logo CaMPDB: Calpain for Modulatory Proteolysis Database

CL0851 : skeletal muscle-specific calpain

[ CaMP Format ]

* Basic Information

OrganismOvis aries (sheep)
Protein Namescalpain 3 [Ovis aries]; Calpain-3; 3.4.22.54; Calpain L3; Calpain p94; Calcium-activated neutral proteinase 3; CANP 3; Muscle-specific calcium-activated neutral protease 3; New calpain 1; nCL-1
Gene NamesCAPN3; NCL1; calpain 3, (p94)
Gene Locus7; chromosome 7
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001009212 NM_001009212 443038 Q9TTH8 N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 822 aa

Average Mass: 94.595 kDa

Monoisotopic Mass: 94.535 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Peptidase_C2 1. 74418892.71.9e-265
Calpain_III 1. 429583369.56.1e-108
efhand 1. 6546811.215
efhand 2. 69772528.52.6e-05
efhand 3. 72775527.55.3e-05
efhand 4. 7928199.91.8

3. Sequence Information

Fasta Sequence: CL0851.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* References

[PubMed ID: 17272862] Chung H, Choi B, Jang G, Lee K, Kim H, Yoon S, Im S, Davis M, Hines H, Effect of variants in the ovine skeletal-muscle-specific calpain gene on body weight. J Appl Genet. 2007;48(1):61-8.

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