logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2245 : Flnc protein [Mus musculus]

[ CaMP Format ]

This entry is computationally expanded from SB0092

* Basic Information

OrganismMus musculus (house mouse)
Protein NamesFlnc protein
Gene NamesFlnc
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAI58129 N/A 68794 B2RY80_MOUSE N/A N/A N/A mmu:68794

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 2693 aa

Average Mass: 287.365 kDa

Monoisotopic Mass: 287.186 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
CH 1. 38143109.89.2e-30
CH 2. 161263101.82.3e-27
Filamin 1. 273366128.22.6e-35
Filamin 2. 373466126.87.2e-35
Filamin 3. 472563134.04.7e-37
Filamin 4. 569656120.36.4e-33
Filamin 5. 665756147.34.6e-41
Filamin 6. 762859135.12.2e-37
Filamin 7. 865958125.32e-34
Filamin 8. 9641054110.17.3e-30
Filamin 9. 10601147151.52.5e-42
Filamin 10. 11531242149.21.3e-41
Filamin 11. 12481342123.18.9e-34
Filamin 12. 13481435158.32.2e-44
Filamin 13. 14411531145.91.3e-40
Filamin 14. 15371628139.01.5e-38
Filamin 15. 16341732100.17.5e-27
Filamin 16. 1742181926.35.4e-05
Filamin 17. 18241911156.48.4e-44
Filamin 18. 1912199821.70.00014
Filamin 19. 20062093151.42.8e-42
Filamin 20. 2184227141.82.7e-09
Filamin 21. 22792366137.93.2e-38
Filamin 22. 2373246186.78.4e-23
Filamin 23. 24702557125.32e-34
--- cleavage 2594 ---
Filamin 24. 26002689116.68e-32

3. Sequence Information

Fasta Sequence: XSB2245.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] SSSSRGASYS2594-SIPKFSSDAS

Ser2594 Ser

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ser2585Ser2586Ser2587Ser2588Arg2589Gly2590Ala2591Ser2592Tyr2593Ser2594
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ser2595Ile2596Pro2597Lys2598Phe2599Ser2600Ser2601Asp2602Ala2603Ser2604

Sequence conservation (by blast)

* References

[PubMed ID: 12477932] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.