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XSB2336 : Chain A, Close Packing Of An Oligomeric Eye Lens Beta-Crystallin Induces Loss Of Symmetry And Ordering Of Sequence Extensions

[ CaMP Format ]

This entry is computationally expanded from SB0082

* Basic Information

OrganismBos taurus (cattle)
Protein NamesBeta-crystallin B2; Beta-B2 crystallin; Beta-crystallin Bp
Gene NamesCRYBB2
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
1BLB_A N/A N/A CRBB2_BOVIN N/A N/A N/A bta:287011

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 204 aa

Average Mass: 23.167 kDa

Monoisotopic Mass: 23.152 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
--- cleavage 7 ---
Crystall 1. 1799163.18.4e-46
Crystall 2. 107189167.83.2e-47

3. Sequence Information

Fasta Sequence: XSB2336.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1BLB (X-ray; 330 A; A/B/C/D=2-204), 2BB2 (X-ray; 210 A; A=15-195)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] ASDHQTQ7-AGKPQPLNPK

Gln7 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
---Ala1Ser2Asp3His4Gln5Thr6Gln7
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala8Gly9Lys10Pro11Gln12Pro13Leu14Asn15Pro16Lys17

Sequence conservation (by blast)

* References

[PubMed ID: 7108959] Slingsby C, Miller LR, Berbers GA, Preliminary x-ray crystallographic study of the principal subunit of the lens structural protein, bovine beta-crystallin. J Mol Biol. 1982 May 5;157(1):191-4.

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