XSB2264 : calpain isoform Lp85 [Rattus norvegicus]
[ CaMP Format ]
This entry is computationally expanded from SB0104
* Basic Information
| Organism | Rattus norvegicus (Norway rat) |
| Protein Names | calpain isoform Lp85 |
| Gene Names | Capn3 |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| AAC15423 | N/A | N/A | O70376_RAT | N/A | N/A | N/A | rno: |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 737 aa
Average Mass: 85.130 kDa
Monoisotopic Mass: 85.076 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Cementoin 1. | 22 | 38 | 7.7 | 4 |
| Peptidase_C2 1. | 50 | 349 | 765.5 | 3.9e-227 |
| --- cleavage 274 (inside Peptidase_C2 50..349) --- | ||||
| --- cleavage 296 (inside Peptidase_C2 50..349) --- | ||||
| --- cleavage 322 (inside Peptidase_C2 50..349) --- | ||||
| Calpain_III 1. | 360 | 514 | 370.9 | 2.3e-108 |
| efhand 1. | 541 | 568 | 0.6 | 18 |
| efhand 2. | 612 | 640 | 28.5 | 2.6e-05 |
| efhand 3. | 642 | 670 | 27.4 | 5.8e-05 |
| efhand 4. | 707 | 734 | 9.1 | 2.2 |
3. Sequence Information
Fasta Sequence: XSB2264.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
3 [sites]
Cleavage sites (±10aa)
[Site 1] GHAYSVTGLE274-EALFKGEKVK
Glu274 
Glu
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gly265 | His266 | Ala267 | Tyr268 | Ser269 | Val270 | Thr271 | Gly272 | Leu273 | Glu274 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Glu275 | Ala276 | Leu277 | Phe278 | Lys279 | Gly280 | Glu281 | Lys282 | Val283 | Lys284 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| SIDTIVPVQYETRMACGLVKGHAYSVTGLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDG |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 129.00 | 37 | calpain 3 |
| 2 | Canis familiaris | 129.00 | 25 | PREDICTED: similar to calpain 3 isoform c isoform |
| 3 | Rattus norvegicus | 129.00 | 15 | calpain isoform Lp85 |
| 4 | Oryctolagus cuniculus | 127.00 | 1 | calpain 3, (p94) |
| 5 | Sus scrofa | 125.00 | 4 | lens-specific calpain Lp82 |
| 6 | N/A | 124.00 | 14 | 1 |
| 7 | Bos taurus | 122.00 | 12 | lens-specific calpain Lp82 |
| 8 | Homo sapiens | 120.00 | 43 | calpain 3 isoform c |
| 9 | Macaca mulatta | 120.00 | 3 | PREDICTED: calpain 3 |
| 10 | Macaca fascicularis | 120.00 | 2 | CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (C |
| 11 | Ovis aries | 120.00 | 2 | skeletal muscle-specific calpain |
| 12 | Gallus gallus | 105.00 | 9 | calpain 3, (p94) |
| 13 | Pan troglodytes | 99.00 | 13 | PREDICTED: similar to Calpain-3 (Calpain L3) (Calp |
| 14 | Tetraodon nigroviridis | 90.90 | 8 | unnamed protein product |
| 15 | Oncorhynchus mykiss | 90.90 | 4 | gill-specific calpain |
| 16 | Danio rerio | 89.00 | 23 | calpain 3, (p94) |
| 17 | Xenopus laevis | 80.50 | 11 | MGC83034 protein |
| 18 | Monodelphis domestica | 79.30 | 6 | PREDICTED: similar to digestive tract-specific cal |
| 19 | Xenopus tropicalis | 75.90 | 6 | calpain 5 |
| 20 | Bos grunniens | 72.40 | 1 | micromolar calcium-activated neutral protease 1 la |
| 21 | Caenorhabditis elegans | 71.60 | 1 | CaLPain family member (clp-6) |
| 22 | Coturnix coturnix | 70.90 | 1 | quail calpain |
| 23 | Pongo pygmaeus | 70.90 | 1 | CAN1_PONPY Calpain-1 catalytic subunit (Calpain-1 |
| 24 | synthetic construct | 70.50 | 1 | Homo sapiens calpain 1, (mu/I) large subunit |
| 25 | Strongylocentrotus purpuratus | 68.90 | 5 | PREDICTED: similar to calpain B isoform 2 |
| 26 | Stizostedion vitreum vitreum | 68.60 | 1 | putative calpain-like protein |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 |
| Canis familiaris | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 |
| Rattus norvegicus | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 |
| Oryctolagus cuniculus | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 ||||||||||||||||||||||||||||||#| |||||||||||||||||||||||||||| Sbjct 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#ETLFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 |
| Sus scrofa | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 |||||||||+||||||||||||||||||||#||||||||||||||||||||||||||||| Sbjct 245 SIDTIVPVQFETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 |
| N/A | Query 248 TIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 |||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 248 TIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 |
| Bos taurus | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 ||| |||||+||||||||||||||||||||#|||+||||||||||||||||||||||||| Sbjct 245 SIDMIVPVQFETRMACGLVKGHAYSVTGLE#EALYKGEKVKLVRLRNPWGQVEWNGSWSD 303 |
| Homo sapiens | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 |||||+|||||||||||||+|||||||||+#| |||||||||||||||||||||||||| Sbjct 265 SIDTIIPVQYETRMACGLVRGHAYSVTGLD#EVPFKGEKVKLVRLRNPWGQVEWNGSWSD 323 |
| Macaca mulatta | Query 248 TIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 ||||||||||||||||+|||||||||+#| |||||||||||||||||||||||||||| Sbjct 316 TIVPVQYETRMACGLVRGHAYSVTGLD#EVLFKGEKVKLVRLRNPWGQVEWNGSWSDG 372 |
| Macaca fascicularis | Query 248 TIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 ||||||||||||||||+|||||||||+#| |||||||||||||||||||||||||||| Sbjct 316 TIVPVQYETRMACGLVRGHAYSVTGLD#EVLFKGEKVKLVRLRNPWGQVEWNGSWSDG 372 |
| Ovis aries | Query 248 TIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 |||||||||||||||||||||||||||#|||+||||||||||||||||||||||||| Sbjct 317 TIVPVQYETRMACGLVKGHAYSVTGLE#EALYKGEKVKLVRLRNPWGQVEWNGSWSD 372 |
| Gallus gallus | Query 248 TIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 ||+|+||||||+|||||||||||| +|#| +||||++||||||||||||||| ||| Sbjct 309 TIMPMQYETRMSCGLVKGHAYSVTAVE#ETTYKGEKMRLVRLRNPWGQVEWNGPWSD 364 |
| Pan troglodytes | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 ||| + | ||||||+|||||||||+#| ||||||||||||||||||||||||||| Sbjct 265 SIDVSGCGEGEGIMACGLVRGHAYSVTGLD#EVLFKGEKVKLVRLRNPWGQVEWNGSWSD 323 |
| Tetraodon nigroviridis | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#E---ALFKGEKVKLVRLRNPWGQVEWNGSW 301 |||++|| ++||| | ||||||||||| +|#| + | ||+||||||||||||||| | Sbjct 246 SIDSLVPARFETRTATGLVKGHAYSVTAVE#ECKPSQHKESKVRLVRLRNPWGQVEWNGPW 305 Query 302 SD 303 || Query 302 SD 303 |
| Oncorhynchus mykiss | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 ||| + | + | |||||||||+||||#| ++|+||||+|+|||||||||||+||| Sbjct 219 SIDITSSAESEAQTASGLVKGHAYSITGLE#EVNYRGKKVKLIRIRNPWGQVEWNGAWSD 277 |
| Danio rerio | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#E---ALFKGEKVKLVRLRNPWGQVEWNGSW 301 |||++|| ++||| | ||||||||||| +|#| + | +|+||||||||||||||| | Sbjct 246 SIDSLVPARFETRTATGLVKGHAYSVTAVE#ECKQSQQKESRVRLVRLRNPWGQVEWNGPW 305 Query 302 SD 303 || Query 302 SD 303 |
| Xenopus laevis | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 ||| + | + |||||||||+| +# |+|+||||+|+|||||||||||+||| Sbjct 233 SIDISSSSETEAKTPQGLVKGHAYSITATD#VVNFQGQKVKLIRIRNPWGQVEWNGAWSD 291 |
| Monodelphis domestica | Query 255 ETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 | + ||+|||||+|||+ #+ +||+||+|+|+||||||||||| ||| Sbjct 243 EAKTPFGLIKGHAYTVTGIN#QVNYKGQKVELIRVRNPWGQVEWNGPWSD 291 |
| Xenopus tropicalis | Query 255 ETRMACGLVKGHAYSVTGLE#E--------ALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 | ||||||||||||+|| + #+ | || ||++++|+|||||+ |||| ||| Sbjct 241 EARMACGLVKGHAYAVTDVR#KVRLGHGLLAFFKSEKLEMIRMRNPWGEREWNGPWSD 297 |
| Bos grunniens | Query 262 LVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 ||||||||||| +#+ ++|+ | |+|+|||||+||| |+|||| Sbjct 232 LVKGHAYSVTGAK#QVNYQGQMVNLIRMRNPWGEVEWTGAWSDG 274 |
| Caenorhabditis elegans | Query 251 PVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 | + | ++| |||+||||||||+ # ||| |+|+||||| |||| ||| Sbjct 354 PREKEAQLANGLVRGHAYSVTGVH#TVETDKEKVALLRIRNPWGDTEWNGDWSD 406 |
| Coturnix coturnix | Query 262 LVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSDG 304 |||||||||| +#+ ++|++ +|+|+||||||||| |+|||| Sbjct 261 LVKGHAYSVTAFK#DVNYRGQQEQLIRIRNPWGQVEWTGAWSDG 303 |
| Pongo pygmaeus | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 ||| + | ||||||||||| +#+ ++|+ | |+|+|||||+||| |+||| Sbjct 251 SIDISSVLDMEAITFKKLVKGHAYSVTGAK#QVNYRGQMVSLIRMRNPWGEVEWTGAWSD 309 |
| synthetic construct | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 ||| + | ||||||||||| +#+ ++|+ | |+|+|||||+||| |+||| Sbjct 251 SIDISSVLDMEAITFKKLVKGHAYSVTGAK#QVNYRGQVVSLIRMRNPWGEVEWTGAWSD 309 |
| Strongylocentrotus purpuratus | Query 255 ETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 | ++ ||+ ||||++| ++#+ || |+|+|+||||| ||||| ||| Sbjct 224 EAKLPSGLIAGHAYTITDVK#KVNVKGRDVRLIRIRNPWGAVEWNGRWSD 272 |
| Stizostedion vitreum vitreum | Query 245 SIDTIVPVQYETRMACGLVKGHAYSVTGLE#EALFKGEKVKLVRLRNPWGQVEWNGSWSD 303 ||| + | + ||||||||||| #+ +| ||+|+||||||||| |+||| Sbjct 242 SIDITSSSESEAVTSQKLVKGHAYSVTGTA#QVEHQGGTEKLIRIRNPWGQVEWTGAWSD 300 |
[Site 2] RLRNPWGQVE296-WNGSWSDGWK
Glu296 Trp
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Arg287 | Leu288 | Arg289 | Asn290 | Pro291 | Trp292 | Gly293 | Gln294 | Val295 | Glu296 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Trp297 | Asn298 | Gly299 | Ser300 | Trp301 | Ser302 | Asp303 | Gly304 | Trp305 | Lys306 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| AYSVTGLEEALFKGEKVKLVRLRNPWGQVEWNGSWSDGWKDWSFVDKDEKARLQHQVTED |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 132.00 | 33 | calpain 3 |
| 2 | N/A | 132.00 | 17 | 1 |
| 3 | Rattus norvegicus | 132.00 | 16 | calpain isoform Lp85 |
| 4 | Oryctolagus cuniculus | 131.00 | 1 | calpain 3, (p94) |
| 5 | Sus scrofa | 130.00 | 4 | lens-specific calpain Lp82 |
| 6 | Macaca mulatta | 130.00 | 4 | PREDICTED: calpain 3 |
| 7 | Macaca fascicularis | 130.00 | 1 | CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (C |
| 8 | Canis familiaris | 129.00 | 25 | PREDICTED: similar to calpain 3 isoform c isoform |
| 9 | Bos taurus | 128.00 | 11 | lens-specific calpain Lp82 |
| 10 | Ovis aries | 128.00 | 2 | skeletal muscle-specific calpain |
| 11 | Pan troglodytes | 127.00 | 12 | PREDICTED: similar to Calpain-3 (Calpain L3) (Calp |
| 12 | Homo sapiens | 124.00 | 47 | calpain 3 isoform c |
| 13 | Monodelphis domestica | 105.00 | 7 | PREDICTED: similar to ZP1-related protein |
| 14 | Gallus gallus | 98.60 | 7 | calpain 3, (p94) |
| 15 | Oncorhynchus mykiss | 86.30 | 4 | gill-specific calpain |
| 16 | Danio rerio | 83.60 | 24 | hypothetical protein LOC445107 |
| 17 | Tetraodon nigroviridis | 79.00 | 5 | unnamed protein product |
| 18 | Xenopus laevis | 76.60 | 12 | MGC83034 protein |
| 19 | Xenopus tropicalis | 76.30 | 6 | calpain 8 (nCL-2) |
| 20 | Coturnix coturnix | 71.60 | 1 | quail calpain |
| 21 | Pongo pygmaeus | 69.70 | 1 | CAN1_PONPY Calpain-1 catalytic subunit (Calpain-1 |
| 22 | Bos grunniens | 69.30 | 1 | micromolar calcium-activated neutral protease 1 la |
| 23 | synthetic construct | 69.30 | 1 | Homo sapiens calpain 1, (mu/I) large subunit |
| 24 | catalytic | 68.90 | 1 | Calpain 2, large |
| 25 | Caenorhabditis elegans | 68.20 | 3 | CaLPain family member (clp-6) |
| 26 | Stizostedion vitreum vitreum | 67.80 | 1 | putative calpain-like protein |
| 27 | Tribolium castaneum | 65.90 | 1 | PREDICTED: similar to calpain 8 |
| 28 | Strongylocentrotus purpuratus | 64.70 | 1 | PREDICTED: similar to calpain B isoform 2 |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |
| N/A | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |
| Rattus norvegicus | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |
| Oryctolagus cuniculus | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 ||||||||| ||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 267 AYSVTGLEETLFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |
| Sus scrofa | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 ||||||||||||||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDSWKDWSFVDKDEKARLQHQVTED 326 |
| Macaca mulatta | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |||||||+| ||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 335 AYSVTGLDEVLFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 394 |
| Macaca fascicularis | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |||||||+| ||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 335 AYSVTGLDEVLFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 394 |
| Canis familiaris | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 ||||||||||||||||||||||||||||||#||||||||||||||||| |||||||||||| Sbjct 287 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKAEKARLQHQVTED 346 |
| Bos taurus | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |||||||||||+||||||||||||||||||#||||||| |||||+|||||||||||||||| Sbjct 267 AYSVTGLEEALYKGEKVKLVRLRNPWGQVE#WNGSWSDSWKDWSYVDKDEKARLQHQVTED 326 |
| Ovis aries | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |||||||||||+||||||||||||||||||#||||||| |||||+|||||||||||||||| Sbjct 336 AYSVTGLEEALYKGEKVKLVRLRNPWGQVE#WNGSWSDSWKDWSYVDKDEKARLQHQVTED 395 |
| Pan troglodytes | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |||||||+| ||||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 287 AYSVTGLDEVLFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 346 |
| Homo sapiens | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |||||||+| |||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 287 AYSVTGLDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 346 |
| Monodelphis domestica | Query 278 FKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |||||||||||||||||||#|||||||||||| +||+||+||||||||| Sbjct 317 FKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWVLIDKEEKSRLQHQVTED 365 |
| Gallus gallus | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 ||||| +|| +||||++||||||||||||#||| ||| ++|+|+|++|| ||||++ || Sbjct 328 AYSVTAVEETTYKGEKMRLVRLRNPWGQVE#WNGPWSDKSEEWNFIDEEEKIRLQHKIAED 387 |
| Oncorhynchus mykiss | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |||+||||| ++|+||||+|+||||||||#|||+||| ++|+ +| || |+ +| Sbjct 241 AYSITGLEEVNYRGKKVKLIRIRNPWGQVE#WNGAWSDESREWNVIDSSEKKRILQNSMDD 300 |
| Danio rerio | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 ||||||+|| ++| ||+|+|+||||||||#||| ||| ++|+ +| || || +| Sbjct 253 AYSVTGVEEVNYRGAKVQLIRVRNPWGQVE#WNGPWSDNSREWTVIDSSEKKRLLQNSLDD 312 |
| Tetraodon nigroviridis | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQ 322 |||||| ++ ++|| |+|||+||||||||#|||+||| +| +| |++ || ++ Sbjct 269 AYSVTGADQVEYRGEAVQLVRIRNPWGQVE#WNGAWSDDSSEWRYVSSDDRERLTNR 324 |
| Xenopus laevis | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |||+| + |+|+||||+|+||||||||#|||+||| +|+ + || || +| Sbjct 255 AYSITATDVVNFQGQKVKLIRIRNPWGQVE#WNGAWSDNSSEWNIIGAAEKNRLSQASLDD 314 |
| Xenopus tropicalis | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQ 322 |||||| || |++| + ||+|+|||||+||#| | ||| +|+++| || | | Sbjct 264 AYSVTGAEEVLYRGRQEKLIRVRNPWGEVE#WTGPWSDTAPEWNYIDPKVKAALDKQ 319 |
| Coturnix coturnix | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTE 325 ||||| ++ ++|++ +|+|+||||||||#| |+|||| +| +| ++ || ++ + Sbjct 266 AYSVTAFKDVNYRGQQEQLIRIRNPWGQVE#WTGAWSDGSPEWDNIDPSDREELQQKMED 324 |
| Pongo pygmaeus | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQ 320 |||||| ++ ++|+ | |+|+|||||+||#| |+||| +|+ || |+ +|+ Sbjct 273 AYSVTGAKQVNYRGQMVSLIRMRNPWGEVE#WTGAWSDSSSEWNNVDPYERDQLR 326 |
| Bos grunniens | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQ 320 |||||| ++ ++|+ | |+|+|||||+||#| |+|||| +|+ || + +|+ Sbjct 237 AYSVTGAKQVNYQGQMVNLIRMRNPWGEVE#WTGAWSDGSSEWNGVDPYMREQLR 290 |
| synthetic construct | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQ 320 |||||| ++ ++|+ | |+|+|||||+||#| |+||| +|+ || |+ +|+ Sbjct 273 AYSVTGAKQVNYRGQVVSLIRMRNPWGEVE#WTGAWSDSSSEWNNVDPYERDQLR 326 |
| catalytic | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARL 319 |||||| || | ||+|+|||||+||#| | |+| |+ +| +|+ || Sbjct 292 AYSVTGAEEVESNGSLQKLIRIRNPWGEVE#WTGRWNDNCPSWNTIDPEERERL 344 |
| Caenorhabditis elegans | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 ||||||+ ||| |+|+||||| |#||| ||| | ||++++ +++ ++ || Sbjct 370 AYSVTGVHTVETDKEKVALLRIRNPWGDTE#WNGDWSDKSSLWEQVDQEQREKMEFRIKED 429 |
| Stizostedion vitreum vitreum | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQ 322 |||||| + +| ||+|+||||||||#| |+||| | + +++ || |+ Sbjct 264 AYSVTGTAQVEHQGGTEKLIRIRNPWGQVE#WTGAWSDNSMQWRRISSEDRERLSHR 319 |
| Tribolium castaneum | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARL 319 |||+||| + | + |+|+||||| ||#||| ||| || | |+ | +| Sbjct 282 AYSITGLYTSQLKNVTIHLIRVRNPWGSVE#WNGPWSDNSVCWSLVPKETKQKL 334 |
| Strongylocentrotus purpuratus | Query 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARL 319 ||++| +++ || |+|+|+||||| ||#||| ||| ++| +++ |+ | Sbjct 236 AYTITDVKKVNVKGRDVRLIRIRNPWGAVE#WNGRWSDNAREWDDINQRERKNL 288 |
[Site 3] KDEKARLQHQ322-VTEDGEFWMS
Gln322 Val
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Lys313 | Asp314 | Glu315 | Lys316 | Ala317 | Arg318 | Leu319 | Gln320 | His321 | Gln322 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Val323 | Thr324 | Glu325 | Asp326 | Gly327 | Glu328 | Phe329 | Trp330 | Met331 | Ser332 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| GQVEWNGSWSDGWKDWSFVDKDEKARLQHQVTEDGEFWMSYDDFVYHFTKLEICNLTADA |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 138.00 | 33 | calpain 3 |
| 2 | N/A | 138.00 | 21 | 1 |
| 3 | Rattus norvegicus | 138.00 | 16 | calpain isoform Lp85 |
| 4 | Macaca mulatta | 136.00 | 4 | PREDICTED: calpain 3 |
| 5 | Macaca fascicularis | 136.00 | 1 | CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (C |
| 6 | Oryctolagus cuniculus | 136.00 | 1 | calpain 3, (p94) |
| 7 | Sus scrofa | 135.00 | 4 | lens-specific calpain Lp82 |
| 8 | Canis familiaris | 134.00 | 22 | PREDICTED: similar to calpain 3 isoform c isoform |
| 9 | Bos taurus | 134.00 | 10 | lens-specific calpain Lp82 |
| 10 | Ovis aries | 134.00 | 2 | skeletal muscle-specific calpain |
| 11 | Homo sapiens | 133.00 | 38 | calpain 3 isoform c |
| 12 | Pan troglodytes | 133.00 | 11 | PREDICTED: similar to Calpain-3 (Calpain L3) (Calp |
| 13 | Monodelphis domestica | 125.00 | 5 | PREDICTED: similar to ZP1-related protein |
| 14 | Gallus gallus | 100.00 | 7 | calpain 3, (p94) |
| 15 | Danio rerio | 89.70 | 19 | calpain 3, (p94) |
| 16 | Tetraodon nigroviridis | 84.70 | 6 | unnamed protein product |
| 17 | Oncorhynchus mykiss | 84.70 | 3 | calpain 1 catalytic subunit |
| 18 | Xenopus laevis | 84.00 | 9 | MGC83034 protein |
| 19 | Coturnix coturnix | 80.10 | 1 | quail calpain |
| 20 | Stizostedion vitreum vitreum | 79.70 | 1 | putative calpain-like protein |
| 21 | Caenorhabditis elegans | 79.30 | 4 | CaLPain family member (clp-7) |
| 22 | Caenorhabditis briggsae | 78.60 | 2 | Hypothetical protein CBG13923 |
| 23 | Xenopus tropicalis | 77.00 | 5 | CAPN2 protein |
| 24 | Pongo pygmaeus | 76.60 | 1 | CAN1_PONPY Calpain-1 catalytic subunit (Calpain-1 |
| 25 | catalytic | 76.60 | 1 | Calpain 2, large |
| 26 | synthetic construct | 76.60 | 1 | Homo sapiens calpain 1, (mu/I) large subunit |
| 27 | Bos taurus x Bos indicus | 75.10 | 1 | micromolar calcium activated neutral protease 1 |
| 28 | Bos grunniens | 74.70 | 2 | calpain 2 |
| 29 | Drosophila melanogaster | 73.60 | 7 | CAA55297.1 |
| 30 | Schistosoma japonicum | 69.70 | 1 | SJCHGC01809 protein |
| 31 | Anopheles gambiae | 69.70 | 1 | calpain |
| 32 | Tribolium castaneum | 69.70 | 1 | PREDICTED: similar to CG8107-PA |
| 33 | Anopheles gambiae str. PEST | 69.70 | 1 | ENSANGP00000032073 |
| 34 | Aedes aegypti | 69.30 | 2 | calpain, putative |
| 35 | Homarus americanus | 69.30 | 1 | muscle-specific calpain |
| 36 | Gecarcinus lateralis | 67.80 | 2 | muscle-specific calpain |
| 37 | Drosophila pseudoobscura | 67.40 | 1 | GA20829-PA |
| 38 | Schistosoma haematobium | 67.00 | 1 | calpain |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 |
| N/A | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 |
| Rattus norvegicus | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 |
| Macaca mulatta | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||||||||||||||||||||||#|||||||||||+||+||||||||||||||| Sbjct 361 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 420 |
| Macaca fascicularis | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||||||||||||||||||||||#|||||||||||+||+||||||||||||||| Sbjct 361 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 420 |
| Oryctolagus cuniculus | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||||||||||||||||||||||#|||||||||||||||+|||||||||||||| Sbjct 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVFHFTKLEICNLTADA 352 |
| Sus scrofa | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||| ||||||||||||||||||#||||||||||||||+||||||||||||||| Sbjct 293 GQVEWNGSWSDSWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFIYHFTKLEICNLTADA 352 |
| Canis familiaris | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||||||||||||| ||||||||#||||||||||||||+||||||||||||||| Sbjct 281 GQVEWNGSWSDGWKDWSFVDKAEKARLQHQ#VTEDGEFWMSYDDFIYHFTKLEICNLTADA 340 |
| Bos taurus | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||| |||||+||||||||||||#||||||||||||||+||||||||||||||| Sbjct 293 GQVEWNGSWSDSWKDWSYVDKDEKARLQHQ#VTEDGEFWMSYDDFIYHFTKLEICNLTADA 352 |
| Ovis aries | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||| |||||+||||||||||||#||||||||||||||+||||||||||||||| Sbjct 362 GQVEWNGSWSDSWKDWSYVDKDEKARLQHQ#VTEDGEFWMSYDDFIYHFTKLEICNLTADA 421 |
| Homo sapiens | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||| ||||||||||||||||||#|||||||||||+||+||||||||||||||| Sbjct 313 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 372 |
| Pan troglodytes | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||||||| ||||||||||||||||||#|||||||||||+||+||||||||||||||| Sbjct 313 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 372 |
| Monodelphis domestica | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 |||||||||||||||| +||+||+|||||#|||||||||||+||+|+||||||||||||| Sbjct 332 GQVEWNGSWSDGWKDWVLIDKEEKSRLQHQ#VTEDGEFWMSYEDFMYNFTKLEICNLTADA 391 |
| Gallus gallus | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTAD 351 ||||||| ||| ++|+|+|++|| ||||+#+ ||||||+| +||+ ||||||||||| | Sbjct 354 GQVEWNGPWSDKSEEWNFIDEEEKIRLQHK#IAEDGEFWISLEDFMRHFTKLEICNLTPD 412 |
| Danio rerio | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||||| ||| |+| + | || +|| |# ||||||||++|| ++||+|||||| || Sbjct 297 GQVEWNGPWSDNSKEWESLSKAEKEKLQQQ#NAEDGEFWMSFEDFKKNYTKIEICNLTPDA 356 |
| Tetraodon nigroviridis | Query 293 GQVEWNGSWSD----------GWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTK 342 ||||||| ||| |+|| + | || +| ||# ||||||||++|| ++|| Sbjct 297 GQVEWNGPWSDKNRPFRLLRNSSKEWSTLSKAEKEKLHHQ#SAEDGEFWMSFEDFKKNYTK 356 Query 343 LEICNLTADA 352 +|||||| || Sbjct 357 IEICNLTPDA 366 |
| Oncorhynchus mykiss | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 |++|| |+||| ++| ||+ + |||++# +||||||||+ ||+ ||+|||||||||| Sbjct 294 GEIEWTGAWSDNSREWESVDRSVRGRLQNR#-SEDGEFWMSFSDFLREFTRLEICNLTADA 352 |
| Xenopus laevis | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 |||||||+||| +|+ + || || # +|||||| ++|| || |||||||| || Sbjct 281 GQVEWNGAWSDNSSEWNIIGAAEKNRLSQA#SLDDGEFWMDFEDFKRHFDKLEICNLTPDA 340 |
| Coturnix coturnix | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||| |+|||| +| +| ++ || +#+ ||||||||+ ||+ |++||||||| || Sbjct 292 GQVEWTGAWSDGSPEWDNIDPSDREELQQK#M-EDGEFWMSFRDFMREFSRLEICNLTPDA 350 |
| Stizostedion vitreum vitreum | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||| |+||| | + +++ || |+# +||||||||+ ||+ |+ +||||||| || Sbjct 290 GQVEWTGAWSDNSMQWRRISSEDRERLSHR#-SEDGEFWMSFADFLRHYDRLEICNLTPDA 348 |
| Caenorhabditis elegans | Query 296 EWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTAD 351 ||||+|||| +|| || ++ ++ |# +|||||||+|||+ +||++| |||+|| Sbjct 553 EWNGAWSDGSSEWSQVDPQQREQMGVQ#FAKDGEFWMSFDDFMTNFTQMECCNLSAD 608 |
| Caenorhabditis briggsae | Query 296 EWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTAD 351 ||||+|||| +|+ +| ++ ++ |# +|||||||+|||+ +||++| |||+|| Sbjct 552 EWNGAWSDGASEWNQIDPSQREQMNVQ#FAKDGEFWMSFDDFMSNFTQMECCNLSAD 607 |
| Xenopus tropicalis | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||| |+||| +|+ || |+ || +#+ ||||||||+ +|+ |++||||||| || Sbjct 292 GQVEWTGAWSDNSSEWNEVDPSEQEDLQLK#M-EDGEFWMSFQEFLRQFSRLEICNLTPDA 350 |
| Pongo pygmaeus | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 |+||| |+||| +|+ || |+ +|+ +#+ ||||||||+ ||+ ||+||||||| || Sbjct 299 GEVEWTGAWSDSSSEWNNVDPYERDQLRVK#M-EDGEFWMSFRDFMREFTRLEICNLTPDA 357 |
| catalytic | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTAD 351 |+||| | |+| |+ +| +|+ || +# ||||||||+ ||+ |+++||||||| | Sbjct 318 GEVEWTGRWNDNCPSWNTIDPEERERLTRR#-HEDGEFWMSFSDFLRHYSRLEICNLTPD 375 |
| synthetic construct | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 |+||| |+||| +|+ || |+ +|+ +#+ ||||||||+ ||+ ||+||||||| || Sbjct 299 GEVEWTGAWSDSSSEWNNVDPYERDQLRVK#M-EDGEFWMSFRDFMREFTRLEICNLTPDA 357 |
| Bos taurus x Bos indicus | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTAD 351 |+||| |+|||| +|+ || + +|+ +#+ ||||||||+ ||+ ||+||||||| | Sbjct 15 GEVEWTGAWSDGSSEWNGVDPYMREQLRVK#M-EDGEFWMSFRDFMREFTRLEICNLTPD 72 |
| Bos grunniens | Query 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTAD 351 |+||| | |+| +|+ || + + | |# ||||||||++||+ |+++||||||| | Sbjct 1 GEVEWTGQWNDNCPNWNTVDPEVRETLTRQ#-HEDGEFWMSFNDFLRHYSRLEICNLTPD 58 |
| Drosophila melanogaster | Query 294 QVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 + |||| ||| +| ++ +++|| + # |||||||+ ||+ || ++|||||+ |+ Sbjct 309 EAEWNGPWSDSSPEWRYIPEEQKAEIGLT#FDRDGEFWMSFQDFLNHFDRVEICNLSPDS 367 |
| Schistosoma japonicum | Query 296 EWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNL 348 || |+||| |+|| + +++ +| # +|||||||| ||| +| |||||+| Sbjct 368 EWKGAWSDKSKEWSLISPEQRQQLGLT#FDDDGEFWMSYQDFVSNFEKLEICHL 420 |
| Anopheles gambiae | Query 294 QVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 + |||| ||| +| ++ ++| | # |||||||| || +| ++|||||+ |+ Sbjct 15 EAEWNGPWSDKSPEWRYIPDEQKQELGLN#FDHDGEFWMSYRDFTRYFDRMEICNLSPDS 73 |
| Tribolium castaneum | Query 296 EWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||||+||| +| ++ +| | # |||||||+ || || ++||||| |+ Sbjct 701 EWNGAWSDHSPEWHYISDSDKEELGLN#FDADGEFWMSFKDFQQHFNRIEICNLNPDS 757 |
| Anopheles gambiae str. PEST | Query 294 QVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 + |||| ||| +| ++ ++| | # |||||||| || +| ++|||||+ |+ Sbjct 15 EAEWNGPWSDKSPEWRYIPDEQKQELGLN#FDHDGEFWMSYRDFTRYFDRMEICNLSPDS 73 |
| Aedes aegypti | Query 295 VEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTAD 351 +||||+||| ++| + | ++ +| #+ |||||| ++||+ +| ++|||||+ | Sbjct 307 IEWNGAWSDRSQEWQAIPKAQRKQLGLT#IDNDGEFWMDFEDFLRYFDRVEICNLSPD 363 |
| Homarus americanus | Query 294 QVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTAD 351 + || ||||| +|+ + +|| ||+ # +|||||||+ || +|| +|||++| + Sbjct 334 EAEWKGSWSDKSPEWNSITPEEKQRLKLN#FEDDGEFWMSFQDFASNFTTVEICDVTPE 391 |
| Gecarcinus lateralis | Query 294 QVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTAD 351 + || ||||| +|+ | |+ || # +|||||||| ||+ +|| +|||++ | Sbjct 334 ETEWKGSWSDKSPEWNAVPPGERQRLGLT#FNDDGEFWMSYQDFLKNFTTVEICDVNPD 391 |
| Drosophila pseudoobscura | Query 296 EWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 ||+| ||| +| |+ + | + # |||||||+ ||+ || ++||||| |+ Sbjct 511 EWSGPWSDSSPEWRFIPEHVKEEIGLN#FDRDGEFWMSFQDFLNHFDRVEICNLNPDS 567 |
| Schistosoma haematobium | Query 296 EWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNL 348 || |+| || | + + || + # | ||||||||+||| ||++|+|+| Sbjct 344 EWKGAWCDGSPQWREISEQEKKNINLS#FTADGEFWMSYEDFVTCFTRVEVCHL 396 |
* References
[PubMed ID: 9733588] Ma H, Shih M, Hata I, Fukiage C, Azuma M, Shearer TR, Protein for Lp82 calpain is expressed and enzymatically active in young rat lens. Exp Eye Res. 1998 Aug;67(2):221-9.