CL0941 : calpain 8
[ CaMP Format ]
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | stomach-specific calpain (nCL-2); calpain 8 [Mus musculus]; Calpain-8; 3.4.22.53; Stomach-specific M-type calpain; New calpain 2; nCL-2 |
| Gene Names | Capn8; Ncl2; calpain 8 |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| NP_570960 | NM_130890 | 170725 | Q91VA3 | N/A | N/A | N/A | mmu:170725 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 703 aa
Average Mass: 79.335 kDa
Monoisotopic Mass: 79.285 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Peptidase_C2 1. | 45 | 344 | 725.5 | 4.1e-215 |
| Calpain_III 1. | 355 | 512 | 360.1 | 4.1e-105 |
| efhand 1. | 579 | 607 | 14.4 | 0.49 |
| efhand 2. | 609 | 637 | 13.2 | 0.77 |
| efhand 3. | 674 | 701 | 5.2 | 5.7 |
3. Sequence Information
Fasta Sequence: CL0941.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* References
[PubMed ID: 17646163] Hata S, Doi N, Kitamura F, Sorimachi H, Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains. J Biol Chem. 2007 Sep 21;282(38):27847-56. Epub 2007 Jul 23.