logo CaMPDB: Calpain for Modulatory Proteolysis Database

CL0951 : calpain 3

[ CaMP Format ]

* Basic Information

OrganismBos taurus (cattle)
Protein Namesskeletal muscle-specific calpain; calpain 3 [Bos taurus]; Calpain-3; 3.4.22.54; Calpain L3; Calpain p94; Calcium-activated neutral proteinase 3; CANP 3; Muscle-specific calcium-activated neutral protease 3; New calpain 1; nCL-1
Gene NamesCAPN3; NCL1; calpain 3, (p94)
Gene Locus10; chromosome 10
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_776685 NM_174260 281663 P51186 N/A N/A N/A bta:281663

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 822 aa

Average Mass: 94.603 kDa

Monoisotopic Mass: 94.543 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Peptidase_C2 1. 74418897.66.3e-267
Calpain_III 1. 429583369.56.1e-108
efhand 1. 6546811.215
efhand 2. 69772528.52.6e-05
efhand 3. 72775529.31.5e-05
efhand 4. 7928199.91.8

3. Sequence Information

Fasta Sequence: CL0951.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* References

[PubMed ID: 18590576] Barendse W, Harrison BE, Bunch RJ, Thomas MB, Variation at the Calpain 3 gene is associated with meat tenderness in zebu and composite breeds of cattle. BMC Genet. 2008 Jul 1;9:41.

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