CL0116 : calpain-like protease CAPN10a
[ CaMP Format ]
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | calpain-like protease CAPN10a [Homo sapiens]; Calpain-10; 3.4.22.-; Calcium-activated neutral proteinase 10; CANP 10 |
| Gene Names | KIAA1845 |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 672 aa
Average Mass: 74.938 kDa
Monoisotopic Mass: 74.891 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Peptidase_C2 1. | 13 | 316 | 182.5 | 1.2e-51 |
| Calpain_III 1. | 338 | 494 | 31.4 | 1.8e-09 |
| Calpain_III 2. | 513 | 645 | 14.8 | 3.6e-08 |
3. Sequence Information
Fasta Sequence: CL0116.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* References
[PubMed ID: 11017071] Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI, Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet. 2000 Oct;26(2):163-75.