SB0063 : Integrin [beta]1 isoform 1A
[ CaMP Format ]
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | integrin beta-1 isoform 1A precursor [Homo sapiens]; integrin beta-1 isoform 1A precursor; integrin VLA-4 beta subunit; very late activation protein, beta polypeptide; glycoprotein IIa; Integrin beta-1; Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; VLA-4 subunit beta |
| Gene Names | ITGB1; FNRB, MDF2, MSK12; FNRB; MDF2; MSK12; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| Gene Locus | 10p11.2; chromosome 10 |
| GO Function | Not available |
* Information From OMIM
Function: Arregui et al. (2000) demonstrated that cell-permeable (Trojan) peptides containing the third helix of the antennapedia homeodomain fused to a peptide mimicking the juxtamembrane (JMP) region of the cytoplasmic domain of N-cadherin (CDH2; OMIM:114020) result in the inhibition of both CDH2 and ITGB1 function. Microscopic analysis showed that expression of JMP, which binds to the cytoplasmic domain of CDH2, results in a reduction of neurite outgrowth on cadherin substrates. Treatment of cells with JMP resulted in the release of FER (OMIM:176942) from the cadherin complex and its accumulation in the integrin complex. The accumulation of FER in the integrin complex and the inhibitory effects of JMP could be reversed with a peptide that mimics the first coiled-coil domain of FER. The results suggested that FER mediates crosstalk between CDH2 and ITGB1.
* Structure Information
1. Primary Information
Length: 798 aa
Average Mass: 88.414 kDa
Monoisotopic Mass: 88.357 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Integrin beta tail domain 1. | 33 | 35 | 5.0 | 2.2 |
| EGF-like domain 1. | 36 | 39 | 12.0 | 1.7 |
| Integrin beta tail domain 2. | 207 | 221 | 48.0 | 0.0 |
| Integrin beta tail domain 3. | 413 | 442 | 25.0 | 1.4 |
| EGF-like domain 2. | 476 | 500 | 7.0 | 18.7 |
| EGF-like domain 3. | 516 | 553 | 1.0 | 13.5 |
| Integrin beta tail domain 4. | 579 | 598 | 13.0 | 14.8 |
| EGF-like domain 4. | 599 | 630 | 1.0 | 16.5 |
| EGF-like domain 5. | 638 | 641 | 12.0 | 5.8 |
| Integrin beta cytoplasmic domain 1. | 752 | 795 | 1.0 | 0.4 |
| --- cleavage 771 (inside Integrin beta cytoplasmic domain 752..795) --- | ||||
| --- cleavage 777 (inside Integrin beta cytoplasmic domain 752..795) --- | ||||
| --- cleavage 778 (inside Integrin beta cytoplasmic domain 752..795) --- | ||||
| --- cleavage 789 (inside Integrin beta cytoplasmic domain 752..795) --- | ||||
| --- cleavage 791 (inside Integrin beta cytoplasmic domain 752..795) --- | ||||
3. Sequence Information
Fasta Sequence: SB0063.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Known Structures in PDB: 1K11 (Model; -; B=786-797), 1LHA (Model; -; A=86-543), 3G9W (X-ray; 216 A; C/D=752-785), 3T9K (X-ray; 230 A; A/B=758-769), 3VI3 (X-ray; 290 A; B/D=21-465), 3VI4 (X-ray; 290 A; B/D=21-465), 4DX9 (X-ray; 300 A; 6/7/8/9/B/D/F/H/J/L/N/P/R/T/V/X/Z/b/d/f/h/j/l/n/p/r/t/v/x/z=784-798), 4WJK (X-ray; 185 A; B=21-465), 4WK0 (X-ray; 178 A; B=21-465), 4WK2 (X-ray; 250 A; B=21-465), 4WK4 (X-ray; 250 A; B=21-465)
* Cleavage Information
5 [sites] cleaved by Calpain 2
Source Reference: [PubMed ID: 10571053] Pfaff M, Du X, Ginsberg MH, Calpain cleavage of integrin beta cytoplasmic domains. FEBS Lett. 1999 Oct 22;460(1):17-22.
Cleavage sites (±10aa)
[Site 1] EFAKFEKEKM771-NAKWDTGENP
Met771 
Asn
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu762 | Phe763 | Ala764 | Lys765 | Phe766 | Glu767 | Lys768 | Glu769 | Lys770 | Met771 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Asn772 | Ala773 | Lys774 | Trp775 | Asp776 | Thr777 | Gly778 | Glu779 | Asn780 | Pro781 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 125.00 | 28 | ITB1_RAT Integrin beta-1 precursor (Fibronectin r |
| 2 | Mus musculus | 125.00 | 12 | unnamed protein product |
| 3 | Homo sapiens | 125.00 | 11 | integrin beta 1 isoform 1A precursor |
| 4 | Bos taurus | 125.00 | 7 | integrin beta 1 |
| 5 | Tetraodon nigroviridis | 125.00 | 5 | unnamed protein product |
| 6 | Gallus gallus | 125.00 | 3 | integrin, beta 1 (fibronectin receptor, beta poly |
| 7 | Sus scrofa | 125.00 | 3 | integrin beta-1 subunit |
| 8 | Xenopus laevis | 125.00 | 2 | integrin beta-1 subunit |
| 9 | Pongo pygmaeus | 125.00 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 10 | Danio rerio | 124.00 | 5 | integrin, beta 1a |
| 11 | Ictalurus punctatus | 122.00 | 2 | beta-1 integrin |
| 12 | Felis catus | 122.00 | 1 | integrin beta 1 |
| 13 | Oryctolagus cuniculus | 118.00 | 1 | integrin beta 1 |
| 14 | Anopheles gambiae | 94.70 | 1 | integrin beta subunit |
| 15 | Anopheles gambiae str. PEST | 94.70 | 1 | integrin beta subunit (AGAP000815-PA) |
| 16 | Pseudoplusia includens | 93.60 | 1 | integrin beta 1 |
| 17 | Oryctolagus cuniculus | 87.00 | 1 | glycoprotein IIIa |
| 18 | Crassostrea gigas | 86.70 | 1 | integrin beta cgh |
| 19 | Canis familiaris | 86.30 | 10 | platelet glycoprotein IIIa |
| 20 | Rattus norvegicus | 86.30 | 5 | integrin beta 3 |
| 21 | synthetic construct | 86.30 | 3 | AF239959_1 hybrid integrin beta 3 subunit precurs |
| 22 | Canis lupus familiaris | 86.30 | 1 | integrin beta chain, beta 3 |
| 23 | rats, Peptide Partial, 723 aa | 86.30 | 1 | beta 3 integrin, GPIIIA |
| 24 | Sus scrofa | 86.30 | 1 | integrin beta chain, beta 3 |
| 25 | Mus musculus | 86.30 | 1 | integrin beta 3 precursor |
| 26 | mice, Peptide Partial, 680 aa | 82.40 | 1 | beta 3 integrin, GPIIIA |
| 27 | Drosophila melanogaster | 80.50 | 1 | myospheroid CG1560-PA |
| 28 | Xenopus laevis | 78.60 | 1 | hypothetical protein LOC379708 |
| 29 | Gallus gallus | 76.60 | 2 | integrin, beta 3 precursor |
| 30 | Ovis aries | 73.90 | 2 | ITB6_SHEEP Integrin beta-6 precursor gi |
| 31 | Biomphalaria glabrata | 72.80 | 1 | beta integrin subunit |
| 32 | Pan troglodytes | 69.70 | 2 | integrin, beta 2 |
| 33 | Homo sapiens | 69.70 | 1 | integrin, beta 2 precursor |
| 34 | Mus sp. | 69.70 | 1 | beta 7 integrin |
| 35 | Podocoryne carnea | 68.20 | 1 | AF308652_1 integrin beta chain |
| 36 | Caenorhabditis briggsae | 65.10 | 1 | Hypothetical protein CBG03601 |
| 37 | Caenorhabditis elegans | 63.20 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 38 | Halocynthia roretzi | 60.80 | 1 | integrin beta Hr2 precursor |
| 39 | Strongylocentrotus purpuratus | 60.10 | 2 | integrin beta-C subunit |
| 40 | Ovis canadensis | 59.70 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 41 | Lytechinus variegatus | 57.80 | 1 | beta-C integrin subunit |
| 42 | Sigmodon hispidus | 57.00 | 1 | AF445415_1 integrin beta-2 precursor |
| 43 | Schistosoma japonicum | 56.20 | 1 | SJCHGC06221 protein |
| 44 | Acropora millepora | 53.10 | 1 | integrin subunit betaCn1 |
| 45 | Macaca mulatta | 52.40 | 1 | integrin beta 1 |
| 46 | Pacifastacus leniusculus | 50.80 | 1 | integrin |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Mus musculus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Homo sapiens | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Bos taurus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Tetraodon nigroviridis | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Gallus gallus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Sus scrofa | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Xenopus laevis | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Pongo pygmaeus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Danio rerio | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||+||||||| Sbjct 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVINPKYEGK 798 |
| Ictalurus punctatus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||| ||||||||||||||||||||||#||||| ||||||||||||||||||||| Sbjct 751 LIGLALLFIWKLLMIIHDRREFAKFEKEKM#NAKWDAGENPIYKSAVTTVVNPKYEGK 807 |
| Felis catus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |||||||||||||||||| |||||||||||#||||||||||||||||||||||||||| Sbjct 742 LIGLALLLIWKLLMIIHDTREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Oryctolagus cuniculus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |
| Anopheles gambiae | Query 744 GLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |+|+||+||+| ||||||||+||||+|# |||||||||||| | || || | || Sbjct 783 GMAVLLLWKVLTSIHDRREFARFEKERM#MAKWDTGENPIYKQATTTFKNPTYAGK 837 |
| Anopheles gambiae str. PEST | Query 744 GLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |+|+||+||+| ||||||||+||||+|# |||||||||||| | || || | || Sbjct 783 GMAVLLLWKVLTSIHDRREFARFEKERM#MAKWDTGENPIYKQATTTFKNPTYAGK 837 |
| Pseudoplusia includens | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |+|||||++||+ |||||||+||||+|# |||||||||||| | +| || | || Sbjct 781 LVGLALLMLWKMATTSHDRREFARFEKERM#MAKWDTGENPIYKQATSTFKNPTYAGK 837 |
| Oryctolagus cuniculus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 ||| |||||||||+ ||||+||||||+|+ # ||||| ||+|| | +| | | | Sbjct 732 LIGFALLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYRG 787 |
| Crassostrea gigas | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKY 795 |+ ||||||| | |+|| |+|||| |#||+|||||||||| | +| ||| | Sbjct 744 FFGIILLLIWKLFTTISDKRELARFEKEAM#NARWDTGENPIYKQATSTFVNPTY 797 |
| Canis familiaris | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 ||||| |||||||+ ||||+||||||+|+ # ||||| ||+|| | +| | | | Sbjct 728 LIGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYRG 783 |
| Rattus norvegicus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 ||||| |||||||+ ||||+||||||+|+ # ||||| ||+|| | +| | | | Sbjct 731 LIGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYRG 786 |
| synthetic construct | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 ||||| |||||||+ ||||+||||||+|+ # ||||| ||+|| | +| | | | Sbjct 732 LIGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYRG 787 |
| Canis lupus familiaris | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 ||||| |||||||+ ||||+||||||+|+ # ||||| ||+|| | +| | | | Sbjct 728 LIGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYRG 783 |
| rats, Peptide Partial, 723 aa | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 ||||| |||||||+ ||||+||||||+|+ # ||||| ||+|| | +| | | | Sbjct 667 LIGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYRG 722 |
| Sus scrofa | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 ||||| |||||||+ ||||+||||||+|+ # ||||| ||+|| | +| | | | Sbjct 728 LIGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYRG 783 |
| Mus musculus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 ||||| |||||||+ ||||+||||||+|+ # ||||| ||+|| | +| | | | Sbjct 731 LIGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTNITYRG 786 |
| mice, Peptide Partial, 680 aa | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVN 792 ||||| |||||||+ ||||+||||||+|+ # ||||| ||+|| | +| | Sbjct 628 LIGLATLLIWKLLITIHDRKEFAKFEEERA#RAKWDTANNPLYKEATSTFTN 678 |
| Drosophila melanogaster | Query 757 IHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||||||||+||||+|#||||||||||||| | +| || | || Sbjct 805 IHDRREFARFEKERM#NAKWDTGENPIYKQATSTFKNPMYAGK 846 |
| Xenopus laevis | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |||| |+|||++ | || |+ +||||+|#|+||+ | ||+| +| ||| || + |+ Sbjct 716 FIGLACLIIWKIITEIKDRNEYQRFEKERM#NSKWNPGHNPLYHNATTTVQNPNFSGE 772 |
| Gallus gallus | Query 751 WKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 ||||+ ||||||||+||+|| # |||||| ||+|| | +| | | | Sbjct 733 WKLLITIHDRREFARFEEEKA#RAKWDTGNNPLYKEATSTFTNITYRG 779 |
| Ovis aries | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |||+||| |||||+ |||+| |||| |+ # ||| || ||+|+ + +| | |+ | Sbjct 720 LIGVALLCIWKLLVSFHDRKEVAKFEAERS#KAKWQTGTNPLYRGSTSTFKNVTYKHK 776 |
| Biomphalaria glabrata | Query 757 IHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKY 795 ||| |||||||||+ #||||||||||||| | +| || | Sbjct 747 IHDTREFAKFEKERQ#NAKWDTGENPIYKQATSTFKNPTY 785 |
| Pan troglodytes | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKY 795 |||+ ||+||| |+ + | ||+ +|||||+# ++|+ +||++||| |||+|||+ Sbjct 714 LIGILLLVIWKALIHLSDLREYRRFEKEKL#KSQWNN-DNPLFKSATTTVMNPKF 766 |
| Homo sapiens | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKY 795 |||+ ||+||| |+ + | ||+ +|||||+# ++|+ +||++||| |||+|||+ Sbjct 714 LIGILLLVIWKALIHLSDLREYRRFEKEKL#KSQWNN-DNPLFKSATTTVMNPKF 766 |
| Mus sp. | Query 743 IGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 +|| |+| ++| + |+||||+ +||||+ # | ||+||||+|| |||+++| Sbjct 737 VGLGLVLAYRLSVEIYDRREYRRFEKEQQ#QLNWKQDNNPLYKSAITTTVNPRFQG 791 |
| Podocoryne carnea | Query 757 IHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 | ||||||||||++ #| |||+||||||| | +| || | | Sbjct 740 IQDRREFAKFEKDRQ#NPKWDSGENPIYKKATSTFQNPMYGNK 781 |
| Caenorhabditis briggsae | Query 758 HDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||| |+||| |++# ||||| |||||| | || || | || Sbjct 768 HDRAEYAKFNNERL#MAKWDTNENPIYKQATTTFKNPVYAGK 808 |
| Caenorhabditis elegans | Query 758 HDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||| |+| | |++# ||||| |||||| | || || | || Sbjct 767 HDRSEYATFNNERL#MAKWDTNENPIYKQATTTFKNPVYAGK 807 |
| Halocynthia roretzi | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 |||+ |+|||++ + |+||+ ||+||+ # || ||||+| +| + || + | Sbjct 778 LIGIIALIIWKVIQTLRDKREYEKFKKEED#LRKWTKGENPVYVNASSKFDNPMFGG 833 |
| Strongylocentrotus purpuratus | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 |+||||||||+|| ||||||| ||||+ #|| |+ ||||||| + + || | | Sbjct 750 LVGLALLLIWRLLTYIHDRREFQNFEKERA#NATWEGGENPIYKPSTSVFKNPTYNIK 806 |
| Ovis canadensis | Query 750 IWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKY 795 ||| | + | ||+ +|||||+# ++|+ +||++||| |||+|||+ Sbjct 723 IWKALTHLSDLREYHRFEKEKL#KSQWNN-DNPLFKSATTTVMNPKF 767 |
| Lytechinus variegatus | Query 750 IWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEGK 798 ||+|| ||||||| ||||+ #|| |+ ||||||| + + || | | Sbjct 758 IWRLLTYIHDRREFQNFEKERA#NATWEGGENPIYKPSTSVFKNPTYNIK 806 |
| Sigmodon hispidus | Query 748 LLIWKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKY 795 |+||| | + | ||+ |||||+# ++|+ +||++||| |||+|||+ Sbjct 720 LVIWKALTHLTDLREYRHFEKEKL#KSQWNN-DNPLFKSATTTVMNPKF 766 |
| Schistosoma japonicum | Query 751 WKLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYE 796 +||++ | |||| | |+++ #| +|+ ||||++| | |+|| +| Sbjct 239 YKLVITIDDRRELANFKQQGE#NMRWEMAENPIFESPTTNVLNPTFE 284 |
| Acropora millepora | Query 752 KLLMIIHDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKYEG 797 | | + || |+ |||+|+|#++|| +||+|++| || || | | Sbjct 744 KGLFTMVDRIEYQKFERERM#HSKWTREKNPLYQAAKTTFENPTYAG 789 |
| Macaca mulatta | Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKW 775 ||||||||||||||||||||||||||||||#|||| Query 742 LIGLALLLIWKLLMIIHDRREFAKFEKEKM#NAKW 775 |
| Pacifastacus leniusculus | Query 758 HDRREFAKFEKEKM#NAKWDTGENPIYKSAVTTVVNPKY 795 |||||+||||||+ # |||+|||| || || + Sbjct 760 HDRREYAKFEKERK#LPSGKRAENPLYKSAKTTFQNPAF 797 |
[Site 2] KEKMNAKWDT777-GENPIYKSAV
Thr777 Gly
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Lys768 | Glu769 | Lys770 | Met771 | Asn772 | Ala773 | Lys774 | Trp775 | Asp776 | Thr777 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Gly778 | Glu779 | Asn780 | Pro781 | Ile782 | Tyr783 | Lys784 | Ser785 | Ala786 | Val787 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 114.00 | 28 | ITB1_RAT Integrin beta-1 precursor (Fibronectin r |
| 2 | Mus musculus | 114.00 | 12 | integrin beta 1 (fibronectin receptor beta) |
| 3 | Homo sapiens | 114.00 | 11 | integrin beta 1 isoform 1A precursor |
| 4 | Bos taurus | 114.00 | 7 | integrin beta 1 |
| 5 | Tetraodon nigroviridis | 114.00 | 5 | unnamed protein product |
| 6 | Danio rerio | 114.00 | 5 | integrin, beta 1a |
| 7 | Sus scrofa | 114.00 | 3 | integrin beta-1 subunit |
| 8 | Gallus gallus | 114.00 | 3 | integrin, beta 1 (fibronectin receptor, beta poly |
| 9 | Xenopus laevis | 114.00 | 2 | integrin beta-1 subunit |
| 10 | Pongo pygmaeus | 114.00 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 11 | Felis catus | 112.00 | 1 | integrin beta 1 |
| 12 | Ictalurus punctatus | 111.00 | 2 | beta-1 integrin |
| 13 | Oryctolagus cuniculus | 108.00 | 1 | integrin beta 1 |
| 14 | Anopheles gambiae | 89.70 | 1 | integrin beta subunit |
| 15 | Anopheles gambiae str. PEST | 89.70 | 1 | integrin beta subunit (AGAP000815-PA) |
| 16 | Pseudoplusia includens | 84.00 | 1 | integrin beta 1 |
| 17 | Crassostrea gigas | 82.40 | 1 | integrin beta cgh |
| 18 | Drosophila melanogaster | 80.50 | 1 | myospheroid CG1560-PA |
| 19 | Canis familiaris | 78.20 | 10 | PREDICTED: similar to integrin beta 1 isoform 1D |
| 20 | Rattus norvegicus | 77.80 | 5 | integrin beta 3 |
| 21 | synthetic construct | 77.80 | 3 | AF239959_1 hybrid integrin beta 3 subunit precurs |
| 22 | Canis lupus familiaris | 77.80 | 1 | integrin beta chain, beta 3 |
| 23 | Oryctolagus cuniculus | 77.80 | 1 | glycoprotein IIIa |
| 24 | Mus musculus | 77.80 | 1 | integrin beta 3 precursor |
| 25 | rats, Peptide Partial, 723 aa | 77.80 | 1 | beta 3 integrin, GPIIIA |
| 26 | Sus scrofa | 77.80 | 1 | integrin beta chain, beta 3 |
| 27 | Gallus gallus | 76.60 | 2 | integrin, beta 3 precursor |
| 28 | mice, Peptide Partial, 680 aa | 74.30 | 1 | beta 3 integrin, GPIIIA |
| 29 | Biomphalaria glabrata | 72.80 | 1 | beta integrin subunit |
| 30 | Xenopus laevis | 71.60 | 1 | hypothetical protein LOC379708 |
| 31 | Podocoryne carnea | 68.20 | 1 | AF308652_1 integrin beta chain |
| 32 | Ovis aries | 65.10 | 2 | ITB6_SHEEP Integrin beta-6 precursor gi |
| 33 | Caenorhabditis briggsae | 65.10 | 1 | Hypothetical protein CBG03601 |
| 34 | Caenorhabditis elegans | 63.20 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 35 | Mus sp. | 62.80 | 1 | beta 7 integrin |
| 36 | Pan troglodytes | 62.40 | 2 | integrin, beta 2 |
| 37 | Homo sapiens | 62.40 | 1 | integrin, beta 2 precursor |
| 38 | Strongylocentrotus purpuratus | 61.60 | 3 | integrin beta-C subunit |
| 39 | Lytechinus variegatus | 61.60 | 1 | beta-C integrin subunit |
| 40 | Ovis canadensis | 59.70 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 41 | Sigmodon hispidus | 58.20 | 1 | AF445415_1 integrin beta-2 precursor |
| 42 | Schistosoma japonicum | 56.20 | 1 | SJCHGC06221 protein |
| 43 | Halocynthia roretzi | 55.80 | 1 | integrin beta Hr2 precursor |
| 44 | Acropora millepora | 53.10 | 1 | integrin subunit betaCn1 |
| 45 | Macaca mulatta | 51.60 | 1 | integrin beta 1 |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Mus musculus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Homo sapiens | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Bos taurus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Tetraodon nigroviridis | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Danio rerio | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||+||||||| Sbjct 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVINPKYEGK 798 |
| Sus scrofa | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Gallus gallus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Xenopus laevis | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Pongo pygmaeus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Felis catus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |||||||||||| |||||||||||||||||#||||||||||||||||||||| Sbjct 748 LLIWKLLMIIHDTREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Ictalurus punctatus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 | ||||||||||||||||||||||||||| #||||||||||||||||||||| Sbjct 757 LFIWKLLMIIHDRREFAKFEKEKMNAKWDA#GENPIYKSAVTTVVNPKYEGK 807 |
| Oryctolagus cuniculus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||||||||||| Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |
| Anopheles gambiae | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||+||+| ||||||||+||||+| |||||#||||||| | || || | || Sbjct 787 LLLWKVLTSIHDRREFARFEKERMMAKWDT#GENPIYKQATTTFKNPTYAGK 837 |
| Anopheles gambiae str. PEST | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||+||+| ||||||||+||||+| |||||#||||||| | || || | || Sbjct 787 LLLWKVLTSIHDRREFARFEKERMMAKWDT#GENPIYKQATTTFKNPTYAGK 837 |
| Pseudoplusia includens | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |++||+ |||||||+||||+| |||||#||||||| | +| || | || Sbjct 787 LMLWKMATTSHDRREFARFEKERMMAKWDT#GENPIYKQATSTFKNPTYAGK 837 |
| Crassostrea gigas | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKY 795 |||||| | |+|| |+|||| |||+|||#||||||| | +| ||| | Sbjct 750 LLIWKLFTTISDKRELARFEKEAMNARWDT#GENPIYKQATSTFVNPTY 797 |
| Drosophila melanogaster | Query 757 IHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||||+||||+|||||||#||||||| | +| || | || Sbjct 805 IHDRREFARFEKERMNAKWDT#GENPIYKQATSTFKNPMYAGK 846 |
| Canis familiaris | Query 755 MIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |||||||||||||||||||||||# ||||||| + || | | Sbjct 778 MIIHDRREFAKFEKEKMNAKWDT#QENPIYKSPINNFKNPNYGRK 821 |
| Rattus norvegicus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 |||||||+ ||||+||||||+|+ |||||# ||+|| | +| | | | Sbjct 737 LLIWKLLITIHDRKEFAKFEEERARAKWDT#ANNPLYKEATSTFTNITYRG 786 |
| synthetic construct | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 |||||||+ ||||+||||||+|+ |||||# ||+|| | +| | | | Sbjct 738 LLIWKLLITIHDRKEFAKFEEERARAKWDT#ANNPLYKEATSTFTNITYRG 787 |
| Canis lupus familiaris | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 |||||||+ ||||+||||||+|+ |||||# ||+|| | +| | | | Sbjct 734 LLIWKLLITIHDRKEFAKFEEERARAKWDT#ANNPLYKEATSTFTNITYRG 783 |
| Oryctolagus cuniculus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 |||||||+ ||||+||||||+|+ |||||# ||+|| | +| | | | Sbjct 738 LLIWKLLITIHDRKEFAKFEEERARAKWDT#ANNPLYKEATSTFTNITYRG 787 |
| Mus musculus | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 |||||||+ ||||+||||||+|+ |||||# ||+|| | +| | | | Sbjct 737 LLIWKLLITIHDRKEFAKFEEERARAKWDT#ANNPLYKEATSTFTNITYRG 786 |
| rats, Peptide Partial, 723 aa | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 |||||||+ ||||+||||||+|+ |||||# ||+|| | +| | | | Sbjct 673 LLIWKLLITIHDRKEFAKFEEERARAKWDT#ANNPLYKEATSTFTNITYRG 722 |
| Sus scrofa | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 |||||||+ ||||+||||||+|+ |||||# ||+|| | +| | | | Sbjct 734 LLIWKLLITIHDRKEFAKFEEERARAKWDT#ANNPLYKEATSTFTNITYRG 783 |
| Gallus gallus | Query 751 WKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 ||||+ ||||||||+||+|| |||||#| ||+|| | +| | | | Sbjct 733 WKLLITIHDRREFARFEEEKARAKWDT#GNNPLYKEATSTFTNITYRG 779 |
| mice, Peptide Partial, 680 aa | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVN 792 |||||||+ ||||+||||||+|+ |||||# ||+|| | +| | Sbjct 634 LLIWKLLITIHDRKEFAKFEEERARAKWDT#ANNPLYKEATSTFTN 678 |
| Biomphalaria glabrata | Query 757 IHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKY 795 ||| |||||||||+ ||||||#||||||| | +| || | Sbjct 747 IHDTREFAKFEKERQNAKWDT#GENPIYKQATSTFKNPTY 785 |
| Xenopus laevis | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 |+|||++ | || |+ +||||+||+||+ #| ||+| +| ||| || + |+ Sbjct 722 LIIWKIITEIKDRNEYQRFEKERMNSKWNP#GHNPLYHNATTTVQNPNFSGE 772 |
| Podocoryne carnea | Query 757 IHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 | ||||||||||++ | |||+#||||||| | +| || | | Sbjct 740 IQDRREFAKFEKDRQNPKWDS#GENPIYKKATSTFQNPMYGNK 781 |
| Ovis aries | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 | |||||+ |||+| |||| |+ ||| |#| ||+|+ + +| | |+ | Sbjct 726 LCIWKLLVSFHDRKEVAKFEAERSKAKWQT#GTNPLYRGSTSTFKNVTYKHK 776 |
| Caenorhabditis briggsae | Query 758 HDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||| |+||| |++ |||||# |||||| | || || | || Sbjct 768 HDRAEYAKFNNERLMAKWDT#NENPIYKQATTTFKNPVYAGK 808 |
| Caenorhabditis elegans | Query 758 HDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||| |+| | |++ |||||# |||||| | || || | || Sbjct 767 HDRSEYATFNNERLMAKWDT#NENPIYKQATTTFKNPVYAGK 807 |
| Mus sp. | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 +| ++| + |+||||+ +||||+ | # ||+||||+|| |||+++| Sbjct 742 VLAYRLSVEIYDRREYRRFEKEQQQLNWKQ#DNNPLYKSAITTTVNPRFQG 791 |
| Pan troglodytes | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKY 795 |+||| |+ + | ||+ +|||||+ ++|+ # +||++||| |||+|||+ Sbjct 720 LVIWKALIHLSDLREYRRFEKEKLKSQWNN#-DNPLFKSATTTVMNPKF 766 |
| Homo sapiens | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKY 795 |+||| |+ + | ||+ +|||||+ ++|+ # +||++||| |||+|||+ Sbjct 720 LVIWKALIHLSDLREYRRFEKEKLKSQWNN#-DNPLFKSATTTVMNPKF 766 |
| Strongylocentrotus purpuratus | Query 757 IHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||| ||||+ || |+ #||||||| + + || | | Sbjct 765 IHDRREFQNFEKERANATWEG#GENPIYKPSTSVFKNPTYNIK 806 |
| Lytechinus variegatus | Query 757 IHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEGK 798 ||||||| ||||+ || |+ #||||||| + + || | | Sbjct 765 IHDRREFQNFEKERANATWEG#GENPIYKPSTSVFKNPTYNIK 806 |
| Ovis canadensis | Query 750 IWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKY 795 ||| | + | ||+ +|||||+ ++|+ # +||++||| |||+|||+ Sbjct 723 IWKALTHLSDLREYHRFEKEKLKSQWNN#-DNPLFKSATTTVMNPKF 767 |
| Sigmodon hispidus | Query 750 IWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKY 795 ||| | + | ||+ |||||+ ++|+ # +||++||| |||+|||+ Sbjct 722 IWKALTHLTDLREYRHFEKEKLKSQWNN#-DNPLFKSATTTVMNPKF 766 |
| Schistosoma japonicum | Query 751 WKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYE 796 +||++ | |||| | |+++ | +|+ # ||||++| | |+|| +| Sbjct 239 YKLVITIDDRRELANFKQQGENMRWEM#AENPIFESPTTNVLNPTFE 284 |
| Halocynthia roretzi | Query 748 LLIWKLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 |+|||++ + |+||+ ||+||+ || #||||+| +| + || + | Sbjct 784 LIIWKVIQTLRDKREYEKFKKEEDLRKWTK#GENPVYVNASSKFDNPMFGG 833 |
| Acropora millepora | Query 752 KLLMIIHDRREFAKFEKEKMNAKWDT#GENPIYKSAVTTVVNPKYEG 797 | | + || |+ |||+|+|++|| # +||+|++| || || | | Sbjct 744 KGLFTMVDRIEYQKFERERMHSKWTR#EKNPLYQAAKTTFENPTYAG 789 |
| Macaca mulatta | Query 755 MIIHDRREFAKFEKEKMNAKW 775 ||||||||||||||||||||| Query 755 MIIHDRREFAKFEKEKMNAKW 775 |
[Site 3] EKMNAKWDTG778-ENPIYKSAVT
Gly778 Glu
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu769 | Lys770 | Met771 | Asn772 | Ala773 | Lys774 | Trp775 | Asp776 | Thr777 | Gly778 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Glu779 | Asn780 | Pro781 | Ile782 | Tyr783 | Lys784 | Ser785 | Ala786 | Val787 | Thr788 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 113.00 | 28 | ITB1_RAT Integrin beta-1 precursor (Fibronectin r |
| 2 | Mus musculus | 113.00 | 12 | unnamed protein product |
| 3 | Homo sapiens | 113.00 | 11 | integrin beta 1 isoform 1A precursor |
| 4 | Bos taurus | 113.00 | 7 | integrin beta 1 |
| 5 | Tetraodon nigroviridis | 113.00 | 5 | unnamed protein product |
| 6 | Gallus gallus | 113.00 | 3 | integrin, beta 1 (fibronectin receptor, beta poly |
| 7 | Sus scrofa | 113.00 | 3 | integrin beta-1 subunit |
| 8 | Xenopus laevis | 113.00 | 2 | integrin beta-1 subunit |
| 9 | Pongo pygmaeus | 113.00 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 10 | Danio rerio | 112.00 | 5 | integrin, beta 1a |
| 11 | Felis catus | 110.00 | 1 | integrin beta 1 |
| 12 | Ictalurus punctatus | 109.00 | 2 | beta-1 integrin |
| 13 | Oryctolagus cuniculus | 106.00 | 1 | integrin beta 1 |
| 14 | Anopheles gambiae | 88.20 | 1 | integrin beta subunit |
| 15 | Anopheles gambiae str. PEST | 88.20 | 1 | integrin beta subunit (AGAP000815-PA) |
| 16 | Pseudoplusia includens | 82.40 | 1 | integrin beta 1 |
| 17 | Crassostrea gigas | 80.90 | 1 | integrin beta cgh |
| 18 | Drosophila melanogaster | 80.50 | 1 | myospheroid CG1560-PA |
| 19 | Canis familiaris | 78.20 | 10 | PREDICTED: similar to integrin beta 1 isoform 1D |
| 20 | Gallus gallus | 76.60 | 2 | integrin, beta 3 precursor |
| 21 | Rattus norvegicus | 76.30 | 5 | integrin beta 3 |
| 22 | synthetic construct | 76.30 | 3 | AF239959_1 hybrid integrin beta 3 subunit precurs |
| 23 | Sus scrofa | 76.30 | 1 | integrin beta chain, beta 3 |
| 24 | Mus musculus | 76.30 | 1 | integrin beta 3 precursor |
| 25 | rats, Peptide Partial, 723 aa | 76.30 | 1 | beta 3 integrin, GPIIIA |
| 26 | Canis lupus familiaris | 76.30 | 1 | integrin beta chain, beta 3 |
| 27 | Oryctolagus cuniculus | 76.30 | 1 | glycoprotein IIIa |
| 28 | Biomphalaria glabrata | 72.80 | 1 | beta integrin subunit |
| 29 | mice, Peptide Partial, 680 aa | 72.40 | 1 | beta 3 integrin, GPIIIA |
| 30 | Xenopus laevis | 70.10 | 1 | hypothetical protein LOC379708 |
| 31 | Podocoryne carnea | 68.20 | 1 | AF308652_1 integrin beta chain |
| 32 | Caenorhabditis briggsae | 65.10 | 1 | Hypothetical protein CBG03601 |
| 33 | Ovis aries | 63.90 | 2 | ITB6_SHEEP Integrin beta-6 precursor gi |
| 34 | Caenorhabditis elegans | 63.20 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 35 | Mus sp. | 62.80 | 1 | beta 7 integrin |
| 36 | Strongylocentrotus purpuratus | 61.60 | 3 | integrin beta-C subunit |
| 37 | Lytechinus variegatus | 61.60 | 1 | beta-C integrin subunit |
| 38 | Pan troglodytes | 60.80 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 39 | Homo sapiens | 60.80 | 1 | integrin, beta 2 precursor |
| 40 | Ovis canadensis | 59.70 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 41 | Sigmodon hispidus | 58.20 | 1 | AF445415_1 integrin beta-2 precursor |
| 42 | Schistosoma japonicum | 56.20 | 1 | SJCHGC06221 protein |
| 43 | Halocynthia roretzi | 54.30 | 1 | integrin beta Hr2 precursor |
| 44 | Acropora millepora | 53.10 | 1 | integrin subunit betaCn1 |
| 45 | Macaca mulatta | 51.60 | 1 | integrin beta 1 |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Mus musculus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Homo sapiens | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Bos taurus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Tetraodon nigroviridis | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Gallus gallus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Sus scrofa | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Xenopus laevis | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Pongo pygmaeus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Danio rerio | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||||||+||||||| Sbjct 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVINPKYEGK 798 |
| Felis catus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||| ||||||||||||||||||#|||||||||||||||||||| Sbjct 749 LIWKLLMIIHDTREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Ictalurus punctatus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||| |#|||||||||||||||||||| Sbjct 758 FIWKLLMIIHDRREFAKFEKEKMNAKWDAG#ENPIYKSAVTTVVNPKYEGK 807 |
| Oryctolagus cuniculus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||||||||||#|||||||||||||||||||| Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |
| Anopheles gambiae | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |+||+| ||||||||+||||+| ||||||#|||||| | || || | || Sbjct 788 LLWKVLTSIHDRREFARFEKERMMAKWDTG#ENPIYKQATTTFKNPTYAGK 837 |
| Anopheles gambiae str. PEST | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |+||+| ||||||||+||||+| ||||||#|||||| | || || | || Sbjct 788 LLWKVLTSIHDRREFARFEKERMMAKWDTG#ENPIYKQATTTFKNPTYAGK 837 |
| Pseudoplusia includens | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ++||+ |||||||+||||+| ||||||#|||||| | +| || | || Sbjct 788 MLWKMATTSHDRREFARFEKERMMAKWDTG#ENPIYKQATSTFKNPTYAGK 837 |
| Crassostrea gigas | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKY 795 ||||| | |+|| |+|||| |||+||||#|||||| | +| ||| | Sbjct 751 LIWKLFTTISDKRELARFEKEAMNARWDTG#ENPIYKQATSTFVNPTY 797 |
| Drosophila melanogaster | Query 757 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||+||||+||||||||#|||||| | +| || | || Sbjct 805 IHDRREFARFEKERMNAKWDTG#ENPIYKQATSTFKNPMYAGK 846 |
| Canis familiaris | Query 755 MIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||||||||||||||||||| #||||||| + || | | Sbjct 778 MIIHDRREFAKFEKEKMNAKWDTQ#ENPIYKSPINNFKNPNYGRK 821 |
| Gallus gallus | Query 751 WKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 ||||+ ||||||||+||+|| ||||||# ||+|| | +| | | | Sbjct 733 WKLLITIHDRREFARFEEEKARAKWDTG#NNPLYKEATSTFTNITYRG 779 |
| Rattus norvegicus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 ||||||+ ||||+||||||+|+ ||||| # ||+|| | +| | | | Sbjct 738 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYRG 786 |
| synthetic construct | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 ||||||+ ||||+||||||+|+ ||||| # ||+|| | +| | | | Sbjct 739 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYRG 787 |
| Sus scrofa | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 ||||||+ ||||+||||||+|+ ||||| # ||+|| | +| | | | Sbjct 735 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYRG 783 |
| Mus musculus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 ||||||+ ||||+||||||+|+ ||||| # ||+|| | +| | | | Sbjct 738 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYRG 786 |
| rats, Peptide Partial, 723 aa | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 ||||||+ ||||+||||||+|+ ||||| # ||+|| | +| | | | Sbjct 674 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYRG 722 |
| Canis lupus familiaris | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 ||||||+ ||||+||||||+|+ ||||| # ||+|| | +| | | | Sbjct 735 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYRG 783 |
| Oryctolagus cuniculus | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 ||||||+ ||||+||||||+|+ ||||| # ||+|| | +| | | | Sbjct 739 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTNITYRG 787 |
| Biomphalaria glabrata | Query 757 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKY 795 ||| |||||||||+ |||||||#|||||| | +| || | Sbjct 747 IHDTREFAKFEKERQNAKWDTG#ENPIYKQATSTFKNPTY 785 |
| mice, Peptide Partial, 680 aa | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVN 792 ||||||+ ||||+||||||+|+ ||||| # ||+|| | +| | Sbjct 635 LIWKLLITIHDRKEFAKFEEERARAKWDTA#NNPLYKEATSTFTN 678 |
| Xenopus laevis | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 +|||++ | || |+ +||||+||+||+ |# ||+| +| ||| || + |+ Sbjct 723 IIWKIITEIKDRNEYQRFEKERMNSKWNPG#HNPLYHNATTTVQNPNFSGE 772 |
| Podocoryne carnea | Query 757 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 | ||||||||||++ | |||+|#|||||| | +| || | | Sbjct 740 IQDRREFAKFEKDRQNPKWDSG#ENPIYKKATSTFQNPMYGNK 781 |
| Caenorhabditis briggsae | Query 758 HDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||| |+||| |++ ||||| #|||||| | || || | || Sbjct 768 HDRAEYAKFNNERLMAKWDTN#ENPIYKQATTTFKNPVYAGK 808 |
| Ovis aries | Query 750 IWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 |||||+ |||+| |||| |+ ||| ||# ||+|+ + +| | |+ | Sbjct 728 IWKLLVSFHDRKEVAKFEAERSKAKWQTG#TNPLYRGSTSTFKNVTYKHK 776 |
| Caenorhabditis elegans | Query 758 HDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||| |+| | |++ ||||| #|||||| | || || | || Sbjct 767 HDRSEYATFNNERLMAKWDTN#ENPIYKQATTTFKNPVYAGK 807 |
| Mus sp. | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 | ++| + |+||||+ +||||+ | # ||+||||+|| |||+++| Sbjct 743 LAYRLSVEIYDRREYRRFEKEQQQLNWKQD#NNPLYKSAITTTVNPRFQG 791 |
| Strongylocentrotus purpuratus | Query 757 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||| ||||+ || |+ |#|||||| + + || | | Sbjct 765 IHDRREFQNFEKERANATWEGG#ENPIYKPSTSVFKNPTYNIK 806 |
| Lytechinus variegatus | Query 757 IHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEGK 798 ||||||| ||||+ || |+ |#|||||| + + || | | Sbjct 765 IHDRREFQNFEKERANATWEGG#ENPIYKPSTSVFKNPTYNIK 806 |
| Pan troglodytes | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYE 796 | ++| + |+||||+++||||+ | # ||+||||+|| +||+++ Sbjct 744 LAYRLSVEIYDRREYSRFEKEQQQLNWKQD#SNPLYKSAITTTINPRFQ 791 |
| Homo sapiens | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKY 795 +||| |+ + | ||+ +|||||+ ++|+ #+||++||| |||+|||+ Sbjct 721 VIWKALIHLSDLREYRRFEKEKLKSQWNN-#DNPLFKSATTTVMNPKF 766 |
| Ovis canadensis | Query 750 IWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKY 795 ||| | + | ||+ +|||||+ ++|+ #+||++||| |||+|||+ Sbjct 723 IWKALTHLSDLREYHRFEKEKLKSQWNN-#DNPLFKSATTTVMNPKF 767 |
| Sigmodon hispidus | Query 750 IWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKY 795 ||| | + | ||+ |||||+ ++|+ #+||++||| |||+|||+ Sbjct 722 IWKALTHLTDLREYRHFEKEKLKSQWNN-#DNPLFKSATTTVMNPKF 766 |
| Schistosoma japonicum | Query 751 WKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYE 796 +||++ | |||| | |+++ | +|+ #||||++| | |+|| +| Sbjct 239 YKLVITIDDRRELANFKQQGENMRWEMA#ENPIFESPTTNVLNPTFE 284 |
| Halocynthia roretzi | Query 749 LIWKLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 +|||++ + |+||+ ||+||+ || |#|||+| +| + || + | Sbjct 785 IIWKVIQTLRDKREYEKFKKEEDLRKWTKG#ENPVYVNASSKFDNPMFGG 833 |
| Acropora millepora | Query 752 KLLMIIHDRREFAKFEKEKMNAKWDTG#ENPIYKSAVTTVVNPKYEG 797 | | + || |+ |||+|+|++|| #+||+|++| || || | | Sbjct 744 KGLFTMVDRIEYQKFERERMHSKWTRE#KNPLYQAAKTTFENPTYAG 789 |
| Macaca mulatta | Query 755 MIIHDRREFAKFEKEKMNAKW 775 ||||||||||||||||||||| Query 755 MIIHDRREFAKFEKEKMNAKW 775 |
[Site 4] NPIYKSAVTT789-VVNPKYEGK
Thr789 Val
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Asn780 | Pro781 | Ile782 | Tyr783 | Lys784 | Ser785 | Ala786 | Val787 | Thr788 | Thr789 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Val790 | Val791 | Asn792 | Pro793 | Lys794 | Tyr795 | Glu796 | Gly797 | Lys798 | - |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| RREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Tetraodon nigroviridis | 89.00 | 5 | unnamed protein product |
| 2 | Xenopus laevis | 88.20 | 2 | integrin beta-1 subunit |
| 3 | N/A | 87.40 | 27 | ITB1_RAT Integrin beta-1 precursor (Fibronectin r |
| 4 | Mus musculus | 87.40 | 12 | Fn receptor beta prechain |
| 5 | Bos taurus | 87.00 | 7 | integrin beta 1 |
| 6 | Gallus gallus | 87.00 | 3 | integrin, beta 1 (fibronectin receptor, beta poly |
| 7 | Sus scrofa | 87.00 | 3 | integrin beta-1 subunit |
| 8 | Homo sapiens | 86.70 | 10 | ITB1_HUMAN Integrin beta-1 precursor (Fibronectin |
| 9 | Pongo pygmaeus | 86.70 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 10 | Danio rerio | 85.90 | 6 | integrin, beta 1a |
| 11 | Ictalurus punctatus | 85.50 | 2 | beta-1 integrin |
| 12 | Felis catus | 85.10 | 1 | integrin beta 1 |
| 13 | Oryctolagus cuniculus | 83.60 | 1 | integrin beta 1 |
| 14 | Drosophila melanogaster | 71.60 | 1 | myospheroid CG1560-PA |
| 15 | Anopheles gambiae str. PEST | 70.90 | 1 | integrin beta subunit (AGAP000815-PA) |
| 16 | Anopheles gambiae | 70.90 | 1 | integrin beta subunit |
| 17 | Pseudoplusia includens | 70.10 | 1 | integrin beta 1 |
| 18 | Canis familiaris | 65.10 | 10 | PREDICTED: similar to integrin beta 1 isoform 1D |
| 19 | Crassostrea gigas | 64.70 | 1 | integrin beta cgh |
| 20 | Biomphalaria glabrata | 62.80 | 1 | beta integrin subunit |
| 21 | Podocoryne carnea | 62.40 | 1 | AF308652_1 integrin beta chain |
| 22 | Gallus gallus | 60.50 | 2 | integrin beta 1A precursor |
| 23 | Xenopus laevis | 56.60 | 1 | hypothetical protein LOC379708 |
| 24 | Rattus norvegicus | 55.80 | 5 | integrin beta 3 |
| 25 | Oryctolagus cuniculus | 55.80 | 1 | glycoprotein IIIa |
| 26 | Mus musculus | 55.80 | 1 | integrin beta 3 precursor |
| 27 | Sus scrofa | 55.80 | 1 | integrin beta chain, beta 3 |
| 28 | rats, Peptide Partial, 723 aa | 55.80 | 1 | beta 3 integrin, GPIIIA |
| 29 | Canis lupus familiaris | 55.80 | 1 | integrin beta chain, beta 3 |
| 30 | Caenorhabditis elegans | 55.80 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 31 | synthetic construct | 55.50 | 3 | AF239959_1 hybrid integrin beta 3 subunit precurs |
| 32 | Caenorhabditis briggsae | 55.50 | 1 | Hypothetical protein CBG03601 |
| 33 | Mus sp. | 55.50 | 1 | beta 7 integrin |
| 34 | Strongylocentrotus purpuratus | 54.30 | 3 | integrin beta-C subunit |
| 35 | Lytechinus variegatus | 54.30 | 1 | beta-C integrin subunit |
| 36 | Pan troglodytes | 53.50 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 37 | mice, Peptide Partial, 680 aa | 52.40 | 1 | beta 3 integrin, GPIIIA |
| 38 | Ovis aries | 50.40 | 2 | antigen CD18 |
| 39 | Homo sapiens | 50.40 | 1 | integrin, beta 2 precursor |
| 40 | Ovis canadensis | 50.10 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 41 | Sigmodon hispidus | 48.90 | 1 | AF445415_1 integrin beta-2 precursor |
| 42 | Acropora millepora | 47.80 | 1 | integrin subunit betaCn1 |
| 43 | Schistosoma japonicum | 47.00 | 1 | SJCHGC06221 protein |
| 44 | Pacifastacus leniusculus | 45.40 | 1 | integrin |
| 45 | Halocynthia roretzi | 42.40 | 1 | integrin beta Hr2 precursor |
| 46 | Ophlitaspongia tenuis | 39.70 | 1 | integrin subunit betaPo1 |
| 47 | Cyprinus carpio | 38.50 | 1 | CD18 type 2 |
| 48 | Macaca mulatta | 37.70 | 1 | integrin beta 1 |
Top-ranked sequences
| organism | matching |
|---|---|
| Tetraodon nigroviridis | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Xenopus laevis | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| N/A | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Mus musculus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Bos taurus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Gallus gallus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Sus scrofa | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Homo sapiens | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Pongo pygmaeus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Danio rerio | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#|+||||||| Sbjct 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VINPKYEGK 798 |
| Ictalurus punctatus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||| ||||||||||||#||||||||| Sbjct 769 RREFAKFEKEKMNAKWDAGENPIYKSAVTT#VVNPKYEGK 807 |
| Felis catus | Query 761 REFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |||||||||||||||||||||||||||||#||||||||| Query 761 REFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Oryctolagus cuniculus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 ||||||||||||||||||||||||||||||#||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |
| Drosophila melanogaster | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |||||+||||+|||||||||||||| | +|# || | || Sbjct 808 RREFARFEKERMNAKWDTGENPIYKQATST#FKNPMYAGK 846 |
| Anopheles gambiae str. PEST | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |||||+||||+| |||||||||||| | ||# || | || Sbjct 799 RREFARFEKERMMAKWDTGENPIYKQATTT#FKNPTYAGK 837 |
| Anopheles gambiae | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |||||+||||+| |||||||||||| | ||# || | || Sbjct 799 RREFARFEKERMMAKWDTGENPIYKQATTT#FKNPTYAGK 837 |
| Pseudoplusia includens | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |||||+||||+| |||||||||||| | +|# || | || Sbjct 799 RREFARFEKERMMAKWDTGENPIYKQATST#FKNPTYAGK 837 |
| Canis familiaris | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |||||||||||||||||| ||||||| + # || | | Sbjct 783 RREFAKFEKEKMNAKWDTQENPIYKSPINN#FKNPNYGRK 821 |
| Crassostrea gigas | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795 +|| |+|||| |||+|||||||||| | +|# ||| | Sbjct 762 KRELARFEKEAMNARWDTGENPIYKQATST#FVNPTY 797 |
| Biomphalaria glabrata | Query 761 REFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795 |||||||||+ ||||||||||||| | +|# || | Sbjct 751 REFAKFEKERQNAKWDTGENPIYKQATST#FKNPTY 785 |
| Podocoryne carnea | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |||||||||++ | |||+||||||| | +|# || | | Sbjct 743 RREFAKFEKDRQNPKWDSGENPIYKKATST#FQNPMYGNK 781 |
| Gallus gallus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAV 787 |||||||||||||||||||||||||||| Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAV 787 |
| Xenopus laevis | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 | |+ +||||+||+||+ | ||+| +| ||#| || + |+ Sbjct 734 RNEYQRFEKERMNSKWNPGHNPLYHNATTT#VQNPNFSGE 772 |
| Rattus norvegicus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 |+||||||+|+ ||||| ||+|| | +|# | | | Sbjct 749 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYRG 786 |
| Oryctolagus cuniculus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 |+||||||+|+ ||||| ||+|| | +|# | | | Sbjct 750 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYRG 787 |
| Mus musculus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 |+||||||+|+ ||||| ||+|| | +|# | | | Sbjct 749 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYRG 786 |
| Sus scrofa | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 |+||||||+|+ ||||| ||+|| | +|# | | | Sbjct 746 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYRG 783 |
| rats, Peptide Partial, 723 aa | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 |+||||||+|+ ||||| ||+|| | +|# | | | Sbjct 685 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYRG 722 |
| Canis lupus familiaris | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 |+||||||+|+ ||||| ||+|| | +|# | | | Sbjct 746 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYRG 783 |
| Caenorhabditis elegans | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 | |+| | |++ ||||| |||||| | ||# || | || Sbjct 769 RSEYATFNNERLMAKWDTNENPIYKQATTT#FKNPVYAGK 807 |
| synthetic construct | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 |+||||||+|+ ||||| ||+|| | +|# | | | Sbjct 750 RKEFAKFEEERARAKWDTANNPLYKEATST#FTNITYRG 787 |
| Caenorhabditis briggsae | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 | |+||| |++ ||||| |||||| | ||# || | || Sbjct 770 RAEYAKFNNERLMAKWDTNENPIYKQATTT#FKNPVYAGK 808 |
| Mus sp. | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 |||+ +||||+ | ||+||||+||# |||+++| Sbjct 754 RREYRRFEKEQQQLNWKQDNNPLYKSAITT#TVNPRFQG 791 |
| Strongylocentrotus purpuratus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |||| ||||+ || |+ ||||||| + + # || | | Sbjct 768 RREFQNFEKERANATWEGGENPIYKPSTSV#FKNPTYNIK 806 |
| Lytechinus variegatus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEGK 798 |||| ||||+ || |+ ||||||| + + # || | | Sbjct 768 RREFQNFEKERANATWEGGENPIYKPSTSV#FKNPTYNIK 806 |
| Pan troglodytes | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYE 796 |||+++||||+ | ||+||||+||# +||+++ Sbjct 755 RREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQ 791 |
| mice, Peptide Partial, 680 aa | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVN 792 |+||||||+|+ ||||| ||+|| | +|# | Sbjct 646 RKEFAKFEEERARAKWDTANNPLYKEATST#FTN 678 |
| Ovis aries | Query 761 REFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795 ||+ +|||||+ ++|+ +||++||| ||#|+|||+ Sbjct 734 REYHRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 767 |
| Homo sapiens | Query 761 REFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795 ||+ +|||||+ ++|+ +||++||| ||#|+|||+ Sbjct 733 REYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 766 |
| Ovis canadensis | Query 761 REFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795 ||+ +|||||+ ++|+ +||++||| ||#|+|||+ Sbjct 734 REYHRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 767 |
| Sigmodon hispidus | Query 761 REFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795 ||+ |||||+ ++|+ +||++||| ||#|+|||+ Sbjct 733 REYRHFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 766 |
| Acropora millepora | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 | |+ |||+|+|++|| +||+|++| ||# || | | Sbjct 752 RIEYQKFERERMHSKWTREKNPLYQAAKTT#FENPTYAG 789 |
| Schistosoma japonicum | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYE 796 ||| | |+++ | +|+ ||||++| | #|+|| +| Sbjct 248 RRELANFKQQGENMRWEMAENPIFESPTTN#VLNPTFE 284 |
| Pacifastacus leniusculus | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795 |||+||||||+ |||+|||| ||# || + Sbjct 762 RREYAKFEKERKLPSGKRAENPLYKSAKTT#FQNPAF 797 |
| Halocynthia roretzi | Query 760 RREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 +||+ ||+||+ || ||||+| +| + # || + | Sbjct 796 KREYEKFKKEEDLRKWTKGENPVYVNASSK#FDNPMFGG 833 |
| Ophlitaspongia tenuis | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795 | |||+| |||+ |||+|+|| # || | Sbjct 803 EVRKFEREIKNAKYTKNENPLYRSATKD#YQNPLY 836 |
| Cyprinus carpio | Query 761 REFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKYEG 797 ||+ +|||++ + | +| ||++++| ||#| || + | Sbjct 730 REWKRFEKDRKHEK-TSGTNPLFQNATTT#VQNPTFSG 765 |
| Macaca mulatta | Query 760 RREFAKFEKEKMNAKW 775 |||||||||||||||| Query 760 RREFAKFEKEKMNAKW 775 |
[Site 5] IYKSAVTTVV791-NPKYEGK
Val791 Asn
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ile782 | Tyr783 | Lys784 | Ser785 | Ala786 | Val787 | Thr788 | Thr789 | Val790 | Val791 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Asn792 | Pro793 | Lys794 | Tyr795 | Glu796 | Gly797 | Lys798 | - | - | - |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| EFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Tetraodon nigroviridis | 84.70 | 5 | unnamed protein product |
| 2 | Xenopus laevis | 82.80 | 2 | integrin beta-1 subunit |
| 3 | N/A | 82.40 | 27 | ITB1_RAT Integrin beta-1 precursor (Fibronectin r |
| 4 | Mus musculus | 82.40 | 12 | integrin beta 1 (fibronectin receptor beta) |
| 5 | Sus scrofa | 82.00 | 3 | integrin beta-1 subunit |
| 6 | Gallus gallus | 82.00 | 3 | integrin, beta 1 (fibronectin receptor, beta poly |
| 7 | Felis catus | 82.00 | 1 | integrin beta 1 |
| 8 | Homo sapiens | 81.60 | 10 | ITB1_HUMAN Integrin beta-1 precursor (Fibronectin |
| 9 | Bos taurus | 81.60 | 7 | integrin beta 1 |
| 10 | Pongo pygmaeus | 81.60 | 1 | ITB1_PONPY Integrin beta-1 precursor (Fibronectin |
| 11 | Danio rerio | 81.30 | 6 | integrin, beta 1a |
| 12 | Ictalurus punctatus | 80.10 | 2 | beta-1 integrin |
| 13 | Oryctolagus cuniculus | 79.00 | 1 | integrin beta 1 |
| 14 | Drosophila melanogaster | 67.00 | 1 | myospheroid CG1560-PA |
| 15 | Anopheles gambiae str. PEST | 66.60 | 1 | integrin beta subunit (AGAP000815-PA) |
| 16 | Anopheles gambiae | 66.60 | 1 | integrin beta subunit |
| 17 | Pseudoplusia includens | 65.50 | 1 | integrin beta 1 |
| 18 | Crassostrea gigas | 61.20 | 1 | integrin beta cgh |
| 19 | Canis familiaris | 60.50 | 10 | PREDICTED: similar to integrin beta 1 isoform 1D |
| 20 | Biomphalaria glabrata | 60.10 | 1 | beta integrin subunit |
| 21 | Podocoryne carnea | 57.80 | 1 | AF308652_1 integrin beta chain |
| 22 | Gallus gallus | 56.20 | 2 | integrin beta 1A precursor |
| 23 | Caenorhabditis briggsae | 55.80 | 1 | Hypothetical protein CBG03601 |
| 24 | Xenopus laevis | 54.30 | 1 | hypothetical protein LOC379708 |
| 25 | Caenorhabditis elegans | 53.50 | 1 | Paralysed Arrest at Two-fold family member (pat-3 |
| 26 | Rattus norvegicus | 52.80 | 5 | integrin beta 3 |
| 27 | Mus musculus | 52.80 | 1 | integrin beta 3 precursor |
| 28 | Sus scrofa | 52.80 | 1 | integrin beta chain, beta 3 |
| 29 | rats, Peptide Partial, 723 aa | 52.80 | 1 | beta 3 integrin, GPIIIA |
| 30 | Canis lupus familiaris | 52.80 | 1 | integrin beta chain, beta 3 |
| 31 | Oryctolagus cuniculus | 52.80 | 1 | glycoprotein IIIa |
| 32 | synthetic construct | 52.40 | 3 | AF239959_1 hybrid integrin beta 3 subunit precurs |
| 33 | Mus sp. | 50.80 | 1 | beta 7 integrin |
| 34 | Strongylocentrotus purpuratus | 49.70 | 3 | integrin beta-C subunit |
| 35 | Lytechinus variegatus | 49.70 | 1 | beta-C integrin subunit |
| 36 | mice, Peptide Partial, 680 aa | 49.30 | 1 | beta 3 integrin, GPIIIA |
| 37 | Pan troglodytes | 48.90 | 2 | PREDICTED: integrin, beta 7 isoform 5 |
| 38 | Ovis aries | 48.10 | 2 | antigen CD18 |
| 39 | Homo sapiens | 48.10 | 1 | integrin, beta 2 precursor |
| 40 | Ovis canadensis | 48.10 | 1 | ITB2_OVICA Integrin beta-2 precursor (Cell surfac |
| 41 | Sigmodon hispidus | 46.60 | 1 | AF445415_1 integrin beta-2 precursor |
| 42 | Acropora millepora | 46.60 | 1 | integrin subunit betaCn1 |
| 43 | Schistosoma japonicum | 42.40 | 1 | SJCHGC06221 protein |
| 44 | Pacifastacus leniusculus | 40.80 | 1 | integrin |
| 45 | Ophlitaspongia tenuis | 39.70 | 1 | integrin subunit betaPo1 |
| 46 | Halocynthia roretzi | 38.90 | 1 | integrin beta Hr2 precursor |
| 47 | Cyprinus carpio | 35.80 | 2 | integrin beta2-chain |
| 48 | Geodia cydonium | 35.40 | 1 | integrin beta subunit |
| 49 | Suberites domuncula | 34.70 | 1 | integrin beta subunit |
| 50 | Macaca mulatta | 33.10 | 1 | integrin beta 1 |
Top-ranked sequences
| organism | matching |
|---|---|
| Tetraodon nigroviridis | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Xenopus laevis | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| N/A | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Mus musculus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Sus scrofa | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Gallus gallus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Felis catus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Homo sapiens | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Bos taurus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Pongo pygmaeus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Danio rerio | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |||||||||||||||||||||||||||||+#||||||| Sbjct 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVI#NPKYEGK 798 |
| Ictalurus punctatus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||| ||||||||||||||#||||||| Sbjct 771 EFAKFEKEKMNAKWDAGENPIYKSAVTTVV#NPKYEGK 807 |
| Oryctolagus cuniculus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 ||||||||||||||||||||||||||||||#||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |
| Drosophila melanogaster | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |||+||||+|||||||||||||| | +| #|| | || Sbjct 810 EFARFEKERMNAKWDTGENPIYKQATSTFK#NPMYAGK 846 |
| Anopheles gambiae str. PEST | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |||+||||+| |||||||||||| | || #|| | || Sbjct 801 EFARFEKERMMAKWDTGENPIYKQATTTFK#NPTYAGK 837 |
| Anopheles gambiae | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |||+||||+| |||||||||||| | || #|| | || Sbjct 801 EFARFEKERMMAKWDTGENPIYKQATTTFK#NPTYAGK 837 |
| Pseudoplusia includens | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |||+||||+| |||||||||||| | +| #|| | || Sbjct 801 EFARFEKERMMAKWDTGENPIYKQATSTFK#NPTYAGK 837 |
| Crassostrea gigas | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 | |+|||| |||+|||||||||| | +| |#|| | Sbjct 764 ELARFEKEAMNARWDTGENPIYKQATSTFV#NPTY 797 |
| Canis familiaris | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |||||||||||||||| ||||||| + #|| | | Sbjct 785 EFAKFEKEKMNAKWDTQENPIYKSPINNFK#NPNYGRK 821 |
| Biomphalaria glabrata | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 ||||||||+ ||||||||||||| | +| #|| | Sbjct 752 EFAKFEKERQNAKWDTGENPIYKQATSTFK#NPTY 785 |
| Podocoryne carnea | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |||||||++ | |||+||||||| | +| #|| | | Sbjct 745 EFAKFEKDRQNPKWDSGENPIYKKATSTFQ#NPMYGNK 781 |
| Gallus gallus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAV 787 |||||||||||||||||||||||||| Query 762 EFAKFEKEKMNAKWDTGENPIYKSAV 787 |
| Caenorhabditis briggsae | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |+||| |++ ||||| |||||| | || #|| | || Sbjct 772 EYAKFNNERLMAKWDTNENPIYKQATTTFK#NPVYAGK 808 |
| Xenopus laevis | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |+ +||||+||+||+ | ||+| +| ||| #|| + |+ Sbjct 736 EYQRFEKERMNSKWNPGHNPLYHNATTTVQ#NPNFSGE 772 |
| Caenorhabditis elegans | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 |+| | |++ ||||| |||||| | || #|| | || Sbjct 771 EYATFNNERLMAKWDTNENPIYKQATTTFK#NPVYAGK 807 |
| Rattus norvegicus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 ||||||+|+ ||||| ||+|| | +| #| | | Sbjct 751 EFAKFEEERARAKWDTANNPLYKEATSTFT#NITYRG 786 |
| Mus musculus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 ||||||+|+ ||||| ||+|| | +| #| | | Sbjct 751 EFAKFEEERARAKWDTANNPLYKEATSTFT#NITYRG 786 |
| Sus scrofa | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 ||||||+|+ ||||| ||+|| | +| #| | | Sbjct 748 EFAKFEEERARAKWDTANNPLYKEATSTFT#NITYRG 783 |
| rats, Peptide Partial, 723 aa | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 ||||||+|+ ||||| ||+|| | +| #| | | Sbjct 687 EFAKFEEERARAKWDTANNPLYKEATSTFT#NITYRG 722 |
| Canis lupus familiaris | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 ||||||+|+ ||||| ||+|| | +| #| | | Sbjct 748 EFAKFEEERARAKWDTANNPLYKEATSTFT#NITYRG 783 |
| Oryctolagus cuniculus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 ||||||+|+ ||||| ||+|| | +| #| | | Sbjct 752 EFAKFEEERARAKWDTANNPLYKEATSTFT#NITYRG 787 |
| synthetic construct | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 ||||||+|+ ||||| ||+|| | +| #| | | Sbjct 752 EFAKFEEERARAKWDTANNPLYKEATSTFT#NITYRG 787 |
| Mus sp. | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 |+ +||||+ | ||+||||+|| |#||+++| Sbjct 756 EYRRFEKEQQQLNWKQDNNPLYKSAITTTV#NPRFQG 791 |
| Strongylocentrotus purpuratus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 || ||||+ || |+ ||||||| + + #|| | | Sbjct 770 EFQNFEKERANATWEGGENPIYKPSTSVFK#NPTYNIK 806 |
| Lytechinus variegatus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEGK 798 || ||||+ || |+ ||||||| + + #|| | | Sbjct 770 EFQNFEKERANATWEGGENPIYKPSTSVFK#NPTYNIK 806 |
| mice, Peptide Partial, 680 aa | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#N 792 ||||||+|+ ||||| ||+|| | +| #| Sbjct 648 EFAKFEEERARAKWDTANNPLYKEATSTFT#N 678 |
| Pan troglodytes | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYE 796 |+++||||+ | ||+||||+|| +#||+++ Sbjct 757 EYSRFEKEQQQLNWKQDSNPLYKSAITTTI#NPRFQ 791 |
| Ovis aries | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 |+ +|||||+ ++|+ +||++||| |||+#|||+ Sbjct 735 EYHRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 |
| Homo sapiens | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 |+ +|||||+ ++|+ +||++||| |||+#|||+ Sbjct 734 EYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 766 |
| Ovis canadensis | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 |+ +|||||+ ++|+ +||++||| |||+#|||+ Sbjct 735 EYHRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 |
| Sigmodon hispidus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 |+ |||||+ ++|+ +||++||| |||+#|||+ Sbjct 734 EYRHFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 766 |
| Acropora millepora | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 |+ |||+|+|++|| +||+|++| || #|| | | Sbjct 754 EYQKFERERMHSKWTREKNPLYQAAKTTFE#NPTYAG 789 |
| Schistosoma japonicum | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYE 796 | | |+++ | +|+ ||||++| | |+#|| +| Sbjct 250 ELANFKQQGENMRWEMAENPIFESPTTNVL#NPTFE 284 |
| Pacifastacus leniusculus | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 |+||||||+ |||+|||| || #|| + Sbjct 764 EYAKFEKERKLPSGKRAENPLYKSAKTTFQ#NPAF 797 |
| Ophlitaspongia tenuis | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 | |||+| |||+ |||+|+|| #|| | Sbjct 803 EVRKFEREIKNAKYTKNENPLYRSATKDYQ#NPLY 836 |
| Halocynthia roretzi | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 |+ ||+||+ || ||||+| +| + #|| + | Sbjct 798 EYEKFKKEEDLRKWTKGENPVYVNASSKFD#NPMFGG 833 |
| Cyprinus carpio | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKYEG 797 |+ +|||++ + | +| ||++++| ||+ #|| + | Sbjct 732 EWKRFEKDRKHEK-TSGTNPLFQNATTTIQ#NPTFSG 766 |
| Geodia cydonium | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 | ||| | |+ |||+| || | #|| | Sbjct 843 ELKKFENELAKVKYTKNENPLYHSATTEHK#NPIY 876 |
| Suberites domuncula | Query 762 EFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795 | ||||| |+ +||+|+|| #|| | Sbjct 729 EVKKFEKELAKTKYPKHQNPLYRSAAKDYQ#NPIY 762 |
| Macaca mulatta | Query 762 EFAKFEKEKMNAKW 775 |||||||||||||| Query 762 EFAKFEKEKMNAKW 775 |
* References
[PubMed ID: 24510996] Lee C, Lee C, Lee S, Siu A, Ramos DM, The cytoplasmic extension of the integrin beta6 subunit regulates epithelial-to-mesenchymal transition. Anticancer Res. 2014 Feb;34(2):659-64.
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