XSB2250 : unnamed protein product [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0092
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | Putative uncharacterized protein |
| Gene Names | Flnc |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| BAE22565 | N/A | N/A | Q3UXJ8_MOUSE | N/A | N/A | N/A | mmu: |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 774 aa
Average Mass: 82.616 kDa
Monoisotopic Mass: 82.565 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Filamin 1. | 1 | 79 | 11.8 | 0.0011 |
| Filamin 2. | 87 | 174 | 151.4 | 2.8e-42 |
| Filamin 3. | 265 | 352 | 41.8 | 2.7e-09 |
| Filamin 4. | 360 | 447 | 137.9 | 3.2e-38 |
| Filamin 5. | 454 | 542 | 86.7 | 8.4e-23 |
| Filamin 6. | 551 | 638 | 125.3 | 2e-34 |
| --- cleavage 675 --- | ||||
| Filamin 7. | 681 | 770 | 116.6 | 8e-32 |
3. Sequence Information
Fasta Sequence: XSB2250.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] SSSSRGASYS675-SIPKFSSDAS
Ser675 
Ser
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ser666 | Ser667 | Ser668 | Ser669 | Arg670 | Gly671 | Ala672 | Ser673 | Tyr674 | Ser675 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser676 | Ile677 | Pro678 | Lys679 | Phe680 | Ser681 | Ser682 | Asp683 | Ala684 | Ser685 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LSGGHSLHETSTVLVETVTKSSSSRGASYSSIPKFSSDASKVVTRGPGLSQAFVGQKNSF |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 94.40 | 30 | PREDICTED: similar to Filamin-C (Gamma-filamin) (F |
| 2 | Mus musculus | 94.40 | 24 | PREDICTED: similar to Filamin-C (Gamma-filamin) (F |
| 3 | Canis familiaris | 94.40 | 21 | PREDICTED: similar to Filamin C (Gamma-filamin) (F |
| 4 | N/A | 94.40 | 16 | F |
| 5 | Pan troglodytes | 94.40 | 16 | PREDICTED: gamma filamin |
| 6 | Bos taurus | 94.40 | 6 | PREDICTED: similar to filamin, muscle isoform 2 |
| 7 | Rattus norvegicus | 94.40 | 5 | PREDICTED: similar to Filamin-C (Gamma-filamin) (F |
| 8 | Xenopus laevis | 87.00 | 5 | Unknown (protein for IMAGE:6940151) |
| 9 | Gallus gallus | 80.50 | 4 | cgABP260 |
| 10 | Danio rerio | 80.10 | 5 | LOC570288 protein |
| 11 | Tetraodon nigroviridis | 66.20 | 4 | unnamed protein product |
| 12 | Xenopus tropicalis | 58.90 | 1 | hypothetical protein LOC779840 |
| 13 | Oryctolagus cuniculus | 57.80 | 1 | FLNB_RABIT Filamin-B (FLN-B) (Beta-filamin) (Actin |
| 14 | Macaca mulatta | 56.20 | 8 | PREDICTED: filamin B, beta (actin binding protein |
| 15 | Sus scrofa | 56.20 | 2 | filamin B beta |
| 16 | Drosophila melanogaster | 54.30 | 8 | RE60544p |
| 17 | Monodelphis domestica | 52.40 | 1 | PREDICTED: similar to filamin B, beta (actin bindi |
| 18 | Anopheles gambiae str. PEST | 48.90 | 1 | ENSANGP00000003616 |
| 19 | Aedes aegypti | 48.90 | 1 | filamin, putative |
| 20 | Apis mellifera | 44.30 | 1 | PREDICTED: similar to cheerio CG3937-PB, isoform B |
| 21 | Strongylocentrotus purpuratus | 40.80 | 3 | PREDICTED: similar to filamin, partial |
| 22 | Euprymna scolopes | 40.00 | 1 | filamin |
| 23 | Caenorhabditis briggsae | 37.70 | 1 | Hypothetical protein CBG10541 |
| 24 | Caenorhabditis elegans | 37.40 | 2 | Y66H1B.2a |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||||||||||| # ||||||||||||||||||||||||||||| Sbjct 178 LSGGHSLHETSTVLVETVTKSSSSRGSSYS#SIPKFSSDASKVVTRGPGLSQAFVGQKNSF 237 |
| Mus musculus | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||||||||||| # ||||||||||||||||||||||||||||| Sbjct 646 LSGGHSLHETSTVLVETVTKSSSSRGASYS#SIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |
| Canis familiaris | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||||||||||| # ||||||||||||||||||||||||||||| Sbjct 351 LSGGHSLHETSTVLVETVTKSSSSRGSSYS#SIPKFSSDASKVVTRGPGLSQAFVGQKNSF 410 |
| N/A | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||||||||||| # ||||||||||||||||||||||||||||| Sbjct 2597 LSGGHSLHETSTVLVETVTKSSSSRGSSYS#SIPKFSSDASKVVTRGPGLSQAFVGQKNSF 2656 |
| Pan troglodytes | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||||||||||| # ||||||||||||||||||||||||||||| Sbjct 2443 LSGGHSLHETSTVLVETVTKSSSSRGSSYS#SIPKFSSDASKVVTRGPGLSQAFVGQKNSF 2502 |
| Bos taurus | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||||||||||| # ||||||||||||||||||||||||||||| Sbjct 2479 LSGGHSLHETSTVLVETVTKSSSSRGSSYS#SIPKFSSDASKVVTRGPGLSQAFVGQKNSF 2538 |
| Rattus norvegicus | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||||||||||| # ||||||||||||||||||||||||||||| Sbjct 2517 LSGGHSLHETSTVLVETVTKSSSSRGASYS#SIPKFSSDASKVVTRGPGLSQAFVGQKNSF 2576 |
| Xenopus laevis | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||||||||||| # |||||||||||+||||||+|||||||+| Sbjct 53 LSGGHSLHETSTVLVETVTKSSASVGEYGM#AGPKFSSDASKVVSRGPGLSKAFVGQKNTF 112 |
| Gallus gallus | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||+|||||||+ # +||||||||||| |||||| ||||||| | Sbjct 2531 LSGGHSLHETSSVLVETVTRGALGPPGFGT#-LPKFSSDASKVVARGPGLSTAFVGQKNHF 2589 |
| Danio rerio | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||||||||+|||||||| # +|||||||||||+|| |||+||+||||+| Sbjct 91 LSGGHSLHETSSVLVETVTKSSSVAGSFST#-LPKFSSDASKVVSRGAGLSKAFIGQKNTF 149 |
| Tetraodon nigroviridis | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 || || | |||+||||||+| # ||||||||+|+ || |||+||+ ||||| Sbjct 2744 LSSGHGLRETSSVLVETVSKSTAKGAAFAS#-FPKFSSDASQVLLRGAGLSKAFISQKNSF 2802 |
| Xenopus tropicalis | Query 650 HSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||+|+| |++||| # |+ +||||||| +| ||++||||||||| Sbjct 95 HSLHESSSVFVDSVTKSEAFTQHAAA#--PRIASDASKVVAKGLGLNKAFVGQKNSF 148 |
| Oryctolagus cuniculus | Query 646 LSGGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 | | | +|||++|||+||+ # ||| ||||||| ++| |||+||||||+|| Sbjct 168 LVGPGSTNETSSILVESVTRSSTETCYSA-#-IPKASSDASKVTSKGAGLSKAFVGQKSSF 225 |
| Macaca mulatta | Query 651 SLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 | +|||++|||+||+ # ||| ||||||| ++| |||+||||||+|| Sbjct 2296 SANETSSILVESVTRSSTETCYSA-#-IPKASSDASKVTSKGAGLSKAFVGQKSSF 2348 |
| Sus scrofa | Query 651 SLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 | +|||++|||+||+ # ||| ||||||| ++| |||+||||||+|| Sbjct 131 SANETSSILVESVTRSSTETCYSA-#-IPKASSDASKVTSKGAGLSKAFVGQKSSF 183 |
| Drosophila melanogaster | Query 654 ETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||||+|||| | # +| | |||||||++| || +|++|++| | Sbjct 719 ETSTVIVETVQKVAKGGKNTGV#HLPTFKSDASKVVSKGMGLKKAYIGKQNQF 770 |
| Monodelphis domestica | Query 651 SLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 | +|||++|||+||+ # +|| ||||||| ++| || +||||||++| Sbjct 37 SANETSSILVESVTRSSTETCYSA-#-VPKASSDASKVTSKGAGLVKAFVGQKSTF 89 |
| Anopheles gambiae str. PEST | Query 654 ETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||+|+|||| | # +| | |||||+ ++| || +|++|++| | Sbjct 2293 ETSSVIVETVAKVSKGGNRTGV#ILPIFKSDASKIQSKGMGLKKAYMGKQNQF 2344 |
| Aedes aegypti | Query 654 ETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||+|+|||| | # +| | |||||| ++| || +|++|++| | Sbjct 2235 ETSSVVVETVAKVSKGGNRTGV#ILPIFKSDASKVQSKGMGLKKAYLGKQNQF 2286 |
| Apis mellifera | Query 654 ETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 |||+++|||| | # +| | |||||| ++| || +|++|++| | Sbjct 683 ETSSIVVETVQKISKAKQVGPV#-LPLFKSDASKVTSKGMGLKKAYLGKQNVF 733 |
| Strongylocentrotus purpuratus | Query 654 ETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 ||+ |+|||+ | # | |+|||||||+ | || ++|+ +|+ | Sbjct 533 ETAQVMVETIVKTTTTTGFQA-#--PVFTSDASKVVSSGMGLKKSFLNKKSQF 581 |
| Euprymna scolopes | Query 649 GHS--LHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVG 700 ||+ || ++|+|||||| # | | ||||||| | || |+ | Sbjct 78 GHASGFHEQASVVVETVTKTSTTTRFSG-#-IQNFQSDASKVVANGAGLKTAYPG 129 |
| Caenorhabditis briggsae | Query 648 GGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 ||+ +||| | ++ | | # +|+++ ||+|| +| ||++ | |+ +| Sbjct 1241 GGNGYNETSHVKIDAVAKTSKGTVAV--#-VPEYAGDAAKVTAKGAGLNKFFPGRPAAF 1295 |
| Caenorhabditis elegans | Query 648 GGHSLHETSTVLVETVTKXXXXXXXXXX#XIPKFSSDASKVVTRGPGLSQAFVGQKNSF 705 ||+ +||| | ++ | | # +|++ ||+|| +| ||++ | |+ +| Sbjct 775 GGNGYNETSHVKIDAVAKTSKGTVAV--#-VPEYQGDAAKVTAKGAGLNKFFPGRPAAF 829 |
* References
[PubMed ID: 10349636] Carninci P, Hayashizaki Y, High-efficiency full-length cDNA cloning. Methods Enzymol. 1999;303:19-44.
[PubMed ID: 11042159] ... Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y, Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Genome Res. 2000 Oct;10(10):1617-30.
[PubMed ID: 11076861] ... Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y, RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Genome Res. 2000 Nov;10(11):1757-71.
[PubMed ID: 11217851] ... Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schonbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90.
[PubMed ID: 12466851] ... Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, Nogami A, Schonbach C, Gojobori T, Baldarelli R, Hill DP, Bult C, Hume DA, Quackenbush J, Schriml LM, Kanapin A, Matsuda H, Batalov S, Beisel KW, Blake JA, Bradt D, Brusic V, Chothia C, Corbani LE, Cousins S, Dalla E, Dragani TA, Fletcher CF, Forrest A, Frazer KS, Gaasterland T, Gariboldi M, Gissi C, Godzik A, Gough J, Grimmond S, Gustincich S, Hirokawa N, Jackson IJ, Jarvis ED, Kanai A, Kawaji H, Kawasawa Y, Kedzierski RM, King BL, Konagaya A, Kurochkin IV, Lee Y, Lenhard B, Lyons PA, Maglott DR, Maltais L, Marchionni L, McKenzie L, Miki H, Nagashima T, Numata K, Okido T, Pavan WJ, Pertea G, Pesole G, Petrovsky N, Pillai R, Pontius JU, Qi D, Ramachandran S, Ravasi T, Reed JC, Reed DJ, Reid J, Ring BZ, Ringwald M, Sandelin A, Schneider C, Semple CA, Setou M, Shimada K, Sultana R, Takenaka Y, Taylor MS, Teasdale RD, Tomita M, Verardo R, Wagner L, Wahlestedt C, Wang Y, Watanabe Y, Wells C, Wilming LG, Wynshaw-Boris A, Yanagisawa M, Yang I, Yang L, Yuan Z, Zavolan M, Zhu Y, Zimmer A, Carninci P, Hayatsu N, Hirozane-Kishikawa T, Konno H, Nakamura M, Sakazume N, Sato K, Shiraki T, Waki K, Kawai J, Aizawa K, Arakawa T, Fukuda S, Hara A, Hashizume W, Imotani K, Ishii Y, Itoh M, Kagawa I, Miyazaki A, Sakai K, Sasaki D, Shibata K, Shinagawa A, Yasunishi A, Yoshino M, Waterston R, Lander ES, Rogers J, Birney E, Hayashizaki Y, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002 Dec 5;420(6915):563-73.
[PubMed ID: 16141072] ... Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schonbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, The transcriptional landscape of the mammalian genome. Science. 2005 Sep 2;309(5740):1559-63.
[PubMed ID: 16141073] ... Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engstrom PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, Antisense transcription in the mammalian transcriptome. Science. 2005 Sep 2;309(5740):1564-6.