logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2680 : Chain D, Actin Filament Model In The Extended Form Of Acromsomal Bundle In The Limulus Sperm

[ CaMP Format ]

This entry is computationally expanded from SB0071

* Basic Information

OrganismLimulus polyphemus (Atlantic horseshoe crab)
Protein NamesActin-3
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
3B63_D N/A N/A ACT3_LIMPO N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 357 aa

Average Mass: 39.793 kDa

Monoisotopic Mass: 39.767 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Actin 1. 1357746.71.7e-221
--- cleavage 31 (inside Actin 1..357) ---

3. Sequence Information

Fasta Sequence: XSB2680.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 3B63 (EM; -; A/G=7-371, B=8-371, C/I=7-371, D=8-365, E/H/J/K/N=8-371, F=8-363, L/M=7-371)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] RAVFPSIVGR31-PRHQGVMVGM

Arg31 Pro

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Arg22Ala23Val24Phe25Pro26Ser27Ile28Val29Gly30Arg31
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Pro32Arg33His34Gln35Gly36Val37Met38Val39Gly40Met41

Sequence conservation (by blast)

* References

[PubMed ID: 18022194] Cong Y, Topf M, Sali A, Matsudaira P, Dougherty M, Chiu W, Schmid MF, Crystallographic conformers of actin in a biologically active bundle of filaments. J Mol Biol. 2008 Jan 11;375(2):331-6. Epub 2007 Oct 16.