logo CaMPDB: Calpain for Modulatory Proteolysis Database

CL0120 : calpain-like protease CAPN10d

[ CaMP Format ]

* Basic Information

OrganismHomo sapiens (human)
Protein Namescalpain-like protease CAPN10d [Homo sapiens]; Calpain-10; 3.4.22.-; Calcium-activated neutral proteinase 10; CANP 10
Gene NamesKIAA1845
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAG17970 N/A N/A Q9HC96 N/A N/A N/A hsa:11132

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 513 aa

Average Mass: 57.816 kDa

Monoisotopic Mass: 57.779 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Peptidase_C2 1. 13316182.51.2e-51
Calpain_III 1. 33849432.71.4e-09

3. Sequence Information

Fasta Sequence: CL0120.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* References

[PubMed ID: 11017071] Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI, Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet. 2000 Oct;26(2):163-75.