logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB0498 : Major intrinsic protein of eye lens fiber [Mus musculus]

[ CaMP Format ]

This entry is computationally expanded from SB0003

* Basic Information

OrganismMus musculus (house mouse)
Protein Namesmajor intrinsic protein of eye lens fiber
Gene NamesMip
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAH82567 N/A 17339 Q640N8 N/A N/A N/A mmu:17339

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 263 aa

Average Mass: 28.207 kDa

Monoisotopic Mass: 28.189 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
MIP 1. 3219416.73.7e-122

3. Sequence Information

Fasta Sequence: XSB0498.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] SVSERLSILK238-GARPSDSNGQ

Lys238 Gly

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ser229Val230Ser231Glu232Arg233Leu234Ser235Ile236Leu237Lys238
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gly239Ala240Arg241Pro242Ser243Asp244Ser245Asn246Gly247Gln248

Sequence conservation (by blast)

* References

[PubMed ID: 12477932] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.