XSB2847 : filamin A, alpha isoform 2 (predicted) [Oryctolagus cuniculus]
[ CaMP Format ]
This entry is computationally expanded from SB0090
* Basic Information
| Organism | Oryctolagus cuniculus (rabbit) |
| Protein Names | Filamin A, alpha isoform 2 (Predicted); filamin A; alpha isoform 2 (predicted); SubName: Full=Filamin A; alpha isoform 2; Predicted |
| Gene Names | FLNA |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein |
Entrez Nucleotide |
Entrez Gene |
UniProt |
OMIM |
HGNC |
HPRD |
KEGG |
| ACK44274 |
N/A |
N/A |
B7NZP9_RABIT |
N/A |
N/A |
N/A |
N/A |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 2646 aa
Average Mass: 280.430 kDa
Monoisotopic Mass: 280.255 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| CH 1. | 43 | 148 | 108.9 | 1.7e-29 |
| CH 2. | 166 | 268 | 102.9 | 1.1e-27 |
| Filamin 1. | 277 | 370 | 120.4 | 5.9e-33 |
| Filamin 2. | 377 | 470 | 131.1 | 3.4e-36 |
| Filamin 3. | 476 | 566 | 126.8 | 6.9e-35 |
| Filamin 4. | 572 | 659 | 107.3 | 5e-29 |
| Filamin 5. | 668 | 759 | 149.9 | 7.7e-42 |
| Filamin 6. | 765 | 862 | 124.7 | 3e-34 |
| Filamin 7. | 868 | 961 | 127.9 | 3.3e-35 |
| Filamin 8. | 967 | 1057 | 102.4 | 1.5e-27 |
| Filamin 9. | 1063 | 1150 | 158.5 | 2e-44 |
| Filamin 10. | 1156 | 1245 | 133.1 | 8.8e-37 |
| Filamin 11. | 1251 | 1345 | 118.2 | 2.8e-32 |
| Filamin 12. | 1351 | 1438 | 151.8 | 2e-42 |
| Filamin 13. | 1444 | 1535 | 152.0 | 1.9e-42 |
| Filamin 14. | 1541 | 1632 | 147.1 | 5.4e-41 |
| Filamin 15. | 1638 | 1736 | 104.8 | 2.8e-28 |
| --- cleavage 1768 --- |
| Filamin 16. | 1772 | 1856 | 38.2 | 3.4e-08 |
| Filamin 17. | 1861 | 1948 | 158.1 | 2.6e-44 |
| Filamin 18. | 1949 | 2035 | 25.5 | 6.3e-05 |
| Filamin 19. | 2043 | 2130 | 149.2 | 1.2e-41 |
| Filamin 20. | 2149 | 2226 | 19.3 | 0.00023 |
| Filamin 21. | 2234 | 2321 | 139.8 | 8.6e-39 |
| Filamin 22. | 2328 | 2416 | 89.3 | 1.4e-23 |
| Filamin 23. | 2425 | 2512 | 128.1 | 2.9e-35 |
| Filamin 24. | 2553 | 2642 | 111.6 | 2.7e-30 |
3. Sequence Information
Fasta Sequence: XSB2847.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] QYTYAQGGQQ1768-TWAPERPLVG
Gln1768 
Thr
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Gln1759 | Tyr1760 | Thr1761 | Tyr1762 | Ala1763 | Gln1764 | Gly1765 | Gly1766 | Gln1767 | Gln1768 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Thr1769 | Trp1770 | Ala1771 | Pro1772 | Glu1773 | Arg1774 | Pro1775 | Leu1776 | Val1777 | Gly1778 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
ALAGEQPAAQPPLRPQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTI
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Homo sapiens |
86.70 |
16 |
FLNA_HUMAN Filamin-A (Alpha-filamin) (Filamin-1) ( |
| 2 |
Canis familiaris |
85.50 |
13 |
PREDICTED: similar to Filamin A (Alpha-filamin) (F |
| 3 |
Macaca mulatta |
85.50 |
5 |
PREDICTED: filamin 1 (actin-binding protein-280) i |
| 4 |
Bos taurus |
85.10 |
2 |
PREDICTED: similar to filamin |
| 5 |
Rattus norvegicus |
79.70 |
3 |
PREDICTED: similar to Filamin-A (Alpha-filamin) (F |
| 6 |
Mus musculus |
77.80 |
12 |
filamin, alpha |
| 7 |
N/A |
77.80 |
1 |
F |
| 8 |
Gallus gallus |
46.60 |
2 |
filamin |
| 9 |
Tetraodon nigroviridis |
43.90 |
2 |
unnamed protein product |
| 10 |
Pan troglodytes |
36.20 |
3 |
PREDICTED: filamin B, beta (actin binding protein |
| 11 |
Danio rerio |
35.80 |
1 |
PREDICTED: similar to gamma-filamin |
Top-ranked sequences
| organism | matching |
|---|
| Homo sapiens |
Query 1739 ALAGEXXXXXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
||||+ |||||||||#||||||||||||||||||||||||||||||
Sbjct 1740 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1799
|
| Canis familiaris |
Query 1739 ALAGEXXXXXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
||||+ |||||||||#||||||||+|||||||||||||||||||||
Sbjct 1740 ALAGDQPAAQPPLRPQQLAPPYTYAQGGQQ#TWAPERPLMGVNGLDVTSLRPFDLVIPFTI 1799
|
| Macaca mulatta |
Query 1739 ALAGEXXXXXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
||||+ |||||||||#|||||||||||||||+||||||||||||||
Sbjct 1740 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDMTSLRPFDLVIPFTI 1799
|
| Bos taurus |
Query 1739 ALAGEXXXXXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
||||+ |||||||||#||||||||||||||||+|||||||||||||
Sbjct 2023 ALAGDQPTAQPSLRPQQLAPPYTYAQGGQQ#TWAPERPLVGVNGLDVSSLRPFDLVIPFTI 2082
|
| Rattus norvegicus |
Query 1739 ALAGEXXXXXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
||||+ ||| || ||#|| ||||+||||||||||||||||||||||
Sbjct 1740 ALAGDQPTVQTPLRPQQLPSQYTYPQGSQQ#TWIPERPMVGVNGLDVTSLRPFDLVIPFTI 1799
|
| Mus musculus |
Query 1739 ALAGEXXXXXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
||||+ | | || ||#|| ||||+||||||||||||||||||||||
Sbjct 1732 ALAGDQPTVQTPLRSQQLAPQYNYPQGSQQ#TWIPERPMVGVNGLDVTSLRPFDLVIPFTI 1791
|
| N/A |
Query 1739 ALAGEXXXXXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
||||+ | | || ||#|| ||||+||||||||||||||||||||||
Sbjct 1740 ALAGDQPTVQTPLRSQQLAPQYNYPQGSQQ#TWIPERPMVGVNGLDVTSLRPFDLVIPFTI 1799
|
| Gallus gallus |
Query 1768 Q#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
|# | ||||+||||||| ||||||||| ||
Sbjct 1719 Q#VMATERPLLGVNGLDV-GLRPFDLVIPLTI 1748
|
| Tetraodon nigroviridis |
Query 1771 APERPLVGVNGLDVTSLRPFDLVIPFTI 1798
| +||+ |+||||| ||||||||||||
Sbjct 1718 ATDRPM-GMNGLDVAGLRPFDLVIPFTI 1744
|
| Pan troglodytes |
Query 1760 YTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
+|+ + | #|| | | |+ ++ +|||||||| +
Sbjct 1737 HTFMKTKQL#TWVTEEAYVPVSNMNGLGFKPFDLVIPFAV 1775
|
| Danio rerio |
Query 1760 YTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1798
| || # || | |+ |+ ++ ||||+||||||+
Sbjct 1291 YAPYQGYSP#HWATEEPVTAVDIIEPV-LRPFNLVIPFTV 1328
|
