XSB0026 : PREDICTED: similar to glucagon preproprotein [Macaca mulatta]
[ CaMP Format ]
This entry is computationally expanded from SB0054
* Basic Information
| Organism | Macaca mulatta (rhesus monkey) |
| Protein Names | similar to glucagon preproprotein |
| Gene Names | LOC705508; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 3 mRNAs, 3204 ESTs |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| XP_001093871 | XM_001093871 | 705508 | N/A | N/A | N/A | N/A | N/A |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 263 aa
Average Mass: 30.431 kDa
Monoisotopic Mass: 30.412 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| DM 1. | 23 | 71 | -21.7 | 8 |
| Hormone_2 1. | 136 | 163 | 66.4 | 1.1e-16 |
| --- cleavage 150 (inside Hormone_2 136..163) --- | ||||
| --- cleavage 152 (inside Hormone_2 136..163) --- | ||||
| --- cleavage 160 (inside Hormone_2 136..163) --- | ||||
| --- cleavage 162 (inside Hormone_2 136..163) --- | ||||
| --- cleavage 157 (inside Hormone_2 136..163) --- | ||||
| Hormone_2 2. | 181 | 208 | 52.6 | 1.5e-12 |
| Hormone_2 3. | 229 | 256 | 45.3 | 2.4e-10 |
3. Sequence Information
Fasta Sequence: XSB0026.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
5 [sites]
Cleavage sites (±10aa)
[Site 1] FTSDYSKYLD150-SRRAQDFVQW
Asp150 
Ser
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Phe141 | Thr142 | Ser143 | Asp144 | Tyr145 | Ser146 | Lys147 | Tyr148 | Leu149 | Asp150 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser151 | Arg152 | Arg153 | Ala154 | Gln155 | Asp156 | Phe157 | Val158 | Gln159 | Trp160 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| TDPLGDPDQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFER |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 126.00 | 9 | glucagon, isoform CRA_b |
| 2 | Pan troglodytes | 103.00 | 2 | PREDICTED: fibroblast activation protein, alpha su |
| 3 | N/A | 79.70 | 43 | 0 |
| 4 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 64.70 | 1 | AAB31092.1 |
| 5 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 61.60 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
| 6 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 60.80 | 1 | glucagon II |
| 7 | Contains: Glucagon; Glucagon-like peptide | 60.10 | 4 | GLUC_AMICA Glucagon precursor |
| 8 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 60.10 | 1 | glucagon |
| 9 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 58.50 | 1 | glucagon G-29 |
| 10 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 57.80 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gb |
| 11 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.20 | 1 | GLUC_LAMFL Glucagon gb |
| 12 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 53.50 | 1 | glucagon |
| 13 | deshis1, Desphe6, Glu9 | 53.50 | 1 | A Chain A, Nmr Solution Structure Of The Glucagon |
| 14 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 47.00 | 1 | GLUC1_PETMA Glucagon-1 precursor |
| 15 | Gallus gallus | 44.30 | 4 | glucagon isoform 1 |
| 16 | Meleagris gallopavo | 44.30 | 2 | preproglucagon B |
| 17 | Agkistrodon piscivorus | 44.30 | 1 | proglucagon |
| 18 | Capra hircus | 43.90 | 1 | glucagon |
| 19 | Oncorhynchus tshawytscha | 43.50 | 1 | S78474_1 proglucagon |
| 20 | Monodelphis domestica | 42.70 | 3 | PREDICTED: similar to Gastric inhibitory polypepti |
| 21 | Xenopus laevis | 42.40 | 5 | proglucagon I |
| 22 | Rattus norvegicus | 42.40 | 3 | Glucose-dependent insulinotropic peptide |
| 23 | Xenopus tropicalis | 42.40 | 2 | glucagon |
| 24 | Canis familiaris | 42.40 | 2 | PREDICTED: similar to Gastric inhibitory polypepti |
| 25 | Danio rerio | 42.00 | 4 | hypothetical protein LOC494052 |
| 26 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | 42.00 | 1 | GLUC_HELSU Glucagon precursor |
| 27 | Heloderma suspectum | 41.60 | 2 | proglucagon |
| 28 | Hoplobatrachus rugulosus | 41.60 | 1 | AF324209_1 proglucagon |
| 29 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 41.20 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
| 30 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 41.20 | 1 | glucagon-like peptide, GLP |
| 31 | Bos taurus | 40.40 | 5 | PREDICTED: similar to Gastric inhibitory polypepti |
| 32 | Macaca mulatta | 40.40 | 3 | PREDICTED: gastric inhibitory polypeptide |
| 33 | Ictalurus punctatus | 40.40 | 3 | proglucagon I |
| 34 | Sebastes caurinus | 40.00 | 4 | proglucagon II |
| 35 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 40.00 | 2 | GLUC_CARAU Glucagon precursor |
| 36 | Tetraodon nigroviridis | 40.00 | 2 | unnamed protein product |
| 37 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
| 38 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
| 39 | Heloderma horridum | 40.00 | 1 | EXE3_HELHO Exendin-3 precursor emb |
| 40 | Mus musculus | 39.30 | 5 | Gastric inhibitory polypeptide |
| 41 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 38.90 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
| 42 | Protopterus dolloi | 38.90 | 1 | proglucagon |
| 43 | Bufo marinus | 38.90 | 1 | proglucagon |
| 44 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 38.10 | 1 | GLUC2_PETMA Glucagon-2 precursor |
| 45 | Neoceratodus forsteri | 38.10 | 1 | proglucagon |
| 46 | synthetic construct | 37.00 | 1 | Homo sapiens glucagon |
| 47 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 36.60 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
| 48 | Phodopus sungorus | 36.60 | 1 | glucagon precursor |
| 49 | Sus scrofa | 36.20 | 1 | glucagon |
| 50 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 35.80 | 1 | GLUC_LEPSP Glucagon precursor |
| 51 | Canis lupus familiaris | 35.80 | 1 | glucagon |
| 52 | Hydrolagus colliei | 35.40 | 1 | proglucagon |
| 53 | Squalus acanthias | 35.40 | 1 | proglucagon |
| 54 | Heloderma suspectum, venom, Peptide, 39 aa | 35.40 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30-V |
| 55 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 34.70 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
| 56 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 34.70 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gb |
| 57 | swine, intestines, Peptide Partial, 56 aa | 32.30 | 1 | secretin precursor, N-prosecretin, secretin-(-9 to |
| 58 | Ambloplites rupestris | 32.30 | 1 | proglucagon |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 122 DPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 ||| |||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 122 DPLSDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 |
| Pan troglodytes | Query 122 DPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 177 ||| |||||||||||||||||||||||||#||||||||||||||||| +++| || | Sbjct 961 DPLSDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN-SSVAYRHAE 1015 |
| N/A | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIA 172 |||||||||||||||#|||||||||||||||||+|||| Sbjct 1 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNKNNIA 37 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN 167 ||+||||||||||+|#+|||+|||||||+|||| Sbjct 1 HSEGTFTSDYSKYMD#NRRAKDFVQWLMSTKRN 32 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 164 |||||||||||||||#+||||||+||||+| Sbjct 1 HSQGTFTSDYSKYLD#NRRAQDFIQWLMST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN 167 ||+|||++||||||+#+|||||||||| |+||| Sbjct 1 HSEGTFSNDYSKYLE#TRRAQDFVQWLKNSKRN 32 |
| Contains: Glucagon; Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 164 |||||||+|||||+|#+|||||||||||+| Sbjct 1 HSQGTFTNDYSKYMD#TRRAQDFVQWLMST 29 |
| Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 164 |||||||+|||||+|#+|||||||||||+| Sbjct 1 HSQGTFTNDYSKYMD#TRRAQDFVQWLMST 29 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 164 ||+||||||||||+|#+|||+|||||||+| Sbjct 1 HSEGTFTSDYSKYMD#NRRAKDFVQWLMST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN 167 ||+|||++||||||+# |+|||||+|||| ||+ Sbjct 1 HSEGTFSNDYSKYLE#DRKAQDFVRWLMNNKRS 32 |
| Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 164 ||||+||||||||||#|++|+||| ||||| Sbjct 1 HSQGSFTSDYSKYLD#SKQAKDFVIWLMNT 29 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMN 163 ||+|||||||||||+#+++|+|||+|||| Sbjct 1 HSEGTFTSDYSKYLE#NKQAKDFVRWLMN 28 |
| deshis1, Desphe6, Glu9 | Query 137 SQGTFTSDYSKYLD#SRRAQDFVQWLMNT 164 |||| ||+||||||#|||||||||||||| Sbjct 1 SQGT-TSEYSKYLD#SRRAQDFVQWLMNT 27 |
| Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 ||||+|||||||||||+#+++|+|||+|||| || + + +|| Sbjct 41 KRHSEGTFTSDYSKYLE#NKQAKDFVRWLMNAKRGGSELQRRH 82 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR---------NNIAKRHDE 177 +||+ ||||+| + |||#++ |+||| || + ++| |+ ||| | Sbjct 80 RRHADGTFTNDMTSYLD#AKAARDFVSWLARSDKSRRDGGDHLAENSEDKRHAE 132 |
| Gallus gallus | Query 121 TDPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN------------- 167 ++|| + |+|| |||||||||||||||||#||||||||||||+|||| Sbjct 40 SEPLDESRQLNEVKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMSTKRNGQQGQEDKENDKF 99 Query 168 -----RNNIAKRHDEFER 180 | |+||| |||| Sbjct 100 PDQLSSNAISKRHSEFER 117 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNI 171 +||+ |||||| +| ||# |++|++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILD#DMAAKEFLKWLINTKVTQRDL 201 Query 131 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 +| +||++||+||| + ||+# + |++|+ ||+| + |+ Sbjct 113 SEFERHAEGTYTSDITSYLE#GQAAKEFIAWLVNGRGRRD 151 |
| Meleagris gallopavo | Query 121 TDPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN------------- 167 ++|| + |+|| |||||||||||||||||#||||||||||||+|||| Sbjct 40 SEPLDESRQLNEVKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMSTKRNGQQGQEDKENDEF 99 Query 168 -----RNNIAKRHDEFER 180 | |+||| |||| Sbjct 100 PDQLSSNAISKRHSEFER 117 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNI 171 +||+ |||||| +| ||# |++|++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILD#DMAAKEFLKWLINTKVTQRDL 201 Query 131 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 +| +||++||+||| + ||+# + |++|+ ||+| + |+ Sbjct 113 SEFERHAEGTYTSDITSYLE#GQAAKEFIAWLVNGRGRRD 151 |
| Agkistrodon piscivorus | Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNI 171 +||+ |||||||+| ||# |+|++||+| | + ++ Sbjct 82 RRHADGTFTSDYNKLLD#DIATQEFLKWLINQKVTQRDL 119 Query 132 EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 | +||+ ||+||| | ||+# + |++|+ ||+| + |+ Sbjct 32 EYERHADGTYTSDISSYLE#GQAAKEFIAWLVNGRGRRD 69 |
| Capra hircus | Query 131 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 168 +| +||++|||||| | ||+# + |++|+ ||+ + | Sbjct 8 DEFERHAEGTFTSDVSSYLE#GQAAKEFIAWLVKGRGRR 45 |
| Oncorhynchus tshawytscha | Query 137 SQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 | |||++||||| +# | ||||||||||+||+ +||| Sbjct 2 SXGTFSNDYSKYQE#ERMAQDFVQWLMNSKRS-GAPSKRH 39 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 168 |||+ ||+||| | || # + |+||| || + + | Sbjct 37 KRHADGTYTSDVSTYLQ#DQAAKDFVSWLKSGRARR 71 |
| Monodelphis domestica | Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 +|+++||| |||| +|# |||| ||++ | +| + ||+ || Sbjct 51 QRYAEGTFISDYSITMD#KIMQQDFVNWLLSQKGKKN--SWRHNITER 95 |
| Xenopus laevis | Query 122 DPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 + + | +|+ | |||||||||||||||||#||||||||||||||||+ +++|+ ++|| Sbjct 39 EAVDDSEQLKEVKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRS-GELSRRNADYER 96 Query 125 GDPDQMNED-KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 |+ + | | +||++|||||| ++ ||# + |++|+ ||+| ++ |++|+ |||| Sbjct 85 GELSRRNADYERHAEGTFTSDVTQQLD#EKAAKEFIDWLINGGPSKEIISRRNAEFER 141 Query 133 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNI 171 |+||+ |+||+| +| ||# ||+|+ |++||+ ++ Sbjct 224 DRRHADGSFTNDINKVLD#IIAAQEFLDWVINTQETERDL 262 Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 ||++||||+| + ||+# + |++|| ||+ + || Sbjct 179 RHAEGTFTNDMTNYLE#EKAAKEFVGWLIKGRPKRN 213 Query 132 EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 177 | +||++||+|+| ++||+# + |++|++||+ | + + || | Sbjct 138 EFERHAEGTYTNDVTEYLE#EKAAKEFIEWLIKGKPKKIRYS-RHAE 182 |
| Rattus norvegicus | Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNN 170 |+++||| |||| +|# | |||| ||+ | +|+ Sbjct 43 RYAEGTFISDYSIAMD#KIRQQDFVNWLLAQKGKKND 78 |
| Xenopus tropicalis | Query 122 DPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 + + | |+ | |||||||||||||||||#|||||||+||||||||+ +++|+ ++|| Sbjct 39 EAVDDSQQLKEVKRHSQGTFTSDYSKYLD#SRRAQDFIQWLMNTKRS-GGLSRRNADYER 96 Query 125 GDPDQMNED-KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 | + | | +||++|||||| +++||# + |++|+ ||+| ++ |++|+ + || Sbjct 85 GGLSRRNADYERHAEGTFTSDVTQHLD#EKAAKEFIDWLINGGPSKEIISRRNADVER 141 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 177 +||++||+|+| ++||+# + |++|++||+| | + + || | Sbjct 140 ERHAEGTYTNDVTEYLE#EKAAKEFIEWLINGKPKKIRYS-RHAE 182 Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 ||++||||+| + ||+# + |++|| ||+ + || Sbjct 179 RHAEGTFTNDMTNYLE#EKAAKEFVGWLIKGRPKRN 213 Query 133 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 165 |+||+ |+||+| +| ||# ||+|+ |++||+ Sbjct 224 DRRHADGSFTNDINKVLD#IIAAQEFLDWVINTQ 256 |
| Canis familiaris | Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNN 170 |+++||| |||| +|# | |||| ||+ | +|+ Sbjct 43 RYAEGTFISDYSIAMD#KIRQQDFVNWLLAQKGKKND 78 |
| Danio rerio | Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 177 ||||+|||++||||||+#+|||||||||||| ||| ++ ||| | Sbjct 48 KRHSEGTFSNDYSKYLE#TRRAQDFVQWLMNAKRNGGSV-KRHAE 90 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWL 161 |||++||+||| | || # + || || || Sbjct 86 KRHAEGTYTSDVSSYLQ#DQAAQSFVAWL 113 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | Query 122 DPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKR--------------- 166 +|| | |+|| |||||||||||||||||#+||||||||||||||| Sbjct 39 EPLDDSRQLNEVKRHSQGTFTSDYSKYLD#TRRAQDFVQWLMNTKRSGQQGVEEREKENLL 98 Query 167 ---NRNNIAKRHDEFER 180 + | +|+ | |+|| Sbjct 99 DQLSSNGLARHHAEYER 115 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNI 171 +||+ |||||||++ ||# |+|++||+| | + ++ Sbjct 162 RRHADGTFTSDYNQLLD#DIATQEFLKWLINQKVTQRDL 199 Query 132 EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 | +||+ | +||| | ||+# + |++|+ ||+| + |+ Sbjct 112 EYERHADGRYTSDISSYLE#GQAAKEFIAWLVNGRGRRD 149 |
| Heloderma suspectum | Query 122 DPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKR--------------- 166 +|| | |+|| |||||||||||||||||#+||||||||||||||| Sbjct 39 EPLDDSRQLNEVKRHSQGTFTSDYSKYLD#TRRAQDFVQWLMNTKRSGQQGVEEREKENLL 98 Query 167 ---NRNNIAKRHDEFER 180 + | +|+ | |+|| Sbjct 99 DQLSSNGLARHHAEYER 115 Query 132 EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 168 | +||+ | +||| | ||+# + |++|+ ||+| + | Sbjct 112 EYERHADGRYTSDISSYLE#GQAAKEFIAWLVNGRGRR 148 |
| Hoplobatrachus rugulosus | Query 121 TDPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 |+ | | | || |||||||||||||||||#|||||||||||||+||+ |+||+ +||| Sbjct 38 TEALDDSDHHNEVKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNSKRS-GGISKRNVQFER 96 Query 133 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 164 |+||+ |+||||++| ||# + ||+|+ |++|| Sbjct 178 DRRHADGSFTSDFNKALD#IKAAQEFLDWIINT 209 Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 ||++|||||| + ||+# + |++|| ||+ + || Sbjct 134 RHAEGTFTSDMTSYLE#EKAAKEFVDWLIKGRPKRN 168 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 177 +||++||+|+| +++|+# + |++|+ ||+ | + ++ || | Sbjct 95 ERHAEGTYTNDVTQFLE#EKAAKEFIDWLIKGKPKKQRLS-RHAE 137 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 124 LGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 | +| + ||||+|||++||||||+#+|||||||||| |+| || + +|| Sbjct 40 LTEPIEPLNMKRHSEGTFSNDYSKYLE#TRRAQDFVQWLKNSK--RNGLFRRH 89 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWL 161 +||+ ||+||| | || # + |+||| || Sbjct 87 RRHADGTYTSDVSSYLQ#DQAAKDFVSWL 114 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN 167 |+ ||||+| + |||#++ |+||| || + ++ Sbjct 1 HADGTFTNDMTSYLD#AKAARDFVSWLARSDKS 32 |
| Bos taurus | Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNN 170 |+++||| |||| +|# | |||| ||+ | +++ Sbjct 81 RYAEGTFISDYSIAMD#KIRQQDFVNWLLAQKGKKSD 116 |
| Macaca mulatta | Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNN 170 |+++||| |||| +|# |||| ||+ | +|+ Sbjct 51 RYAEGTFISDYSIAMD#KIHQQDFVNWLLAQKGKKND 86 |
| Ictalurus punctatus | Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 +|||+|||++||||||+#+||||||||||||+||+ ++ |+|| Sbjct 49 RRHSEGTFSNDYSKYLE#TRRAQDFVQWLMNSKRS-DSPARRH 89 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 +|| |+|||| +| ||#| |++++||+||+ + + ||| Sbjct 134 RRHVDGSFTSDVNKVLD#SLAAKEYLQWVMNSPSSAS--GKRH 173 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWL 161 +||+ ||+||| | || # + |+||+ || Sbjct 87 RRHADGTYTSDVSSYLQ#DQAAKDFITWL 114 |
| Sebastes caurinus | Query 124 LGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 | +| ++ ||||+|||++||||||+#+|||||||||| |+||| ++ +|| Sbjct 40 LAEPIELPNMKRHSEGTFSNDYSKYLE#TRRAQDFVQWLKNSKRN-GSLFRRH 90 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 168 +||+ ||+||| | || # + |++|| || + | Sbjct 88 RRHADGTYTSDVSSYLQ#DQAAKEFVYWLKTGRGRR 122 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 177 ||||+|||++||||||+#+|||||||+||||+| | + |||| | Sbjct 48 KRHSEGTFSNDYSKYLE#TRRAQDFVEWLMNSKSNGGS-AKRHAE 90 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWL 161 |||++||+||| | +| # + ||+|| || Sbjct 86 KRHAEGTYTSDISSFLR#DQAAQNFVAWL 113 |
| Tetraodon nigroviridis | Query 124 LGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 | +| ++ ||||+|||++||||||+#+|||||||||| |+||| ++ +|| Sbjct 777 LTEPSDLSNMKRHSEGTFSNDYSKYLE#TRRAQDFVQWLKNSKRN-GSLFRRH 827 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 168 +||+ ||+||| | || # + |++|| || + | Sbjct 825 RRHADGTYTSDVSAYLQ#DQAAKEFVSWLKTGRGRR 859 |
| Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 || |+|||++ |||| +# | |+||+ ||||+||+ +||| Sbjct 50 KRQSEGTFSNYYSKYQE#ERMARDFLHWLMNSKRS-GAPSKRH 90 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNN 170 |||+ ||+||| | || # + |+||| || + | + Sbjct 88 KRHADGTYTSDVSTYLQ#DQAAKDFVSWLKSGPARRES 124 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHD 176 +|| |+|||| +| ||#| |++++ |+| +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLD#SLAAKEYLLWVMTSKTSGKSNKRQED 177 |
| Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 121 TDPL-GDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 |||| | ++ ||||+|||++||||| +# | ||||||||||+||+ +||| Sbjct 36 TDPLLEDLMGVSNVKRHSEGTFSNDYSKYQE#ERMAQDFVQWLMNSKRS-GAPSKRH 90 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNN 170 |||+ ||+||| | || # + |+||| || + + | + Sbjct 88 KRHADGTYTSDVSTYLQ#DQAAKDFVSWLKSGRARRES 124 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHD 176 +|| |+|||| +| ||#| |++++ |+| +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLD#SLAAKEYLLWVMTSKTSGKSNKRQED 177 |
| Heloderma horridum | Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMN 163 |||| |||||| || ++# + |++|| | Sbjct 46 KRHSDGTFTSDLSKQME#EEAVRLFIEWLKN 75 |
| Mus musculus | Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNN 170 |+++||| |||| +|# | |||| ||+ + +++ Sbjct 43 RYAEGTFISDYSIAMD#KIRQQDFVNWLLAQRGKKSD 78 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 165 |+ |+|||| +| ||#+ |++|+ ||++|| Sbjct 1 HADGSFTSDINKVLD#TIAAKEFLNWLISTK 30 |
| Protopterus dolloi | Query 132 EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 | |||||||| |||+| |+#++ | | || ||+||| ++|||+| || Sbjct 28 EAKRHSQGTFMSDYAKLLE#AKHALDLVQRLMSTKRT-GAVSKRHNEIER 75 Query 131 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 || +||++||+||| | ||+# + +|++||| + |+ +| +| Sbjct 71 NEIERHAEGTYTSDISSYLE#GQAVNEFIRWLMKGRGRRDFSETDIEEMDR 120 Query 133 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 165 |+||+ || ||| + |+#| ++|+ ||+| | Sbjct 119 DRRHADGTVTSDINSVLE#SIATREFLNWLINAK 151 |
| Bufo marinus | Query 133 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNT 164 |+||+ |+||||++| ||# + ||+|+ |++|| Sbjct 107 DRRHADGSFTSDFNKALD#IKAAQEFLDWIINT 138 Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 ||++|||||| + +|+# + |++|| ||+ + || Sbjct 62 RHAEGTFTSDMTSFLE#EKAAKEFVDWLIKGRPKRN 96 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDE 177 +||++||+|+| +++|+# + |++|+ ||+ + ++ || | Sbjct 23 ERHAEGTYTNDVTQFLE#EKAAKEFIDWLLKGIPKKQRLS-RHAE 65 |
| Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN------RNNIAKRHDE 177 |||||+|||||||+||# ++|+||| ||+|||| |+ ||| + Sbjct 43 RHSQGSFTSDYSKHLD#VKQAKDFVTWLLNTKRRGVDAQAGANLEKRHSD 91 Query 131 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKR 166 | +|||| |+||+| + ||# |++|++|| | Sbjct 84 NLEKRHSDGSFTNDMNVMLD#RMSAKNFLEWLKQQGR 119 |
| Neoceratodus forsteri | Query 122 DPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 +|+ + | |||||||| |||+| |+#+| | |||| ||||||| ++||| | || Sbjct 10 EPVDASREHTEAKRHSQGTFMSDYAKLLE#ARHALDFVQRLMNTKRN-GGVSKRHSEIER 67 Query 131 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 +| +||++||+||| | ||+# + | +||+||+ + |+ Sbjct 63 SEIERHAEGTYTSDISSYLE#GQAANEFVRWLLKGRGRRD 101 Query 126 DPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 165 | | +||+ || |+| + |+#| ++|+ ||+|+| Sbjct 104 DTDAEEMGRRHADGTITNDMNNVLE#SIATREFLNWLINSK 143 |
| synthetic construct | Query 122 DPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 ||| |||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 39 DPLSDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 97 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 165 +||+ |+|+ + + ||#+ |+||+ ||+ || Sbjct 144 RRHADGSFSDEMNTILD#NLAARDFINWLIQTK 175 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 126 DPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 +| +++ ||||+|||++||||||+# |+||+||+|||| ||+ ||| Sbjct 43 EPRELSNMKRHSEGTFSNDYSKYLE#DRKAQEFVRWLMNNKRS-GVAEKRH 91 Query 133 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWL 161 +|||+ |||||| | || # + +||| | Sbjct 88 EKRHADGTFTSDVSSYLK#DQAIKDFVDRL 116 |
| Phodopus sungorus | Query 139 GTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 |||||| | ||+# + |++|+ ||+ + |+ Sbjct 1 GTFTSDVSSYLE#GQAAKEFIAWLVKGRGRRD 31 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 165 +||+ |+|+ + + ||#| +||+ ||+ || Sbjct 44 RRHADGSFSDEMNTILD#SLATRDFINWLIQTK 75 |
| Sus scrofa | Query 121 TDPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 |||| ||||| |||||||||||||||||||#|||||||||||||||||+|||||||||||| Sbjct 38 TDPLDDPDQMTEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNKNNIAKRHDEFER 97 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 165 +||+ |+|+ + + ||#+ +||+ ||++|| Sbjct 144 RRHADGSFSDEMNTVLD#NLATRDFINWLLHTK 175 |
| Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRN 167 |||||||+|||||||#+|||||||||||+|||+ Sbjct 1 HSQGTFTNDYSKYLD#TRRAQDFVQWLMSTKRS 32 Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 168 |+ ||+||| | || # + |+ || || + | Sbjct 45 HADGTYTSDVSSYLQ#DQAAKKFVTWLKQGQDRR 77 |
| Canis lupus familiaris | Query 121 TDPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFER 180 |+|| | |||||||||||||||||||||||#|||||||||||||||||+|||||||||||| Sbjct 38 TEPLNDLDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNKNNIAKRHDEFER 97 Query 134 KRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTK 165 +||+ |+|+ + + ||#+ +||+ ||+ || Sbjct 144 RRHADGSFSDEMNTVLD#TLATRDFINWLLQTK 175 |
| Hydrolagus colliei | Query 122 DPLGDPDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNI--AKRH 175 + + +| + + |||+ | |+||||||||#+|| +||||||++|||| | ||| Sbjct 18 ESVSNPSTVTDVKRHTDGIFSSDYSKYLD#NRRTKDFVQWLLSTKRNGANTDKTKRH 73 Query 131 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNN--IAKRHDEFER 180 ++ |||+ | +||| + |# +++ ||+ | | + +|+ ++||| | | Sbjct 68 DKTKRHADGIYTSDVASLTD#YLKSKRFVESLSNYNKRQNDRRMSKRHVEGAR 119 Query 132 EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFE 179 | | ++ + +|+| ||+#++ |+||+ ||+ + | + |+ | | Sbjct 116 EGARRTEEDYPNDFSSYLE#AKAAKDFIDWLIK-GQGRRDFAEESREIE 162 |
| Squalus acanthias | Query 127 PDQMNEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRHDEFE 179 |++| |+||+ |||||+ + ||#+ |++|+ |++|+| | | | | Sbjct 118 PEEM--DRRHADGTFTSEINIVLD#TIAAKEFLNWILNSK----TIQSRDSEIE 164 Query 150 D#SRRAQDFVQWLMNTKRNRNNIAKRHDE 177 |#+|||+|||||||+|||| + ||| | Sbjct 1 D#NRRAKDFVQWLMSTKRNGDK-TKRHAE 27 Query 131 NEDKRHSQGTFTSDYSKYLD#SRRAQDFVQWL--MNTKRNRNNIAKRHDEFER 180 ++ |||++||+||| |# +|+ || | | ++| +|+||| | | Sbjct 20 DKTKRHAEGTYTSDVDSLSD#YFKAKRFVDSLTSYNKRQNGRSISKRHVESTR 71 Query 132 EDKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 168 | ||++|++ | | ||+#++ |+||+ ||+ + | Sbjct 68 ESTRHTEGSYR-DISSYLE#AKAAKDFINWLIKGRGRR 103 |
| Heloderma suspectum, venom, Peptide, 39 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMN 163 | +|||||| || ++# + |++|| | Sbjct 1 HGEGTFTSDLSKQME#EEAVRLFIEWLKN 28 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNR 168 |+ || ||| | +|+# + ++|+ ||++ + | Sbjct 1 HADGTLTSDISSFLE#KQATKEFIAWLVSGRGRR 33 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 139 GTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRN 169 ||+||| | || # + |++|| || + |+ Sbjct 3 GTYTSDVSSYLQ#DQAAKEFVSWLKTGRGRRD 33 |
| swine, intestines, Peptide Partial, 56 aa | Query 135 RHSQGTFTSDYSKYLD#SRRAQDFVQWLM 162 ||| |||||+ |+ |#| | | +| |+ Sbjct 29 RHSDGTFTSELSRLRD#SARLQRLLQGLV 56 |
| Ambloplites rupestris | Query 136 HSQGTFTSDYSKYLD#SRRAQDFVQWLMNTKRNRNNIAKRH 175 |||||||+||+ ||+# |+||||++|||| ||+ ||| Sbjct 1 HSQGTFTNDYTNYLE#DRQAQDFIRWLMNNKRS-GAAEKRH 39 Query 133 DKRHSQGTFTSDYSKYLD#SRRAQDFVQWLMN--------TKRNRNNIAKRHDE 177 +|||+ |||| | | # + +||| | + | | | ++|| | Sbjct 36 EKRHADGTFTDDASSDFY#DQAIKDFVAKLKSGQDRREPETDRRREAFSRRHVE 88 |
[Site 2] SDYSKYLDSR152-RAQDFVQWLM
Arg152 Arg
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ser143 | Asp144 | Tyr145 | Ser146 | Lys147 | Tyr148 | Leu149 | Asp150 | Ser151 | Arg152 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Arg153 | Ala154 | Gln155 | Asp156 | Phe157 | Val158 | Gln159 | Trp160 | Leu161 | Met162 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| PLGDPDQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHA |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 128.00 | 10 | glucagon, isoform CRA_b |
| 2 | Pan troglodytes | 101.00 | 2 | PREDICTED: fibroblast activation protein, alpha su |
| 3 | N/A | 79.70 | 44 | 0 |
| 4 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 64.70 | 1 | AAB31092.1 |
| 5 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 61.60 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
| 6 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 60.80 | 1 | glucagon II |
| 7 | Contains: Glucagon; Glucagon-like peptide | 60.10 | 4 | GLUC_AMICA Glucagon precursor |
| 8 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 60.10 | 1 | glucagon |
| 9 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 58.50 | 1 | glucagon G-29 |
| 10 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 57.80 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gb |
| 11 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.20 | 1 | GLUC_LAMFL Glucagon gb |
| 12 | deshis1, Desphe6, Glu9 | 53.50 | 1 | A Chain A, Nmr Solution Structure Of The Glucagon |
| 13 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 53.50 | 1 | glucagon |
| 14 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 47.00 | 1 | GLUC1_PETMA Glucagon-1 precursor |
| 15 | Agkistrodon piscivorus | 45.10 | 1 | proglucagon |
| 16 | Gallus gallus | 44.30 | 4 | glucagon isoform 1 |
| 17 | Meleagris gallopavo | 44.30 | 2 | preproglucagon B |
| 18 | Monodelphis domestica | 43.90 | 3 | PREDICTED: similar to Gastric inhibitory polypepti |
| 19 | Oncorhynchus tshawytscha | 43.50 | 1 | S78474_1 proglucagon |
| 20 | Rattus norvegicus | 42.70 | 5 | Glucose-dependent insulinotropic peptide |
| 21 | Canis familiaris | 42.70 | 2 | PREDICTED: similar to Gastric inhibitory polypepti |
| 22 | Xenopus laevis | 42.40 | 5 | proglucagon I |
| 23 | Xenopus tropicalis | 42.40 | 2 | glucagon |
| 24 | Danio rerio | 42.00 | 4 | hypothetical protein LOC494052 |
| 25 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | 42.00 | 1 | GLUC_HELSU Glucagon precursor |
| 26 | Heloderma suspectum | 41.60 | 2 | proglucagon |
| 27 | Hoplobatrachus rugulosus | 41.60 | 1 | AF324209_1 proglucagon |
| 28 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 41.20 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
| 29 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 41.20 | 1 | glucagon-like peptide, GLP |
| 30 | Macaca mulatta | 40.80 | 3 | PREDICTED: gastric inhibitory polypeptide |
| 31 | Bos taurus | 40.40 | 5 | PREDICTED: similar to Gastric inhibitory polypepti |
| 32 | Ictalurus punctatus | 40.40 | 3 | proglucagon I |
| 33 | Sebastes caurinus | 40.00 | 4 | proglucagon II |
| 34 | Tetraodon nigroviridis | 40.00 | 2 | unnamed protein product |
| 35 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 40.00 | 2 | GLUC_CARAU Glucagon precursor |
| 36 | Heloderma horridum | 40.00 | 1 | EXE3_HELHO Exendin-3 precursor emb |
| 37 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
| 38 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
| 39 | Mus musculus | 39.70 | 6 | Gastric inhibitory polypeptide |
| 40 | Protopterus dolloi | 38.90 | 1 | proglucagon |
| 41 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 38.90 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
| 42 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 38.10 | 1 | GLUC2_PETMA Glucagon-2 precursor |
| 43 | Neoceratodus forsteri | 38.10 | 1 | proglucagon |
| 44 | synthetic construct | 37.00 | 1 | Homo sapiens glucagon |
| 45 | Phodopus sungorus | 36.60 | 1 | glucagon precursor |
| 46 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 36.60 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
| 47 | Sus scrofa | 36.20 | 1 | glucagon |
| 48 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 35.80 | 1 | GLUC_LEPSP Glucagon precursor |
| 49 | Canis lupus familiaris | 35.80 | 1 | glucagon |
| 50 | Heloderma suspectum, venom, Peptide, 39 aa | 35.40 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30-V |
| 51 | Bufo marinus | 35.40 | 1 | proglucagon |
| 52 | Hydrolagus colliei | 35.40 | 1 | proglucagon |
| 53 | Squalus acanthias | 35.40 | 1 | proglucagon |
| 54 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 34.70 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
| 55 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 34.70 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gb |
| 56 | Capra hircus | 34.30 | 1 | glucagon |
| 57 | Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | 33.50 | 1 | VIP_MOUSE VIP peptides precursor |
| 58 | Arvicanthis ansorgei | 32.70 | 1 | vasoactive intestinal polypeptide |
| 59 | swine, intestines, Peptide Partial, 56 aa | 32.30 | 1 | secretin precursor, N-prosecretin, secretin-(-9 to |
| 60 | Ambloplites rupestris | 32.30 | 1 | proglucagon |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 || |||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 123 PLSDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 |
| Pan troglodytes | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 177 || |||||||||||||||||||||||||||#||||||||||||||| +++| || | Sbjct 962 PLSDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN-SSVAYRHAE 1015 |
| N/A | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIA 172 |||||||||||||||||#|||||||||||||||+|||| Sbjct 1 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNKNNIA 37 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN 167 ||+||||||||||+|+|#||+|||||||+|||| Sbjct 1 HSEGTFTSDYSKYMDNR#RAKDFVQWLMSTKRN 32 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 164 |||||||||||||||+|#|||||+||||+| Sbjct 1 HSQGTFTSDYSKYLDNR#RAQDFIQWLMST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN 167 ||+|||++||||||++|#||||||||| |+||| Sbjct 1 HSEGTFSNDYSKYLETR#RAQDFVQWLKNSKRN 32 |
| Contains: Glucagon; Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 164 |||||||+|||||+|+|#||||||||||+| Sbjct 1 HSQGTFTNDYSKYMDTR#RAQDFVQWLMST 29 |
| Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 164 |||||||+|||||+|+|#||||||||||+| Sbjct 1 HSQGTFTNDYSKYMDTR#RAQDFVQWLMST 29 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 164 ||+||||||||||+|+|#||+|||||||+| Sbjct 1 HSEGTFTSDYSKYMDNR#RAKDFVQWLMST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN 167 ||+|||++||||||+ |#+|||||+|||| ||+ Sbjct 1 HSEGTFSNDYSKYLEDR#KAQDFVRWLMNNKRS 32 |
| Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 164 ||||+|||||||||||+#+|+||| ||||| Sbjct 1 HSQGSFTSDYSKYLDSK#QAKDFVIWLMNT 29 |
| deshis1, Desphe6, Glu9 | Query 137 SQGTFTSDYSKYLDSR#RAQDFVQWLMNT 164 |||| ||+||||||||#|||||||||||| Sbjct 1 SQGT-TSEYSKYLDSR#RAQDFVQWLMNT 27 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMN 163 ||+|||||||||||+++#+|+|||+|||| Sbjct 1 HSEGTFTSDYSKYLENK#QAKDFVRWLMN 28 |
| Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 ||||+|||||||||||+++#+|+|||+|||| || + + +|| Sbjct 41 KRHSEGTFTSDYSKYLENK#QAKDFVRWLMNAKRGGSELQRRH 82 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR---------NNIAKRHDE 177 +||+ ||||+| + |||++# |+||| || + ++| |+ ||| | Sbjct 80 RRHADGTFTNDMTSYLDAK#AARDFVSWLARSDKSRRDGGDHLAENSEDKRHAE 132 |
| Agkistrodon piscivorus | Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNI 171 +||+ |||||||+| || # |+|++||+| | + ++ Sbjct 82 RRHADGTFTSDYNKLLDDI#ATQEFLKWLINQKVTQRDL 119 Query 132 EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH---DEFERHA 182 | +||+ ||+||| | ||+ +# |++|+ ||+| + |+ | | ||| Sbjct 32 EYERHADGTYTSDISSYLEGQ#AAKEFIAWLVNGRGRRDFSEGAHTGEDLGRRHA 85 |
| Gallus gallus | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN--------------- 167 || + |+|| |||||||||||||||||||#||||||||||+|||| Sbjct 42 PLDESRQLNEVKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMSTKRNGQQGQEDKENDKFPD 101 Query 168 ---RNNIAKRHDEFERHA 182 | |+||| |||||| Sbjct 102 QLSSNAISKRHSEFERHA 119 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNI 171 +||+ |||||| +| || # |++|++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDM#AAKEFLKWLINTKVTQRDL 201 Query 131 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 169 +| +||++||+||| + ||+ +# |++|+ ||+| + |+ Sbjct 113 SEFERHAEGTYTSDITSYLEGQ#AAKEFIAWLVNGRGRRD 151 |
| Meleagris gallopavo | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN--------------- 167 || + |+|| |||||||||||||||||||#||||||||||+|||| Sbjct 42 PLDESRQLNEVKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMSTKRNGQQGQEDKENDEFPD 101 Query 168 ---RNNIAKRHDEFERHA 182 | |+||| |||||| Sbjct 102 QLSSNAISKRHSEFERHA 119 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNI 171 +||+ |||||| +| || # |++|++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDM#AAKEFLKWLINTKVTQRDL 201 Query 131 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 169 +| +||++||+||| + ||+ +# |++|+ ||+| + |+ Sbjct 113 SEFERHAEGTYTSDITSYLEGQ#AAKEFIAWLVNGRGRRD 151 |
| Monodelphis domestica | Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 +|+++||| |||| +| # |||| ||++ | +| + ||+ || | Sbjct 51 QRYAEGTFISDYSITMDKI#MQQDFVNWLLSQKGKKN--SWRHNITERKA 97 |
| Oncorhynchus tshawytscha | Query 137 SQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 | |||++||||| + |# ||||||||||+||+ +||| Sbjct 2 SXGTFSNDYSKYQEER#MAQDFVQWLMNSKRS-GAPSKRH 39 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 168 |||+ ||+||| | || +# |+||| || + + | Sbjct 37 KRHADGTYTSDVSTYLQDQ#AAKDFVSWLKSGRARR 71 |
| Rattus norvegicus | Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| #| |||| ||+ | +|+ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKI#RQQDFVNWLLAQKGKKND--WKHNLTQREA 88 |
| Canis familiaris | Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| #| |||| ||+ | +|+ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKI#RQQDFVNWLLAQKGKKND--WKHNITQREA 88 |
| Xenopus laevis | Query 126 DPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 | +|+ | |||||||||||||||||||#||||||||||||||+ +++|+ ++|||| Sbjct 43 DSEQLKEVKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRS-GELSRRNADYERHA 98 Query 125 GDPDQMNED-KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 |+ + | | +||++|||||| ++ || +# |++|+ ||+| ++ |++|+ |||||| Sbjct 85 GELSRRNADYERHAEGTFTSDVTQQLDEK#AAKEFIDWLINGGPSKEIISRRNAEFERHA 143 Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLM--NTKRNRNNIAKRHDEFERHA 182 ||++||||+| + ||+ +# |++|| ||+ ||| + + + ||| Sbjct 179 RHAEGTFTNDMTNYLEEK#AAKEFVGWLIKGRPKRNFSEVHSVEEMDRRHA 228 Query 133 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNI 171 |+||+ |+||+| +| || # ||+|+ |++||+ ++ Sbjct 224 DRRHADGSFTNDINKVLDII#AAQEFLDWVINTQETERDL 262 Query 132 EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 177 | +||++||+|+| ++||+ +# |++|++||+ | + + || | Sbjct 138 EFERHAEGTYTNDVTEYLEEK#AAKEFIEWLIKGKPKKIRYS-RHAE 182 |
| Xenopus tropicalis | Query 126 DPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 | |+ | |||||||||||||||||||#|||||+||||||||+ +++|+ ++|||| Sbjct 43 DSQQLKEVKRHSQGTFTSDYSKYLDSR#RAQDFIQWLMNTKRS-GGLSRRNADYERHA 98 Query 125 GDPDQMNED-KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 | + | | +||++|||||| +++|| +# |++|+ ||+| ++ |++|+ + |||| Sbjct 85 GGLSRRNADYERHAEGTFTSDVTQHLDEK#AAKEFIDWLINGGPSKEIISRRNADVERHA 143 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 177 +||++||+|+| ++||+ +# |++|++||+| | + + || | Sbjct 140 ERHAEGTYTNDVTEYLEEK#AAKEFIEWLINGKPKKIRYS-RHAE 182 Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 169 ||++||||+| + ||+ +# |++|| ||+ + || Sbjct 179 RHAEGTFTNDMTNYLEEK#AAKEFVGWLIKGRPKRN 213 Query 133 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 165 |+||+ |+||+| +| || # ||+|+ |++||+ Sbjct 224 DRRHADGSFTNDINKVLDII#AAQEFLDWVINTQ 256 |
| Danio rerio | Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 177 ||||+|||++||||||++|#||||||||||| ||| ++ ||| | Sbjct 48 KRHSEGTFSNDYSKYLETR#RAQDFVQWLMNAKRNGGSV-KRHAE 90 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWL 161 |||++||+||| | || +# || || || Sbjct 86 KRHAEGTYTSDVSSYLQDQ#AAQSFVAWL 113 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKR---------------- 166 || | |+|| |||||||||||||||||+|#|||||||||||||| Sbjct 40 PLDDSRQLNEVKRHSQGTFTSDYSKYLDTR#RAQDFVQWLMNTKRSGQQGVEEREKENLLD 99 Query 167 --NRNNIAKRHDEFERHA 182 + | +|+ | |+|||| Sbjct 100 QLSSNGLARHHAEYERHA 117 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNI 171 +||+ |||||||++ || # |+|++||+| | + ++ Sbjct 162 RRHADGTFTSDYNQLLDDI#ATQEFLKWLINQKVTQRDL 199 Query 132 EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 169 | +||+ | +||| | ||+ +# |++|+ ||+| + |+ Sbjct 112 EYERHADGRYTSDISSYLEGQ#AAKEFIAWLVNGRGRRD 149 |
| Heloderma suspectum | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKR---------------- 166 || | |+|| |||||||||||||||||+|#|||||||||||||| Sbjct 40 PLDDSRQLNEVKRHSQGTFTSDYSKYLDTR#RAQDFVQWLMNTKRSGQQGVEEREKENLLD 99 Query 167 --NRNNIAKRHDEFERHA 182 + | +|+ | |+|||| Sbjct 100 QLSSNGLARHHAEYERHA 117 Query 132 EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 168 | +||+ | +||| | ||+ +# |++|+ ||+| + | Sbjct 112 EYERHADGRYTSDISSYLEGQ#AAKEFIAWLVNGRGRR 148 |
| Hoplobatrachus rugulosus | Query 124 LGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 | | | || |||||||||||||||||||#|||||||||||+||+ |+||+ +||||| Sbjct 41 LDDSDHHNEVKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNSKRS-GGISKRNVQFERHA 98 Query 133 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 164 |+||+ |+||||++| || +# ||+|+ |++|| Sbjct 178 DRRHADGSFTSDFNKALDIK#AAQEFLDWIINT 209 Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 169 ||++|||||| + ||+ +# |++|| ||+ + || Sbjct 134 RHAEGTFTSDMTSYLEEK#AAKEFVDWLIKGRPKRN 168 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 177 +||++||+|+| +++|+ +# |++|+ ||+ | + ++ || | Sbjct 95 ERHAEGTYTNDVTQFLEEK#AAKEFIDWLIKGKPKKQRLS-RHAE 137 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 124 LGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 | +| + ||||+|||++||||||++|#||||||||| |+| || + +|| Sbjct 40 LTEPIEPLNMKRHSEGTFSNDYSKYLETR#RAQDFVQWLKNSK--RNGLFRRH 89 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWL 161 +||+ ||+||| | || +# |+||| || Sbjct 87 RRHADGTYTSDVSSYLQDQ#AAKDFVSWL 114 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN 167 |+ ||||+| + |||++# |+||| || + ++ Sbjct 1 HADGTFTNDMTSYLDAK#AARDFVSWLARSDKS 32 |
| Macaca mulatta | Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| # |||| ||+ | +|+ +|+ +| | Sbjct 51 RYAEGTFISDYSIAMDKI#HQQDFVNWLLAQKGKKND--WKHNITQREA 96 |
| Bos taurus | Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNN 170 |+++||| |||| +| #| |||| ||+ | +++ Sbjct 81 RYAEGTFISDYSIAMDKI#RQQDFVNWLLAQKGKKSD 116 |
| Ictalurus punctatus | Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 +|||+|||++||||||++|#|||||||||||+||+ ++ |+|| Sbjct 49 RRHSEGTFSNDYSKYLETR#RAQDFVQWLMNSKRS-DSPARRH 89 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 +|| |+|||| +| ||| # |++++||+||+ + + ||| Sbjct 134 RRHVDGSFTSDVNKVLDSL#AAKEYLQWVMNSPSSAS--GKRH 173 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWL 161 +||+ ||+||| | || +# |+||+ || Sbjct 87 RRHADGTYTSDVSSYLQDQ#AAKDFITWL 114 |
| Sebastes caurinus | Query 124 LGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 | +| ++ ||||+|||++||||||++|#||||||||| |+||| ++ +|| Sbjct 40 LAEPIELPNMKRHSEGTFSNDYSKYLETR#RAQDFVQWLKNSKRN-GSLFRRH 90 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 168 +||+ ||+||| | || +# |++|| || + | Sbjct 88 RRHADGTYTSDVSSYLQDQ#AAKEFVYWLKTGRGRR 122 |
| Tetraodon nigroviridis | Query 124 LGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 | +| ++ ||||+|||++||||||++|#||||||||| |+||| ++ +|| Sbjct 777 LTEPSDLSNMKRHSEGTFSNDYSKYLETR#RAQDFVQWLKNSKRN-GSLFRRH 827 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 168 +||+ ||+||| | || +# |++|| || + | Sbjct 825 RRHADGTYTSDVSAYLQDQ#AAKEFVSWLKTGRGRR 859 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 177 ||||+|||++||||||++|#||||||+||||+| | + |||| | Sbjct 48 KRHSEGTFSNDYSKYLETR#RAQDFVEWLMNSKSNGGS-AKRHAE 90 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWL 161 |||++||+||| | +| +# ||+|| || Sbjct 86 KRHAEGTYTSDISSFLRDQ#AAQNFVAWL 113 |
| Heloderma horridum | Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMN 163 |||| |||||| || ++ # + |++|| | Sbjct 46 KRHSDGTFTSDLSKQMEEE#AVRLFIEWLKN 75 |
| Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 ||||+|||++||||| + |# ||||||||||+||+ +||| Sbjct 50 KRHSEGTFSNDYSKYQEER#MAQDFVQWLMNSKRS-GAPSKRH 90 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNN 170 |||+ ||+||| | || +# |+||| || + + | + Sbjct 88 KRHADGTYTSDVSTYLQDQ#AAKDFVSWLKSGRARRES 124 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHD 176 +|| |+|||| +| ||| # |++++ |+| +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLDSL#AAKEYLLWVMTSKTSGKSNKRQED 177 |
| Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 || |+|||++ |||| + |# |+||+ ||||+||+ +||| Sbjct 50 KRQSEGTFSNYYSKYQEER#MARDFLHWLMNSKRS-GAPSKRH 90 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNN 170 |||+ ||+||| | || +# |+||| || + | + Sbjct 88 KRHADGTYTSDVSTYLQDQ#AAKDFVSWLKSGPARRES 124 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHD 176 +|| |+|||| +| ||| # |++++ |+| +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLDSL#AAKEYLLWVMTSKTSGKSNKRQED 177 |
| Mus musculus | Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| #| |||| ||+ + +++ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKI#RQQDFVNWLLAQRGKKSD--WKHNITQREA 88 |
| Protopterus dolloi | Query 132 EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 | |||||||| |||+| |+++# | | || ||+||| ++|||+| |||| Sbjct 28 EAKRHSQGTFMSDYAKLLEAK#HALDLVQRLMSTKRT-GAVSKRHNEIERHA 77 Query 131 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFER 180 || +||++||+||| | ||+ +# +|++||| + |+ +| +| Sbjct 71 NEIERHAEGTYTSDISSYLEGQ#AVNEFIRWLMKGRGRRDFSETDIEEMDR 120 Query 133 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 165 |+||+ || ||| + |+| # ++|+ ||+| | Sbjct 119 DRRHADGTVTSDINSVLESI#ATREFLNWLINAK 151 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 165 |+ |+|||| +| ||+ # |++|+ ||++|| Sbjct 1 HADGSFTSDINKVLDTI#AAKEFLNWLISTK 30 |
| Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN------RNNIAKRHDE 177 |||||+|||||||+|| +#+|+||| ||+|||| |+ ||| + Sbjct 43 RHSQGSFTSDYSKHLDVK#QAKDFVTWLLNTKRRGVDAQAGANLEKRHSD 91 Query 131 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKR 166 | +|||| |+||+| + || # |++|++|| | Sbjct 84 NLEKRHSDGSFTNDMNVMLDRM#SAKNFLEWLKQQGR 119 |
| Neoceratodus forsteri | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 |+ + | |||||||| |||+| |++|# | |||| ||||||| ++||| | |||| Sbjct 11 PVDASREHTEAKRHSQGTFMSDYAKLLEAR#HALDFVQRLMNTKRN-GGVSKRHSEIERHA 69 Query 131 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 169 +| +||++||+||| | ||+ +# | +||+||+ + |+ Sbjct 63 SEIERHAEGTYTSDISSYLEGQ#AANEFVRWLLKGRGRRD 101 Query 126 DPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 165 | | +||+ || |+| + |+| # ++|+ ||+|+| Sbjct 104 DTDAEEMGRRHADGTITNDMNNVLESI#ATREFLNWLINSK 143 |
| synthetic construct | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 || |||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 40 PLSDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 99 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 165 +||+ |+|+ + + ||+ # |+||+ ||+ || Sbjct 144 RRHADGSFSDEMNTILDNL#AARDFINWLIQTK 175 |
| Phodopus sungorus | Query 139 GTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 169 |||||| | ||+ +# |++|+ ||+ + |+ Sbjct 1 GTFTSDVSSYLEGQ#AAKEFIAWLVKGRGRRD 31 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 165 +||+ |+|+ + + ||| # +||+ ||+ || Sbjct 44 RRHADGSFSDEMNTILDSL#ATRDFINWLIQTK 75 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 126 DPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 +| +++ ||||+|||++||||||+ |#+||+||+|||| ||+ ||| Sbjct 43 EPRELSNMKRHSEGTFSNDYSKYLEDR#KAQEFVRWLMNNKRS-GVAEKRH 91 Query 133 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWL 161 +|||+ |||||| | || +# +||| | Sbjct 88 EKRHADGTFTSDVSSYLKDQ#AIKDFVDRL 116 |
| Sus scrofa | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 || ||||| |||||||||||||||||||||#|||||||||||||||+|||||||||||||| Sbjct 40 PLDDPDQMTEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNKNNIAKRHDEFERHA 99 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 165 +||+ |+|+ + + ||+ # +||+ ||++|| Sbjct 144 RRHADGSFSDEMNTVLDNL#ATRDFINWLLHTK 175 |
| Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRN 167 |||||||+|||||||+|#||||||||||+|||+ Sbjct 1 HSQGTFTNDYSKYLDTR#RAQDFVQWLMSTKRS 32 Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 168 |+ ||+||| | || +# |+ || || + | Sbjct 45 HADGTYTSDVSSYLQDQ#AAKKFVTWLKQGQDRR 77 |
| Canis lupus familiaris | Query 123 PLGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 || | |||||||||||||||||||||||||#|||||||||||||||+|||||||||||||| Sbjct 40 PLNDLDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNKNNIAKRHDEFERHA 99 Query 131 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 169 +| +||++|||||| | ||+ +# |++|+ ||+ + |+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQ#AAKEFIAWLVKGRGRRD 131 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTK 165 +||+ |+|+ + + ||+ # +||+ ||+ || Sbjct 144 RRHADGSFSDEMNTVLDTL#ATRDFINWLLQTK 175 |
| Heloderma suspectum, venom, Peptide, 39 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMN 163 | +|||||| || ++ # + |++|| | Sbjct 1 HGEGTFTSDLSKQMEEE#AVRLFIEWLKN 28 |
| Bufo marinus | Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLM--NTKRNRNNIAKRHDEFERHA 182 ||++|||||| + +|+ +# |++|| ||+ ||| ++++ | ||| Sbjct 62 RHAEGTFTSDMTSFLEEK#AAKEFVDWLIKGRPKRNFSDVSAADDMDRRHA 111 Query 133 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNT 164 |+||+ |+||||++| || +# ||+|+ |++|| Sbjct 107 DRRHADGSFTSDFNKALDIK#AAQEFLDWIINT 138 Query 134 KRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDE 177 +||++||+|+| +++|+ +# |++|+ ||+ + ++ || | Sbjct 23 ERHAEGTYTNDVTQFLEEK#AAKEFIDWLLKGIPKKQRLS-RHAE 65 Query 156 DFVQWLMNTKRNRNNIAKRHDEFERHA 182 || |||||+||+ +++|+ +||||| Sbjct 1 DFAQWLMNSKRS-GGMSRRNVQFERHA 26 |
| Hydrolagus colliei | Query 124 LGDPDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 + +| + + |||+ | |+||||||||+|#| +||||||++|||| | |+ +||| Sbjct 20 VSNPSTVTDVKRHTDGIFSSDYSKYLDNR#RTKDFVQWLLSTKRNGANT----DKTKRHA 74 Query 131 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNN--IAKRHDEFER 180 ++ |||+ | +||| + | #+++ ||+ | | + +|+ ++||| | | Sbjct 68 DKTKRHADGIYTSDVASLTDYL#KSKRFVESLSNYNKRQNDRRMSKRHVEGAR 119 Query 132 EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFE 179 | | ++ + +|+| ||+++# |+||+ ||+ + | + |+ | | Sbjct 116 EGARRTEEDYPNDFSSYLEAK#AAKDFIDWLIK-GQGRRDFAEESREIE 162 |
| Squalus acanthias | Query 127 PDQMNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFE 179 |++| |+||+ |||||+ + ||+ # |++|+ |++|+| | | | | Sbjct 118 PEEM--DRRHADGTFTSEINIVLDTI#AAKEFLNWILNSK----TIQSRDSEIE 164 Query 131 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWL--MNTKRNRNNIAKRHDEFERH 181 ++ |||++||+||| | #+|+ || | | ++| +|+||| | || Sbjct 20 DKTKRHAEGTYTSDVDSLSDYF#KAKRFVDSLTSYNKRQNGRSISKRHVESTRH 72 Query 150 DSR#RAQDFVQWLMNTKRNRNNIAKRHDE 177 |+|#||+|||||||+|||| + ||| | Sbjct 1 DNR#RAKDFVQWLMSTKRNGDK-TKRHAE 27 Query 132 EDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 168 | ||++|++ | | ||+++# |+||+ ||+ + | Sbjct 68 ESTRHTEGSYR-DISSYLEAK#AAKDFINWLIKGRGRR 103 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 168 |+ || ||| | +|+ +# ++|+ ||++ + | Sbjct 1 HADGTLTSDISSFLEKQ#ATKEFIAWLVSGRGRR 33 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 139 GTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRN 169 ||+||| | || +# |++|| || + |+ Sbjct 3 GTYTSDVSSYLQDQ#AAKEFVSWLKTGRGRRD 33 |
| Capra hircus | Query 131 NEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNR 168 +| +||++|||||| | ||+ +# |++|+ ||+ + | Sbjct 8 DEFERHAEGTFTSDVSSYLEGQ#AAKEFIAWLVKGRGRR 45 Query 169 NNIAKRHDEFERHA 182 |||||||||||||| Query 169 NNIAKRHDEFERHA 182 |
| Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | Query 130 MNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 ++ + ||+ | ||||||+ | # |+ +++ |+ || ++|++ +||+ Sbjct 75 VSRNARHADGVFTSDYSRLLGQI#SAKKYLESLIG-KRISSSISEDPVPIKRHS 126 |
| Arvicanthis ansorgei | Query 130 MNEDKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRHDEFERHA 182 ++ + ||+ | ||||||+ | # |+ +++ |+ || ++| + +||+ Sbjct 58 VSRNARHADGVFTSDYSRLLGQI#SAKKYLESLIG-KRISSSILEDPVPIKRHS 109 |
| swine, intestines, Peptide Partial, 56 aa | Query 135 RHSQGTFTSDYSKYLDSR#RAQDFVQWLM 162 ||| |||||+ |+ || #| | +| |+ Sbjct 29 RHSDGTFTSELSRLRDSA#RLQRLLQGLV 56 |
| Ambloplites rupestris | Query 136 HSQGTFTSDYSKYLDSR#RAQDFVQWLMNTKRNRNNIAKRH 175 |||||||+||+ ||+ |#+||||++|||| ||+ ||| Sbjct 1 HSQGTFTNDYTNYLEDR#QAQDFIRWLMNNKRS-GAAEKRH 39 Query 133 DKRHSQGTFTSDYSKYLDSR#RAQDFVQWLMN--------TKRNRNNIAKRHDE 177 +|||+ |||| | | +# +||| | + | | | ++|| | Sbjct 36 EKRHADGTFTDDASSDFYDQ#AIKDFVAKLKSGQDRREPETDRRREAFSRRHVE 88 |
[Site 3] SRRAQDFVQW160-LMNTKRNRNN
Trp160 Leu
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ser151 | Arg152 | Arg153 | Ala154 | Gln155 | Asp156 | Phe157 | Val158 | Gln159 | Trp160 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Leu161 | Met162 | Asn163 | Thr164 | Lys165 | Arg166 | Asn167 | Arg168 | Asn169 | Asn170 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| NEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDV |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 127.00 | 10 | glucagon, isoform CRA_b |
| 2 | N/A | 79.70 | 45 | 0 |
| 3 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 64.70 | 1 | AAB31092.1 |
| 4 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 61.60 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
| 5 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 60.80 | 1 | glucagon II |
| 6 | Contains: Glucagon; Glucagon-like peptide | 60.10 | 4 | GLUC_AMICA Glucagon precursor |
| 7 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 60.10 | 1 | glucagon |
| 8 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 58.50 | 1 | glucagon G-29 |
| 9 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 57.80 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gb |
| 10 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.20 | 1 | GLUC_LAMFL Glucagon gb |
| 11 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 53.50 | 1 | glucagon |
| 12 | deshis1, Desphe6, Glu9 | 53.50 | 1 | A Chain A, Nmr Solution Structure Of The Glucagon |
| 13 | Monodelphis domestica | 48.90 | 3 | PREDICTED: similar to Gastric inhibitory polypepti |
| 14 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 48.90 | 1 | GLUC1_PETMA Glucagon-1 precursor |
| 15 | Xenopus laevis | 47.00 | 5 | proglucagon II |
| 16 | Hoplobatrachus rugulosus | 46.60 | 1 | AF324209_1 proglucagon |
| 17 | Bufo marinus | 46.60 | 1 | proglucagon |
| 18 | Gallus gallus | 46.20 | 4 | glucagon isoform 1 |
| 19 | Meleagris gallopavo | 46.20 | 2 | preproglucagon B |
| 20 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | 44.70 | 1 | GLUC_HELSU Glucagon precursor |
| 21 | Capra hircus | 43.90 | 1 | glucagon |
| 22 | Oncorhynchus tshawytscha | 43.50 | 1 | S78474_1 proglucagon |
| 23 | Ictalurus punctatus | 43.10 | 3 | proglucagon I |
| 24 | Rattus norvegicus | 42.70 | 6 | Glucose-dependent insulinotropic peptide |
| 25 | Canis familiaris | 42.70 | 2 | PREDICTED: similar to Gastric inhibitory polypepti |
| 26 | Ambloplites rupestris | 42.70 | 1 | proglucagon |
| 27 | Pan troglodytes | 42.40 | 2 | PREDICTED: fibroblast activation protein, alpha su |
| 28 | Xenopus tropicalis | 42.40 | 2 | glucagon |
| 29 | Danio rerio | 42.00 | 6 | hypothetical protein LOC494052 |
| 30 | Bos taurus | 42.00 | 5 | vasoactive intestinal peptide |
| 31 | Macaca mulatta | 41.60 | 3 | PREDICTED: vasoactive intestinal peptide |
| 32 | Heloderma suspectum | 41.60 | 2 | proglucagon |
| 33 | Squalus acanthias | 41.60 | 1 | proglucagon |
| 34 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 41.20 | 1 | glucagon-like peptide, GLP |
| 35 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 41.20 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
| 36 | Sebastes caurinus | 40.80 | 4 | proglucagon I |
| 37 | Tetraodon nigroviridis | 40.00 | 3 | unnamed protein product |
| 38 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 40.00 | 2 | GLUC_CARAU Glucagon precursor |
| 39 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
| 40 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
| 41 | Heloderma horridum | 40.00 | 1 | EXE3_HELHO Exendin-3 precursor emb |
| 42 | Mus musculus | 39.70 | 6 | Gastric inhibitory polypeptide |
| 43 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 38.90 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
| 44 | Protopterus dolloi | 38.90 | 1 | proglucagon |
| 45 | Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | 38.50 | 1 | VIP_MOUSE VIP peptides precursor |
| 46 | Agkistrodon piscivorus | 38.50 | 1 | proglucagon |
| 47 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 38.10 | 1 | GLUC2_PETMA Glucagon-2 precursor |
| 48 | Arvicanthis ansorgei | 37.70 | 1 | vasoactive intestinal polypeptide |
| 49 | synthetic construct | 37.00 | 1 | Homo sapiens glucagon |
| 50 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 36.60 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
| 51 | Phodopus sungorus | 36.60 | 1 | glucagon precursor |
| 52 | Neoceratodus forsteri | 36.20 | 1 | proglucagon |
| 53 | Sus scrofa | 36.20 | 1 | glucagon |
| 54 | Canis lupus familiaris | 35.80 | 1 | glucagon |
| 55 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 35.80 | 1 | GLUC_LEPSP Glucagon precursor |
| 56 | Hydrolagus colliei | 35.40 | 1 | proglucagon |
| 57 | Heloderma suspectum, venom, Peptide, 39 aa | 35.40 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30-V |
| 58 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 34.70 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gb |
| 59 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 34.70 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSD 189 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||| Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSD 189 |
| N/A | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIA 172 |||||||||||||||||||||||||#|||||||+|||| Sbjct 1 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNKNNIA 37 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN 167 ||+||||||||||+|+|||+|||||#||+|||| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDFVQW#LMSTKRN 32 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 164 |||||||||||||||+||||||+||#||+| Sbjct 1 HSQGTFTSDYSKYLDNRRAQDFIQW#LMST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN 167 ||+|||++||||||++|||||||||#| |+||| Sbjct 1 HSEGTFSNDYSKYLETRRAQDFVQW#LKNSKRN 32 |
| Contains: Glucagon; Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 164 |||||||+|||||+|+|||||||||#||+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDFVQW#LMST 29 |
| Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 164 |||||||+|||||+|+|||||||||#||+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDFVQW#LMST 29 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 164 ||+||||||||||+|+|||+|||||#||+| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDFVQW#LMST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN 167 ||+|||++||||||+ |+|||||+|#||| ||+ Sbjct 1 HSEGTFSNDYSKYLEDRKAQDFVRW#LMNNKRS 32 |
| Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 164 ||||+|||||||||||++|+||| |#|||| Sbjct 1 HSQGSFTSDYSKYLDSKQAKDFVIW#LMNT 29 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMN 163 ||+|||||||||||++++|+|||+|#||| Sbjct 1 HSEGTFTSDYSKYLENKQAKDFVRW#LMN 28 |
| deshis1, Desphe6, Glu9 | Query 137 SQGTFTSDYSKYLDSRRAQDFVQW#LMNT 164 |||| ||+||||||||||||||||#|||| Sbjct 1 SQGT-TSEYSKYLDSRRAQDFVQW#LMNT 27 |
| Monodelphis domestica | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGT 185 +|+++||| |||| +| |||| |#|++ | +| + ||+ || |+|| Sbjct 51 QRYAEGTFISDYSITMDKIMQQDFVNW#LLSQKGKKN--SWRHNITERKADGT 100 |
| Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||+|||||||||||++++|+|||+|#||| || + + + |||+||||+|+ Sbjct 41 KRHSEGTFTSDYSKYLENKQAKDFVRW#LMNAKRGGSELQR------RHADGTFTNDM 91 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR---NNIAKRHDEFERHAE 183 +||+ ||||+| + |||++ |+||| |#| + ++| + + | +|||| Sbjct 80 RRHADGTFTNDMTSYLDAKAARDFVSW#LARSDKSRRDGGDHLAENSEDKRHAE 132 |
| Xenopus laevis | Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 | |||||||||||||||||||||||||||#||||||+ +++|+ ++|||||||||||| Sbjct 49 EVKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRS-GGLSRRNADYERHAEGTFTSDV 106 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 | +||++||+|+| ++||+ + + |++|#|+ | + + ||||||||+|+ Sbjct 138 EIERHAEGTYTNDVTEYLEEKATKAFIEW#LIKGK-------PKKIRYSRHAEGTFTNDM 189 Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRH 175 ||++||||+| + ||+ + |++|| |#|+| + | ++ + | Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEFVGW#LINGRPKRKDLLEEH 219 |
| Hoplobatrachus rugulosus | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 || |||||||||||||||||||||||||||#|||+||+ |+||+ +||||||||+|+|| Sbjct 48 NEVKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNSKRS-GGISKRNVQFERHAEGTYTNDV 106 Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFE-RHAEGTFTSD 189 ||++|||||| + ||+ + |++|| |#|+ + || +| + |||+|+|||| Sbjct 134 RHAEGTFTSDMTSYLEEKAAKEFVDW#LIKGRPKRNFPDISAEEMDRRHADGSFTSD 189 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 +||++||+|+| +++|+ + |++|+ |#|+ | + ++ ||||||||||+ Sbjct 95 ERHAEGTYTNDVTQFLEEKAAKEFIDW#LIKGKPKKQRLS-------RHAEGTFTSDM 144 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 164 |+||+ |+||||++| || + ||+|+ |#++|| Sbjct 178 DRRHADGSFTSDFNKALDIKAAQEFLDW#IINT 209 |
| Bufo marinus | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LM--NTKRNRNNIAKRHDEFERHAEGTFTSD 189 ||++|||||| + +|+ + |++|| |#|+ ||| ++++ | |||+|+|||| Sbjct 62 RHAEGTFTSDMTSFLEEKAAKEFVDW#LIKGRPKRNFSDVSAADDMDRRHADGSFTSD 118 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 +||++||+|+| +++|+ + |++|+ |#|+ | |+ ||||||||||+ Sbjct 23 ERHAEGTYTNDVTQFLEEKAAKEFIDW#LL------KGIPKK-QRLSRHAEGTFTSDM 72 Query 156 DFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 || ||#|||+||+ +++|+ +||||||||+|+|| Sbjct 1 DFAQW#LMNSKRS-GGMSRRNVQFERHAEGTYTNDV 34 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNT 164 |+||+ |+||||++| || + ||+|+ |#++|| Sbjct 107 DRRHADGSFTSDFNKALDIKAAQEFLDW#IINT 138 |
| Gallus gallus | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN------------------RNNIA 172 || |||||||||||||||||||||||||||#||+|||| | |+ Sbjct 50 NEVKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMSTKRNGQQGQEDKENDKFPDQLSSNAIS 109 Query 173 KRHDEFERHAEGTFTSDV 190 ||| |||||||||+|||+ Sbjct 110 KRHSEFERHAEGTYTSDI 127 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAK---RHDEFERHAEGTFT 187 +| +||++||+||| + ||+ + |++|+ |#|+| + |+ | + |||+|||| Sbjct 113 SEFERHAEGTYTSDITSYLEGQAAKEFIAW#LVNGRGRRDFPEKALMAEEMGRRHADGTFT 172 Query 188 SDV 190 ||+ Sbjct 173 SDI 175 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNI 171 +||+ |||||| +| || |++|++|#|+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEFLKW#LINTKVTQRDL 201 |
| Meleagris gallopavo | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN------------------RNNIA 172 || |||||||||||||||||||||||||||#||+|||| | |+ Sbjct 50 NEVKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMSTKRNGQQGQEDKENDEFPDQLSSNAIS 109 Query 173 KRHDEFERHAEGTFTSDV 190 ||| |||||||||+|||+ Sbjct 110 KRHSEFERHAEGTYTSDI 127 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAK---RHDEFERHAEGTFT 187 +| +||++||+||| + ||+ + |++|+ |#|+| + |+ | + |||+|||| Sbjct 113 SEFERHAEGTYTSDITSYLEGQAAKEFIAW#LVNGRGRRDFPEKALMAEEMGRRHADGTFT 172 Query 188 SDV 190 ||+ Sbjct 173 SDI 175 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNI 171 +||+ |||||| +| || |++|++|#|+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEFLKW#LINTKVTQRDL 201 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKR------------------NRNNIA 172 || |||||||||||||||||+|||||||||#|||||| + | +| Sbjct 48 NEVKRHSQGTFTSDYSKYLDTRRAQDFVQW#LMNTKRSGQQGVEEREKENLLDQLSSNGLA 107 Query 173 KRHDEFERHAEGTFTSDV 190 + | |+||||+| +|||+ Sbjct 108 RHHAEYERHADGRYTSDI 125 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAK---RHDEFERHAEGTFTS 188 | +||+ | +||| | ||+ + |++|+ |#|+| + |+ + + | |||+||||| Sbjct 112 EYERHADGRYTSDISSYLEGQAAKEFIAW#LVNGRGRRDFLEEAGTADDIGRRHADGTFTS 171 Query 189 D 189 | Query 189 D 189 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNI 171 +||+ |||||||++ || |+|++|#|+| | + ++ Sbjct 162 RRHADGTFTSDYNQLLDDIATQEFLKW#LINQKVTQRDL 199 |
| Capra hircus | Query 169 NNIAKRHDEFERHAEGTFTSDV 190 |||||||||||||||||||||| Query 169 NNIAKRHDEFERHAEGTFTSDV 190 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 168 +| +||++|||||| | ||+ + |++|+ |#|+ + | Sbjct 8 DEFERHAEGTFTSDVSSYLEGQAAKEFIAW#LVKGRGRR 45 |
| Oncorhynchus tshawytscha | Query 137 SQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 | |||++||||| + | |||||||#|||+||+ +|||+||+|||| Sbjct 2 SXGTFSNDYSKYQEERMAQDFVQW#LMNSKRS-------GAPSKRHADGTYTSDV 48 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 168 |||+ ||+||| | || + |+||| |#| + + | Sbjct 37 KRHADGTYTSDVSTYLQDQAAKDFVSW#LKSGRARR 71 |
| Ictalurus punctatus | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 +|||+|||++||||||++|||||||||#|||+||+ |||+||+|||| Sbjct 49 RRHSEGTFSNDYSKYLETRRAQDFVQW#LMNSKRS-------DSPARRHADGTYTSDV 98 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEF--ERHAEGTFTSDV 190 +||+ ||+||| | || + |+||+ |#| + + + + | + || +|+||||| Sbjct 87 RRHADGTYTSDVSSYLQDQAAKDFITW#LKSGQPKPDAVETRSVDTLRRRHVDGSFTSDV 145 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRH 175 +|| |+|||| +| ||| |++++||#+||+ + + ||| Sbjct 134 RRHVDGSFTSDVNKVLDSLAAKEYLQW#VMNSPSSAS--GKRH 173 |
| Rattus norvegicus | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| | |||| |#|+ | +|+ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNW#LLAQKGKKND--WKHNLTQREA 88 |
| Canis familiaris | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| | |||| |#|+ | +|+ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNW#LLAQKGKKND--WKHNITQREA 88 |
| Ambloplites rupestris | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSD 189 |||||||+||+ ||+ |+||||++|#||| | |+ |++ |||+|||| | Sbjct 1 HSQGTFTNDYTNYLEDRQAQDFIRW#LMNNK--RSGAAEK-----RHADGTFTDD 47 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDE--FERHAEGTFTSDV 190 +|||+ |||| | | + +||| #| + + | | | || ||+||||+ Sbjct 36 EKRHADGTFTDDASSDFYDQAIKDFVAK#LKSGQDRREPETDRRREAFSRRHVEGSFTSDI 95 |
| Pan troglodytes | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||||||||||||||||||||||||||||#||||||| +++| ||||||||||| Sbjct 970 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN-SSVA------YRHAEGTFTSDV 1022 Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 168 ||++|||||| | ||+ + |++|+ |#|+ + | Sbjct 1012 RHAEGTFTSDVSSYLEGQAAKEFIAW#LVKGRGRR 1045 |
| Xenopus tropicalis | Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 | ||||||||||||||||||||||||+||#||||||+ +++|+ ++|||||||||||| Sbjct 49 EVKRHSQGTFTSDYSKYLDSRRAQDFIQW#LMNTKRS-GGLSRRNADYERHAEGTFTSDV 106 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 +||++||+|+| ++||+ + |++|++|#|+| | + + ||||||||+|+ Sbjct 140 ERHAEGTYTNDVTEYLEEKAAKEFIEW#LINGK-------PKKIRYSRHAEGTFTNDM 189 Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFE---RHAEGTFTSDV 190 ||++||||+| + ||+ + |++|| |#|+ | + | ++ | | |||+|+||+|+ Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEFVGW#LIK-GRPKRNFSEAHSVEEMDRRHADGSFTNDI 236 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 165 |+||+ |+||+| +| || ||+|+ |#++||+ Sbjct 224 DRRHADGSFTNDINKVLDIIAAQEFLDW#VINTQ 256 |
| Danio rerio | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||+|||++||||||++|||||||||#||| ||| ++ +||||||+|||| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDFVQW#LMNAKRNGGSV-------KRHAEGTYTSDV 97 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#L 161 |||++||+||| | || + || || |#| Sbjct 86 KRHAEGTYTSDVSSYLQDQAAQSFVAW#L 113 |
| Bos taurus | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSD 189 ||+ | ||||||+ | |+ +++ #|+ || |+|++ +||++ || + Sbjct 80 RHADGVFTSDYSRLLGQLSAKKYLES#LIG-KRVSNSISEDQGPIKRHSDAVFTDN 133 |
| Macaca mulatta | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSD 189 + + ||+ | ||||+|| | |+ +++ #|| || +||++ +||++ || + Sbjct 76 SRNARHADGVFTSDFSKLLGQLSAKKYLES#LMG-KRVSSNISEDPVPVKRHSDAVFTDN 133 |
| Heloderma suspectum | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKR------------------NRNNIA 172 || |||||||||||||||||+|||||||||#|||||| + | +| Sbjct 48 NEVKRHSQGTFTSDYSKYLDTRRAQDFVQW#LMNTKRSGQQGVEEREKENLLDQLSSNGLA 107 Query 173 KRHDEFERHAEGTFTSDV 190 + | |+||||+| +|||+ Sbjct 108 RHHAEYERHADGRYTSDI 125 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 168 | +||+ | +||| | ||+ + |++|+ |#|+| + | Sbjct 112 EYERHADGRYTSDISSYLEGQAAKEFIAW#LVNGRGRR 148 |
| Squalus acanthias | Query 150 DSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 |+|||+|||||#||+|||| |+ +||||||+|||| Sbjct 1 DNRRAKDFVQW#LMSTKRN-------GDKTKRHAEGTYTSDV 34 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#L--MNTKRNRNNIAKRHDEFERHAEGTF 186 ++ |||++||+||| | +|+ || #| | ++| +|+||| | || ||++ Sbjct 20 DKTKRHAEGTYTSDVDSLSDYFKAKRFVDS#LTSYNKRQNGRSISKRHVESTRHTEGSY 77 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN---------NIAKRHDEFERHA 182 | ||++|++ | | ||+++ |+||+ |#|+ + | | + ||| Sbjct 68 ESTRHTEGSYR-DISSYLEAKAAKDFINW#LIKGRGRREFPEESKEIVNEVIPEEMDRRHA 126 Query 183 EGTFTSDV 190 +|||||++ Sbjct 127 DGTFTSEI 134 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFE 179 |+||+ |||||+ + ||+ |++|+ |#++|+| | | | | Sbjct 122 DRRHADGTFTSEINIVLDTIAAKEFLNW#ILNSK----TIQSRDSEIE 164 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRN 167 |+ ||||+| + |||++ |+||| |#| + ++ Sbjct 1 HADGTFTNDMTSYLDAKAARDFVSW#LARSDKS 32 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||+|||++||||||++|||||||||#| |+||| | |||+||+|||| Sbjct 50 KRHSEGTFSNDYSKYLETRRAQDFVQW#LKNSKRN--------GLFRRHADGTYTSDV 98 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#L 161 +||+ ||+||| | || + |+||| |#| Sbjct 87 RRHADGTYTSDVSSYLQDQAAKDFVSW#L 114 |
| Sebastes caurinus | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||+|||++|||+||+ |+|||||+|#||| ||+ || +|||+||||||| Sbjct 48 KRHSEGTFSNDYSRYLEERKAQDFVRW#LMNNKRS------GADE-KRHADGTFTSDV 97 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDE--FERHAEGTFTSD 189 ++|||+ |||||| | || + +||| #| + + | + + | || +|+|||| Sbjct 84 DEKRHADGTFTSDVSSYLKDQAIKDFVNR#LKSGQVRRESETEWRGEAFSRRHVDGSFTSD 143 Query 190 V 190 | Query 190 V 190 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDE 177 +|| |+|||| +| ||| |++++ |#+| +| + + ++ |+ Sbjct 133 RRHVDGSFTSDVNKVLDSMAAKEYLLW#VMTSKPSGESKKRQEDQ 176 |
| Tetraodon nigroviridis | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||+|||++||||||++|||||||||#| |+||| + | |||+||+|||| Sbjct 787 KRHSEGTFSNDYSKYLETRRAQDFVQW#LKNSKRNGS-------LFRRHADGTYTSDV 836 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 168 +||+ ||+||| | || + |++|| |#| + | Sbjct 825 RRHADGTYTSDVSAYLQDQAAKEFVSW#LKTGRGRR 859 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||+|||++||||||++|||||||+|#|||+| | + +||||||+|||+ Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDFVEW#LMNSKSNGGSA-------KRHAEGTYTSDI 97 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#L 161 |||++||+||| | +| + ||+|| |#| Sbjct 86 KRHAEGTYTSDISSFLRDQAAQNFVAW#L 113 |
| Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 || |+|||++ |||| + | |+||+ |#|||+||+ +|||+||+|||| Sbjct 50 KRQSEGTFSNYYSKYQEERMARDFLHW#LMNSKRS-------GAPSKRHADGTYTSDV 99 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHD--EFERHAEGTFTSDV 190 |||+ ||+||| | || + |+||| |#| + | + + + || +|+||||| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDFVSW#LKSGPARRESAEESMNGPMSRRHVDGSFTSDV 146 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHD 176 +|| |+|||| +| ||| |++++ |#+| +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEYLLW#VMTSKTSGKSNKRQED 177 |
| Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||+|||++||||| + | |||||||#|||+||+ +|||+||+|||| Sbjct 50 KRHSEGTFSNDYSKYQEERMAQDFVQW#LMNSKRS-------GAPSKRHADGTYTSDV 99 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNI--AKRHDEFERHAEGTFTSDV 190 |||+ ||+||| | || + |+||| |#| + + | + ++ || +|+||||| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDFVSW#LKSGRARRESAEESRNGPMSRRHVDGSFTSDV 146 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHD 176 +|| |+|||| +| ||| |++++ |#+| +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEYLLW#VMTSKTSGKSNKRQED 177 |
| Heloderma horridum | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMN 163 |||| |||||| || ++ + |++|#| | Sbjct 46 KRHSDGTFTSDLSKQMEEEAVRLFIEW#LKN 75 |
| Mus musculus | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| | |||| |#|+ + +++ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNW#LLAQRGKKSD--WKHNITQREA 88 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 165 |+ |+|||| +| ||+ |++|+ |#|++|| Sbjct 1 HADGSFTSDINKVLDTIAAKEFLNW#LISTK 30 |
| Protopterus dolloi | Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 | |||||||| |||+| |+++ | | || #||+||| ++|||+| |||||||+|||+ Sbjct 28 EAKRHSQGTFMSDYAKLLEAKHALDLVQR#LMSTKRT-GAVSKRHNEIERHAEGTYTSDI 85 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFE-RHAEGTFTSD 189 || +||++||+||| | ||+ + +|++|#|| + |+ +| + |||+|| ||| Sbjct 71 NEIERHAEGTYTSDISSYLEGQAVNEFIRW#LMKGRGRRDFSETDIEEMDRRHADGTVTSD 130 Query 190 V 190 + Sbjct 131 I 131 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 165 |+||+ || ||| + |+| ++|+ |#|+| | Sbjct 119 DRRHADGTVTSDINSVLESIATREFLNW#LINAK 151 |
| Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSD 189 + + ||+ | ||||||+ | |+ +++ #|+ || ++|++ +||++ || + Sbjct 76 SRNARHADGVFTSDYSRLLGQISAKKYLES#LIG-KRISSSISEDPVPIKRHSDAVFTDN 133 |
| Agkistrodon piscivorus | Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRH---DEFERHAEGTFTS 188 | +||+ ||+||| | ||+ + |++|+ |#|+| + |+ | | |||+||||| Sbjct 32 EYERHADGTYTSDISSYLEGQAAKEFIAW#LVNGRGRRDFSEGAHTGEDLGRRHADGTFTS 91 Query 189 D 189 | Query 189 D 189 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNI 171 +||+ |||||||+| || |+|++|#|+| | + ++ Sbjct 82 RRHADGTFTSDYNKLLDDIATQEFLKW#LINQKVTQRDL 119 Query 149 LDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 |+ | ++|+ #| + | +|+ | |+||||+||+|||+ Sbjct 9 LEDREKENFLDQ#LAS-----NGLARPHAEYERHADGTYTSDI 45 |
| Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 |||||+|||||||+|| ++|+||| |#|+|||| + + +||++|+||+|+ Sbjct 43 RHSQGSFTSDYSKHLDVKQAKDFVTW#LLNTKRRGVDAQAGANLEKRHSDGSFTNDM 98 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKR 166 | +|||| |+||+| + || |++|++|#| | Sbjct 84 NLEKRHSDGSFTNDMNVMLDRMSAKNFLEW#LKQQGR 119 |
| Arvicanthis ansorgei | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSD 189 + + ||+ | ||||||+ | |+ +++ #|+ || ++| + +||++ || + Sbjct 59 SRNARHADGVFTSDYSRLLGQISAKKYLES#LIG-KRISSSILEDPVPIKRHSDAVFTDN 116 |
| synthetic construct | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN---NIAKRHDEFERHAEGTFT 187 +| +||++|||||| | ||+ + |++|+ |#|+ + |+ +| + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEFIAW#LVKGRGRRDFPEEVAIVEELGRRHADGSFS 152 Query 188 SDV 190 ++ Sbjct 153 DEM 155 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 165 +||+ |+|+ + + ||+ |+||+ |#|+ || Sbjct 144 RRHADGSFSDEMNTILDNLAARDFINW#LIQTK 175 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||+|||++||||||+ |+||+||+|#||| | |+ +|++ |||+||||||| Sbjct 51 KRHSEGTFSNDYSKYLEDRKAQEFVRW#LMNNK--RSGVAEK-----RHADGTFTSDV 100 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQW#L 161 +|||+ |||||| | || + +||| #| Sbjct 88 EKRHADGTFTSDVSSYLKDQAIKDFVDR#L 116 |
| Phodopus sungorus | Query 139 GTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN---NIAKRHDEFERHAEGTFTSDV 190 |||||| | ||+ + |++|+ |#|+ + |+ + + |||+|+|+ ++ Sbjct 1 GTFTSDVSSYLEGQAAKEFIAW#LVKGRGRRDFPEEVTIVEELGRRHADGSFSDEM 55 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 165 +||+ |+|+ + + ||| +||+ |#|+ || Sbjct 44 RRHADGSFSDEMNTILDSLATRDFINW#LIQTK 75 |
| Neoceratodus forsteri | Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 | |||||||| |||+| |++| | |||| #||||||| ++||| | |||||||+|||+ Sbjct 20 EAKRHSQGTFMSDYAKLLEARHALDFVQR#LMNTKRN-GGVSKRHSEIERHAEGTYTSDI 77 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEF-ERHAEGTFTSD 189 +| +||++||+||| | ||+ + | +||+|#|+ + |+ +| |||+|| |+| Sbjct 63 SEIERHAEGTYTSDISSYLEGQAANEFVRW#LLKGRGRRDFSDTDAEEMGRRHADGTITND 122 Query 190 V 190 + Sbjct 123 M 123 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 165 +||+ || |+| + |+| ++|+ |#|+|+| Sbjct 112 RRHADGTITNDMNNVLESIATREFLNW#LINSK 143 |
| Sus scrofa | Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 |||||||||||||||||||||||||||||#|||||||+|||||||||||||||||||||| Sbjct 49 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNKNNIAKRHDEFERHAEGTFTSDV 107 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN---NIAKRHDEFERHAEGTFT 187 +| +||++|||||| | ||+ + |++|+ |#|+ + |+ + + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEFIAW#LVKGRGRRDFPEEVTIVEELRRRHADGSFS 152 Query 188 SDV 190 ++ Sbjct 153 DEM 155 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 165 +||+ |+|+ + + ||+ +||+ |#|++|| Sbjct 144 RRHADGSFSDEMNTVLDNLATRDFINW#LLHTK 175 |
| Canis lupus familiaris | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 ||||||||||||||||||||||||||||||#|||||||+|||||||||||||||||||||| Sbjct 48 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNKNNIAKRHDEFERHAEGTFTSDV 107 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN---NIAKRHDEFERHAEGTFT 187 +| +||++|||||| | ||+ + |++|+ |#|+ + |+ +| + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEFIAW#LVKGRGRRDFPEEVAIVEEFRRRHADGSFS 152 Query 188 SDV 190 ++ Sbjct 153 DEM 155 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTK 165 +||+ |+|+ + + ||+ +||+ |#|+ || Sbjct 144 RRHADGSFSDEMNTVLDTLATRDFINW#LLQTK 175 |
| Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 |||||||+|||||||+|||||||||#||+|||+ | ||+||+|||| Sbjct 1 HSQGTFTNDYSKYLDTRRAQDFVQW#LMSTKRS-GGITXXXXXXXXHADGTYTSDV 54 Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 168 |+ ||+||| | || + |+ || |#| + | Sbjct 45 HADGTYTSDVSSYLQDQAAKKFVTW#LKQGQDRR 77 |
| Hydrolagus colliei | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFERHAEGTFTSDV 190 |||+ | |+||||||||+|| +|||||#|++|||| | |+ +|||+| +|||| Sbjct 30 KRHTDGIFSSDYSKYLDNRRTKDFVQW#LLSTKRNGANT----DKTKRHADGIYTSDV 82 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNN--IAKRHDEFERHAEGTFTS 188 ++ |||+ | +||| + | +++ ||+ #| | + +|+ ++||| | | | + + Sbjct 68 DKTKRHADGIYTSDVASLTDYLKSKRFVES#LSNYNKRQNDRRMSKRHVEGARRTEEDYPN 127 Query 189 D 189 | Query 189 D 189 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRNNIAKRHDEFE 179 | | ++ + +|+| ||+++ |+||+ |#|+ + | + |+ | | Sbjct 116 EGARRTEEDYPNDFSSYLEAKAAKDFIDW#LIK-GQGRRDFAEESREIE 162 |
| Heloderma suspectum, venom, Peptide, 39 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMN 163 | +|||||| || ++ + |++|#| | Sbjct 1 HGEGTFTSDLSKQMEEEAVRLFIEW#LKN 28 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 139 GTFTSDYSKYLDSRRAQDFVQW#LMNTKRNRN 169 ||+||| | || + |++|| |#| + |+ Sbjct 3 GTYTSDVSSYLQDQAAKEFVSW#LKTGRGRRD 33 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQW#LMNTKRNR 168 |+ || ||| | +|+ + ++|+ |#|++ + | Sbjct 1 HADGTLTSDISSFLEKQATKEFIAW#LVSGRGRR 33 |
[Site 4] RAQDFVQWLM162-NTKRNRNNIA
Met162 Asn
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Arg153 | Ala154 | Gln155 | Asp156 | Phe157 | Val158 | Gln159 | Trp160 | Leu161 | Met162 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Asn163 | Thr164 | Lys165 | Arg166 | Asn167 | Arg168 | Asn169 | Asn170 | Ile171 | Ala172 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| DKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSS |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 123.00 | 10 | glucagon, isoform CRA_b |
| 2 | N/A | 79.70 | 45 | 0 |
| 3 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 64.70 | 1 | AAB31092.1 |
| 4 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 61.60 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
| 5 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 60.80 | 1 | glucagon II |
| 6 | Contains: Glucagon; Glucagon-like peptide | 60.10 | 4 | GLUC_AMICA Glucagon precursor |
| 7 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 60.10 | 1 | glucagon |
| 8 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 58.50 | 1 | glucagon G-29 |
| 9 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 57.80 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gb |
| 10 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.20 | 1 | GLUC_LAMFL Glucagon gb |
| 11 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 53.50 | 1 | glucagon |
| 12 | deshis1, Desphe6, Glu9 | 53.50 | 1 | A Chain A, Nmr Solution Structure Of The Glucagon |
| 13 | Monodelphis domestica | 48.90 | 3 | PREDICTED: similar to Gastric inhibitory polypepti |
| 14 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 48.90 | 1 | GLUC1_PETMA Glucagon-1 precursor |
| 15 | Xenopus laevis | 47.00 | 5 | proglucagon II |
| 16 | Hoplobatrachus rugulosus | 46.60 | 1 | AF324209_1 proglucagon |
| 17 | Bufo marinus | 46.60 | 1 | proglucagon |
| 18 | Gallus gallus | 46.20 | 4 | glucagon isoform 1 |
| 19 | Meleagris gallopavo | 46.20 | 2 | preproglucagon B |
| 20 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | 44.70 | 1 | GLUC_HELSU Glucagon precursor |
| 21 | Oncorhynchus tshawytscha | 43.50 | 1 | S78474_1 proglucagon |
| 22 | Ictalurus punctatus | 43.10 | 3 | proglucagon I |
| 23 | Ambloplites rupestris | 43.10 | 1 | proglucagon |
| 24 | Rattus norvegicus | 42.70 | 6 | Glucose-dependent insulinotropic peptide |
| 25 | Canis familiaris | 42.70 | 2 | PREDICTED: similar to Gastric inhibitory polypepti |
| 26 | Capra hircus | 42.70 | 1 | glucagon |
| 27 | Pan troglodytes | 42.40 | 2 | PREDICTED: fibroblast activation protein, alpha su |
| 28 | Xenopus tropicalis | 42.40 | 2 | glucagon |
| 29 | Danio rerio | 42.00 | 6 | hypothetical protein LOC494052 |
| 30 | Bos taurus | 42.00 | 5 | vasoactive intestinal peptide |
| 31 | Squalus acanthias | 41.60 | 1 | proglucagon |
| 32 | Agkistrodon piscivorus | 41.60 | 1 | proglucagon |
| 33 | Macaca mulatta | 41.20 | 3 | PREDICTED: vasoactive intestinal peptide |
| 34 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 41.20 | 1 | glucagon-like peptide, GLP |
| 35 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 41.20 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
| 36 | Sebastes caurinus | 40.80 | 4 | proglucagon I |
| 37 | Heloderma suspectum | 40.80 | 2 | proglucagon |
| 38 | Tetraodon nigroviridis | 40.00 | 3 | unnamed protein product |
| 39 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 40.00 | 2 | GLUC_CARAU Glucagon precursor |
| 40 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
| 41 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
| 42 | Heloderma horridum | 40.00 | 1 | EXE3_HELHO Exendin-3 precursor emb |
| 43 | Mus musculus | 39.70 | 6 | Gastric inhibitory polypeptide |
| 44 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 38.90 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
| 45 | Protopterus dolloi | 38.90 | 1 | proglucagon |
| 46 | Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | 38.10 | 1 | VIP_MOUSE VIP peptides precursor |
| 47 | Arvicanthis ansorgei | 37.40 | 1 | vasoactive intestinal polypeptide |
| 48 | synthetic construct | 37.00 | 1 | Homo sapiens glucagon |
| 49 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 37.00 | 1 | GLUC2_PETMA Glucagon-2 precursor |
| 50 | Phodopus sungorus | 36.60 | 1 | glucagon precursor |
| 51 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 36.60 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
| 52 | Sus scrofa | 36.20 | 1 | glucagon |
| 53 | Neoceratodus forsteri | 36.20 | 1 | proglucagon |
| 54 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 35.80 | 1 | GLUC_LEPSP Glucagon precursor |
| 55 | Canis lupus familiaris | 35.80 | 1 | glucagon |
| 56 | Heloderma suspectum, venom, Peptide, 39 aa | 35.40 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30-V |
| 57 | Hydrolagus colliei | 35.00 | 1 | proglucagon |
| 58 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 34.70 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gb |
| 59 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 34.70 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSD 189 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSD 189 |
| N/A | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIA 172 |||||||||||||||||||||||||||#|||||+|||| Sbjct 1 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNKNNIA 37 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN 167 ||+||||||||||+|+|||+|||||||#+|||| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDFVQWLM#STKRN 32 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 164 |||||||||||||||+||||||+||||#+| Sbjct 1 HSQGTFTSDYSKYLDNRRAQDFIQWLM#ST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN 167 ||+|||++||||||++|||||||||| #|+||| Sbjct 1 HSEGTFSNDYSKYLETRRAQDFVQWLK#NSKRN 32 |
| Contains: Glucagon; Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 164 |||||||+|||||+|+|||||||||||#+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDFVQWLM#ST 29 |
| Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 164 |||||||+|||||+|+|||||||||||#+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDFVQWLM#ST 29 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 164 ||+||||||||||+|+|||+|||||||#+| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDFVQWLM#ST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN 167 ||+|||++||||||+ |+|||||+|||#| ||+ Sbjct 1 HSEGTFSNDYSKYLEDRKAQDFVRWLM#NNKRS 32 |
| Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 164 ||||+|||||||||||++|+||| |||#|| Sbjct 1 HSQGSFTSDYSKYLDSKQAKDFVIWLM#NT 29 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#N 163 ||+|||||||||||++++|+|||+|||#| Sbjct 1 HSEGTFTSDYSKYLENKQAKDFVRWLM#N 28 |
| deshis1, Desphe6, Glu9 | Query 137 SQGTFTSDYSKYLDSRRAQDFVQWLM#NT 164 |||| ||+||||||||||||||||||#|| Sbjct 1 SQGT-TSEYSKYLDSRRAQDFVQWLM#NT 27 |
| Monodelphis domestica | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGT 185 +|+++||| |||| +| |||| ||+#+ | +| + ||+ || |+|| Sbjct 51 QRYAEGTFISDYSITMDKIMQQDFVNWLL#SQKGKKN--SWRHNITERKADGT 100 |
| Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||+|||||||||||++++|+|||+|||#| || + + + |||+||||+|++| Sbjct 41 KRHSEGTFTSDYSKYLENKQAKDFVRWLM#NAKRGGSELQR------RHADGTFTNDMTS 93 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR---NNIAKRHDEFERHAE 183 +||+ ||||+| + |||++ |+||| || # + ++| + + | +|||| Sbjct 80 RRHADGTFTNDMTSYLDAKAARDFVSWLA#RSDKSRRDGGDHLAENSEDKRHAE 132 |
| Xenopus laevis | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 191 |||||||||||||||||||||||||||||#||||+ +++|+ ++||||||||||||+ Sbjct 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRS-GGLSRRNADYERHAEGTFTSDVT 107 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 +||++||+|+| ++||+ + + |++||+# | + + ||||||||+|+++ Sbjct 140 ERHAEGTYTNDVTEYLEEKATKAFIEWLI#KGK-------PKKIRYSRHAEGTFTNDMTN 191 Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRH 175 ||++||||+| + ||+ + |++|| ||+#| + | ++ + | Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEFVGWLI#NGRPKRKDLLEEH 219 |
| Hoplobatrachus rugulosus | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 191 |||||||||||||||||||||||||||||#|+||+ |+||+ +||||||||+|+||+ Sbjct 51 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NSKRS-GGISKRNVQFERHAEGTYTNDVT 107 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 +||++||+|+| +++|+ + |++|+ ||+# | + ++ ||||||||||++| Sbjct 95 ERHAEGTYTNDVTQFLEEKAAKEFIDWLI#KGKPKKQRLS-------RHAEGTFTSDMTS 146 Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFE-RHAEGTFTSD 189 ||++|||||| + ||+ + |++|| ||+# + || +| + |||+|+|||| Sbjct 134 RHAEGTFTSDMTSYLEEKAAKEFVDWLI#KGRPKRNFPDISAEEMDRRHADGSFTSD 189 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 164 |+||+ |+||||++| || + ||+|+ |++#|| Sbjct 178 DRRHADGSFTSDFNKALDIKAAQEFLDWII#NT 209 |
| Bufo marinus | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM--#NTKRNRNNIAKRHDEFERHAEGTFTSD 189 ||++|||||| + +|+ + |++|| ||+ # ||| ++++ | |||+|+|||| Sbjct 62 RHAEGTFTSDMTSFLEEKAAKEFVDWLIKG#RPKRNFSDVSAADDMDRRHADGSFTSD 118 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 +||++||+|+| +++|+ + |++|+ ||+# | |+ ||||||||||++| Sbjct 23 ERHAEGTYTNDVTQFLEEKAAKEFIDWLL#------KGIPKK-QRLSRHAEGTFTSDMTS 74 Query 156 DFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 191 || ||||#|+||+ +++|+ +||||||||+|+||+ Sbjct 1 DFAQWLM#NSKRS-GGMSRRNVQFERHAEGTYTNDVT 35 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NT 164 |+||+ |+||||++| || + ||+|+ |++#|| Sbjct 107 DRRHADGSFTSDFNKALDIKAAQEFLDWII#NT 138 |
| Gallus gallus | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN------------------RNNIAKRH 175 |||||||||||||||||||||||||||||#+|||| | |+||| Sbjct 53 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#STKRNGQQGQEDKENDKFPDQLSSNAISKRH 112 Query 176 DEFERHAEGTFTSDVSS 192 |||||||||+|||++| Sbjct 113 SEFERHAEGTYTSDITS 129 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAK---RHDEFERHAEGTFTSDV 190 +||++||+||| + ||+ + |++|+ ||+#| + |+ | + |||+||||||+ Sbjct 116 ERHAEGTYTSDITSYLEGQAAKEFIAWLV#NGRGRRDFPEKALMAEEMGRRHADGTFTSDI 175 Query 191 S 191 + Sbjct 176 N 176 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNI 171 +||+ |||||| +| || |++|++||+#||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEFLKWLI#NTKVTQRDL 201 |
| Meleagris gallopavo | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN------------------RNNIAKRH 175 |||||||||||||||||||||||||||||#+|||| | |+||| Sbjct 53 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#STKRNGQQGQEDKENDEFPDQLSSNAISKRH 112 Query 176 DEFERHAEGTFTSDVSS 192 |||||||||+|||++| Sbjct 113 SEFERHAEGTYTSDITS 129 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAK---RHDEFERHAEGTFTSDV 190 +||++||+||| + ||+ + |++|+ ||+#| + |+ | + |||+||||||+ Sbjct 116 ERHAEGTYTSDITSYLEGQAAKEFIAWLV#NGRGRRDFPEKALMAEEMGRRHADGTFTSDI 175 Query 191 S 191 + Sbjct 176 N 176 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNI 171 +||+ |||||| +| || |++|++||+#||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEFLKWLI#NTKVTQRDL 201 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKR------------------NRNNIAKRH 175 |||||||||||||||||+|||||||||||#|||| + | +|+ | Sbjct 51 KRHSQGTFTSDYSKYLDTRRAQDFVQWLM#NTKRSGQQGVEEREKENLLDQLSSNGLARHH 110 Query 176 DEFERHAEGTFTSDVSS 192 |+||||+| +|||+|| Sbjct 111 AEYERHADGRYTSDISS 127 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAK---RHDEFERHAEGTFTSD 189 +||+ | +||| | ||+ + |++|+ ||+#| + |+ + + | |||+|||||| Sbjct 114 ERHADGRYTSDISSYLEGQAAKEFIAWLV#NGRGRRDFLEEAGTADDIGRRHADGTFTSD 172 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNI 171 +||+ |||||||++ || |+|++||+#| | + ++ Sbjct 162 RRHADGTFTSDYNQLLDDIATQEFLKWLI#NQKVTQRDL 199 |
| Oncorhynchus tshawytscha | Query 137 SQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 | |||++||||| + | |||||||||#|+||+ +|||+||+|||||+ Sbjct 2 SXGTFSNDYSKYQEERMAQDFVQWLM#NSKRS-------GAPSKRHADGTYTSDVST 50 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 168 |||+ ||+||| | || + |+||| || #+ + | Sbjct 37 KRHADGTYTSDVSTYLQDQAAKDFVSWLK#SGRARR 71 |
| Ictalurus punctatus | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 +|||+|||++||||||++|||||||||||#|+||+ |||+||+|||||| Sbjct 49 RRHSEGTFSNDYSKYLETRRAQDFVQWLM#NSKRS-------DSPARRHADGTYTSDVSS 100 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEF--ERHAEGTFTSDVS 191 +||+ ||+||| | || + |+||+ || #+ + + + | + || +|+|||||+ Sbjct 87 RRHADGTYTSDVSSYLQDQAAKDFITWLK#SGQPKPDAVETRSVDTLRRRHVDGSFTSDVN 146 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRH 175 +|| |+|||| +| ||| |++++||+|#|+ + + ||| Sbjct 134 RRHVDGSFTSDVNKVLDSLAAKEYLQWVM#NSPSSAS--GKRH 173 |
| Ambloplites rupestris | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 |||||||+||+ ||+ |+||||++|||#| | |+ |++ |||+|||| | || Sbjct 1 HSQGTFTNDYTNYLEDRQAQDFIRWLM#NNK--RSGAAEK-----RHADGTFTDDASS 50 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDE--FERHAEGTFTSDV 190 +|||+ |||| | | + +||| | #+ + | | | || ||+||||+ Sbjct 36 EKRHADGTFTDDASSDFYDQAIKDFVAKLK#SGQDRREPETDRRREAFSRRHVEGSFTSDI 95 Query 191 S 191 + Sbjct 96 N 96 |
| Rattus norvegicus | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| | |||| ||+# | +|+ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNWLL#AQKGKKND--WKHNLTQREA 88 |
| Canis familiaris | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| | |||| ||+# | +|+ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNWLL#AQKGKKND--WKHNITQREA 88 |
| Capra hircus | Query 169 NNIAKRHDEFERHAEGTFTSDVSS 192 |||||||||||||||||||||||| Query 169 NNIAKRHDEFERHAEGTFTSDVSS 192 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 168 +||++|||||| | ||+ + |++|+ ||+# + | Sbjct 11 ERHAEGTFTSDVSSYLEGQAAKEFIAWLV#KGRGRR 45 |
| Pan troglodytes | Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||||||||||||||||||||||||||||#||||| +++| ||||||||||||| Sbjct 972 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN-SSVA------YRHAEGTFTSDVSS 1024 Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 168 ||++|||||| | ||+ + |++|+ ||+# + | Sbjct 1012 RHAEGTFTSDVSSYLEGQAAKEFIAWLV#KGRGRR 1045 |
| Xenopus tropicalis | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 191 ||||||||||||||||||||||||+||||#||||+ +++|+ ++||||||||||||+ Sbjct 51 KRHSQGTFTSDYSKYLDSRRAQDFIQWLM#NTKRS-GGLSRRNADYERHAEGTFTSDVT 107 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 +||++||+|+| ++||+ + |++|++||+#| | + + ||||||||+|+++ Sbjct 140 ERHAEGTYTNDVTEYLEEKAAKEFIEWLI#NGK-------PKKIRYSRHAEGTFTNDMTN 191 Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFE---RHAEGTFTSDVS 191 ||++||||+| + ||+ + |++|| ||+# | + | ++ | | |||+|+||+|++ Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEFVGWLI#K-GRPKRNFSEAHSVEEMDRRHADGSFTNDIN 237 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 165 |+||+ |+||+| +| || ||+|+ |++#||+ Sbjct 224 DRRHADGSFTNDINKVLDIIAAQEFLDWVI#NTQ 256 |
| Danio rerio | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||+|||++||||||++|||||||||||#| ||| ++ +||||||+|||||| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDFVQWLM#NAKRNGGSV-------KRHAEGTYTSDVSS 99 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWL 161 |||++||+||| | || + || || || Sbjct 86 KRHAEGTYTSDVSSYLQDQAAQSFVAWL 113 |
| Bos taurus | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSD 189 ||+ | ||||||+ | |+ +++ |+# || |+|++ +||++ || + Sbjct 80 RHADGVFTSDYSRLLGQLSAKKYLESLI#G-KRVSNSISEDQGPIKRHSDAVFTDN 133 |
| Squalus acanthias | Query 150 DSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 |+|||+|||||||#+|||| |+ +||||||+|||| | Sbjct 1 DNRRAKDFVQWLM#STKRN-------GDKTKRHAEGTYTSDVDS 36 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWL--M#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 191 |||++||+||| | +|+ || | #| ++| +|+||| | || ||++ |+| Sbjct 23 KRHAEGTYTSDVDSLSDYFKAKRFVDSLTSY#NKRQNGRSISKRHVESTRHTEGSY-RDIS 81 Query 192 S 192 | Query 192 S 192 Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN---------NIAKRHDEFERHAEGT 185 ||++|++ | | ||+++ |+||+ ||+# + | | + |||+|| Sbjct 71 RHTEGSYR-DISSYLEAKAAKDFINWLI#KGRGRREFPEESKEIVNEVIPEEMDRRHADGT 129 Query 186 FTSDVS 191 |||+++ Sbjct 130 FTSEIN 135 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFE 179 |+||+ |||||+ + ||+ |++|+ |++#|+| | | | | Sbjct 122 DRRHADGTFTSEINIVLDTIAAKEFLNWIL#NSK----TIQSRDSEIE 164 |
| Agkistrodon piscivorus | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRH---DEFERHAEGTFTSD 189 +||+ ||+||| | ||+ + |++|+ ||+#| + |+ | | |||+|||||| Sbjct 34 ERHADGTYTSDISSYLEGQAAKEFIAWLV#NGRGRRDFSEGAHTGEDLGRRHADGTFTSD 92 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNI 171 +||+ |||||||+| || |+|++||+#| | + ++ Sbjct 82 RRHADGTFTSDYNKLLDDIATQEFLKWLI#NQKVTQRDL 119 Query 149 LDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 |+ | ++|+ | #+ | +|+ | |+||||+||+|||+|| Sbjct 9 LEDREKENFLDQLA#S-----NGLARPHAEYERHADGTYTSDISS 47 |
| Macaca mulatta | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSD 189 ||+ | ||||+|| | |+ +++ ||# || +||++ +||++ || + Sbjct 80 RHADGVFTSDFSKLLGQLSAKKYLESLM#G-KRVSSNISEDPVPVKRHSDAVFTDN 133 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRN 167 |+ ||||+| + |||++ |+||| || # + ++ Sbjct 1 HADGTFTNDMTSYLDAKAARDFVSWLA#RSDKS 32 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||+|||++||||||++|||||||||| #|+||| | |||+||+|||||| Sbjct 50 KRHSEGTFSNDYSKYLETRRAQDFVQWLK#NSKRN--------GLFRRHADGTYTSDVSS 100 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWL 161 +||+ ||+||| | || + |+||| || Sbjct 87 RRHADGTYTSDVSSYLQDQAAKDFVSWL 114 |
| Sebastes caurinus | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||+|||++|||+||+ |+|||||+|||#| ||+ || +|||+||||||||| Sbjct 48 KRHSEGTFSNDYSRYLEERKAQDFVRWLM#NNKRS------GADE-KRHADGTFTSDVSS 99 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDE--FERHAEGTFTSDV 190 +|||+ |||||| | || + +||| | #+ + | + + | || +|+||||| Sbjct 85 EKRHADGTFTSDVSSYLKDQAIKDFVNRLK#SGQVRRESETEWRGEAFSRRHVDGSFTSDV 144 Query 191 S 191 + Sbjct 145 N 145 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDE 177 +|| |+|||| +| ||| |++++ |+|# +| + + ++ |+ Sbjct 133 RRHVDGSFTSDVNKVLDSMAAKEYLLWVM#TSKPSGESKKRQEDQ 176 |
| Heloderma suspectum | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKR------------------NRNNIAKRH 175 |||||||||||||||||+|||||||||||#|||| + | +|+ | Sbjct 51 KRHSQGTFTSDYSKYLDTRRAQDFVQWLM#NTKRSGQQGVEEREKENLLDQLSSNGLARHH 110 Query 176 DEFERHAEGTFTSDVSS 192 |+||||+| +|||+|| Sbjct 111 AEYERHADGRYTSDISS 127 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 168 +||+ | +||| | ||+ + |++|+ ||+#| + | Sbjct 114 ERHADGRYTSDISSYLEGQAAKEFIAWLV#NGRGRR 148 |
| Tetraodon nigroviridis | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||+|||++||||||++|||||||||| #|+||| + | |||+||+|||||+ Sbjct 787 KRHSEGTFSNDYSKYLETRRAQDFVQWLK#NSKRNGS-------LFRRHADGTYTSDVSA 838 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 168 +||+ ||+||| | || + |++|| || # + | Sbjct 825 RRHADGTYTSDVSAYLQDQAAKEFVSWLK#TGRGRR 859 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||+|||++||||||++|||||||+|||#|+| | + +||||||+|||+|| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDFVEWLM#NSKSNGGSA-------KRHAEGTYTSDISS 99 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWL 161 |||++||+||| | +| + ||+|| || Sbjct 86 KRHAEGTYTSDISSFLRDQAAQNFVAWL 113 |
| Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 || |+|||++ |||| + | |+||+ |||#|+||+ +|||+||+|||||+ Sbjct 50 KRQSEGTFSNYYSKYQEERMARDFLHWLM#NSKRS-------GAPSKRHADGTYTSDVST 101 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHD--EFERHAEGTFTSDVS 191 |||+ ||+||| | || + |+||| || #+ | + + + || +|+|||||+ Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDFVSWLK#SGPARRESAEESMNGPMSRRHVDGSFTSDVN 147 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHD 176 +|| |+|||| +| ||| |++++ |+|# +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEYLLWVM#TSKTSGKSNKRQED 177 |
| Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||+|||++||||| + | |||||||||#|+||+ +|||+||+|||||+ Sbjct 50 KRHSEGTFSNDYSKYQEERMAQDFVQWLM#NSKRS-------GAPSKRHADGTYTSDVST 101 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNI--AKRHDEFERHAEGTFTSDVS 191 |||+ ||+||| | || + |+||| || #+ + | + ++ || +|+|||||+ Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDFVSWLK#SGRARRESAEESRNGPMSRRHVDGSFTSDVN 147 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHD 176 +|| |+|||| +| ||| |++++ |+|# +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEYLLWVM#TSKTSGKSNKRQED 177 |
| Heloderma horridum | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#N 163 |||| |||||| || ++ + |++|| #| Sbjct 46 KRHSDGTFTSDLSKQMEEEAVRLFIEWLK#N 75 |
| Mus musculus | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| | |||| ||+# + +++ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKIRQQDFVNWLL#AQRGKKSD--WKHNITQREA 88 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 165 |+ |+|||| +| ||+ |++|+ ||+#+|| Sbjct 1 HADGSFTSDINKVLDTIAAKEFLNWLI#STK 30 |
| Protopterus dolloi | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 |||||||| |||+| |+++ | | || ||#+||| ++|||+| |||||||+|||+|| Sbjct 30 KRHSQGTFMSDYAKLLEAKHALDLVQRLM#STKRT-GAVSKRHNEIERHAEGTYTSDISS 87 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFE-RHAEGTFTSDVSS 192 +||++||+||| | ||+ + +|++|||# + |+ +| + |||+|| |||++| Sbjct 74 ERHAEGTYTSDISSYLEGQAVNEFIRWLM#KGRGRRDFSETDIEEMDRRHADGTVTSDINS 133 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 165 |+||+ || ||| + |+| ++|+ ||+#| | Sbjct 119 DRRHADGTVTSDINSVLESIATREFLNWLI#NAK 151 |
| Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSD 189 ||+ | ||||||+ | |+ +++ |+# || ++|++ +||++ || + Sbjct 80 RHADGVFTSDYSRLLGQISAKKYLESLI#G-KRISSSISEDPVPIKRHSDAVFTDN 133 |
| Arvicanthis ansorgei | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSD 189 ||+ | ||||||+ | |+ +++ |+# || ++| + +||++ || + Sbjct 63 RHADGVFTSDYSRLLGQISAKKYLESLI#G-KRISSSILEDPVPIKRHSDAVFTDN 116 |
| synthetic construct | Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN---NIAKRHDEFERHAEGTFTSDV 190 +||++|||||| | ||+ + |++|+ ||+# + |+ +| + |||+|+|+ ++ Sbjct 96 ERHAEGTFTSDVSSYLEGQAAKEFIAWLV#KGRGRRDFPEEVAIVEELGRRHADGSFSDEM 155 Query 191 SS 192 ++ Sbjct 156 NT 157 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 165 +||+ |+|+ + + ||+ |+||+ ||+# || Sbjct 144 RRHADGSFSDEMNTILDNLAARDFINWLI#QTK 175 |
| Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 135 RHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVS 191 |||||+|||||||+|| ++|+||| ||+#|||| + + +||++|+||+|++ Sbjct 43 RHSQGSFTSDYSKHLDVKQAKDFVTWLL#NTKRRGVDAQAGANLEKRHSDGSFTNDMN 99 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKR 166 +|||| |+||+| + || |++|++|| # | Sbjct 86 EKRHSDGSFTNDMNVMLDRMSAKNFLEWLK#QQGR 119 |
| Phodopus sungorus | Query 139 GTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN---NIAKRHDEFERHAEGTFTSDVSS 192 |||||| | ||+ + |++|+ ||+# + |+ + + |||+|+|+ ++++ Sbjct 1 GTFTSDVSSYLEGQAAKEFIAWLV#KGRGRRDFPEEVTIVEELGRRHADGSFSDEMNT 57 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 165 +||+ |+|+ + + ||| +||+ ||+# || Sbjct 44 RRHADGSFSDEMNTILDSLATRDFINWLI#QTK 75 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||+|||++||||||+ |+||+||+|||#| | |+ +|++ |||+||||||||| Sbjct 51 KRHSEGTFSNDYSKYLEDRKAQEFVRWLM#NNK--RSGVAEK-----RHADGTFTSDVSS 102 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWL 161 +|||+ |||||| | || + +||| | Sbjct 88 EKRHADGTFTSDVSSYLKDQAIKDFVDRL 116 |
| Sus scrofa | Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||||||||||||||||||||||||||||#|||||+|||||||||||||||||||||||| Sbjct 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNKNNIAKRHDEFERHAEGTFTSDVSS 109 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN---NIAKRHDEFERHAEGTFTSDV 190 +||++|||||| | ||+ + |++|+ ||+# + |+ + + |||+|+|+ ++ Sbjct 96 ERHAEGTFTSDVSSYLEGQAAKEFIAWLV#KGRGRRDFPEEVTIVEELRRRHADGSFSDEM 155 Query 191 SS 192 ++ Sbjct 156 NT 157 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 165 +||+ |+|+ + + ||+ +||+ ||+#+|| Sbjct 144 RRHADGSFSDEMNTVLDNLATRDFINWLL#HTK 175 |
| Neoceratodus forsteri | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 |||||||| |||+| |++| | |||| ||#||||| ++||| | |||||||+|||+|| Sbjct 22 KRHSQGTFMSDYAKLLEARHALDFVQRLM#NTKRN-GGVSKRHSEIERHAEGTYTSDISS 79 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEF-ERHAEGTFTSDVSS 192 +||++||+||| | ||+ + | +||+||+# + |+ +| |||+|| |+|+++ Sbjct 66 ERHAEGTYTSDISSYLEGQAANEFVRWLL#KGRGRRDFSDTDAEEMGRRHADGTITNDMNN 125 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 165 +||+ || |+| + |+| ++|+ ||+#|+| Sbjct 112 RRHADGTITNDMNNVLESIATREFLNWLI#NSK 143 |
| Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 |||||||+|||||||+|||||||||||#+|||+ | ||+||+|||||| Sbjct 1 HSQGTFTNDYSKYLDTRRAQDFVQWLM#STKRS-GGITXXXXXXXXHADGTYTSDVSS 56 Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 168 |+ ||+||| | || + |+ || || # + | Sbjct 45 HADGTYTSDVSSYLQDQAAKKFVTWLK#QGQDRR 77 |
| Canis lupus familiaris | Query 133 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 ||||||||||||||||||||||||||||||#|||||+|||||||||||||||||||||||| Sbjct 50 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNKNNIAKRHDEFERHAEGTFTSDVSS 109 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN---NIAKRHDEFERHAEGTFTSDV 190 +||++|||||| | ||+ + |++|+ ||+# + |+ +| + |||+|+|+ ++ Sbjct 96 ERHAEGTFTSDVSSYLEGQAAKEFIAWLV#KGRGRRDFPEEVAIVEEFRRRHADGSFSDEM 155 Query 191 SS 192 ++ Sbjct 156 NT 157 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTK 165 +||+ |+|+ + + ||+ +||+ ||+# || Sbjct 144 RRHADGSFSDEMNTVLDTLATRDFINWLL#QTK 175 |
| Heloderma suspectum, venom, Peptide, 39 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#N 163 | +|||||| || ++ + |++|| #| Sbjct 1 HGEGTFTSDLSKQMEEEAVRLFIEWLK#N 28 |
| Hydrolagus colliei | Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFERHAEGTFTSDVSS 192 |||+ | |+||||||||+|| +||||||+#+|||| | |+ +|||+| +||||+| Sbjct 30 KRHTDGIFSSDYSKYLDNRRTKDFVQWLL#STKRNGANT----DKTKRHADGIYTSDVAS 84 Query 134 KRHSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRNN--IAKRHDEFERHAEGTFTSDVS 191 |||+ | +||| + | +++ ||+ | #| + +|+ ++||| | | | + +| | Sbjct 71 KRHADGIYTSDVASLTDYLKSKRFVESLS#NYNKRQNDRRMSKRHVEGARRTEEDYPNDFS 130 Query 192 S 192 | Query 192 S 192 Query 134 KRHSQGT------FTSDYSKYLDSRRAQDFVQWLM#NTKRNRNNIAKRHDEFE 179 ||| +| + +|+| ||+++ |+||+ ||+# + | + |+ | | Sbjct 112 KRHVEGARRTEEDYPNDFSSYLEAKAAKDFIDWLI#K-GQGRRDFAEESREIE 162 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 139 GTFTSDYSKYLDSRRAQDFVQWLM#NTKRNRN 169 ||+||| | || + |++|| || # + |+ Sbjct 3 GTYTSDVSSYLQDQAAKEFVSWLK#TGRGRRD 33 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDFVQWLM#NTKRNR 168 |+ || ||| | +|+ + ++|+ ||+#+ + | Sbjct 1 HADGTLTSDISSFLEKQATKEFIAWLV#SGRGRR 33 |
[Site 5] YLDSRRAQDF157-VQWLMNTKRN
Phe157 Val
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Tyr148 | Leu149 | Asp150 | Ser151 | Arg152 | Arg153 | Ala154 | Gln155 | Asp156 | Phe157 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Val158 | Gln159 | Trp160 | Leu161 | Met162 | Asn163 | Thr164 | Lys165 | Arg166 | Asn167 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| DQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFT |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 129.00 | 10 | glucagon, isoform CRA_b |
| 2 | N/A | 79.70 | 44 | 0 |
| 3 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | 64.70 | 1 | AAB31092.1 |
| 4 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | 61.60 | 1 | glucagon=proglucagon-derived 3.5 kda peptide |
| 5 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | 60.80 | 1 | glucagon II |
| 6 | Contains: Glucagon; Glucagon-like peptide | 60.10 | 4 | GLUC_AMICA Glucagon precursor |
| 7 | Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | 60.10 | 1 | glucagon |
| 8 | Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | 58.50 | 1 | glucagon G-29 |
| 9 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | 57.80 | 1 | GLUC1_ORENI Glucagon-1 (Glucagon I) gb |
| 10 | Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | 56.20 | 1 | GLUC_LAMFL Glucagon gb |
| 11 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | 53.50 | 1 | glucagon |
| 12 | deshis1, Desphe6, Glu9 | 53.50 | 1 | A Chain A, Nmr Solution Structure Of The Glucagon |
| 13 | Monodelphis domestica | 48.90 | 3 | PREDICTED: similar to Gastric inhibitory polypepti |
| 14 | Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | 48.90 | 1 | GLUC1_PETMA Glucagon-1 precursor |
| 15 | Xenopus laevis | 47.00 | 5 | proglucagon II |
| 16 | Hoplobatrachus rugulosus | 46.60 | 1 | AF324209_1 proglucagon |
| 17 | Gallus gallus | 46.20 | 4 | glucagon isoform 1 |
| 18 | Meleagris gallopavo | 46.20 | 2 | preproglucagon B |
| 19 | Bufo marinus | 44.70 | 1 | proglucagon |
| 20 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | 44.70 | 1 | GLUC_HELSU Glucagon precursor |
| 21 | Capra hircus | 43.90 | 1 | glucagon |
| 22 | Oncorhynchus tshawytscha | 43.50 | 1 | S78474_1 proglucagon |
| 23 | Ictalurus punctatus | 43.10 | 3 | proglucagon I |
| 24 | Rattus norvegicus | 42.70 | 5 | Glucose-dependent insulinotropic peptide |
| 25 | Canis familiaris | 42.70 | 2 | PREDICTED: similar to Gastric inhibitory polypepti |
| 26 | Xenopus tropicalis | 42.40 | 2 | glucagon |
| 27 | Pan troglodytes | 42.40 | 2 | PREDICTED: fibroblast activation protein, alpha su |
| 28 | Danio rerio | 42.00 | 6 | hypothetical protein LOC494052 |
| 29 | Bos taurus | 42.00 | 5 | vasoactive intestinal peptide |
| 30 | Macaca mulatta | 41.60 | 3 | PREDICTED: vasoactive intestinal peptide |
| 31 | Heloderma suspectum | 41.60 | 2 | proglucagon |
| 32 | Squalus acanthias | 41.60 | 1 | proglucagon |
| 33 | Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | 41.20 | 1 | glucagon-like peptide, GLP |
| 34 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | 41.20 | 1 | GLUC2_LOPAM Glucagon-2 precursor (Glucagon II) |
| 35 | Sebastes caurinus | 40.80 | 4 | proglucagon I |
| 36 | Tetraodon nigroviridis | 40.00 | 3 | unnamed protein product |
| 37 | Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | 40.00 | 2 | GLUC_CARAU Glucagon precursor |
| 38 | Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC1_ONCMY Glucagon-1 precursor (Glucagon I) |
| 39 | Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | 40.00 | 1 | GLUC2_ONCMY Glucagon-2 precursor (Glucagon II) |
| 40 | Heloderma horridum | 40.00 | 1 | EXE3_HELHO Exendin-3 precursor emb |
| 41 | Mus musculus | 39.70 | 6 | Gastric inhibitory polypeptide |
| 42 | Protopterus dolloi | 38.90 | 1 | proglucagon |
| 43 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | 38.90 | 1 | glucagon-like peptide-2, GLP-2=proglucagon-derived |
| 44 | Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | 38.50 | 1 | VIP_MOUSE VIP peptides precursor |
| 45 | Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | 38.10 | 1 | GLUC2_PETMA Glucagon-2 precursor |
| 46 | Ambloplites rupestris | 37.70 | 1 | proglucagon |
| 47 | Arvicanthis ansorgei | 37.70 | 1 | vasoactive intestinal polypeptide |
| 48 | synthetic construct | 37.00 | 1 | Homo sapiens glucagon |
| 49 | Phodopus sungorus | 36.60 | 1 | glucagon precursor |
| 50 | Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | 36.60 | 1 | GLUC1_LOPAM Glucagon-1 precursor (Glucagon I) |
| 51 | Sus scrofa | 36.20 | 1 | glucagon |
| 52 | Neoceratodus forsteri | 36.20 | 1 | proglucagon |
| 53 | Canis lupus familiaris | 35.80 | 1 | glucagon |
| 54 | Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | 35.80 | 1 | GLUC_LEPSP Glucagon precursor |
| 55 | Hydrolagus colliei | 35.40 | 1 | proglucagon |
| 56 | Heloderma suspectum, venom, Peptide, 39 aa | 35.40 | 1 | A Chain A, Solution Structure Of Exendin-4 In 30-V |
| 57 | Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | 34.70 | 1 | GLUC2_ORENI Glucagon-2 (Glucagon II) gb |
| 58 | Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | 34.70 | 1 | glucagon-like peptide-1, GLP-1=proglucagon-derived |
| 59 | Agkistrodon piscivorus | 33.50 | 1 | proglucagon |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 |
| N/A | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIA 172 ||||||||||||||||||||||#||||||||||+|||| Sbjct 1 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNKNNIA 37 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN 167 ||+||||||||||+|+|||+||#|||||+|||| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDF#VQWLMSTKRN 32 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 164 |||||||||||||||+||||||#+||||+| Sbjct 1 HSQGTFTSDYSKYLDNRRAQDF#IQWLMST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN 167 ||+|||++||||||++||||||#|||| |+||| Sbjct 1 HSEGTFSNDYSKYLETRRAQDF#VQWLKNSKRN 32 |
| Contains: Glucagon; Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 164 |||||||+|||||+|+||||||#|||||+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDF#VQWLMST 29 |
| Amia calva=bowfin, pancreatic tissues, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 164 |||||||+|||||+|+||||||#|||||+| Sbjct 1 HSQGTFTNDYSKYMDTRRAQDF#VQWLMST 29 |
| Scyliorhinus canicula=European common dogfish, pancreas, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 164 ||+||||||||||+|+|||+||#|||||+| Sbjct 1 HSEGTFTSDYSKYMDNRRAKDF#VQWLMST 29 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 36 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN 167 ||+|||++||||||+ |+||||#|+|||| ||+ Sbjct 1 HSEGTFSNDYSKYLEDRKAQDF#VRWLMNNKRS 32 |
| Lampetra fluviatilis=river lamprey, small intestine, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 164 ||||+|||||||||||++|+||#| ||||| Sbjct 1 HSQGSFTSDYSKYLDSKQAKDF#VIWLMNT 29 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 29 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMN 163 ||+|||||||||||++++|+||#|+|||| Sbjct 1 HSEGTFTSDYSKYLENKQAKDF#VRWLMN 28 |
| deshis1, Desphe6, Glu9 | Query 137 SQGTFTSDYSKYLDSRRAQDF#VQWLMNT 164 |||| ||+|||||||||||||#||||||| Sbjct 1 SQGT-TSEYSKYLDSRRAQDF#VQWLMNT 27 |
| Monodelphis domestica | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGT 185 +|+++||| |||| +| |||#| ||++ | +| + ||+ || |+|| Sbjct 51 QRYAEGTFISDYSITMDKIMQQDF#VNWLLSQKGKKN--SWRHNITERKADGT 100 |
| Contains: Glucagon-1 (Glucagon I); Glucagon-like peptide 1-I (GLP-1I); Glucagon-like peptide 2-I (GLP-2I) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||+|||||||||||++++|+||#|+|||| || + + + |||+|||| Sbjct 41 KRHSEGTFTSDYSKYLENKQAKDF#VRWLMNAKRGGSELQR------RHADGTFT 88 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR---NNIAKRHDEFERHAE 183 +||+ ||||+| + |||++ |+||#| || + ++| + + | +|||| Sbjct 80 RRHADGTFTNDMTSYLDAKAARDF#VSWLARSDKSRRDGGDHLAENSEDKRHAE 132 |
| Xenopus laevis | Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 +|+ | ||||||||||||||||||||||||#|||||||||+ +++|+ ++||||||||| Sbjct 45 EQLKEVKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRS-GGLSRRNADYERHAEGTFT 103 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 | +||++||+|+| ++||+ + + |#++||+ | + + |||||||| Sbjct 138 EIERHAEGTYTNDVTEYLEEKATKAF#IEWLIKGK-------PKKIRYSRHAEGTFT 186 Query 135 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRH 175 ||++||||+| + ||+ + |++|#| ||+| + | ++ + | Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEF#VGWLINGRPKRKDLLEEH 219 |
| Hoplobatrachus rugulosus | Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 | || ||||||||||||||||||||||||#||||||+||+ |+||+ +||||||||+| Sbjct 45 DHHNEVKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNSKRS-GGISKRNVQFERHAEGTYT 103 Query 135 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFE-RHAEGTFT 187 ||++|||||| + ||+ + |++|#| ||+ + || +| + |||+|+|| Sbjct 134 RHAEGTFTSDMTSYLEEKAAKEF#VDWLIKGRPKRNFPDISAEEMDRRHADGSFT 187 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 +||++||+|+| +++|+ + |++|#+ ||+ | + ++ |||||||| Sbjct 95 ERHAEGTYTNDVTQFLEEKAAKEF#IDWLIKGKPKKQRLS-------RHAEGTFT 141 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 164 |+||+ |+||||++| || + ||+|#+ |++|| Sbjct 178 DRRHADGSFTSDFNKALDIKAAQEF#LDWIINT 209 |
| Gallus gallus | Query 129 QMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN------------------RNN 170 |+|| ||||||||||||||||||||||||#|||||+|||| | Sbjct 48 QLNEVKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMSTKRNGQQGQEDKENDKFPDQLSSNA 107 Query 171 IAKRHDEFERHAEGTFT 187 |+||| |||||||||+| Sbjct 108 ISKRHSEFERHAEGTYT 124 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAK---RHDEFERHAEGTFT 187 +| +||++||+||| + ||+ + |++|#+ ||+| + |+ | + |||+|||| Sbjct 113 SEFERHAEGTYTSDITSYLEGQAAKEF#IAWLVNGRGRRDFPEKALMAEEMGRRHADGTFT 172 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNI 171 +||+ |||||| +| || |++|#++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEF#LKWLINTKVTQRDL 201 |
| Meleagris gallopavo | Query 129 QMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN------------------RNN 170 |+|| ||||||||||||||||||||||||#|||||+|||| | Sbjct 48 QLNEVKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMSTKRNGQQGQEDKENDEFPDQLSSNA 107 Query 171 IAKRHDEFERHAEGTFT 187 |+||| |||||||||+| Sbjct 108 ISKRHSEFERHAEGTYT 124 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAK---RHDEFERHAEGTFT 187 +| +||++||+||| + ||+ + |++|#+ ||+| + |+ | + |||+|||| Sbjct 113 SEFERHAEGTYTSDITSYLEGQAAKEF#IAWLVNGRGRRDFPEKALMAEEMGRRHADGTFT 172 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNI 171 +||+ |||||| +| || |++|#++||+||| + ++ Sbjct 164 RRHADGTFTSDINKILDDMAAKEF#LKWLINTKVTQRDL 201 |
| Bufo marinus | Query 135 RHSQGTFTSDYSKYLDSRRAQDF#VQWLM--NTKRNRNNIAKRHDEFERHAEGTFT 187 ||++|||||| + +|+ + |++|#| ||+ ||| ++++ | |||+|+|| Sbjct 62 RHAEGTFTSDMTSFLEEKAAKEF#VDWLIKGRPKRNFSDVSAADDMDRRHADGSFT 116 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 +||++||+|+| +++|+ + |++|#+ ||+ | |+ |||||||| Sbjct 23 ERHAEGTYTNDVTQFLEEKAAKEF#IDWLL------KGIPKK-QRLSRHAEGTFT 69 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNT 164 |+||+ |+||||++| || + ||+|#+ |++|| Sbjct 107 DRRHADGSFTSDFNKALDIKAAQEF#LDWIINT 138 Query 156 DF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||# |||||+||+ +++|+ +||||||||+| Sbjct 1 DF#AQWLMNSKRS-GGMSRRNVQFERHAEGTYT 31 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide 1 (GLP-1); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2) | Query 129 QMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKR------------------NRNN 170 |+|| |||||||||||||||||+||||||#||||||||| + | Sbjct 46 QLNEVKRHSQGTFTSDYSKYLDTRRAQDF#VQWLMNTKRSGQQGVEEREKENLLDQLSSNG 105 Query 171 IAKRHDEFERHAEGTFT 187 +|+ | |+||||+| +| Sbjct 106 LARHHAEYERHADGRYT 122 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAK---RHDEFERHAEGTFT 187 | +||+ | +||| | ||+ + |++|#+ ||+| + |+ + + | |||+|||| Sbjct 112 EYERHADGRYTSDISSYLEGQAAKEF#IAWLVNGRGRRDFLEEAGTADDIGRRHADGTFT 170 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNI 171 +||+ |||||||++ || |+|#++||+| | + ++ Sbjct 162 RRHADGTFTSDYNQLLDDIATQEF#LKWLINQKVTQRDL 199 |
| Capra hircus | Query 169 NNIAKRHDEFERHAEGTFT 187 ||||||||||||||||||| Query 169 NNIAKRHDEFERHAEGTFT 187 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 168 +| +||++|||||| | ||+ + |++|#+ ||+ + | Sbjct 8 DEFERHAEGTFTSDVSSYLEGQAAKEF#IAWLVKGRGRR 45 |
| Oncorhynchus tshawytscha | Query 137 SQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 | |||++||||| + | ||||#||||||+||+ +|||+||+| Sbjct 2 SXGTFSNDYSKYQEERMAQDF#VQWLMNSKRS-------GAPSKRHADGTYT 45 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 168 |||+ ||+||| | || + |+||#| || + + | Sbjct 37 KRHADGTYTSDVSTYLQDQAAKDF#VSWLKSGRARR 71 |
| Ictalurus punctatus | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 +|||+|||++||||||++||||||#||||||+||+ |||+||+| Sbjct 49 RRHSEGTFSNDYSKYLETRRAQDF#VQWLMNSKRS-------DSPARRHADGTYT 95 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEF--ERHAEGTFT 187 +||+ ||+||| | || + |+||#+ || + + + + | + || +|+|| Sbjct 87 RRHADGTYTSDVSSYLQDQAAKDF#ITWLKSGQPKPDAVETRSVDTLRRRHVDGSFT 142 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRH 175 +|| |+|||| +| ||| |+++#+||+||+ + + ||| Sbjct 134 RRHVDGSFTSDVNKVLDSLAAKEY#LQWVMNSPSSAS--GKRH 173 |
| Rattus norvegicus | Query 135 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| | |||#| ||+ | +|+ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKIRQQDF#VNWLLAQKGKKND--WKHNLTQREA 88 |
| Canis familiaris | Query 135 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| | |||#| ||+ | +|+ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKIRQQDF#VNWLLAQKGKKND--WKHNITQREA 88 |
| Xenopus tropicalis | Query 129 QMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 |+ | ||||||||||||||||||||||||#+||||||||+ +++|+ ++||||||||| Sbjct 46 QLKEVKRHSQGTFTSDYSKYLDSRRAQDF#IQWLMNTKRS-GGLSRRNADYERHAEGTFT 103 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 +||++|||||| +++|| + |++|#+ ||+| ++ |++|+ + |||||||+| Sbjct 95 ERHAEGTFTSDVTQHLDEKAAKEF#IDWLINGGPSKEIISRRNADVERHAEGTYT 148 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 +||++||+|+| ++||+ + |++|#++||+| | + + |||||||| Sbjct 140 ERHAEGTYTNDVTEYLEEKAAKEF#IEWLINGK-------PKKIRYSRHAEGTFT 186 Query 135 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFE---RHAEGTFT 187 ||++||||+| + ||+ + |++|#| ||+ | + | ++ | | |||+|+|| Sbjct 179 RHAEGTFTNDMTNYLEEKAAKEF#VGWLIK-GRPKRNFSEAHSVEEMDRRHADGSFT 233 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 165 |+||+ |+||+| +| || ||+|#+ |++||+ Sbjct 224 DRRHADGSFTNDINKVLDIIAAQEF#LDWVINTQ 256 |
| Pan troglodytes | Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||||||||||||||||||||||||||||#|||||||||| +++| |||||||| Sbjct 967 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN-SSVA------YRHAEGTFT 1019 Query 135 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 168 ||++|||||| | ||+ + |++|#+ ||+ + | Sbjct 1012 RHAEGTFTSDVSSYLEGQAAKEF#IAWLVKGRGRR 1045 |
| Danio rerio | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||+|||++||||||++||||||#|||||| ||| ++ +||||||+| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDF#VQWLMNAKRNGGSV-------KRHAEGTYT 94 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWL 161 |||++||+||| | || + || |#| || Sbjct 86 KRHAEGTYTSDVSSYLQDQAAQSF#VAWL 113 |
| Bos taurus | Query 130 MNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ++ + ||+ | ||||||+ | |+ +#++ |+ || |+|++ +||++ || Sbjct 75 VSRNVRHADGVFTSDYSRLLGQLSAKKY#LESLIG-KRVSNSISEDQGPIKRHSDAVFT 131 |
| Macaca mulatta | Query 130 MNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ++ + ||+ | ||||+|| | |+ +#++ || || +||++ +||++ || Sbjct 75 VSRNARHADGVFTSDFSKLLGQLSAKKY#LESLMG-KRVSSNISEDPVPVKRHSDAVFT 131 |
| Heloderma suspectum | Query 129 QMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKR------------------NRNN 170 |+|| |||||||||||||||||+||||||#||||||||| + | Sbjct 46 QLNEVKRHSQGTFTSDYSKYLDTRRAQDF#VQWLMNTKRSGQQGVEEREKENLLDQLSSNG 105 Query 171 IAKRHDEFERHAEGTFT 187 +|+ | |+||||+| +| Sbjct 106 LARHHAEYERHADGRYT 122 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 168 | +||+ | +||| | ||+ + |++|#+ ||+| + | Sbjct 112 EYERHADGRYTSDISSYLEGQAAKEF#IAWLVNGRGRR 148 |
| Squalus acanthias | Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWL--MNTKRNRNNIAKRHDEFERHAEGTF 186 ++ |||++||+||| | +|+ |#| | | ++| +|+||| | || ||++ Sbjct 20 DKTKRHAEGTYTSDVDSLSDYFKAKRF#VDSLTSYNKRQNGRSISKRHVESTRHTEGSY 77 Query 150 DSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 |+|||+||#|||||+|||| |+ +||||||+| Sbjct 1 DNRRAKDF#VQWLMSTKRN-------GDKTKRHAEGTYT 31 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN---------NIAKRHDEFERHA 182 | ||++|++ | | ||+++ |+||#+ ||+ + | | + ||| Sbjct 68 ESTRHTEGSYR-DISSYLEAKAAKDF#INWLIKGRGRREFPEESKEIVNEVIPEEMDRRHA 126 Query 183 EGTFT 187 +|||| Sbjct 127 DGTFT 131 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFE 179 |+||+ |||||+ + ||+ |++|#+ |++|+| | | | | Sbjct 122 DRRHADGTFTSEINIVLDTIAAKEF#LNWILNSK----TIQSRDSEIE 164 |
| Petromyzon marinus=sea lampreys, intestine, parasitic phase, Peptide, 32 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRN 167 |+ ||||+| + |||++ |+||#| || + ++ Sbjct 1 HADGTFTNDMTSYLDAKAARDF#VSWLARSDKS 32 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-2 (Glucagon II); Glucagon-like peptide 2 (Glucagon-like peptide II) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||+|||++||||||++||||||#|||| |+||| | |||+||+| Sbjct 50 KRHSEGTFSNDYSKYLETRRAQDF#VQWLKNSKRN--------GLFRRHADGTYT 95 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWL 161 +||+ ||+||| | || + |+||#| || Sbjct 87 RRHADGTYTSDVSSYLQDQAAKDF#VSWL 114 |
| Sebastes caurinus | Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 |+++ ||||+|||++|||+||+ |+||||#|+|||| ||+ || +|||+|||| Sbjct 42 DELSNMKRHSEGTFSNDYSRYLEERKAQDF#VRWLMNNKRS------GADE-KRHADGTFT 94 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDE--FERHAEGTFT 187 ++|||+ |||||| | || + +||#| | + + | + + | || +|+|| Sbjct 84 DEKRHADGTFTSDVSSYLKDQAIKDF#VNRLKSGQVRRESETEWRGEAFSRRHVDGSFT 141 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDE 177 +|| |+|||| +| ||| |+++#+ |+| +| + + ++ |+ Sbjct 133 RRHVDGSFTSDVNKVLDSMAAKEY#LLWVMTSKPSGESKKRQEDQ 176 |
| Tetraodon nigroviridis | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||+|||++||||||++||||||#|||| |+||| + | |||+||+| Sbjct 787 KRHSEGTFSNDYSKYLETRRAQDF#VQWLKNSKRNGS-------LFRRHADGTYT 833 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 168 +||+ ||+||| | || + |++|#| || + | Sbjct 825 RRHADGTYTSDVSAYLQDQAAKEF#VSWLKTGRGRR 859 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon; Glucagon-like peptide | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||+|||++||||||++||||||#|+||||+| | + +||||||+| Sbjct 48 KRHSEGTFSNDYSKYLETRRAQDF#VEWLMNSKSNGGSA-------KRHAEGTYT 94 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWL 161 |||++||+||| | +| + ||+|#| || Sbjct 86 KRHAEGTYTSDISSFLRDQAAQNF#VAWL 113 |
| Contains: Glicentin-related polypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||+|||++||||| + | ||||#||||||+||+ +|||+||+| Sbjct 50 KRHSEGTFSNDYSKYQEERMAQDF#VQWLMNSKRS-------GAPSKRHADGTYT 96 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNI--AKRHDEFERHAEGTFT 187 |||+ ||+||| | || + |+||#| || + + | + ++ || +|+|| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDF#VSWLKSGRARRESAEESRNGPMSRRHVDGSFT 143 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHD 176 +|| |+|||| +| ||| |+++#+ |+| +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEY#LLWVMTSKTSGKSNKRQED 177 |
| Contains: Glicentin-related polypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2) | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 || |+|||++ |||| + | |+||#+ ||||+||+ +|||+||+| Sbjct 50 KRQSEGTFSNYYSKYQEERMARDF#LHWLMNSKRS-------GAPSKRHADGTYT 96 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHD--EFERHAEGTFT 187 |||+ ||+||| | || + |+||#| || + | + + + || +|+|| Sbjct 88 KRHADGTYTSDVSTYLQDQAAKDF#VSWLKSGPARRESAEESMNGPMSRRHVDGSFT 143 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHD 176 +|| |+|||| +| ||| |+++#+ |+| +| + + ++ | Sbjct 135 RRHVDGSFTSDVNKVLDSLAAKEY#LLWVMTSKTSGKSNKRQED 177 |
| Heloderma horridum | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMN 163 |||| |||||| || ++ + |#++|| | Sbjct 46 KRHSDGTFTSDLSKQMEEEAVRLF#IEWLKN 75 |
| Mus musculus | Query 135 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHA 182 |+++||| |||| +| | |||#| ||+ + +++ +|+ +| | Sbjct 43 RYAEGTFISDYSIAMDKIRQQDF#VNWLLAQRGKKSD--WKHNITQREA 88 |
| Protopterus dolloi | Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 | |||||||| |||+| |+++ | | #|| ||+||| ++|||+| |||||||+| Sbjct 28 EAKRHSQGTFMSDYAKLLEAKHALDL#VQRLMSTKRT-GAVSKRHNEIERHAEGTYT 82 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFE-RHAEGTFT 187 || +||++||+||| | ||+ + +|#++||| + |+ +| + |||+|| | Sbjct 71 NEIERHAEGTYTSDISSYLEGQAVNEF#IRWLMKGRGRRDFSETDIEEMDRRHADGTVT 128 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 165 |+||+ || ||| + |+| ++|#+ ||+| | Sbjct 119 DRRHADGTVTSDINSVLESIATREF#LNWLINAK 151 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 33 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 165 |+ |+|||| +| ||+ |++|#+ ||++|| Sbjct 1 HADGSFTSDINKVLDTIAAKEF#LNWLISTK 30 |
| Contains: Intestinal peptide PHI-42; Intestinal peptide PHI-27 (Peptide histidine isoleucinamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide) | Query 130 MNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ++ + ||+ | ||||||+ | |+ +#++ |+ || ++|++ +||++ || Sbjct 75 VSRNARHADGVFTSDYSRLLGQISAKKY#LESLIG-KRISSSISEDPVPIKRHSDAVFT 131 |
| Contains: Glucagon-2 (Glucagon II) (Glu II); Glucagon-like peptide 2-II (GLP-2II) | Query 135 RHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 |||||+|||||||+|| ++|+||#| ||+|||| + + +||++|+|| Sbjct 43 RHSQGSFTSDYSKHLDVKQAKDF#VTWLLNTKRRGVDAQAGANLEKRHSDGSFT 95 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKR 166 | +|||| |+||+| + || |++|#++|| | Sbjct 84 NLEKRHSDGSFTNDMNVMLDRMSAKNF#LEWLKQQGR 119 |
| Ambloplites rupestris | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 |||||||+||+ ||+ |+||||#++|||| | |+ |++ |||+|||| Sbjct 1 HSQGTFTNDYTNYLEDRQAQDF#IRWLMNNK--RSGAAEK-----RHADGTFT 45 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDE--FERHAEGTFT 187 +|||+ |||| | | + +||#| | + + | | | || ||+|| Sbjct 36 EKRHADGTFTDDASSDFYDQAIKDF#VAKLKSGQDRREPETDRRREAFSRRHVEGSFT 92 |
| Arvicanthis ansorgei | Query 130 MNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ++ + ||+ | ||||||+ | |+ +#++ |+ || ++| + +||++ || Sbjct 58 VSRNARHADGVFTSDYSRLLGQISAKKY#LESLIG-KRISSSILEDPVPIKRHSDAVFT 114 |
| synthetic construct | Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN---NIAKRHDEFERHAEGTFT 187 +| +||++|||||| | ||+ + |++|#+ ||+ + |+ +| + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEF#IAWLVKGRGRRDFPEEVAIVEELGRRHADGSFS 152 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 165 +||+ |+|+ + + ||+ |+||#+ ||+ || Sbjct 144 RRHADGSFSDEMNTILDNLAARDF#INWLIQTK 175 |
| Phodopus sungorus | Query 139 GTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN---NIAKRHDEFERHAEGTFT 187 |||||| | ||+ + |++|#+ ||+ + |+ + + |||+|+|+ Sbjct 1 GTFTSDVSSYLEGQAAKEF#IAWLVKGRGRRDFPEEVTIVEELGRRHADGSFS 52 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 165 +||+ |+|+ + + ||| +||#+ ||+ || Sbjct 44 RRHADGSFSDEMNTILDSLATRDF#INWLIQTK 75 |
| Contains: Glicentin-related polypeptide (GRPP); Glucagon-1 (Glucagon I); Glucagon-like peptide 1 (Glucagon-like peptide I) | Query 129 QMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 +++ ||||+|||++||||||+ |+||+|#|+|||| | |+ +|++ |||+|||| Sbjct 46 ELSNMKRHSEGTFSNDYSKYLEDRKAQEF#VRWLMNNK--RSGVAEK-----RHADGTFT 97 Query 133 DKRHSQGTFTSDYSKYLDSRRAQDF#VQWL 161 +|||+ |||||| | || + +||#| | Sbjct 88 EKRHADGTFTSDVSSYLKDQAIKDF#VDRL 116 |
| Sus scrofa | Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||| ||||||||||||||||||||||||||#||||||||||+||||||||||||||||||| Sbjct 45 DQMTEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNKNNIAKRHDEFERHAEGTFT 104 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN---NIAKRHDEFERHAEGTFT 187 +| +||++|||||| | ||+ + |++|#+ ||+ + |+ + + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEF#IAWLVKGRGRRDFPEEVTIVEELRRRHADGSFS 152 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 165 +||+ |+|+ + + ||+ +||#+ ||++|| Sbjct 144 RRHADGSFSDEMNTVLDNLATRDF#INWLLHTK 175 |
| Neoceratodus forsteri | Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 | |||||||| |||+| |++| | ||#|| ||||||| ++||| | |||||||+| Sbjct 20 EAKRHSQGTFMSDYAKLLEARHALDF#VQRLMNTKRN-GGVSKRHSEIERHAEGTYT 74 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEF-ERHAEGTFT 187 +| +||++||+||| | ||+ + | +|#|+||+ + |+ +| |||+|| | Sbjct 63 SEIERHAEGTYTSDISSYLEGQAANEF#VRWLLKGRGRRDFSDTDAEEMGRRHADGTIT 120 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 165 +||+ || |+| + |+| ++|#+ ||+|+| Sbjct 112 RRHADGTITNDMNNVLESIATREF#LNWLINSK 143 |
| Canis lupus familiaris | Query 128 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 ||||||||||||||||||||||||||||||#||||||||||+||||||||||||||||||| Sbjct 45 DQMNEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNKNNIAKRHDEFERHAEGTFT 104 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN---NIAKRHDEFERHAEGTFT 187 +| +||++|||||| | ||+ + |++|#+ ||+ + |+ +| + |||+|+|+ Sbjct 93 DEFERHAEGTFTSDVSSYLEGQAAKEF#IAWLVKGRGRRDFPEEVAIVEEFRRRHADGSFS 152 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTK 165 +||+ |+|+ + + ||+ +||#+ ||+ || Sbjct 144 RRHADGSFSDEMNTVLDTLATRDF#INWLLQTK 175 |
| Contains: Glucagon; Glucagon-36 (Oxyntomodulin); Glucagon-like peptide | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 |||||||+|||||||+||||||#|||||+|||+ | ||+||+| Sbjct 1 HSQGTFTNDYSKYLDTRRAQDF#VQWLMSTKRS-GGITXXXXXXXXHADGTYT 51 Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 168 |+ ||+||| | || + |+ |#| || + | Sbjct 45 HADGTYTSDVSSYLQDQAAKKF#VTWLKQGQDRR 77 |
| Hydrolagus colliei | Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 |||+ | |+||||||||+|| +||#||||++|||| | |+ +|||+| +| Sbjct 30 KRHTDGIFSSDYSKYLDNRRTKDF#VQWLLSTKRNGANT----DKTKRHADGIYT 79 Query 131 NEDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNN--IAKRHDEFERHAE 183 ++ |||+ | +||| + | +++ |#|+ | | + +|+ ++||| | | | Sbjct 68 DKTKRHADGIYTSDVASLTDYLKSKRF#VESLSNYNKRQNDRRMSKRHVEGARRTE 122 Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFE 179 | | ++ + +|+| ||+++ |+||#+ ||+ + | + |+ | | Sbjct 116 EGARRTEEDYPNDFSSYLEAKAAKDF#IDWLIK-GQGRRDFAEESREIE 162 |
| Heloderma suspectum, venom, Peptide, 39 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMN 163 | +|||||| || ++ + |#++|| | Sbjct 1 HGEGTFTSDLSKQMEEEAVRLF#IEWLKN 28 |
| Tilapia nilotica=Nile tilapia, Brockmann body, Peptide, 33 aa | Query 139 GTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRN 169 ||+||| | || + |++|#| || + |+ Sbjct 3 GTYTSDVSSYLQDQAAKEF#VSWLKTGRGRRD 33 |
| Amphiuma tridactylum=three-toed amphiumae, pancreas, Peptide, 34 aa | Query 136 HSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNR 168 |+ || ||| | +|+ + ++|#+ ||++ + | Sbjct 1 HADGTLTSDISSFLEKQATKEF#IAWLVSGRGRR 33 |
| Agkistrodon piscivorus | Query 132 EDKRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNIAKRH---DEFERHAEGTFT 187 | +||+ ||+||| | ||+ + |++|#+ ||+| + |+ | | |||+|||| Sbjct 32 EYERHADGTYTSDISSYLEGQAAKEF#IAWLVNGRGRRDFSEGAHTGEDLGRRHADGTFT 90 Query 134 KRHSQGTFTSDYSKYLDSRRAQDF#VQWLMNTKRNRNNI 171 +||+ |||||||+| || |+|#++||+| | + ++ Sbjct 82 RRHADGTFTSDYNKLLDDIATQEF#LKWLINQKVTQRDL 119 Query 149 LDSRRAQDF#VQWLMNTKRNRNNIAKRHDEFERHAEGTFT 187 |+ | ++|#+ | + | +|+ | |+||||+||+| Sbjct 9 LEDREKENF#LDQLAS-----NGLARPHAEYERHADGTYT 42 |
* References
None.