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XSB0955 : jun oncogene [Bos taurus]

[ CaMP Format ]

This entry is computationally expanded from SB0086

* Basic Information

OrganismBos taurus (cattle)
Protein Namesjun oncogene; v-jun avian sarcoma virus 17 oncogene homolog; activator protein 1
Gene NamesJUN; jun oncogene
Gene Locus3; chromosome 3
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001071295 NM_001077827 280831 Q08DH1 N/A N/A N/A bta:280831

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 303 aa

Average Mass: 33.321 kDa

Monoisotopic Mass: 33.300 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Jun 1. 5213362.67.3e-106
--- cleavage 62 (inside Jun 5..213) ---
--- cleavage 90 (inside Jun 5..213) ---
--- cleavage 42 (inside Jun 5..213) ---
bZIP_1 1. 22228584.92.9e-22

3. Sequence Information

Fasta Sequence: XSB0955.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

3 [sites]

Cleavage sites (±10aa)

[Site 1] LRAKNSDLLT62-SPDVGLLKLA

Thr62 Ser

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Leu53Arg54Ala55Lys56Asn57Ser58Asp59Leu60Leu61Thr62
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ser63Pro64Asp65Val66Gly67Leu68Leu69Lys70Leu71Ala72

Sequence conservation (by blast)

[Site 2] IQSSNGHITT90-TPTPTQFLCP

Thr90 Thr

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ile81Gln82Ser83Ser84Asn85Gly86His87Ile88Thr89Thr90
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Thr91Pro92Thr93Pro94Thr95Gln96Phe97Leu98Cys99Pro100

Sequence conservation (by blast)

[Site 3] ILKQSMTLNL42-ADPVGSLKPH

Leu42 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ile33Leu34Lys35Gln36Ser37Met38Thr39Leu40Asn41Leu42
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala43Asp44Pro45Val46Gly47Ser48Leu49Lys50Pro51His52

Sequence conservation (by blast)

* References

[PubMed ID: 18545934] Chowdhury TT, Salter DM, Bader DL, Lee DA, Signal transduction pathways involving p38 MAPK, JNK, NFkappaB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1beta and dynamic compression. Inflamm Res. 2008 Jul;57(7):306-13.

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