XSB0629 : protein kinase C, alpha variant [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0055
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | Protein kinase C, alpha variant; protein kinase C; alpha variant |
| Gene Names | Not available |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 461 aa
Average Mass: 52.976 kDa
Monoisotopic Mass: 52.941 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| C1_1 1. | 13 | 65 | 92.5 | 1.5e-24 |
| C2 1. | 84 | 171 | 137.9 | 3.3e-38 |
| --- cleavage 235 --- | ||||
| --- cleavage 227 --- | ||||
| --- cleavage 220 --- | ||||
| Pkinase 1. | 250 | 460 | 186.5 | 7.3e-53 |
3. Sequence Information
Fasta Sequence: XSB0629.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
3 [sites]
Cleavage sites (±10aa)
[Site 1] NKVISPSEDR235-KQPSNNLDRV
Arg235 
Lys
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Asn226 | Lys227 | Val228 | Ile229 | Ser230 | Pro231 | Ser232 | Glu233 | Asp234 | Arg235 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Lys236 | Gln237 | Pro238 | Ser239 | Asn240 | Asn241 | Leu242 | Asp243 | Arg244 | Val245 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| EEGNMELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVM |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 122.00 | 24 | protein kinase C, alpha variant |
| 2 | N/A | 122.00 | 17 | - |
| 3 | Mus musculus | 122.00 | 11 | protein kinase C |
| 4 | synthetic construct | 122.00 | 4 | protein kinase C alpha |
| 5 | Rattus norvegicus | 121.00 | 8 | PREDICTED: similar to Protein kinase C alpha type |
| 6 | Canis familiaris | 120.00 | 13 | PREDICTED: similar to Protein kinase C, alpha type |
| 7 | Bos taurus | 120.00 | 7 | protein kinase C, alpha |
| 8 | Oryctolagus cuniculus | 120.00 | 6 | KPCA_RABIT Protein kinase C alpha type (PKC-alpha) |
| 9 | Gallus gallus | 109.00 | 7 | protein kinase C, alpha |
| 10 | Monodelphis domestica | 109.00 | 6 | PREDICTED: similar to protein kinase C |
| 11 | Latimeria chalumnae | 106.00 | 2 | protein kinase C alpha |
| 12 | Xenopus tropicalis | 100.00 | 3 | hypothetical protein LOC780209 |
| 13 | Xenopus laevis | 96.30 | 2 | protein kinase C, alpha |
| 14 | Protopterus dolloi | 92.00 | 2 | protein kinase C alpha |
| 15 | Takifugu rubripes | 80.90 | 1 | protein kinase C, alpha type |
| 16 | Scyliorhinus canicula | 76.60 | 2 | protein kinase C alpha |
| 17 | Danio rerio | 76.30 | 14 | protein kinase C, beta 1 |
| 18 | Tetraodon nigroviridis | 74.30 | 5 | unnamed protein product |
| 19 | Macaca mulatta | 67.40 | 15 | PREDICTED: protein kinase C, beta 1 isoform 4 |
| 20 | Petromyzon marinus | 67.00 | 1 | protein kinase C |
| 21 | Myxine glutinosa | 55.50 | 1 | protein kinase C |
| 22 | Macaca fascicularis | 50.10 | 4 | KPCG_MACFA Protein kinase C gamma type (PKC-gamma) |
| 23 | Branchiostoma lanceolatum | 49.30 | 1 | protein kinase C |
| 24 | Bombyx mori | 47.80 | 1 | conventional protein kinase C |
| 25 | Aplysia californica | 47.00 | 2 | KPC2_APLCA Calcium-independent protein kinase C (A |
| 26 | Apis mellifera | 46.20 | 2 | PREDICTED: similar to Protein C kinase 53E CG6622- |
| 27 | Anopheles gambiae str. PEST | 45.40 | 3 | ENSANGP00000009078 |
| 28 | Aedes aegypti | 45.40 | 2 | protein kinase c |
| 29 | Drosophila melanogaster | 44.30 | 8 | unnamed protein product |
| 30 | Tribolium castaneum | 42.00 | 3 | PREDICTED: similar to CG6622-PA, isoform A |
| 31 | Drosophila pseudoobscura | 41.20 | 3 | GA19732-PA |
| 32 | Caenorhabditis briggsae | 41.20 | 1 | Hypothetical protein CBG16150 |
| 33 | Coprinopsis cinerea okayama7#130 | 41.20 | 1 | hypothetical protein CC1G_07190 |
| 34 | Magnaporthe grisea 70-15 | 41.20 | 1 | hypothetical protein MGG_08689 |
| 35 | Magnaporthe grisea | 40.80 | 1 | AF136600_1 protein kinase C |
| 36 | Caenorhabditis elegans | 40.40 | 5 | protein kinase C2 A isoform |
| 37 | Strongylocentrotus purpuratus | 40.40 | 4 | PREDICTED: similar to protein kinase C |
| 38 | Pan troglodytes | 39.70 | 4 | PREDICTED: serum/glucocorticoid regulated kinase 3 |
| 39 | Botryotinia fuckeliana | 39.70 | 1 | protein kinase C |
| 40 | Paramecium tetraurelia | 39.70 | 1 | hypothetical protein |
| 41 | Schizosaccharomyces pombe | 39.30 | 3 | SPAC17G8.14c |
| 42 | Schizosaccharomyces pombe 972h- | 39.30 | 2 | hypothetical protein SPAC17G8.14c |
| 43 | Hydractinia echinata | 39.30 | 1 | putative calcium dependent protein kinase C |
| 44 | Leptosphaeria maculans | 38.90 | 1 | AF487263_9 protein kinase C |
| 45 | Yarrowia lipolytica | 38.90 | 1 | hypothetical protein |
| 46 | Tuber excavatum | 38.50 | 2 | protein kinase C-like protein |
| 47 | Suberites domuncula | 38.50 | 2 | Serine/Threonine protein kinase |
| 48 | Calliphora vicina | 38.50 | 1 | eye-specific protein kinase C |
| 49 | Asparagus officinalis | 38.50 | 1 | S6 ribosomal protein kinase |
| 50 | Tuber aestivum | 38.10 | 2 | protein kinase C-like protein |
| 51 | Sycon raphanus | 38.10 | 1 | Serine/Threonine protein kinase |
| 52 | Cryptococcus neoformans var. neoformans JEC21 | 37.70 | 1 | protein kinase C |
| 53 | Cryptococcus neoformans var. neoformans | 37.70 | 1 | protein kinase C 1 |
| 54 | Squalus acanthias | 37.70 | 1 | s-sgk1 |
| 55 | Cryptococcus neoformans var. neoformans B-3501A | 37.70 | 1 | hypothetical protein CNBC3910 |
| 56 | Cryptococcus neoformans var. grubii | 37.70 | 1 | protein kinase C 1 |
| 57 | Tuber indicum | 37.00 | 6 | protein kinase C-like protein |
| 58 | Phaeosphaeria nodorum SN15 | 37.00 | 2 | hypothetical protein SNOG_13609 |
| 59 | Tuber pseudoexcavatum | 37.00 | 2 | protein kinase C-like protein |
| 60 | Leishmania braziliensis | 37.00 | 1 | zinc finger protein kinase-like |
| 61 | Aspergillus clavatus NRRL 1 | 36.60 | 1 | protein kinase c |
| 62 | Debaryomyces hansenii CBS767 | 36.60 | 1 | hypothetical protein DEHA0G14773g |
| 63 | Cochliobolus heterostrophus | 36.60 | 1 | KPC1_COCHE Protein kinase C-like emb |
| 64 | Plasmodium berghei strain ANKA | 36.60 | 1 | rac-beta serine/threonine protein kinase |
| 65 | Ashbya gossypii ATCC 10895 | 36.60 | 1 | ACR191Cp |
| 66 | Aspergillus oryzae | 36.60 | 1 | unnamed protein product |
| 67 | Candida albicans | 36.60 | 1 | KPC1_CANAL Protein kinase C-like 1 (PKC 1) emb |
| 68 | Sporothrix schenckii | 36.60 | 1 | AF124792_1 protein kinase C; serine/threonine prot |
| 69 | Hydra vulgaris | 36.20 | 2 | protein kinase C |
| 70 | Coccidioides immitis RS | 36.20 | 1 | hypothetical protein CIMG_09206 |
| 71 | Plasmodium yoelii yoelii str. 17XNL | 36.20 | 1 | hypothetical protein PY00403 |
| 72 | Neosartorya fischeri NRRL 181 | 36.20 | 1 | protein kinase c |
| 73 | Aspergillus terreus NIH2624 | 36.20 | 1 | hypothetical protein ATEG_02078 |
| 74 | Medicago truncatula | 36.20 | 1 | Protein kinase |
| 75 | Blumeria graminis | 35.80 | 1 | AF247001_1 protein kinase C |
| 76 | Fundulus heteroclitus | 35.80 | 1 | serum and glucocorticoid-regulated kinase |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |
| N/A | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |
| Mus musculus | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |
| synthetic construct | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |
| Rattus norvegicus | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ||||+|||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 235 EEGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 294 |
| Canis familiaris | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ||||+|||||||||||||||||||||||||#+||||||||||||||||||||||||||||| Sbjct 213 EEGNVELRQKFEKAKLGPAGNKVISPSEDR#RQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 272 |
| Bos taurus | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ||||+|||||||||||||||||||||||||#+||||||||||||||||||||||||||||| Sbjct 295 EEGNVELRQKFEKAKLGPAGNKVISPSEDR#RQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Oryctolagus cuniculus | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |+||+|||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Gallus gallus | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 263 |+|| |||||||||||||||||||+|||||# |||||||||||||||||||||||||| Sbjct 295 EDGNAELRQKFEKAKLGPAGNKVITPSEDR#NSSVPSNNLDRVKLTDFNFLMVLGKGSFGK 354 Query 264 VM 265 || Query 264 VM 265 |
| Monodelphis domestica | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |||||||||||||||||| |||||| |+||#| |+|||||||||||||||||||||||||| Sbjct 295 EEGNMELRQKFEKAKLGPVGNKVISSSDDR#K-PTNNLDRVKLTDFNFLMVLGKGSFGKVM 353 |
| Latimeria chalumnae | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 263 ++||+|||||||||||||||+||||| |+|#| |||||||||||||||||||||||||| Sbjct 216 DDGNVELRQKFEKAKLGPAGSKVISPVEER#KSSTPSNNLDRVKLTDFNFLMVLGKGSFGK 275 Query 264 VM 265 || Query 264 VM 265 |
| Xenopus tropicalis | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 263 ++||+|||||||||||||||||||||+++|#+ ||||+| |+||||+|||||||||||| Sbjct 299 DDGNIELRQKFEKAKLGPAGNKVISPTDER#RPYVPSNNIDSVRLTDFSFLMVLGKGSFGK 358 Query 264 VM 265 || Query 264 VM 265 |
| Xenopus laevis | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 263 ++||+|||||||||||||||||||+|+ +|#+ ||||+| ++|||| |||||||||||| Sbjct 298 DDGNLELRQKFEKAKLGPAGNKVINPTGER#RPYIPSNNIDSIRLTDFCFLMVLGKGSFGK 357 Query 264 VM 265 || Query 264 VM 265 |
| Protopterus dolloi | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ++||+ ||||||||+||||| ||||| # | ||||| || ||||+|||||||||||| Sbjct 214 DDGNVGLRQKFEKARLGPAGKKVISPERKS#SLPLNNLDRFKLEDFNFVMVLGKGSFGKVM 273 |
| Takifugu rubripes | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#K--QPSNNLDRVKLTDFNFLMVLGKGSFGK 263 ++ |+|||||||||||| | |||+||+ |#+ || |+|||+| ||||| +|||||||| Sbjct 292 DDVNLELRQKFEKAKLGQ-GKKVITPSDHR#RFSLPSGNMDRVRLNDFNFLALLGKGSFGK 350 Query 264 VM 265 || Query 264 VM 265 |
| Scyliorhinus canicula | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ++ + |||+||||||||||| | | # |+|+|| | | ||||||||||||||||| Sbjct 226 DDEDSELRKKFEKAKLGPAGKKAIEKKPS-#-SPTNDLDHVHLEDFNFLMVLGKGSFGKVM 283 |
| Danio rerio | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSN-NLDRVKLTDFNFLMVLGKGSFGKV 264 |||| |||||||+||+||+ | + #| || | ||+||+|||||||||||||||| Sbjct 294 EEGNEELRQKFERAKIGPSKTDGSSSNAIS#KFDSNGNRDRMKLSDFNFLMVLGKGSFGKV 353 Query 265 M 265 | Query 265 M 265 |
| Tetraodon nigroviridis | Query 206 EEGNMELRQKFEKAKLGPAGNK--VISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGK 263 |||| |||||||+||+|| | + + |# + | ||+|| ||||||||||||||| Sbjct 231 EEGNEELRQKFERAKIGPGKNTDGKSANAASR#FDSNGNQDRMKLADFNFLMVLGKGSFGK 290 Query 264 VM 265 || Query 264 VM 265 |
| Macaca mulatta | Query 207 EGNMELRQKFEKAKLGPAGNKVISPSE------DR#KQPSNNLDRVKLTDFNFLMVLGKGS 260 ||| |||||||+||+ | || | | +# + | ||+||||||||||||||| Sbjct 167 EGNEELRQKFERAKISQ-GTKV--PEEKTTNTVSK#FDNNGNRDRMKLTDFNFLMVLGKGS 223 Query 261 FGKVM 265 ||||| Query 261 FGKVM 265 |
| Petromyzon marinus | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSN---------NLDRVKLTDFNFLMVL 256 |+|+ |+|+|||||+|||+ + | #++ +| |+|||| |||||||| Sbjct 225 EDGDTEMRRKFEKARLGPS----VKPRASD#ERRANSLSAILNNANVDRVKADDFNFLMVL 280 Query 257 GKGSFGKVM 265 ||||||||| Query 257 GKGSFGKVM 265 |
| Myxine glutinosa | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPS---NNLDRVKLTDFNFLMVLGKGSFG 262 ||| +||||+ +++++ + ||++|+# | + |||| | || || |||||||| Sbjct 216 EEG-LELRQRLQRSQIARSDKNKQSPAKDQ#PSDSASLSGLDRVNLEDFVFLTVLGKGSFG 274 Query 263 KVM 265 ||| Query 263 KVM 265 |
| Macaca fascicularis | Query 216 FEKAKLGPAGNKVISPSEDR#KQPSN-----NLDRVKLTDFNFLMVLGKGSFGKVM 265 +|+ ++||+ + + ||| # | + |+ ++||+|||||||||||||| Sbjct 312 YERVRMGPSSSPIPSPSPSP#TDPKRCFFGASPGRLHISDFSFLMVLGKGSFGKVM 366 |
| Branchiostoma lanceolatum | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 || +|++ +| || + ||+ # | || +| ||||||||||||||||| Sbjct 225 EENVAKLKEHLQKQKLDEQRKQKSKRSEEC#NIGS--LDHMKAADFNFLMVLGKGSFGKVM 282 |
| Bombyx mori | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGK 263 ||| +| | + + | + | ||#+ | | | ++ |||||+|||||||||| Sbjct 295 EEG-ADLVQLKNQMRATTVGARRPPPPPDR#EVPHNVAAADVIRATDFNFIMVLGKGSFGK 353 Query 264 VM 265 || Query 264 VM 265 |
| Aplysia californica | Query 225 GNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |++ ||| ||# + ++ |+ | ||||+ ||||||||||| Sbjct 380 GSRTRSPSSDR#SRSHHS--RISLHDFNFIKVLGKGSFGKVM 418 |
| Apis mellifera | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGK 263 ||| | + + + | + ++|+#+ | | | ++ +||||||||||||||| Sbjct 309 EEGVDLAELKMKPSPQKTSVTKKTTTTQDK#EVPHNMGKSDLIRASDFNFLMVLGKGSFGK 368 Query 264 VM 265 || Query 264 VM 265 |
| Anopheles gambiae str. PEST | Query 206 EEGN--MELRQKFEKAKLGPAGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSF 261 ||| ++|+ + | + | | |+# | | | ++ |||||||||||||| Sbjct 232 EEGADLVQLKSQMRKTSI----TKKIPMMGDK#DVPHNMTKKDVIRATDFNFLMVLGKGSF 287 Query 262 GKVM 265 |||| Query 262 GKVM 265 |
| Aedes aegypti | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ||| ++ | + | + + +| # | ++ |||||||||||||||||| Sbjct 240 EEGTDLVQLKSQMRKTSISKKAPVLCDKDV#PHNMGKKDVIRATDFNFLMVLGKGSFGKVM 299 |
| Drosophila melanogaster | Query 214 QKFEKAKLGPAGNK-VISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | | | |+ | ++ |+ # |+ | ++ |||||+ ||||||||||+ Sbjct 304 QDLLKLKQKPSQKKPMVMRSDTN#THTSSKKDMIRATDFNFIKVLGKGSFGKVL 356 |
| Tribolium castaneum | Query 235 R#KQPSNN--LDRVKLTDFNFLMVLGKGSFGKVM 265 +#++|| + | ++ +||||||||||||||||| Sbjct 320 Q#RRPSQHGQKDIIRASDFNFLMVLGKGSFGKVM 352 |
| Drosophila pseudoobscura | Query 214 QKFEKAKLGPAGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGKVM 265 | | | |+ | + | # |+ | ++ |||||+ ||||||||||+ Sbjct 190 QDLLKLKQKPSQKKPLVMRSDT#NTHSSISKKDMIRATDFNFIKVLGKGSFGKVL 243 |
| Caenorhabditis briggsae | Query 239 SNNLDRVKLTDFNFLMVLGKGSFGKVM 265 + | | +| +||||| ||||||||||+ Sbjct 404 NTNRDVIKASDFNFLTVLGKGSFGKVL 430 |
| Coprinopsis cinerea okayama7#130 | Query 217 EKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ++ + | + + ++ +#+||| +| | ||||| |||||+||||| Sbjct 685 QQGMVPPQHQQQMIQAQPQ#RQPSKKR-KVGLDDFNFLAVLGKGNFGKVM 732 |
| Magnaporthe grisea 70-15 | Query 213 RQKFEKAKLGPAGNKVISPSEDR#KQPS----NNLDRVKLTDFNFLMVLGKGSFGKVM 265 +| |+ + | || | |# || |+ | |||| |||||+||||| Sbjct 816 QQHQEQQIISPTAGTVIPTSAKR#PLPSATDPGTGQRIGLDHFNFLAVLGKGNFGKVM 872 |
| Magnaporthe grisea | Query 213 RQKFEKAKLGPAGNKVISPSEDR#KQPS----NNLDRVKLTDFNFLMVLGKGSFGKVM 265 +| |+ + | || | |# || |+ | |||| |||||+||||| Sbjct 816 QQHQEQQIISPTAGTVIPTSARR#PLPSATDPGTGQRIGLDHFNFLAVLGKGNFGKVM 872 |
| Caenorhabditis elegans | Query 239 SNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |+| + +| +||||| ||||||||||+ Sbjct 337 SSNHNVIKASDFNFLTVLGKGSFGKVL 363 |
| Strongylocentrotus purpuratus | Query 232 SEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | # ++++ |+ +||||| ||||||||||| Sbjct 307 SSQN#SNSNSSMGLVRASDFNFLSVLGKGSFGKVM 340 |
| Pan troglodytes | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | + +| + |||+|| | # |||+|| |+||||||||+ Sbjct 134 ERSSQKLHSTSQNINLGPSGNPHAKP----#------------TDFDFLKVIGKGSFGKVL 177 |
| Botryotinia fuckeliana | Query 223 PAGNKVISPSEDR#KQPSNNLD-----RVKLTDFNFLMVLGKGSFGKVM 265 | +|+ + |#|| | |+ | |||| |||||+||||| Sbjct 813 PGSQQVVPQGQQR#KQVPAANDAGTGRRIGLDHFNFLAVLGKGNFGKVM 860 |
| Paramecium tetraurelia | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 +|| ++ +| || ++ | # | |||||| | |||+||||||| Sbjct 32 KEGEQQMNDEFMKAPTATF-EQIEETGEQV#FVDDNREAIVKLTDFQFEKVLGRGSFGKVM 90 |
| Schizosaccharomyces pombe | Query 231 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | |#++ | || | || || |||||+||||| Sbjct 556 PESPR#REKKN---RVTLDDFTFLAVLGKGNFGKVM 587 |
| Schizosaccharomyces pombe 972h- | Query 231 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | |#++ | || | || || |||||+||||| Sbjct 648 PESPR#REKKN---RVTLDDFTFLAVLGKGNFGKVM 679 |
| Hydractinia echinata | Query 243 DRVKLTDFNFLMVLGKGSFGKVM 265 +|+|| || || |+||||||||| Sbjct 191 ERLKLEDFTFLKVIGKGSFGKVM 213 |
| Leptosphaeria maculans | Query 210 MELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLD----RVKLTDFNFLMVLGKGSFGKVM 265 | +| |++ |+ + |++# || | |+ | |||| |||||+||||| Sbjct 816 MSQKQPEAIAQIPPSKQLPPANPENK#VTPSANTQGSGKRIGLDHFNFLAVLGKGNFGKVM 875 |
| Yarrowia lipolytica | Query 219 AKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | || |+ | +#|+| |+ | ||||| |||||+||||| Sbjct 900 ASPAPASNRH-SVVGKK#KRP-----RIGLDDFNFLAVLGKGNFGKVM 940 |
| Tuber excavatum | Query 231 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |+ + #+|| ++ | |||| |||||+||||| Sbjct 312 PAPEP#QQPVIRPAKIGLDHFNFLAVLGKGNFGKVM 346 |
| Suberites domuncula | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSN------NLDRVKLTDFNFLMVLGKG 259 +| +| ++| || + +++ #++ | ++ ++|| ||| |+||||| Sbjct 293 DEEATKLIEEFRKATILDKAKNLVTDVPIM#RRGSELVPGAKDMPKMKLEDFNLLVVLGKG 352 Query 260 SFGKV 264 ||||| Query 260 SFGKV 264 |
| Calliphora vicina | Query 231 PSEDR#KQPSNNL---DRVKLTDFNFLMVLGKGSFGKVM 265 | | #| +|+ | ++ ||||+ ||||||+||++ Sbjct 333 PRIDN#KDMPHNMSKRDMIRAADFNFIKVLGKGSYGKIL 370 |
| Asparagus officinalis | Query 232 SEDR#KQPSN-NLDRVKLTDFNFLMVLGKGSFGKV 264 +|+ #+ ||+ |++|| | ||+|| |+|+|+|||| Sbjct 106 AEEH#EVPSSENVERVGLEDFDFLKVVGQGAFGKV 139 |
| Tuber aestivum | Query 231 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |+ + #+ | + ++ | |||| |||||+||||| Sbjct 314 PAPEP#QPPVSRPTKIGLDHFNFLAVLGKGNFGKVM 348 |
| Sycon raphanus | Query 246 KLTDFNFLMVLGKGSFGKVM 265 ||+||+|| ||||||||||| Sbjct 362 KLSDFSFLKVLGKGSFGKVM 381 |
| Cryptococcus neoformans var. neoformans JEC21 | Query 244 RVKLTDFNFLMVLGKGSFGKVM 265 +| | ||||| |||||+||||| Sbjct 751 KVGLDDFNFLAVLGKGNFGKVM 772 |
| Cryptococcus neoformans var. neoformans | Query 244 RVKLTDFNFLMVLGKGSFGKVM 265 +| | ||||| |||||+||||| Sbjct 751 KVGLDDFNFLAVLGKGNFGKVM 772 |
| Squalus acanthias | Query 238 PSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ||+| + | +||||| |+||||||||+ Sbjct 89 PSSN-PQAKPSDFNFLKVIGKGSFGKVL 115 |
| Cryptococcus neoformans var. neoformans B-3501A | Query 244 RVKLTDFNFLMVLGKGSFGKVM 265 +| | ||||| |||||+||||| Sbjct 754 KVGLDDFNFLAVLGKGNFGKVM 775 |
| Cryptococcus neoformans var. grubii | Query 244 RVKLTDFNFLMVLGKGSFGKVM 265 +| | ||||| |||||+||||| Sbjct 751 KVGLDDFNFLAVLGKGNFGKVM 772 |
| Tuber indicum | Query 231 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |+ + #+| + ++ | |||| |||||+||||| Sbjct 313 PAPEP#QQVVSKPTKIGLDHFNFLAVLGKGNFGKVM 347 |
| Phaeosphaeria nodorum SN15 | Query 240 NNLDRVKLTDFNFLMVLGKGSFGKVM 265 | ||+ + || | |+||||||||| Sbjct 273 NRQDRLSIDDFELLKVVGKGSFGKVM 298 |
| Tuber pseudoexcavatum | Query 231 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |+ + #+| + ++ | |||| |||||+||||| Sbjct 312 PAPEP#QQVVSKPTKIGLDHFNFLAVLGKGNFGKVM 346 |
| Leishmania braziliensis | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | | + +|+ + + ++|| # |+|| | | || | |+|+|+||||+ Sbjct 591 ESGQVMQQQRVINSTSPIPYSSLLSPRGSL#VSRSDNLSPVGLQDFQLLTVIGRGTFGKVL 650 |
| Aspergillus clavatus NRRL 1 | Query 223 PAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | +| | #+|| |+ | |||| |||||+||||| Sbjct 763 PMQQQVAVKEEVP#QQPKA---RIGLDHFNFLSVLGKGNFGKVM 802 |
| Debaryomyces hansenii CBS767 | Query 237 QPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 +| ++ | || || |||||+||||| Sbjct 750 KPKRRRRKIGLDDFQFLAVLGKGNFGKVM 778 |
| Cochliobolus heterostrophus | Query 221 LGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 +| | ++|+ + #+ |+ | |||| |||||+||||| Sbjct 823 VGEVPGKKVTPAANT#QGTGK---RIGLDHFNFLAVLGKGNFGKVM 864 |
| Plasmodium berghei strain ANKA | Query 209 NMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |+ + +||+| | | | +#|+ |+| +|||| |+||||+|||+ Sbjct 259 NLYIHDMYEKSKKKRL-RKFIPLSNKK#KR------RIKPDNFNFLKVIGKGSYGKVL 308 |
| Ashbya gossypii ATCC 10895 | Query 210 MELRQKFEKAKLGPAGNKVISPSEDR-#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 || + | | | + + |+ | #|+ + +| | || | |||||+||||+ Sbjct 781 MESIPQHPPAPLSPPKAQPVQPASGRH#KRKTPKRRKVSLDDFILLKVLGKGNFGKVL 837 |
| Aspergillus oryzae | Query 223 PAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | + ++ || # | |+ | |||| |||||+||||| Sbjct 741 PVMQQQVAMKEDA#P-PQQPKVRIGLDHFNFLAVLGKGNFGKVM 782 |
| Candida albicans | Query 206 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ++ | +++| ++ +|| | #|+ +| | || || |||||+||||| Sbjct 729 KQQNQQVQQVQQQEELGHQRTHSSGKSGKS#KRRKR---KVGLDDFQFLAVLGKGNFGKVM 785 |
| Sporothrix schenckii | Query 244 RVKLTDFNFLMVLGKGSFGKVM 265 |+ | +|||| |||||+||||| Sbjct 863 RIGLDNFNFLAVLGKGNFGKVM 884 |
| Hydra vulgaris | Query 246 KLTDFNFLMVLGKGSFGKVM 265 || || || |+||||||||| Sbjct 338 KLEDFTFLKVIGKGSFGKVM 357 |
| Coccidioides immitis RS | Query 244 RVKLTDFNFLMVLGKGSFGKVM 265 || | |||| |||||+||||| Sbjct 740 RVGLDHFNFLAVLGKGNFGKVM 761 |
| Plasmodium yoelii yoelii str. 17XNL | Query 211 ELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 ++ +| +| +| | | | +#|+ ||| +|||| |+||||+|||+ Sbjct 370 DMHEKSKKKRL----RKFIPLSNKK#KR------RVKPDNFNFLKVIGKGSYGKVL 414 |
| Neosartorya fischeri NRRL 181 | Query 208 GNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | + +|+ ++ + | +| | # | |+ | |||| |||||+||||| Sbjct 743 GMPQQQQQQQQQAVAPMQQQVAVKEEI-#-PPQQPKVRIGLDHFNFLAVLGKGNFGKVM 798 |
| Aspergillus terreus NIH2624 | Query 223 PAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 | + ++ |+ # | + |+ | |||| |||||+||||| Sbjct 747 PVMQQQVAVKEEV#PPPQPKV-RIGLDHFNFLAVLGKGNFGKVM 788 |
| Medicago truncatula | Query 213 RQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKV 264 +|| +|| + |+ +| | + +# | + + | +|| || ++|+| |||| Sbjct 540 KQKRQKAVVTPSNSKKRSSMKSK#HQKFSYTEIVNITD-NFKTIIGEGGFGKV 590 |
| Blumeria graminis | Query 244 RVKLTDFNFLMVLGKGSFGKVM 265 |+ | |||| |||||+||||| Sbjct 826 RIGLDHFNFLAVLGKGNFGKVM 847 |
| Fundulus heteroclitus | Query 230 SPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 265 |||+ # ++ | +||+|| |+||||||||+ Sbjct 78 SPSQQI#NLGPSSNPSAKPSDFHFLKVIGKGSFGKVL 113 |
[Site 2] KAKLGPAGNK227-VISPSEDRKQ
Lys227 Val
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Lys218 | Ala219 | Lys220 | Leu221 | Gly222 | Pro223 | Ala224 | Gly225 | Asn226 | Lys227 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Val228 | Ile229 | Ser230 | Pro231 | Ser232 | Glu233 | Asp234 | Arg235 | Lys236 | Gln237 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| NVPIPEGDEEGNMELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLG |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 124.00 | 12 | - |
| 2 | Homo sapiens | 124.00 | 11 | protein kinase C, alpha variant |
| 3 | Mus musculus | 124.00 | 8 | protein kinase C |
| 4 | synthetic construct | 124.00 | 1 | protein kinase C alpha |
| 5 | Rattus norvegicus | 122.00 | 5 | PREDICTED: similar to Protein kinase C alpha type |
| 6 | Oryctolagus cuniculus | 121.00 | 5 | KPCA_RABIT Protein kinase C alpha type (PKC-alpha) |
| 7 | Canis familiaris | 121.00 | 4 | PREDICTED: similar to Protein kinase C, alpha type |
| 8 | Bos taurus | 121.00 | 4 | protein kinase C, alpha |
| 9 | Monodelphis domestica | 110.00 | 4 | PREDICTED: similar to protein kinase C |
| 10 | Gallus gallus | 107.00 | 3 | protein kinase C, alpha |
| 11 | Xenopus tropicalis | 97.40 | 1 | hypothetical protein LOC780209 |
| 12 | Latimeria chalumnae | 97.10 | 2 | protein kinase C alpha |
| 13 | Xenopus laevis | 90.10 | 1 | protein kinase C, alpha |
| 14 | Protopterus dolloi | 84.70 | 2 | protein kinase C alpha |
| 15 | Takifugu rubripes | 73.90 | 1 | protein kinase C, alpha type |
| 16 | Danio rerio | 69.30 | 7 | protein kinase C, beta 1 |
| 17 | Scyliorhinus canicula | 68.60 | 2 | protein kinase C alpha |
| 18 | Tetraodon nigroviridis | 67.40 | 3 | unnamed protein product |
| 19 | Macaca mulatta | 60.50 | 9 | PREDICTED: protein kinase C, beta 1 isoform 4 |
| 20 | Petromyzon marinus | 57.00 | 1 | protein kinase C |
| 21 | Myxine glutinosa | 45.80 | 1 | protein kinase C |
| 22 | Macaca fascicularis | 38.90 | 1 | KPCG_MACFA Protein kinase C gamma type (PKC-gamma) |
| 23 | Branchiostoma lanceolatum | 38.10 | 1 | protein kinase C |
| 24 | Bombyx mori | 37.00 | 1 | conventional protein kinase C |
| 25 | Apis mellifera | 36.20 | 1 | PREDICTED: similar to Protein C kinase 53E CG6622- |
| 26 | Anopheles gambiae str. PEST | 35.00 | 1 | ENSANGP00000009078 |
| 27 | Aedes aegypti | 34.70 | 1 | protein kinase c |
| 28 | Drosophila melanogaster | 33.90 | 4 | unnamed protein product |
| 29 | Aplysia californica | 33.50 | 1 | KPC1_APLCA Calcium-dependent protein kinase C (APL |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |
| Homo sapiens | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |
| Mus musculus | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |
| synthetic construct | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |
| Rattus norvegicus | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 ||||||||||||+|||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 227 NVPIPEGDEEGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 286 |
| Oryctolagus cuniculus | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |||||||||+||+|||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Canis familiaris | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 ||||||||||||+|||||||||||||||||#||||||||+||||||||||||||||||||| Sbjct 205 NVPIPEGDEEGNVELRQKFEKAKLGPAGNK#VISPSEDRRQPSNNLDRVKLTDFNFLMVLG 264 |
| Bos taurus | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 ||||||||||||+|||||||||||||||||#||||||||+||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNVELRQKFEKAKLGPAGNK#VISPSEDRRQPSNNLDRVKLTDFNFLMVLG 346 |
| Monodelphis domestica | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |||||||||||||||||||||||||| |||#||| |+||| |+|||||||||||||||||| Sbjct 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISSSDDRK-PTNNLDRVKLTDFNFLMVLG 345 |
| Gallus gallus | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 255 |||||+ ||+|| |||||||||||||||||#||+||||| |||||||||||||||||| Sbjct 287 NVPIPDADEDGNAELRQKFEKAKLGPAGNK#VITPSEDRNSSVPSNNLDRVKLTDFNFLMV 346 Query 256 LG 257 || Query 256 LG 257 |
| Xenopus tropicalis | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 255 |||||| +++||+|||||||||||||||||#||||+++|+ ||||+| |+||||+|||| Sbjct 291 NVPIPEEEDDGNIELRQKFEKAKLGPAGNK#VISPTDERRPYVPSNNIDSVRLTDFSFLMV 350 Query 256 LG 257 || Query 256 LG 257 |
| Latimeria chalumnae | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 255 |||| | |+ ||+|||||||||||||||+|#|||| |+|| |||||||||||||||||| Sbjct 209 NVPISEADD-GNVELRQKFEKAKLGPAGSK#VISPVEERKSSTPSNNLDRVKLTDFNFLMV 267 Query 256 LG 257 || Query 256 LG 257 |
| Xenopus laevis | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 255 |||||| |+ ||+|||||||||||||||||#||+|+ +|+ ||||+| ++|||| |||| Sbjct 291 NVPIPEADD-GNLELRQKFEKAKLGPAGNK#VINPTGERRPYIPSNNIDSIRLTDFCFLMV 349 Query 256 LG 257 || Query 256 LG 257 |
| Protopterus dolloi | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |||||+ |+ ||+ ||||||||+||||| |#|||| | ||||| || ||||+|||| Sbjct 207 NVPIPDADD-GNVGLRQKFEKARLGPAGKK#VISPERKSSLPLNNLDRFKLEDFNFVMVLG 265 |
| Takifugu rubripes | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRK--QPSNNLDRVKLTDFNFLMV 255 |||||| |+ |+|||||||||||| | |#||+||+ |+ || |+|||+| ||||| + Sbjct 285 NVPIPEVDDV-NLELRQKFEKAKLGQ-GKK#VITPSDHRRFSLPSGNMDRVRLNDFNFLAL 342 Query 256 LG 257 || Query 256 LG 257 |
| Danio rerio | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSN-NLDRVKLTDFNFLMVL 256 |||+| |||| |||||||+||+||+ # | + | || | ||+||+|||||||| Sbjct 286 NVPVPPEGEEGNEELRQKFERAKIGPSKTD#GSSSNAISKFDSNGNRDRMKLSDFNFLMVL 345 Query 257 G 257 | Query 257 G 257 |
| Scyliorhinus canicula | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |||| | ||+ |||+||||||||||| |# | + |+|+|| | | ||||||||| Sbjct 220 NVPIIEDDEDS--ELRKKFEKAKLGPAGKK#AI--EKKPSSPTNDLDHVHLEDFNFLMVLG 275 |
| Tetraodon nigroviridis | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK--#VISPSEDRKQPSNNLDRVKLTDFNFLMV 255 |||+| |||| |||||||+||+|| | # + + | + | ||+|| ||||||| Sbjct 223 NVPVPPEGEEGNEELRQKFERAKIGPGKNTDG#KSANAASRFDSNGNQDRMKLADFNFLMV 282 Query 256 LG 257 || Query 256 LG 257 |
| Macaca mulatta | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#V----ISPSEDRKQPSNNLDRVKLTDFNFL 253 |||+| ||| |||||||+||+ | |#| + + + + | ||+|||||||| Sbjct 158 NVPVPPEGSEGNEELRQKFERAKIS-QGTK#VPEEKTTNTVSKFDNNGNRDRMKLTDFNFL 216 Query 254 MVLG 257 |||| Query 254 MVLG 257 |
| Petromyzon marinus | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISP--SEDRKQPS-------NNLDRVKLT 248 |||| |+|+ |+|+|||||+|||+ # + | |++|+ | |+|||| Sbjct 217 NVPIAPDIEDGDTEMRRKFEKARLGPS---#-VKPRASDERRANSLSAILNNANVDRVKAD 272 Query 249 DFNFLMVLG 257 ||||||||| Query 249 DFNFLMVLG 257 |
| Myxine glutinosa | Query 198 NVPI-PEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPS---NNLDRVKLTDFNFL 253 |||+ |||+| +||||+ +++++ + # ||++|+ | + |||| | || || Sbjct 208 NVPVAPEGEE--GLELRQRLQRSQIARSDKN#KQSPAKDQPSDSASLSGLDRVNLEDFVFL 265 Query 254 MVLG 257 ||| Sbjct 266 TVLG 269 |
| Macaca fascicularis | Query 198 NVPIPEGDEEGNMELRQKFE----------KAKLGPAGNK#VISPSEDRKQPSN-----NL 242 |||+ + | | | |||| + ++||+ + #+ ||| | + Sbjct 287 NVPVADAD---NCSLLQKFEACNYPLELYERVRMGPSSSP#IPSPSPSPTDPKRCFFGASP 343 Query 243 DRVKLTDFNFLMVLG 257 |+ ++||+|||||| Sbjct 344 GRLHISDFSFLMVLG 358 |
| Branchiostoma lanceolatum | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |||| + +|| +|++ +| || +# ||+ | || +| ||||||||| Sbjct 218 NVPIAD-EEENVAKLKEHLQKQKLDEQRKQ#KSKRSEECNIGS--LDHMKAADFNFLMVLG 274 |
| Bombyx mori | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLMV 255 |||+|| || +| | + + | +# | ||+ | | | ++ |||||+|| Sbjct 290 NVPVPE---EG-ADLVQLKNQMRATTVGAR#RPPPPPDREVPHNVAAADVIRATDFNFIMV 345 Query 256 LG 257 || Query 256 LG 257 |
| Apis mellifera | Query 198 NVPIPE-GDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLM 254 |||+|| | + ++++ +| + |# + ++|++ | | | ++ +|||||| Sbjct 304 NVPVPEEGVDLAELKMKPSPQKTSV----TK#KTTTTQDKEVPHNMGKSDLIRASDFNFLM 359 Query 255 VLG 257 ||| Query 255 VLG 257 |
| Anopheles gambiae str. PEST | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLMV 255 |||+|| + ++|+ + | + |# | |+ | | | ++ |||||||| Sbjct 227 NVPVPEEGAD-LVQLKSQMRKTSI----TK#KIPMMGDKDVPHNMTKKDVIRATDFNFLMV 281 Query 256 LG 257 || Query 256 LG 257 |
| Aedes aegypti | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 |||+|| || ++ | + | + # + +| | ++ |||||||||| Sbjct 235 NVPVPE---EGTDLVQLKSQMRKTSISKKA#PVLCDKDVPHNMGKKDVIRATDFNFLMVLG 291 |
| Drosophila melanogaster | Query 198 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 ||| + ||+ ++|+|| + | #++ |+ |+ | ++ |||||+ ||| Sbjct 296 NVPCAD-DEQDLLKLKQKPSQKK------P#MVMRSDTNTHTSSKKDMIRATDFNFIKVLG 348 |
| Aplysia californica | Query 199 VPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 257 ||+ + | |++ | ++ + ++# | |+ | + | |+ +||||| ||| Sbjct 272 VPVTDDITESIQEIKSKMHRSSIS---SE#KRYPEPDKVQNMSKQDIVRASDFNFLTVLG 327 |
[Site 3] ELRQKFEKAK220-LGPAGNKVIS
Lys220 Leu
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu211 | Leu212 | Arg213 | Gln214 | Lys215 | Phe216 | Glu217 | Lys218 | Ala219 | Lys220 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Leu221 | Gly222 | Pro223 | Ala224 | Gly225 | Asn226 | Lys227 | Val228 | Ile229 | Ser230 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| QEEGEYYNVPIPEGDEEGNMELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDF |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 126.00 | 13 | - |
| 2 | Homo sapiens | 126.00 | 11 | protein kinase C, alpha variant |
| 3 | Mus musculus | 126.00 | 9 | protein kinase C |
| 4 | synthetic construct | 126.00 | 1 | protein kinase C alpha |
| 5 | Rattus norvegicus | 124.00 | 5 | PREDICTED: similar to Protein kinase C alpha type |
| 6 | Oryctolagus cuniculus | 123.00 | 5 | KPCA_RABIT Protein kinase C alpha type (PKC-alpha) |
| 7 | Canis familiaris | 123.00 | 4 | PREDICTED: similar to Protein kinase C, alpha type |
| 8 | Bos taurus | 123.00 | 4 | protein kinase C, alpha |
| 9 | Monodelphis domestica | 112.00 | 4 | PREDICTED: similar to protein kinase C |
| 10 | Gallus gallus | 109.00 | 3 | protein kinase C, alpha |
| 11 | Xenopus tropicalis | 101.00 | 1 | hypothetical protein LOC780209 |
| 12 | Latimeria chalumnae | 99.00 | 2 | protein kinase C alpha |
| 13 | Xenopus laevis | 95.50 | 1 | protein kinase C, alpha |
| 14 | Protopterus dolloi | 87.80 | 2 | protein kinase C alpha |
| 15 | Takifugu rubripes | 79.30 | 1 | protein kinase C, alpha type |
| 16 | Scyliorhinus canicula | 70.50 | 2 | protein kinase C alpha |
| 17 | Danio rerio | 69.70 | 7 | protein kinase C, beta 1 |
| 18 | Tetraodon nigroviridis | 67.80 | 3 | unnamed protein product |
| 19 | Macaca mulatta | 60.80 | 9 | PREDICTED: protein kinase C, beta 1 isoform 4 |
| 20 | Petromyzon marinus | 58.90 | 1 | protein kinase C |
| 21 | Myxine glutinosa | 53.50 | 1 | protein kinase C |
| 22 | Macaca fascicularis | 42.70 | 1 | KPCG_MACFA Protein kinase C gamma type (PKC-gamma) |
| 23 | Branchiostoma lanceolatum | 40.00 | 1 | protein kinase C |
| 24 | Apis mellifera | 38.10 | 1 | PREDICTED: similar to Protein C kinase 53E CG6622- |
| 25 | Bombyx mori | 38.10 | 1 | conventional protein kinase C |
| 26 | Drosophila melanogaster | 37.70 | 4 | unnamed protein product |
| 27 | Anopheles gambiae str. PEST | 37.00 | 1 | ENSANGP00000009078 |
| 28 | Aedes aegypti | 36.60 | 1 | protein kinase c |
| 29 | Aplysia californica | 36.20 | 1 | KPC1_APLCA Calcium-dependent protein kinase C (APL |
| 30 | Drosophila pseudoobscura | 33.90 | 1 | GA19732-PA |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 |
| Homo sapiens | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 |
| Mus musculus | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 |
| synthetic construct | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 |
| Rattus norvegicus | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 |||||||||||||||||||+||||||||||#|||||||||||||||||||||||||||||| Sbjct 220 QEEGEYYNVPIPEGDEEGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 279 |
| Oryctolagus cuniculus | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||||||||+||+||||||||||#|||||||||||||||||||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Canis familiaris | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 |||||||||||||||||||+||||||||||#|||||||||||||||+|||||||||||||| Sbjct 198 QEEGEYYNVPIPEGDEEGNVELRQKFEKAK#LGPAGNKVISPSEDRRQPSNNLDRVKLTDF 257 |
| Bos taurus | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 |||||||||||||||||||+||||||||||#|||||||||||||||+|||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNVELRQKFEKAK#LGPAGNKVISPSEDRRQPSNNLDRVKLTDF 339 |
| Monodelphis domestica | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||||||||||||||||||||||#||| |||||| |+||| |+||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISSSDDRK-PTNNLDRVKLTDF 338 |
| Gallus gallus | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQ--PSNNLDRVKLT 248 ||||||||||||+ ||+|| ||||||||||#|||||||||+||||| ||||||||||| Sbjct 280 QEEGEYYNVPIPDADEDGNAELRQKFEKAK#LGPAGNKVITPSEDRNSSVPSNNLDRVKLT 339 Query 249 DF 250 || Query 249 DF 250 |
| Xenopus tropicalis | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQ--PSNNLDRVKLT 248 ||||||||||||| +++||+||||||||||#|||||||||||+++|+ ||||+| |+|| Sbjct 284 QEEGEYYNVPIPEEEDDGNIELRQKFEKAK#LGPAGNKVISPTDERRPYVPSNNIDSVRLT 343 Query 249 DF 250 || Query 249 DF 250 |
| Latimeria chalumnae | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQ--PSNNLDRVKLT 248 ||||||||||| | |+ ||+||||||||||#|||||+||||| |+|| ||||||||||| Sbjct 202 QEEGEYYNVPISEADD-GNVELRQKFEKAK#LGPAGSKVISPVEERKSSTPSNNLDRVKLT 260 Query 249 DF 250 || Query 249 DF 250 |
| Xenopus laevis | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQ--PSNNLDRVKLT 248 ||||||||||||| |+ ||+||||||||||#|||||||||+|+ +|+ ||||+| ++|| Sbjct 284 QEEGEYYNVPIPEADD-GNLELRQKFEKAK#LGPAGNKVINPTGERRPYIPSNNIDSIRLT 342 Query 249 DF 250 || Query 249 DF 250 |
| Protopterus dolloi | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||||+ |+ ||+ ||||||||+#||||| ||||| | ||||| || || Sbjct 200 QEEGEYYNVPIPDADD-GNVGLRQKFEKAR#LGPAGKKVISPERKSSLPLNNLDRFKLEDF 258 |
| Takifugu rubripes | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRK--QPSNNLDRVKLT 248 ||||||||||||| |+ |+||||||||||#|| | |||+||+ |+ || |+|||+| Sbjct 278 QEEGEYYNVPIPEVDDV-NLELRQKFEKAK#LG-QGKKVITPSDHRRFSLPSGNMDRVRLN 335 Query 249 DF 250 || Query 249 DF 250 |
| Scyliorhinus canicula | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||| | ||+ |||+||||||#||||| | | + |+|+|| | | || Sbjct 213 QEEGEYYNVPIIEDDEDS--ELRKKFEKAK#LGPAGKKAI--EKKPSSPTNDLDHVHLEDF 268 |
| Danio rerio | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSN-NLDRVKLTD 249 ||||||+|||+| |||| |||||||+||#+||+ | + | || | ||+||+| Sbjct 279 QEEGEYFNVPVPPEGEEGNEELRQKFERAK#IGPSKTDGSSSNAISKFDSNGNRDRMKLSD 338 Query 250 F 250 | Query 250 F 250 |
| Tetraodon nigroviridis | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNK--VISPSEDRKQPSNNLDRVKLT 248 ||||||+|||+| |||| |||||||+||#+|| | + + | + | ||+|| Sbjct 216 QEEGEYFNVPVPPEGEEGNEELRQKFERAK#IGPGKNTDGKSANAASRFDSNGNQDRMKLA 275 Query 249 DF 250 || Query 249 DF 250 |
| Macaca mulatta | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKV----ISPSEDRKQPSNNLDRVK 246 ||||||+|||+| ||| |||||||+||#+ | || + + + + | ||+| Sbjct 151 QEEGEYFNVPVPPEGSEGNEELRQKFERAK#IS-QGTKVPEEKTTNTVSKFDNNGNRDRMK 209 Query 247 LTDF 250 |||| Query 247 LTDF 250 |
| Petromyzon marinus | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISP--SEDRKQPS-------NN 241 ||||||||||| |+|+ |+|+|||||+#|||+ + | |++|+ | | Sbjct 210 QEEGEYYNVPIAPDIEDGDTEMRRKFEKAR#LGPS----VKPRASDERRANSLSAILNNAN 265 Query 242 LDRVKLTDF 250 +|||| || Sbjct 266 VDRVKADDF 274 |
| Myxine glutinosa | Query 191 QEEGEYYNVPI-PEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPS---NNLDRVK 246 ||||||||||+ |||+| +||||+ ++++#+ + ||++|+ | + |||| Sbjct 201 QEEGEYYNVPVAPEGEE--GLELRQRLQRSQ#IARSDKNKQSPAKDQPSDSASLSGLDRVN 258 Query 247 LTDF 250 | || Sbjct 259 LEDF 262 |
| Macaca fascicularis | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKF----------EKAK#LGPAGNKVISPSEDRKQPSN 240 ||||||||||+ + | | | ||| |+ +#+||+ + + ||| | Sbjct 280 QEEGEYYNVPVADAD---NCSLLQKFEACNYPLELYERVR#MGPSSSPIPSPSPSPTDPKR 336 Query 241 -----NLDRVKLTDF 250 + |+ ++|| Sbjct 337 CFFGASPGRLHISDF 351 |
| Branchiostoma lanceolatum | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||| + +|| +|++ +| |#| + ||+ +|| +| || Sbjct 211 QEEGEYYNVPIAD-EEENVAKLKEHLQKQK#LDEQRKQKSKRSEECN--IGSLDHMKAADF 267 |
| Apis mellifera | Query 191 QEEGEYYNVPIP-EGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSN--NLDRVKL 247 ||||||||||+| || + ++++ +| #+ | + ++|++ | | | ++ Sbjct 297 QEEGEYYNVPVPEEGVDLAELKMKPSPQKTS#V----TKKTTTTQDKEVPHNMGKSDLIRA 352 Query 248 TDF 250 +|| Sbjct 353 SDF 355 |
| Bombyx mori | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSN--NLDRVKLT 248 |||||+||||+| ||| +| | + +# | + | ||+ | | | ++ | Sbjct 283 QEEGEFYNVPVP---EEG-ADLVQLKNQMR#ATTVGARRPPPPPDREVPHNVAAADVIRAT 338 Query 249 DF 250 || Query 249 DF 250 |
| Drosophila melanogaster | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 |+|||||||| + ||+ ++|+|| + |# ++ |+ |+ | ++ ||| Sbjct 289 QDEGEYYNVPCAD-DEQDLLKLKQKPSQKK#------PMVMRSDTNTHTSSKKDMIRATDF 341 |
| Anopheles gambiae str. PEST | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSN--NLDRVKLT 248 ||||||||||+|| + ++|+ + | #+ | | |+ | | | ++ | Sbjct 220 QEEGEYYNVPVPE-EGADLVQLKSQMRKTS#I----TKKIPMMGDKDVPHNMTKKDVIRAT 274 Query 249 DF 250 || Query 249 DF 250 |
| Aedes aegypti | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 ||||||||||+| ||| ++ | + |# + + +| | ++ ||| Sbjct 228 QEEGEYYNVPVP---EEGTDLVQLKSQMRK#TSISKKAPVLCDKDVPHNMGKKDVIRATDF 284 |
| Aplysia californica | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 250 |||||+| ||+ + | |++ | ++ #+ ++ | |+ | + | |+ +|| Sbjct 264 QEEGEFYGVPVTDDITESIQEIKSKMHRSS#I---SSEKRYPEPDKVQNMSKQDIVRASDF 320 |
| Drosophila pseudoobscura | Query 191 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPS--NNLDRVKLT 248 |+|||||||| + ||+ ++|+|| # |+ | + | | + | ++ | Sbjct 175 QDEGEYYNVPCAD-DEQDLLKLKQK-----#--PSQKKPLVMRSDTNTHSSISKKDMIRAT 226 Query 249 DF 250 || Query 249 DF 250 |
* References
None.