XSB2927 : PREDICTED: similar to Huntingtin (Huntington disease protein) (HD protein) [Equus caballus]
[ CaMP Format ]
This entry is computationally expanded from SB0051
* Basic Information
| Organism | Equus caballus (horse) |
| Protein Names | similar to Huntingtin (Huntington disease protein) (HD protein) |
| Gene Names | LOC100053721; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 2 Proteins |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 3100 aa
Average Mass: 342.650 kDa
Monoisotopic Mass: 342.432 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| HEAT 1. | 75 | 111 | 16.0 | 0.16 |
| HEAT 2. | 156 | 192 | 8.0 | 5.1 |
| HEAT 3. | 199 | 234 | 15.3 | 0.25 |
| DUF1242 1. | 263 | 292 | -7.9 | 9.1 |
| HEAT 4. | 305 | 340 | 4.7 | 13 |
| DUF801 1. | 431 | 459 | 2.2 | 22 |
| --- cleavage 494 --- |
| DUF801 2. | 518 | 546 | 8.4 | 1.8 |
| HEAT 5. | 703 | 739 | 7.2 | 6.5 |
| HEAT 6. | 761 | 797 | 7.0 | 6.8 |
| HEAT 7. | 804 | 839 | 1.2 | 36 |
| HEAT 8. | 861 | 898 | 20.0 | 0.01 |
| L_biotic_typeA 1. | 948 | 986 | -19.8 | 8.7 |
| COG5 1. | 1201 | 1288 | -58.2 | 5.2 |
| Borrelia_lipo_2 1. | 1354 | 1451 | -26.7 | 8.2 |
| CobW_C 1. | 1613 | 1708 | -24.5 | 5.2 |
| PerC 1. | 1785 | 1860 | -33.3 | 0.9 |
| Corona_5a 1. | 1941 | 1997 | -0.1 | 0.91 |
| FAST_1 1. | 2185 | 2264 | -18.1 | 7.3 |
| Bromo_TP 1. | 2302 | 2365 | -15.1 | 7.6 |
| DUF2131 1. | 2369 | 2433 | -24.4 | 3.3 |
| TnsA_C 1. | 2455 | 2526 | -12.9 | 7.9 |
| HEAT 9. | 2967 | 3005 | 1.2 | 35 |
3. Sequence Information
Fasta Sequence: XSB2927.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] DEEDILSHSS494-SQISAVPSDP
Ser494 
Ser
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Asp485 | Glu486 | Glu487 | Asp488 | Ile489 | Leu490 | Ser491 | His492 | Ser493 | Ser494 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ser495 | Gln496 | Ile497 | Ser498 | Ala499 | Val500 | Pro501 | Ser502 | Asp503 | Pro504 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
LQPDSVDLTGCDLTSAATDGDEEDILSHSSSQISAVPSDPAMDLNDGTQASSPISDSSQT
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Canis familiaris |
115.00 |
1 |
PREDICTED: similar to Huntingtin (Huntingtons dise |
| 2 |
Sus scrofa |
115.00 |
1 |
huntingtin |
| 3 |
N/A |
114.00 |
6 |
H |
| 4 |
Rattus norvegicus |
114.00 |
1 |
PREDICTED: similar to Huntingtin (Huntington disea |
| 5 |
Mus musculus |
114.00 |
1 |
huntingtin |
| 6 |
Homo sapiens |
111.00 |
6 |
huntingtin |
| 7 |
Macaca mulatta |
111.00 |
1 |
PREDICTED: huntingtin |
| 8 |
Pan troglodytes |
111.00 |
1 |
PREDICTED: huntingtin |
| 9 |
Bos taurus |
110.00 |
1 |
PREDICTED: similar to huntingtin |
| 10 |
Monodelphis domestica |
108.00 |
1 |
PREDICTED: similar to Huntingtons Disease protein |
| 11 |
Gallus gallus |
98.60 |
1 |
PREDICTED: similar to Huntingtons Disease protein |
| 12 |
Xenopus tropicalis |
84.30 |
1 |
huntingtin |
| 13 |
Danio rerio |
34.70 |
1 |
huntingtin |
| 14 |
Drosophila melanogaster |
34.70 |
1 |
Su(var)2-HP2 CG12864-PA, isoform A |
Top-ranked sequences
| organism | matching |
|---|
| Canis familiaris |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
||||||||| ||| ||||||||||||||||#|||||||||||||||||||||||+||||||
Sbjct 495 LQPDSVDLTSCDLASAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPVSDSSQT 554
|
| Sus scrofa |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
||||||||+||||+||||||||||||||||#||+||||||||||||||||||||+||||||
Sbjct 504 LQPDSVDLSGCDLSSAATDGDEEDILSHSS#SQMSAVPSDPAMDLNDGTQASSPVSDSSQT 563
|
| N/A |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
|| |||||+|||||||||||||||||||||#|| |||||||||||||||||||||||||||
Sbjct 476 LQADSVDLSGCDLTSAATDGDEEDILSHSS#SQFSAVPSDPAMDLNDGTQASSPISDSSQT 535
|
| Rattus norvegicus |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
|| |||||+|||||||||||||||||||||#|| |||||||||||||||||||||||||||
Sbjct 485 LQADSVDLSGCDLTSAATDGDEEDILSHSS#SQFSAVPSDPAMDLNDGTQASSPISDSSQT 544
|
| Mus musculus |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
|| |||||+|||||||||||||||||||||#|| |||||||||||||||||||||||||||
Sbjct 485 LQADSVDLSGCDLTSAATDGDEEDILSHSS#SQFSAVPSDPAMDLNDGTQASSPISDSSQT 544
|
| Homo sapiens |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
|| ||||| |||||+||||||||||||||#||+|||||||||||||||||||||||||||
Sbjct 507 LQADSVDLASCDLTSSATDGDEEDILSHSS#SQVSAVPSDPAMDLNDGTQASSPISDSSQT 566
|
| Macaca mulatta |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
|| ||||| |||||+||||||||||||||#||+|||||||||||||||||||||||||||
Sbjct 494 LQADSVDLASCDLTSSATDGDEEDILSHSS#SQVSAVPSDPAMDLNDGTQASSPISDSSQT 553
|
| Pan troglodytes |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
|| ||||| |||||+||||||||||||||#||+|||||||||||||||||||||||||||
Sbjct 507 LQADSVDLASCDLTSSATDGDEEDILSHSS#SQVSAVPSDPAMDLNDGTQASSPISDSSQT 566
|
| Bos taurus |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
|| |+||| ||||||||||||||||||||#||+|||||||||||||||||||||||||||
Sbjct 498 LQTDAVDLAACDLTSAATDGDEEDILSHSS#SQMSAVPSDPAMDLNDGTQASSPISDSSQT 557
|
| Monodelphis domestica |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
|| | |||||||||||||||||||+|| ||#|||||||||||+|+||||||||||||||||
Sbjct 498 LQSDPVDLTGCDLTSAATDGDEEDMLSRSS#SQISAVPSDPAVDMNDGTQASSPISDSSQT 557
|
| Gallus gallus |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQASSPISDSSQT 524
|| |||||+ ||||| ||+|+++|+|| ||#|||||| ||| |||||||||||||||||||
Sbjct 459 LQSDSVDLSSCDLTSTATEGEDDDVLSRSS#SQISAVQSDPTMDLNDGTQASSPISDSSQT 518
|
| Xenopus tropicalis |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDG-TQASSPISDSSQ 523
|| ||||++ || | |+|||||||||||#|||| | || |+||+| ||||||+|||||
Sbjct 436 LQSDSVDISSSDLASTVTEGDEEDILSHSS#SQISTVQSDTNMELNEGTTQASSPVSDSSQ 495
Query 524 T 524
|
Query 524 T 524
|
| Danio rerio |
Query 465 LQP-DSVDLTGCDL---TSAATDGDEEDILSHSS#S---QISAVPSDPAMDLND---GTQA 514
||| |||||+ + + ||||+|| ||#| + + | | | | +
Sbjct 447 LQPGDSVDLSASEQGVGPDTPDEEDEEDMLSRSS#SGGAGLVSTSGDLVTDANQMSAGAVS 506
Query 515 SSPISDSSQT 524
||| |+||||
Sbjct 507 SSPPSESSQT 516
|
| Drosophila melanogaster |
Query 465 LQPDSVDLTGCDLTSAATDGDEEDILSHSS#SQISAVPSDPAMDLNDGTQ-ASSPISDSSQ 523
|+||+ | | | | +| |+ #| + +| ++| |+ | + | ||| +||+
Sbjct 1810 LEPDNAALEE-DTASTAKAAEEMDLYIKEK#SNVKSVLAEPETDVTDDEELAQSPIPNSSE 1868
Query 524 T 524
|
Query 524 T 524
|
