XSB2598 : insulin-like growth factor binding protein 3 isoform b precursor [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0098
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | Insulin-like growth factor binding protein 3 isoform b; insulin-like growth factor binding protein 3 isoform b precursor |
| Gene Names | Not available |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 263 aa
Average Mass: 28.980 kDa
Monoisotopic Mass: 28.961 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| IGFBP 1. | 12 | 71 | 99.8 | 9.1e-27 |
| --- cleavage 141 --- |
| Thyroglobulin_1 1. | 185 | 257 | 121.6 | 2.6e-33 |
3. Sequence Information
Fasta Sequence: XSB2598.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] VSDPKFHPLH141-SKIIIIKKGH
His141 
Ser
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Val132 | Ser133 | Asp134 | Pro135 | Lys136 | Phe137 | His138 | Pro139 | Leu140 | His141 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ser142 | Lys143 | Ile144 | Ile145 | Ile146 | Ile147 | Lys148 | Lys149 | Gly150 | His151 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
SEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQN
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Homo sapiens |
97.80 |
7 |
insulin-like growth factor binding protein 3, isof |
| 2 |
synthetic construct |
97.80 |
3 |
insulin-like growth factor binding protein 3 |
| 3 |
Macaca mulatta |
96.70 |
1 |
PREDICTED: similar to insulin-like growth factor b |
| 4 |
Mus musculus |
83.60 |
6 |
PREDICTED: similar to Insulin-like growth factor-b |
| 5 |
Sus scrofa |
81.30 |
3 |
insulin-like growth factor-binding protein 3 |
| 6 |
N/A |
81.30 |
3 |
- |
| 7 |
Bos taurus |
81.30 |
1 |
insulin-like growth factor binding protein 3 |
| 8 |
Equus caballus |
80.50 |
1 |
insulin-like growth factor binding protein-3 |
| 9 |
Rattus norvegicus |
80.10 |
1 |
insulin-like growth factor binding protein 3 |
| 10 |
Canis familiaris |
77.00 |
1 |
PREDICTED: similar to Insulin-like growth factor b |
| 11 |
Capra hircus |
73.60 |
2 |
insulin-like growth factor binding protein-3 |
| 12 |
Ovis aries |
71.60 |
1 |
AF327651_1 insulin-like growth factor binding prot |
Top-ranked sequences
| organism | matching |
|---|
| Homo sapiens |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
||||| |||||||||||||#||||||||||||||||||||||||||||||
Sbjct 102 SEEDRSAGSVESPSVSSTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 161
|
| synthetic construct |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
||||| |||||||||||||#||||||||||||||||||||||||||||||
Sbjct 140 SEEDRSAGSVESPSVSSTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 199
|
| Macaca mulatta |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
||||| |||||||||||+|#||||||||||||||||||||||||||||||
Sbjct 140 SEEDRSAGSVESPSVSSTHRVSDPKFHPVH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 199
|
| Mus musculus |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
|||+ ||||+| ||||||#+|+ +||||||+||||||||||||||||||
Sbjct 117 SEEEHNAGSVESQVVPSTHRVTDSKFHPLH#AKMDVIKKGHARDSQRYKVDYESQSTDTQN 176
|
| Sus scrofa |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
||||| |||| | | | +|#+|+ +|||||||||||||||||||||||||
Sbjct 142 SEEDRSVDSMENQALPSTHRVPDSKLHSIH#TKMDVIKKGHAKDSQRYKVDYESQSTDTQN 201
|
| N/A |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
|||| |||| ||||+|#+|+ +|||||||||||||||||||||||||
Sbjct 140 SEEDHSMGSTENQAGPSTHRVPVSKFHPIH#TKMDVIKKGHAKDSQRYKVDYESQSTDTQN 199
|
| Bos taurus |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
|||| |||| ||||+|#+|+ +|||||||||||||||||||||||||
Sbjct 140 SEEDHSMGSTENQAGPSTHRVPVSKFHPIH#TKMDVIKKGHAKDSQRYKVDYESQSTDTQN 199
|
| Equus caballus |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
|||| || + ||||| +|#+|+ +|||||||||||||||||||||||||
Sbjct 8 SEEDHSAGSVDNQAVPSTHCMPDPKFHTIH#TKMDVIKKGHAKDSQRYKVDYESQSTDTQN 67
|
| Rattus norvegicus |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
|||| ||||+| ||||||#||+ +| || |+||||||||||||||||||
Sbjct 141 SEEDHNAGSVESQVVPSTHRVTDSKFHPLH#SKMEVIIKGQARDSQRYKVDYESQSTDTQN 200
|
| Canis familiaris |
Query 129 THRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
|||| | | |||#+|+ +|||||||||||||||||||||||||
Sbjct 429 THRVPDAKLQPLH#TKMDVIKKGHAKDSQRYKVDYESQSTDTQN 471
|
| Capra hircus |
Query 112 SEEDRXXXXXXXXXXXXTHRVSDPKFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
|||| | || | | | |#+|+ +|||||||||||||||||||||||||
Sbjct 5 SEEDHSMGSTENQALPTTRRVPDSKSHLAH#TKMDVIKKGHAKDSQRYKVDYESQSTDTQN 64
|
| Ovis aries |
Query 136 KFHPLH#SKIIIIKKGHAKDSQRYKVDYESQSTDTQN 171
||||+|#+|+ +|||||||||||||||||||||||||
Sbjct 1 KFHPIH#TKMDVIKKGHAKDSQRYKVDYESQSTDTQN 36
|
