CL0899 : calpain 5
[ CaMP Format ]
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | calpain 5 [Mus musculus]; Calpain-5; 3.4.22.-; New calpain 3; nCL-3 |
| Gene Names | Capn5; Ncl3; calpain 5 |
| Gene Locus | 7; chromosome 7 |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 640 aa
Average Mass: 72.955 kDa
Monoisotopic Mass: 72.909 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Peptidase_C2 1. | 26 | 343 | 430.6 | 2.4e-126 |
| Calpain_III 1. | 353 | 496 | 295.6 | 1.1e-85 |
| C2 1. | 519 | 596 | 55.2 | 2.4e-13 |
3. Sequence Information
Fasta Sequence: CL0899.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* References
[PubMed ID: 14981075] Gafni J, Hermel E, Young JE, Wellington CL, Hayden MR, Ellerby LM, Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus. J Biol Chem. 2004 May 7;279(19):20211-20. Epub 2004 Feb 23.