CaMPDB :: Substrate

XSB2372 : unnamed protein product [Homo sapiens]

This entry is computationally expanded from SB0057

* Basic Information

Organism	Homo sapiens (human)
Protein Names	Microtubule-associated protein
Gene Names	Not available
Gene Locus	Not available
GO Function	Not available

Entrez Protein	Entrez Nucleotide	Entrez Gene	UniProt	OMIM	HGNC	HPRD	KEGG
BAF84135	N/A	N/A	A8K5Y1_HUMAN	N/A	N/A	N/A	hsa:

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 471 aa

Average Mass: 49.568 kDa

Monoisotopic Mass: 49.539 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain name	begin	end	score	e-value
RII_binding_1 1.	86	103	19.2	0.017
--- cleavage 99 (inside RII_binding_1 86..103) ---
Drf_FH1 1.	135	298	-37.3	2.9
Tubulin-binding 1.	304	335	64.3	4.4e-16
Tubulin-binding 2.	336	366	66.0	1.4e-16
Tubulin-binding 3.	367	398	55.1	2.6e-13

3. Sequence Information

Fasta Sequence: XSB2372.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] VSARIVQVVT⁹⁹-AEAVAVLKGE

Thr⁹⁹ Ala

P10	P9	P8	P7	P6	P5	P4	P3	P2	P1

Val⁹⁰	Ser⁹¹	Ala⁹²	Arg⁹³	Ile⁹⁴	Val⁹⁵	Gln⁹⁶	Val⁹⁷	Val⁹⁸	Thr⁹⁹

P1'	P2'	P3'	P4'	P5'	P6'	P7'	P8'	P9'	P10'
Ala¹⁰⁰	Glu¹⁰¹	Ala¹⁰²	Val¹⁰³	Ala¹⁰⁴	Val¹⁰⁵	Leu¹⁰⁶	Lys¹⁰⁷	Gly¹⁰⁸	Glu¹⁰⁹

Sequence conservation (by blast) Sequence conservation (by blast)

Reference peptide (cleaved bond±30 residues)
TKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKGAQHKDQTAALPLAAEE

Summary

#	organism	max score	hits	top seq
1	Homo sapiens	112.00	11	microtubule-associated protein 2 isoform 2
2	N/A	112.00	5	M
3	Pan troglodytes	112.00	4	PREDICTED: microtubule-associated protein 2 isofor
4	Macaca mulatta	112.00	4	PREDICTED: similar to Microtubule-associated prote
5	Macaca fascicularis	112.00	1	unnamed protein product
6	Rattus norvegicus	110.00	6	CAA35667.1
7	Mus musculus	110.00	5	microtubule-associated protein 2 isoform 2
8	Canis familiaris	110.00	5	PREDICTED: similar to microtubule-associated prote
9	Rattus rattus	110.00	1	microtubule-associated protein 2
10	Bos taurus	102.00	2	Unknown (protein for IMAGE:8408137)
11	Gallus gallus	98.60	1	PREDICTED: similar to microtubule-associated prote
12	Monodelphis domestica	98.20	2	PREDICTED: similar to microtubule-associated prote
13	Xenopus tropicalis	83.60	1	microtubule-associated protein 2
14	Danio rerio	64.30	1	hypothetical protein LOC450004
15	Burkholderia dolosa AUO158	32.70	1	hypothetical protein BdolA_01003230
16	Burkholderia ambifaria MC40-6	32.70	1	hypothetical protein BamMC406DRAFT_0880

Top-ranked sequences

organism	matching
Homo sapiens	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQTAALPLAAEE 129
N/A	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQTAALPLAAEE 129
Pan troglodytes	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQTAALPLAAEE 129
Macaca mulatta	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQTAALPLAAEE 129
Macaca fascicularis	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQTAALPLAAEE 129
Rattus norvegicus	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\| \|\|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQPAALPLAAEE 129
Mus musculus	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\| \|\|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQPAALPLAAEE 129
Canis familiaris	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\| \|\|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQPAALPLAAEE 129
Rattus rattus	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\| \|\|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQPAALPLAAEE 129
Bos taurus	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\| \|\|\| \|\|\|\|\|\|\|\| Sbjct 70 TKENGINGELTSTDRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQPKDQPPALPLAAEE 129
Gallus gallus	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 +\|\|\|\|\|\|\|\|\|++ \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\| \|\|+\| \|\| Sbjct 70 SKENGINGELSAGDRETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQHKDQPGPLPIAVEE 129
Monodelphis domestica	Query 70 TKENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|\|\|\|+\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\| \|\| \|\|\| \|\|+\| \|\| Sbjct 70 TKENGINGELTTAERETAEEVSARIVQVVT#AEAVAVLKGEQEKEAQPKDQPTGLPIAVEE 129
Xenopus tropicalis	Query 71 KENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAAEE 129 \|\|\|\|\|\|\|\|+ \|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|+\|\|\|\|\|+\|\|\|\|\| \|\| + \|\|\|\| \|+ Sbjct 71 KENGINGEMPSADSETAEEVSARIVQVVT#ADAVAVLRGEQEKEAQLRGPPGDLPLAVED 129
Danio rerio	Query 71 KENGINGELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALP 124 \|\|\|\| \|\|+\|\|\| \|\|\|+\|\|\|\|\|\|\| \|\|#\|\|\|\|\|\|\|\|\|\|\|\| \| + \|\| Sbjct 51 KENGFNGDLTSGHAVTAEQVSARIVQEVT#AEAVAVLKGEQE---LHPETAVRLP 101
Burkholderia dolosa AUO158	Query 77 GELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAA 127 \|+\|+ \|+ \| ++ \|+\|#\| ++\| \|\|+\| \|\| ++ \|+\|+ \| \| Sbjct 219 GKLSRIARDDAHPLTQHARDVLT#AMSIAENKGKQRNGALYQSVTSAIGLTA 269
Burkholderia ambifaria MC40-6	Query 77 GELTSADRETAEEVSARIVQVVT#AEAVAVLKGEQEKGAQHKDQTAALPLAA 127 \|+\|+ \|+ \| ++ \|+\|#\| ++\| \|\|+\| \|\| ++ \|+\|+ \| \| Sbjct 236 GKLSRIARDDAHPLTQHARDVLT#AMSIAENKGKQRNGALYQSVTSAIGLTA 286

* References

None.