XSB0045 : PREDICTED: similar to von Willebrand factor [Rattus norvegicus]
[ CaMP Format ]
This entry is computationally expanded from SB0030
* Basic Information
| Organism | Rattus norvegicus (Norway rat) |
| Protein Names | similar to von Willebrand factor |
| Gene Names | Vwf; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 2 mRNAs, 32 ESTs, 4 Proteins |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 2811 aa
Average Mass: 0.000 kDa
Monoisotopic Mass: 0.000 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| VWD 1. | 35 | 165 | 31.4 | 3.2e-06 |
| C8 1. | 217 | 291 | 87.9 | 3.6e-23 |
| TIL 1. | 294 | 347 | 41.8 | 2.8e-09 |
| VWD 2. | 387 | 540 | 177.1 | 4.9e-50 |
| C8 2. | 576 | 648 | 122.5 | 1.4e-33 |
| TIL 2. | 651 | 706 | 39.2 | 1.6e-08 |
| --- cleavage 762 --- |
| TIL 3. | 775 | 826 | 26.8 | 9.1e-05 |
| VWD 3. | 866 | 1012 | 145.0 | 2.4e-40 |
| C8 3. | 1052 | 1126 | 115.2 | 2.2e-31 |
| TIL 4. | 1141 | 1195 | 34.2 | 5.3e-07 |
| Granulin 1. | 1204 | 1235 | -18.7 | 3.8 |
| VWA 1. | 1276 | 1452 | 108.0 | 3.2e-29 |
| VWA 2. | 1497 | 1663 | 169.8 | 7.7e-48 |
| VWA 3. | 1690 | 1857 | 131.6 | 2.5e-36 |
| fn1 1. | 1878 | 1918 | -8.7 | 8.4 |
| VWD 4. | 1949 | 2101 | 126.3 | 1e-34 |
| C8 4. | 2131 | 2199 | 92.4 | 1.5e-24 |
| TIL 5. | 2202 | 2253 | 5.9 | 0.01 |
| VWC 1. | 2256 | 2324 | 73.4 | 8.3e-19 |
| Laminin_EGF 1. | 2339 | 2374 | -25.6 | 9.2 |
| VWC 2. | 2430 | 2493 | 81.1 | 3.9e-21 |
| Antistasin 1. | 2547 | 2568 | 7.4 | 0.29 |
| VWC 3. | 2580 | 2642 | 60.1 | 8.5e-15 |
| Cys_knot 1. | 2714 | 2809 | -29.6 | 0.35 |
3. Sequence Information
Fasta Sequence: XSB0045.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] SSPLSHRSKR762-SLSCRPPMVK
Arg762 
Ser
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Ser753 | Ser754 | Pro755 | Leu756 | Ser757 | His758 | Arg759 | Ser760 | Lys761 | Arg762 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ser763 | Leu764 | Ser765 | Cys766 | Arg767 | Pro768 | Pro769 | Met770 | Val771 | Lys772 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
GFMHCTTSGASGSLLPNIVLSSPLSHRSKRSLSCRPPMVKLVCPADNPRAQGLECAKTCQ
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Rattus norvegicus |
128.00 |
2 |
PREDICTED: similar to von Willebrand factor |
| 2 |
Mus musculus |
120.00 |
4 |
von Willebrand factor |
| 3 |
Contains: von Willebrand antigen 2 (von Willebrand antigen II) |
120.00 |
2 |
VWF_MOUSE von Willebrand factor precursor (vWF) |
| 4 |
N/A |
118.00 |
3 |
- |
| 5 |
Canis lupus familiaris |
118.00 |
1 |
von Willebrand factor |
| 6 |
Canis familiaris |
118.00 |
1 |
von Willebrand factor |
| 7 |
Bos taurus |
117.00 |
2 |
PREDICTED: similar to von Willebrand factor precur |
| 8 |
Sus scrofa |
115.00 |
2 |
VWF_PIG von Willebrand factor precursor (vWF) gb |
| 9 |
Homo sapiens |
112.00 |
6 |
von Willebrand factor preproprotein |
| 10 |
Pan troglodytes |
112.00 |
2 |
PREDICTED: von Willebrand factor isoform 2 |
| 11 |
Oryctolagus cuniculus |
98.20 |
1 |
von Willebrand factor; vWF |
| 12 |
Gallus gallus |
85.50 |
1 |
PREDICTED: similar to von Willebrand factor precur |
| 13 |
Tetraodon nigroviridis |
34.30 |
1 |
unnamed protein product |
Top-ranked sequences
| organism | matching |
|---|
| Rattus norvegicus |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
|
| Mus musculus |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
||||||||| |||||+ ||||||||||||#||||||||||||||||||||||||||||||
Sbjct 734 GFMHCTTSGTLGSLLPDTVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 793
|
| Contains: von Willebrand antigen 2 (von Willebrand antigen II) |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
||||||||| |||||+ ||||||||||||#||||||||||||||||||||||||||||||
Sbjct 734 GFMHCTTSGTLGSLLPDTVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 793
|
| N/A |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
||||||||| |||||| ||||| ||||||#||||||||||||||||||||+|||||||||
Sbjct 734 GFMHCTTSGGLGSLLPNPVLSSPRSHRSKR#SLSCRPPMVKLVCPADNPRAEGLECAKTCQ 793
|
| Canis lupus familiaris |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
||||||||| |||||| ||||| ||||||#||||||||||||||||||||+|||||||||
Sbjct 734 GFMHCTTSGGLGSLLPNPVLSSPRSHRSKR#SLSCRPPMVKLVCPADNPRAEGLECAKTCQ 793
|
| Canis familiaris |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
||||||||| |||||| ||||| ||||||#||||||||||||||||||||+|||||||||
Sbjct 734 GFMHCTTSGGLGSLLPNPVLSSPRSHRSKR#SLSCRPPMVKLVCPADNPRAEGLECAKTCQ 793
|
| Bos taurus |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
|||||+|||| ||||| ||||||||||||#||||||||||+|||||||||+|||| ||||
Sbjct 749 GFMHCSTSGAPGSLLPEAVLSSPLSHRSKR#SLSCRPPMVKVVCPADNPRAEGLECTKTCQ 808
|
| Sus scrofa |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
|||||+ +|| ||| | +||||||||||||#||||||||||||||||||||+|||||||||
Sbjct 408 GFMHCSRAGAPGSLQPEVVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAEGLECAKTCQ 467
|
| Homo sapiens |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
|||||| || |||||+ ||||||||||||#||||||||||||||||| ||+|||| ||||
Sbjct 734 GFMHCTMSGVPGSLLPDAVLSSPLSHRSKR#SLSCRPPMVKLVCPADNLRAEGLECTKTCQ 793
|
| Pan troglodytes |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
|||||| || |||||+ ||||||||||||#||||||||||||||||| +|+|||||||||
Sbjct 734 GFMHCTMSGVPGSLLPDAVLSSPLSHRSKR#SLSCRPPMVKLVCPADNLQAEGLECAKTCQ 793
|
| Oryctolagus cuniculus |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
||||||+|| |||||+ + | |||||#|||||||||| ||| |||||+|||||||||
Sbjct 12 GFMHCTSSGRPGSLLPD----TALPHRSKR#SLSCRPPMVKFVCPHDNPRAEGLECAKTCQ 67
|
| Gallus gallus |
Query 733 GFMHCTTSGASGSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
|||||+ | | |+|||++ | | ||#||+|| ||| |+|| +||||+|||||||||
Sbjct 731 GFMHCSKSKAPGALLPDVFTDEKPSARIKR#SLTCRSPMVTLICPENNPRAEGLECAKTCQ 790
|
| Tetraodon nigroviridis |
Query 735 MHCTTSGAS-GSLLPNIVLSSPLSHRSKR#SLSCRPPMVKLVCPADNPRAQGLECAKTCQ 792
+|| || | | + | +|#|+ | | +++| | |+|||+|||
Sbjct 822 LHCLTSSMMMTSHCPEVQL--------RR#SVQCAPGLIRLNCDTGE---NGIECARTCQ 869
|
