logo CaMPDB: Calpain for Modulatory Proteolysis Database

CL0973 : Calpain-2 catalytic subunit

[ CaMP Format ]

* Basic Information

OrganismMus musculus (house mouse)
Protein NamesCalpain-2 large subunit; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; M-calpain; Millimolar-calpain; 80 kDa M-calpain subunit; CALP80; 3.4.22.53
Gene NamesCapn2
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
O08529 N/A N/A O08529 N/A N/A N/A mmu:12334

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 700 aa

Average Mass: 79.872 kDa

Monoisotopic Mass: 79.822 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Peptidase_C2 1. 45344810.88.5e-241
Calpain_III 1. 355510384.71.6e-112
efhand 1. 57660420.40.0074
efhand 2. 60663419.40.015
efhand 3. 6716981.813

3. Sequence Information

Fasta Sequence: CL0973.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* References

[PubMed ID: 9339374] Dear N, Matena K, Vingron M, Boehm T, A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution. Genomics. 1997 Oct 1;45(1):175-84.

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