XSB2840 : filamin A alpha [synthetic construct]
[ CaMP Format ]
This entry is computationally expanded from SB0090
* Basic Information
| Organism | synthetic construct |
| Protein Names | filamin A alpha |
| Gene Names | FLNA |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| BAG72555 | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 2639 aa
Average Mass: 280.012 kDa
Monoisotopic Mass: 279.838 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| CH 1. | 44 | 149 | 108.9 | 1.7e-29 |
| CH 2. | 167 | 269 | 99.6 | 1.1e-26 |
| Filamin 1. | 278 | 371 | 120.4 | 5.9e-33 |
| Filamin 2. | 378 | 471 | 128.7 | 1.9e-35 |
| Filamin 3. | 477 | 567 | 133.3 | 7.9e-37 |
| Filamin 4. | 573 | 660 | 107.3 | 5e-29 |
| Filamin 5. | 669 | 760 | 143.6 | 6.3e-40 |
| Filamin 6. | 766 | 863 | 123.9 | 5.4e-34 |
| Filamin 7. | 869 | 962 | 129.4 | 1.1e-35 |
| Filamin 8. | 968 | 1058 | 102.9 | 1.1e-27 |
| Filamin 9. | 1064 | 1151 | 158.5 | 2e-44 |
| Filamin 10. | 1157 | 1246 | 134.1 | 4.5e-37 |
| Filamin 11. | 1252 | 1346 | 118.3 | 2.6e-32 |
| Filamin 12. | 1352 | 1439 | 151.8 | 2e-42 |
| Filamin 13. | 1445 | 1536 | 152.9 | 9.8e-43 |
| Filamin 14. | 1542 | 1633 | 147.1 | 5.4e-41 |
| Filamin 15. | 1639 | 1729 | 126.0 | 1.2e-34 |
| --- cleavage 1761 --- | ||||
| Filamin 16. | 1765 | 1849 | 38.8 | 2.2e-08 |
| Filamin 17. | 1854 | 1941 | 155.8 | 1.3e-43 |
| Filamin 18. | 1942 | 2028 | 25.5 | 6.3e-05 |
| Filamin 19. | 2036 | 2123 | 146.4 | 8.8e-41 |
| Filamin 20. | 2142 | 2219 | 19.0 | 0.00025 |
| Filamin 21. | 2227 | 2314 | 139.8 | 8.6e-39 |
| Filamin 22. | 2321 | 2409 | 91.0 | 4.1e-24 |
| Filamin 23. | 2418 | 2505 | 127.2 | 5.4e-35 |
| Filamin 24. | 2546 | 2635 | 115.3 | 2e-31 |
3. Sequence Information
Fasta Sequence: XSB2840.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] QYTYAQGGQQ1761-TWAPERPLVG
Gln1761 
Thr
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gln1752 | Tyr1753 | Thr1754 | Tyr1755 | Ala1756 | Gln1757 | Gly1758 | Gly1759 | Gln1760 | Gln1761 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr1762 | Trp1763 | Ala1764 | Pro1765 | Glu1766 | Arg1767 | Pro1768 | Leu1769 | Val1770 | Gly1771 |
Sequence conservation (by blast)
* References
[PubMed ID: 18316326] Nagase T, Yamakawa H, Tadokoro S, Nakajima D, Inoue S, Yamaguchi K, Itokawa Y, Kikuno RF, Koga H, Ohara O, Exploration of human ORFeome: high-throughput preparation of ORF clones and efficient characterization of their protein products. DNA Res. 2008 Jun 30;15(3):137-49. Epub 2008 Mar 2.