XSB0112 : Plasma membrane calcium-transporting ATPase 2
[ CaMP Format ]
This entry is computationally expanded from SB0056
* Basic Information
| Organism | Rattus norvegicus (Norway rat) |
| Protein Names | PMCA2; Plasma membrane calcium ATPase isoform 2; Plasma membrane calcium pump isoform 2; 3.6.3.8 |
| Gene Names | Atp2b2 |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 1243 aa
Average Mass: 136.811 kDa
Monoisotopic Mass: 136.724 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Cation_ATPase_N 1. | 41 | 124 | 72.9 | 1.1e-18 |
| E1-E2_ATPase 1. | 156 | 489 | 220.9 | 3.2e-63 |
| Hydrolase 1. | 493 | 841 | 55.8 | 1.7e-13 |
| Cation_ATPase_C 1. | 902 | 1084 | 210.7 | 3.8e-60 |
3. Sequence Information
Fasta Sequence: XSB0112.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] GQILWFRGLN1135-RIQTQIRVVK
Asn1135 
Arg
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gly1126 | Gln1127 | Ile1128 | Leu1129 | Trp1130 | Phe1131 | Arg1132 | Gly1133 | Leu1134 | Asn1135 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Arg1136 | Ile1137 | Gln1138 | Thr1139 | Gln1140 | Ile1141 | Arg1142 | Val1143 | Val1144 | Lys1145 |
Sequence conservation (by blast)
* References
[PubMed ID: 2837461] Shull GE, Greeb J, Molecular cloning of two isoforms of the plasma membrane Ca2+-transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases. J Biol Chem. 1988 Jun 25;263(18):8646-57.