XSB2889 : PREDICTED: spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) isoform 1 [Taeniopygia guttata]
[ CaMP Format ]
This entry is computationally expanded from SB0061
* Basic Information
| Organism | Taeniopygia guttata |
| Protein Names | spectrin; alpha; non-erythrocytic 1 (alpha-fodrin) isoform 1 |
| Gene Names | LOC100217607; gene.420194; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 6 mRNAs, 84 ESTs, 3 Proteins |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 2476 aa
Average Mass: 285.235 kDa
Monoisotopic Mass: 285.060 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| Spectrin 1. | 44 | 147 | 123.6 | 6.4e-34 |
| Spectrin 2. | 149 | 253 | 132.6 | 1.3e-36 |
| Spectrin 3. | 255 | 359 | 132.7 | 1.2e-36 |
| Spectrin 4. | 361 | 465 | 114.9 | 2.7e-31 |
| Spectrin 5. | 467 | 571 | 126.5 | 8.9e-35 |
| Spectrin 6. | 573 | 676 | 127.0 | 6e-35 |
| Spectrin 7. | 678 | 782 | 143.7 | 5.7e-40 |
| Spectrin 8. | 784 | 888 | 152.8 | 1e-42 |
| SH3_1 1. | 970 | 1024 | 78.9 | 1.8e-20 |
| Spectrin 9. | 1091 | 1230 | 70.6 | 5.7e-18 |
| --- cleavage 1176 (inside Spectrin 1091..1230) --- |
| Spectrin 10. | 1232 | 1336 | 147.4 | 4.4e-41 |
| Spectrin 11. | 1338 | 1442 | 115.4 | 1.9e-31 |
| Spectrin 12. | 1444 | 1548 | 116.3 | 9.9e-32 |
| Spectrin 13. | 1550 | 1660 | 86.0 | 1.3e-22 |
| Spectrin 14. | 1662 | 1766 | 133.7 | 5.8e-37 |
| Spectrin 15. | 1768 | 1872 | 149.2 | 1.2e-41 |
| Spectrin 16. | 1874 | 1978 | 126.9 | 6.3e-35 |
| Spectrin 17. | 1980 | 2085 | 117.2 | 5.5e-32 |
| Spectrin 18. | 2095 | 2199 | 72.2 | 1.9e-18 |
| Spectrin 19. | 2209 | 2314 | 68.7 | 2.1e-17 |
| efhand 1. | 2331 | 2359 | 36.5 | 1e-07 |
| efhand 2. | 2374 | 2402 | 22.4 | 0.0019 |
| efhand_Ca_insen 1. | 2406 | 2475 | 48.4 | 2.8e-11 |
3. Sequence Information
Fasta Sequence: XSB2889.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] VQAVQQQEVY1176-GMPRDETDSK
Tyr1176 
Gly
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Val1167 | Gln1168 | Ala1169 | Val1170 | Gln1171 | Gln1172 | Gln1173 | Glu1174 | Val1175 | Tyr1176 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Gly1177 | Met1178 | Pro1179 | Arg1180 | Asp1181 | Glu1182 | Thr1183 | Asp1184 | Ser1185 | Lys1186 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
LKDINKVAKDLESEGLMADEVQAVQQQEVYGMPRDETDSKTASPWKSARLMVHTVATFNS
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Homo sapiens |
92.00 |
16 |
alpha II spectrin |
| 2 |
N/A |
92.00 |
4 |
- |
| 3 |
Monodelphis domestica |
90.90 |
2 |
PREDICTED: similar to spectrin alpha 2 isoform 1 |
| 4 |
Canis familiaris |
90.90 |
1 |
PREDICTED: similar to Spectrin alpha chain, brain |
| 5 |
Bos taurus |
90.50 |
2 |
PREDICTED: similar to SPTAN1 protein isoform 2 |
| 6 |
Mus musculus |
90.10 |
19 |
spectrin alpha 2 |
| 7 |
Rattus norvegicus |
90.10 |
3 |
alpha-spectrin 2 |
| 8 |
Gallus gallus |
89.40 |
3 |
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) |
| 9 |
Xenopus tropicalis |
72.80 |
1 |
hypothetical protein LOC100036647 |
| 10 |
Tetraodon nigroviridis |
60.50 |
2 |
unnamed protein product |
| 11 |
Danio rerio |
58.90 |
1 |
alpha II-spectrin |
Top-ranked sequences
| organism | matching |
|---|
| Homo sapiens |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#GM-PRDETDSKTASPWKSARLMVHTVATFN 1205
||||||||+|||||||||+ |#|| |||||||||||||||||||||||||||
Sbjct 1147 LKDINKVAEDLESEGLMAEEVQAVQQQEVY#GMMPRDETDSKTASPWKSARLMVHTVATFN 1206
Query 1206 S 1206
|
Query 1206 S 1206
|
| N/A |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#GM-PRDETDSKTASPWKSARLMVHTVATFN 1205
||||||||+|||||||||+ |#|| |||||||||||||||||||||||||||
Sbjct 472 LKDINKVAEDLESEGLMAEEVQAVQQQEVY#GMMPRDETDSKTASPWKSARLMVHTVATFN 531
Query 1206 S 1206
|
Query 1206 S 1206
|
| Monodelphis domestica |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#GM-PRDETDSKTASPWKSARLMVHTVATFN 1205
||||||||+|||||||||+ |#|| |||+|||||||||||||||||||||||
Sbjct 1127 LKDINKVAEDLESEGLMAEEVQAVQQQEVY#GMMPRDDTDSKTASPWKSARLMVHTVATFN 1186
Query 1206 S 1206
|
Query 1206 S 1206
|
| Canis familiaris |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#GM-PRDETDSKTASPWKSARLMVHTVATFN 1205
||||||||+|||||||||+ |#|| |||+|||||||||||||||||||||||
Sbjct 1243 LKDINKVAEDLESEGLMAEEVQAVQQQEVY#GMMPRDDTDSKTASPWKSARLMVHTVATFN 1302
Query 1206 S 1206
|
Query 1206 S 1206
|
| Bos taurus |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#G-MPRDETDSKTASPWKSARLMVHTVATFN 1205
||||||||+|||||||||+ |#| |||||+||||||||||||||||||||||
Sbjct 1147 LKDINKVAEDLESEGLMAEEVQAVQQQEVY#GAMPRDESDSKTASPWKSARLMVHTVATFN 1206
Query 1206 S 1206
|
Query 1206 S 1206
|
| Mus musculus |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#G-MPRDETDSKTASPWKSARLMVHTVATFN 1205
||||||||+|||||||||+ |#| ||||| ||||||||||||||||||||||
Sbjct 1147 LKDINKVAEDLESEGLMAEEVQAVQQQEVY#GAMPRDEADSKTASPWKSARLMVHTVATFN 1206
Query 1206 S 1206
|
Query 1206 S 1206
|
| Rattus norvegicus |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#GM-PRDETDSKTASPWKSARLMVHTVATFN 1205
||||||||+|||||||||+ |#|| |||| ||||||||||||||||||||||
Sbjct 1147 LKDINKVAEDLESEGLMAEEVQAVQQQEVY#GMMPRDEADSKTASPWKSARLMVHTVATFN 1206
Query 1206 S 1206
|
Query 1206 S 1206
|
| Gallus gallus |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#GM-PRDETDSKTASPWKSARLMVHTVATFN 1205
|||||||| |||||||||+ |#|| ||||||||| |||||||+|||||||||
Sbjct 1147 LKDINKVANDLESEGLMAEEVQAVEHQEVY#GMMPRDETDSKTVSPWKSARMMVHTVATFN 1206
Query 1206 S 1206
|
Query 1206 S 1206
|
| Xenopus tropicalis |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#GMPRDETDSKTASPWKSARLMVHTVATFNS 1206
|||||||| +||||||+ + |#|| ||| |||+|||||| | | ||||||
Sbjct 1147 LKDINKVADELESEGLITEEVQPVQHQEVY#GMQRDEADSKSASPWKSVRTAVLAVATFNS 1206
|
| Tetraodon nigroviridis |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#GM-----PRDETDSKTASPWKSARLMVHTV 1201
|+|||||| +||||||||+ # + +|| |||||||||+ || | |
Sbjct 1267 LRDINKVAAELESEGLMAEETPMVQAQQQQ#ELLGAAPGKDEADSKTASPWKNVRLAVQTT 1326
Query 1202 ATFNS 1206
| ||+
Sbjct 1327 ANFNT 1331
|
| Danio rerio |
Query 1147 LKDINKVAKDLESEGLMADXXXXXXXXXXY#GMP----RDETDSKTASPWKSARLMVHTVA 1202
|+|||||| +||||||||+ # + +|| ||| |||||| || | | |
Sbjct 1147 LRDINKVASELESEGLMAEEAPVVQAQQVE#VLGSAPGKDEADSKGASPWKSVRLAVQTTA 1206
Query 1203 TFNS 1206
||+
Sbjct 1207 NFNT 1210
|
