XSB0800 : unnamed protein product [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0081
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | Putative uncharacterized protein |
| Gene Names | Tln1 |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 2541 aa
Average Mass: 269.837 kDa
Monoisotopic Mass: 269.669 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| FERM_N 1. | 90 | 199 | 101.2 | 3.5e-27 |
| FERM_M 1. | 201 | 313 | 144.7 | 2.8e-40 |
| --- cleavage 433 --- | ||||
| Talin_middle 1. | 491 | 652 | 372.5 | 7.7e-109 |
| Stork_head 1. | 728 | 795 | -14.0 | 3.2 |
| Inhibitor_I34 1. | 840 | 905 | -11.3 | 7.9 |
| CRA_rpt 1. | 907 | 945 | -6.0 | 8.2 |
| CMD 1. | 977 | 1059 | -15.1 | 8.7 |
| DUF1707 1. | 1160 | 1204 | -25.0 | 4.3 |
| XhlA 1. | 1360 | 1411 | -17.3 | 6.8 |
| Mucin 1. | 1476 | 1614 | -38.2 | 9 |
| WSK 1. | 1635 | 1664 | 0.9 | 8 |
| HHH 1. | 1805 | 1834 | 0.1 | 6.9 |
| VBS 1. | 1849 | 1973 | 288.8 | 1.2e-83 |
| Vir_act_alpha_C 1. | 2184 | 2262 | -17.0 | 0.85 |
| I_LWEQ 1. | 2341 | 2533 | 372.5 | 7.7e-109 |
3. Sequence Information
Fasta Sequence: XSB0800.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] VSPKKSTVLQ433-QQYNRVGKVE
Gln433 
Gln
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Val424 | Ser425 | Pro426 | Lys427 | Lys428 | Ser429 | Thr430 | Val431 | Leu432 | Gln433 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Gln434 | Gln435 | Tyr436 | Asn437 | Arg438 | Val439 | Gly440 | Lys441 | Val442 | Glu443 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| KSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEHGSVALPAIMRSGASGPENF |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 122.00 | 20 | unnamed protein product |
| 2 | Canis familiaris | 122.00 | 16 | PREDICTED: similar to talin 1 isoform 9 |
| 3 | Homo sapiens | 122.00 | 12 | Talin 1 |
| 4 | Macaca mulatta | 122.00 | 3 | PREDICTED: talin 1 |
| 5 | N/A | 122.00 | 2 | 1 |
| 6 | Bos taurus | 122.00 | 2 | PREDICTED: similar to KIAA1027 protein |
| 7 | Rattus norvegicus | 120.00 | 5 | PREDICTED: similar to Talin-1 |
| 8 | Gallus gallus | 112.00 | 1 | talin 1 |
| 9 | Tetraodon nigroviridis | 110.00 | 3 | unnamed protein product |
| 10 | Monodelphis domestica | 108.00 | 1 | PREDICTED: similar to pleckstrin and Sec7 domain c |
| 11 | Danio rerio | 107.00 | 4 | talin 1 |
| 12 | Pan troglodytes | 107.00 | 2 | PREDICTED: talin 2 isoform 2 |
| 13 | Apis mellifera | 72.80 | 2 | PREDICTED: similar to rhea CG6831-PA, partial |
| 14 | Tribolium castaneum | 72.80 | 1 | PREDICTED: similar to CG6831-PA |
| 15 | Anopheles gambiae str. PEST | 66.20 | 1 | ENSANGP00000019107 |
| 16 | Drosophila pseudoobscura | 62.00 | 1 | GA19890-PA |
| 17 | Drosophila melanogaster | 60.80 | 1 | rhea CG6831-PA |
| 18 | Aedes aegypti | 60.10 | 1 | talin |
| 19 | Strongylocentrotus purpuratus | 58.20 | 1 | PREDICTED: similar to talin |
| 20 | Caenorhabditis elegans | 47.40 | 2 | Y71G12B.11a |
| 21 | Caenorhabditis briggsae | 47.40 | 1 | Hypothetical protein CBG22153 |
| 22 | Podocoryne carnea | 35.00 | 1 | AF308653_1 talin |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 |
| Canis familiaris | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 |
| Homo sapiens | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 |
| Macaca mulatta | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 |
| N/A | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 |
| Bos taurus | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 |
| Rattus norvegicus | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ||||||||||||||||||||||||||||||#|||||||| ||||||||||||||||||||| Sbjct 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKAEHGSVALPAIMRSGASGPENF 463 |
| Gallus gallus | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ||||||||||||||||||||||||||||||#||+||||| | ||||||||||+|| ||||| Sbjct 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQFNRVGKAELGSVALPAIMRTGAGGPENF 463 |
| Tetraodon nigroviridis | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ||||||||||||||||||||||||||||+|#|| |+||||| |||||||||||||+|||+| Sbjct 518 KSKDHFGLEGDEESTMLEDSVSPKKSTVMQ#QQCNKVGKVETGSVALPAIMRSGAAGPESF 577 |
| Monodelphis domestica | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 +||| |||||||||||||+||||||||+||#||+|| ||||||||||||+||||+|||| | Sbjct 407 QSKDRFGLEGDEESTMLEESVSPKKSTILQ#QQFNRTGKVEHGSVALPAVMRSGSSGPETF 466 |
| Danio rerio | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPEN 462 ||||||||||||||||||||||||||||||#||+|++|||| ||||||||+|||| |||+ Sbjct 400 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQFNKMGKVETGSVALPAIIRSGAGGPES 458 |
| Pan troglodytes | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 +||| |||||||||||||+||||||||+||#||+|| || |||||||||+||||+|||| | Sbjct 407 QSKDRFGLEGDEESTMLEESVSPKKSTILQ#QQFNRTGKAEHGSVALPAVMRSGSSGPETF 466 |
| Apis mellifera | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGK--VEHGSVALPAIMRSGASG 459 |+|||||+|||| |||+|||||| |+|++|# + + || || |||+||+||+| | Sbjct 271 KAKDHFGIEGDEGSTMVEDSVSPLKATIMQ#HETSNAGKGNVEAVSVAIPAVMRTGVDG 328 |
| Tribolium castaneum | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 ++|||+|+|||| ||| |+||+| |+|+||# + ++|||+ |+| ||+||+| | + | Sbjct 411 QAKDHYGIEGDEGSTMFEESVAPHKATILQ#HELSKVGKLNTESLAKPAVMRAGTDGEKTF 470 |
| Anopheles gambiae str. PEST | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ-#QQYNRVGKVEHGSVALPAIMRSGASGPEN 462 ++|||||+|||| |||+|+||+| |+| || #++ |+ |||| |+| ||||| | | + Sbjct 415 QAKDHFGIEGDEGSTMVEESVAPSKATFLQH#EETNKGGKVETHSIAKPAIMR-GTDGERS 473 Query 463 F 463 + Sbjct 474 Y 474 |
| Drosophila pseudoobscura | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMR 454 ++|||||+|||| |||+|+||+| |+| ||# + ||| ++ |+| | ||| Sbjct 413 QTKDHFGIEGDEGSTMVEESVAPSKATFLQ#HETNRVEQLNVESLAHPGIMR 463 |
| Drosophila melanogaster | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMR 454 ++|||||+|||| |||+|+||+| |+| ||# + ||+ ++ |+| | ||| Sbjct 413 QTKDHFGIEGDEGSTMVEESVAPSKATFLQ#HETNRMEQLNVESLAHPGIMR 463 |
| Aedes aegypti | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ-#QQYNRVGKVEHGSVALPAIMR 454 ++|+|||+|||| |||+|+||+| |+| || #++ |||| |+| ||||| Sbjct 439 QAKEHFGIEGDEGSTMVEESVAPSKATFLQH#EETTPSGKVETQSIAKPAIMR 490 |
| Strongylocentrotus purpuratus | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEHGSVALPAIMRSGASGPENF 463 | || ||+||+|| + |++|| ++ ++|# | + | + ||||+| +|| | +| | Sbjct 418 KGKDRMGLDGDDESLLFEENVSATRARIIQ#LQSSNKGHMTEGSVAMPGLMRPGGNGKSTF 477 |
| Caenorhabditis elegans | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEH---GSVALPAIMRSGASG 459 +++|| |+|||| |||||| |+| |+|++ # + ++| +| | ||+ ++|+ | Sbjct 432 RTQDHQGIEGDEGSTMLEDMVAPAKATLV-#-AHGQIGSGQHATDGLVAVRGVLRTPQGG 488 |
| Caenorhabditis briggsae | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNRVGKVEH---GSVALPAIMRSGASG 459 +++|| |+|||| |||||| |+| |+|++ # + ++| +| | ||+ ++|+ | Sbjct 426 RTQDHQGIEGDEGSTMLEDMVAPAKATLV-#-AHGQIGNGQHAQDGLVAVRGVLRTPQGG 482 |
| Podocoryne carnea | Query 404 KSKDHFGLEGDEESTMLEDSVSPKKSTVLQ#QQYNR 438 ++ | + + ||+| +||+ | | |+||||#+| || Sbjct 421 RAHDMYENDVDEDSPILEEHVMPNKATVLQ#RQNNR 455 |
* References
[PubMed ID: 10349636] Carninci P, Hayashizaki Y, High-efficiency full-length cDNA cloning. Methods Enzymol. 1999;303:19-44.
[PubMed ID: 11042159] ... Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y, Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Genome Res. 2000 Oct;10(10):1617-30.
[PubMed ID: 11076861] ... Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y, RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Genome Res. 2000 Nov;10(11):1757-71.
[PubMed ID: 11217851] ... Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schonbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90.
[PubMed ID: 12466851] ... Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schonbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002 Dec 5;420(6915):563-73.
[PubMed ID: 16141072] ... Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schonbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, The transcriptional landscape of the mammalian genome. Science. 2005 Sep 2;309(5740):1559-63.
[PubMed ID: 16141073] ... Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engstrom PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, Antisense transcription in the mammalian transcriptome. Science. 2005 Sep 2;309(5740):1564-6.