CL0946 : calpain 12
[ CaMP Format ]
* Basic Information
Organism | Homo sapiens (human) |
Protein Names | calpain 12 [Homo sapiens]; Calpain-12; 3.4.22.- |
Gene Names | CAPN12; calpain 12 |
Gene Locus | 19q13.2; chromosome 19 |
GO Function | Not available |
* Information From OMIM
Description: Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000). CAPN12 belongs to the calpain large subunit family.
* Structure Information
1. Primary Information
Length: 719 aa
Average Mass: 81.037 kDa
Monoisotopic Mass: 80.985 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
domain name | begin | end | score | e-value |
---|---|---|---|---|
PsbJ 1. | 1 | 39 | 3.1 | 5.5 |
Peptidase_C2 1. | 45 | 341 | 511.1 | 1.4e-150 |
Calpain_III 1. | 353 | 528 | 133.0 | 9.6e-37 |
efhand 1. | 624 | 652 | 21.5 | 0.0035 |
3. Sequence Information
Fasta Sequence: CL0946.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* References
[PubMed ID: 10964513] Dear TN, Meier NT, Hunn M, Boehm T, Gene structure, chromosomal localization, and expression pattern of Capn12, a new member of the calpain large subunit gene family. Genomics. 2000 Sep 1;68(2):152-60.