SB0126 : OTK18
[ CaMP Format ]
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | zinc finger protein 175 [Homo sapiens]; zinc finger protein 175; zinc finger protein OTK18; Zinc finger protein 175; Zinc finger protein OTK18 |
| Gene Names | ZNF175; zinc finger protein 175 |
| Gene Locus | 19q13.4; chromosome 19 |
| GO Function | Not available |
* Information From OMIM
Function: Using binding and mutation analyses, Carlson et al. (2004) showed that both the KRAB and zinc finger regions of OTK18 were required for its transcriptional suppressor function. OTK18 was induced in macrophages following HIV-1 infection and restricted viral infection. OTK18-mediated suppression of HIV-1 replication appeared to involve suppression of HIV-1 Tat-induced viral long-terminal repeat promoter activity.
* Structure Information
1. Primary Information
Length: 711 aa
Average Mass: 81.609 kDa
Monoisotopic Mass: 81.557 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| LYAR-type C2HC zinc finger 1. | 35 | 43 | 9.0 | 0.0 |
| YhfH-like protein 1. | 193 | 199 | 10.0 | 1.0 |
| Adenylate kinase, active site lid 1. | 275 | 291 | 17.0 | 0.9 |
| C2HE / C2H2 / C2HC zinc-binding finger 1. | 308 | 321 | 38.0 | 0.3 |
| C2HE / C2H2 / C2HC zinc-binding finger 2. | 334 | 358 | 36.0 | 1.5 |
| --- cleavage 359 --- | ||||
| YhfH-like protein 2. | 363 | 372 | 13.0 | 0.1 |
| C2HE / C2H2 / C2HC zinc-binding finger 3. | 391 | 407 | 37.0 | 0.4 |
| zinc-ribbon 1. | 418 | 429 | 21.0 | 0.0 |
| YhfH-like protein 3. | 448 | 460 | 15.0 | 0.1 |
| C2HE / C2H2 / C2HC zinc-binding finger 4. | 471 | 486 | 33.0 | 9.5 |
| C2HE / C2H2 / C2HC zinc-binding finger 5. | 500 | 519 | 34.0 | 1.1 |
| C2HE / C2H2 / C2HC zinc-binding finger 6. | 532 | 542 | 38.0 | 0.4 |
| C2HE / C2H2 / C2HC zinc-binding finger 7. | 554 | 577 | 32.0 | 1.5 |
| C2HE / C2H2 / C2HC zinc-binding finger 8. | 584 | 597 | 34.0 | 1.4 |
| C2HE / C2H2 / C2HC zinc-binding finger 9. | 632 | 661 | 26.0 | 1.7 |
| C2HE / C2H2 / C2HC zinc-binding finger 10. | 668 | 694 | 34.0 | 0.4 |
3. Sequence Information
Fasta Sequence: SB0126.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites] cleaved by Calpain 1
Source Reference: [PubMed ID: 19034669] Martinez LB, Walsh SM, Jacobsen MT, Sato S, Wiederin J, Ciborowski P, Ikezu T, Calpain and proteasomal regulation of antiretroviral zinc finger protein OTK18 in human macrophages: visualization in live cells by intramolecular FRET. J Neuroimmune Pharmacol. 2009 Mar;4(1):116-28. doi: 10.1007/s11481-008-9140-4.
Cleavage sites (±10aa)
[Site 1] LLTHQKTHTR359-KKPYKCHDCG
Arg359 
Lys
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Leu350 | Leu351 | Thr352 | His353 | Gln354 | Lys355 | Thr356 | His357 | Thr358 | Arg359 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Lys360 | Lys361 | Pro362 | Tyr363 | Lys364 | Cys365 | His366 | Asp367 | Cys368 | Gly369 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| TGDIPCICKECGKVFIQRSELLTHQKTHTRKKPYKCHDCGKAFFQMLSLFRHQRTHSREK |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | synthetic construct | 68.60 | 4 | zinc finger transcription factor KRAB-HLTR6 |
| 2 | N/A | 67.80 | 9 | C Chain C, Crystal Structure Of A Designed Zinc F |
| 3 | Canis familiaris | 60.50 | 32 | PREDICTED: similar to zinc finger protein 605 |
| 4 | Mus musculus | 57.80 | 14 | zinc finger protein 287 |
| 5 | Bos taurus | 55.10 | 1 | zinc finger protein 323 |
| 6 | Rattus norvegicus | 54.30 | 3 | zinc finger protein 4 |
| 7 | Homo sapiens | 53.50 | 34 | ZNF568 protein |
| 8 | Pongo pygmaeus | 50.40 | 6 | Z585A_PONPY Zinc finger protein 585A gi |
| 9 | Bos taurus | 46.20 | 3 | PREDICTED: similar to zinc finger protein isoform |
| 10 | Homo sapiens | 45.10 | 2 | zinc finger protein 554 |
| 11 | Pan troglodytes | 44.30 | 2 | PREDICTED: zinc finger protein 84 (HPF2) isoform |
| 12 | Rattus norvegicus | 33.50 | 1 | zinc finger protein 287 |
Top-ranked sequences
| organism | matching |
|---|---|
| synthetic construct | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | + +| ||+||| #+||||| +|||+| || ||||||+ || Sbjct 195 TGEKPYACPECGKSFSDKKDLTRHQRTHTG#EKPYKCPECGKSFSTSGSLVRHQRTHTGEK 254 Query 331 GDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ | | |||| | ++| ||+||| #+||||| +|||+| +| ||||||+ || Sbjct 112 GEKPYACPECGKSFSSPADLTRHQRTHTG#EKPYKCPECGKSFSDPGALVRHQRTHTGEK 170 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | |+ ||+||| #+||||| +|||+| |+ | |||||+ || Sbjct 139 TGEKPYKCPECGKSFSDPGALVRHQRTHTG#EKPYKCPECGKSFSQLAHLRAHQRTHTGEK 198 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | | + | ||+||| #+||| | +|||+| | ||||||+ || Sbjct 167 TGEKPYKCPECGKSFSQLAHLRAHQRTHTG#EKPYACPECGKSFSDKKDLTRHQRTHTGEK 226 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | |+ ||+||| #+||||| +|||+| | || |||||+ +| Sbjct 223 TGEKPYKCPECGKSFSTSGSLVRHQRTHTG#EKPYKCPECGKSFSQRHSLTEHQRTHTGKK 282 |
| N/A | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | | |+| ||+||| #+||||| +|||+| + | |||||| +| Sbjct 28 TGEKPYKCPECGKSFSQSSDLQKHQRTHTG#EKPYKCPECGKSFSRSDHLSRHQRTHQNKK 87 Query 332 DIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 + | | |||| | | | | ||+||| #+||||| +|||+| | | +|||||+ || Sbjct 2 EKPYKCPECGKSFSQSSNLQKHQRTHTG#EKPYKCPECGKSFSQSSDLQKHQRTHTGEK 59 |
| Canis familiaris | Query 331 GDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ | | |||| | +|+|||||+||| #+||| | +||||| | || |||||+ || Sbjct 418 GEKPYGCVECGKTFFGKSQLLTHQRTHTG#EKPYDCSECGKAFTQKSSLISHQRTHTGEK 476 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | ++|+| ||+||| #+||| | |||||| | | | |||||+ || Sbjct 249 TGEKPYGCSECGKAFSRKSQLKRHQRTHTV#EKPYGCSDCGKAFSQKLKLITHQRTHTGEK 308 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | |+| |++||+||| #+|||+| +||| | + || |||||+ || Sbjct 445 TGEKPYDCSECGKAFTQKSSLISHQRTHTG#EKPYECTECGKTFSEKSSLIHHQRTHTGEK 504 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | +||| | +|+|+|||+||| #|||| |++| ||| + | |||| |+ || Sbjct 305 TGEKPYQCSDCGKAFFWKSQLITHQRTHTG#KKPYACNECTKAFSRNSLLIRHQRIHTGEK 364 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | + | | +||| | |+ +|+|||+||| #+|||+| ||||||| | |||||+ +| Sbjct 277 TVEKPYGCSDCGKAFSQKLKLITHQRTHTG#EKPYQCSDCGKAFFWKSQLITHQRTHTGKK 336 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | || | | + +|| ||+ || #+||||| +||||| | + | +||| |+ || Sbjct 501 TGEKPFECGECRKAFAWKPQLLRHQRIHTG#EKPYKCSECGKAFVQKVQLIKHQRNHTGEK 560 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||+ ||++ +|| || ||| #+| |+|+|| +|||+ | |||+|| || Sbjct 361 TGEKPYECSECGEAFIRKPQLLKHQITHTG#EKNYQCNDCEEAFFKKSELIRHQKTHLGEK 420 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| |+|+ +|+ ||+ || #+| | | || ||||+ | ||| |+ |+ Sbjct 529 TGEKPYKCSECGKAFVQKVQLIKHQRNHTG#EKTYGCSDCAKAFFEKAQLVIHQRIHTGER 588 Query 336 ICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 +| ||| || ++|+|+ ||+||| #+||| | +||||| | | |||||| || Sbjct 171 LCMECGNVFNKKSQLIIHQRTHTG#EKPYGCSECGKAFSQKSLLTIHQRTHSGEK 224 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | ++| |+ ||+||| #+||++| +| ||| | |||| |+ || Sbjct 473 TGEKPYECTECGKTFSEKSSLIHHQRTHTG#EKPFECGECRKAFAWKPQLLRHQRIHTGEK 532 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 +|+ | | || | | ++| |+ ||+||| #+||| | +||||| + | ||||||+ || Sbjct 221 SGEKPYGCGECQKAFSRKSLLILHQRTHTG#EKPYGCSECGKAFSRKSQLKRHQRTHTVEK 280 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | |+| | ||+||+ #+||| | +| ||| + | |||||+ || Sbjct 193 TGEKPYGCSECGKAFSQKSLLTIHQRTHSG#EKPYGCGECQKAFSRKSLLILHQRTHTGEK 252 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | +| + | ++|||+ ||||| #+||| | +||| || | |||||+ || Sbjct 389 TGEKNYQCNDCEEAFFKKSELIRHQKTHLG#EKPYGCVECGKTFFGKSQLLTHQRTHTGEK 448 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 || | | || | | + | |+ ||+ || #+|||+| +||+|| + | +|| ||+ || Sbjct 333 TGKKPYACNECTKAFSRNSLLIRHQRIHTG#EKPYECSECGEAFIRKPQLLKHQITHTGEK 392 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSRE 388 ||+ | | |||| | ++| |+ ||+ || # | | | +||||| + | |||||++| Sbjct 585 TGERPYKCGECGKSFTRKSHLMRHQRIHTG#DKYYVCSECGKAFSRKSQLVIHQRTHTKE 643 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | +| | | ++++|+ ||+ || #++|||| +|||+| + | |||| |+ +| Sbjct 557 TGEKTYGCSDCAKAFFEKAQLVIHQRIHTG#ERPYKCGECGKSFTRKSHLMRHQRIHTGDK 616 |
| Mus musculus | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | || |||| | | + || ||| || #||||||++| | | | | |||| || || Sbjct 501 TGEKPYICNECGKTFSQSTHLLQHQKIHTG#KKPYKCNECWKVFSQSTYLIRHQRIHSGEK 560 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | +||| | ||+ | ||+ || #+||||| |||| | | | |||||+ || Sbjct 417 TGEKPYECHQCGKAFSQRAHLTIHQRIHTG#EKPYKCEDCGKDFSQRAHLTIHQRTHTGEK 476 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |++||| | ||+ | ||+||| #+||||| +| | | || ||| |+ || Sbjct 445 TGEKPYKCEDCGKDFSQRAHLTIHQRTHTG#EKPYKCLECSKTFSHSSSLINHQRVHTGEK 504 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ || ||| | | + | | +||| #+||||| ||||| | + | +||| |+ || Sbjct 585 TGEKSYICNVCGKAFSQSANLTQHHRTHTG#EKPYKCSVCGKAFSQSVHLTQHQRIHNGEK 644 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ | | ||| + | + | ||+ || #+|||||| ||||| || +|+|||+ |+ Sbjct 641 NGEKPFKCNTCGKAYRQGANLTQHQRVHTG#EKPYKCHHCGKAFIYSSSLNQHRRTHTGER 700 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+|||| | | |+ ||+ || #+|||+|| ||||| | | ||| |+ || Sbjct 396 CEECGKEFKHLSSLIAHQRMHTG#EKPYECHQCGKAFSQRAHLTIHQRIHTGEK 448 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | ||| | | | ||+ | #+||+||+ ||||+ | +| +||| |+ || Sbjct 613 TGEKPYKCSVCGKAFSQSVHLTQHQRIHNG#EKPFKCNTCGKAYRQGANLTQHQRVHTGEK 672 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | || | | | |+ ||+ || #+||| |++||| | | | +||+ |+ +| Sbjct 473 TGEKPYKCLECSKTFSHSSSLINHQRVHTG#EKPYICNECGKTFSQSTHLLQHQKIHTGKK 532 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHS 386 ||+ | | | | | ||+ |+ ||+ || #+||| | ||||| | +| +||| |+ Sbjct 697 TGERPYKCSHCNKDFSQRTCLIQHQRIHTG#EKPYGCRICGKAFTQSTNLIQHQRVHT 753 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | ||| || | | |++||| #++|||| | | | | | +||| |+ || Sbjct 669 TGEKPYKCHHCGKAFIYSSSLNQHRRTHTG#ERPYKCSHCNKDFSQRTCLIQHQRIHTGEK 728 Query 331 GDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 || | | ||| | + || |++ | +#+| |+| +||| | + || ||| |+ || Sbjct 362 GDKPYSCNVCGKQFRKYPSLLAHRENHAK#EKAYECEECGKEFKHLSSLIAHQRMHTGEK 420 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | ||| | | |+ || ||| #+| | |+ ||||| | +| +| |||+ || Sbjct 564 CTACGKAFAHSSTLIQHQTTHTG#EKSYICNVCGKAFSQSANLTQHHRTHTGEK 616 |
| Bos taurus | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |+|||| | ||| |+ ||++|| #+|||+| |||||| || ||+| |+ || Sbjct 262 TGEKPYECEECGKTFSQRSGLIEHQRSHTG#EKPYQCKDCGKAFSASNSLIRHRRIHTGEK 321 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | |||| | | | |+ ||+ || #+|||+| +||| | | | |||+|+ || Sbjct 241 CNECGKSFTQSSVLIQHQRIHTG#EKPYECEECGKTFSQRSGLIEHQRSHTGEK 293 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |+|||| | | |+ ||+ || #+| | |++||||| | ||+| | |+ || Sbjct 318 TGEKPYECEECGKTFRLSSYLVQHQRIHTG#EKRYHCNECGKAFSQNAGLFQHLRIHTGEK 377 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | ||+||| | + |+ |++ || #+|||+| +||| | | +||| |+ || Sbjct 290 TGEKPYQCKDCGKAFSASNSLIRHRRIHTG#EKPYECEECGKTFRLSSYLVQHQRIHTGEK 349 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHS 386 ||+ | | +| | | +|+ |+ ||++|| #++||+| +||||| +| || | |+ Sbjct 374 TGEKPYQCGQCSKSFSRRTLLIKHQRSHTG#ERPYECDECGKAFSHHCNLIRHFRIHT 430 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |||| | | + | | + || #+|||+| | |+| + | +|||+|+ |+ Sbjct 346 TGEKRYHCNECGKAFSQNAGLFQHLRIHTG#EKPYQCGQCSKSFSRRTLLIKHQRSHTGER 405 |
| Rattus norvegicus | Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | |||| | |+ |||||| || #+||++| |||||| | +| ||||||+ || Sbjct 1 CPECGKSFSQKENLLTHQKIHTG#EKPFECKDCGKAFIQKSNLIRHQRTHTGEK 53 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKA 371 ||+ | ||+||| |||+| |+ ||+||| #+||+ | +||| Sbjct 22 TGEKPFECKDCGKAFIQKSNLIRHQRTHTG#EKPFICKECGKP 63 |
| Homo sapiens | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ | |||||| | ++ |+|||| || #+|||||++||||| || +| || | |+ || Sbjct 231 AGEKPYECKECGKAFSRKENLITHQKIHTG#EKPYKCNECGKAFIQMSNLIRHHRIHTGEK 290 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |||||| | |+ |+ |+| || #+||| |++||+|| +| |+ | |+|+ || Sbjct 315 TGEKPYECKECGKSFSQKQNLIEHEKIHTG#EKPYACNECGRAFSRMSSVTLHMRSHTGEK 374 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| ||| | |+ | + || #+||| | || ||| | +| |+| |+ || Sbjct 259 TGEKPYKCNECGKAFIQMSNLIRHHRIHTG#EKPYACKDCWKAFSQKSNLIEHERIHTGEK 318 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | ||+| | | |+| |+ |++ || #+|||+| +|||+| | +| |++ |+ || Sbjct 287 TGEKPYACKDCWKAFSQKSNLIEHERIHTG#EKPYECKECGKSFSQKQNLIEHEKIHTGEK 346 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQ 374 ||+ | | |||+ | + | + | ++|| #+|||||+ ||||| | Sbjct 343 TGEKPYACNECGRAFSRMSSVTLHMRSHTG#EKPYKCNKCGKAFSQ 387 Query 334 PCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | | +||+ | + +|+ |++ | #+|||+| +||||| + +| ||+ |+ || Sbjct 207 PFKCNQCGQDFSHKFDLIRHERIHAG#EKPYECKECGKAFSRKENLITHQKIHTGEK 262 |
| Pongo pygmaeus | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ +| |||| |+|+ | + ||||| |#+||+||++|||+|||+ ||||||| |+ || Sbjct 121 AGEKLYVCIECGKAFVQKPEFIIHQKTHMR#EKPFKCNECGKSFFQVSSLFRHQRIHTGEK 180 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | || |||| | |+|||+|| + || #+|||+| ||||+| + | ||| |+ || Sbjct 625 TGEKPYICSECGKTFRQKSELITHHRIHTG#EKPYECSDCGKSFTKKSQLQVHQRIHTGEK 684 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | +| +||| | || |+||||||| #+| | | ||||| | | ||| |+ || Sbjct 429 TGEKPYMCNKCGKAFTNRSNLITHQKTHTG#EKSYICSKCGKAFTQRSDLITHQRIHTGEK 488 Query 336 ICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 || |||| | ||||+ ||+ || #+||| | |||||| | +| ||| |+ || Sbjct 323 ICTECGKAFTYRSELIIHQRIHTG#EKPYACSDCGKAFTQKSALTVHQRIHTGEK 376 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | +| |||+ ||++| +|||+ || #+|||+| ||||+| | || |+ || Sbjct 541 TGEKPYVCTECGRAFIRKSNFITHQRIHTG#EKPYECSDCGKSFTSKSQLLVHQPLHTGEK 600 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ || +||| | |||+|+|||+ || #+|||+| ||||| | | ||+ |+ |+ Sbjct 457 TGEKSYICSKCGKAFTQRSDLITHQRIHTG#EKPYECSTCGKAFTQKSHLNIHQKIHTGER 516 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | +| |||| | || | |||||| #+||| | +||| | | | | | |+ || Sbjct 597 TGEKPYVCAECGKAFSGRSNLSKHQKTHTG#EKPYICSECGKTFRQKSELITHHRIHTGEK 656 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | +||| | +|+|| || || #+||| | +||||| +| +||+||+ || Sbjct 569 TGEKPYECSDCGKSFTSKSQLLVHQPLHTG#EKPYVCAECGKAFSGRSNLSKHQKTHTGEK 628 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ || |||+ |||++ |+ |++ || #+|||+| +|||+| | ||| |+| | Sbjct 233 TGERSYICIECGQAFIQKTHLIAHRRIHTG#EKPYECSNCGKSFISKSQLQVHQRVHTRVK 292 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | ||| | |+| | ||| || #++ |+||+||||| | | ||+ |+ || Sbjct 485 TGEKPYECSTCGKAFTQKSHLNIHQKIHTG#ERQYECHECGKAFNQKSILIVHQKIHTGEK 544 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||+| +|+| |++ || #+||| |+ ||||| +| ||+||+ || Sbjct 401 TGEKPYKCGHCGKLFTSKSQLHVHKRIHTG#EKPYMCNKCGKAFTNRSNLITHQKTHTGEK 460 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |||| | |+| |+ ||| || #+||| | +||+|| + + ||| |+ || Sbjct 513 TGERQYECHECGKAFNQKSILIVHQKIHTG#EKPYVCTECGRAFIRKSNFITHQRIHTGEK 572 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | +||| | ++|+| ||+ || #+||| | +||||| +| +|| ||+ ++ Sbjct 653 TGEKPYECSDCGKSFTKKSQLQVHQRIHTG#EKPYVCAECGKAFTDRSNLNKHQTTHTGDR 712 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHS 386 ||+ | +| |||| | || | || ||| # +|||| ||| | | || |+ Sbjct 681 TGEKPYVCAECGKAFTDRSNLNKHQTTHTG#DRPYKCGICGKGFVQKSVFSVHQSNHA 737 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | ||| || +|+| ||+ |||# ||| | + || | +| |++ |||| Sbjct 261 TGEKPYECSNCGKSFISKSQLQVHQRVHTR#VKPYICTEYGKVFSNNSNLITHKKVQSREK 320 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | +||| | |+| | ||+ || #+| | | || || | | || |+ || Sbjct 345 TGEKPYACSDCGKAFTQKSALTVHQRIHTG#EKSYICMKCGLAFIQKAHLIAHQIIHTGEK 404 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ || +|| |||++ |+ || || #+||||| ||| | | |+| |+ || Sbjct 373 TGEKSYICMKCGLAFIQKAHLIAHQIIHTG#EKPYKCGHCGKLFTSKSQLHVHKRIHTGEK 432 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | +||| | |+| | ||| || #++ | | +||+|| | | |+| |+ || Sbjct 205 TGERHHECTDCGKAFTQKSTLKMHQKIHTG#ERSYICIECGQAFIQKTHLIAHRRIHTGEK 264 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | +||| | |+| |+| || #++ ++| |||||| | +| ||+ |+ |+ Sbjct 177 TGEKLYECSQCGKGFSYNSDLSIHEKIHTG#ERHHECTDCGKAFTQKSTLKMHQKIHTGER 236 Query 334 PCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | | |||| | | | | ||+ || #+| |+| ||| | | |++ |+ |+ Sbjct 153 PFKCNECGKSFFQVSSLFRHQRIHTG#EKLYECSQCGKGFSYNSDLSIHEKIHTGER 208 Query 331 GDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ | | | |+| |+|+| | | #+| | | +||||| | ||+|| ||| Sbjct 94 GEKPYECAEFEKIFTQKSQLKVHLKVLAG#EKLYVCIECGKAFVQKPEFIIHQKTHMREK 152 |
| Bos taurus | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |||||| ||||| || | + |+ #+|||||++||||| | | ||| |+ || Sbjct 393 TGEKPHKCKECGKGFIQRSSLLMHLRNHSG#EKPYKCNECGKAFSQSAYLLNHQRIHTGEK 452 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+|||+| +| |+ |++ |+|#+||||| +||||| | || ||| |+ || Sbjct 596 CKKCGKIFTSKSSLIDHKRMHSR#EKPYKCTECGKAFTQSAYLFDHQRLHNGEK 648 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 +|+ | | |||| || + |+ ||+ |||#+| |||+|||| | +| ||| |+ || Sbjct 785 SGEKPYECNECGKCFILKKSLIGHQRIHTR#EKSYKCNDCGKVFSYRSNLIAHQRIHTGEK 844 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ | |+|||| || + ||| ||+#+| ||| |||||| || |+| |+ || Sbjct 701 NGEKPYECRECGKTFIMSKSFMVHQKLHTQ#EKAYKCEDCGKAFSYNSSLLVHRRIHTGEK 760 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 +|+ | | |||| | | + || ||+ || #+||||| +||| |++ | | | || |+ Sbjct 421 SGEKPYKCNECGKAFSQSAYLLNHQRIHTG#EKPYKCKECGKGFYRHSGLIIHLRRHSGER 480 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | +||||| || |+ ||+ || #+||| |++||| | +| ||| || || Sbjct 820 CNDCGKVFSYRSNLIAHQRIHTG#EKPYACNECGKGFTYNRNLIEHQRIHSGEK 872 Query 334 PCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | |||||||||+ || ||+ || #|| + | ||| | || |+| ||||| Sbjct 565 PYKCKECGKVFIRSKSLLLHQRVHTE#KKTFGCKKCGKIFTSKSSLIDHKRMHSREK 620 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 +|+ | | |||||| | + |+ ||+ | #++||||+ | ||| || ||| || || Sbjct 477 SGERPYKCNECGKVFSQNAYLIDHQRLHKG#EEPYKCNKCQKAFILKKSLILHQRIHSGEK 536 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 +|+ | | |||| | | + |+ ||+ |+ #+ |||| +||| | + || ||| |+ +| Sbjct 533 SGEKPYKCDECGKTFAQTTYLVDHQRLHST#ENPYKCKECGKVFIRSKSLLLHQRVHTEKK 592 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||+ | |+ |++ |+ #+|||+|++||| | || ||| |+||| Sbjct 757 TGEKPFECNECGRAFSSNRNLIEHKRIHSG#EKPYECNECGKCFILKKSLIGHQRIHTREK 816 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |||||| | + | |+ | + |+ #++||||++||| | | | ||| | |+ Sbjct 449 TGEKPYKCKECGKGFYRHSGLIIHLRRHSG#ERPYKCNECGKVFSQNAYLIDHQRLHKGEE 508 Query 331 GDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ | | +| | || + |+ ||+ |+ #+||||| +||| | | | ||| || | Sbjct 506 GEEPYKCNKCQKAFILKKSLILHQRIHSG#EKPYKCDECGKTFAQTTYLVDHQRLHSTEN 564 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | | |+ ||+ || #+|||+| | |+| +| ||| |+ || Sbjct 897 TGEKPYKCSECGKDFSQNKNLVVHQRMHTG#EKPYECEKCRKSFTSKRNLVGHQRIHTGEK 956 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ | | ||||||| + |+ ||+ || #+ |+| |||| | +| |+| |+ || Sbjct 645 NGEKPYECNECGKVFILKKSLILHQRFHTG#ENLYECKDCGKVFGSNRNLIDHERLHNGEK 704 Query 334 PCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | | |||| | | + | ||+ | #+|||+|++||| | || ||| |+ | Sbjct 621 PYKCTECGKAFTQSAYLFDHQRLHNG#EKPYECNECGKVFILKKSLILHQRFHTGEN 676 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |++||| | | || |++ || #+||++|++||+|| +| |+| || || Sbjct 736 CEDCGKAFSYNSSLLVHRRIHTG#EKPFECNECGRAFSSNRNLIEHKRIHSGEK 788 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ ||+||||| |+ |++ | #+|||+| +||| | | ||+ |++|| Sbjct 673 TGENLYECKDCGKVFGSNRNLIDHERLHNG#EKPYECRECGKTFIMSKSFMVHQKLHTQEK 732 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |++| | | + |+ ||+ || #+||| |+|| | | | +| ||+ |+ || Sbjct 925 TGEKPYECEKCRKSFTSKRNLVGHQRIHTG#EKPYGCNDCNKVFRQRKNLTVHQKIHTDEK 984 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | |+ ||+ |+ #+| |+|| | | +| ||| |+ || Sbjct 841 TGEKPYACNECGKGFTYNRNLIEHQRIHSG#EKTYECHVCRKVLTSSRNLMVHQRIHTGEK 900 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 +|+ | | || |+ ||+ || #+||||| +||| | | +| ||| |+ || Sbjct 869 SGEKTYECHVCRKVLTSSRNLMVHQRIHTG#EKPYKCSECGKDFSQNKNLVVHQRMHTGEK 928 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | | | | + | |+ |++ || #+||+|| +||| | | || | | || || Sbjct 372 CDMCYKHFNKISHLINHRRIHTG#EKPHKCKECGKGFIQRSSLLMHLRNHSGEK 424 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSRE 388 ||+ | | +| ||| || | ||| || #+| +| + | | | +| + || | Sbjct 953 TGEKPYGCNDCNKVFRQRKNLTVHQKIHTD#EKNCECDESEKEFSQTSNLHLQPKIHSLE 1011 |
| Homo sapiens | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | ||+||+ | ||| |+ |++||| #+|||+| +||||| | || ||+||| +| Sbjct 459 TGENPYECKQCGRAFSQRSSLVRHERTHTG#EKPYRCQECGKAFSQSSSLVTHQKTHSSQK 518 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | || | |++||| #+ ||+| ||+|| | || ||+|||+ || Sbjct 431 TGEKPYECSECGKAFSDRSSLNQHERTHTG#ENPYECKQCGRAFSQRSSLVRHERTHTGEK 490 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | + | | ||+ || #+||||| ||||+| | | |+|||+ || Sbjct 375 TGEKPYGCGECGKAFNRISSLTQHQRIHTG#EKPYKCEDCGKSFCQSSYLILHKRTHTGEK 434 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |++||| | | | |+ |++||| #+|||+| +||||| || +|+|||+ | Sbjct 403 TGEKPYKCEDCGKSFCQSSYLILHKRTHTG#EKPYECSECGKAFSDRSSLNQHERTHTGEN 462 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |+|||+ | | | | +||| #+||| | +||||| ++ || +||| |+ || Sbjct 347 TGEKPYECQECGRAFTHSSTLTRHLRTHTG#EKPYGCGECGKAFNRISSLTQHQRIHTGEK 406 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | + | | +||||| +| | ||+ || #+|||+| +||+|| +| || |||+ || Sbjct 319 TAEKPFECHQCGKVFNRRHSLSEHQRIHTG#EKPYECQECGRAFTHSSTLTRHLRTHTGEK 378 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQ 374 ||+ | |+|||| | | | |+||||||+ #+| || ||||||+| Sbjct 487 TGEKPYRCQECGKAFSQSSSLVTHQKTHSS#QKTYKIIDCGKAFYQ 531 Query 334 PCICKECGKVFIQRS-----------------------ELLTHQKTHTR#KKPYKCHDCGK 370 || ||| | | | | | +| #+||++|| ||| Sbjct 272 PCESNECGNAIRQNSHFIQHGGKMFVYLENGQSLNHGMALTIHNKINTA#EKPFECHQCGK 331 Query 371 AFFQMLSLFRHQRTHSREK 389 | + || ||| |+ || Sbjct 332 VFNRRHSLSEHQRIHTGEK 350 |
| Pan troglodytes | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | +| |||| | |+| |++||+||| #+|||+| +||||| + || |||||+ || Sbjct 510 TGEKPYVCSECGKAFCQKSHLISHQRTHTG#EKPYECSECGKAFGEKSSLATHQRTHTGEK 569 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | || +||| | ++|+|+ ||+||| #+|||+| +||||| + ||| ||| |+ || Sbjct 454 TGEKPFICSKCGKAFSRKSQLVRHQRTHTG#EKPYECSECGKAFSEKLSLTNHQRIHTGEK 513 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | ++| | |||+||| #+|||+| || ||| | | ||| |+ || Sbjct 538 TGEKPYECSECGKAFGEKSSLATHQRTHTG#EKPYECRDCEKAFSQKSQLNTHQRIHTGEK 597 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | +||| | |+|+| +||+||| #+|||+| +||||| + | | |||+ || Sbjct 258 TGEKPYNCSQCGKAFSQKSQLTSHQRTHTG#EKPYECGECGKAFSRKSHLISHWRTHTGEK 317 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |+|||| | ++|+|+|| +||| # ||+ | || ||||+ | ||| |+ || Sbjct 342 TGEKPFECRECGKAFSRKSQLVTHHRTHTG#TKPFGCSDCRKAFFEKSELIRHQTIHTGEK 401 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | ++| |++| +||| #+||| |++||+|| + +| ||| |+ || Sbjct 286 TGEKPYECGECGKAFSRKSHLISHWRTHTG#EKPYGCNECGRAFSEKSNLINHQRIHTGEK 345 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | || | | |+|+|+ ||+ || #+|||+| +||||| | | |||||+ +| Sbjct 678 TGEKPYGCSECRKAFSQKSQLVNHQRIHTG#EKPYRCIECGKAFSQKSQLINHQRTHTVKK 737 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | +||| | |+| |++|| ||| #+||+ | ||||| + | ||||||+ || Sbjct 426 TGEKPHGCIQCGKAFSQKSHLISHQMTHTG#EKPFICSKCGKAFSRKSQLVRHQRTHTGEK 485 Query 332 DIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 || | ||| | |+|+ +|| +||| #+||| | ||||| | | |||||+ || Sbjct 232 DIAFGCGNCGKTFPQKSQFITHHRTHTG#EKPYNCSQCGKAFSQKSQLTSHQRTHTGEK 289 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | ++| |+ ||+||| #+||| | +| ||| | | ||| |+ || Sbjct 650 TGEKPFECSECGKAFSRKSHLIPHQRTHTG#EKPYGCSECRKAFSQKSQLVNHQRIHTGEK 709 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||| | ++ | ||+ || #+||| | +||||| | | |||||+ || Sbjct 482 TGEKPYECSECGKAFSEKLSLTNHQRIHTG#EKPYVCSECGKAFCQKSHLISHQRTHTGEK 541 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | |++| | | |+|+| |||+ || #+|||+| | ||||+ | || |||+ || Sbjct 566 TGEKPYECRDCEKAFSQKSQLNTHQRIHTG#EKPYECSLCRKAFFEKSELIRHLRTHTGEK 625 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | || | | ++| |+ ||+ || #+||++| +||||| + | |||||+ || Sbjct 622 TGEKPYECNECRKAFREKSSLINHQRIHTG#EKPFECSECGKAFSRKSHLIPHQRTHTGEK 681 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 || | | +| | | ++|||+ || || #+|||+| +| ||| + || |||||+ || Sbjct 370 TGTKPFGCSDCRKAFFEKSELIRHQTIHTG#EKPYECSECRKAFRERSSLINHQRTHTGEK 429 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | || | | +|| |+ ||+||| #+||+ | ||||| | | || ||+ || Sbjct 398 TGEKPYECSECRKAFRERSSLINHQRTHTG#EKPHGCIQCGKAFSQKSHLISHQMTHTGEK 457 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | |||+ | ++| |+ ||+ || #+||++| +||||| + | | |||+ | Sbjct 314 TGEKPYGCNECGRAFSEKSNLINHQRIHTG#EKPFECRECGKAFSRKSQLVTHHRTHTGTK 373 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | | | | ++|||+ | +||| #+|||+|++| ||| + || ||| |+ || Sbjct 594 TGEKPYECSLCRKAFFEKSELIRHLRTHTG#EKPYECNECRKAFREKSSLINHQRIHTGEK 653 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | || | | ++ |+ || | |# + | +||| | | | |||+ || Sbjct 209 CSECRKRFSKKPSLIKHQSRHIR#DIAFGCGNCGKTFPQKSQFITHHRTHTGEK 261 |
| Rattus norvegicus | Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | || |||| | | + || ||| || #||||||++| | | | | |||| || || Sbjct 501 TGEKPYICNECGKTFSQSTHLLQHQKIHTG#KKPYKCNECWKVFSQSTYLIRHQRIHSGEK 560 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | +||| | ||+ | ||+ || #+|||||+|||| | | | |||||+ || Sbjct 417 TGEKPYECHQCGKAFSQRAHLTIHQRIHTG#EKPYKCNDCGKDFSQRAHLTIHQRTHTGEK 476 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | +||| | ||+ | ||+||| #+||||| +| | | || ||| |+ || Sbjct 445 TGEKPYKCNDCGKDFSQRAHLTIHQRTHTG#EKPYKCLECSKTFSHSSSLINHQRVHTGEK 504 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ || ||| | | + | | +||| #+||||| ||||| | + | +||| |+ || Sbjct 585 TGEKSYICNVCGKAFSQSANLTQHHRTHTG#EKPYKCSVCGKAFSQSVHLTQHQRIHNGEK 644 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+ | | ||| + | + | ||+ || #+|||||| ||||| || +|+|||+ |+ Sbjct 641 NGEKPFKCNTCGKAYRQGANLTQHQRVHTG#EKPYKCHHCGKAFIYSSSLNQHRRTHTGER 700 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 |+|||| | | |+ ||+ || #+|||+|| ||||| | | ||| |+ || Sbjct 396 CEECGKEFKHLSSLIAHQRMHTG#EKPYECHQCGKAFSQRAHLTIHQRIHTGEK 448 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | ||| | | | ||+ | #+||+||+ ||||+ | +| +||| |+ || Sbjct 613 TGEKPYKCSVCGKAFSQSVHLTQHQRIHNG#EKPFKCNTCGKAYRQGANLTQHQRVHTGEK 672 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | || | | | |+ ||+ || #+||| |++||| | | | +||+ |+ +| Sbjct 473 TGEKPYKCLECSKTFSHSSSLINHQRVHTG#EKPYICNECGKTFSQSTHLLQHQKIHTGKK 532 Query 337 CKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 | |||| | | |+ || ||| #+| | |+ ||||| | +| +| |||+ || Sbjct 564 CTECGKAFAHSSTLIQHQTTHTG#EKSYICNVCGKAFSQSANLTQHHRTHTGEK 616 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 ||+ | | ||| || | | |++||| #++|||| | | | | | +||| |+ |+ Sbjct 669 TGEKPYKCHHCGKAFIYSSSLNQHRRTHTG#ERPYKCTHCNKDFSQRTCLIQHQRIHTGER 728 Query 330 TGDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTH 385 ||+ | | | | | ||+ |+ ||+ || #++|| | |||+| | +| +||| | Sbjct 697 TGERPYKCTHCNKDFSQRTCLIQHQRIHTG#ERPYGCRICGKSFTQSTNLIQHQRVH 752 Query 331 GDIPCICKECGKVFIQRSELLTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 || | | ||| | + || |+ | +# | |+| +||| | + || ||| |+ || Sbjct 362 GDKPYSCNVCGKKFRKYPSLLAHRNNHAK#DKSYECEECGKEFKHLSSLIAHQRMHTGEK 420 Query 351 LTHQKTHTR#KKPYKCHDCGKAFFQMLSLFRHQRTHSREK 389 + | | # ||| |+ ||| | + || |+ |+++| Sbjct 354 VVHGKILPG#DKPYSCNVCGKKFRKYPSLLAHRNNHAKDK 392 |
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