logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB0233 : talin

[ CaMP Format ]

This entry is computationally expanded from SB0081

* Basic Information

OrganismMus musculus (house mouse)
Protein NamesNot available
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
1617167A N/A N/A N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 2541 aa

Average Mass: 269.833 kDa

Monoisotopic Mass: 269.665 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
FERM_N 1. 90199101.23.5e-27
FERM_M 1. 201313144.72.8e-40
--- cleavage 433 ---
Talin_middle 1. 491652372.57.7e-109
Stork_head 1. 728795-14.03.2
Inhibitor_I34 1. 840905-11.37.9
CRA_rpt 1. 907945-6.08.2
CMD 1. 9771059-15.18.7
DUF1707 1. 11601204-25.04.3
XhlA 1. 13601411-17.36.8
Mucin 1. 14761614-38.29
DUF1657 1. 16601717-15.39.3
HHH 1. 180518340.16.9
VBS 1. 18491973288.81.2e-83
Vir_act_alpha_C 1. 21842262-17.00.85
Wos2 1. 22772322-3.63.1
I_LWEQ 1. 23412533372.57.7e-109

3. Sequence Information

Fasta Sequence: XSB0233.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] VSPKKSTVLQ433-QQYNRVGKVE

Gln433 Gln

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Val424Ser425Pro426Lys427Lys428Ser429Thr430Val431Leu432Gln433
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gln434Gln435Tyr436Asn437Arg438Val439Gly440Lys441Val442Glu443

Sequence conservation (by blast)

* References

[PubMed ID: 2120593] Rees DJ, Ades SE, Singer SJ, Hynes RO, Sequence and domain structure of talin. Nature. 1990 Oct 18;347(6294):685-9.