XSB2823 : myocilin [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0099
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | Myocilin; Trabecular meshwork-induced glucocorticoid response protein |
| Gene Names | GLC1A, TIGR; GLC1A; TIGR |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| BAA24532 | N/A | N/A | MYOC_HUMAN | N/A | N/A | N/A | hsa:4653 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 490 aa
Average Mass: 55.336 kDa
Monoisotopic Mass: 55.302 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| M 1. | 119 | 139 | 8.9 | 9.7 |
| M 2. | 140 | 160 | 4.3 | 40 |
| --- cleavage 212 --- | ||||
| OLF 1. | 232 | 489 | 488.6 | 8.8e-144 |
3. Sequence Information
Fasta Sequence: XSB2823.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] SELTEVPASR212-ILKESPSGYL
Arg212 
Ile
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ser203 | Glu204 | Leu205 | Thr206 | Glu207 | Val208 | Pro209 | Ala210 | Ser211 | Arg212 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ile213 | Leu214 | Lys215 | Glu216 | Ser217 | Pro218 | Ser219 | Gly220 | Tyr221 | Leu222 |
Sequence conservation (by blast)
* References
[PubMed ID: 8749308] Escribano J, Ortego J, Coca-Prados M, Isolation and characterization of cell-specific cDNA clones from a subtractive library of the ocular ciliary body of a single normal human donor: transcription and synthesis of plasma proteins. J Biochem. 1995 Nov;118(5):921-31.