XSB2923 : huntingtin [Callithrix jacchus]
[ CaMP Format ]
This entry is computationally expanded from SB0051
* Basic Information
| Organism | Callithrix jacchus (white-tufted-ear marmoset) |
| Protein Names | huntingtin |
| Gene Names | Htt |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein |
Entrez Nucleotide |
Entrez Gene |
UniProt |
OMIM |
HGNC |
HPRD |
KEGG |
| BAH03657 |
N/A |
N/A |
B7XBM1_CALJA |
N/A |
N/A |
N/A |
N/A |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 3131 aa
Average Mass: 346.333 kDa
Monoisotopic Mass: 346.113 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| HEAT 1. | 112 | 148 | 16.7 | 0.094 |
| HEAT 2. | 193 | 229 | 6.9 | 6.9 |
| HEAT 3. | 236 | 271 | 15.2 | 0.27 |
| DUF1242 1. | 300 | 329 | -5.9 | 5.1 |
| HEAT 4. | 342 | 377 | 5.4 | 11 |
| --- cleavage 524 --- |
| DUF801 1. | 548 | 576 | 9.4 | 1.2 |
| HEAT 5. | 737 | 769 | 0.9 | 38 |
| HEAT 6. | 791 | 827 | 6.9 | 6.9 |
| HEAT 7. | 830 | 869 | 0.0 | 49 |
| HEAT 8. | 891 | 928 | 21.2 | 0.0042 |
| Toxin_13 1. | 1005 | 1051 | -9.0 | 9.8 |
| Borrelia_lipo_2 1. | 1384 | 1481 | -26.7 | 8.2 |
| Utp13 1. | 1551 | 1654 | -71.2 | 5.1 |
| Inhibitor_I68 1. | 1666 | 1742 | -46.0 | 7.5 |
| Corona_5a 1. | 1971 | 2027 | -1.4 | 1.3 |
| DUF1969 1. | 2163 | 2232 | -61.6 | 7.2 |
| Bromo_TP 1. | 2333 | 2396 | -16.2 | 9.8 |
| TnsA_C 1. | 2486 | 2557 | -12.9 | 7.9 |
| Cyclase_polyket 1. | 2744 | 2831 | -51.9 | 5.3 |
3. Sequence Information
Fasta Sequence: XSB2923.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] DEEDILSHSS524-SQVSAVPSDP
Ser524 
Ser
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Asp515 | Glu516 | Glu517 | Asp518 | Ile519 | Leu520 | Ser521 | His522 | Ser523 | Ser524 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ser525 | Gln526 | Val527 | Ser528 | Ala529 | Val530 | Pro531 | Ser532 | Asp533 | Pro534 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
LQADSVDLAGCDLTSSATDGDEEDILSHSSSQVSAVPSDPAMDLNDGTQASSPISDSSQT
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
N/A |
82.80 |
6 |
- |
| 2 |
Homo sapiens |
82.80 |
5 |
huntingtin |
| 3 |
Macaca mulatta |
82.80 |
1 |
PREDICTED: huntingtin |
| 4 |
Mus musculus |
82.80 |
1 |
huntingtin |
| 5 |
Rattus norvegicus |
82.80 |
1 |
PREDICTED: similar to Huntingtin (Huntington disea |
| 6 |
Pan troglodytes |
82.80 |
1 |
PREDICTED: huntingtin |
| 7 |
Sus scrofa |
79.00 |
1 |
huntingtin |
| 8 |
Bos taurus |
79.00 |
1 |
PREDICTED: similar to huntingtin |
| 9 |
Canis familiaris |
75.90 |
1 |
PREDICTED: similar to Huntingtin (Huntingtons dise |
| 10 |
Monodelphis domestica |
75.90 |
1 |
PREDICTED: similar to Huntingtons Disease protein |
| 11 |
Gallus gallus |
73.60 |
1 |
PREDICTED: similar to Huntingtons Disease protein |
| 12 |
Xenopus tropicalis |
61.60 |
1 |
huntingtin |
Top-ranked sequences
| organism | matching |
|---|
| N/A |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
||||||||+||||||+|||||||||| # |||||||||||||||||||
Sbjct 484 LQADSVDLSGCDLTSAATDGDEEDILSHSS#SQFSAVPSDPAMDLNDGTQASSPISDSSQT 543
|
| Homo sapiens |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
||||||||| |||||||||||||||| # |||||||||||||||||||
Sbjct 507 LQADSVDLASCDLTSSATDGDEEDILSHSS#SQVSAVPSDPAMDLNDGTQASSPISDSSQT 566
|
| Macaca mulatta |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
||||||||| |||||||||||||||| # |||||||||||||||||||
Sbjct 494 LQADSVDLASCDLTSSATDGDEEDILSHSS#SQVSAVPSDPAMDLNDGTQASSPISDSSQT 553
|
| Mus musculus |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
||||||||+||||||+|||||||||| # |||||||||||||||||||
Sbjct 485 LQADSVDLSGCDLTSAATDGDEEDILSHSS#SQFSAVPSDPAMDLNDGTQASSPISDSSQT 544
|
| Rattus norvegicus |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
||||||||+||||||+|||||||||| # |||||||||||||||||||
Sbjct 485 LQADSVDLSGCDLTSAATDGDEEDILSHSS#SQFSAVPSDPAMDLNDGTQASSPISDSSQT 544
|
| Pan troglodytes |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
||||||||| |||||||||||||||| # |||||||||||||||||||
Sbjct 507 LQADSVDLASCDLTSSATDGDEEDILSHSS#SQVSAVPSDPAMDLNDGTQASSPISDSSQT 566
|
| Sus scrofa |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
|| |||||+||||+|+|||||||||| # ||||||||||||+||||||
Sbjct 504 LQPDSVDLSGCDLSSAATDGDEEDILSHSS#SQMSAVPSDPAMDLNDGTQASSPVSDSSQT 563
|
| Bos taurus |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
|| |+|||| |||||+|||||||||| # |||||||||||||||||||
Sbjct 498 LQTDAVDLAACDLTSAATDGDEEDILSHSS#SQMSAVPSDPAMDLNDGTQASSPISDSSQT 557
|
| Canis familiaris |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
|| ||||| ||| |+|||||||||| # ||||||||||||+||||||
Sbjct 495 LQPDSVDLTSCDLASAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPVSDSSQT 554
|
| Monodelphis domestica |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
||+| ||| ||||||+||||||||+| # +|+||||||||||||||||
Sbjct 498 LQSDPVDLTGCDLTSAATDGDEEDMLSRSS#SQISAVPSDPAVDMNDGTQASSPISDSSQT 557
|
| Gallus gallus |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDGTQASSPISDSSQT 554
||+|||||+ |||||+||+|+++|+| # |||||||||||||||||||
Sbjct 459 LQSDSVDLSSCDLTSTATEGEDDDVLSRSS#SQISAVQSDPTMDLNDGTQASSPISDSSQT 518
|
| Xenopus tropicalis |
Query 495 LQADSVDLAGCDLTSSATDGDEEDILXXXX#XXXXXXXXXXXMDLNDG-TQASSPISDSSQ 553
||+||||++ || |+ |+||||||| # |+||+| ||||||+|||||
Sbjct 436 LQSDSVDISSSDLASTVTEGDEEDILSHSS#SQISTVQSDTNMELNEGTTQASSPVSDSSQ 495
Query 554 T 554
|
Query 554 T 554
|
* References
[PubMed ID: 19073238] Hohjoh H, Akari H, Fujiwara Y, Tamura Y, Hirai H, Wada K, Molecular cloning and characterization of the common marmoset huntingtin gene. Gene. 2009 Mar 1;432(1-2):60-6. Epub 2008 Nov 24.
