XSB0715 : PREDICTED: similar to Autophagy protein 5-like (APG5-like) (Apoptosis-specific protein) isoform 2 [Canis familiaris]
[ CaMP Format ]
This entry is computationally expanded from SB0014
* Basic Information
| Organism | Canis lupus familiaris (dog) |
| Protein Names | similar to Autophagy protein 5-like (APG5-like) (Apoptosis-specific protein) isoform 2 |
| Gene Names | LOC610868; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 1 mRNA, 72 ESTs, 11 Proteins |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 307 aa
Average Mass: 36.227 kDa
Monoisotopic Mass: 36.203 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| BTK 1. | 37 | 67 | -10.1 | 7.9 |
| APG5 1. | 111 | 304 | 368.7 | 1.1e-107 |
| --- cleavage 225 (inside APG5 111..304) --- | ||||
3. Sequence Information
Fasta Sequence: XSB0715.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] YIPFRIYQTT225-TERPFIQKLF
Thr225 
Thr
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Tyr216 | Ile217 | Pro218 | Phe219 | Arg220 | Ile221 | Tyr222 | Gln223 | Thr224 | Thr225 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr226 | Glu227 | Arg228 | Pro229 | Phe230 | Ile231 | Gln232 | Lys233 | Leu234 | Phe235 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| QFWAINRKLMEYPAEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLKEVC |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Canis familiaris | 129.00 | 3 | PREDICTED: similar to Autophagy protein 5-like (AP |
| 2 | Macaca mulatta | 129.00 | 2 | PREDICTED: ATG5 autophagy related 5 homolog (S. ce |
| 3 | Homo sapiens | 129.00 | 2 | APG5 autophagy 5-like |
| 4 | Pan troglodytes | 129.00 | 1 | PREDICTED: hypothetical protein LOC462905 isoform |
| 5 | Pongo pygmaeus | 129.00 | 1 | ATG5_PONPY Autophagy protein 5 (APG5-like) emb |
| 6 | Bos taurus | 126.00 | 2 | hypothetical protein LOC532686 |
| 7 | Mus musculus | 125.00 | 2 | autophagy-related 5-like |
| 8 | Monodelphis domestica | 124.00 | 1 | PREDICTED: similar to Autophagy protein 5 |
| 9 | Rattus norvegicus | 124.00 | 1 | ATG5_RAT Autophagy protein 5 emb |
| 10 | Sus scrofa | 122.00 | 1 | APG5 autophagy 5-like |
| 11 | Gallus gallus | 116.00 | 1 | APG5 autophagy 5-like |
| 12 | Ictalurus punctatus | 108.00 | 1 | autophagy protein 5 |
| 13 | Gasterosteus aculeatus | 107.00 | 1 | autophagy protein 5 |
| 14 | Oryzias latipes | 106.00 | 1 | autophagy protein 5 |
| 15 | Xenopus laevis | 104.00 | 2 | autophagy protein 5 |
| 16 | Pimephales promelas | 104.00 | 1 | autophagy protein 5 |
| 17 | Tetraodon nigroviridis | 103.00 | 2 | autophagy protein 5 |
| 18 | Xenopus tropicalis | 103.00 | 1 | APG5 autophagy 5-like |
| 19 | Danio rerio | 102.00 | 2 | APG5 autophagy 5-like protein isoform 2 |
| 20 | Apis mellifera | 65.90 | 1 | PREDICTED: similar to APG5 autophagy 5-like protei |
| 21 | Tribolium castaneum | 59.70 | 1 | PREDICTED: similar to CG1643-PA |
| 22 | Callinectes sapidus | 58.20 | 1 | autophagy protein 5 |
| 23 | Drosophila yakuba | 55.80 | 1 | autophagy protein 5 |
| 24 | Drosophila erecta | 54.70 | 1 | autophagy protein 5 |
| 25 | Drosophila ananassae | 53.50 | 1 | autophagy protein 5 |
| 26 | Drosophila simulans | 53.10 | 1 | autophagy protein 5 |
| 27 | Drosophila melanogaster | 53.10 | 1 | Autophagy-specific gene 5 CG1643-PA |
| 28 | Aedes aegypti | 52.40 | 1 | Autophagy-specific protein, putative |
| 29 | Drosophila persimilis | 52.00 | 1 | autophagy protein 5 |
| 30 | Drosophila pseudoobscura | 52.00 | 1 | GA14069-PA |
| 31 | Anopheles gambiae str. PEST | 51.60 | 1 | ENSANGP00000012467 |
| 32 | Drosophila grimshawi | 51.20 | 1 | autophagy protein 5 |
| 33 | Strongylocentrotus purpuratus | 50.40 | 1 | PREDICTED: similar to autophagy protein 5, partial |
| 34 | Drosophila virilis | 48.90 | 1 | autophagy protein 5 |
| 35 | Drosophila mojavensis | 48.10 | 1 | autophagy protein 5 |
| 36 | Caenorhabditis elegans | 41.20 | 1 | ATG (AuTophaGy) Related family member (atgr-5) |
| 37 | Caenorhabditis briggsae | 41.20 | 1 | Hypothetical protein CBG22152 |
| 38 | Schistosoma japonicum | 38.90 | 1 | SJCHGC03143 protein |
| 39 | Ciona intestinalis | 36.60 | 1 | autophagy protein 5 |
Top-ranked sequences
| organism | matching |
|---|---|
| Canis familiaris | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 |
| Macaca mulatta | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 |
| Homo sapiens | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 |
| Pan troglodytes | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 |
| Pongo pygmaeus | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 |
| Bos taurus | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||||||||||||||||||||||#|||||||||||||+ ||||||||||||||| Sbjct 164 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVSTDGQLHTLGDLLKEVC 223 |
| Mus musculus | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||||| ||||||||||||||||#||||||||||||||||||||||||||+||| Sbjct 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 |
| Monodelphis domestica | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 |||||||||||||||+|||||||||||| |#|||||||||||||| ||||||||||||||| Sbjct 164 QFWAINRKLMEYPAEDNGFRYIPFRIYQAT#TERPFIQKLFRPVATDGQLHTLGDLLKEVC 223 |
| Rattus norvegicus | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||| ||||||||| ||||||||||||||||#||||||||||||||||||||||||||+||| Sbjct 164 QFWTINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 |
| Sus scrofa | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||| |||||+||| ||||||||||||||||#||||||||||||||||||||||||||+||| Sbjct 164 QFWTINRKLIEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 |
| Gallus gallus | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||||| |++||||||||||| |#||||||||||||+|+ |||||||||||+|| Sbjct 164 QFWAINRKLMEYPPEDSGFRYIPFRIYQAT#TERPFIQKLFRPIASGGQLHTLGDLLKDVC 223 |
| Ictalurus punctatus | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||||| || |||||||||||| #++|||||| ||||+++| |||||||||+| Sbjct 164 QFWAINRKLMEYPTEEGGFRYIPFRIYQTL#SDRPFIQKPFRPVSSEGHAHTLGDLLKEMC 223 |
| Gasterosteus aculeatus | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 |||||||||||| +|+ |||||||||||||#++|||||||||| + +| |||||||||+| Sbjct 164 QFWAINRKLMEYSSEDGGFRYIPFRIYQTT#SDRPFIQKLFRPTSPEGSAHTLGDLLKEMC 223 |
| Oryzias latipes | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||+|||||||| || |||||||||||||# +|||||+|||||+ +| ||| |||||+| Sbjct 164 QFWAMNRKLMEYPTEEGGFRYIPFRIYQTT#NDRPFIQRLFRPVSTEGNPHTLFDLLKEMC 223 |
| Xenopus laevis | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 |||||||||||+ |+ |||||||||||| # +|||||||||||| ||+ ||||||++|+| Sbjct 195 QFWAINRKLMEFSPEDGGFRYIPFRIYQTI#NDRPFIQKLFRPVANDGRPHTLGDLIREIC 254 |
| Pimephales promelas | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+|||||||| |+ |||||||||||||#++|||||||||||+|+| ||||||||+ Sbjct 164 QFWAMNRKLMEYPTEDGGFRYIPFRIYQTT#SDRPFIQKLFRPVSAEGHALTLGDLLKEL 222 |
| Tetraodon nigroviridis | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||+||||||| || |||||||||||||# +|||||+|||||+ +| ||| |||||+| Sbjct 164 QFWAMNRKLMEYSTEEGGFRYIPFRIYQTT#NDRPFIQRLFRPVSTEGNPHTLFDLLKEMC 223 |
| Xenopus tropicalis | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 255 ||||||||||| | |+ ||||||||||| # ||||||||||||| ||+ +|||||++||| Sbjct 164 QFWAINRKLMEVPPEDGGFRYIPFRIYQAI#NERPFIQKLFRPVANDGRPYTLGDLIREVC 223 |
| Danio rerio | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+|||||||| || |||||||||||| #++||||| |||||+++|| ||||||||+ Sbjct 166 QFWAMNRKLMEYPTEEGGFRYIPFRIYQTM#SDRPFIQTLFRPVSSEGQALTLGDLLKEL 224 |
| Apis mellifera | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 |||++|||||| | ||+||||| | |#+| ++||| +|| +|| || || || Sbjct 167 QFWSVNRKLMEASNIEEGFKYIPFRCY--T#SEDKYVQKLVKPVNEEGQRKTLRHLLNEV 223 |
| Tribolium castaneum | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+|||||| |+ |+||||+ | # + + ||| +|| ||+ || ||+ |+ Sbjct 167 QFWAVNRKLMEVSQEQEHFKYIPFKCY---#LDDGYRQKLIKPVDEDGRRKTLQDLINEM 222 |
| Callinectes sapidus | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKE 253 ||||||||||| || ||++||||++ # + | ||+| ||+ ||+ || ||| | Sbjct 166 QFWAINRKLMESTPEE-GFKFIPFRLH-CP#FQAP-IQRLIRPLTEDGRRVTLADLLME 220 |
| Drosophila yakuba | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+||+||| |++ |+ || ||| | # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYADQESFKNIPLRIY-TD#DDFTYSQKLISPISEGGQKKSLADLMAEL 223 |
| Drosophila erecta | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+||+||| ++ |+ || ||| | # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDQESFKNIPLRIY-TD#DDFTYTQKLISPISEGGQKKSLADLMAEL 223 |
| Drosophila ananassae | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+||+||| ++ |++|| |+| # + + ||| |+ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDQESFKHIPLRLY-AD#DDFTYTQKLISPITESGQKKSLADLMAEL 223 |
| Drosophila simulans | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+||+||| + |+ || ||| | # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDLESFKNIPLRIY-TD#DDFTYTQKLISPISVGGQKKSLADLMAEL 223 |
| Drosophila melanogaster | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+||+||| + |+ || ||| | # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDLESFKNIPLRIY-TD#DDFTYTQKLISPISVGGQKKSLADLMAEL 223 |
| Aedes aegypti | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKE 253 ||||+||+||| +++||++|| | | # + + ||| | || || |||++ Sbjct 165 QFWAVNRRLMEPIPDQDGFKHIPVRCY--A#EDGSYQQKLVAPSTETGQKRTLQDLLED 220 |
| Drosophila persimilis | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+||+||| ++ |+ || |+| # + + ||| |++ || +| ||+ |+ Sbjct 165 QFWAVNRRLMEPYGDQESFKNIPVRLY-ND#DDFTYTQKLISPISESGQKKSLADLMAEL 222 |
| Drosophila pseudoobscura | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+||+||| ++ |+ || |+| # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDQESFKNIPVRLY-ND#DDFTYTQKLISPISESGQKKSLADLMAEL 223 |
| Anopheles gambiae str. PEST | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKE 253 ||||+||+||| +++||++|| | | # + + ||| | | || | ||| + Sbjct 165 QFWAVNRRLMEPIPDQDGFKHIPVRCY--A#EDGTYQQKLVAPSTASGQKRLLQDLLDD 220 |
| Drosophila grimshawi | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+||+||| +++ |+ || | | # + ++||| |++ || | ||+ |+ Sbjct 164 QFWAVNRRLMEPYSDQESFKNIPIRFYY-D#DDFTYMQKLITPLSQSGQKKNLADLMAEL 221 |
| Strongylocentrotus purpuratus | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKE 253 ||| ||+||| + |++|||+|+| # |+ |+||+|| +|+ || |||| Sbjct 139 QFWTTNRRLMER-LNNDPFKFIPFKIFQVP#-EKLHTQRLFKPVNDEGEPRTLRALLKE 194 |
| Drosophila virilis | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ||||+||+||| +++ |+ || | | # + ++||| |+ || | ||+ |+ Sbjct 166 QFWAVNRRLMEPYSDQESFKNIPVRFYY-D#DDFTYMQKLITPLNESGQKKNLADLMIEL 223 |
| Drosophila mojavensis | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 |||||||+||| ++ |+ || | | # + ++||| |+ || | ||+ |+ Sbjct 166 QFWAINRRLMEPYNDQESFKNIPVRFYY-D#DDFTYMQKLISPLNEAGQKKNLADLMAEL 223 |
| Caenorhabditis elegans | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 +|| | +|||| +| | | +|| |+| # + | | | || | |+|+ + +| Sbjct 163 EFWTIVQKLME-TSEGNEFAHIPLRVY--V#KNQAFKQALITAKHPDGSLRTIGEAVSDV 218 |
| Caenorhabditis briggsae | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEV 254 ++| + +|||+ | + | ++| |+| # +|| | | || | |+|| + |+ Sbjct 165 EYWGMIQKLMD-PKDGKDFLHVPLRVY--V#KNQPFKQALITVKHPDGSLRTIGDAVSEI 220 |
| Schistosoma japonicum | Query 196 QFWAINRKLME--------YPAEE------------------------NGFRYIPFRIYQ 223 |||+|| |||| |+|| ||||| |+| Sbjct 66 QFWSINSKLMEPLPYNTKDLPSEEIPISEIPENKSKSANLDNISSSRCKTFRYIPCRLY- 124 Query 224 TT#TERP------FIQKLFRPVAADGQLHTLGDLLK 252 #+| | | ||| ||+ || | +| | ++ Sbjct 125 CV#SENPNSAPSGFTQKLIRPLNDDGSLISLQDAIR 159 |
| Ciona intestinalis | Query 196 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRP 237 +||+||++ | + ||+|| |+| # + |||||+| Sbjct 164 EFWSINKQFMSGFETTDYFRFIPLRVY---#FQNRIIQKLFKP 202 |
* References
None.