XSB2841 : filamin A [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0090
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | filamin A |
| Gene Names | FLNA |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| BAG48306 | N/A | N/A | B2ZZ80_HUMAN | N/A | N/A | N/A | hsa: |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 2315 aa
Average Mass: 245.867 kDa
Monoisotopic Mass: 245.713 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| CH 1. | 17 | 122 | 108.9 | 1.7e-29 |
| CH 2. | 140 | 242 | 99.6 | 1.1e-26 |
| Filamin 1. | 251 | 344 | 120.4 | 5.9e-33 |
| Filamin 2. | 351 | 444 | 128.7 | 1.9e-35 |
| Filamin 3. | 450 | 540 | 133.3 | 7.9e-37 |
| Filamin 4. | 546 | 633 | 107.3 | 5e-29 |
| Filamin 5. | 642 | 733 | 148.4 | 2.2e-41 |
| Filamin 6. | 739 | 836 | 123.9 | 5.4e-34 |
| Filamin 7. | 842 | 935 | 129.4 | 1.1e-35 |
| Filamin 8. | 941 | 1031 | 102.9 | 1.1e-27 |
| Filamin 9. | 1037 | 1124 | 158.5 | 2e-44 |
| Filamin 10. | 1130 | 1219 | 134.1 | 4.5e-37 |
| Filamin 11. | 1225 | 1319 | 118.3 | 2.6e-32 |
| Filamin 12. | 1325 | 1412 | 151.8 | 2e-42 |
| Filamin 13. | 1418 | 1509 | 152.9 | 9.8e-43 |
| Filamin 14. | 1515 | 1606 | 147.1 | 5.4e-41 |
| Filamin 15. | 1612 | 1710 | 104.8 | 2.8e-28 |
| --- cleavage 1742 --- | ||||
| Filamin 16. | 1746 | 1830 | 38.8 | 2.2e-08 |
| Filamin 17. | 1835 | 1922 | 155.8 | 1.3e-43 |
| Filamin 18. | 1923 | 1990 | 23.9 | 9e-05 |
| Filamin 19. | 1997 | 2085 | 91.4 | 3.2e-24 |
| Filamin 20. | 2094 | 2181 | 127.2 | 5.4e-35 |
| Filamin 21. | 2222 | 2311 | 115.3 | 2e-31 |
3. Sequence Information
Fasta Sequence: XSB2841.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] QYTYAQGGQQ1742-TWAPERPLVG
Gln1742 
Thr
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gln1733 | Tyr1734 | Thr1735 | Tyr1736 | Ala1737 | Gln1738 | Gly1739 | Gly1740 | Gln1741 | Gln1742 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr1743 | Trp1744 | Ala1745 | Pro1746 | Glu1747 | Arg1748 | Pro1749 | Leu1750 | Val1751 | Gly1752 |
Sequence conservation (by blast)
* References
[PubMed ID: 18487259] Oshikawa M, Sugai Y, Usami R, Ohtoko K, Toyama S, Kato S, Fine expression profiling of full-length transcripts using a size-unbiased cDNA library prepared with the vector-capping method. DNA Res. 2008 Jun 30;15(3):123-36. Epub 2008 May 16.