CaMPDB :: Calpain

CL0352 : GC36 [Homo sapiens]

* Basic Information

Organism	Homo sapiens (human)
Protein Names	Calpain-9; 3.4.22.-; Digestive tract-specific calpain; New calpain 4; nCL-4; Protein CG36
Gene Names	GC36; NCL4
Gene Locus	Not available
GO Function	Not available

Entrez Protein	Entrez Nucleotide	Entrez Gene	UniProt	OMIM	HGNC	HPRD	KEGG
BAA92137	N/A	N/A	O14815	N/A	N/A	N/A	hsa:10753

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 664 aa

Average Mass: 76.168 kDa

Monoisotopic Mass: 76.120 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain name	begin	end	score	e-value
Peptidase_C2 1.	42	311	558.7	6.9e-165
Calpain_III 1.	322	468	355.0	1.4e-103
NUC153 1.	494	525	-3.4	3.6
efhand 1.	539	567	27.2	6.9e-05
efhand 2.	569	597	21.6	0.0032

3. Sequence Information

Fasta Sequence: CL0352.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1ZIV (X-ray; 231 A; A=26-347), 2P0R (X-ray; 250 A; A/B=10-340)

* References

[PubMed ID: 10835488] Yoshikawa Y, Mukai H, Hino F, Asada K, Kato I, Isolation of two novel genes, down-regulated in gastric cancer. Jpn J Cancer Res. 2000 May;91(5):459-63.