XSB0044 : PREDICTED: filamin 1 (actin-binding protein-280) isoform 5 [Macaca mulatta]
[ CaMP Format ]
This entry is computationally expanded from SB0090
* Basic Information
| Organism | Macaca mulatta (rhesus monkey) |
| Protein Names | filamin 1 (actin-binding protein-280) isoform 5 |
| Gene Names | FLNA; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 12 mRNAs, 807 ESTs, 17 Proteins |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 2612 aa
Average Mass: 277.392 kDa
Monoisotopic Mass: 277.219 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| CH 1. | 17 | 122 | 108.9 | 1.7e-29 |
| CH 2. | 140 | 242 | 102.9 | 1.1e-27 |
| Filamin 1. | 251 | 344 | 108.6 | 2.1e-29 |
| Filamin 2. | 351 | 444 | 130.6 | 5e-36 |
| Filamin 3. | 450 | 540 | 133.0 | 9.3e-37 |
| Filamin 4. | 546 | 633 | 106.2 | 1.1e-28 |
| Filamin 5. | 642 | 733 | 148.4 | 2.2e-41 |
| Filamin 6. | 739 | 836 | 123.9 | 5.4e-34 |
| Filamin 7. | 842 | 935 | 129.4 | 1.1e-35 |
| Filamin 8. | 941 | 1031 | 102.8 | 1.2e-27 |
| Filamin 9. | 1037 | 1124 | 158.5 | 2e-44 |
| Filamin 10. | 1130 | 1219 | 134.1 | 4.5e-37 |
| Filamin 11. | 1225 | 1319 | 120.3 | 6.5e-33 |
| Filamin 12. | 1325 | 1412 | 151.8 | 2e-42 |
| Filamin 13. | 1418 | 1509 | 152.9 | 9.8e-43 |
| Filamin 14. | 1515 | 1606 | 147.1 | 5.4e-41 |
| Filamin 15. | 1612 | 1702 | 127.6 | 4.1e-35 |
| --- cleavage 1726 --- |
| Filamin 16. | 1738 | 1822 | 33.9 | 6.6e-07 |
| Filamin 17. | 1827 | 1914 | 156.7 | 6.8e-44 |
| Filamin 18. | 1915 | 2001 | 25.5 | 6.3e-05 |
| Filamin 19. | 2009 | 2096 | 146.4 | 8.8e-41 |
| Filamin 20. | 2115 | 2192 | 19.3 | 0.00023 |
| Filamin 21. | 2200 | 2287 | 139.8 | 8.6e-39 |
| Filamin 22. | 2294 | 2382 | 91.4 | 3.2e-24 |
| Filamin 23. | 2391 | 2478 | 127.9 | 3.3e-35 |
| Filamin 24. | 2519 | 2608 | 110.2 | 6.7e-30 |
3. Sequence Information
Fasta Sequence: XSB0044.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] LRSQQLAPQY1726-TYAQGGQQTW
Tyr1726 
Thr
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Leu1717 | Arg1718 | Ser1719 | Gln1720 | Gln1721 | Leu1722 | Ala1723 | Pro1724 | Gln1725 | Tyr1726 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Thr1727 | Tyr1728 | Ala1729 | Gln1730 | Gly1731 | Gly1732 | Gln1733 | Gln1734 | Thr1735 | Trp1736 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
PNSPFQVTALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDMTSLRPF
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Macaca mulatta |
127.00 |
5 |
PREDICTED: filamin 1 (actin-binding protein-280) i |
| 2 |
Homo sapiens |
126.00 |
13 |
filamin A |
| 3 |
Canis familiaris |
118.00 |
11 |
PREDICTED: similar to Filamin A (Alpha-filamin) (F |
| 4 |
Bos taurus |
114.00 |
1 |
PREDICTED: similar to filamin |
| 5 |
Mus musculus |
113.00 |
7 |
filamin, alpha |
| 6 |
N/A |
113.00 |
1 |
F |
| 7 |
Rattus norvegicus |
108.00 |
1 |
PREDICTED: similar to Filamin-A (Alpha-filamin) (F |
| 8 |
Tetraodon nigroviridis |
40.00 |
1 |
unnamed protein product |
| 9 |
Pan troglodytes |
38.90 |
2 |
PREDICTED: filamin B, beta (actin binding protein |
| 10 |
Danio rerio |
37.70 |
1 |
PREDICTED: similar to gamma-filamin |
| 11 |
Gallus gallus |
32.30 |
1 |
filamin |
Top-ranked sequences
| organism | matching |
|---|
| Macaca mulatta |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
|
| Homo sapiens |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
||||||||||||||||||||||||||||||#|||||||||||||||||||||||+||||||
Sbjct 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDVTSLRPF 1756
|
| Canis familiaris |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
|||||||||||||||+ ||||| ||||| |#||||||||||||||||+||||||+||||||
Sbjct 1732 PNSPFQVTALAGDQPAAQPPLRPQQLAPPY#TYAQGGQQTWAPERPLMGVNGLDVTSLRPF 1791
|
| Bos taurus |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
|||||||||||||||+ || || ||||| |#|||||||||||||||||||||||++|||||
Sbjct 2015 PNSPFQVTALAGDQPTAQPSLRPQQLAPPY#TYAQGGQQTWAPERPLVGVNGLDVSSLRPF 2074
|
| Mus musculus |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
|||||||||||||||+|| |||||||||||# | || |||| ||||+|||||||+||||||
Sbjct 1697 PNSPFQVTALAGDQPTVQTPLRSQQLAPQY#NYPQGSQQTWIPERPMVGVNGLDVTSLRPF 1756
|
| N/A |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
|||||||||||||||+|| |||||||||||# | || |||| ||||+|||||||+||||||
Sbjct 1732 PNSPFQVTALAGDQPTVQTPLRSQQLAPQY#NYPQGSQQTWIPERPMVGVNGLDVTSLRPF 1791
|
| Rattus norvegicus |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
|||||||||||||||+|| ||| ||| ||#|| || |||| ||||+|||||||+||||||
Sbjct 1732 PNSPFQVTALAGDQPTVQTPLRPQQLPSQY#TYPQGSQQTWIPERPMVGVNGLDVTSLRPF 1791
|
| Tetraodon nigroviridis |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTW----APERPLVGVNGLDMTS 1752
|||||||| | ++ | + + | #+++ | | +||+ |+||||+
Sbjct 1674 PNSPFQVTVSVGQIYTLNPWEKKDKNCKQE#SHSSIGNPLTSVPQATDRPM-GMNGLDVAG 1732
Query 1753 LRPF 1756
||||
Query 1753 LRPF 1756
|
| Pan troglodytes |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
||||| | | | | + | + + ++#|+ + | || | | |+ ++ +||
Sbjct 1696 PNSPFTVMGL-GQYPGLSPGILKDNSSEKH#TFMKTKQLTWVTEEAYVPVSNMNGLGFKPF 1754
|
| Danio rerio |
Query 1697 PNSPFQVTALAGDQPSVQPPLRSQQLAPQY#TYAQGGQQTWAPERPLVGVNGLDMTSLRPF 1756
||||| | | + | ++ | || |# || || | |+ |+ ++ ||||
Sbjct 1263 PNSPFHVVA-SDTIPIIEEPCDKLQLQQPY#APYQGYSPHWATEEPVTAVDIIEPV-LRPF 1320
|
| Gallus gallus |
Query 1734 QTWAPERPLVGVNGLDMTSLRPF 1756
| | ||||+||||||+ ||||
Sbjct 62 QVMATERPLLGVNGLDV-GLRPF 83
|
