XSB2849 : filamin A, alpha isoform 2 (predicted) [Rhinolophus ferrumequinum]
[ CaMP Format ]
This entry is computationally expanded from SB0090
* Basic Information
| Organism | Rhinolophus ferrumequinum (greater horseshoe bat) |
| Protein Names | Filamin A, alpha isoform 2 (Predicted); filamin A; alpha isoform 2 (predicted); SubName: Full=Filamin A; alpha isoform 2; Predicted |
| Gene Names | FLNA |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein |
Entrez Nucleotide |
Entrez Gene |
UniProt |
OMIM |
HGNC |
HPRD |
KEGG |
| ACC68902 |
N/A |
N/A |
B2KIJ4_RHIFE |
N/A |
N/A |
N/A |
N/A |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 2637 aa
Average Mass: 279.464 kDa
Monoisotopic Mass: 279.289 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| CH 1. | 34 | 139 | 105.8 | 1.4e-28 |
| CH 2. | 157 | 259 | 102.9 | 1.1e-27 |
| Filamin 1. | 268 | 361 | 120.4 | 5.9e-33 |
| Filamin 2. | 368 | 461 | 134.9 | 2.6e-37 |
| Filamin 3. | 467 | 557 | 131.9 | 2.1e-36 |
| Filamin 4. | 563 | 650 | 107.3 | 5e-29 |
| Filamin 5. | 659 | 750 | 149.1 | 1.4e-41 |
| Filamin 6. | 756 | 853 | 124.7 | 3e-34 |
| Filamin 7. | 859 | 952 | 129.3 | 1.2e-35 |
| Filamin 8. | 958 | 1048 | 103.8 | 5.8e-28 |
| Filamin 9. | 1054 | 1141 | 158.5 | 2e-44 |
| Filamin 10. | 1147 | 1236 | 137.4 | 4.6e-38 |
| Filamin 11. | 1242 | 1336 | 110.1 | 7.5e-30 |
| Filamin 12. | 1342 | 1429 | 151.8 | 2e-42 |
| Filamin 13. | 1435 | 1526 | 152.0 | 1.9e-42 |
| Filamin 14. | 1532 | 1623 | 147.1 | 5.4e-41 |
| Filamin 15. | 1629 | 1727 | 104.8 | 2.8e-28 |
| --- cleavage 1759 --- |
| Filamin 16. | 1763 | 1847 | 35.8 | 1.8e-07 |
| Filamin 17. | 1852 | 1939 | 155.1 | 2.1e-43 |
| Filamin 18. | 1940 | 2026 | 25.6 | 6.3e-05 |
| Filamin 19. | 2034 | 2121 | 146.4 | 8.8e-41 |
| Filamin 20. | 2140 | 2217 | 23.8 | 9.2e-05 |
| Filamin 21. | 2225 | 2312 | 139.8 | 8.6e-39 |
| Filamin 22. | 2319 | 2407 | 89.7 | 1e-23 |
| Filamin 23. | 2416 | 2503 | 127.9 | 3.3e-35 |
| Filamin 24. | 2544 | 2633 | 110.1 | 7.3e-30 |
3. Sequence Information
Fasta Sequence: XSB2849.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] PYTYAQGGQQ1759-TWAPERPLVG
Gln1759 
Thr
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Pro1750 | Tyr1751 | Thr1752 | Tyr1753 | Ala1754 | Gln1755 | Gly1756 | Gly1757 | Gln1758 | Gln1759 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Thr1760 | Trp1761 | Ala1762 | Pro1763 | Glu1764 | Arg1765 | Pro1766 | Leu1767 | Val1768 | Gly1769 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
ALAGDQPTSQAPLRPQQLAPPYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTI
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Bos taurus |
95.10 |
2 |
PREDICTED: similar to filamin |
| 2 |
Homo sapiens |
94.00 |
17 |
filamin A, alpha |
| 3 |
Canis familiaris |
93.60 |
13 |
PREDICTED: similar to Filamin A (Alpha-filamin) (F |
| 4 |
Macaca mulatta |
92.80 |
5 |
PREDICTED: filamin 1 (actin-binding protein-280) i |
| 5 |
Rattus norvegicus |
88.60 |
3 |
PREDICTED: similar to Filamin-A (Alpha-filamin) (F |
| 6 |
Mus musculus |
86.70 |
12 |
filamin, alpha |
| 7 |
N/A |
86.70 |
1 |
F |
| 8 |
Gallus gallus |
46.60 |
2 |
filamin |
| 9 |
Tetraodon nigroviridis |
43.90 |
2 |
unnamed protein product |
| 10 |
Pan troglodytes |
36.20 |
3 |
PREDICTED: filamin B, beta (actin binding protein |
| 11 |
Danio rerio |
35.80 |
1 |
PREDICTED: similar to gamma-filamin |
Top-ranked sequences
| organism | matching |
|---|
| Bos taurus |
Query 1730 ALAGDQPTSXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
||||||||+ |||||||||#||||||||||||||||+|||||||||||||
Sbjct 2023 ALAGDQPTAQPSLRPQQLAPPYTYAQGGQQ#TWAPERPLVGVNGLDVSSLRPFDLVIPFTI 2082
|
| Homo sapiens |
Query 1730 ALAGDQPTSXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
|||||||+ |||||||||#||||||||||||||||||||||||||||||
Sbjct 1732 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1791
|
| Canis familiaris |
Query 1730 ALAGDQPTSXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
||||||| + |||||||||#||||||||+|||||||||||||||||||||
Sbjct 1732 ALAGDQPAAQPPLRPQQLAPPYTYAQGGQQ#TWAPERPLMGVNGLDVTSLRPFDLVIPFTI 1791
|
| Macaca mulatta |
Query 1730 ALAGDQPTSXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
|||||||+ |||||||||#|||||||||||||||+||||||||||||||
Sbjct 1740 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDMTSLRPFDLVIPFTI 1799
|
| Rattus norvegicus |
Query 1730 ALAGDQPTSXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
|||||||| ||| || ||#|| ||||+||||||||||||||||||||||
Sbjct 1740 ALAGDQPTVQTPLRPQQLPSQYTYPQGSQQ#TWIPERPMVGVNGLDVTSLRPFDLVIPFTI 1799
|
| Mus musculus |
Query 1730 ALAGDQPTSXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
|||||||| | | || ||#|| ||||+||||||||||||||||||||||
Sbjct 1732 ALAGDQPTVQTPLRSQQLAPQYNYPQGSQQ#TWIPERPMVGVNGLDVTSLRPFDLVIPFTI 1791
|
| N/A |
Query 1730 ALAGDQPTSXXXXXXXXXXXXYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
|||||||| | | || ||#|| ||||+||||||||||||||||||||||
Sbjct 1740 ALAGDQPTVQTPLRSQQLAPQYNYPQGSQQ#TWIPERPMVGVNGLDVTSLRPFDLVIPFTI 1799
|
| Gallus gallus |
Query 1759 Q#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
|# | ||||+||||||| ||||||||| ||
Sbjct 1719 Q#VMATERPLLGVNGLDV-GLRPFDLVIPLTI 1748
|
| Tetraodon nigroviridis |
Query 1762 APERPLVGVNGLDVTSLRPFDLVIPFTI 1789
| +||+ |+||||| ||||||||||||
Sbjct 1718 ATDRPM-GMNGLDVAGLRPFDLVIPFTI 1744
|
| Pan troglodytes |
Query 1751 YTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
+|+ + | #|| | | |+ ++ +|||||||| +
Sbjct 1737 HTFMKTKQL#TWVTEEAYVPVSNMNGLGFKPFDLVIPFAV 1775
|
| Danio rerio |
Query 1751 YTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 1789
| || # || | |+ |+ ++ ||||+||||||+
Sbjct 1291 YAPYQGYSP#HWATEEPVTAVDIIEPV-LRPFNLVIPFTV 1328
|
