SB0089 : Protein kinase C[gamma]
[ CaMP Format ]
* Basic Information
| Organism | Rattus norvegicus (Norway rat) |
| Protein Names | protein kinase C gamma type [Rattus norvegicus]; protein kinase C gamma type; protein kinase C type I (gamma type); PKC-gamma; Protein kinase C gamma type; 2.7.11.13 |
| Gene Names | Prkcg; Pkcc, Pkcg, Prkcc; Pkcc; Pkcg; Prkcc; protein kinase C, gamma |
| Gene Locus | 1q12; chromosome 1 |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 697 aa
Average Mass: 78.357 kDa
Monoisotopic Mass: 78.307 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Putative zinc-RING and/or ribbon 1. | 47 | 86 | 156.0 | 5.5 |
| Putative zinc-RING and/or ribbon 2. | 113 | 150 | 157.0 | 5.1 |
| C2 domain 1. | 173 | 277 | 3.0 | 0.0 |
| --- cleavage 321 --- | ||||
| --- cleavage 338 --- | ||||
| Phosphotransferase enzyme family 1. | 472 | 502 | 164.0 | 0.0 |
| Protein kinase C terminal domain 1. | 551 | 557 | 18.0 | 0.0 |
| Protein kinase C terminal domain 2. | 642 | 678 | 9.0 | 0.2 |
3. Sequence Information
Fasta Sequence: SB0089.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
* Cleavage Information
2 [sites] cleaved by Calpain 1 and 2
Source Reference: [PubMed ID: 2537303] Kishimoto A, Mikawa K, Hashimoto K, Yasuda I, Tanaka S, Tominaga M, Kuroda T, Nishizuka Y, Limited proteolysis of protein kinase C subspecies by calcium-dependent neutral protease (calpain). J Biol Chem. 1989 Mar 5;264(7):4088-92.
Cleavage sites (±10aa)
[Site 1] YERVRMGPSS321-SPIPSPSPSP
Ser321 
Ser
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Tyr312 | Glu313 | Arg314 | Val315 | Arg316 | Met317 | Gly318 | Pro319 | Ser320 | Ser321 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser322 | Pro323 | Ile324 | Pro325 | Ser326 | Pro327 | Ser328 | Pro329 | Ser330 | Pro331 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| DADNCSLLQKFEACNYPLELYERVRMGPSSSPIPSPSPSPTDSKRCFFGASPGRLHISDF |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 126.00 | 2 | protein kinase C, gamma |
| 2 | Oryctolagus cuniculus | 126.00 | 1 | protein kinase C, gamma |
| 3 | Homo sapiens | 125.00 | 2 | protein kinase C gamma |
| 4 | N/A | 122.00 | 2 | KPCG_BOVIN Protein kinase C gamma type (PKC-gamma) |
| 5 | Canis familiaris | 67.80 | 1 | PREDICTED: similar to Protein kinase C, gamma typ |
| 6 | Caenorhabditis elegans | 32.30 | 1 | B0412.3 |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 292 DADNCSLLQKFEACNYPLELYERVRMGPSS#SPIPSPSPSPTDSKRCFFGASPGRLHISDF 351 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 292 DADNCSLLQKFEACNYPLELYERVRMGPSS#SPIPSPSPSPTDSKRCFFGASPGRLHISDF 351 |
| Oryctolagus cuniculus | Query 292 DADNCSLLQKFEACNYPLELYERVRMGPSS#SPIPSPSPSPTDSKRCFFGASPGRLHISDF 351 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 292 DADNCSLLQKFEACNYPLELYERVRMGPSS#SPIPSPSPSPTDSKRCFFGASPGRLHISDF 351 |
| Homo sapiens | Query 292 DADNCSLLQKFEACNYPLELYERVRMGPSS#SPIPSPSPSPTDSKRCFFGASPGRLHISDF 351 ||||||||||||||||||||||||||||||#|||||||||||| ||||||||||||||||| Sbjct 131 DADNCSLLQKFEACNYPLELYERVRMGPSS#SPIPSPSPSPTDPKRCFFGASPGRLHISDF 190 |
| N/A | Query 292 DADNCSLLQKFEACNYPLELYERVRMGPSS#SPIPSPSPSPTDSKRCFFGASPGRLHISDF 351 |||||+||||||||||||||||||| ||||#|||||||||||||||||||||||||||||| Sbjct 277 DADNCNLLQKFEACNYPLELYERVRTGPSS#SPIPSPSPSPTDSKRCFFGASPGRLHISDF 336 |
| Canis familiaris | Query 292 DADNCSLLQKFEACNYPLELYERVRMGPSS#SPIPSPSPSPTDSKRCFFGASPGRLHISDF 351 |||||||||||| ||||||||#||||||||||||||||||| |||||||||| Sbjct 278 DADNCSLLQKFE----------RVRMGPSS#SPIPSPSPSPTDSKRCFFGTSPGRLHISDF 327 |
| Caenorhabditis elegans | Query 316 RMGPSS#SPIPSPSPSPTDSKRCFFGASPGRLH 347 | | +# | ||| | | ||| | |++ Sbjct 385 RNAPQN#VPYPSPDPLANSSSTVFFGQRPWRIN 416 |
[Site 2] PSPTDSKRCF338-FGASPGRLHI
Phe338 Phe
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Pro329 | Ser330 | Pro331 | Thr332 | Asp333 | Ser334 | Lys335 | Arg336 | Cys337 | Phe338 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Phe339 | Gly340 | Ala341 | Ser342 | Pro343 | Gly344 | Arg345 | Leu346 | His347 | Ile348 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LELYERVRMGPSSSPIPSPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKGSFGKVMLA |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 122.00 | 16 | protein kinase C, gamma |
| 2 | Oryctolagus cuniculus | 122.00 | 5 | protein kinase C, gamma |
| 3 | Homo sapiens | 120.00 | 13 | protein kinase C gamma |
| 4 | N/A | 119.00 | 15 | KPCG_BOVIN Protein kinase C gamma type (PKC-gamma) |
| 5 | Canis familiaris | 87.00 | 15 | PREDICTED: similar to Protein kinase C, gamma typ |
| 6 | Petromyzon marinus | 53.50 | 1 | protein kinase C |
| 7 | Homo sapiens | 51.20 | 2 | aging-associated gene 6 protein |
| 8 | synthetic construct | 51.20 | 1 | protein kinase C alpha |
| 9 | Rattus rattus | 51.20 | 1 | KPCA_RAT Protein kinase C alpha type (PKC-alpha) |
| 10 | Danio rerio | 50.80 | 3 | protein kinase C |
| 11 | Bos taurus | 50.40 | 3 | protein kinase C, alpha |
| 12 | Danio rerio | 50.40 | 2 | protein kinase C, beta 1, like |
| 13 | Scyliorhinus canicula | 49.70 | 1 | protein kinase C |
| 14 | Tetraodon nigroviridis | 49.30 | 4 | unnamed protein product |
| 15 | Caenorhabditis elegans | 45.10 | 3 | Protein Kinase C family member (pkc-1) |
| 16 | Xenopus tropicalis | 45.10 | 1 | protein kinase C, delta |
| 17 | Rattus norvegicus | 43.90 | 5 | unnamed protein product |
| 18 | Branchiostoma lanceolatum | 43.50 | 1 | protein kinase C |
| 19 | Caenorhabditis briggsae AF16 | 43.10 | 1 | Hypothetical protein CBG23354 |
| 20 | Takifugu rubripes | 43.10 | 1 | protein kinase C, alpha type |
| 21 | Squalus acanthias | 42.70 | 2 | s-sgk2 |
| 22 | Myxine glutinosa | 42.70 | 1 | protein kinase C |
| 23 | Drosophila pseudoobscura | 42.40 | 1 | GA15149-PA |
| 24 | Drosophila melanogaster | 42.40 | 1 | Protein C kinase 98E CG1954-PA |
| 25 | Schizosaccharomyces pombe | 42.00 | 2 | protein kinase |
| 26 | Neurospora crassa OR74A | 42.00 | 1 | hypothetical protein NCU06544 |
| 27 | Schizosaccharomyces pombe 972h- | 42.00 | 1 | protein kinase C (PKC)-like Pck2 |
| 28 | Neurospora crassa | 42.00 | 1 | protein kinase C homologue |
| 29 | Ancylostoma caninum | 41.60 | 1 | AF301263_1 protein kinase C |
| 30 | Drosophila melanogaster | 41.20 | 1 | GH13631p |
| 31 | Xenopus laevis | 41.20 | 1 | protein kinase-delta1 |
| 32 | Bombyx mori | 40.80 | 1 | conventional protein kinase C |
| 33 | Sycon raphanus | 40.40 | 2 | Serine/Threonine protein kinase |
| 34 | Sporothrix schenckii | 39.70 | 1 | AF124792_1 protein kinase C; serine/threonine pro |
| 35 | Caenorhabditis elegans | 39.30 | 2 | protein kinase C2 B isoform |
| 36 | Apis mellifera | 39.30 | 1 | PREDICTED: similar to protein kinase C, delta |
| 37 | Rattus norvegicus | 39.30 | 1 | protein kinase C, epsilon |
| 38 | Chaetomium globosum CBS 148.51 | 39.30 | 1 | conserved hypothetical protein |
| 39 | synthetic construct | 38.90 | 4 | serum/glucocorticoid regulated kinase |
| 40 | Leptosphaeria maculans | 38.90 | 1 | AF487263_9 protein kinase C |
| 41 | Candida albicans SC5314 | 38.90 | 1 | protein kinase C |
| 42 | Oryctolagus cuniculus | 38.90 | 1 | serum/glucocorticoid regulated kinase |
| 43 | Gallus gallus | 38.50 | 1 | serum/glucocorticoid regulated kinase 1 |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 309 LELYERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 309 LELYERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 |
| Oryctolagus cuniculus | Query 309 LELYERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 309 LELYERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 |
| Homo sapiens | Query 309 LELYERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 ||||||||||||||||||||||||| ||||#|||||||||||||||||||||||||||||| Sbjct 148 LELYERVRMGPSSSPIPSPSPSPTDPKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 207 |
| N/A | Query 309 LELYERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 |||||||| |||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 294 LELYERVRTGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 353 |
| Canis familiaris | Query 309 LELYERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 |+ +||||||||||||||||||||||||||#|| ||||||||||||||||||||||||||| Sbjct 285 LQKFERVRMGPSSSPIPSPSPSPTDSKRCF#FGTSPGRLHISDFSFLMVLGKGSFGKVMLA 344 |
| Petromyzon marinus | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|+ |+||| | | # |+ |+ ||+|||||||||||||||| Sbjct 235 FEKARLGPSVKPRASDERRANSLSAIL#NNANVDRVKADDFNFLMVLGKGSFGKVMLA 291 |
| Homo sapiens | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|+ ++||+ + + ||| | |+ # + |+ ++||+|||||||||||||||| Sbjct 305 FEKAKLGPAGNKVISPS---EDRKQP-#-SNNLDRVKLTDFNFLMVLGKGSFGKVMLA 356 |
| synthetic construct | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|+ ++||+ + + ||| | |+ # + |+ ++||+|||||||||||||||| Sbjct 305 FEKAKLGPAGNKVISPS---EDRKQP-#-SNNLDRVKLTDFNFLMVLGKGSFGKVMLA 356 |
| Rattus rattus | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|+ ++||+ + + ||| | |+ # + |+ ++||+|||||||||||||||| Sbjct 305 FEKAKLGPAGNKVISPS---EDRKQP-#-SNNLDRVKLTDFNFLMVLGKGSFGKVMLA 356 |
| Danio rerio | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|| ++||| + | | || #+| + |+ +|||+|||||||||||||||| Sbjct 236 FERAKIGPSKT---DGSSSNAISKFDS#YG-NRDRMKLSDFNFLMVLGKGSFGKVMLA 288 |
| Bos taurus | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|+ ++||+ + + ||| # |+ ++||+|||||||||||||||| Sbjct 305 FEKAKLGPAGNKVISPSEDRRQPSNNL#-----DRVKLTDFNFLMVLGKGSFGKVMLA 356 |
| Danio rerio | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|| ++|| ++ + | | + # + |+ ++||+|+|||||||||||||| Sbjct 301 FERAKIGPGTNN--TDGASKNDLSKYD#ANGNQDRMKLADFNFIMVLGKGSFGKVMLA 355 |
| Scyliorhinus canicula | Query 312 YERVRMGPSSSPIP---SPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|| |+|| | | | | |+ # + |+ ++||+|||||||||||||||| Sbjct 226 FERARIGPGSKAAEEKRSSSWSKIDN----#--GNRDRMKLADFNFLMVLGKGSFGKVMLA 279 |
| Tetraodon nigroviridis | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|| ++|| + + | + | # + |+ ++||+|||||||||||||||| Sbjct 241 FERAKIGPGKN---TDGKSANAASRFD#SNGNQDRMKLADFNFLMVLGKGSFGKVMLA 294 |
| Caenorhabditis elegans | Query 326 SPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 | | | | | # | | | ||+|+ ||||||||||||| Sbjct 353 SEDDSGTTSSRSA#SKVPGGTLSIHDFTFMKVLGKGSFGKVMLA 395 |
| Xenopus tropicalis | Query 317 MGPSSSPIPSPSPSPTDSKRCF#FGASP-------GRLHISDFSFLMVLGKGSFGKVMLA 368 + | + +| | + | +# |+|| || | +| | ||||||||||+|| Sbjct 97 VNPKTPGLPMPDATDNQYDRLW#EGSSPHPHISLSSRLKIDNFVFHKVLGKGSFGKVLLA 155 |
| Rattus norvegicus | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|| ++| + | + | || # | + |+ ++||+|||||||||||||||+ Sbjct 305 FERAKIGQGTKA-PEEKTANTISKFDN#NG-NRDRMKLTDFNFLMVLGKGSFGKVMLS 359 |
| Branchiostoma lanceolatum | Query 334 SKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 |+ | # | | + +||+|||||||||||||||| Sbjct 251 SEECN#IG-SLDHMKAADFNFLMVLGKGSFGKVMLA 284 |
| Caenorhabditis briggsae AF16 | Query 344 GRLHISDFSFLMVLGKGSFGKVMLA 368 | | |+||+|+ ||||||||||||| Sbjct 372 GTLSINDFTFMKVLGKGSFGKVMLA 396 |
| Takifugu rubripes | Query 312 YERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPG---RLHISDFSFLMVLGKGSFGKVMLA 368 +|+ ++| | +|+| +| #| | |+ ++||+|| +|||||||||||| Sbjct 302 FEKAKLGQGKKVI-----TPSDHRR--#FSLPSGNMDRVRLNDFNFLALLGKGSFGKVMLA 354 |
| Squalus acanthias | Query 326 SPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 || |||| ++ # +| + |||+ | |+||||||||+|| Sbjct 236 SPPPSPTTAQINL#GPSSNPQAKPSDFNLLKVIGKGSFGKVLLA 278 |
| Myxine glutinosa | Query 309 LELYERVR---MGPSSSPIPSPSP-SPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGK 364 ||| +|++ + | ||+ |+|| # + |+++ || || ||||||||| Sbjct 219 LELRQRLQRSQIARSDKNKQSPAKDQPSDSASL-#--SGLDRVNLEDFVFLTVLGKGSFGK 275 Query 365 VMLA 368 |||| Query 365 VMLA 368 |
| Drosophila pseudoobscura | Query 343 PGRLHISDFSFLMVLGKGSFGKVMLA 368 ||+ + ||+|+ ||||||||||||| Sbjct 396 PGKCSLLDFNFIKVLGKGSFGKVMLA 421 |
| Drosophila melanogaster | Query 343 PGRLHISDFSFLMVLGKGSFGKVMLA 368 ||+ + ||+|+ ||||||||||||| Sbjct 400 PGKCSLLDFNFIKVLGKGSFGKVMLA 425 |
| Schizosaccharomyces pombe | Query 319 PSSSPIPSPSPSPTDSKRCF---#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 || + | | |+ # |+ + ||+|| |||||+||||||| Sbjct 648 PSLDAVKEPIPVPSVETSVVAQD#LTHKAKRIGLEDFTFLSVLGKGNFGKVMLA 700 |
| Neurospora crassa OR74A | Query 319 PSSSPIPSPSPSPTDSKRCF#FGASPG---RLHISDFSFLMVLGKGSFGKVMLA 368 ||+| +| |+ | | # || |+ + |+|| |||||+||||||| Sbjct 787 PSASGVPVPTKKPLPS----#-ATDPGTGMRIGLDHFNFLAVLGKGNFGKVMLA 834 |
| Schizosaccharomyces pombe 972h- | Query 319 PSSSPIPSPSPSPTDSKRCF---#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 || + | | |+ # |+ + ||+|| |||||+||||||| Sbjct 648 PSLDAVKEPIPVPSVETSVVAQD#LTHKAKRIGLEDFTFLSVLGKGNFGKVMLA 700 |
| Neurospora crassa | Query 319 PSSSPIPSPSPSPTDSKRCF#FGASPG---RLHISDFSFLMVLGKGSFGKVMLA 368 ||+| +| |+ | | # || |+ + |+|| |||||+||||||| Sbjct 787 PSASGVPVPTKKPLPS----#-ATDPGTGMRIGLDHFNFLAVLGKGNFGKVMLA 834 |
| Ancylostoma caninum | Query 330 SPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKV 365 | |||| # || + |||+|+ |||||||||| Sbjct 10 STTDSKHSL#SGAQSQIVKESDFTFITVLGKGSFGKV 45 |
| Drosophila melanogaster | Query 343 PGRLHISDFSFLMVLGKGSFGKVMLA 368 ||+ + ||+|+ ||||||||||||| Sbjct 215 PGKCSLLDFNFIKVLGKGSFGKVMLA 240 |
| Xenopus laevis | Query 317 MGPSSSPIPSPSPSPTDSKRCF#FGASP-------GRLHISDFSFLMVLGKGSFGKVMLA 368 +|| +| |+ + +# | +| || | +| | ||||||||||+|| Sbjct 315 VGPKVPGLPVPNAPDNQYDKLW#EGITPHPHISLSSRLKIDNFIFHKVLGKGSFGKVLLA 373 |
| Bombyx mori | Query 341 ASPGRLHISDFSFLMVLGKGSFGKVMLA 368 |+ + +||+|+|||||||||||||| Sbjct 330 AAADVIRATDFNFIMVLGKGSFGKVMLA 357 |
| Sycon raphanus | Query 341 ASPGRLHISDFSFLMVLGKGSFGKVMLA 368 || | +||| | ||||||||||||| Sbjct 387 ASSKRYTLSDFHLLKVLGKGSFGKVMLA 414 |
| Sporothrix schenckii | Query 324 IPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 + | || || # + |+ + +|+|| |||||+||||||| Sbjct 848 VKKPLPSATDP----#--GTGQRIGLDNFNFLAVLGKGNFGKVMLA 886 |
| Caenorhabditis elegans | Query 320 SSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +|| | +| | # ++ + |||+|| ||||||||||+| Sbjct 317 NSSSKPKDPAAPRASTLPL#GSSNHNVIKASDFNFLTVLGKGSFGKVLLG 365 |
| Apis mellifera | Query 345 RLHISDFSFLMVLGKGSFGKVMLA 368 + +++||+|| ||||||||||+|| Sbjct 296 KYNVTDFNFLKVLGKGSFGKVLLA 319 |
| Rattus norvegicus | Query 341 ASPG-----------RLHISDFSFLMVLGKGSFGKVMLA 368 |||| || + +|+|+ ||||||||||||| Sbjct 387 ASPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLA 425 |
| Chaetomium globosum CBS 148.51 | Query 318 GPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 ||+ |+|| + | # |+ + |+|| |||||+||||||| Sbjct 786 GPTKKPLPSATDPGTGQ----#------RIGLDHFNFLAVLGKGNFGKVMLA 826 |
| synthetic construct | Query 313 ERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +++ +||||+| || # || || |+||||||||+|| Sbjct 81 QQINLGPSSNPHAKPS----------#-----------DFHFLKVIGKGSFGKVLLA 115 |
| Leptosphaeria maculans | Query 313 ERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 | + | | +| +| + # | |+ + |+|| |||||+||||||| Sbjct 822 EAIAQIPPSKQLPPANPENKVTPSAN#TQGSGKRIGLDHFNFLAVLGKGNFGKVMLA 877 |
| Candida albicans SC5314 | Query 339 FGASPGR---LHISDFSFLMVLGKGSFGKVMLA 368 || | | + + || || |||||+||||||| Sbjct 755 FGKSKRRKRKVGLDDFQFLAVLGKGNFGKVMLA 787 |
| Oryctolagus cuniculus | Query 313 ERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +++ +||||+| || # || || |+||||||||+|| Sbjct 81 QQINLGPSSNPHAKPS----------#-----------DFHFLKVIGKGSFGKVLLA 115 |
| Gallus gallus | Query 313 ERVRMGPSSSPIPSPSPSPTDSKRCF#FGASPGRLHISDFSFLMVLGKGSFGKVMLA 368 +++ +||||+| || # || || |+||||||||+|| Sbjct 82 QQINLGPSSNPHAKPS----------#-----------DFHFLKVIGKGSFGKVLLA 116 |
* References
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[PubMed ID: 22126757] ... Zhu QW, Wang H, Zhang JY, Ye P, Luo LM, [Effect of pioglitazone on hypoxia/reoxygenation injury and protein kinase C expression in neonatal rat cardiomyocytes]. Nan Fang Yi Ke Da Xue Xue Bao. 2011 Nov;31(11):1819-23.
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[PubMed ID: 9287082] ... Krugers HJ, Douma BR, Andringa G, Bohus B, Korf J, Luiten PG, Exposure to chronic psychosocial stress and corticosterone in the rat: effects on spatial discrimination learning and hippocampal protein kinase Cgamma immunoreactivity. Hippocampus. 1997;7(4):427-36.
[PubMed ID: 2246272] ... Chen KH, Widen SG, Wilson SH, Huang KP, Characterization of the 5'-flanking region of the rat protein kinase C gamma gene. J Biol Chem. 1990 Nov 15;265(32):19961-5.
[PubMed ID: 3387228] ... Ono Y, Fujii T, Igarashi K, Kikkawa U, Ogita K, Nishizuka Y, Nucleotide sequences of cDNAs for alpha and gamma subspecies of rat brain protein kinase C. Nucleic Acids Res. 1988 Jun 10;16(11):5199-200.
[PubMed ID: 3755379] ... Knopf JL, Lee MH, Sultzman LA, Kriz RW, Loomis CR, Hewick RM, Bell RM, Cloning and expression of multiple protein kinase C cDNAs. Cell. 1986 Aug 15;46(4):491-502.