SB0121 : Calcineurin
[ CaMP Format ]
* Basic Information
| Organism | Rattus norvegicus (Norway rat) |
| Protein Names | serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [Rattus norvegicus]; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; CAM-PRP catalytic subunit; calmodulin-dependent calcineurin A subunit alpha isoform; Calcineurin subunit A alpha; protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform; protein phosphatase 3, catalytic subunit, alpha isoform; protein phosphatase-2Ba; Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; 3.1.3.16; Calmodulin-dependent calcineurin A subunit alpha isoform |
| Gene Names | Ppp3ca; Calna; protein phosphatase 3, catalytic subunit, alpha isozyme |
| Gene Locus | 2q43; chromosome 2 |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 521 aa
Average Mass: 58.643 kDa
Monoisotopic Mass: 58.606 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Calcineurin-like phosphoesterase 1. | 84 | 284 | 2.0 | 0.0 |
3. Sequence Information
Fasta Sequence: SB0121.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Known Structures in PDB: 4IL1 (X-ray; 300 A; A/B/C/D=1-492)
* Cleavage Information
4 [sites] cleaved by Calpain 2
Source Reference: [PubMed ID: 14627704] Wu HY, Tomizawa K, Oda Y, Wei FY, Lu YF, Matsushita M, Li ST, Moriwaki A, Matsui H, Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration. J Biol Chem. 2004 Feb 6;279(6):4929-40. Epub 2003 Nov 19.
Cleavage sites (±10aa)
[Site 1] VLREESESVL421-TLKGLTPTGM
Leu421 
Thr
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Val412 | Leu413 | Arg414 | Glu415 | Glu416 | Ser417 | Glu418 | Ser419 | Val420 | Leu421 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr422 | Leu423 | Lys424 | Gly425 | Leu426 | Thr427 | Pro428 | Thr429 | Gly430 | Met431 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| RKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEA |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 121.00 | 14 | calcineurin |
| 2 | Homo sapiens | 121.00 | 6 | protein phosphatase 3, catalytic subunit, alpha i |
| 3 | Rattus norvegicus | 121.00 | 3 | protein phosphatase 3, catalytic subunit, alpha i |
| 4 | Xenopus laevis | 121.00 | 2 | protein phosphatase 3, catalytic subunit, alpha i |
| 5 | Bos taurus | 121.00 | 2 | protein phosphatase 3, catalytic subunit, alpha i |
| 6 | Mus musculus | 119.00 | 6 | protein phosphatase 3, catalytic subunit, beta is |
| 7 | Canis familiaris | 119.00 | 5 | PREDICTED: similar to protein phosphatase 3, cata |
| 8 | Canis familiaris | 119.00 | 5 | PREDICTED: similar to protein phosphatase 3 (form |
| 9 | Oryctolagus cuniculus | 119.00 | 2 | protein phosphatase 3 (formerly 2B), catalytic su |
| 10 | Sus scrofa | 114.00 | 1 | protein phosphatase 3, catalytic subunit, alpha i |
| 11 | Gallus gallus | 114.00 | 1 | calcineurin A alpha |
| 12 | Macaca mulatta | 114.00 | 1 | PREDICTED: protein phosphatase 3 (formerly 2B), c |
| 13 | Xenopus laevis | 114.00 | 1 | calcineurin catalytic subunit |
| 14 | Tetraodon nigroviridis | 113.00 | 4 | unnamed protein product |
| 15 | Pan troglodytes | 110.00 | 1 | PREDICTED: protein phosphatase 3 (formerly 2B), c |
| 16 | Drosophila melanogaster | 100.00 | 3 | Protein phosphatase 2B at 14D CG9842-PA |
| 17 | Drosophila pseudoobscura | 100.00 | 1 | GA22069-PA |
| 18 | Mizuhopecten yessoensis | 97.40 | 1 | calcineurin A |
| 19 | Bombyx mori | 95.90 | 1 | calcineurin A |
| 20 | Drosophila melanogaster | 94.00 | 1 | Calcineurin A1 CG1455-PA |
| 21 | Schistosoma japonicum | 93.60 | 1 | SJCHGC09435 protein |
| 22 | Schistosoma mansoni | 93.20 | 1 | calcineurin A |
| 23 | Caenorhabditis elegans | 90.10 | 2 | abnormal CHEmotaxis family member (tax-6) |
| 24 | Caenorhabditis briggsae AF16 | 89.40 | 1 | Hypothetical protein CBG08362 |
| 25 | Filobasidiella neoformans | 63.90 | 1 | AF159511_1 calcineurin A catalytic subunit |
| 26 | Cryptococcus neoformans var. neoformans JEC21 | 63.50 | 1 | calcineurin A catalytic subunit |
| 27 | Schizosaccharomyces pombe | 62.40 | 1 | protein phosphatase 2B |
| 28 | Schizosaccharomyces pombe 972h- | 62.40 | 1 | calcineurin catalytic subunit Ppb1 |
| 29 | Cryptococcus gattii | 59.70 | 1 | calcineurin A catalytic subunit |
| 30 | Dictyostelium discoideum AX4 | 58.90 | 1 | calcineurin A |
| 31 | Dictyostelium discoideum | 58.90 | 1 | calcineurin A |
| 32 | Gibberella zeae PH-1 | 57.00 | 1 | P2B_NEUCR SERINE/THREONINE PROTEIN PHOSPHATASE 2B |
| 33 | Cryptosporidium parvum Iowa II | 56.60 | 1 | protein phosphatase 2B catalytic subunit, calcine |
| 34 | Cryptosporidium hominis TU502 | 56.60 | 1 | protein phosphatase 2b |
| 35 | Candida glabrata | 55.80 | 1 | unnamed protein product |
| 36 | Yarrowia lipolytica | 55.10 | 2 | hypothetical protein |
| 37 | Aspergillus oryzae | 54.30 | 1 | calcineurin A |
| 38 | Neurospora crassa | 54.30 | 1 | phosphoprotein phosphatase 3-alpha catalytic chai |
| 39 | Aspergillus oryzae RIB40 | 54.30 | 1 | hypothetical protein |
| 40 | Aspergillus parasiticus | 54.30 | 1 | calcineurin A |
| 41 | Chaetomium globosum CBS 148.51 | 54.30 | 1 | serine/threonine protein phosphatase 2B catalytic |
| 42 | Paramecium tetraurelia strain d4-2 | 53.90 | 8 | hypothetical protein GSPATT00033854001 |
| 43 | Candida albicans SC5314 | 53.50 | 2 | hypothetical protein CaO19_13454 |
| 44 | Plasmodium falciparum 3D7 | 53.10 | 1 | protein phosphatase, putative |
| 45 | Aspergillus nidulans FGSC A4 | 52.80 | 1 | P2B_EMENI SERINE/THREONINE PROTEIN PHOSPHATASE 2B |
| 46 | Plasmodium chabaudi chabaudi | 52.40 | 1 | protein phosphatase |
| 47 | Plasmodium yoelii yoelii str. 17XNL | 52.40 | 1 | protein phosphatase 2B |
| 48 | Aspergillus fumigatus Af293 | 52.40 | 1 | calcineurin catalytic subunit CnaA |
| 49 | Toxoplasma gondii | 51.60 | 1 | protein phosphatase 2B catalytic subunit |
| 50 | Ashbya gossypii ATCC 10895 | 51.60 | 1 | AER118Cp |
| 51 | Saccharomyces cerevisiae | 51.20 | 2 | phosphatase 2Bw catalytic subunit |
| 52 | Exophiala dermatitidis | 51.20 | 1 | calcineurin |
| 53 | Plasmodium berghei strain ANKA | 50.10 | 1 | protein phosphatase |
| 54 | Paramecium tetraurelia | 49.70 | 4 | calcineurin-A5-2 |
| 55 | Ustilago maydis 521 | 49.30 | 1 | hypothetical protein UM00936.1 |
| 56 | Ustilago maydis | 49.30 | 1 | calcineurin catalytic subunit; Ucn1 |
| 57 | Paramecium tetraurelia | 47.40 | 1 | protein phosphatase 2B |
| 58 | Dictyostelium discoideum AX4 | 43.50 | 1 | hypothetical protein DDBDRAFT_0205063 |
| 59 | Tetrahymena thermophila SB210 | 36.20 | 1 | Ser/Thr protein phosphatase family protein |
| 60 | mice, Ehrlich ascites tumor cells, Peptide Partial, 96 aa | 34.30 | 1 | calcium/calmodulin-dependent protein phosphatase |
| 61 | mice, Ehrlich ascites tumor cells, Peptide Partial, 97 aa | 33.90 | 1 | calcium/calmodulin-dependent protein phosphatase |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |
| Homo sapiens | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |
| Rattus norvegicus | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |
| Xenopus laevis | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |
| Bos taurus | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |
| Mus musculus | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |||+||||||||||||||||||||||||||#||||||||||||||||+||+|||||||||| Sbjct 402 RKEIIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLAGGRQTLQSATVEA 461 |
| Canis familiaris | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |||+||||||||||||||||||||||||||#||||||||||||||||+||+|||||||||| Sbjct 398 RKEIIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLAGGRQTLQSATVEA 457 |
| Canis familiaris | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |||+||||||||||||||||||||||||||#||||||||||||||||+||+|||||||||| Sbjct 401 RKEIIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLAGGRQTLQSATVEA 460 |
| Oryctolagus cuniculus | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |||+||||||||||||||||||||||||||#||||||||||||||||+||+|||||||||| Sbjct 401 RKEIIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLAGGRQTLQSATVEA 460 |
| Sus scrofa | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||| Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Gallus gallus | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||| Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Macaca mulatta | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||| Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Xenopus laevis | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||| Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Tetraodon nigroviridis | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |||||+||||||||||++|||||||||+||#|||||||||||||||||||+|||||||+|| Sbjct 447 RKEVIKNKIRAIGKMAKMFSVLREESENVL#TLKGLTPTGMLPSGVLSGGRQTLQSATIEA 506 |
| Pan troglodytes | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |||+||||||||||||||||||||||||||#||||||||||||||||+||+||||| Sbjct 419 RKEIIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLAGGRQTLQSG 474 |
| Drosophila melanogaster | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||# |||||||| || | ||||||+|++| Sbjct 460 RKEVIRNKIRAIGKMARVFSVLREESESVL#QLKGLTPTGALPLGALSGGKQSLKNA 515 |
| Drosophila pseudoobscura | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||# |||||||| || | ||||||+|++| Sbjct 387 RKEVIRNKIRAIGKMARVFSVLREESESVL#QLKGLTPTGALPLGALSGGKQSLKNA 442 |
| Mizuhopecten yessoensis | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |||||+|||||||||||||+||||||||||# |||||| |+|| | ||||| || || Sbjct 392 RKEVIKNKIRAIGKMARVFTVLREESESVL#QLKGLTPNGLLPLGALSGGKDTLTSA 447 |
| Bombyx mori | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |||||||||||||||| |||||||||||||# |||||||| || | ||||| +|++| Sbjct 389 RKEVIRNKIRAIGKMAHVFSVLREESESVL#QLKGLTPTGALPLGALSGGKTSLKNA 444 |
| Drosophila melanogaster | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |||+|||||||||||+||||+|||||||||# |||||||| || | ||||+ +|+ | Sbjct 460 RKEIIRNKIRAIGKMSRVFSILREESESVL#QLKGLTPTGALPVGALSGGRDSLKEA 515 |
| Schistosoma japonicum | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||| |+||||||||| # |||||| |||| | |||||++| | Sbjct 113 RKEVIRNKIRAIGKMARTFTVLREESESVF#ELKGLTPNGMLPLGALSGGKESLNKA 168 |
| Schistosoma mansoni | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSAT 448 ||+||||||||||||||||+|||||||++|# ||||||||||| | |+||++ +++ + Sbjct 388 RKDVIRNKIRAIGKMARVFTVLREESETIL#ELKGLTPTGMLPLGALAGGREAIKAVS 444 |
| Caenorhabditis elegans | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 ||||||+|||||||||| ||||||||||||# |||||||| || | | || + ++ |+ Sbjct 418 RKEVIRHKIRAIGKMARAFSVLREESESVL#ALKGLTPTGALPMGTLQGGSRGVREVAAES 477 |
| Caenorhabditis briggsae AF16 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQ 445 ||||||+|||||||||| ||||||||||||# |||||||| ||+| | || + ++ Sbjct 399 RKEVIRHKIRAIGKMARAFSVLREESESVL#ALKGLTPTGALPAGTLQGGSRGIR 452 |
| Filobasidiella neoformans | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |+++|+||| |+|+|+||||+|||||| | # || ++ + ||+|+|+ | + ++ | Sbjct 430 RRQIIKNKILAVGRMSRVFSLLREESERVS#ELKSISGSNALPAGMLASGAEGIKEA 485 |
| Cryptococcus neoformans var. neoformans JEC21 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |+++|+||| |+|+|+||||+|||||| | # || ++ + ||+|+|+ | + ++ | Sbjct 417 RRQIIKNKILAVGRMSRVFSLLREESERVS#ELKSISGSNALPAGMLASGAEGIKEA 472 |
| Schizosaccharomyces pombe | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |+++|+||| |||+++||||||||| ||| # || ++ | ||+| | | + +++| Sbjct 440 RRQIIKNKIMAIGRISRVFSVLREERESVS#ELKNVSGTQRLPAGTLMLGAEGIKNA 495 |
| Schizosaccharomyces pombe 972h- | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |+++|+||| |||+++||||||||| ||| # || ++ | ||+| | | + +++| Sbjct 440 RRQIIKNKIMAIGRISRVFSVLREERESVS#ELKNVSGTQRLPAGTLMLGAEGIKNA 495 |
| Cryptococcus gattii | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGG----KQTLQ 445 |+++|+||| |+|+|+||||+|||||| | # || + + ||+|+|+ | |+|+| Sbjct 73 RRQIIKNKILAVGRMSRVFSLLREESERVS#ELKSIAGSNALPAGMLASGAEGIKETIQ 130 |
| Dictyostelium discoideum AX4 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |++++| |++++ || |+||+||+| |+++# +| +|+ +| |+|+ || |+ | Sbjct 444 RRQMLRAKVKSVSKMMRMFSLLRQERETIM#MIKSFSPSRKIPQGLLTEGKDALKKA 499 |
| Dictyostelium discoideum | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |++++| |++++ || |+||+||+| |+++# +| +|+ +| |+|+ || |+ | Sbjct 444 RRQMLRAKVKSVSKMMRMFSLLRQERETIM#MIKSFSPSRKIPQGLLTEGKDALKKA 499 |
| Gibberella zeae PH-1 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |+ |+||| |||+++||| ||||||| | # || ++ | ||+| | | + |++| Sbjct 402 RRRAIKNKILAIGRLSRVFQVLREESEKVT#ELKTVS-GGRLPAGTLMLGAEGLKNA 456 |
| Cryptosporidium parvum Iowa II | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQS 446 | + +| |++++ ++ |||| |||++| ++# |||+|| +| |+| ||+ |++ Sbjct 430 RADTLRKKVQSVARIMRVFSTLREQNELIV#KLKGVTPGHRIPMGLLLGGRDALEN 484 |
| Cryptosporidium hominis TU502 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQS 446 | + +| |++++ ++ |||| |||++| ++# |||+|| +| |+| ||+ |++ Sbjct 278 RADTLRKKVQSVARIMRVFSTLREQNELIV#KLKGVTPGHRIPMGLLLGGRDALEN 332 |
| Candida glabrata | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTL 444 |++ +|||| || |++|++|||||||+ | # || + +|+|| | |+ | | | Sbjct 477 RRKTLRNKILAIAKVSRMYSVLREESDKVQ#YLKSMN-SGILPRGALAHGSQGL 528 |
| Yarrowia lipolytica | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ +|||| |||+|+|+|+|||+||||| # || ++ | || | | | | ++ | Sbjct 439 QRRALRNKILAIGQMSRLFNVLRQESESVS#ELKAVS-GGKLPQGTLMLGGQGIRDA 493 |
| Aspergillus oryzae | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ |+||| |||+++||| ||||||| | # || | | ||+| | | + ++ | Sbjct 402 KRRAIKNKILAIGRLSRVFQVLREESERVT#ELKTAT-GGRLPAGTLMLGAEGIKQA 456 |
| Neurospora crassa | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ |+||| |||+++||| ||||||| | # || ++ | ||+| | | + +++| Sbjct 405 KRRAIKNKILAIGRLSRVFQVLREESERVT#ELKTVS-GGRLPAGTLMLGAEGIKNA 459 |
| Aspergillus oryzae RIB40 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ |+||| |||+++||| ||||||| | # || | | ||+| | | + ++ | Sbjct 427 KRRAIKNKILAIGRLSRVFQVLREESERVT#ELKTAT-GGRLPAGTLMLGAEGIKQA 481 |
| Aspergillus parasiticus | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ |+||| |||+++||| ||||||| | # || | | ||+| | | + ++ | Sbjct 403 KRRAIKNKILAIGRLSRVFQVLREESERVT#ELKTAT-GGRLPAGTLMLGAEGIKQA 457 |
| Chaetomium globosum CBS 148.51 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ |+||| |||+++||| ||||||| | # || ++ | ||+| | | + +++| Sbjct 408 KRRAIKNKILAIGRLSRVFQVLREESERVT#ELKTVS-GGRLPAGTLMLGAEGIKNA 462 |
| Paramecium tetraurelia strain d4-2 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVE 450 | ++||++ + | ++ ||||||||+# ||| | || |+|| || + | + Sbjct 411 EKLKNKLKFVATMMKLQKTLREESESVM#KLKGACPDKRLPKGILSAGKTAISDALAD 467 |
| Candida albicans SC5314 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQS 446 +|+ +|||| |||||+|+| ||||| |+| # || | | || | | | |++ Sbjct 496 KKQALRNKIIAIGKMSRMFQVLREEQENVA#HLKELN-RGSLPKGSLLHGADGLKN 549 |
| Plasmodium falciparum 3D7 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQS 446 | + +| |++++|++ ||| ||+|+| ++# ||| +| +| |+| ||+ |++ Sbjct 528 RTDTLRKKVQSVGRLMRVFRTLRKENELIV#QLKGCSPGYRIPVGLLLSGKEGLEN 582 |
| Aspergillus nidulans FGSC A4 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ |+||| |||+++||| ||||||| | # || | ||+| | | + ++ | Sbjct 405 KRRAIKNKILAIGRLSRVFQVLREESERVT#ELK-TAAGGRLPAGTLMLGAEGIKQA 459 |
| Plasmodium chabaudi chabaudi | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQS 446 + + +| |+++||++ ||| ||+|+| ++# ||| +| +| |+| ||+ |++ Sbjct 456 KADALRKKVQSIGRLMRVFRTLRKENELIV#QLKGCSPGYKIPVGLLLSGKEGLEN 510 |
| Plasmodium yoelii yoelii str. 17XNL | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQS 446 + + +| |+++||++ ||| ||+|+| ++# ||| +| +| |+| ||+ |++ Sbjct 447 KADALRKKVQSIGRLMRVFRTLRKENELIV#QLKGCSPGYKIPVGLLLSGKEGLEN 501 |
| Aspergillus fumigatus Af293 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ |+||| |||+++||| ||||||| | # || | ||+| | | + ++ | Sbjct 426 KRRAIKNKILAIGRLSRVFQVLREESERVT#ELK-TAAGGRLPAGTLMLGAEGIKQA 480 |
| Toxoplasma gondii | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQ 442 | + +| |++++|++ ||| ||+|+| ++# ||| || +| |+| |++ Sbjct 421 RADALRKKVQSVGRLMRVFKTLRQENELIV#RLKGCTPGHRIPVGLLLQGRE 471 |
| Ashbya gossypii ATCC 10895 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ +|+|| || |++|++|||||||+ | # || + +|+|| | || | + | | Sbjct 482 KRRALRSKILAIAKVSRMYSVLREESDKVQ#YLKTMN-SGVLPRGALSRGSEGLNEA 536 |
| Saccharomyces cerevisiae | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 |++ +|||| |+ |++|++||||||+ | # || +|+|| | || | + | | Sbjct 402 RRKALRNKILAVAKVSRMYSVLREETNKVQ#FLKDHN-SGVLPRGALSNGVKGLDEA 456 |
| Exophiala dermatitidis | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ |+||| |||+++||| ||||||+ | # || | ||+| | | + ++ | Sbjct 425 KRRAIKNKILAIGRLSRVFQVLREESQRVT#ELK-TQAGGRLPAGTLMLGAEGIKQA 479 |
| Plasmodium berghei strain ANKA | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQS 446 + + +| |+++||++ ||| ||+|+| ++# ||| +| +| |+| |++ |++ Sbjct 455 KADALRKKVQSIGRLMRVFRTLRKENELIV#QLKGCSPGYKIPVGLLLRGRKGLEN 509 |
| Paramecium tetraurelia | Query 394 EVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVE 450 | +++|++ + | ++ |||+|||++# ||| | || |+|| || + | + Sbjct 414 EKLKSKLKFVATMMKMQKTLREQSESIM#KLKGACPDKRLPKGILSAGKTAITDALAD 470 |
| Ustilago maydis 521 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVL 437 |+ +|+||| |+|+|+|||++||||+| | # || + | || | | Sbjct 434 RRTLIKNKILAVGRMSRVFALLREEAERVS#ELKS-SQTAKLPYGSL 478 |
| Ustilago maydis | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVL 437 |+ +|+||| |+|+|+|||++||||+| | # || + | || | | Sbjct 434 RRTLIKNKILAVGRMSRVFALLREEAERVS#ELKS-SQTAKLPYGSL 478 |
| Paramecium tetraurelia | Query 394 EVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATVE 450 | ++ || + | ++ |||+|||++# ||| | || |||+ || + | + Sbjct 412 EKLKKKIIFVANMIKMQKTLREQSESII#YLKGACPDKRLPRGVLTAGKSAIMDALAD 468 |
| Dictyostelium discoideum AX4 | Query 392 RKEVIRNKIRAIGKMARVFSVLREESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSA 447 +++++| ++++ || |+||+||+| |+++# +| + + + |+|+ || |+ | Sbjct 69 KRQLLRANVKSVSKM-RMFSLLRQEHETIM#MIKSFSASRKITQGLLTEGKDALKKA 123 |
| Tetrahymena thermophila SB210 | Query 414 REESESVL#TLKGLTPTGMLPSGVLSGGKQTLQSATV 449 |||||++|# ||| | +| |+|| | ++ | Sbjct 477 REESETIL#QLKGQCPDKRIPKGLLSSGVSAIKDNRV 512 |
| mice, Ehrlich ascites tumor cells, Peptide Partial, 96 aa | Query 392 RKEVIRNKIRAIGKM 406 ||||||||||||||| Query 392 RKEVIRNKIRAIGKM 406 |
| mice, Ehrlich ascites tumor cells, Peptide Partial, 97 aa | Query 392 RKEVIRNKIRAIGKM 406 |||+||||||||||| Sbjct 83 RKEIIRNKIRAIGKM 97 |
[Site 2] LREESESVLT422-LKGLTPTGML
Thr422 Leu
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Leu413 | Arg414 | Glu415 | Glu416 | Ser417 | Glu418 | Ser419 | Val420 | Leu421 | Thr422 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Leu423 | Lys424 | Gly425 | Leu426 | Thr427 | Pro428 | Thr429 | Gly430 | Met431 | Leu432 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| KEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAI |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 121.00 | 14 | calcineurin |
| 2 | Homo sapiens | 121.00 | 6 | protein phosphatase 3, catalytic subunit, alpha i |
| 3 | Rattus norvegicus | 121.00 | 3 | protein phosphatase 3, catalytic subunit, alpha i |
| 4 | Xenopus laevis | 121.00 | 2 | protein phosphatase 3, catalytic subunit, alpha i |
| 5 | Bos taurus | 121.00 | 2 | protein phosphatase 3, catalytic subunit, alpha i |
| 6 | Mus musculus | 118.00 | 6 | protein phosphatase 3, catalytic subunit, beta is |
| 7 | Canis familiaris | 118.00 | 5 | PREDICTED: similar to protein phosphatase 3 (form |
| 8 | Canis familiaris | 118.00 | 5 | PREDICTED: similar to protein phosphatase 3, cata |
| 9 | Oryctolagus cuniculus | 118.00 | 2 | protein phosphatase 3 (formerly 2B), catalytic su |
| 10 | Tetraodon nigroviridis | 113.00 | 4 | unnamed protein product |
| 11 | Sus scrofa | 112.00 | 1 | protein phosphatase 3, catalytic subunit, alpha i |
| 12 | Gallus gallus | 112.00 | 1 | calcineurin A alpha |
| 13 | Xenopus laevis | 112.00 | 1 | calcineurin catalytic subunit |
| 14 | Macaca mulatta | 112.00 | 1 | PREDICTED: protein phosphatase 3 (formerly 2B), c |
| 15 | Pan troglodytes | 108.00 | 1 | PREDICTED: protein phosphatase 3 (formerly 2B), c |
| 16 | Drosophila melanogaster | 98.60 | 3 | Protein phosphatase 2B at 14D CG9842-PA |
| 17 | Drosophila pseudoobscura | 98.60 | 1 | GA22069-PA |
| 18 | Mizuhopecten yessoensis | 95.10 | 1 | calcineurin A |
| 19 | Bombyx mori | 93.60 | 1 | calcineurin A |
| 20 | Drosophila melanogaster | 92.00 | 1 | Calcineurin A1 CG1455-PA |
| 21 | Schistosoma japonicum | 91.70 | 1 | SJCHGC09435 protein |
| 22 | Schistosoma mansoni | 91.30 | 1 | calcineurin A |
| 23 | Caenorhabditis elegans | 87.80 | 2 | abnormal CHEmotaxis family member (tax-6) |
| 24 | Caenorhabditis briggsae AF16 | 87.00 | 1 | Hypothetical protein CBG08362 |
| 25 | Filobasidiella neoformans | 62.00 | 1 | AF159511_1 calcineurin A catalytic subunit |
| 26 | Cryptococcus neoformans var. neoformans JEC21 | 61.60 | 1 | calcineurin A catalytic subunit |
| 27 | Schizosaccharomyces pombe 972h- | 60.10 | 1 | calcineurin catalytic subunit Ppb1 |
| 28 | Schizosaccharomyces pombe | 60.10 | 1 | protein phosphatase 2B |
| 29 | Cryptococcus gattii | 57.80 | 1 | calcineurin A catalytic subunit |
| 30 | Dictyostelium discoideum AX4 | 56.60 | 1 | calcineurin A |
| 31 | Dictyostelium discoideum | 56.60 | 1 | calcineurin A |
| 32 | Yarrowia lipolytica | 54.70 | 2 | hypothetical protein |
| 33 | Gibberella zeae PH-1 | 54.70 | 1 | P2B_NEUCR SERINE/THREONINE PROTEIN PHOSPHATASE 2B |
| 34 | Cryptosporidium parvum Iowa II | 54.70 | 1 | protein phosphatase 2B catalytic subunit, calcine |
| 35 | Cryptosporidium hominis TU502 | 54.70 | 1 | protein phosphatase 2b |
| 36 | Paramecium tetraurelia strain d4-2 | 53.90 | 7 | hypothetical protein GSPATT00033854001 |
| 37 | Candida glabrata | 53.50 | 1 | unnamed protein product |
| 38 | Chaetomium globosum CBS 148.51 | 53.50 | 1 | serine/threonine protein phosphatase 2B catalytic |
| 39 | Aspergillus oryzae RIB40 | 53.50 | 1 | hypothetical protein |
| 40 | Aspergillus oryzae | 53.50 | 1 | calcineurin A |
| 41 | Aspergillus parasiticus | 53.50 | 1 | calcineurin A |
| 42 | Neurospora crassa | 53.50 | 1 | phosphoprotein phosphatase 3-alpha catalytic chai |
| 43 | Candida albicans SC5314 | 52.80 | 2 | hypothetical protein CaO19_6033 |
| 44 | Aspergillus nidulans FGSC A4 | 52.00 | 1 | P2B_EMENI SERINE/THREONINE PROTEIN PHOSPHATASE 2B |
| 45 | Aspergillus fumigatus Af293 | 52.00 | 1 | calcineurin catalytic subunit CnaA |
| 46 | Plasmodium yoelii yoelii str. 17XNL | 51.60 | 1 | protein phosphatase 2B |
| 47 | Plasmodium chabaudi chabaudi | 51.60 | 1 | protein phosphatase |
| 48 | Plasmodium falciparum 3D7 | 51.20 | 1 | protein phosphatase, putative |
| 49 | Ashbya gossypii ATCC 10895 | 51.20 | 1 | AER118Cp |
| 50 | Exophiala dermatitidis | 50.40 | 1 | calcineurin |
| 51 | Paramecium tetraurelia | 49.70 | 4 | calcineurin-A5-2 |
| 52 | Plasmodium berghei strain ANKA | 49.70 | 1 | protein phosphatase |
| 53 | Toxoplasma gondii | 49.70 | 1 | protein phosphatase 2B catalytic subunit |
| 54 | Saccharomyces cerevisiae | 48.90 | 2 | phosphatase 2Bw catalytic subunit |
| 55 | Paramecium tetraurelia | 47.40 | 1 | protein phosphatase 2B |
| 56 | Ustilago maydis | 47.00 | 1 | calcineurin catalytic subunit; Ucn1 |
| 57 | Ustilago maydis 521 | 47.00 | 1 | hypothetical protein UM00936.1 |
| 58 | Dictyostelium discoideum AX4 | 42.70 | 1 | hypothetical protein DDBDRAFT_0205063 |
| 59 | Tetrahymena thermophila SB210 | 36.20 | 1 | Ser/Thr protein phosphatase family protein |
| 60 | mice, Ehrlich ascites tumor cells, Peptide Partial, 96 aa | 32.00 | 1 | calcium/calmodulin-dependent protein phosphatase |
| 61 | mice, Ehrlich ascites tumor cells, Peptide Partial, 97 aa | 31.60 | 1 | calcium/calmodulin-dependent protein phosphatase |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 |
| Homo sapiens | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 |
| Rattus norvegicus | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 |
| Xenopus laevis | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 |
| Bos taurus | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 |
| Mus musculus | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||+|||||||||||||||||||||||||||#|||||||||||||||+||+||||||||||| Sbjct 403 KEIIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLAGGRQTLQSATVEAI 462 |
| Canis familiaris | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||+|||||||||||||||||||||||||||#|||||||||||||||+||+||||||||||| Sbjct 402 KEIIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLAGGRQTLQSATVEAI 461 |
| Canis familiaris | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||+|||||||||||||||||||||||||||#|||||||||||||||+||+||||||||||| Sbjct 399 KEIIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLAGGRQTLQSATVEAI 458 |
| Oryctolagus cuniculus | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||+|||||||||||||||||||||||||||#|||||||||||||||+||+||||||||||| Sbjct 402 KEIIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLAGGRQTLQSATVEAI 461 |
| Tetraodon nigroviridis | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEAI 452 ||||+||||||||||++|||||||||+|||#||||||||||||||||||+|||||||+||| Sbjct 448 KEVIKNKIRAIGKMAKMFSVLREESENVLT#LKGLTPTGMLPSGVLSGGRQTLQSATIEAI 507 |
| Sus scrofa | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||| Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Gallus gallus | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||| Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Xenopus laevis | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||| Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Macaca mulatta | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||| Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Pan troglodytes | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||+|||||||||||||||||||||||||||#|||||||||||||||+||+||||| Sbjct 420 KEIIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLAGGRQTLQSG 474 |
| Drosophila melanogaster | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||| #|||||||| || | ||||||+|++| Sbjct 461 KEVIRNKIRAIGKMARVFSVLREESESVLQ#LKGLTPTGALPLGALSGGKQSLKNA 515 |
| Drosophila pseudoobscura | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||| #|||||||| || | ||||||+|++| Sbjct 388 KEVIRNKIRAIGKMARVFSVLREESESVLQ#LKGLTPTGALPLGALSGGKQSLKNA 442 |
| Mizuhopecten yessoensis | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||+|||||||||||||+|||||||||| #|||||| |+|| | ||||| || || Sbjct 393 KEVIKNKIRAIGKMARVFTVLREESESVLQ#LKGLTPNGLLPLGALSGGKDTLTSA 447 |
| Bombyx mori | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||| ||||||||||||| #|||||||| || | ||||| +|++| Sbjct 390 KEVIRNKIRAIGKMAHVFSVLREESESVLQ#LKGLTPTGALPLGALSGGKTSLKNA 444 |
| Drosophila melanogaster | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ||+|||||||||||+||||+||||||||| #|||||||| || | ||||+ +|+ | Sbjct 461 KEIIRNKIRAIGKMSRVFSILREESESVLQ#LKGLTPTGALPVGALSGGRDSLKEA 515 |
| Schistosoma japonicum | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 |||||||||||||||| |+||||||||| #|||||| |||| | |||||++| | Sbjct 114 KEVIRNKIRAIGKMARTFTVLREESESVFE#LKGLTPNGMLPLGALSGGKESLNKA 168 |
| Schistosoma mansoni | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSAT 448 |+||||||||||||||||+|||||||++| #||||||||||| | |+||++ +++ + Sbjct 389 KDVIRNKIRAIGKMARVFTVLREESETILE#LKGLTPTGMLPLGALAGGREAIKAVS 444 |
| Caenorhabditis elegans | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVEA 451 |||||+|||||||||| |||||||||||| #|||||||| || | | || + ++ |+ Sbjct 419 KEVIRHKIRAIGKMARAFSVLREESESVLA#LKGLTPTGALPMGTLQGGSRGVREVAAES 477 |
| Caenorhabditis briggsae AF16 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQ 445 |||||+|||||||||| |||||||||||| #|||||||| ||+| | || + ++ Sbjct 400 KEVIRHKIRAIGKMARAFSVLREESESVLA#LKGLTPTGALPAGTLQGGSRGIR 452 |
| Filobasidiella neoformans | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 +++|+||| |+|+|+||||+|||||| | #|| ++ + ||+|+|+ | + ++ | Sbjct 431 RQIIKNKILAVGRMSRVFSLLREESERVSE#LKSISGSNALPAGMLASGAEGIKEA 485 |
| Cryptococcus neoformans var. neoformans JEC21 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 +++|+||| |+|+|+||||+|||||| | #|| ++ + ||+|+|+ | + ++ | Sbjct 418 RQIIKNKILAVGRMSRVFSLLREESERVSE#LKSISGSNALPAGMLASGAEGIKEA 472 |
| Schizosaccharomyces pombe 972h- | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 +++|+||| |||+++||||||||| ||| #|| ++ | ||+| | | + +++| Sbjct 441 RQIIKNKIMAIGRISRVFSVLREERESVSE#LKNVSGTQRLPAGTLMLGAEGIKNA 495 |
| Schizosaccharomyces pombe | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 +++|+||| |||+++||||||||| ||| #|| ++ | ||+| | | + +++| Sbjct 441 RQIIKNKIMAIGRISRVFSVLREERESVSE#LKNVSGTQRLPAGTLMLGAEGIKNA 495 |
| Cryptococcus gattii | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGG----KQTLQ 445 +++|+||| |+|+|+||||+|||||| | #|| + + ||+|+|+ | |+|+| Sbjct 74 RQIIKNKILAVGRMSRVFSLLREESERVSE#LKSIAGSNALPAGMLASGAEGIKETIQ 130 |
| Dictyostelium discoideum AX4 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ++++| |++++ || |+||+||+| |+++ #+| +|+ +| |+|+ || |+ | Sbjct 445 RQMLRAKVKSVSKMMRMFSLLRQERETIMM#IKSFSPSRKIPQGLLTEGKDALKKA 499 |
| Dictyostelium discoideum | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ++++| |++++ || |+||+||+| |+++ #+| +|+ +| |+|+ || |+ | Sbjct 445 RQMLRAKVKSVSKMMRMFSLLRQERETIMM#IKSFSPSRKIPQGLLTEGKDALKKA 499 |
| Yarrowia lipolytica | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + +|||| |||+|+|+|+|||+||||| #|| ++ | || | | | | ++ | Sbjct 440 RRALRNKILAIGQMSRLFNVLRQESESVSE#LKAVS-GGKLPQGTLMLGGQGIRDA 493 |
| Gibberella zeae PH-1 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + |+||| |||+++||| ||||||| | #|| ++ | ||+| | | + |++| Sbjct 403 RRAIKNKILAIGRLSRVFQVLREESEKVTE#LKTVS-GGRLPAGTLMLGAEGLKNA 456 |
| Cryptosporidium parvum Iowa II | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQS 446 + +| |++++ ++ |||| |||++| ++ #|||+|| +| |+| ||+ |++ Sbjct 432 DTLRKKVQSVARIMRVFSTLREQNELIVK#LKGVTPGHRIPMGLLLGGRDALEN 484 |
| Cryptosporidium hominis TU502 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQS 446 + +| |++++ ++ |||| |||++| ++ #|||+|| +| |+| ||+ |++ Sbjct 280 DTLRKKVQSVARIMRVFSTLREQNELIVK#LKGVTPGHRIPMGLLLGGRDALEN 332 |
| Paramecium tetraurelia strain d4-2 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVE 450 | ++||++ + | ++ ||||||||+ #||| | || |+|| || + | + Sbjct 411 EKLKNKLKFVATMMKLQKTLREESESVMK#LKGACPDKRLPKGILSAGKTAISDALAD 467 |
| Candida glabrata | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTL 444 ++ +|||| || |++|++|||||||+ | #|| + +|+|| | |+ | | | Sbjct 478 RKTLRNKILAIAKVSRMYSVLREESDKVQY#LKSMN-SGILPRGALAHGSQGL 528 |
| Chaetomium globosum CBS 148.51 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + |+||| |||+++||| ||||||| | #|| ++ | ||+| | | + +++| Sbjct 409 RRAIKNKILAIGRLSRVFQVLREESERVTE#LKTVS-GGRLPAGTLMLGAEGIKNA 462 |
| Aspergillus oryzae RIB40 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + |+||| |||+++||| ||||||| | #|| | | ||+| | | + ++ | Sbjct 428 RRAIKNKILAIGRLSRVFQVLREESERVTE#LKTAT-GGRLPAGTLMLGAEGIKQA 481 |
| Aspergillus oryzae | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + |+||| |||+++||| ||||||| | #|| | | ||+| | | + ++ | Sbjct 403 RRAIKNKILAIGRLSRVFQVLREESERVTE#LKTAT-GGRLPAGTLMLGAEGIKQA 456 |
| Aspergillus parasiticus | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + |+||| |||+++||| ||||||| | #|| | | ||+| | | + ++ | Sbjct 404 RRAIKNKILAIGRLSRVFQVLREESERVTE#LKTAT-GGRLPAGTLMLGAEGIKQA 457 |
| Neurospora crassa | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + |+||| |||+++||| ||||||| | #|| ++ | ||+| | | + +++| Sbjct 406 RRAIKNKILAIGRLSRVFQVLREESERVTE#LKTVS-GGRLPAGTLMLGAEGIKNA 459 |
| Candida albicans SC5314 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQS 446 |+ +|||| |||||+|+| ||||| |+| #|| | | || | | | |++ Sbjct 497 KQALRNKIIAIGKMSRMFQVLREEQENVAH#LKELN-RGSLPKGSLLHGADGLKN 549 |
| Aspergillus nidulans FGSC A4 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + |+||| |||+++||| ||||||| | #|| | ||+| | | + ++ | Sbjct 406 RRAIKNKILAIGRLSRVFQVLREESERVTE#LK-TAAGGRLPAGTLMLGAEGIKQA 459 |
| Aspergillus fumigatus Af293 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + |+||| |||+++||| ||||||| | #|| | ||+| | | + ++ | Sbjct 427 RRAIKNKILAIGRLSRVFQVLREESERVTE#LK-TAAGGRLPAGTLMLGAEGIKQA 480 |
| Plasmodium yoelii yoelii str. 17XNL | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQS 446 + +| |+++||++ ||| ||+|+| ++ #||| +| +| |+| ||+ |++ Sbjct 449 DALRKKVQSIGRLMRVFRTLRKENELIVQ#LKGCSPGYKIPVGLLLSGKEGLEN 501 |
| Plasmodium chabaudi chabaudi | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQS 446 + +| |+++||++ ||| ||+|+| ++ #||| +| +| |+| ||+ |++ Sbjct 458 DALRKKVQSIGRLMRVFRTLRKENELIVQ#LKGCSPGYKIPVGLLLSGKEGLEN 510 |
| Plasmodium falciparum 3D7 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQS 446 + +| |++++|++ ||| ||+|+| ++ #||| +| +| |+| ||+ |++ Sbjct 530 DTLRKKVQSVGRLMRVFRTLRKENELIVQ#LKGCSPGYRIPVGLLLSGKEGLEN 582 |
| Ashbya gossypii ATCC 10895 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + +|+|| || |++|++|||||||+ | #|| + +|+|| | || | + | | Sbjct 483 RRALRSKILAIAKVSRMYSVLREESDKVQY#LKTMN-SGVLPRGALSRGSEGLNEA 536 |
| Exophiala dermatitidis | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 + |+||| |||+++||| ||||||+ | #|| | ||+| | | + ++ | Sbjct 426 RRAIKNKILAIGRLSRVFQVLREESQRVTE#LK-TQAGGRLPAGTLMLGAEGIKQA 479 |
| Paramecium tetraurelia | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVE 450 | +++|++ + | ++ |||+|||++ #||| | || |+|| || + | + Sbjct 414 EKLKSKLKFVATMMKMQKTLREQSESIMK#LKGACPDKRLPKGILSAGKTAITDALAD 470 |
| Plasmodium berghei strain ANKA | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQS 446 + +| |+++||++ ||| ||+|+| ++ #||| +| +| |+| |++ |++ Sbjct 457 DALRKKVQSIGRLMRVFRTLRKENELIVQ#LKGCSPGYKIPVGLLLRGRKGLEN 509 |
| Toxoplasma gondii | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQ 442 + +| |++++|++ ||| ||+|+| ++ #||| || +| |+| |++ Sbjct 423 DALRKKVQSVGRLMRVFKTLRQENELIVR#LKGCTPGHRIPVGLLLQGRE 471 |
| Saccharomyces cerevisiae | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ++ +|||| |+ |++|++||||||+ | #|| +|+|| | || | + | | Sbjct 403 RKALRNKILAVAKVSRMYSVLREETNKVQF#LKDHN-SGVLPRGALSNGVKGLDEA 456 |
| Paramecium tetraurelia | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATVE 450 | ++ || + | ++ |||+|||++ #||| | || |||+ || + | + Sbjct 412 EKLKKKIIFVANMIKMQKTLREQSESIIY#LKGACPDKRLPRGVLTAGKSAIMDALAD 468 |
| Ustilago maydis | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVL 437 + +|+||| |+|+|+|||++||||+| | #|| + | || | | Sbjct 435 RTLIKNKILAVGRMSRVFALLREEAERVSE#LKS-SQTAKLPYGSL 478 |
| Ustilago maydis 521 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVL 437 + +|+||| |+|+|+|||++||||+| | #|| + | || | | Sbjct 435 RTLIKNKILAVGRMSRVFALLREEAERVSE#LKS-SQTAKLPYGSL 478 |
| Dictyostelium discoideum AX4 | Query 393 KEVIRNKIRAIGKMARVFSVLREESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSA 447 ++++| ++++ || |+||+||+| |+++ #+| + + + |+|+ || |+ | Sbjct 70 RQLLRANVKSVSKM-RMFSLLRQEHETIMM#IKSFSASRKITQGLLTEGKDALKKA 123 |
| Tetrahymena thermophila SB210 | Query 414 REESESVLT#LKGLTPTGMLPSGVLSGGKQTLQSATV 449 |||||++| #||| | +| |+|| | ++ | Sbjct 477 REESETILQ#LKGQCPDKRIPKGLLSSGVSAIKDNRV 512 |
| mice, Ehrlich ascites tumor cells, Peptide Partial, 96 aa | Query 393 KEVIRNKIRAIGKM 406 |||||||||||||| Query 393 KEVIRNKIRAIGKM 406 |
| mice, Ehrlich ascites tumor cells, Peptide Partial, 97 aa | Query 393 KEVIRNKIRAIGKM 406 ||+||||||||||| Sbjct 84 KEIIRNKIRAIGKM 97 |
[Site 3] REESESVLTL423-KGLTPTGMLP
Leu423 Lys
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Arg414 | Glu415 | Glu416 | Ser417 | Glu418 | Ser419 | Val420 | Leu421 | Thr422 | Leu423 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Lys424 | Gly425 | Leu426 | Thr427 | Pro428 | Thr429 | Gly430 | Met431 | Leu432 | Pro433 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| EVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIE |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 121.00 | 6 | protein phosphatase 3, catalytic subunit, alpha i |
| 2 | Rattus norvegicus | 121.00 | 3 | protein phosphatase 3, catalytic subunit, alpha i |
| 3 | Xenopus laevis | 121.00 | 2 | protein phosphatase 3, catalytic subunit, alpha i |
| 4 | Bos taurus | 121.00 | 2 | protein phosphatase 3, catalytic subunit, alpha i |
| 5 | N/A | 120.00 | 14 | calcineurin |
| 6 | Mus musculus | 118.00 | 6 | protein phosphatase 3, catalytic subunit, beta is |
| 7 | Canis familiaris | 118.00 | 5 | PREDICTED: similar to protein phosphatase 3 (form |
| 8 | Canis familiaris | 118.00 | 5 | PREDICTED: similar to protein phosphatase 3, cata |
| 9 | Oryctolagus cuniculus | 118.00 | 2 | protein phosphatase 3 (formerly 2B), catalytic su |
| 10 | Tetraodon nigroviridis | 113.00 | 4 | unnamed protein product |
| 11 | Sus scrofa | 110.00 | 1 | protein phosphatase 3, catalytic subunit, alpha i |
| 12 | Gallus gallus | 110.00 | 1 | calcineurin A alpha |
| 13 | Xenopus laevis | 110.00 | 1 | calcineurin catalytic subunit |
| 14 | Macaca mulatta | 110.00 | 1 | PREDICTED: protein phosphatase 3 (formerly 2B), c |
| 15 | Pan troglodytes | 106.00 | 1 | PREDICTED: protein phosphatase 3 (formerly 2B), c |
| 16 | Drosophila melanogaster | 96.70 | 3 | Protein phosphatase 2B at 14D CG9842-PA |
| 17 | Drosophila pseudoobscura | 96.70 | 1 | GA22069-PA |
| 18 | Mizuhopecten yessoensis | 93.20 | 1 | calcineurin A |
| 19 | Bombyx mori | 92.00 | 1 | calcineurin A |
| 20 | Schistosoma japonicum | 90.10 | 1 | SJCHGC09435 protein |
| 21 | Drosophila melanogaster | 90.10 | 1 | Calcineurin A1 CG1455-PA |
| 22 | Schistosoma mansoni | 89.40 | 1 | calcineurin A |
| 23 | Caenorhabditis elegans | 85.90 | 2 | abnormal CHEmotaxis family member (tax-6) |
| 24 | Caenorhabditis briggsae AF16 | 85.50 | 1 | Hypothetical protein CBG08362 |
| 25 | Filobasidiella neoformans | 60.80 | 1 | AF159511_1 calcineurin A catalytic subunit |
| 26 | Cryptococcus neoformans var. neoformans JEC21 | 60.50 | 1 | calcineurin A catalytic subunit |
| 27 | Schizosaccharomyces pombe 972h- | 59.30 | 1 | calcineurin catalytic subunit Ppb1 |
| 28 | Schizosaccharomyces pombe | 59.30 | 1 | protein phosphatase 2B |
| 29 | Cryptococcus gattii | 57.00 | 1 | calcineurin A catalytic subunit |
| 30 | Dictyostelium discoideum AX4 | 55.50 | 1 | calcineurin A |
| 31 | Dictyostelium discoideum | 55.50 | 1 | calcineurin A |
| 32 | Cryptosporidium parvum Iowa II | 54.70 | 1 | protein phosphatase 2B catalytic subunit, calcine |
| 33 | Cryptosporidium hominis TU502 | 54.70 | 1 | protein phosphatase 2b |
| 34 | Paramecium tetraurelia strain d4-2 | 53.90 | 8 | hypothetical protein GSPATT00033854001 |
| 35 | Yarrowia lipolytica | 53.90 | 2 | hypothetical protein |
| 36 | Gibberella zeae PH-1 | 53.90 | 1 | P2B_NEUCR SERINE/THREONINE PROTEIN PHOSPHATASE 2B |
| 37 | Aspergillus parasiticus | 52.80 | 1 | calcineurin A |
| 38 | Chaetomium globosum CBS 148.51 | 52.80 | 1 | serine/threonine protein phosphatase 2B catalytic |
| 39 | Aspergillus oryzae RIB40 | 52.80 | 1 | hypothetical protein |
| 40 | Neurospora crassa | 52.80 | 1 | phosphoprotein phosphatase 3-alpha catalytic chai |
| 41 | Aspergillus oryzae | 52.80 | 1 | calcineurin A |
| 42 | Candida glabrata | 52.40 | 1 | unnamed protein product |
| 43 | Candida albicans SC5314 | 51.60 | 2 | hypothetical protein CaO19_6033 |
| 44 | Plasmodium chabaudi chabaudi | 51.60 | 1 | protein phosphatase |
| 45 | Plasmodium yoelii yoelii str. 17XNL | 51.60 | 1 | protein phosphatase 2B |
| 46 | Plasmodium falciparum 3D7 | 51.20 | 1 | protein phosphatase, putative |
| 47 | Aspergillus nidulans FGSC A4 | 51.20 | 1 | P2B_EMENI SERINE/THREONINE PROTEIN PHOSPHATASE 2B |
| 48 | Aspergillus fumigatus Af293 | 50.80 | 1 | calcineurin catalytic subunit CnaA |
| 49 | Ashbya gossypii ATCC 10895 | 50.40 | 1 | AER118Cp |
| 50 | Paramecium tetraurelia | 49.70 | 4 | calcineurin-A5-2 |
| 51 | Plasmodium berghei strain ANKA | 49.70 | 1 | protein phosphatase |
| 52 | Toxoplasma gondii | 49.70 | 1 | protein phosphatase 2B catalytic subunit |
| 53 | Exophiala dermatitidis | 49.70 | 1 | calcineurin |
| 54 | Saccharomyces cerevisiae | 47.80 | 2 | phosphatase 2Bw catalytic subunit |
| 55 | Paramecium tetraurelia | 47.40 | 1 | protein phosphatase 2B |
| 56 | Ustilago maydis | 46.20 | 1 | calcineurin catalytic subunit; Ucn1 |
| 57 | Ustilago maydis 521 | 46.20 | 1 | hypothetical protein UM00936.1 |
| 58 | Dictyostelium discoideum AX4 | 42.00 | 1 | hypothetical protein DDBDRAFT_0205063 |
| 59 | Tetrahymena thermophila SB210 | 36.20 | 1 | Ser/Thr protein phosphatase family protein |
| 60 | mice, Ehrlich ascites tumor cells, Peptide Partial, 96 aa | 30.00 | 1 | calcium/calmodulin-dependent protein phosphatase |
| 61 | mice, Ehrlich ascites tumor cells, Peptide Partial, 97 aa | 29.60 | 1 | calcium/calmodulin-dependent protein phosphatase |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |
| Rattus norvegicus | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |
| Xenopus laevis | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |
| Bos taurus | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |
| N/A | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |
| Mus musculus | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |+||||||||||||||||||||||||||||#||||||||||||||+||+|||||||||||| Sbjct 404 EIIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLAGGRQTLQSATVEAIE 463 |
| Canis familiaris | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |+||||||||||||||||||||||||||||#||||||||||||||+||+|||||||||||| Sbjct 403 EIIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLAGGRQTLQSATVEAIE 462 |
| Canis familiaris | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |+||||||||||||||||||||||||||||#||||||||||||||+||+|||||||||||| Sbjct 400 EIIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLAGGRQTLQSATVEAIE 459 |
| Oryctolagus cuniculus | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |+||||||||||||||||||||||||||||#||||||||||||||+||+|||||||||||| Sbjct 403 EIIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLAGGRQTLQSATVEAIE 462 |
| Tetraodon nigroviridis | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 |||+||||||||||++|||||||||+||||#|||||||||||||||||+|||||||+|||| Sbjct 449 EVIKNKIRAIGKMAKMFSVLREESENVLTL#KGLTPTGMLPSGVLSGGRQTLQSATIEAIE 508 |
| Sus scrofa | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||| Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Gallus gallus | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||| Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Xenopus laevis | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||| Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Macaca mulatta | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||| Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |
| Pan troglodytes | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||||||||||||||||||||||||||||#||||||||||||||+||+||||| Sbjct 421 EIIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLAGGRQTLQSG 474 |
| Drosophila melanogaster | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |||||||||||||||||||||||||||| |#||||||| || | ||||||+|++| Sbjct 462 EVIRNKIRAIGKMARVFSVLREESESVLQL#KGLTPTGALPLGALSGGKQSLKNA 515 |
| Drosophila pseudoobscura | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |||||||||||||||||||||||||||| |#||||||| || | ||||||+|++| Sbjct 389 EVIRNKIRAIGKMARVFSVLREESESVLQL#KGLTPTGALPLGALSGGKQSLKNA 442 |
| Mizuhopecten yessoensis | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |||+|||||||||||||+|||||||||| |#||||| |+|| | ||||| || || Sbjct 394 EVIKNKIRAIGKMARVFTVLREESESVLQL#KGLTPNGLLPLGALSGGKDTLTSA 447 |
| Bombyx mori | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |||||||||||||| ||||||||||||| |#||||||| || | ||||| +|++| Sbjct 391 EVIRNKIRAIGKMAHVFSVLREESESVLQL#KGLTPTGALPLGALSGGKTSLKNA 444 |
| Schistosoma japonicum | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||| |+||||||||| |#||||| |||| | |||||++| | Sbjct 115 EVIRNKIRAIGKMARTFTVLREESESVFEL#KGLTPNGMLPLGALSGGKESLNKA 168 |
| Drosophila melanogaster | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+|||||||||||+||||+||||||||| |#||||||| || | ||||+ +|+ | Sbjct 462 EIIRNKIRAIGKMSRVFSILREESESVLQL#KGLTPTGALPVGALSGGRDSLKEA 515 |
| Schistosoma mansoni | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSAT 448 +||||||||||||||||+|||||||++| |#|||||||||| | |+||++ +++ + Sbjct 390 DVIRNKIRAIGKMARVFTVLREESETILEL#KGLTPTGMLPLGALAGGREAIKAVS 444 |
| Caenorhabditis elegans | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEA 451 ||||+|||||||||| |||||||||||| |#||||||| || | | || + ++ |+ Sbjct 420 EVIRHKIRAIGKMARAFSVLREESESVLAL#KGLTPTGALPMGTLQGGSRGVREVAAES 477 |
| Caenorhabditis briggsae AF16 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQS-ATVEAI 452 ||||+|||||||||| |||||||||||| |#||||||| ||+| | || + ++ | | + Sbjct 401 EVIRHKIRAIGKMARAFSVLREESESVLAL#KGLTPTGALPAGTLQGGSRGIREVAAVSGV 460 Query 453 E 453 + Sbjct 461 D 461 |
| Filobasidiella neoformans | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 ++|+||| |+|+|+||||+|||||| | |#| ++ + ||+|+|+ | + ++ | Sbjct 432 QIIKNKILAVGRMSRVFSLLREESERVSEL#KSISGSNALPAGMLASGAEGIKEA 485 |
| Cryptococcus neoformans var. neoformans JEC21 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 ++|+||| |+|+|+||||+|||||| | |#| ++ + ||+|+|+ | + ++ | Sbjct 419 QIIKNKILAVGRMSRVFSLLREESERVSEL#KSISGSNALPAGMLASGAEGIKEA 472 |
| Schizosaccharomyces pombe 972h- | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 ++|+||| |||+++||||||||| ||| |#| ++ | ||+| | | + +++| Sbjct 442 QIIKNKIMAIGRISRVFSVLREERESVSEL#KNVSGTQRLPAGTLMLGAEGIKNA 495 |
| Schizosaccharomyces pombe | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 ++|+||| |||+++||||||||| ||| |#| ++ | ||+| | | + +++| Sbjct 442 QIIKNKIMAIGRISRVFSVLREERESVSEL#KNVSGTQRLPAGTLMLGAEGIKNA 495 |
| Cryptococcus gattii | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGG----KQTLQ 445 ++|+||| |+|+|+||||+|||||| | |#| + + ||+|+|+ | |+|+| Sbjct 75 QIIKNKILAVGRMSRVFSLLREESERVSEL#KSIAGSNALPAGMLASGAEGIKETIQ 130 |
| Dictyostelium discoideum AX4 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 +++| |++++ || |+||+||+| |+++ +#| +|+ +| |+|+ || |+ | Sbjct 446 QMLRAKVKSVSKMMRMFSLLRQERETIMMI#KSFSPSRKIPQGLLTEGKDALKKA 499 |
| Dictyostelium discoideum | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 +++| |++++ || |+||+||+| |+++ +#| +|+ +| |+|+ || |+ | Sbjct 446 QMLRAKVKSVSKMMRMFSLLRQERETIMMI#KSFSPSRKIPQGLLTEGKDALKKA 499 |
| Cryptosporidium parvum Iowa II | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQS 446 + +| |++++ ++ |||| |||++| ++ |#||+|| +| |+| ||+ |++ Sbjct 432 DTLRKKVQSVARIMRVFSTLREQNELIVKL#KGVTPGHRIPMGLLLGGRDALEN 484 |
| Cryptosporidium hominis TU502 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQS 446 + +| |++++ ++ |||| |||++| ++ |#||+|| +| |+| ||+ |++ Sbjct 280 DTLRKKVQSVARIMRVFSTLREQNELIVKL#KGVTPGHRIPMGLLLGGRDALEN 332 |
| Paramecium tetraurelia strain d4-2 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVE 450 | ++||++ + | ++ ||||||||+ |#|| | || |+|| || + | + Sbjct 411 EKLKNKLKFVATMMKLQKTLREESESVMKL#KGACPDKRLPKGILSAGKTAISDALAD 467 |
| Yarrowia lipolytica | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 +|||| |||+|+|+|+|||+||||| |#| ++ | || | | | | ++ | Sbjct 443 LRNKILAIGQMSRLFNVLRQESESVSEL#KAVS-GGKLPQGTLMLGGQGIRDA 493 |
| Gibberella zeae PH-1 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | |#| ++ | ||+| | | + |++| Sbjct 406 IKNKILAIGRLSRVFQVLREESEKVTEL#KTVS-GGRLPAGTLMLGAEGLKNA 456 |
| Aspergillus parasiticus | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | |#| | | ||+| | | + ++ | Sbjct 407 IKNKILAIGRLSRVFQVLREESERVTEL#KTAT-GGRLPAGTLMLGAEGIKQA 457 |
| Chaetomium globosum CBS 148.51 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | |#| ++ | ||+| | | + +++| Sbjct 412 IKNKILAIGRLSRVFQVLREESERVTEL#KTVS-GGRLPAGTLMLGAEGIKNA 462 |
| Aspergillus oryzae RIB40 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | |#| | | ||+| | | + ++ | Sbjct 431 IKNKILAIGRLSRVFQVLREESERVTEL#KTAT-GGRLPAGTLMLGAEGIKQA 481 |
| Neurospora crassa | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | |#| ++ | ||+| | | + +++| Sbjct 409 IKNKILAIGRLSRVFQVLREESERVTEL#KTVS-GGRLPAGTLMLGAEGIKNA 459 |
| Aspergillus oryzae | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | |#| | | ||+| | | + ++ | Sbjct 406 IKNKILAIGRLSRVFQVLREESERVTEL#KTAT-GGRLPAGTLMLGAEGIKQA 456 |
| Candida glabrata | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTL 444 + +|||| || |++|++|||||||+ | |#| + +|+|| | |+ | | | Sbjct 479 KTLRNKILAIAKVSRMYSVLREESDKVQYL#KSMN-SGILPRGALAHGSQGL 528 |
| Candida albicans SC5314 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVEAIE 453 + +|||| |||||+|+| ||||| |+| |#| | | || | | | |++ |+ + | Sbjct 498 QALRNKIIAIGKMSRMFQVLREEQENVAHL#KELN-RGSLPKGSLLHGADGLKN-TINSFE 555 |
| Plasmodium chabaudi chabaudi | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQS 446 + +| |+++||++ ||| ||+|+| ++ |#|| +| +| |+| ||+ |++ Sbjct 458 DALRKKVQSIGRLMRVFRTLRKENELIVQL#KGCSPGYKIPVGLLLSGKEGLEN 510 |
| Plasmodium yoelii yoelii str. 17XNL | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQS 446 + +| |+++||++ ||| ||+|+| ++ |#|| +| +| |+| ||+ |++ Sbjct 449 DALRKKVQSIGRLMRVFRTLRKENELIVQL#KGCSPGYKIPVGLLLSGKEGLEN 501 |
| Plasmodium falciparum 3D7 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQS 446 + +| |++++|++ ||| ||+|+| ++ |#|| +| +| |+| ||+ |++ Sbjct 530 DTLRKKVQSVGRLMRVFRTLRKENELIVQL#KGCSPGYRIPVGLLLSGKEGLEN 582 |
| Aspergillus nidulans FGSC A4 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | |#| | ||+| | | + ++ | Sbjct 409 IKNKILAIGRLSRVFQVLREESERVTEL#K-TAAGGRLPAGTLMLGAEGIKQA 459 |
| Aspergillus fumigatus Af293 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | |#| | ||+| | | + ++ | Sbjct 430 IKNKILAIGRLSRVFQVLREESERVTEL#K-TAAGGRLPAGTLMLGAEGIKQA 480 |
| Ashbya gossypii ATCC 10895 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 +|+|| || |++|++|||||||+ | |#| + +|+|| | || | + | | Sbjct 486 LRSKILAIAKVSRMYSVLREESDKVQYL#KTMN-SGVLPRGALSRGSEGLNEA 536 |
| Paramecium tetraurelia | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVE 450 | +++|++ + | ++ |||+|||++ |#|| | || |+|| || + | + Sbjct 414 EKLKSKLKFVATMMKMQKTLREQSESIMKL#KGACPDKRLPKGILSAGKTAITDALAD 470 |
| Plasmodium berghei strain ANKA | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQS 446 + +| |+++||++ ||| ||+|+| ++ |#|| +| +| |+| |++ |++ Sbjct 457 DALRKKVQSIGRLMRVFRTLRKENELIVQL#KGCSPGYKIPVGLLLRGRKGLEN 509 |
| Toxoplasma gondii | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQ 442 + +| |++++|++ ||| ||+|+| ++ |#|| || +| |+| |++ Sbjct 423 DALRKKVQSVGRLMRVFKTLRQENELIVRL#KGCTPGHRIPVGLLLQGRE 471 |
| Exophiala dermatitidis | Query 396 IRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||+ | |#| | ||+| | | + ++ | Sbjct 429 IKNKILAIGRLSRVFQVLREESQRVTEL#K-TQAGGRLPAGTLMLGAEGIKQA 479 |
| Saccharomyces cerevisiae | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 + +|||| |+ |++|++||||||+ | |#| +|+|| | || | + | | Sbjct 404 KALRNKILAVAKVSRMYSVLREETNKVQFL#KDHN-SGVLPRGALSNGVKGLDEA 456 |
| Paramecium tetraurelia | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATVE 450 | ++ || + | ++ |||+|||++ |#|| | || |||+ || + | + Sbjct 412 EKLKKKIIFVANMIKMQKTLREQSESIIYL#KGACPDKRLPRGVLTAGKSAIMDALAD 468 |
| Ustilago maydis | Query 395 VIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVL 437 +|+||| |+|+|+|||++||||+| | |#| + | || | | Sbjct 437 LIKNKILAVGRMSRVFALLREEAERVSEL#KS-SQTAKLPYGSL 478 |
| Ustilago maydis 521 | Query 395 VIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVL 437 +|+||| |+|+|+|||++||||+| | |#| + | || | | Sbjct 437 LIKNKILAVGRMSRVFALLREEAERVSEL#KS-SQTAKLPYGSL 478 |
| Dictyostelium discoideum AX4 | Query 394 EVIRNKIRAIGKMARVFSVLREESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSA 447 +++| ++++ || |+||+||+| |+++ +#| + + + |+|+ || |+ | Sbjct 71 QLLRANVKSVSKM-RMFSLLRQEHETIMMI#KSFSASRKITQGLLTEGKDALKKA 123 |
| Tetrahymena thermophila SB210 | Query 414 REESESVLTL#KGLTPTGMLPSGVLSGGKQTLQSATV 449 |||||++| |#|| | +| |+|| | ++ | Sbjct 477 REESETILQL#KGQCPDKRIPKGLLSSGVSAIKDNRV 512 |
| mice, Ehrlich ascites tumor cells, Peptide Partial, 96 aa | Query 394 EVIRNKIRAIGKM 406 ||||||||||||| Query 394 EVIRNKIRAIGKM 406 |
| mice, Ehrlich ascites tumor cells, Peptide Partial, 97 aa | Query 394 EVIRNKIRAIGKM 406 |+||||||||||| Sbjct 85 EIIRNKIRAIGKM 97 |
[Site 4] ESESVLTLKG425-LTPTGMLPSG
Gly425 Leu
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu416 | Ser417 | Glu418 | Ser419 | Val420 | Leu421 | Thr422 | Leu423 | Lys424 | Gly425 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Leu426 | Thr427 | Pro428 | Thr429 | Gly430 | Met431 | Leu432 | Pro433 | Ser434 | Gly435 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| IRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEAD |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 121.00 | 6 | protein phosphatase 3, catalytic subunit, alpha i |
| 2 | Rattus norvegicus | 121.00 | 3 | protein phosphatase 3, catalytic subunit, alpha i |
| 3 | Xenopus laevis | 121.00 | 2 | protein phosphatase 3, catalytic subunit, alpha i |
| 4 | Bos taurus | 121.00 | 2 | protein phosphatase 3, catalytic subunit, alpha i |
| 5 | N/A | 120.00 | 14 | calcineurin |
| 6 | Mus musculus | 117.00 | 6 | protein phosphatase 3, catalytic subunit, beta is |
| 7 | Canis familiaris | 117.00 | 5 | PREDICTED: similar to protein phosphatase 3 (form |
| 8 | Canis familiaris | 117.00 | 5 | PREDICTED: similar to protein phosphatase 3, cata |
| 9 | Oryctolagus cuniculus | 117.00 | 2 | protein phosphatase 3 (formerly 2B), catalytic su |
| 10 | Tetraodon nigroviridis | 111.00 | 4 | unnamed protein product |
| 11 | Xenopus laevis | 106.00 | 1 | calcineurin catalytic subunit |
| 12 | Sus scrofa | 106.00 | 1 | protein phosphatase 3, catalytic subunit, alpha i |
| 13 | Macaca mulatta | 106.00 | 1 | PREDICTED: protein phosphatase 3 (formerly 2B), c |
| 14 | Gallus gallus | 106.00 | 1 | calcineurin A alpha |
| 15 | Pan troglodytes | 102.00 | 1 | PREDICTED: protein phosphatase 3 (formerly 2B), c |
| 16 | Drosophila melanogaster | 93.20 | 3 | Protein phosphatase 2B at 14D CG9842-PA |
| 17 | Drosophila pseudoobscura | 93.20 | 1 | GA22069-PA |
| 18 | Mizuhopecten yessoensis | 89.40 | 1 | calcineurin A |
| 19 | Bombyx mori | 88.20 | 1 | calcineurin A |
| 20 | Schistosoma mansoni | 87.00 | 1 | calcineurin A |
| 21 | Drosophila melanogaster | 86.70 | 1 | Calcineurin A1 CG1455-PA |
| 22 | Schistosoma japonicum | 86.30 | 1 | SJCHGC09435 protein |
| 23 | Caenorhabditis elegans | 82.40 | 2 | abnormal CHEmotaxis family member (tax-6) |
| 24 | Caenorhabditis briggsae AF16 | 81.60 | 1 | Hypothetical protein CBG08362 |
| 25 | Filobasidiella neoformans | 58.90 | 1 | AF159511_1 calcineurin A catalytic subunit |
| 26 | Cryptococcus neoformans var. neoformans JEC21 | 58.50 | 1 | calcineurin A catalytic subunit |
| 27 | Schizosaccharomyces pombe 972h- | 57.40 | 1 | calcineurin catalytic subunit Ppb1 |
| 28 | Schizosaccharomyces pombe | 57.40 | 1 | protein phosphatase 2B |
| 29 | Yarrowia lipolytica | 55.10 | 2 | hypothetical protein |
| 30 | Cryptococcus gattii | 55.10 | 1 | calcineurin A catalytic subunit |
| 31 | Dictyostelium discoideum AX4 | 54.30 | 1 | calcineurin A |
| 32 | Cryptosporidium parvum Iowa II | 54.30 | 1 | protein phosphatase 2B catalytic subunit, calcine |
| 33 | Dictyostelium discoideum | 54.30 | 1 | calcineurin A |
| 34 | Cryptosporidium hominis TU502 | 54.30 | 1 | protein phosphatase 2b |
| 35 | Gibberella zeae PH-1 | 53.90 | 1 | P2B_NEUCR SERINE/THREONINE PROTEIN PHOSPHATASE 2B |
| 36 | Paramecium tetraurelia strain d4-2 | 52.80 | 7 | hypothetical protein GSPATT00033854001 |
| 37 | Aspergillus parasiticus | 52.80 | 1 | calcineurin A |
| 38 | Aspergillus oryzae | 52.80 | 1 | calcineurin A |
| 39 | Aspergillus oryzae RIB40 | 52.80 | 1 | hypothetical protein |
| 40 | Neurospora crassa | 52.80 | 1 | phosphoprotein phosphatase 3-alpha catalytic chai |
| 41 | Chaetomium globosum CBS 148.51 | 52.80 | 1 | serine/threonine protein phosphatase 2B catalytic |
| 42 | Candida glabrata | 52.40 | 1 | unnamed protein product |
| 43 | Plasmodium chabaudi chabaudi | 51.20 | 1 | protein phosphatase |
| 44 | Plasmodium yoelii yoelii str. 17XNL | 51.20 | 1 | protein phosphatase 2B |
| 45 | Aspergillus nidulans FGSC A4 | 51.20 | 1 | P2B_EMENI SERINE/THREONINE PROTEIN PHOSPHATASE 2B |
| 46 | Aspergillus fumigatus Af293 | 51.20 | 1 | calcineurin catalytic subunit CnaA |
| 47 | Candida albicans SC5314 | 50.80 | 2 | hypothetical protein CaO19_13454 |
| 48 | Ashbya gossypii ATCC 10895 | 50.40 | 1 | AER118Cp |
| 49 | Plasmodium falciparum 3D7 | 50.40 | 1 | protein phosphatase, putative |
| 50 | Exophiala dermatitidis | 49.70 | 1 | calcineurin |
| 51 | Toxoplasma gondii | 49.30 | 1 | protein phosphatase 2B catalytic subunit |
| 52 | Plasmodium berghei strain ANKA | 48.90 | 1 | protein phosphatase |
| 53 | Paramecium tetraurelia | 48.50 | 4 | calcineurin-A5-2 |
| 54 | Saccharomyces cerevisiae | 47.80 | 2 | phosphatase 2Bw catalytic subunit |
| 55 | Paramecium tetraurelia | 46.20 | 1 | protein phosphatase 2B |
| 56 | Ustilago maydis 521 | 45.80 | 1 | hypothetical protein UM00936.1 |
| 57 | Ustilago maydis | 45.80 | 1 | calcineurin catalytic subunit; Ucn1 |
| 58 | Dictyostelium discoideum AX4 | 40.80 | 1 | hypothetical protein DDBDRAFT_0205063 |
| 59 | Tetrahymena thermophila SB210 | 36.20 | 1 | Ser/Thr protein phosphatase family protein |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 |
| Rattus norvegicus | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 |
| Xenopus laevis | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 |
| Bos taurus | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 |
| N/A | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 |
| Mus musculus | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 ||||||||||||||||||||||||||||||#||||||||||||+||+|||||||||||||+ Sbjct 406 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLAGGRQTLQSATVEAIEAE 465 |
| Canis familiaris | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 ||||||||||||||||||||||||||||||#||||||||||||+||+|||||||||||||+ Sbjct 405 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLAGGRQTLQSATVEAIEAE 464 |
| Canis familiaris | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 ||||||||||||||||||||||||||||||#||||||||||||+||+|||||||||||||+ Sbjct 402 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLAGGRQTLQSATVEAIEAE 461 |
| Oryctolagus cuniculus | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEAD 455 ||||||||||||||||||||||||||||||#||||||||||||+||+|||||||||||||+ Sbjct 405 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLAGGRQTLQSATVEAIEAE 464 |
| Tetraodon nigroviridis | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEA 454 |+||||||||||++|||||||||+||||||#|||||||||||||||+|||||||+||||| Sbjct 451 IKNKIRAIGKMAKMFSVLREESENVLTLKG#LTPTGMLPSGVLSGGRQTLQSATIEAIEA 509 |
| Xenopus laevis | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||| Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |
| Sus scrofa | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||| Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |
| Macaca mulatta | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||| Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |
| Gallus gallus | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#|||||||||||||||||||||| Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |
| Pan troglodytes | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||||||||||||||||||||#||||||||||||+||+||||| Sbjct 423 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLAGGRQTLQSG 474 |
| Drosophila melanogaster | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |||||||||||||||||||||||||| |||#||||| || | ||||||+|++| Sbjct 464 IRNKIRAIGKMARVFSVLREESESVLQLKG#LTPTGALPLGALSGGKQSLKNA 515 |
| Drosophila pseudoobscura | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |||||||||||||||||||||||||| |||#||||| || | ||||||+|++| Sbjct 391 IRNKIRAIGKMARVFSVLREESESVLQLKG#LTPTGALPLGALSGGKQSLKNA 442 |
| Mizuhopecten yessoensis | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+|||||||||||||+|||||||||| |||#||| |+|| | ||||| || || Sbjct 396 IKNKIRAIGKMARVFTVLREESESVLQLKG#LTPNGLLPLGALSGGKDTLTSA 447 |
| Bombyx mori | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |||||||||||| ||||||||||||| |||#||||| || | ||||| +|++| Sbjct 393 IRNKIRAIGKMAHVFSVLREESESVLQLKG#LTPTGALPLGALSGGKTSLKNA 444 |
| Schistosoma mansoni | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSAT 448 |||||||||||||||+|||||||++| |||#|||||||| | |+||++ +++ + Sbjct 392 IRNKIRAIGKMARVFTVLREESETILELKG#LTPTGMLPLGALAGGREAIKAVS 444 |
| Drosophila melanogaster | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |||||||||||+||||+||||||||| |||#||||| || | ||||+ +|+ | Sbjct 464 IRNKIRAIGKMSRVFSILREESESVLQLKG#LTPTGALPVGALSGGRDSLKEA 515 |
| Schistosoma japonicum | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 ||||||||||||| |+||||||||| |||#||| |||| | |||||++| | Sbjct 117 IRNKIRAIGKMARTFTVLREESESVFELKG#LTPNGMLPLGALSGGKESLNKA 168 |
| Caenorhabditis elegans | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEA 451 ||+|||||||||| |||||||||||| |||#||||| || | | || + ++ |+ Sbjct 422 IRHKIRAIGKMARAFSVLREESESVLALKG#LTPTGALPMGTLQGGSRGVREVAAES 477 |
| Caenorhabditis briggsae AF16 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQS-ATVEAIE 453 ||+|||||||||| |||||||||||| |||#||||| ||+| | || + ++ | | ++ Sbjct 403 IRHKIRAIGKMARAFSVLREESESVLALKG#LTPTGALPAGTLQGGSRGIREVAAVSGVD 461 |
| Filobasidiella neoformans | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |+|+|+||||+|||||| | || #++ + ||+|+|+ | + ++ | Sbjct 434 IKNKILAVGRMSRVFSLLREESERVSELKS#ISGSNALPAGMLASGAEGIKEA 485 |
| Cryptococcus neoformans var. neoformans JEC21 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |+|+|+||||+|||||| | || #++ + ||+|+|+ | + ++ | Sbjct 421 IKNKILAVGRMSRVFSLLREESERVSELKS#ISGSNALPAGMLASGAEGIKEA 472 |
| Schizosaccharomyces pombe 972h- | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||||||||| ||| || #++ | ||+| | | + +++| Sbjct 444 IKNKIMAIGRISRVFSVLREERESVSELKN#VSGTQRLPAGTLMLGAEGIKNA 495 |
| Schizosaccharomyces pombe | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||||||||| ||| || #++ | ||+| | | + +++| Sbjct 444 IKNKIMAIGRISRVFSVLREERESVSELKN#VSGTQRLPAGTLMLGAEGIKNA 495 |
| Yarrowia lipolytica | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIEA 454 +|||| |||+|+|+|+|||+||||| || #++ | || | | | | ++ | || Sbjct 443 LRNKILAIGQMSRLFNVLRQESESVSELKA#VS-GGKLPQGTLMLGGQGIRDAITSFEEA 500 |
| Cryptococcus gattii | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGG----KQTLQ 445 |+||| |+|+|+||||+|||||| | || #+ + ||+|+|+ | |+|+| Sbjct 77 IKNKILAVGRMSRVFSLLREESERVSELKS#IAGSNALPAGMLASGAEGIKETIQ 130 |
| Dictyostelium discoideum AX4 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 +| |++++ || |+||+||+| |+++ +| # +|+ +| |+|+ || |+ | Sbjct 448 LRAKVKSVSKMMRMFSLLRQERETIMMIKS#FSPSRKIPQGLLTEGKDALKKA 499 |
| Cryptosporidium parvum Iowa II | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQS 446 +| |++++ ++ |||| |||++| ++ |||#+|| +| |+| ||+ |++ Sbjct 434 LRKKVQSVARIMRVFSTLREQNELIVKLKG#VTPGHRIPMGLLLGGRDALEN 484 |
| Dictyostelium discoideum | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 +| |++++ || |+||+||+| |+++ +| # +|+ +| |+|+ || |+ | Sbjct 448 LRAKVKSVSKMMRMFSLLRQERETIMMIKS#FSPSRKIPQGLLTEGKDALKKA 499 |
| Cryptosporidium hominis TU502 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQS 446 +| |++++ ++ |||| |||++| ++ |||#+|| +| |+| ||+ |++ Sbjct 282 LRKKVQSVARIMRVFSTLREQNELIVKLKG#VTPGHRIPMGLLLGGRDALEN 332 |
| Gibberella zeae PH-1 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | || #++ | ||+| | | + |++| Sbjct 406 IKNKILAIGRLSRVFQVLREESEKVTELKT#VS-GGRLPAGTLMLGAEGLKNA 456 |
| Paramecium tetraurelia strain d4-2 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVE 450 ++||++ + | ++ ||||||||+ |||# | || |+|| || + | + Sbjct 413 LKNKLKFVATMMKLQKTLREESESVMKLKG#ACPDKRLPKGILSAGKTAISDALAD 467 |
| Aspergillus parasiticus | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | || # | | ||+| | | + ++ | Sbjct 407 IKNKILAIGRLSRVFQVLREESERVTELKT#AT-GGRLPAGTLMLGAEGIKQA 457 |
| Aspergillus oryzae | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | || # | | ||+| | | + ++ | Sbjct 406 IKNKILAIGRLSRVFQVLREESERVTELKT#AT-GGRLPAGTLMLGAEGIKQA 456 |
| Aspergillus oryzae RIB40 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | || # | | ||+| | | + ++ | Sbjct 431 IKNKILAIGRLSRVFQVLREESERVTELKT#AT-GGRLPAGTLMLGAEGIKQA 481 |
| Neurospora crassa | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | || #++ | ||+| | | + +++| Sbjct 409 IKNKILAIGRLSRVFQVLREESERVTELKT#VS-GGRLPAGTLMLGAEGIKNA 459 |
| Chaetomium globosum CBS 148.51 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | || #++ | ||+| | | + +++| Sbjct 412 IKNKILAIGRLSRVFQVLREESERVTELKT#VS-GGRLPAGTLMLGAEGIKNA 462 |
| Candida glabrata | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTL 444 +|||| || |++|++|||||||+ | || #+ +|+|| | |+ | | | Sbjct 481 LRNKILAIAKVSRMYSVLREESDKVQYLKS#MN-SGILPRGALAHGSQGL 528 |
| Plasmodium chabaudi chabaudi | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQS 446 +| |+++||++ ||| ||+|+| ++ |||# +| +| |+| ||+ |++ Sbjct 460 LRKKVQSIGRLMRVFRTLRKENELIVQLKG#CSPGYKIPVGLLLSGKEGLEN 510 |
| Plasmodium yoelii yoelii str. 17XNL | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQS 446 +| |+++||++ ||| ||+|+| ++ |||# +| +| |+| ||+ |++ Sbjct 451 LRKKVQSIGRLMRVFRTLRKENELIVQLKG#CSPGYKIPVGLLLSGKEGLEN 501 |
| Aspergillus nidulans FGSC A4 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | || # | ||+| | | + ++ | Sbjct 409 IKNKILAIGRLSRVFQVLREESERVTELK-#TAAGGRLPAGTLMLGAEGIKQA 459 |
| Aspergillus fumigatus Af293 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||| | || # | ||+| | | + ++ | Sbjct 430 IKNKILAIGRLSRVFQVLREESERVTELK-#TAAGGRLPAGTLMLGAEGIKQA 480 |
| Candida albicans SC5314 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVEAIE 453 +|||| |||||+|+| ||||| |+| || #| | || | | | |++ |+ + | Sbjct 500 LRNKIIAIGKMSRMFQVLREEQENVAHLKE#LN-RGSLPKGSLLHGADGLKN-TINSFE 555 |
| Ashbya gossypii ATCC 10895 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 +|+|| || |++|++|||||||+ | || #+ +|+|| | || | + | | Sbjct 486 LRSKILAIAKVSRMYSVLREESDKVQYLKT#MN-SGVLPRGALSRGSEGLNEA 536 |
| Plasmodium falciparum 3D7 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQS 446 +| |++++|++ ||| ||+|+| ++ |||# +| +| |+| ||+ |++ Sbjct 532 LRKKVQSVGRLMRVFRTLRKENELIVQLKG#CSPGYRIPVGLLLSGKEGLEN 582 |
| Exophiala dermatitidis | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 |+||| |||+++||| ||||||+ | || # | ||+| | | + ++ | Sbjct 429 IKNKILAIGRLSRVFQVLREESQRVTELK-#TQAGGRLPAGTLMLGAEGIKQA 479 |
| Toxoplasma gondii | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQ 442 +| |++++|++ ||| ||+|+| ++ |||# || +| |+| |++ Sbjct 425 LRKKVQSVGRLMRVFKTLRQENELIVRLKG#CTPGHRIPVGLLLQGRE 471 |
| Plasmodium berghei strain ANKA | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQS 446 +| |+++||++ ||| ||+|+| ++ |||# +| +| |+| |++ |++ Sbjct 459 LRKKVQSIGRLMRVFRTLRKENELIVQLKG#CSPGYKIPVGLLLRGRKGLEN 509 |
| Paramecium tetraurelia | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVE 450 +++|++ + | ++ |||+|||++ |||# | || |+|| || + | + Sbjct 416 LKSKLKFVATMMKMQKTLREQSESIMKLKG#ACPDKRLPKGILSAGKTAITDALAD 470 |
| Saccharomyces cerevisiae | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 +|||| |+ |++|++||||||+ | || # +|+|| | || | + | | Sbjct 406 LRNKILAVAKVSRMYSVLREETNKVQFLKD#HN-SGVLPRGALSNGVKGLDEA 456 |
| Paramecium tetraurelia | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATVE 450 ++ || + | ++ |||+|||++ |||# | || |||+ || + | + Sbjct 414 LKKKIIFVANMIKMQKTLREQSESIIYLKG#ACPDKRLPRGVLTAGKSAIMDALAD 468 |
| Ustilago maydis 521 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVL 437 |+||| |+|+|+|||++||||+| | || # + | || | | Sbjct 438 IKNKILAVGRMSRVFALLREEAERVSELKS#-SQTAKLPYGSL 478 |
| Ustilago maydis | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVL 437 |+||| |+|+|+|||++||||+| | || # + | || | | Sbjct 438 IKNKILAVGRMSRVFALLREEAERVSELKS#-SQTAKLPYGSL 478 |
| Dictyostelium discoideum AX4 | Query 396 IRNKIRAIGKMARVFSVLREESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSA 447 +| ++++ || |+||+||+| |+++ +| # + + + |+|+ || |+ | Sbjct 73 LRANVKSVSKM-RMFSLLRQEHETIMMIKS#FSASRKITQGLLTEGKDALKKA 123 |
| Tetrahymena thermophila SB210 | Query 414 REESESVLTLKG#LTPTGMLPSGVLSGGKQTLQSATV 449 |||||++| |||# | +| |+|| | ++ | Sbjct 477 REESETILQLKG#QCPDKRIPKGLLSSGVSAIKDNRV 512 |
* References
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