logo CaMPDB: Calpain for Modulatory Proteolysis Database

CL0016 : Chain A, Catalytic Domain Of Human Calpain-9

[ CaMP Format ]

* Basic Information

OrganismHomo sapiens (human)
Protein NamesCalpain-9; 3.4.22.-; Digestive tract-specific calpain; New calpain 4; nCL-4; Protein CG36
Gene NamesNCL4
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
1ZIV_A N/A N/A O14815 N/A N/A N/A hsa:10753

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 339 aa

Average Mass: 38.267 kDa

Monoisotopic Mass: 38.243 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Peptidase_C2 1. 34329642.15.4e-190

3. Sequence Information

Fasta Sequence: CL0016.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1ZIV (X-ray; 231 A; A=26-347), 2P0R (X-ray; 250 A; A/B=10-340)

* References

[PubMed ID: 17157313] Davis TL, Walker JR, Finerty PJ Jr, Mackenzie F, Newman EM, Dhe-Paganon S, The crystal structures of human calpains 1 and 9 imply diverse mechanisms of action and auto-inhibition. J Mol Biol. 2007 Feb 9;366(1):216-29. Epub 2006 Nov 14.