logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB0227 : c-jun oncogene

[ CaMP Format ]

This entry is computationally expanded from SB0086

* Basic Information

OrganismHomo sapiens (human)
Protein NamesNot available
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
1404381A N/A N/A N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 330 aa

Average Mass: 35.547 kDa

Monoisotopic Mass: 35.525 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Jun 1. 5241447.52e-131
--- cleavage 164 (inside Jun 5..241) ---
--- cleavage 42 (inside Jun 5..241) ---
--- cleavage 90 (inside Jun 5..241) ---
--- cleavage 62 (inside Jun 5..241) ---
bZIP_1 1. 25031384.92.9e-22

3. Sequence Information

Fasta Sequence: XSB0227.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

4 [sites]

Cleavage sites (±10aa)

[Site 1] GSGGFSASLH164-SEPPVYANLS

His164 Ser

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gly155Ser156Gly157Gly158Phe159Ser160Ala161Ser162Leu163His164
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ser165Glu166Pro167Pro168Val169Tyr170Ala171Asn172Leu173Ser174

Sequence conservation (by blast)

[Site 2] ILKQSMTLNL42-ADPVGSLKPH

Leu42 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ile33Leu34Lys35Gln36Ser37Met38Thr39Leu40Asn41Leu42
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala43Asp44Pro45Val46Gly47Ser48Leu49Lys50Pro51His52

Sequence conservation (by blast)

[Site 3] IQSSNGHITT90-TPTPTQFLCP

Thr90 Thr

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ile81Gln82Ser83Ser84Asn85Gly86His87Ile88Thr89Thr90
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Thr91Pro92Thr93Pro94Thr95Gln96Phe97Leu98Cys99Pro100

Sequence conservation (by blast)

[Site 4] LRAKNSDLLT62-SPDVGLLKLA

Thr62 Ser

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Leu53Arg54Ala55Lys56Asn57Ser58Asp59Leu60Leu61Thr62
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ser63Pro64Asp65Val66Gly67Leu68Leu69Lys70Leu71Ala72

Sequence conservation (by blast)

* References

[PubMed ID: 3347253] Angel P, Allegretto EA, Okino ST, Hattori K, Boyle WJ, Hunter T, Karin M, Oncogene jun encodes a sequence-specific trans-activator similar to AP-1. Nature. 1988 Mar 10;332(6160):166-71.