logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2872 : insulin-like growth factor binding protein 5, isoform CRA_b [Mus musculus]

[ CaMP Format ]

This entry is computationally expanded from SB0023

* Basic Information

OrganismMus musculus (house mouse)
Protein Namesinsulin-like growth factor binding protein 5; isoform CRA_b
Gene NamesIgfbp5
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
EDL00295 N/A 16011 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 333 aa

Average Mass: 37.288 kDa

Monoisotopic Mass: 37.264 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
IGFBP 1. 88146102.71.3e-27
--- cleavage 233 ---
--- cleavage 222 ---
Thyroglobulin_1 1. 253324130.36.3e-36

3. Sequence Information

Fasta Sequence: XSB2872.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] SKFVGGAENT233-AHPRVIPAPE

Thr233 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ser224Lys225Phe226Val227Gly228Gly229Ala230Glu231Asn232Thr233
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala234His235Pro236Arg237Val238Ile239Pro240Ala241Pro242Glu243

Sequence conservation (by blast)

[Site 2] VKKDRRKKLT222-QSKFVGGAEN

Thr222 Gln

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Val213Lys214Lys215Asp216Arg217Arg218Lys219Lys220Leu221Thr222
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gln223Ser224Lys225Phe226Val227Gly228Gly229Ala230Glu231Asn232

Sequence conservation (by blast)

* References

[PubMed ID: 12040188] Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD, A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science. 2002 May 31;296(5573):1661-71.