XSB2240 : FBJ osteosarcoma oncogene [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0064
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | Proto-oncogene protein c-fos; Cellular oncogene fos; FBJ osteosarcoma oncogene |
| Gene Names | Fos; FBJ osteosarcoma oncogene |
| Gene Locus | 12 40.0 cM; chromosome 12 |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 380 aa
Average Mass: 40.838 kDa
Monoisotopic Mass: 40.813 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| DUF1602 1. | 2 | 33 | -8.3 | 9.7 |
| --- cleavage 90 --- | ||||
| bZIP_1 1. | 135 | 198 | 37.7 | 4.7e-08 |
| Keratin_B2 1. | 216 | 369 | -104.1 | 8.9 |
3. Sequence Information
Fasta Sequence: XSB2240.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] LVSSVAPSQT90-RAPHPYGLPT
Thr90 
Arg
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Leu81 | Val82 | Ser83 | Ser84 | Val85 | Ala86 | Pro87 | Ser88 | Gln89 | Thr90 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Arg91 | Ala92 | Pro93 | His94 | Pro95 | Tyr96 | Gly97 | Leu98 | Pro99 | Thr100 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| IPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTQSAGAYARAGMVKTVSGGRA |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 122.00 | 8 | unnamed protein product |
| 2 | N/A | 120.00 | 7 | F |
| 3 | Murine osteosarcoma virus | 120.00 | 2 | FOS |
| 4 | Murine sarcoma virus | 117.00 | 1 | FOS_MSVFB p55-v-fos-transforming protein emb |
| 5 | Phodopus roborowski | 116.00 | 3 | FOS_PHORO Proto-oncogene protein c-fos (Cellular o |
| 6 | Mesocricetus auratus | 116.00 | 1 | FOS_MESAU Proto-oncogene protein c-fos (Cellular o |
| 7 | Rattus norvegicus | 115.00 | 5 | FBJ murine osteosarcoma viral oncogene homolog |
| 8 | Cricetulus griseus | 115.00 | 1 | FOS_CRIGR Proto-oncogene protein c-fos (Cellular o |
| 9 | Canis familiaris | 114.00 | 8 | PREDICTED: similar to Proto-oncogene protein c-fos |
| 10 | Phodopus sungorus | 114.00 | 3 | proto-oncogene protein c-FOS |
| 11 | Phodopus campbelli | 114.00 | 2 | FOS_PHOCM Proto-oncogene protein c-fos (Cellular o |
| 12 | Sus scrofa | 113.00 | 1 | c-Fos protein |
| 13 | Bos taurus | 112.00 | 3 | murine FBJ osteosarcoma viral (v-fos) oncogene hom |
| 14 | Pan troglodytes | 110.00 | 4 | v-fos FBJ murine osteosarcoma viral oncogene homol |
| 15 | swine, anterior pituitary, Peptide, 380 aa | 110.00 | 1 | FOS_PIG Proto-oncogene protein c-fos (Cellular onc |
| 16 | Spermophilus tridecemlineatus | 110.00 | 1 | c-fos |
| 17 | Homo sapiens | 108.00 | 7 | v-fos FBJ murine osteosarcoma viral oncogene homol |
| 18 | synthetic construct | 108.00 | 4 | v-fos FBJ murine osteosarcoma viral oncogene-like |
| 19 | Macaca mulatta | 108.00 | 4 | hypothetical protein LOC702077 |
| 20 | Felis catus | 108.00 | 3 | v-fos FBJ murine osteosarcoma viral oncogene homol |
| 21 | Ateles belzebuth chamek | 108.00 | 1 | similar to murine osteosarcoma viral oncogene |
| 22 | Monodelphis domestica | 94.00 | 3 | PREDICTED: similar to c-Fos protein |
| 23 | Gallus gallus | 75.90 | 2 | v-fos FBJ murine osteosarcoma viral oncogene homol |
| 24 | Xenopus laevis | 75.50 | 1 | MGC80305 protein |
| 25 | Coturnix coturnix | 75.50 | 1 | AF364329_1 c-fos proto-oncogene |
| 26 | Xenopus tropicalis | 75.10 | 1 | FBJ murine osteosarcoma viral oncogene homolog |
| 27 | Eublepharis macularius | 60.10 | 1 | fos proto-oncogene protein |
| 28 | Danio rerio | 57.00 | 11 | hypothetical protein LOC100009629 |
| 29 | Canis lupus familiaris | 57.00 | 1 | FBJ murine osteosarcoma viral oncogene homolog B |
| 30 | Dicentrarchus labrax | 55.80 | 1 | proto-oncogene protein c-Fos |
| 31 | Tetraodon nigroviridis | 55.50 | 5 | unnamed protein product |
| 32 | Rivulus marmoratus | 53.90 | 1 | c-fos |
| 33 | Oncorhynchus masou | 53.90 | 1 | c-Fos protein |
| 34 | Taenia crassiceps | 53.10 | 1 | c-fos |
| 35 | Taenia solium | 50.80 | 1 | c-fos |
| 36 | Takifugu rubripes | 49.70 | 5 | fra2 protein |
| 37 | Cyprinus carpio | 48.90 | 1 | FOS_CYPCA Proto-oncogene protein c-fos (Cellular o |
| 38 | Expression vector pGH/F2.2-327 | 48.90 | 1 | GSTmFra2/2-327 |
| 39 | Expression vector pGH/F2.2-242 | 48.90 | 1 | GSTmFra2/2-242 |
| 40 | Expression vector pGH/F2.2-163 | 48.90 | 1 | GSTmFra2/2-163 |
| 41 | Ctenopharyngodon idella | 48.50 | 1 | AF380155_1 c-Fos |
| 42 | Carassius auratus | 46.60 | 2 | c-fos |
| 43 | Oncorhynchus nerka | 43.10 | 1 | c-Fos type1 protein |
| 44 | Mus spretus | 42.40 | 1 | c-fos oncogene |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 |
| N/A | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||| ||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 37 IPTETAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 96 |
| Murine osteosarcoma virus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||| ||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 39 IPTETAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 98 |
| Murine sarcoma virus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 |||||| |||||||||||||||||||||||#||||||||||||||||||| |||||||||| Sbjct 61 IPTVTATSTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAEMVKTVSGGRA 120 |
| Phodopus roborowski | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||+|| | |||+||||||||||||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPSTGAYSRAGMVKTVSGGRA 120 |
| Mesocricetus auratus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||+|| | |||+||||||||||||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPSTGAYSRAGMVKTVSGGRA 120 |
| Rattus norvegicus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||||| | |||||||+|||+||||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTPSTGAYARAGVVKTMSGGRA 120 |
| Cricetulus griseus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||+|| |||||+|| |||||||||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPSAGAYSRAAMVKTVSGGRA 120 |
| Canis familiaris | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||+|| |||||+|||+|||++|||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPSAGAYSRAGVVKTMTGGRA 120 |
| Phodopus sungorus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||+|| |||+||||||||||||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPPTGAYSRAGMVKTVSGGRA 120 |
| Phodopus campbelli | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||+|| |||+||||||||||||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPPTGAYSRAGMVKTVSGGRA 120 |
| Sus scrofa | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||+|| |||||+|||+|||+ |||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPSAGAYSRAGVVKTMPGGRA 120 |
| Bos taurus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||+|| |||||+|||++||++|||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPSAGAYSRAGVMKTMTGGRA 120 |
| Pan troglodytes | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||| ||||||||||#|||||+|+|| |||||+|||+|||++|||| Sbjct 61 IPTVTAISTSPDLQWLVQPALVSSVAPSQT#RAPHPFGVPTPSAGAYSRAGVVKTMTGGRA 120 |
| swine, anterior pituitary, Peptide, 380 aa | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 |||||||| |||||||||||||||||||||#|||||||+|| |||||+||| |||+ |||| Sbjct 61 IPTVTAISISPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPSAGAYSRAGAVKTMPGGRA 120 |
| Spermophilus tridecemlineatus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||||||||||||||#|||||||+|| | |||+||| ||++|||| Sbjct 52 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPTPSTGAYSRAGAAKTMTGGRA 111 |
| Homo sapiens | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||| ||||||||||#|||||+|+| |||||+|||+|||++|||| Sbjct 61 IPTVTAISTSPDLQWLVQPALVSSVAPSQT#RAPHPFGVPAPSAGAYSRAGVVKTMTGGRA 120 |
| synthetic construct | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||| ||||||||||#|||||+|+| |||||+|||+|||++|||| Sbjct 61 IPTVTAISTSPDLQWLVQPALVSSVAPSQT#RAPHPFGVPAPSAGAYSRAGVVKTMTGGRA 120 |
| Macaca mulatta | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 ||||||||||||||||||| ||||||||||#|||||+|+|| |||||+|||+|||++| || Sbjct 61 IPTVTAISTSPDLQWLVQPALVSSVAPSQT#RAPHPFGVPTPSAGAYSRAGIVKTMTGSRA 120 |
| Felis catus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTV-SGGR 119 ||||||||||||||||||||||||||||||#|||||||+| |||||+|||+|||| +||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGVPAPSAGAYSRAGVVKTVTAGGR 120 Query 120 A 120 | Query 120 A 120 |
| Ateles belzebuth chamek | Query 62 PTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 |||||||||||||||||| ||||||||||#|||||+|+|| |||||+|||+|||++|||| Sbjct 1 PTVTAISTSPDLQWLVQPALVSSVAPSQT#RAPHPFGVPTPSAGAYSRAGVVKTMTGGRA 59 |
| Monodelphis domestica | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGR 119 |||||||||||||||||||||+||||||||#| ||||+ || |+|||+||| +||| Sbjct 61 IPTVTAISTSPDLQWLVQPTLISSVAPSQT#RV-HPYGVSAPSAAVYSRAGIVKTTAGGR 118 |
| Gallus gallus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQS-AGAYARAGMVKTVSG 117 +||||||||||||||||||||+||||||| #| ||||+| + ||+| ++| | Sbjct 61 VPTVTAISTSPDLQWLVQPTLISSVAPSQN#RG-HPYGVPAPAPPAAYSRPAVLKAPGG 117 |
| Xenopus laevis | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSG 117 +||||||||||||||||||||+|||||||+#|| |||| | |+|+ +|| +| Sbjct 59 VPTVTAISTSPDLQWLVQPTLISSVAPSQS#RA-HPYG----STSVYSRSAVVKGSTG 110 |
| Coturnix coturnix | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQS-AGAYARAGMVKTVSG 117 +||||||||||||||||||||+||||||| #| ||||+| + ||+| ++| | Sbjct 61 VPTVTAISTSPDLQWLVQPTLISSVAPSQN#RG-HPYGVPPPAPPAAYSRPAVLKAPGG 117 |
| Xenopus tropicalis | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSG 117 +||||||||||||||||||||+|||||||+#|| |||| | ||+|+ ++| +| Sbjct 59 VPTVTAISTSPDLQWLVQPTLISSVAPSQS#RA-HPYG----STPAYSRSSVMKGSAG 110 |
| Eublepharis macularius | Query 71 PDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKT 114 ||||||||| +||||||| #| ||| || | ||+|||+||| Sbjct 2 PDLQWLVQP--ISSVAPSQN#RT-HPYSLPAPSTTAYSRAGIVKT 42 |
| Danio rerio | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSA------GAYARAGMVKT 114 |||+ ||+|| ||||+||||+++|++ +#| |||||| | | | |++++ Sbjct 48 IPTINAITTSQDLQWMVQPTVITSMSNPYS#R-PHPYGLSVSSGPSLLGHTALTRPGVIRS 106 Query 115 VSGGR 119 + | Sbjct 107 IGDAR 111 |
| Canis lupus familiaris | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#R-------APHPYGLPTQSAGAYARAGMVK 113 +||||||+|| ||||||||||+||+| || #+ | || +| | |+ || Sbjct 55 VPTVTAITTSQDLQWLVQPTLISSMAQSQG#QPLASQPPAVDPYDMPGTS---YSTPGMSG 111 Query 114 TVSGG 118 ||| Sbjct 112 YSSGG 116 |
| Dicentrarchus labrax | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGM 111 |||||||||||||||+||| |+|||||| # ||| + + ||+| | Sbjct 58 IPTVTAISTSPDLQWMVQP-LISSVAPS--#HRAHPYS--SSPSPAYSRPAM 103 |
| Tetraodon nigroviridis | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYG---------LPTQSAGAYARAGM 111 +||||||||||||||+||| |||||||| #| ||| + + ++ |+|+ | Sbjct 56 VPTVTAISTSPDLQWMVQP-LVSSVAPS--#RRAHPYSPSPSYKRTVMRSAASKAHAKRGR 112 Query 112 VK 113 |+ Sbjct 113 VE 114 |
| Rivulus marmoratus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVS 116 |||||||||||||||+||| |+| |||| # ||| + + || |+ | | Sbjct 58 IPTVTAISTSPDLQWMVQP-LISLVAPS--#HRAHPYS--SSPSPAYPRSAMRSAAS 108 |
| Oncorhynchus masou | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGR 119 |||||||| |||+|||||| +|||||| # |+ || |+|| | | || Sbjct 60 IPTVTAISASPDMQWLVQP--ISSVAPSYR#AHPYSASPPT-----YSRAMRNKGHSSGR 111 |
| Taenia crassiceps | Query 89 QT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 +|#||||||||| + |||||||+|||+||||| Sbjct 97 KT#RAPHPYGLPP-ATGAYARAGVVKTMSGGRA 127 |
| Taenia solium | Query 89 QT#RAPHPYGLPTQSAGAYARAGMVKTVSGGRA 120 +|#||||||||| + ||||||+|||+||||| Sbjct 97 KT#RAPHPYGLPP-TGNAYARAGVVKTMSGGRA 127 |
| Takifugu rubripes | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSA------GAYARAGMVKT 114 |||+ ||+|| ||||+||||+++|++ +#|+ |||| + || |++++ Sbjct 57 IPTINAITTSQDLQWMVQPTVITSMSSPYS#RS-HPYGHHLTNGPGILGHNPLARPGVIRS 115 Query 115 VSGGR 119 + | Sbjct 116 IGDTR 120 |
| Cyprinus carpio | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RA----PHPY 96 +|||||||+ |||||+||| +||||||| # | |+|| Sbjct 48 VPTVTAISSCPDLQWMVQP-MVSSVAPSNG#GARSYNPNPY 86 |
| Expression vector pGH/F2.2-327 | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYG-LPTQSA----GAYARAGMVKTV 115 |||+ ||+|| ||||+||||+++|++ #|+ ||| || ++ | | |++||+ Sbjct 290 IPTINAITTSQDLQWMVQPTVITSMSNPYP#RS-HPYSPLPGLASVPGHMALPRPGVIKTI 348 |
| Expression vector pGH/F2.2-242 | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYG-LPTQSA----GAYARAGMVKTV 115 |||+ ||+|| ||||+||||+++|++ #|+ ||| || ++ | | |++||+ Sbjct 290 IPTINAITTSQDLQWMVQPTVITSMSNPYP#RS-HPYSPLPGLASVPGHMALPRPGVIKTI 348 |
| Expression vector pGH/F2.2-163 | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYG-LPTQSA----GAYARAGMVKTV 115 |||+ ||+|| ||||+||||+++|++ #|+ ||| || ++ | | |++||+ Sbjct 290 IPTINAITTSQDLQWMVQPTVITSMSNPYP#RS-HPYSPLPGLASVPGHMALPRPGVIKTI 348 |
| Ctenopharyngodon idella | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RA----PHPY 96 +|||||||+ |||||+||| ++|||||| # | |+|| Sbjct 48 VPTVTAISSCPDLQWMVQP-MISSVAPSNG#GARSYNPNPY 86 |
| Carassius auratus | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RA----PHPY 96 +| |||||+ |||||+||| +||||||| # | | || Sbjct 48 VPAVTAISSCPDLQWMVQP-MVSSVAPSNG#AARSYNPDPY 86 |
| Oncorhynchus nerka | Query 61 IPTVTAISTSPDLQWLVQPTLVSSVAPSQT#RAPHPYGLPTQSAGAYARAGMVKTVSGGR 119 |||||||| +|+| ||| | +||||| # |+ || | || | | || Sbjct 64 IPTVTAISATPNLHWLVHP--LSSVAPPYK#AHPYLATPPT-----YTRAMRNKGHSSGR 115 |
| Mus spretus | Query 71 PDLQWLVQPTLVSSVAPSQ 89 ||||||||||||||||||| Query 71 PDLQWLVQPTLVSSVAPSQ 89 |
* References
[PubMed ID: 19249353] Gilley R, March HN, Cook SJ, ERK1/2, but not ERK5, is necessary and sufficient for phosphorylation and activation of c-Fos. Cell Signal. 2009 Jun;21(6):969-77. Epub 2009 Feb 25.
[PubMed ID: 19092943] ... Golonzhka O, Liang X, Messaddeq N, Bornert JM, Campbell AL, Metzger D, Chambon P, Ganguli-Indra G, Leid M, Indra AK, Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation. J Invest Dermatol. 2009 Jun;129(6):1459-70. Epub 2008 Dec 18.
[PubMed ID: 19285436] ... Koga K, Takaesu G, Yoshida R, Nakaya M, Kobayashi T, Kinjyo I, Yoshimura A, Cyclic adenosine monophosphate suppresses the transcription of proinflammatory cytokines via the phosphorylated c-Fos protein. Immunity. 2009 Mar 20;30(3):372-83. Epub 2009 Mar 12.
[PubMed ID: 19191218] ... Yang DH, Smith ER, Cai KQ, Xu XX, C-Fos elimination compensates for disabled-2 requirement in mouse extraembryonic endoderm development. Dev Dyn. 2009 Mar;238(3):514-23.
[PubMed ID: 19079363] ... Wang X, Zhang Y, Xiao G, Gao X, Liu X, c-Fos enhances the survival of thymocytes during positive selection by upregulating Bcl-2. Cell Res. 2009 Mar;19(3):340-7.
[PubMed ID: 1465144] ... Wang ZQ, Ovitt C, Grigoriadis AE, Mohle-Steinlein U, Ruther U, Wagner EF, Bone and haematopoietic defects in mice lacking c-fos. Nature. 1992 Dec 24-31;360(6406):741-5.
[PubMed ID: 1423615] ... Johnson RS, Spiegelman BM, Papaioannou V, Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell. 1992 Nov 13;71(4):577-86.
[PubMed ID: 1383034] ... Tomomura M, Nakagawa K, Saheki T, Proto-oncogene c-jun and c-fos messenger RNAs increase in the liver of carnitine-deficient juvenile visceral steatosis (jvs) mice. FEBS Lett. 1992 Oct 12;311(1):63-6.
[PubMed ID: 1329091] ... Field SJ, Johnson RS, Mortensen RM, Papaioannou VE, Spiegelman BM, Greenberg ME, Growth and differentiation of embryonic stem cells that lack an intact c-fos gene. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9306-10.
[PubMed ID: 1406937] ... Clarke AR, Maandag ER, van Roon M, van der Lugt NM, van der Valk M, Hooper ML, Berns A, te Riele H, Requirement for a functional Rb-1 gene in murine development. Nature. 1992 Sep 24;359(6393):328-30.