CaMPDB :: Calpain

CL0040 : calcium-dependent protease large subunit

* Basic Information

Organism	Homo sapiens (human)
Protein Names	Calpain-2 catalytic subunit; 3.4.22.53; Calpain-2 large subunit; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; M-calpain; Millimolar-calpain; Calpain large polypeptide L2
Gene Names	CAPN1; CANPL2
Gene Locus	Not available
GO Function	Not available

Entrez Protein	Entrez Nucleotide	Entrez Gene	UniProt	OMIM	HGNC	HPRD	KEGG
AAA52760	N/A	N/A	P17655	N/A	N/A	N/A	hsa:824

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 79 aa

Average Mass: 8.653 kDa

Monoisotopic Mass: 8.647 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain name	begin	end	score	e-value

3. Sequence Information

Fasta Sequence: CL0040.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1KFU (X-ray; 250 A; L=1-700), 1KFX (X-ray; 315 A; L=1-700), 2NQA (X-ray; 220 A; A=43-346)

* References

[PubMed ID: 2539381] Hata A, Ohno S, Akita Y, Suzuki K, Tandemly reiterated negative enhancer-like elements regulate transcription of a human gene for the large subunit of calcium-dependent protease. J Biol Chem. 1989 Apr 15;264(11):6404-11.