XSB2366 : hUp84 [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0104
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | hUp84 |
| Gene Names | CAPN3 |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| BAD16649 | N/A | N/A | Q762C8_HUMAN | N/A | N/A | N/A | hsa: |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 728 aa
Average Mass: 84.084 kDa
Monoisotopic Mass: 84.030 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Peptidase_C2 1. | 1 | 330 | 819.9 | 1.6e-243 |
| --- cleavage 277 (inside Peptidase_C2 1..330) --- | ||||
| --- cleavage 303 (inside Peptidase_C2 1..330) --- | ||||
| Calpain_III 1. | 341 | 495 | 367.3 | 2.8e-107 |
| Osmo_CC 1. | 550 | 595 | 2.9 | 6 |
| efhand 1. | 603 | 631 | 27.9 | 4e-05 |
| efhand 2. | 633 | 661 | 26.7 | 9.3e-05 |
| efhand 3. | 698 | 725 | 9.1 | 2.2 |
3. Sequence Information
Fasta Sequence: XSB2366.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
2 [sites]
Cleavage sites (±10aa)
[Site 1] RLRNPWGQVE277-WNGSWSDRWK
Glu277 
Trp
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Arg268 | Leu269 | Arg270 | Asn271 | Pro272 | Trp273 | Gly274 | Gln275 | Val276 | Glu277 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Trp278 | Asn279 | Gly280 | Ser281 | Trp282 | Ser283 | Asp284 | Arg285 | Trp286 | Lys287 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| AYSVTELDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTED |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 133.00 | 47 | hUp84 |
| 2 | Pan troglodytes | 127.00 | 12 | PREDICTED: similar to Calpain-3 (Calpain L3) (Calp |
| 3 | Macaca mulatta | 124.00 | 4 | PREDICTED: calpain 3 |
| 4 | Macaca fascicularis | 124.00 | 1 | CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (C |
| 5 | Mus musculus | 121.00 | 33 | AF127766_1 calpain 3; calcium activated neutral pr |
| 6 | N/A | 121.00 | 18 | 1 |
| 7 | Rattus norvegicus | 121.00 | 15 | calpain isoform Lp85 |
| 8 | Sus scrofa | 121.00 | 4 | lens-specific calpain Lp82 |
| 9 | Oryctolagus cuniculus | 121.00 | 1 | calpain 3, (p94) |
| 10 | Bos taurus | 119.00 | 11 | lens-specific calpain Lp82 |
| 11 | Ovis aries | 119.00 | 2 | skeletal muscle-specific calpain |
| 12 | Canis familiaris | 118.00 | 24 | PREDICTED: similar to calpain 3 isoform c isoform |
| 13 | Monodelphis domestica | 102.00 | 7 | PREDICTED: similar to ZP1-related protein |
| 14 | Gallus gallus | 98.60 | 7 | calpain 3, (p94) |
| 15 | Oncorhynchus mykiss | 84.70 | 4 | gill-specific calpain |
| 16 | Danio rerio | 81.30 | 25 | hypothetical protein LOC445107 |
| 17 | Xenopus laevis | 79.70 | 12 | MGC83034 protein |
| 18 | Tetraodon nigroviridis | 79.30 | 6 | unnamed protein product |
| 19 | Xenopus tropicalis | 71.20 | 6 | calpain 8 (nCL-2) |
| 20 | Coturnix coturnix | 69.30 | 1 | quail calpain |
| 21 | Caenorhabditis elegans | 68.60 | 3 | CaLPain family member (clp-6) |
| 22 | Pongo pygmaeus | 67.40 | 1 | CAN1_PONPY Calpain-1 catalytic subunit (Calpain-1 |
| 23 | catalytic | 67.00 | 1 | Calpain 2, large |
| 24 | Strongylocentrotus purpuratus | 67.00 | 1 | PREDICTED: similar to calpain B isoform 2 |
| 25 | synthetic construct | 67.00 | 1 | Homo sapiens calpain 1, (mu/I) large subunit |
| 26 | Stizostedion vitreum vitreum | 66.60 | 1 | putative calpain-like protein |
| 27 | Bos grunniens | 64.30 | 1 | micromolar calcium-activated neutral protease 1 la |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 |
| Pan troglodytes | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |||| |||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 287 AYSVTGLDEVLFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 346 |
| Macaca mulatta | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |||| |||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 335 AYSVTGLDEVLFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 394 |
| Macaca fascicularis | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |||| |||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 335 AYSVTGLDEVLFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 394 |
| Mus musculus | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |+| |||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 287 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 346 |
| N/A | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |+| |||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 335 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 394 |
| Rattus norvegicus | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |+| |||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |
| Sus scrofa | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |+| |||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 267 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDSWKDWSFVDKDEKARLQHQVTED 326 |
| Oryctolagus cuniculus | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |+| |||||||||||||||||||#||||||| |||||||||||||||||||||| Sbjct 267 AYSVTGLEETLFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKDEKARLQHQVTED 326 |
| Bos taurus | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |+| +||||||||||||||||||#||||||| |||||+|||||||||||||||| Sbjct 267 AYSVTGLEEALYKGEKVKLVRLRNPWGQVE#WNGSWSDSWKDWSYVDKDEKARLQHQVTED 326 |
| Ovis aries | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |+| +||||||||||||||||||#||||||| |||||+|||||||||||||||| Sbjct 336 AYSVTGLEEALYKGEKVKLVRLRNPWGQVE#WNGSWSDSWKDWSYVDKDEKARLQHQVTED 395 |
| Canis familiaris | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| |+| |||||||||||||||||||#||||||| ||||||||| |||||||||||| Sbjct 287 AYSVTGLEEALFKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWSFVDKAEKARLQHQVTED 346 |
| Monodelphis domestica | Query 259 FKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 |||||||||||||||||||#||||||| |||| +||+||+||||||||| Sbjct 317 FKGEKVKLVRLRNPWGQVE#WNGSWSDGWKDWVLIDKEEKSRLQHQVTED 365 |
| Gallus gallus | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| ++| +||||++||||||||||||#||| |||+ ++|+|+|++|| ||||++ || Sbjct 328 AYSVTAVEETTYKGEKMRLVRLRNPWGQVE#WNGPWSDKSEEWNFIDEEEKIRLQHKIAED 387 |
| Oncorhynchus mykiss | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 |||+| |+|| ++|+||||+|+||||||||#|||+||| ++|+ +| || |+ +| Sbjct 241 AYSITGLEEVNYRGKKVKLIRIRNPWGQVE#WNGAWSDESREWNVIDSSEKKRILQNSMDD 300 |
| Danio rerio | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| ++|| ++| ||+|+|+||||||||#||| ||| ++|+ +| || || +| Sbjct 253 AYSVTGVEEVNYRGAKVQLIRVRNPWGQVE#WNGPWSDNSREWTVIDSSEKKRLLQNSLDD 312 |
| Xenopus laevis | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 |||+| | | |+|+||||+|+||||||||#|||+||| +|+ + || || +| Sbjct 255 AYSITATDVVNFQGQKVKLIRIRNPWGQVE#WNGAWSDNSSEWNIIGAAEKNRLSQASLDD 314 |
| Tetraodon nigroviridis | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQ 303 ||||| |+| ++|| |+|||+||||||||#|||+||| +| +| |++ || ++ Sbjct 269 AYSVTGADQVEYRGEAVQLVRIRNPWGQVE#WNGAWSDDSSEWRYVSSDDRERLTNR 324 |
| Xenopus tropicalis | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQ 303 ||||| +|| ++| + ||+|+|||||+||#| | ||| +|+++| || | | Sbjct 264 AYSVTGAEEVLYRGRQEKLIRVRNPWGEVE#WTGPWSDTAPEWNYIDPKVKAALDKQ 319 |
| Coturnix coturnix | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTE 306 ||||| +| ++|++ +|+|+||||||||#| |+||| +| +| ++ || ++ + Sbjct 266 AYSVTAFKDVNYRGQQEQLIRIRNPWGQVE#WTGAWSDGSPEWDNIDPSDREELQQKMED 324 |
| Caenorhabditis elegans | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQVTED 307 ||||| + | ||| |+|+||||| |#||| |||+ | ||++++ +++ ++ || Sbjct 370 AYSVTGVHTVETDKEKVALLRIRNPWGDTE#WNGDWSDKSSLWEQVDQEQREKMEFRIKED 429 |
| Pongo pygmaeus | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQ 301 ||||| +| ++|+ | |+|+|||||+||#| |+||| +|+ || |+ +|+ Sbjct 273 AYSVTGAKQVNYRGQMVSLIRMRNPWGEVE#WTGAWSDSSSEWNNVDPYERDQLR 326 |
| catalytic | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARL 300 ||||| +|| | ||+|+|||||+||#| | |+| |+ +| +|+ || Sbjct 292 AYSVTGAEEVESNGSLQKLIRIRNPWGEVE#WTGRWNDNCPSWNTIDPEERERL 344 |
| Strongylocentrotus purpuratus | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARL 300 ||++|++ +| || |+|+|+||||| ||#||| ||| ++| +++ |+ | Sbjct 236 AYTITDVKKVNVKGRDVRLIRIRNPWGAVE#WNGRWSDNAREWDDINQRERKNL 288 |
| synthetic construct | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQ 301 ||||| +| ++|+ | |+|+|||||+||#| |+||| +|+ || |+ +|+ Sbjct 273 AYSVTGAKQVNYRGQVVSLIRMRNPWGEVE#WTGAWSDSSSEWNNVDPYERDQLR 326 |
| Stizostedion vitreum vitreum | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQHQ 303 ||||| +| +| ||+|+||||||||#| |+||| | + +++ || |+ Sbjct 264 AYSVTGTAQVEHQGGTEKLIRIRNPWGQVE#WTGAWSDNSMQWRRISSEDRERLSHR 319 |
| Bos grunniens | Query 248 AYSVTELDEVPFKGEKVKLVRLRNPWGQVE#WNGSWSDRWKDWSFVDKDEKARLQ 301 ||||| +| ++|+ | |+|+|||||+||#| |+||| +|+ || + +|+ Sbjct 237 AYSVTGAKQVNYQGQMVNLIRMRNPWGEVE#WTGAWSDGSSEWNGVDPYMREQLR 290 |
[Site 2] KDEKARLQHQ303-VTEDGEFWMS
Gln303 Val
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Lys294 | Asp295 | Glu296 | Lys297 | Ala298 | Arg299 | Leu300 | Gln301 | His302 | Gln303 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Val304 | Thr305 | Glu306 | Asp307 | Gly308 | Glu309 | Phe310 | Trp311 | Met312 | Ser313 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| GQVEWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADA |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 137.00 | 38 | calpain 3 isoform f |
| 2 | Pan troglodytes | 137.00 | 11 | PREDICTED: similar to Calpain-3 (Calpain L3) (Calp |
| 3 | N/A | 134.00 | 20 | - |
| 4 | Macaca mulatta | 134.00 | 4 | PREDICTED: calpain 3 |
| 5 | Sus scrofa | 134.00 | 4 | lens-specific calpain Lp82 |
| 6 | Macaca fascicularis | 134.00 | 1 | CAN3_MACFA Calpain-3 (Calpain L3) (Calpain p94) (C |
| 7 | Mus musculus | 133.00 | 33 | calpain 3 |
| 8 | Rattus norvegicus | 133.00 | 16 | calpain isoform Lp85 |
| 9 | Bos taurus | 132.00 | 10 | lens-specific calpain Lp82 |
| 10 | Ovis aries | 132.00 | 2 | skeletal muscle-specific calpain |
| 11 | Oryctolagus cuniculus | 131.00 | 1 | calpain 3, (p94) |
| 12 | Canis familiaris | 130.00 | 22 | PREDICTED: similar to calpain 3 isoform c isoform |
| 13 | Monodelphis domestica | 123.00 | 5 | PREDICTED: similar to ZP1-related protein |
| 14 | Gallus gallus | 102.00 | 7 | calpain 3, (p94) |
| 15 | Danio rerio | 90.50 | 21 | calpain 3, (p94) |
| 16 | Tetraodon nigroviridis | 86.30 | 5 | unnamed protein product |
| 17 | Oncorhynchus mykiss | 85.10 | 3 | calpain 1 catalytic subunit |
| 18 | Xenopus laevis | 84.70 | 9 | MGC83034 protein |
| 19 | Stizostedion vitreum vitreum | 80.50 | 1 | putative calpain-like protein |
| 20 | Xenopus tropicalis | 78.20 | 5 | CAPN2 protein |
| 21 | Coturnix coturnix | 77.80 | 1 | quail calpain |
| 22 | Caenorhabditis elegans | 77.00 | 4 | CaLPain family member (clp-4) |
| 23 | catalytic | 77.00 | 1 | Calpain 2, large |
| 24 | Pongo pygmaeus | 77.00 | 1 | CAN1_PONPY Calpain-1 catalytic subunit (Calpain-1 |
| 25 | synthetic construct | 77.00 | 1 | Homo sapiens calpain 1, (mu/I) large subunit |
| 26 | Bos grunniens | 74.70 | 2 | calpain 2 |
| 27 | Drosophila melanogaster | 74.30 | 7 | CAA55297.1 |
| 28 | Caenorhabditis briggsae | 74.30 | 2 | Hypothetical protein CBG15134 |
| 29 | Aedes aegypti | 73.60 | 3 | calpain, putative |
| 30 | Bos taurus x Bos indicus | 72.80 | 1 | micromolar calcium activated neutral protease 1 |
| 31 | Schistosoma japonicum | 71.60 | 1 | SJCHGC01809 protein |
| 32 | Anopheles gambiae | 71.60 | 1 | calpain |
| 33 | Anopheles gambiae str. PEST | 71.60 | 1 | ENSANGP00000032073 |
| 34 | Homarus americanus | 71.20 | 1 | muscle-specific calpain |
| 35 | Tribolium castaneum | 70.90 | 1 | PREDICTED: similar to CG8107-PA |
| 36 | Gecarcinus lateralis | 70.50 | 2 | muscle-specific calpain |
| 37 | Drosophila pseudoobscura | 68.20 | 1 | GA20829-PA |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 |
| Pan troglodytes | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 |
| N/A | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| ||||||||||||||||||#|||||||||||+|||||||||||||||||| Sbjct 84 GQVEWNGSWSDSWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFIYHFTKLEICNLTADA 143 |
| Macaca mulatta | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| ||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 361 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 420 |
| Sus scrofa | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| ||||||||||||||||||#|||||||||||+|||||||||||||||||| Sbjct 293 GQVEWNGSWSDSWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFIYHFTKLEICNLTADA 352 |
| Macaca fascicularis | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| ||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 361 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 420 |
| Mus musculus | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| ||||||||||||||||||#|||||||||||+||+||||||||||||||| Sbjct 313 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 372 |
| Rattus norvegicus | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| ||||||||||||||||||#|||||||||||+||+||||||||||||||| Sbjct 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVYHFTKLEICNLTADA 352 |
| Bos taurus | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| |||||+||||||||||||#|||||||||||+|||||||||||||||||| Sbjct 293 GQVEWNGSWSDSWKDWSYVDKDEKARLQHQ#VTEDGEFWMSYDDFIYHFTKLEICNLTADA 352 |
| Ovis aries | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| |||||+||||||||||||#|||||||||||+|||||||||||||||||| Sbjct 362 GQVEWNGSWSDSWKDWSYVDKDEKARLQHQ#VTEDGEFWMSYDDFIYHFTKLEICNLTADA 421 |
| Oryctolagus cuniculus | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| ||||||||||||||||||#|||||||||||+||++|||||||||||||| Sbjct 293 GQVEWNGSWSDGWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYDDFVFHFTKLEICNLTADA 352 |
| Canis familiaris | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| ||||||||| ||||||||#|||||||||||+|||||||||||||||||| Sbjct 313 GQVEWNGSWSDGWKDWSFVDKAEKARLQHQ#VTEDGEFWMSYDDFIYHFTKLEICNLTADA 372 |
| Monodelphis domestica | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||||||| |||| +||+||+|||||#||||||||||||||+|+||||||||||||| Sbjct 332 GQVEWNGSWSDGWKDWVLIDKEEKSRLQHQ#VTEDGEFWMSYEDFMYNFTKLEICNLTADA 391 |
| Gallus gallus | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTAD 332 ||||||| |||+ ++|+|+|++|| ||||+#+ ||||||+| |||+ ||||||||||| | Sbjct 354 GQVEWNGPWSDKSEEWNFIDEEEKIRLQHK#IAEDGEFWISLEDFMRHFTKLEICNLTPD 412 |
| Danio rerio | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||||| ||| |+| + | || +|| |# ||||||||+||| ++||+|||||| || Sbjct 297 GQVEWNGPWSDNSKEWESLSKAEKEKLQQQ#NAEDGEFWMSFEDFKKNYTKIEICNLTPDA 356 |
| Tetraodon nigroviridis | Query 274 GQVEWNGSWSDR----------WKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTK 323 ||||||| |||+ |+|| + | || +| ||# ||||||||+||| ++|| Sbjct 297 GQVEWNGPWSDKNRPFRLLRNSSKEWSTLSKAEKEKLHHQ#SAEDGEFWMSFEDFKKNYTK 356 Query 324 LEICNLTADA 333 +|||||| || Sbjct 357 IEICNLTPDA 366 |
| Oncorhynchus mykiss | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 |++|| |+||| ++| ||+ + |||++# +||||||||+ ||+ ||+|||||||||| Sbjct 294 GEIEWTGAWSDNSREWESVDRSVRGRLQNR#-SEDGEFWMSFSDFLREFTRLEICNLTADA 352 |
| Xenopus laevis | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 |||||||+||| +|+ + || || # +|||||| +||| || |||||||| || Sbjct 281 GQVEWNGAWSDNSSEWNIIGAAEKNRLSQA#SLDDGEFWMDFEDFKRHFDKLEICNLTPDA 340 |
| Stizostedion vitreum vitreum | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||| |+||| | + +++ || |+# +||||||||+ ||+ |+ +||||||| || Sbjct 290 GQVEWTGAWSDNSMQWRRISSEDRERLSHR#-SEDGEFWMSFADFLRHYDRLEICNLTPDA 348 |
| Xenopus tropicalis | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||| |+||| +|+ || |+ || +#+ ||||||||+++|+ |++||||||| || Sbjct 292 GQVEWTGAWSDNSSEWNEVDPSEQEDLQLK#M-EDGEFWMSFQEFLRQFSRLEICNLTPDA 350 |
| Coturnix coturnix | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||| |+||| +| +| ++ || +#+ ||||||||+ ||+ |++||||||| || Sbjct 292 GQVEWTGAWSDGSPEWDNIDPSDREELQQK#M-EDGEFWMSFRDFMREFSRLEICNLTPDA 350 |
| Caenorhabditis elegans | Query 277 EWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTAD 332 ||||+||| +|| +|+ | ++ |# |||||||+||| +||++|+|||||+ Sbjct 483 EWNGAWSDGSSEWSKIDEATKKQIDVQ#FARDGEFWMSFEDFFSNFTQMEVCNLTAE 538 |
| catalytic | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTAD 332 |+||| | |+| |+ +| +|+ || +# ||||||||+ ||+ |+++||||||| | Sbjct 318 GEVEWTGRWNDNCPSWNTIDPEERERLTRR#-HEDGEFWMSFSDFLRHYSRLEICNLTPD 375 |
| Pongo pygmaeus | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 |+||| |+||| +|+ || |+ +|+ +#+ ||||||||+ ||+ ||+||||||| || Sbjct 299 GEVEWTGAWSDSSSEWNNVDPYERDQLRVK#M-EDGEFWMSFRDFMREFTRLEICNLTPDA 357 |
| synthetic construct | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 |+||| |+||| +|+ || |+ +|+ +#+ ||||||||+ ||+ ||+||||||| || Sbjct 299 GEVEWTGAWSDSSSEWNNVDPYERDQLRVK#M-EDGEFWMSFRDFMREFTRLEICNLTPDA 357 |
| Bos grunniens | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTAD 332 |+||| | |+| +|+ || + + | |# ||||||||+ ||+ |+++||||||| | Sbjct 1 GEVEWTGQWNDNCPNWNTVDPEVRETLTRQ#-HEDGEFWMSFNDFLRHYSRLEICNLTPD 58 |
| Drosophila melanogaster | Query 275 QVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 + |||| ||| +| ++ +++|| + # |||||||++||+ || ++|||||+ |+ Sbjct 309 EAEWNGPWSDSSPEWRYIPEEQKAEIGLT#FDRDGEFWMSFQDFLNHFDRVEICNLSPDS 367 |
| Caenorhabditis briggsae | Query 276 VEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTAD 332 +||||+||| +|| +|+ | ++ |# ||||||+++|| +||++|+|||||+ Sbjct 449 LEWNGAWSDGSMEWSKIDEATKKQIDVQ#FARDGEFWMNFDDFFANFTQMELCNLTAE 505 |
| Aedes aegypti | Query 276 VEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTAD 332 +||||+|||| ++| + | ++ +| #+ |||||| +|||+ +| ++|||||+ | Sbjct 307 IEWNGAWSDRSQEWQAIPKAQRKQLGLT#IDNDGEFWMDFEDFLRYFDRVEICNLSPD 363 |
| Bos taurus x Bos indicus | Query 274 GQVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTAD 332 |+||| |+||| +|+ || + +|+ +#+ ||||||||+ ||+ ||+||||||| | Sbjct 15 GEVEWTGAWSDGSSEWNGVDPYMREQLRVK#M-EDGEFWMSFRDFMREFTRLEICNLTPD 72 |
| Schistosoma japonicum | Query 277 EWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNL 329 || |+|||+ |+|| + +++ +| # +||||||||+||+ +| |||||+| Sbjct 368 EWKGAWSDKSKEWSLISPEQRQQLGLT#FDDDGEFWMSYQDFVSNFEKLEICHL 420 |
| Anopheles gambiae | Query 275 QVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 + |||| |||+ +| ++ ++| | # |||||||| || +| ++|||||+ |+ Sbjct 15 EAEWNGPWSDKSPEWRYIPDEQKQELGLN#FDHDGEFWMSYRDFTRYFDRMEICNLSPDS 73 |
| Anopheles gambiae str. PEST | Query 275 QVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 + |||| |||+ +| ++ ++| | # |||||||| || +| ++|||||+ |+ Sbjct 15 EAEWNGPWSDKSPEWRYIPDEQKQELGLN#FDHDGEFWMSYRDFTRYFDRMEICNLSPDS 73 |
| Homarus americanus | Query 275 QVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTAD 332 + || |||||+ +|+ + +|| ||+ # +|||||||++|| +|| +|||++| + Sbjct 334 EAEWKGSWSDKSPEWNSITPEEKQRLKLN#FEDDGEFWMSFQDFASNFTTVEICDVTPE 391 |
| Tribolium castaneum | Query 277 EWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||||+||| +| ++ +| | # |||||||++|| || ++||||| |+ Sbjct 701 EWNGAWSDHSPEWHYISDSDKEELGLN#FDADGEFWMSFKDFQQHFNRIEICNLNPDS 757 |
| Gecarcinus lateralis | Query 275 QVEWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTAD 332 + || |||||+ +|+ | |+ || # +||||||||+||+ +|| +|||++ | Sbjct 334 ETEWKGSWSDKSPEWNAVPPGERQRLGLT#FNDDGEFWMSYQDFLKNFTTVEICDVNPD 391 |
| Drosophila pseudoobscura | Query 277 EWNGSWSDRWKDWSFVDKDEKARLQHQ#VTEDGEFWMSYEDFIYHFTKLEICNLTADA 333 ||+| ||| +| |+ + | + # |||||||++||+ || ++||||| |+ Sbjct 511 EWSGPWSDSSPEWRFIPEHVKEEIGLN#FDRDGEFWMSFQDFLNHFDRVEICNLNPDS 567 |
* References
[PubMed ID: 14675785] Kawabata Y, Hata S, Ono Y, Ito Y, Suzuki K, Abe K, Sorimachi H, Newly identified exons encoding novel variants of p94/calpain 3 are expressed ubiquitously and overlap the alpha-glucosidase C gene. FEBS Lett. 2003 Dec 18;555(3):623-30.