logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB0175 : microtubule-associated protein 2C [Homo sapiens]

[ CaMP Format ]

This entry is computationally expanded from SB0057

* Basic Information

OrganismHomo sapiens (human)
Protein NamesMicrotubule-associated protein 2; MAP-2; microtubule-associated protein 2C
Gene NamesMAP2
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAB48097 N/A N/A P11137 N/A N/A N/A hsa:

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 472 aa

Average Mass: 49.725 kDa

Monoisotopic Mass: 49.696 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
RII_binding_1 1. 8610319.20.017
--- cleavage 99 (inside RII_binding_1 86..103) ---
Drf_FH1 1. 135298-37.32.9
Tubulin-binding 1. 30533664.34.4e-16
Tubulin-binding 2. 33736766.01.4e-16
Tubulin-binding 3. 36839955.12.6e-13

3. Sequence Information

Fasta Sequence: XSB0175.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] VSARIVQVVT99-AEAVAVLKGE

Thr99 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Val90Ser91Ala92Arg93Ile94Val95Gln96Val97Val98Thr99
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala100Glu101Ala102Val103Ala104Val105Leu106Lys107Gly108Glu109

Sequence conservation (by blast)

* References

[PubMed ID: 8294038] Albala JS, Kalcheva N, Shafit-Zagardo B, Characterization of the transcripts encoding two isoforms of human microtubule-associated protein-2 (MAP-2). Gene. 1993 Dec 22;136(1-2):377-8.