subunit |
| 37 | Mus musculus | 47.80 | 1 | integrin beta 3 precursor |
| 38 | Podocoryne carnea | 47.80 | 1 | AF308652_1 integrin beta chain |
| 39 | Oryctolagus cuniculus | 47.80 | 1 | glycoprotein IIIa |
| 40 | Sus scrofa | 47.80 | 1 | integrin beta chain, beta 3 |
| 41 | Acropora millepora | 44.70 | 1 | integrin subunit betaCn1 |
| 42 | Lytechinus variegatus | 43.90 | 1 | beta-C integrin subunit |
| 43 | Caenorhabditis briggsae | 42.00 | 1 | Hypothetical protein CBG03601 |
| 44 | Caenorhabditis elegans | 40.80 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 45 | Halocynthia roretzi | 38.90 | 2 | integrin beta Hr2 precursor |
| 46 | Anopheles gambiae str. PEST | 36.60 | 1 | AGAP010233-PA |
| 47 | Cyprinus carpio | 36.20 | 2 | integrin beta2-chain |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||| Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEADSPTL 798 |
| Pan troglodytes | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||| Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEADSPTL 798 |
| N/A | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEAD--SPTL 798 ||||||||||||||| ||||||||||||||#+|||||||||||+||||| + ||+| Sbjct 742 LAYRLSVEIYDRREYRRFEKEQQQLNWKQD#NNPLYKSAITTTVNPRFQGTNGRSPSL 798 |
| Mus musculus | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEAD--SPTL 798 ||||||||||||||| ||||||||||||||#+|||||||||||+||||| + ||+| Sbjct 743 LAYRLSVEIYDRREYRRFEKEQQQLNWKQD#NNPLYKSAITTTVNPRFQGTNGRSPSL 799 |
| Mus sp. | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEAD--SPTL 798 ||||||||||||||| ||||||||||||||#+|||||||||||+||||| + ||+| Sbjct 743 LAYRLSVEIYDRREYRRFEKEQQQLNWKQD#NNPLYKSAITTTVNPRFQGTNGRSPSL 799 |
| Rattus norvegicus | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEADSPTL 798 ||||||||+||| ||||||||+||||||||#||||||||+|||+||||| + +| Sbjct 577 LAYRLSVEVYDRLEYSRFEKERQQLNWKQD#SNPLYKSAVTTTVNPRFQGGNKQSL 631 |
| Canis familiaris | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEADS 795 ||||||||||||||+|||||||+ |||||+#+||||+||||||+||+||| | Sbjct 676 LAYRLSVEIYDRREFSRFEKEQKHLNWKQE#NNPLYRSAITTTVNPQFQETGS 727 |
| Gallus gallus | Query 751 EIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 ||+||||| |||||+ + | + # |||+||| || +|||| Sbjct 730 EIFDRREYRRFEKEKSKAKWNEA#DNPLFKSATTTVMNPRF 769 |
| Danio rerio | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 |+||||+ +||||+ | # ||+||||+|| +|||++ Sbjct 746 IHDRREFDKFEKEKNNAKWDTG#ENPIYKSAVTTVVNPRYE 785 |
| Ictalurus punctatus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 ++| + |+||||+++||||+ | # ||+||||+|| +||+++ Sbjct 760 WKLLMIIHDRREFAKFEKEKMNAKWDAG#ENPIYKSAVTTVVNPKYE 805 |
| Bos taurus | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 |+||||+++||||+ | # ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYE 796 |
| Tetraodon nigroviridis | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 |+||||+++||||+ | # ||+||||+|| +||+++ Sbjct 750 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYE 789 |
| Sus scrofa | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 |+||||+++||||+ | # ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYE 796 |
| Xenopus laevis | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 |+||||+++||||+ | # ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYE 796 |
| Pongo pygmaeus | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 |+||||+++||||+ | # ||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYE 796 |
| Oryctolagus cuniculus | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 |+||||+++||||+ | # ||+||||+|| +||+++ Sbjct 22 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYE 61 |
| Felis catus | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 |+| ||+++||||+ | # ||+||||+|| +||+++ Sbjct 757 IHDTREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYE 796 |
| synthetic construct | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEA 793 ++ + + | ||| |||||+ + | |# |||+||| || +||+| |+ Sbjct 723 WKALIHLSDLREYRRFEKEKLKSQWNND#-NPLFKSATTTVMNPKFAES 769 |
| Homo sapiens | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEA 793 ++ + + | ||| |||||+ + | |# |||+||| || +||+| |+ Sbjct 723 WKALIHLSDLREYRRFEKEKLKSQWNND#-NPLFKSATTTVMNPKFAES 769 |
| Ovis aries | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+ + | |# |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEKLKSQWNND#-NPLFKSATTTVMNPKFAES 770 |
| Ovis canadensis | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+ + | |# |||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEKLKSQWNND#-NPLFKSATTTVMNPKFAES 770 |
| Xenopus laevis | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 + +++ || || || |||||+ | # |||| +| || || | Sbjct 723 IIWKIITEIKDRNEYQRFEKERMNSKWNPG#HNPLYHNATTTVQNPNF 769 |
| Anopheles gambiae | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 | +++ |+||||++|||||+ | # ||+|| | || || + Sbjct 788 LLWKVLTSIHDRREFARFEKERMMAKWDTG#ENPIYKQATTTFKNPTY 834 |
| Anopheles gambiae str. PEST | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 | +++ |+||||++|||||+ | # ||+|| | || || + Sbjct 788 LLWKVLTSIHDRREFARFEKERMMAKWDTG#ENPIYKQATTTFKNPTY 834 |
| Crassostrea gigas | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQE 792 | ++| | |+|| +||||| | # ||+|| | +| +|| +++ Sbjct 751 LIWKLFTTISDKRELARFEKEAMNARWDTG#ENPIYKQATSTFVNPTYRQ 799 |
| Sigmodon hispidus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEA 793 ++ + | ||| ||||+ + | |# |||+||| || +||+| |+ Sbjct 723 WKALTHLTDLREYRHFEKEKLKSQWNND#-NPLFKSATTTVMNPKFAES 769 |
| Strongylocentrotus purpuratus | Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 |+|| + |+|||+++| + ++ | | # ||+|||+ || || + Sbjct 755 AWRLYTYVQDKREYAQWENDCKKAQWDQS#DNPIYKSSTTTFKNPTY 800 |
| Gallus gallus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 ++| + |+||||++|||+|+ + | #+||||| | +| | ++ Sbjct 733 WKLLITIHDRREFARFEEEKARAKWDTG#NNPLYKEATSTFTNITYR 778 |
| Pseudoplusia includens | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 + ++++ +||||++|||||+ | # ||+|| | +| || + Sbjct 788 MLWKMATTSHDRREFARFEKERMMAKWDTG#ENPIYKQATSTFKNPTY 834 |
| Pacifastacus leniusculus | Query 753 YDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQEA 793 +|||||++||||++ + |+ # ||||||| || || | ++ Sbjct 760 HDRREYAKFEKERKLPSGKRA#ENPLYKSAKTTFQNPAFAQS 800 |
| Drosophila melanogaster | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 |+||||++|||||+ | # ||+|| | +| || + Sbjct 805 IHDRREFARFEKERMNAKWDTG#ENPIYKQATSTFKNPMY 843 |
| Schistosoma japonicum | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQE 792 |+| + | |||| + |+++ + + |+ # ||+++| | +|| |+| Sbjct 239 YKLVITIDDRRELANFKQQGENMRWEMA#ENPIFESPTTNVLNPTFEE 285 |
| mice, Peptide Partial, 680 aa | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTIN 787 | ++| + |+||+|+++||+|+ + | #+||||| | +| | Sbjct 635 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTN 678 |
| Canis lupus familiaris | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 | ++| + |+||+|+++||+|+ + | #+||||| | +| | ++ Sbjct 735 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYR 782 |
| rats, Peptide Partial, 723 aa | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 | ++| + |+||+|+++||+|+ + | #+||||| | +| | ++ Sbjct 674 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYR 721 |
| Biomphalaria glabrata | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 |+| ||+++||||+| | # ||+|| | +| || + Sbjct 747 IHDTREFAKFEKERQNAKWDTG#ENPIYKQATSTFKNPTY 785 |
| Mus musculus | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 | ++| + |+||+|+++||+|+ + | #+||||| | +| | ++ Sbjct 738 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYR 785 |
| Podocoryne carnea | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 | ||||+++|||++| | # ||+|| | +| || + Sbjct 740 IQDRREFAKFEKDRQNPKWDSG#ENPIYKKATSTFQNPMY 778 |
| Oryctolagus cuniculus | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 | ++| + |+||+|+++||+|+ + | #+||||| | +| | ++ Sbjct 739 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYR 786 |
| Sus scrofa | Query 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 | ++| + |+||+|+++||+|+ + | #+||||| | +| | ++ Sbjct 735 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYR 782 |
| Acropora millepora | Query 754 DRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 || || +||+|+ | ++# ||||++| || || + Sbjct 751 DRIEYQKFERERMHSKWTRE#KNPLYQAAKTTFENPTY 787 |
| Lytechinus variegatus | Query 752 IYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 |+||||+ ||||+ |+ # ||+|| + + || + Sbjct 765 IHDRREFQNFEKERANATWEGG#ENPIYKPSTSVFKNPTY 803 |
| Caenorhabditis briggsae | Query 753 YDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 +|| ||++| |+ | +# ||+|| | || || + Sbjct 768 HDRAEYAKFNNERLMAKWDTN#ENPIYKQATTTFKNPVY 805 |
| Caenorhabditis elegans | Query 753 YDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 +|| ||+ | |+ | +# ||+|| | || || + Sbjct 767 HDRSEYATFNNERLMAKWDTN#ENPIYKQATTTFKNPVY 804 |
| Halocynthia roretzi | Query 754 DRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 |+||| +|+||+ | + # ||+| +| + || | Sbjct 795 DKREYEKFKKEEDLRKWTKG#ENPVYVNASSKFDNPMF 831 |
| Anopheles gambiae str. PEST | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAIT 783 || + ||+ +++||||++| | # +||||| |+ Sbjct 753 YRCKIMYDDRKMFAKFEKEREQETKYQM#ESPLYKSPIS 790 |
| Cyprinus carpio | Query 754 DRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRF 790 | ||+ ||||+++ #+|||+++| || || | Sbjct 729 DLREWKRFEKDRKHEK-TSG#TNPLFQNATTTIQNPTF 764 |
[Site 7] QQQLNWKQDS774-NPLYKSAITT
Ser774 Asn
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gln765 | Gln766 | Gln767 | Leu768 | Asn769 | Trp770 | Lys771 | Gln772 | Asp773 | Ser774 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Asn775 | Pro776 | Leu777 | Tyr778 | Lys779 | Ser780 | Ala781 | Ile782 | Thr783 | Thr784 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| AYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADSPTL |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 121.00 | 10 | integrin, beta 7 |
| 2 | Pan troglodytes | 121.00 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 3 | N/A | 104.00 | 24 | integrin beta-7 subunit |
| 4 | Mus musculus | 104.00 | 12 | integrin beta 7 |
| 5 | Mus sp. | 104.00 | 1 | beta 7 integrin |
| 6 | Rattus norvegicus | 101.00 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 98.20 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Gallus gallus | 63.90 | 3 | integrin, beta 2 |
| 9 | Danio rerio | 59.70 | 6 | integrin, beta 1b.1 |
| 10 | Ictalurus punctatus | 59.70 | 2 | beta-1 integrin |
| 11 | Bos taurus | 58.50 | 7 | integrin beta 1 |
| 12 | Tetraodon nigroviridis | 58.50 | 5 | unnamed protein product |
| 13 | Sus scrofa | 58.50 | 3 | integrin beta-1 subunit |
| 14 | Xenopus laevis | 58.50 | 2 | integrin beta-1 subunit |
| 15 | Pongo pygmaeus | 58.20 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 16 | Oryctolagus cuniculus | 57.40 | 1 | integrin beta 1 |
| 17 | Felis catus | 55.80 | 1 | integrin beta 1 |
| 18 | synthetic construct | 54.70 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 19 | Homo sapiens | 54.70 | 1 | integrin, beta 2 precursor |
| 20 | Ovis aries | 53.50 | 2 | antigen CD18 |
| 21 | Ovis canadensis | 53.10 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 22 | Xenopus laevis | 52.80 | 1 | hypothetical protein LOC379708 |
| 23 | Anopheles gambiae | 51.20 | 2 | integrin beta subunit |
| 24 | Sigmodon hispidus | 50.80 | 1 | AF445415_1 integrin beta-2 precursor |
| 25 | Anopheles gambiae str. PEST | 50.80 | 1 | integrin beta subunit (AGAP000815-PA) |
| 26 | Strongylocentrotus purpuratus | 50.40 | 3 | integrin beta L subunit |
| 27 | Gallus gallus | 50.40 | 2 | integrin, beta 3 precursor |
| 28 | Pseudoplusia includens | 50.10 | 1 | integrin beta 1 |
| 29 | Pacifastacus leniusculus | 49.70 | 1 | integrin |
| 30 | Crassostrea gigas | 49.70 | 1 | integrin beta cgh |
| 31 | Drosophila melanogaster | 49.30 | 1 | myospheroid CG1560-PA |
| 32 | Schistosoma japonicum | 48.10 | 1 | SJCHGC06221 protein |
| 33 | Podocoryne carnea | 47.40 | 1 | AF308652_1 integrin beta chain |
| 34 | Biomphalaria glabrata | 47.40 | 1 | beta integrin subunit |
| 35 | mice, Peptide Partial, 680 aa | 47.00 | 1 | beta 3 integrin, GPIIIA |
| 36 | Canis lupus familiaris | 47.00 | 1 | integrin beta chain, beta 3 |
| 37 | rats, Peptide Partial, 723 aa | 46.60 | 1 | beta 3 integrin, GPIIIA |
| 38 | Mus musculus | 46.60 | 1 | integrin beta 3 precursor |
| 39 | Oryctolagus cuniculus | 46.60 | 1 | glycoprotein IIIa |
| 40 | Sus scrofa | 46.60 | 1 | integrin beta chain, beta 3 |
| 41 | Acropora millepora | 44.30 | 1 | integrin subunit betaCn1 |
| 42 | Lytechinus variegatus | 43.90 | 1 | beta-C integrin subunit |
| 43 | Caenorhabditis briggsae | 41.60 | 1 | Hypothetical protein CBG03601 |
| 44 | Caenorhabditis elegans | 40.80 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 45 | Halocynthia roretzi | 38.50 | 2 | integrin beta Hr2 precursor |
| 46 | Cyprinus carpio | 36.20 | 2 | integrin beta2-chain |
| 47 | Anopheles gambiae str. PEST | 36.20 | 1 | AGAP010233-PA |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||| Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEADSPTL 798 |
| Pan troglodytes | Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||| Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEADSPTL 798 |
| N/A | Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEAD--SPTL 798 |||||||||||||| ||||||||||||||+#|||||||||||+||||| + ||+| Sbjct 743 AYRLSVEIYDRREYRRFEKEQQQLNWKQDN#NPLYKSAITTTVNPRFQGTNGRSPSL 798 |
| Mus musculus | Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEAD--SPTL 798 |||||||||||||| ||||||||||||||+#|||||||||||+||||| + ||+| Sbjct 744 AYRLSVEIYDRREYRRFEKEQQQLNWKQDN#NPLYKSAITTTVNPRFQGTNGRSPSL 799 |
| Mus sp. | Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEAD--SPTL 798 |||||||||||||| ||||||||||||||+#|||||||||||+||||| + ||+| Sbjct 744 AYRLSVEIYDRREYRRFEKEQQQLNWKQDN#NPLYKSAITTTVNPRFQGTNGRSPSL 799 |
| Rattus norvegicus | Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEADSPTL 798 |||||||+||| ||||||||+|||||||||#|||||||+|||+||||| + +| Sbjct 578 AYRLSVEVYDRLEYSRFEKERQQLNWKQDS#NPLYKSAVTTTVNPRFQGGNKQSL 631 |
| Canis familiaris | Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEADS 795 |||||||||||||+|||||||+ |||||++#||||+||||||+||+||| | Sbjct 677 AYRLSVEIYDRREFSRFEKEQKHLNWKQEN#NPLYRSAITTTVNPQFQETGS 727 |
| Gallus gallus | Query 751 EIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 ||+||||| |||||+ + | + #|||+||| || +|||| Sbjct 730 EIFDRREYRRFEKEKSKAKWNEAD#NPLFKSATTTVMNPRF 769 |
| Danio rerio | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 |+||||+ +||||+ | #||+||||+|| +|||++ Sbjct 746 IHDRREFDKFEKEKNNAKWDTGE#NPIYKSAVTTVVNPRYE 785 |
| Ictalurus punctatus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 ++| + |+||||+++||||+ | #||+||||+|| +||+++ Sbjct 760 WKLLMIIHDRREFAKFEKEKMNAKWDAGE#NPIYKSAVTTVVNPKYE 805 |
| Bos taurus | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 |+||||+++||||+ | #||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTGE#NPIYKSAVTTVVNPKYE 796 |
| Tetraodon nigroviridis | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 |+||||+++||||+ | #||+||||+|| +||+++ Sbjct 750 IHDRREFAKFEKEKMNAKWDTGE#NPIYKSAVTTVVNPKYE 789 |
| Sus scrofa | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 |+||||+++||||+ | #||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTGE#NPIYKSAVTTVVNPKYE 796 |
| Xenopus laevis | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 |+||||+++||||+ | #||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTGE#NPIYKSAVTTVVNPKYE 796 |
| Pongo pygmaeus | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 |+||||+++||||+ | #||+||||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTGE#NPIYKSAVTTVVNPKYE 796 |
| Oryctolagus cuniculus | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 |+||||+++||||+ | #||+||||+|| +||+++ Sbjct 22 IHDRREFAKFEKEKMNAKWDTGE#NPIYKSAVTTVVNPKYE 61 |
| Felis catus | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 |+| ||+++||||+ | #||+||||+|| +||+++ Sbjct 757 IHDTREFAKFEKEKMNAKWDTGE#NPIYKSAVTTVVNPKYE 796 |
| synthetic construct | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEA 793 ++ + + | ||| |||||+ + | | #|||+||| || +||+| |+ Sbjct 723 WKALIHLSDLREYRRFEKEKLKSQWNND-#NPLFKSATTTVMNPKFAES 769 |
| Homo sapiens | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEA 793 ++ + + | ||| |||||+ + | | #|||+||| || +||+| |+ Sbjct 723 WKALIHLSDLREYRRFEKEKLKSQWNND-#NPLFKSATTTVMNPKFAES 769 |
| Ovis aries | Query 754 DRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEA 793 | ||| |||||+ + | | #|||+||| || +||+| |+ Sbjct 732 DLREYHRFEKEKLKSQWNND-#NPLFKSATTTVMNPKFAES 770 |
| Ovis canadensis | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEA 793 ++ + | ||| |||||+ + | | #|||+||| || +||+| |+ Sbjct 724 WKALTHLSDLREYHRFEKEKLKSQWNND-#NPLFKSATTTVMNPKFAES 770 |
| Xenopus laevis | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 +++ || || || |||||+ | #|||| +| || || | Sbjct 725 WKIITEIKDRNEYQRFEKERMNSKWNPGH#NPLYHNATTTVQNPNF 769 |
| Anopheles gambiae | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 +++ |+||||++|||||+ | #||+|| | || || + Sbjct 790 WKVLTSIHDRREFARFEKERMMAKWDTGE#NPIYKQATTTFKNPTY 834 |
| Sigmodon hispidus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEA 793 ++ + | ||| ||||+ + | | #|||+||| || +||+| |+ Sbjct 723 WKALTHLTDLREYRHFEKEKLKSQWNND-#NPLFKSATTTVMNPKFAES 769 |
| Anopheles gambiae str. PEST | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 +++ |+||||++|||||+ | #||+|| | || || + Sbjct 790 WKVLTSIHDRREFARFEKERMMAKWDTGE#NPIYKQATTTFKNPTY 834 |
| Strongylocentrotus purpuratus | Query 745 AYRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 |+|| + |+|||+++| + ++ | | #||+|||+ || || + Sbjct 755 AWRLYTYVQDKREYAQWENDCKKAQWDQSD#NPIYKSSTTTFKNPTY 800 |
| Gallus gallus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 ++| + |+||||++|||+|+ + | +#||||| | +| | ++ Sbjct 733 WKLLITIHDRREFARFEEEKARAKWDTGN#NPLYKEATSTFTNITYR 778 |
| Pseudoplusia includens | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 ++++ +||||++|||||+ | #||+|| | +| || + Sbjct 790 WKMATTSHDRREFARFEKERMMAKWDTGE#NPIYKQATSTFKNPTY 834 |
| Pacifastacus leniusculus | Query 753 YDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQEA 793 +|||||++||||++ + |+ #||||||| || || | ++ Sbjct 760 HDRREYAKFEKERKLPSGKRAE#NPLYKSAKTTFQNPAFAQS 800 |
| Crassostrea gigas | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQE 792 ++| | |+|| +||||| | #||+|| | +| +|| +++ Sbjct 753 WKLFTTISDKRELARFEKEAMNARWDTGE#NPIYKQATSTFVNPTYRQ 799 |
| Drosophila melanogaster | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 |+||||++|||||+ | #||+|| | +| || + Sbjct 805 IHDRREFARFEKERMNAKWDTGE#NPIYKQATSTFKNPMY 843 |
| Schistosoma japonicum | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQE 792 |+| + | |||| + |+++ + + |+ #||+++| | +|| |+| Sbjct 239 YKLVITIDDRRELANFKQQGENMRWEMAE#NPIFESPTTNVLNPTFEE 285 |
| Podocoryne carnea | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 | ||||+++|||++| | #||+|| | +| || + Sbjct 740 IQDRREFAKFEKDRQNPKWDSGE#NPIYKKATSTFQNPMY 778 |
| Biomphalaria glabrata | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 |+| ||+++||||+| | #||+|| | +| || + Sbjct 747 IHDTREFAKFEKERQNAKWDTGE#NPIYKQATSTFKNPTY 785 |
| mice, Peptide Partial, 680 aa | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTIN 787 ++| + |+||+|+++||+|+ + | +#||||| | +| | Sbjct 637 WKLLITIHDRKEFAKFEEERARAKWDTAN#NPLYKEATSTFTN 678 |
| Canis lupus familiaris | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 ++| + |+||+|+++||+|+ + | +#||||| | +| | ++ Sbjct 737 WKLLITIHDRKEFAKFEEERARAKWDTAN#NPLYKEATSTFTNITYR 782 |
| rats, Peptide Partial, 723 aa | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 ++| + |+||+|+++||+|+ + | +#||||| | +| | ++ Sbjct 676 WKLLITIHDRKEFAKFEEERARAKWDTAN#NPLYKEATSTFTNITYR 721 |
| Mus musculus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 ++| + |+||+|+++||+|+ + | +#||||| | +| | ++ Sbjct 740 WKLLITIHDRKEFAKFEEERARAKWDTAN#NPLYKEATSTFTNITYR 785 |
| Oryctolagus cuniculus | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 ++| + |+||+|+++||+|+ + | +#||||| | +| | ++ Sbjct 741 WKLLITIHDRKEFAKFEEERARAKWDTAN#NPLYKEATSTFTNITYR 786 |
| Sus scrofa | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRFQ 791 ++| + |+||+|+++||+|+ + | +#||||| | +| | ++ Sbjct 737 WKLLITIHDRKEFAKFEEERARAKWDTAN#NPLYKEATSTFTNITYR 782 |
| Acropora millepora | Query 754 DRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 || || +||+|+ | ++ #||||++| || || + Sbjct 751 DRIEYQKFERERMHSKWTREK#NPLYQAAKTTFENPTY 787 |
| Lytechinus variegatus | Query 752 IYDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 |+||||+ ||||+ |+ #||+|| + + || + Sbjct 765 IHDRREFQNFEKERANATWEGGE#NPIYKPSTSVFKNPTY 803 |
| Caenorhabditis briggsae | Query 753 YDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 +|| ||++| |+ | + #||+|| | || || + Sbjct 768 HDRAEYAKFNNERLMAKWDTNE#NPIYKQATTTFKNPVY 805 |
| Caenorhabditis elegans | Query 753 YDRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 +|| ||+ | |+ | + #||+|| | || || + Sbjct 767 HDRSEYATFNNERLMAKWDTNE#NPIYKQATTTFKNPVY 804 |
| Halocynthia roretzi | Query 754 DRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 |+||| +|+||+ | + #||+| +| + || | Sbjct 795 DKREYEKFKKEEDLRKWTKGE#NPVYVNASSKFDNPMF 831 |
| Cyprinus carpio | Query 754 DRREYSRFEKEQQQLNWKQDS#NPLYKSAITTTINPRF 790 | ||+ ||||+++ +#|||+++| || || | Sbjct 729 DLREWKRFEKDRKHEK-TSGT#NPLFQNATTTIQNPTF 764 |
| Anopheles gambiae str. PEST | Query 746 YRLSVEIYDRREYSRFEKEQQQLNWKQDS#NPLYKSAIT 783 || + ||+ +++||||++| | #+||||| |+ Sbjct 753 YRCKIMYDDRKMFAKFEKEREQETKYQME#SPLYKSPIS 790 |
[Site 8] NWKQDSNPLY778-KSAITTTINP
Tyr778 Lys
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Asn769 | Trp770 | Lys771 | Gln772 | Asp773 | Ser774 | Asn775 | Pro776 | Leu777 | Tyr778 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Lys779 | Ser780 | Ala781 | Ile782 | Thr783 | Thr784 | Thr785 | Ile786 | Asn787 | Pro788 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| SVEIYDRREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADSPTL |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 112.00 | 10 | integrin, beta 7 |
| 2 | Pan troglodytes | 112.00 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 3 | N/A | 96.30 | 25 | integrin beta-7 subunit |
| 4 | Mus musculus | 96.30 | 12 | integrin beta 7 |
| 5 | Mus sp. | 96.30 | 1 | beta 7 integrin |
| 6 | Rattus norvegicus | 93.20 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 89.70 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Gallus gallus | 62.80 | 3 | integrin, beta 2 |
| 9 | Danio rerio | 59.30 | 6 | integrin, beta 1b.1 |
| 10 | Ictalurus punctatus | 58.20 | 2 | beta-1 integrin |
| 11 | Bos taurus | 57.80 | 7 | integrin beta 1 |
| 12 | Tetraodon nigroviridis | 57.80 | 5 | unnamed protein product |
| 13 | Sus scrofa | 57.80 | 3 | integrin beta-1 subunit |
| 14 | Xenopus laevis | 57.80 | 2 | integrin beta-1 subunit |
| 15 | Pongo pygmaeus | 57.00 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 16 | Oryctolagus cuniculus | 57.00 | 1 | integrin beta 1 |
| 17 | Felis catus | 55.10 | 1 | integrin beta 1 |
| 18 | synthetic construct | 54.70 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 19 | Homo sapiens | 54.70 | 1 | integrin, beta 2 precursor |
| 20 | Ovis aries | 52.80 | 2 | antigen CD18 |
| 21 | Ovis canadensis | 52.80 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 22 | Xenopus laevis | 50.40 | 1 | hypothetical protein LOC379708 |
| 23 | Sigmodon hispidus | 50.10 | 1 | AF445415_1 integrin beta-2 precursor |
| 24 | Anopheles gambiae | 49.70 | 1 | integrin beta subunit |
| 25 | Anopheles gambiae str. PEST | 49.30 | 1 | integrin beta subunit (AGAP000815-PA) |
| 26 | Pacifastacus leniusculus | 48.90 | 1 | integrin |
| 27 | Drosophila melanogaster | 48.50 | 1 | myospheroid CG1560-PA |
| 28 | Pseudoplusia includens | 48.10 | 1 | integrin beta 1 |
| 29 | Gallus gallus | 47.40 | 2 | integrin, beta 3 precursor |
| 30 | Crassostrea gigas | 47.00 | 1 | integrin beta cgh |
| 31 | Podocoryne carnea | 46.60 | 1 | AF308652_1 integrin beta chain |
| 32 | Biomphalaria glabrata | 46.60 | 1 | beta integrin subunit |
| 33 | Strongylocentrotus purpuratus | 45.80 | 3 | integrin beta G subunit |
| 34 | Canis lupus familiaris | 44.30 | 1 | integrin beta chain, beta 3 |
| 35 | Sus scrofa | 43.90 | 1 | integrin beta chain, beta 3 |
| 36 | rats, Peptide Partial, 723 aa | 43.90 | 1 | beta 3 integrin, GPIIIA |
| 37 | Oryctolagus cuniculus | 43.90 | 1 | glycoprotein IIIa |
| 38 | Acropora millepora | 43.90 | 1 | integrin subunit betaCn1 |
| 39 | mice, Peptide Partial, 680 aa | 43.90 | 1 | beta 3 integrin, GPIIIA |
| 40 | Mus musculus | 43.50 | 1 | integrin beta 3 precursor |
| 41 | Lytechinus variegatus | 43.10 | 1 | beta-C integrin subunit |
| 42 | Schistosoma japonicum | 43.10 | 1 | SJCHGC06221 protein |
| 43 | Caenorhabditis briggsae | 41.20 | 1 | Hypothetical protein CBG03601 |
| 44 | Caenorhabditis elegans | 40.00 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 45 | Halocynthia roretzi | 38.10 | 2 | integrin beta Hr2 precursor |
| 46 | Cyprinus carpio | 35.80 | 2 | integrin beta2-chain |
| 47 | Geodia cydonium | 33.90 | 1 | integrin beta subunit |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 749 SVEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 SVEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEADSPTL 798 |
| Pan troglodytes | Query 749 SVEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 SVEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEADSPTL 798 |
| N/A | Query 749 SVEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEAD--SPTL 798 |||||||||| ||||||||||||||+||||#|||||||+||||| + ||+| Sbjct 747 SVEIYDRREYRRFEKEQQQLNWKQDNNPLY#KSAITTTVNPRFQGTNGRSPSL 798 |
| Mus musculus | Query 749 SVEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEAD--SPTL 798 |||||||||| ||||||||||||||+||||#|||||||+||||| + ||+| Sbjct 748 SVEIYDRREYRRFEKEQQQLNWKQDNNPLY#KSAITTTVNPRFQGTNGRSPSL 799 |
| Mus sp. | Query 749 SVEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEAD--SPTL 798 |||||||||| ||||||||||||||+||||#|||||||+||||| + ||+| Sbjct 748 SVEIYDRREYRRFEKEQQQLNWKQDNNPLY#KSAITTTVNPRFQGTNGRSPSL 799 |
| Rattus norvegicus | Query 749 SVEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEADSPTL 798 |||+||| ||||||||+|||||||||||||#|||+|||+||||| + +| Sbjct 582 SVEVYDRLEYSRFEKERQQLNWKQDSNPLY#KSAVTTTVNPRFQGGNKQSL 631 |
| Canis familiaris | Query 749 SVEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEADS 795 |||||||||+|||||||+ |||||++||||#+||||||+||+||| | Sbjct 681 SVEIYDRREFSRFEKEQKHLNWKQENNPLY#RSAITTTVNPQFQETGS 727 |
| Gallus gallus | Query 751 EIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 ||+||||| |||||+ + | + |||+#||| || +|||| Sbjct 730 EIFDRREYRRFEKEKSKAKWNEADNPLF#KSATTTVMNPRF 769 |
| Danio rerio | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 |+||||+ +||||+ | ||+|#|||+|| +|||++ Sbjct 746 IHDRREFDKFEKEKNNAKWDTGENPIY#KSAVTTVVNPRYE 785 |
| Ictalurus punctatus | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 |+||||+++||||+ | ||+|#|||+|| +||+++ Sbjct 766 IHDRREFAKFEKEKMNAKWDAGENPIY#KSAVTTVVNPKYE 805 |
| Bos taurus | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 |+||||+++||||+ | ||+|#|||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKYE 796 |
| Tetraodon nigroviridis | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 |+||||+++||||+ | ||+|#|||+|| +||+++ Sbjct 830 IHDRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKYE 869 |
| Sus scrofa | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 |+||||+++||||+ | ||+|#|||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKYE 796 |
| Xenopus laevis | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 |+||||+++||||+ | ||+|#|||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKYE 796 |
| Pongo pygmaeus | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 |+||||+++||||+ | ||+|#|||+|| +||+++ Sbjct 757 IHDRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKYE 796 |
| Oryctolagus cuniculus | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 |+||||+++||||+ | ||+|#|||+|| +||+++ Sbjct 22 IHDRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKYE 61 |
| Felis catus | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 |+| ||+++||||+ | ||+|#|||+|| +||+++ Sbjct 757 IHDTREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKYE 796 |
| synthetic construct | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEA 793 + + | ||| |||||+ + | | |||+#||| || +||+| |+ Sbjct 727 IHLSDLREYRRFEKEKLKSQWNND-NPLF#KSATTTVMNPKFAES 769 |
| Homo sapiens | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEA 793 + + | ||| |||||+ + | | |||+#||| || +||+| |+ Sbjct 727 IHLSDLREYRRFEKEKLKSQWNND-NPLF#KSATTTVMNPKFAES 769 |
| Ovis aries | Query 754 DRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEA 793 | ||| |||||+ + | | |||+#||| || +||+| |+ Sbjct 732 DLREYHRFEKEKLKSQWNND-NPLF#KSATTTVMNPKFAES 770 |
| Ovis canadensis | Query 754 DRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEA 793 | ||| |||||+ + | | |||+#||| || +||+| |+ Sbjct 732 DLREYHRFEKEKLKSQWNND-NPLF#KSATTTVMNPKFAES 770 |
| Xenopus laevis | Query 751 EIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 || || || |||||+ | ||||# +| || || | Sbjct 730 EIKDRNEYQRFEKERMNSKWNPGHNPLY#HNATTTVQNPNF 769 |
| Sigmodon hispidus | Query 754 DRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEA 793 | ||| ||||+ + | | |||+#||| || +||+| |+ Sbjct 731 DLREYRHFEKEKLKSQWNND-NPLF#KSATTTVMNPKFAES 769 |
| Anopheles gambiae | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 |+||||++|||||+ | ||+|#| | || || + Sbjct 796 IHDRREFARFEKERMMAKWDTGENPIY#KQATTTFKNPTY 834 |
| Anopheles gambiae str. PEST | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 |+||||++|||||+ | ||+|#| | || || + Sbjct 796 IHDRREFARFEKERMMAKWDTGENPIY#KQATTTFKNPTY 834 |
| Pacifastacus leniusculus | Query 753 YDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEA 793 +|||||++||||++ + |+ ||||#||| || || | ++ Sbjct 760 HDRREYAKFEKERKLPSGKRAENPLY#KSAKTTFQNPAFAQS 800 |
| Drosophila melanogaster | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 |+||||++|||||+ | ||+|#| | +| || + Sbjct 805 IHDRREFARFEKERMNAKWDTGENPIY#KQATSTFKNPMY 843 |
| Pseudoplusia includens | Query 753 YDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 +||||++|||||+ | ||+|#| | +| || + Sbjct 797 HDRREFARFEKERMMAKWDTGENPIY#KQATSTFKNPTY 834 |
| Gallus gallus | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 + |+||||++|||+|+ + | +||||#| | +| | ++ Sbjct 737 ITIHDRREFARFEEEKARAKWDTGNNPLY#KEATSTFTNITYR 778 |
| Crassostrea gigas | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQE 792 | |+|| +||||| | ||+|#| | +| +|| +++ Sbjct 759 ISDKRELARFEKEAMNARWDTGENPIY#KQATSTFVNPTYRQ 799 |
| Podocoryne carnea | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 | ||||+++|||++| | ||+|#| | +| || + Sbjct 740 IQDRREFAKFEKDRQNPKWDSGENPIY#KKATSTFQNPMY 778 |
| Biomphalaria glabrata | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 |+| ||+++||||+| | ||+|#| | +| || + Sbjct 747 IHDTREFAKFEKERQNAKWDTGENPIY#KQATSTFKNPTY 785 |
| Strongylocentrotus purpuratus | Query 754 DRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQE 792 | ||++ ||||+ +| |+ ||+|#| + +| || +|+ Sbjct 745 DSREFASFEKERAGTHWGQNENPIY#KPSTSTFKNPTYQK 783 |
| Canis lupus familiaris | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 + |+||+|+++||+|+ + | +||||#| | +| | ++ Sbjct 741 ITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTNITYR 782 |
| Sus scrofa | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 + |+||+|+++||+|+ + | +||||#| | +| | ++ Sbjct 741 ITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTNITYR 782 |
| rats, Peptide Partial, 723 aa | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 + |+||+|+++||+|+ + | +||||#| | +| | ++ Sbjct 680 ITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTNITYR 721 |
| Oryctolagus cuniculus | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 + |+||+|+++||+|+ + | +||||#| | +| | ++ Sbjct 745 ITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTNITYR 786 |
| Acropora millepora | Query 754 DRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 || || +||+|+ | ++ ||||#++| || || + Sbjct 751 DRIEYQKFERERMHSKWTREKNPLY#QAAKTTFENPTY 787 |
| mice, Peptide Partial, 680 aa | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTIN 787 + |+||+|+++||+|+ + | +||||#| | +| | Sbjct 641 ITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTN 678 |
| Mus musculus | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQ 791 + |+||+|+++||+|+ + | +||||#| | +| | ++ Sbjct 744 ITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTNITYR 785 |
| Lytechinus variegatus | Query 752 IYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 |+||||+ ||||+ |+ ||+|#| + + || + Sbjct 765 IHDRREFQNFEKERANATWEGGENPIY#KPSTSVFKNPTY 803 |
| Schistosoma japonicum | Query 750 VEIYDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQE 792 + | |||| + |+++ + + |+ ||++#+| | +|| |+| Sbjct 243 ITIDDRRELANFKQQGENMRWEMAENPIF#ESPTTNVLNPTFEE 285 |
| Caenorhabditis briggsae | Query 753 YDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 +|| ||++| |+ | + ||+|#| | || || + Sbjct 768 HDRAEYAKFNNERLMAKWDTNENPIY#KQATTTFKNPVY 805 |
| Caenorhabditis elegans | Query 753 YDRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 +|| ||+ | |+ | + ||+|#| | || || + Sbjct 767 HDRSEYATFNNERLMAKWDTNENPIY#KQATTTFKNPVY 804 |
| Halocynthia roretzi | Query 754 DRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 |+||| +|+||+ | + ||+|# +| + || | Sbjct 795 DKREYEKFKKEEDLRKWTKGENPVY#VNASSKFDNPMF 831 |
| Cyprinus carpio | Query 754 DRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRF 790 | ||+ ||||+++ +|||+#++| || || | Sbjct 729 DLREWKRFEKDRKHEK-TSGTNPLF#QNATTTIQNPTF 764 |
| Geodia cydonium | Query 754 DRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQE 792 | | +|| | ++ + ++ ||||# || | || + + Sbjct 840 DYTELKKFENELAKVKYTKNENPLY#HSATTEHKNPIYGQ 878 |
[Site 9] NPLYKSAITT784-TINPRFQEAD
Thr784 Thr
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Asn775 | Pro776 | Leu777 | Tyr778 | Lys779 | Ser780 | Ala781 | Ile782 | Thr783 | Thr784 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr785 | Ile786 | Asn787 | Pro788 | Arg789 | Phe790 | Gln791 | Glu792 | Ala793 | Asp794 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| RREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADSPTL |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 99.80 | 10 | integrin, beta 7 |
| 2 | Pan troglodytes | 99.80 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 3 | N/A | 84.00 | 24 | integrin beta-7 subunit |
| 4 | Mus sp. | 84.00 | 1 | beta 7 integrin |
| 5 | Mus musculus | 83.60 | 12 | integrin beta 7 |
| 6 | Rattus norvegicus | 81.60 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 77.80 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Gallus gallus | 55.10 | 3 | integrin, beta 2 |
| 9 | Danio rerio | 54.70 | 6 | integrin, beta 1b.1 |
| 10 | Xenopus laevis | 53.10 | 2 | integrin beta-1 subunit |
| 11 | Ictalurus punctatus | 53.10 | 2 | beta-1 integrin |
| 12 | Bos taurus | 52.80 | 7 | integrin beta 1 |
| 13 | Tetraodon nigroviridis | 52.80 | 5 | unnamed protein product |
| 14 | Sus scrofa | 52.80 | 3 | integrin beta-1 subunit |
| 15 | Pongo pygmaeus | 52.40 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 16 | Oryctolagus cuniculus | 52.00 | 1 | integrin beta 1 |
| 17 | synthetic construct | 51.60 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 18 | Homo sapiens | 51.60 | 1 | integrin, beta 2 precursor |
| 19 | Ovis aries | 50.40 | 2 | antigen CD18 |
| 20 | Ovis canadensis | 50.40 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 21 | Felis catus | 50.40 | 1 | integrin beta 1 |
| 22 | Sigmodon hispidus | 48.10 | 1 | AF445415_1 integrin beta-2 precursor |
| 23 | Pacifastacus leniusculus | 45.80 | 1 | integrin |
| 24 | Pseudoplusia includens | 45.10 | 1 | integrin beta 1 |
| 25 | Xenopus laevis | 45.10 | 1 | hypothetical protein LOC379708 |
| 26 | Anopheles gambiae str. PEST | 44.70 | 1 | integrin beta subunit (AGAP000815-PA) |
| 27 | Anopheles gambiae | 44.70 | 1 | integrin beta subunit |
| 28 | Drosophila melanogaster | 43.90 | 1 | myospheroid CG1560-PA |
| 29 | Strongylocentrotus purpuratus | 43.50 | 3 | integrin beta G subunit |
| 30 | Crassostrea gigas | 43.50 | 1 | integrin beta cgh |
| 31 | Podocoryne carnea | 43.10 | 1 | AF308652_1 integrin beta chain |
| 32 | Biomphalaria glabrata | 42.40 | 1 | beta integrin subunit |
| 33 | Gallus gallus | 42.00 | 2 | integrin, beta 3 precursor |
| 34 | Acropora millepora | 41.20 | 1 | integrin subunit betaCn1 |
| 35 | Schistosoma japonicum | 40.00 | 1 | SJCHGC06221 protein |
| 36 | Lytechinus variegatus | 38.50 | 1 | beta-C integrin subunit |
| 37 | rats, Peptide Partial, 723 aa | 38.50 | 1 | beta 3 integrin, GPIIIA |
| 38 | mice, Peptide Partial, 680 aa | 38.50 | 1 | beta 3 integrin, GPIIIA |
| 39 | Canis lupus familiaris | 38.50 | 1 | integrin beta chain, beta 3 |
| 40 | Sus scrofa | 38.50 | 1 | integrin beta chain, beta 3 |
| 41 | Mus musculus | 38.10 | 1 | integrin beta 3 precursor |
| 42 | Oryctolagus cuniculus | 38.10 | 1 | glycoprotein IIIa |
| 43 | Caenorhabditis briggsae | 38.10 | 1 | Hypothetical protein CBG03601 |
| 44 | Caenorhabditis elegans | 37.00 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 45 | Halocynthia roretzi | 35.40 | 2 | integrin beta Hr2 precursor |
| 46 | Cyprinus carpio | 34.30 | 2 | integrin beta2-chain |
| 47 | Geodia cydonium | 32.70 | 1 | integrin beta subunit |
| 48 | Ophlitaspongia tenuis | 31.60 | 1 | integrin subunit betaPo1 |
| 49 | Anopheles gambiae str. PEST | 31.20 | 1 | AGAP010233-PA |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#|||||||||||||| Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEADSPTL 798 |
| Pan troglodytes | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#|||||||||||||| Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEADSPTL 798 |
| N/A | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEAD--SPTL 798 |||| ||||||||||||||+||||||||||#|+||||| + ||+| Sbjct 753 RREYRRFEKEQQQLNWKQDNNPLYKSAITT#TVNPRFQGTNGRSPSL 798 |
| Mus sp. | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEAD--SPTL 798 |||| ||||||||||||||+||||||||||#|+||||| + ||+| Sbjct 754 RREYRRFEKEQQQLNWKQDNNPLYKSAITT#TVNPRFQGTNGRSPSL 799 |
| Mus musculus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEAD--SPTL 798 |||| ||||||||||||||+||||||||||#|+||||| + ||+| Sbjct 754 RREYRRFEKEQQQLNWKQDNNPLYKSAITT#TVNPRFQGTNGRSPSL 799 |
| Rattus norvegicus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEADSPTL 798 | ||||||||+||||||||||||||||+||#|+||||| + +| Sbjct 588 RLEYSRFEKERQQLNWKQDSNPLYKSAVTT#TVNPRFQGGNKQSL 631 |
| Canis familiaris | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEADS 795 |||+|||||||+ |||||++||||+|||||#|+||+||| | Sbjct 687 RREFSRFEKEQKHLNWKQENNPLYRSAITT#TVNPQFQETGS 727 |
| Gallus gallus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 |||| |||||+ + | + |||+||| ||# +|||| Sbjct 734 RREYRRFEKEKSKAKWNEADNPLFKSATTT#VMNPRF 769 |
| Danio rerio | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |||+ +||||+ | ||+||||+||# +|||++ Sbjct 749 RREFDKFEKEKNNAKWDTGENPIYKSAVTT#VVNPRYE 785 |
| Xenopus laevis | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |||+++||||+ | ||+||||+||# +||+++ Sbjct 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYE 796 |
| Ictalurus punctatus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |||+++||||+ | ||+||||+||# +||+++ Sbjct 769 RREFAKFEKEKMNAKWDAGENPIYKSAVTT#VVNPKYE 805 |
| Bos taurus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |||+++||||+ | ||+||||+||# +||+++ Sbjct 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYE 796 |
| Tetraodon nigroviridis | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |||+++||||+ | ||+||||+||# +||+++ Sbjct 753 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYE 789 |
| Sus scrofa | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |||+++||||+ | ||+||||+||# +||+++ Sbjct 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYE 796 |
| Pongo pygmaeus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |||+++||||+ | ||+||||+||# +||+++ Sbjct 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYE 796 |
| Oryctolagus cuniculus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |||+++||||+ | ||+||||+||# +||+++ Sbjct 25 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYE 61 |
| synthetic construct | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEA 793 ||| |||||+ + | | |||+||| ||# +||+| |+ Sbjct 733 REYRRFEKEKLKSQWNND-NPLFKSATTT#VMNPKFAES 769 |
| Homo sapiens | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEA 793 ||| |||||+ + | | |||+||| ||# +||+| |+ Sbjct 733 REYRRFEKEKLKSQWNND-NPLFKSATTT#VMNPKFAES 769 |
| Ovis aries | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEA 793 ||| |||||+ + | | |||+||| ||# +||+| |+ Sbjct 734 REYHRFEKEKLKSQWNND-NPLFKSATTT#VMNPKFAES 770 |
| Ovis canadensis | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEA 793 ||| |||||+ + | | |||+||| ||# +||+| |+ Sbjct 734 REYHRFEKEKLKSQWNND-NPLFKSATTT#VMNPKFAES 770 |
| Felis catus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 ||+++||||+ | ||+||||+||# +||+++ Sbjct 761 REFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYE 796 |
| Sigmodon hispidus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEA 793 ||| ||||+ + | | |||+||| ||# +||+| |+ Sbjct 733 REYRHFEKEKLKSQWNND-NPLFKSATTT#VMNPKFAES 769 |
| Pacifastacus leniusculus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEA 793 ||||++||||++ + |+ ||||||| ||# || | ++ Sbjct 762 RREYAKFEKERKLPSGKRAENPLYKSAKTT#FQNPAFAQS 800 |
| Pseudoplusia includens | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 |||++|||||+ | ||+|| | +|# || + Sbjct 799 RREFARFEKERMMAKWDTGENPIYKQATST#FKNPTY 834 |
| Xenopus laevis | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 | || |||||+ | |||| +| ||# || | Sbjct 734 RNEYQRFEKERMNSKWNPGHNPLYHNATTT#VQNPNF 769 |
| Anopheles gambiae str. PEST | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 |||++|||||+ | ||+|| | ||# || + Sbjct 799 RREFARFEKERMMAKWDTGENPIYKQATTT#FKNPTY 834 |
| Anopheles gambiae | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 |||++|||||+ | ||+|| | ||# || + Sbjct 799 RREFARFEKERMMAKWDTGENPIYKQATTT#FKNPTY 834 |
| Drosophila melanogaster | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 |||++|||||+ | ||+|| | +|# || + Sbjct 808 RREFARFEKERMNAKWDTGENPIYKQATST#FKNPMY 843 |
| Strongylocentrotus purpuratus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQE 792 ||++ ||||+ +| |+ ||+|| + +|# || +|+ Sbjct 747 REFASFEKERAGTHWGQNENPIYKPSTST#FKNPTYQK 783 |
| Crassostrea gigas | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQE 792 +|| +||||| | ||+|| | +|# +|| +++ Sbjct 762 KRELARFEKEAMNARWDTGENPIYKQATST#FVNPTYRQ 799 |
| Podocoryne carnea | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 |||+++|||++| | ||+|| | +|# || + Sbjct 743 RREFAKFEKDRQNPKWDSGENPIYKKATST#FQNPMY 778 |
| Biomphalaria glabrata | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 ||+++||||+| | ||+|| | +|# || + Sbjct 751 REFAKFEKERQNAKWDTGENPIYKQATST#FKNPTY 785 |
| Gallus gallus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |||++|||+|+ + | +||||| | +|# | ++ Sbjct 742 RREFARFEEEKARAKWDTGNNPLYKEATST#FTNITYR 778 |
| Acropora millepora | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 | || +||+|+ | ++ ||||++| ||# || + Sbjct 752 RIEYQKFERERMHSKWTREKNPLYQAAKTT#FENPTY 787 |
| Schistosoma japonicum | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQE 792 ||| + |+++ + + |+ ||+++| | # +|| |+| Sbjct 248 RRELANFKQQGENMRWEMAENPIFESPTTN#VLNPTFEE 285 |
| Lytechinus variegatus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 |||+ ||||+ |+ ||+|| + + # || + Sbjct 768 RREFQNFEKERANATWEGGENPIYKPSTSV#FKNPTY 803 |
| rats, Peptide Partial, 723 aa | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |+|+++||+|+ + | +||||| | +|# | ++ Sbjct 685 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYR 721 |
| mice, Peptide Partial, 680 aa | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TIN 787 |+|+++||+|+ + | +||||| | +|# | Sbjct 646 RKEFAKFEEERARAKWDTANNPLYKEATST#FTN 678 |
| Canis lupus familiaris | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |+|+++||+|+ + | +||||| | +|# | ++ Sbjct 746 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYR 782 |
| Sus scrofa | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |+|+++||+|+ + | +||||| | +|# | ++ Sbjct 746 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYR 782 |
| Mus musculus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |+|+++||+|+ + | +||||| | +|# | ++ Sbjct 749 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYR 785 |
| Oryctolagus cuniculus | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |+|+++||+|+ + | +||||| | +|# | ++ Sbjct 750 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYR 786 |
| Caenorhabditis briggsae | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 | ||++| |+ | + ||+|| | ||# || + Sbjct 770 RAEYAKFNNERLMAKWDTNENPIYKQATTT#FKNPVY 805 |
| Caenorhabditis elegans | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 | ||+ | |+ | + ||+|| | ||# || + Sbjct 769 RSEYATFNNERLMAKWDTNENPIYKQATTT#FKNPVY 804 |
| Halocynthia roretzi | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 +||| +|+||+ | + ||+| +| + # || | Sbjct 796 KREYEKFKKEEDLRKWTKGENPVYVNASSK#FDNPMF 831 |
| Cyprinus carpio | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 ||+ ||||+++ +|||+++| ||# || | Sbjct 731 REWKRFEKDRKHEK-TSGTNPLFQNATTT#IQNPTF 764 |
| Geodia cydonium | Query 757 EYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQE 792 | +|| | ++ + ++ |||| || | # || + + Sbjct 843 ELKKFENELAKVKYTKNENPLYHSATTE#HKNPIYGQ 878 |
| Ophlitaspongia tenuis | Query 757 EYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRF 790 | +||+| + + ++ ||||+|| # || + Sbjct 803 EVRKFEREIKNAKYTKNENPLYRSATKD#YQNPLY 836 |
| Anopheles gambiae str. PEST | Query 755 RREYSRFEKEQQQLNWKQDSNPLYKSAIT 783 |+ +++||||++| | +||||| |+ Sbjct 762 RKMFAKFEKEREQETKYQMESPLYKSPIS 790 |
[Site 10] PLYKSAITTT785-INPRFQEADS
Thr785 Ile
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Pro776 | Leu777 | Tyr778 | Lys779 | Ser780 | Ala781 | Ile782 | Thr783 | Thr784 | Thr785 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ile786 | Asn787 | Pro788 | Arg789 | Phe790 | Gln791 | Glu792 | Ala793 | Asp794 | Ser795 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| REYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADSPTL |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Pan troglodytes | 97.80 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 2 | Homo sapiens | 97.40 | 10 | integrin, beta 7 |
| 3 | N/A | 81.60 | 24 | integrin beta-7 subunit |
| 4 | Mus musculus | 81.60 | 12 | integrin beta 7 |
| 5 | Mus sp. | 81.60 | 1 | beta 7 integrin |
| 6 | Rattus norvegicus | 80.10 | 5 | integrin beta-7 subunit |
| 7 | Canis familiaris | 75.50 | 10 | PREDICTED: similar to Integrin beta-7 precursor |
| 8 | Gallus gallus | 52.80 | 3 | integrin, beta 2 |
| 9 | Danio rerio | 52.00 | 6 | integrin, beta 1b.1 |
| 10 | synthetic construct | 51.60 | 3 | integrin, beta 2 (antigen CD18 (p95), lymphocyte |
| 11 | Homo sapiens | 51.60 | 1 | integrin, beta 2 precursor |
| 12 | Ovis aries | 50.80 | 2 | antigen CD18 |
| 13 | Ictalurus punctatus | 50.80 | 2 | beta-1 integrin |
| 14 | Bos taurus | 50.40 | 7 | integrin, beta 2 |
| 15 | Tetraodon nigroviridis | 50.40 | 5 | unnamed protein product |
| 16 | Sus scrofa | 50.40 | 3 | CD18 leukocyte adhesion molecule |
| 17 | Xenopus laevis | 50.40 | 2 | integrin beta-1 subunit |
| 18 | Ovis canadensis | 50.40 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 19 | Felis catus | 50.40 | 1 | integrin beta 1 |
| 20 | Pongo pygmaeus | 50.10 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 21 | Oryctolagus cuniculus | 49.70 | 1 | integrin beta 1 |
| 22 | Sigmodon hispidus | 48.10 | 1 | AF445415_1 integrin beta-2 precursor |
| 23 | Strongylocentrotus purpuratus | 43.50 | 3 | integrin beta G subunit |
| 24 | Pacifastacus leniusculus | 43.50 | 1 | integrin |
| 25 | Xenopus laevis | 42.70 | 1 | hypothetical protein LOC379708 |
| 26 | Pseudoplusia includens | 42.70 | 1 | integrin beta 1 |
| 27 | Crassostrea gigas | 42.70 | 1 | integrin beta cgh |
| 28 | Anopheles gambiae str. PEST | 42.40 | 1 | integrin beta subunit (AGAP000815-PA) |
| 29 | Anopheles gambiae | 42.40 | 1 | integrin beta subunit |
| 30 | Biomphalaria glabrata | 42.00 | 1 | beta integrin subunit |
| 31 | Drosophila melanogaster | 41.20 | 1 | myospheroid CG1560-PA |
| 32 | Podocoryne carnea | 40.80 | 1 | AF308652_1 integrin beta chain |
| 33 | Acropora millepora | 40.00 | 1 | integrin subunit betaCn1 |
| 34 | Gallus gallus | 39.70 | 2 | integrin, beta 3 precursor |
| 35 | Schistosoma japonicum | 37.70 | 1 | SJCHGC06221 protein |
| 36 | Caenorhabditis briggsae | 36.60 | 1 | Hypothetical protein CBG03601 |
| 37 | rats, Peptide Partial, 723 aa | 36.20 | 1 | beta 3 integrin, GPIIIA |
| 38 | Canis lupus familiaris | 36.20 | 1 | integrin beta chain, beta 3 |
| 39 | Lytechinus variegatus | 36.20 | 1 | beta-C integrin subunit |
| 40 | mice, Peptide Partial, 680 aa | 36.20 | 1 | beta 3 integrin, GPIIIA |
| 41 | Oryctolagus cuniculus | 36.20 | 1 | glycoprotein IIIa |
| 42 | Mus musculus | 35.80 | 1 | integrin beta 3 precursor |
| 43 | Sus scrofa | 35.80 | 1 | integrin beta chain, beta 3 |
| 44 | Caenorhabditis elegans | 35.00 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 45 | Halocynthia roretzi | 34.70 | 2 | integrin beta Hr2 precursor |
| 46 | Cyprinus carpio | 33.90 | 2 | integrin beta2-chain |
| 47 | Geodia cydonium | 32.30 | 1 | integrin beta subunit |
| 48 | Ophlitaspongia tenuis | 31.20 | 1 | integrin subunit betaPo1 |
Top-ranked sequences
| organism | matching |
|---|---|
| Pan troglodytes | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#||||||||||||| Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEADSPTL 798 |
| Homo sapiens | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEADSPTL 798 ||||||||||||||||||||||||||||||#||||||||||||| Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEADSPTL 798 |
| N/A | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEAD--SPTL 798 ||| ||||||||||||||+|||||||||||#+||||| + ||+| Sbjct 754 REYRRFEKEQQQLNWKQDNNPLYKSAITTT#VNPRFQGTNGRSPSL 798 |
| Mus musculus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEAD--SPTL 798 ||| ||||||||||||||+|||||||||||#+||||| + ||+| Sbjct 755 REYRRFEKEQQQLNWKQDNNPLYKSAITTT#VNPRFQGTNGRSPSL 799 |
| Mus sp. | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEAD--SPTL 798 ||| ||||||||||||||+|||||||||||#+||||| + ||+| Sbjct 755 REYRRFEKEQQQLNWKQDNNPLYKSAITTT#VNPRFQGTNGRSPSL 799 |
| Rattus norvegicus | Query 757 EYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEADSPTL 798 ||||||||+||||||||||||||||+|||#+||||| + +| Sbjct 590 EYSRFEKERQQLNWKQDSNPLYKSAVTTT#VNPRFQGGNKQSL 631 |
| Canis familiaris | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEADS 795 ||+|||||||+ |||||++||||+||||||#+||+||| | Sbjct 688 REFSRFEKEQKHLNWKQENNPLYRSAITTT#VNPQFQETGS 727 |
| Gallus gallus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||| |||||+ + | + |||+||| || #+|||| Sbjct 735 REYRRFEKEKSKAKWNEADNPLFKSATTTV#MNPRF 769 |
| Danio rerio | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 ||+ +||||+ | ||+||||+|| #+|||++ Sbjct 750 REFDKFEKEKNNAKWDTGENPIYKSAVTTV#VNPRYE 785 |
| synthetic construct | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEA 793 ||| |||||+ + | | |||+||| || #+||+| |+ Sbjct 733 REYRRFEKEKLKSQWNND-NPLFKSATTTV#MNPKFAES 769 |
| Homo sapiens | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEA 793 ||| |||||+ + | | |||+||| || #+||+| |+ Sbjct 733 REYRRFEKEKLKSQWNND-NPLFKSATTTV#MNPKFAES 769 |
| Ovis aries | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEA 793 ||| |||||+ + | | |||+||| || #+||+| |+ Sbjct 734 REYHRFEKEKLKSQWNND-NPLFKSATTTV#MNPKFAES 770 |
| Ictalurus punctatus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 ||+++||||+ | ||+||||+|| #+||+++ Sbjct 770 REFAKFEKEKMNAKWDAGENPIYKSAVTTV#VNPKYE 805 |
| Bos taurus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEA 793 ||| |||||+ + | | |||+||| || #+||+| |+ Sbjct 733 REYHRFEKEKLKSQWNND-NPLFKSATTTV#MNPKFAES 769 |
| Tetraodon nigroviridis | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 ||+++||||+ | ||+||||+|| #+||+++ Sbjct 754 REFAKFEKEKMNAKWDTGENPIYKSAVTTV#VNPKYE 789 |
| Sus scrofa | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQE 792 ||| |||||+ + | | |||+||| || #+||+| | Sbjct 733 REYKRFEKEKLKSQWNND-NPLFKSATTTV#MNPKFAE 768 |
| Xenopus laevis | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 ||+++||||+ | ||+||||+|| #+||+++ Sbjct 761 REFAKFEKEKMNAKWDTGENPIYKSAVTTV#VNPKYE 796 |
| Ovis canadensis | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEA 793 ||| |||||+ + | | |||+||| || #+||+| |+ Sbjct 734 REYHRFEKEKLKSQWNND-NPLFKSATTTV#MNPKFAES 770 |
| Felis catus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 ||+++||||+ | ||+||||+|| #+||+++ Sbjct 761 REFAKFEKEKMNAKWDTGENPIYKSAVTTV#VNPKYE 796 |
| Pongo pygmaeus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 ||+++||||+ | ||+||||+|| #+||+++ Sbjct 761 REFAKFEKEKMNAKWDTGENPIYKSAVTTV#VNPKYE 796 |
| Oryctolagus cuniculus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 ||+++||||+ | ||+||||+|| #+||+++ Sbjct 26 REFAKFEKEKMNAKWDTGENPIYKSAVTTV#VNPKYE 61 |
| Sigmodon hispidus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEA 793 ||| ||||+ + | | |||+||| || #+||+| |+ Sbjct 733 REYRHFEKEKLKSQWNND-NPLFKSATTTV#MNPKFAES 769 |
| Strongylocentrotus purpuratus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQE 792 ||++ ||||+ +| |+ ||+|| + +| # || +|+ Sbjct 747 REFASFEKERAGTHWGQNENPIYKPSTSTF#KNPTYQK 783 |
| Pacifastacus leniusculus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQEA 793 |||++||||++ + |+ ||||||| || # || | ++ Sbjct 763 REYAKFEKERKLPSGKRAENPLYKSAKTTF#QNPAFAQS 800 |
| Xenopus laevis | Query 757 EYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 || |||||+ | |||| +| || # || | Sbjct 736 EYQRFEKERMNSKWNPGHNPLYHNATTTV#QNPNF 769 |
| Pseudoplusia includens | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||++|||||+ | ||+|| | +| # || + Sbjct 800 REFARFEKERMMAKWDTGENPIYKQATSTF#KNPTY 834 |
| Crassostrea gigas | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQE 792 || +||||| | ||+|| | +| #+|| +++ Sbjct 763 RELARFEKEAMNARWDTGENPIYKQATSTF#VNPTYRQ 799 |
| Anopheles gambiae str. PEST | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||++|||||+ | ||+|| | || # || + Sbjct 800 REFARFEKERMMAKWDTGENPIYKQATTTF#KNPTY 834 |
| Anopheles gambiae | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||++|||||+ | ||+|| | || # || + Sbjct 800 REFARFEKERMMAKWDTGENPIYKQATTTF#KNPTY 834 |
| Biomphalaria glabrata | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||+++||||+| | ||+|| | +| # || + Sbjct 751 REFAKFEKERQNAKWDTGENPIYKQATSTF#KNPTY 785 |
| Drosophila melanogaster | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||++|||||+ | ||+|| | +| # || + Sbjct 809 REFARFEKERMNAKWDTGENPIYKQATSTF#KNPMY 843 |
| Podocoryne carnea | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||+++|||++| | ||+|| | +| # || + Sbjct 744 REFAKFEKDRQNPKWDSGENPIYKKATSTF#QNPMY 778 |
| Acropora millepora | Query 757 EYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 || +||+|+ | ++ ||||++| || # || + Sbjct 754 EYQKFERERMHSKWTREKNPLYQAAKTTF#ENPTY 787 |
| Gallus gallus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 ||++|||+|+ + | +||||| | +| # | ++ Sbjct 743 REFARFEEEKARAKWDTGNNPLYKEATSTF#TNITYR 778 |
| Schistosoma japonicum | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQE 792 || + |+++ + + |+ ||+++| | #+|| |+| Sbjct 249 RELANFKQQGENMRWEMAENPIFESPTTNV#LNPTFEE 285 |
| Caenorhabditis briggsae | Query 757 EYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||++| |+ | + ||+|| | || # || + Sbjct 772 EYAKFNNERLMAKWDTNENPIYKQATTTF#KNPVY 805 |
| rats, Peptide Partial, 723 aa | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 +|+++||+|+ + | +||||| | +| # | ++ Sbjct 686 KEFAKFEEERARAKWDTANNPLYKEATSTF#TNITYR 721 |
| Canis lupus familiaris | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 +|+++||+|+ + | +||||| | +| # | ++ Sbjct 747 KEFAKFEEERARAKWDTANNPLYKEATSTF#TNITYR 782 |
| Lytechinus variegatus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||+ ||||+ |+ ||+|| + + # || + Sbjct 769 REFQNFEKERANATWEGGENPIYKPSTSVF#KNPTY 803 |
| mice, Peptide Partial, 680 aa | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#IN 787 +|+++||+|+ + | +||||| | +| # | Sbjct 647 KEFAKFEEERARAKWDTANNPLYKEATSTF#TN 678 |
| Oryctolagus cuniculus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 +|+++||+|+ + | +||||| | +| # | ++ Sbjct 751 KEFAKFEEERARAKWDTANNPLYKEATSTF#TNITYR 786 |
| Mus musculus | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 +|+++||+|+ + | +||||| | +| # | ++ Sbjct 750 KEFAKFEEERARAKWDTANNPLYKEATSTF#TNITYR 785 |
| Sus scrofa | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQ 791 +|+++||+|+ + | +||||| | +| # | ++ Sbjct 747 KEFAKFEEERARAKWDTANNPLYKEATSTF#TNITYR 782 |
| Caenorhabditis elegans | Query 757 EYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||+ | |+ | + ||+|| | || # || + Sbjct 771 EYATFNNERLMAKWDTNENPIYKQATTTF#KNPVY 804 |
| Halocynthia roretzi | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||| +|+||+ | + ||+| +| + # || | Sbjct 797 REYEKFKKEEDLRKWTKGENPVYVNASSKF#DNPMF 831 |
| Cyprinus carpio | Query 756 REYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 ||+ ||||+++ +|||+++| || # || | Sbjct 731 REWKRFEKDRKHEK-TSGTNPLFQNATTTI#QNPTF 764 |
| Geodia cydonium | Query 757 EYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRFQE 792 | +|| | ++ + ++ |||| || | # || + + Sbjct 843 ELKKFENELAKVKYTKNENPLYHSATTEH#KNPIYGQ 878 |
| Ophlitaspongia tenuis | Query 757 EYSRFEKEQQQLNWKQDSNPLYKSAITTT#INPRF 790 | +||+| + + ++ ||||+|| # || + Sbjct 803 EVRKFEREIKNAKYTKNENPLYRSATKDY#QNPLY 836 |
* References
[PubMed ID: 24162774] Jelicic K, Cimbro R, Nawaz F, Huang da W, Zheng X, Yang J, Lempicki RA, Pascuccio M, Van Ryk D, Schwing C, Hiatt J, Okwara N, Wei D, Roby G, David A, Hwang IY, Kehrl JH, Arthos J, Cicala C, Fauci AS, The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-beta1 production and FcRL4 expression. Nat Immunol. 2013 Dec;14(12):1256-65. doi: 10.1038/ni.2746. Epub 2013 Oct 27.
[PubMed ID: 23553626] ... Yue J, Pan Y, Sun L, Zhang K, Liu J, Lu L, Chen J, The unique disulfide bond-stabilized W1 beta4-beta1 loop in the alpha4 beta-propeller domain regulates integrin alpha4beta7 affinity and signaling. J Biol Chem. 2013 May 17;288(20):14228-37. doi: 10.1074/jbc.M113.462630. Epub
[PubMed ID: 22822002] ... Li H, Pauza CD, The alpha4beta7 integrin binds HIV envelope but does not mediate bystander killing of gammadelta T cells. Blood. 2012 Jul 19;120(3):698-9. doi: 10.1182/blood-2012-03-420117.
[PubMed ID: 12840763] ... Mora JR, Bono MR, Manjunath N, Weninger W, Cavanagh LL, Rosemblatt M, Von Andrian UH, Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature. 2003 Jul 3;424(6944):88-93.
[PubMed ID: 12682249] ... Hilden TJ, Valmu L, Karkkainen S, Gahmberg CG, Threonine phosphorylation sites in the beta 2 and beta 7 leukocyte integrin polypeptides. J Immunol. 2003 Apr 15;170(8):4170-7.
[PubMed ID: 7509610] ... Erle DJ, Brown T, Christian D, Aris R, Lung epithelial lining fluid T cell subsets defined by distinct patterns of beta 7 and beta 1 integrin expression. Am J Respir Cell Mol Biol. 1994 Mar;10(3):237-44.
[PubMed ID: 1382574] ... Jiang WM, Jenkins D, Yuan Q, Leung E, Choo KH, Watson JD, Krissansen GW, The gene organization of the human beta 7 subunit, the common beta subunit of the leukocyte integrins HML-1 and LPAM-1. Int Immunol. 1992 Sep;4(9):1031-40.
[PubMed ID: 1372909] ... Ruegg C, Postigo AA, Sikorski EE, Butcher EC, Pytela R, Erle DJ, Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering. J Cell Biol. 1992 Apr;117(1):179-89.
[PubMed ID: 1543919] ... Baker E, Sutherland GR, Jiang WM, Yuan Q, Leung E, Watson JD, Krissansen GW, Mapping of the human integrin beta 7 gene (ITG beta 7) to 12q13.13 by non-isotopic in situ hybridization. Mamm Genome. 1992;2(4):272-3.
[PubMed ID: 1777426] ... Yuan QA, Jiang WM, Krissansen GW, Watson JD, Cloning and sequence analysis of a novel beta 2-related integrin transcript from T lymphocytes: homology of integrin cysteine-rich repeats to domain III of laminin B chains. Int Immunol. 1991 Dec;3(12):1373-4.
[PubMed ID: 2040616] ... Erle DJ, Ruegg C, Sheppard D, Pytela R, Complete amino acid sequence of an integrin beta subunit (beta 7) identified in leukocytes. J Biol Chem. 1991 Jun 15;266(17):11009-16.