XSB2605 : insulin-like growth factor-binding protein
[ CaMP Format ]
This entry is computationally expanded from SB0098
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | Insulin-like growth factor-binding protein 3; IGF-binding protein 3; IGFBP-3; IBP-3 |
| Gene Names | IGFBP1; IBP3 |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| AAA52541 | N/A | N/A | IBP3_HUMAN | N/A | N/A | N/A | hsa:3486 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 291 aa
Average Mass: 31.660 kDa
Monoisotopic Mass: 31.640 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| IGFBP 1. | 40 | 99 | 99.8 | 9.1e-27 |
| --- cleavage 169 --- | ||||
| Thyroglobulin_1 1. | 213 | 285 | 121.6 | 2.6e-33 |
3. Sequence Information
Fasta Sequence: XSB2605.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] VSDPKFHPLH169-SKIIIIKKGH
His169 
Ser
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Val160 | Ser161 | Asp162 | Pro163 | Lys164 | Phe165 | His166 | Pro167 | Leu168 | His169 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser170 | Lys171 | Ile172 | Ile173 | Ile174 | Ile175 | Lys176 | Lys177 | Gly178 | His179 |
Sequence conservation (by blast)
* References
[PubMed ID: 2464130] Wood WI, Cachianes G, Henzel WJ, Winslow GA, Spencer SA, Hellmiss R, Martin JL, Baxter RC, Cloning and expression of the growth hormone-dependent insulin-like growth factor-binding protein. Mol Endocrinol. 1988 Dec;2(12):1176-85.